Sofia Lima (0013-8CA6-2D1C)

Curriculum Vitae

Sofia Lima

Sofia Lima (SL) is an Assistant Researcher at ICBAS - Abel Salazar Institute of Biomedical Sciences and LAQV/REQUIMTE position awarded by the CEEC Institutional under One Health Initiative. Completed the PhD in Chemistry in 2007 at the Universidade do Porto Faculdade de Ciências, and the International Master of Science in Biotechnology in 1999 by De Montfort University, United Kingdom. SL graduated in Microbiology in 1998 by Universidade Católica Portuguesa Escola Superior de Biotecnologia. SL is focused in the study of cell-nanomaterials interactions using biochemical and biophysical techniques, to unravel related mechanisms of action. Improve knowledge on nanomaterials safety is crucial to assure their emerging introduction in consumer goods (food and health). SL interest in the development of drug delivery systems able to overcome the barriers (skin and gastrointestinal) lead to the exploitation of natural compounds as tools to enhance permeation and thus modulate biological processes. Published 93 articles in journals (75% Q1), 89 were published independently from SL's PhD supervisor and 35 as corresponding author. SL has an h-index of 30 (scopus) and was cited over 2850 times. SL is also the editor of 2 books, 4 invited book chapters and a national patent. SL supervised 3 PhD thesis and is the main supervisor of 2 PhD students and co-supervisor of 3. Supervised or co-supervised 16 MSc dissertation(s) and participated in the supervision of students (12) on a mobility program from Morocco, Italy, the United Kingdom, Croatia, Greece, Malasia and Turkey. Has received 11 awards and/or honors. Participates and/or participated as Principal investigator in 8 project(s) and Researcher in 18 project(s) funded by national or international funds. SL actively participates in COST Actions and in science awareness activities. SL participated in short-term scientific missions to different national and international laboratories in order to widen her scientific knowledge and know-how (e.g. Alba synchrotron, Barcelona). SL has been involved in several grant reviewing processes for international funding agencies (GWIS; NSC - Poland; ISF - Israel; University of Porto - Portugal; University Bordeaux and ANR - France; European Commission). Additionally, SL has been in the organization of Advanced Courses and Hands-on-Workshops. Works in the area(s) of Chemistry (mainly, polymer chemistry and colloidal chemistry) and Health Sciences with emphasis on Immunology and Nanomaterials for Pharmaceutical and Food applications. keywords: animal nutrition; marine-based hydrogels; fucoidan/chitosan nanoparticles; mannosylated nanoparticles; gold nanoparticles; lipid nanoparticles; liposomes; cutaneous leishmaniasis; leprae; leishmaniose; sleeping sickness; atopic dermatitis; psoriasis; magnetic hyperthermia; nutraceuticals; pH-responsive nanoparticles; photodynamic therapy; PLA nanoparticles; PLGA nanoparticles; pegylated nanoparticles; theranostic nanoparticles.

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Identificação

Identificação pessoal

Nome completo: Sofia Lima

Identificadores de autor

Ciência ID: 0013-8CA6-2D1C
ORCID iD: 0000-0001-8777-5877
Researcher Id: D-7026-2013
Scopus Author Id: 57216898243

Endereços de correio eletrónico

slima@ff.up.pt (Profissional)
slima@icbas.up.pt (Profissional)

Moradas

Instituto de Ciências Biomédicas Abel Salazar da Universidade do Porto. Rua de Jorge Viterbo Ferreira, 228, 4050-313, Porto, Porto, Portugal (Profissional)

Websites

https://www.requimte.pt/laqv/people/sofia-antunes-costa-lima (Profissional)

Domínios de atuação

Ciências Exatas - Química - Ciência de Polímeros
Ciências Exatas - Química - Química de Colóides
Ciências Médicas e da Saúde - Ciências da Saúde - Doenças Infeciosas
Ciências Médicas e da Saúde - Medicina Básica - Imunologia
Ciências da Engenharia e Tecnologias - Nanotecnologia - Nanomateriais

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão
Inglês	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador independente (B1)	Utilizador proficiente (C1)
Inglês	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador independente (B1)	Utilizador proficiente (C1)
Francês	Utilizador elementar (A1)	Utilizador independente (B1)	Utilizador elementar (A1)	Utilizador elementar (A1)
Espanhol; Castelhano	Utilizador elementar (A1)	Utilizador elementar (A1)	Utilizador elementar (A1)	Utilizador elementar (A1)

Formação

	Grau	Classificação
2007/11/07 Concluído	PhD in Chemistry (Doutoramento) Universidade do Porto Faculdade de Ciências, Portugal "Structural and functional activity of P-glycoprotein membrane transporter in the presence of benzodiazepines and tuberculostatic drugs. " (TESE/DISSERTAÇÃO)
1999/07/31 Concluído	International Master of Science in Biotechnology (Mestrado) De Montfort University, Reino Unido "Production of oral vaccines in "Solanum tuberosum L"" (TESE/DISSERTAÇÃO)
1998/06/30 Concluído	Microbiology (Licenciatura) Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal "Identification of "Serra da Estrela" Cheese isolated lactic bacteria by SDS-PAGE" (TESE/DISSERTAÇÃO)

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2022/09/01 - Atual	Investigador Auxiliar (carreira) (Investigação)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
	Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2019/04/06 - 2022/08/31	Investigador Auxiliar (carreira) (Investigação)	REQUIMTE, Portugal
	REQUIMTE LAQV Porto, Portugal
2016/04/06 - 2019/04/05	Investigador (Investigação)	REQUIMTE LAQV Porto, Portugal
	Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
2013/03/18 - 2015/06/30	Investigador (Investigação)	REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
	REQUIMTE, Portugal
2007/11/15 - 2013/03/17	Investigador (Investigação)	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

2002/03/01 - 2007/11/07	Investigador (Investigação)	REQUIMTE, Portugal

Docência no Ensino Superior

	Categoria Profissional Instituição de acolhimento	Empregador
2021/09/25 - 2022/07/31	Professor Auxiliar Convidado (Docente Universitário)	Instituto Universitário de Ciências da Saúde, Portugal

2020/09/14 - 2021/07/31	Professor Auxiliar Convidado (Docente Universitário)	Instituto Universitário de Ciências da Saúde, Portugal

2019/10/01 - 2020/07/31	Professor Auxiliar Convidado (Docente Universitário)	Instituto Universitário de Ciências da Saúde, Portugal
	Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2018/10/01 - 2019/02/28	Professor Auxiliar Convidado (Docente Universitário)	Instituto Universitário de Ciências da Saúde, Portugal

2017/10/01 - 2018/02/28	Professor Auxiliar Convidado (Docente Universitário)	Instituto Universitário de Ciências da Saúde, Portugal

2016/10/01 - 2017/02/28	Professor Auxiliar Convidado (Docente Universitário)	Instituto Universitário de Ciências da Saúde, Portugal

2015/10/01 - 2016/02/28	Professor Auxiliar Convidado (Docente Universitário)	Instituto Universitário de Ciências da Saúde, Portugal
	Instituto Universitário de Ciências da Saúde, Portugal

Outros

	Categoria Profissional Instituição de acolhimento	Empregador
2007/10/01 - 2008/06/30	Educational trainer	Associação para a Escola Superior de Biotecnologia da Universidade Católica Portuguesa, Portugal

2007/03/01 - 2007/06/29	Educational trainer	Forpime, Portugal

2000/03/01 - 2002/02/28	Invited Assistant Lecturer	Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal

1999/11/02 - 2001/12/31	Researcher Assistant	Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal

1999/02/01 - 1999/07/30	Graduated researcher	Wageningen University and Research Wageningen Plant Research, Países Baixos

1997/10/01 - 1998/07/31	Undergraduated Researcher	Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal

Projetos

Bolsa

	Designação	Financiadores
2002/03/01 - Atual	Avaliação do efeito de iões de metais de transição no transporte de fármacos pela P-glicoproteína PRAXIS XXI BD/4613/2001) Bolseiro de Doutoramento	Fundação para a Ciência e a Tecnologia
2002 - Atual	Evaluation of the structure and function of P-glycoprotein, membrane transporter, in the presence of benzodiazepines and tuberculostatics BPD/37880/2007 Bolseiro de Doutoramento Universidade do Porto Faculdade de Ciências, Portugal	Fundação para a Ciência e a Tecnologia
1998 - Atual	Production of oral vaccines in Solanum tuberosum L PRAXIS XXI BM/20357/98 Bolseiro de Mestrado	Fundação para a Ciência e a Tecnologia
2008/04/01 - 2013/03/15	Development of BNIP polyamine drug delivery systems, liposome and nanoparticles, to target specially Leishmania infected macrophages and dendritic cells BPD/37880/2007	Fundação para a Ciência e a Tecnologia
1998/04/01 - 2000/03/31	Mare Nostrum Ministerio Defesa Nacional Investigador Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal	Governo da Republica Portuguesa Ministério da Defesa Nacional
1999/01/01 - 1999/06/30	Production of oral vaccines in Solanum tuberosum L. PRAXIS XXI BM/20357/98 Bolseiro de Mestrado De Montfort University, Reino Unido	Fundação para a Ciência e a Tecnologia

Projeto

	Designação	Financiadores
2022/10/01 - Atual	NovInDog - Novos Ingredientes Proteicos Funcionais para a Alimentação de Cães: uma Abordagem Sustentável POCI-01-0247-FEDER-047003 Investigador	Em curso
2022/09/01 - 2028/08/31	Nanotechnological approaches for animal health and growth towards a sustainable environment CEECINST/00007/2021/CP2775/CT0001 10.54499/CEECINST/00007/2021/CP2775/CT0001 Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2025/02/01 - 2026/07/31	Advanced Nanotechnology for Functional Nutrition in Aquaculture 2023.14508.PEX Investigador responsável Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2021/01/01 - 2025/12/31	Laboratório Associado para a Química Verde - Tecnologias e Processos Limpos LA/P/0008/2020 10.54499/LA/P/0008/2020 Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Universidade Nova de Lisboa, Portugal Unidade de Investigação Vidro e Cerâmica para as Artes, Portugal Universidade de Aveiro, Portugal Universidade de Évora, Portugal Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2022/01/01 - 2024/06/30	CoSki - Collaborative Initiative for Skin Research EEA Grant Investigador responsável REQUIMTE LAQV Porto, Portugal	EEA Grants Em curso
2022/01/01 - 2023/06/30	Cellulose-based iron nanofertilizers for sustainable growth of soybean plants EXPL/QUI-QIN/0411/2021 Investigador REQUIMTE LAQV Porto, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2022/04/01 - 2023/03/31	Bacterial cell-specific targeting and nanoparticle-mediated bactericidal action against the most common pathogens colonizing diabetic foot ulcers ESCMID Research Grants 2022 Investigador Universidade do Minho, Portugal REQUIMTE LAQV Porto, Portugal	European Society of Clinical Microbiology and Infectious Diseases
2022/04 - 2023/03	Bacterial cell-specific targeting and nanoparticle-mediated bactericidal action against the most common pathogens colonizing diabetic foot ulcers ESCMID Research Grants 2022	European Society of Clinical Microbiology and Infectious Diseases
2022/11/02 - 2022/11/06	The effect of marine polymers-based nanoparticles on the skin structural organization towards skin delivery. 2021025041 Investigador responsável	Alba Synchroton Concluído
2019/04/06 - 2022/08/31	SeaNano4sNTDs: Marine-based nanotechnological approaches for skin-related Neglected Tropical Diseases therapies CEECIND/01620/2017/CP1427/CT0002 10.54499/CEECIND/01620/2017/CP1427/CT0002 Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2018/07/01 - 2021/06/30	3Ds – transDermic aDministration of Drugs PTDC/QUI-COL/30834/2017 Investigador responsável REQUIMTE LAQV Porto, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2018/07/01 - 2021/06/30	Circumventing surgical removal of biofilms infected implants: a nano-based, selective and targeted approach PTDC/NAN-MAT/31444/2017 Investigador REQUIMTE LAQV Porto, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2020/07/08 - 2021/01/08	nano2Prevent nano2Prevent Investigador REQUIMTE LAQV Porto, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2019/01/01 - 2019/12/31	Unidade de Ciências Biomoleculares Aplicadas UID/Multi/04378/2019 Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Unidade de Ciências Biomoleculares Aplicadas, Portugal Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal Universidade do Porto Faculdade de Ciências, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2016/06/01 - 2019/05/31	Navigating through marine-derived fungi: bioprospection and synthesis of bioactive secondary metabolites and analogues as chemotherapic agents PTDC/MAR-BIO/4694/2014 Investigador	Fundação para a Ciência e a Tecnologia Concluído
2012/05/05 - 2015/05/04	Cell communication by Leishmania microvesicles Provided by PTCRIS: 118644 Investigador Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia
2012/10 - 2013/12	Therapeutic efficacy and safety of BNIPDaoct-loaded PLGA nanoparticles for the treatment of visceral leishmaniasis IJUP2011-227	Banco Santander Totta
2011/03 - 2013/12	Development of new drug delivery systems based on bisnaphthalimidopropyl derivatives compounds liposomal formulation for pancreatic cancer and leishmaniasis drug therapy Provided by PTCRIS: 113151 PTDC/ SAU-ENB/ 113151/ 2009 Investigador responsável Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2011/04/01 - 2013/03/31	Development of a new immunological screening method for leishmaniasis using colloidal gold nanoparticles info:eu-repo/grantAgreement/FCT/5876-PPCDTI/110732/PT Provided by PTCRIS: 110732 Investigador Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Universidade do Algarve Faculdade de Ciências e Tecnologia Fundação para a Ciência e a Tecnologia
2009/11/01 - 2012/12/31	Nanotechnology as a tool towards Leishmaniasis and Human African Trypanosomiasis therapy P-105348 Investigador responsável Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação Calouste Gulbenkian Concluído
2011/01/01 - 2011/12/31	Evaluation of anti-Leishmania compounds released from polymeric nanoparticles projeto 155 Investigador responsável Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Banco Santander Totta Concluído
2011/01/01 - 2011/12/31	Lipid nanocarriers for dermal and transdermal drug delivery intending the treatment of cellulite by inducing adipocytes lipolysis Pluridisciplicar 98 Investigador REQUIMTE LAQV Porto, Portugal	Banco Santander Totta
2006/10/01 - 2009/12/31	The Leishmania TDR1 family-related gene: functional studies and evaluation of TDR1 recombinant protein and knockout vaccines against leishmaniasis. Provided by PTCRIS: 65047 PTDC/CVT/65047/2006 Investigador Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluído

Outro

	Designação	Financiadores
2024/03/20 - Atual	COST Action CA22160 - Enhancing knowledge of BIOmolecular solutions for the well-being of European AQUAculture sector (BIOAQUA) CA22160 Investigador
2022/09/26 - Atual	COST Action CA21108 - European Network for Skin Engineering and Modeling CA21108 Investigador
2024/10/22 - 2028/10/21	COST Action CA23132 - Magnetic Particle Imaging for next-generation theranostics and medical research (NexMPI) CA22160 Investigador Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal	Em curso
2019/04/04 - 2022/08/31	SeaNano4sNTDs: Marine-based nanotechnological approaches for skin-related Neglected Tropical Diseases therapies CEECIND/01620/2017 Investigador responsável	Fundação para a Ciência e a Tecnologia
2021/11/30 - 2022/05/31	C19-VisualDetect C19-VisualDetect Investigador REQUIMTE LAQV Porto, Portugal	Universidade do Porto Em curso
2018 - 2022	CA16205: European Network on Understanding Gastrointestinal Absorption-related Processes (UNGAP) CA16205 Investigador European Cooperation in Science and Technology, Bélgica	European Cooperation in Science and Technology
2016/04/07 - 2019/03/30	FOODnanoHEALTH - Qualidade e Segurança Alimentar – uma abordagem (nano)tecnológica NORTE-01-0145-FEDER-000011 Investigador Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal	Comissao de Coordenacao e Desenvolvimento Regional do Norte Concluído
2014 - 2018	CM1307 "Targeted chemotherapy towards diseases caused by endoparasites" CM1307 Investigador European Cooperation in Science and Technology, Bélgica	European Cooperation in Science and Technology
2014 - 2018	TD1402 "Multifunctional Nanoparticles for Magnetic Hyperthermia and Indirect Radiation Therapy (RADIOMAG)" TD1402 Investigador European Cooperation in Science and Technology, Bélgica	European Cooperation in Science and Technology
2013/03/17 - 2015/06/30	Nanoquímica Norte-07-0124-FEDER-000067 Investigador Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal	Concluído
2012 - 2014	TD1004 "Theranostics Imaging and Therapy: An Action to Develop Novel Nanosized Systems for Imaging-Guided Drug Delivery" TD 1004 Investigador European Cooperation in Science and Technology, Bélgica	European Cooperation in Science and Technology

Produções

Publicações

Artigo em revista	Ricardo Magalhães; Claudia Nunes; Sofia A. Costa Lima; David Navas; Carolina Redondo; Rafael Morales; Miriam Jaafar; Célia Tavares de Sousa. "Vortex Nanodiscs Functionalization to Overcome Macrophage Recognition for Efficient Theragnosis Applications". Advanced Engineering Materials (2024): https://doi.org/10.1002/adem.202400369. 10.1002/adem.202400369 Francisco Faísca; Željko Petrovski; Inês Grilo; Sofia A. C. Lima; Miguel M. Santos; Luis C. Branco. "Synthesis, Characterization, Bioavailability and Antimicrobial Studies of Cefuroxime-Based Organic Salts and Ionic Liquids". Pharmaceutics (2024): https://doi.org/10.3390/pharmaceutics16101291. 10.3390/pharmaceutics16101291 Célia Marques; Liliana Grenho; Maria Helena Fernandes; Sofia A. Costa Lima. "Improving the Antimicrobial Potency of Berberine for Endodontic Canal Irrigation Using Polymeric Nanoparticles". Pharmaceutics (2024): https://doi.org/10.3390/pharmaceutics16060786. 10.3390/pharmaceutics16060786 Andreia Marinho; Catarina Leal Seabra; Sofia A. C. Lima; Alexandre Lobo-da-Cunha; Salette Reis; Cláudia Nunes. "Empowering Naringin’s Anti-Inflammatory Effects through Nanoencapsulation". International Journal of Molecular Sciences (2024): https://doi.org/10.3390/ijms25084152. 10.3390/ijms25084152 Joana Guilherme-Fernandes; Tiago Aires; António J. M. Fonseca; Timur Yergaliyev; Amélia Camarinha-Silva; Costa Lima, S A; Margarida R. G. Maia; Ana R. J. Cabrita. "Squid meal and shrimp hydrolysate as novel protein sources for dog food". Frontiers in Veterinary Science 11 (2024): Acesso aberto • 10.3389/fvets.2024.1360939 Joana Guilherme-Fernandes; António J. M. Fonseca; Tiago Aires; Costa Lima, Sofia A.; Maia, Margarida R. G.; Ana R. J. Cabrita. "Unveiling the effects of shrimp hydrolysate as a dietary ingredient in healthy adult Beagle dogs". Journal of Animal Science 102 (2024): skae280. https://pubmed.ncbi.nlm.nih.gov/39292957/. Aceite para publicação • 10.1093/jas/skae280 Shakel, Zinaida; Costa Lima, S A; Salette Reis. "Strategies to make human skin models based on cellular senescence for ageing research". Ageing Res Rev. 100 (2024): 102430.. Aceite para publicação Kristina Radic; Ana Isabel Barbosa; Salette Reis; Marijan Marijan; Sofia Antunes Costa Lima; Dubravka Vitali Cepo. "Preparation of astaxanthin/zeaxanthin-loaded nanostructured lipid carriers for enhanced bioavailability: Characterization-, stability-and permeability study". Acta Pharmaceutica (2023): https://doi.org/10.2478/acph-2023-0038. 10.2478/acph-2023-0038 Katerina Spanou; Ana Isabel Barbosa; Anastasia Detsi; Sofia A. Costa Lima; Salette Reis. "Development and characterization of gel-like matrix containing genistein for skin application". Journal of Drug Delivery Science and Technology (2023): https://doi.org/10.1016/j.jddst.2023.105119. 10.1016/j.jddst.2023.105119 Célia Marques; Maria Helena Fernandes; Sofia A. Costa Lima. "Elucidating Berberine's Therapeutic and Photosensitizer Potential through Nanomedicine Tools". Pharmaceutics (2023): https://doi.org/10.3390/pharmaceutics15092282. 10.3390/pharmaceutics15092282 Filipa Serrasqueiro; Ana Isabel Barbosa; Sofia A. Costa Lima; Salette Reis. "Targeting the Mannose Receptor with Functionalized Fucoidan/Chitosan Nanoparticles Triggers the Classical Activation of Macrophages". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24129908. 10.3390/ijms24129908 Costa Lima, S A. "Rational design of magnetoliposomes for enhanced interaction with bacterial membrane models". Biochimica et Biophysica Acta (BBA) - Biomembranes 1865 (2023): 184115. 10.1016/j.bbamem.2022.184115 Barbosa, Ana Isabel; Lima, Sofia A. Costa; Yousef, Ibraheem; Reis, Salette. "Evaluating the Skin Interactions and Permeation of Alginate/Fucoidan Hydrogels Per Se and Associated with Different Essential Oils". Pharmaceutics 15 1 (2023): 190. http://dx.doi.org/10.3390/pharmaceutics15010190. 10.3390/pharmaceutics15010190 Sarah A. P. Pereira; Jan Romano-deGea; Ana Isabel Barbosa; Costa Lima, S A; Paul J. Dyson; M. Lúcia M. F. S. Saraiva. "Fine-tuning the cytotoxicity of ruthenium(ii) arene compounds to enhance selectivity against breast cancers". Dalton Transactions 52 (2023): 11679-11690. doi: 10.1039/d3dt02037a. Acesso aberto • 10.1039/d3dt02037a Costa Lima, S A; Ana Isabel, Barbosa; Cláudia, Nunes; Ibraheem, Yousef; Salette, Reis. Autor correspondente: Costa Lima, S A. "Synchrotron-based infrared microspectroscopy of polymeric nanoparticles and skin: Unveiling molecular interactions to enhance permeation". Chemistry and Physics of Lipids 249 (2022): 105254. Acesso aberto • 10.1016/j.chemphyslip.2022.105254 A. R. J. Cabrita; Joana Fernandes; Inês Maria Valente; Agostinho Almeida; Sofia A. Costa Lima; AJM Fonseca; M.R.G. Maia. "Nutritional Composition and Untargeted Metabolomics Reveal the Potential of Tetradesmus obliquus, Chlorella vulgaris and Nannochloropsis oceanica as Valuable Nutrient Sources for Dogs". Animals (2022): https://www.mdpi.com/2076-2615/12/19/2643. 10.3390/ani12192643 Tânia M. T. Guimarães; Tânia Moniz; Cláudia Nunes; Maya Margaritova Zaharieva; Mila Kaleva; Krassimira Yoncheva; Hristo Najdenski; Sofia A. Costa Lima; Salette Reis. "Polymeric Microneedles for Transdermal Delivery of Rivastigmine: Design and Application in Skin Mimetic Model". Pharmaceutics 14 4 (2022): 752-752. https://doi.org/10.3390/pharmaceutics14040752. 10.3390/pharmaceutics14040752 Adouni, Khaoula; Júlio, Ana; Santos-Buelga, Celestino; González-Paramás, Ana M.; Filipe, Patrícia; Rijo, Patricia; Costa Lima, Sofia A.; et al. "Roots and rhizomes of wild Asparagus: Nutritional composition, bioactivity and nanoencapsulation of the most potent extract". Food Bioscience 45 (2022): 101334. http://dx.doi.org/10.1016/j.fbio.2021.101334. Publicado • 10.1016/j.fbio.2021.101334 Renata Basto; Raquel Andrade; Cláudia Nunes; Sofia A. Costa Lima; Salette Reis. "Topical Delivery of Niacinamide to Skin Using Hybrid Nanogels Enhances Photoprotection Effect". Pharmaceutics 13 11 (2021): 1968-1968. https://doi.org/10.3390/pharmaceutics13111968. 10.3390/pharmaceutics13111968 Tânia Moniz; Sofia A. Costa Lima; Salette Reis. "Protocol for the Isolation of Stratum Corneum from Pig Ear Skin: Evaluation of the Trypsin Digestion Conditions". Methods and Protocols (2021): https://doi.org/10.3390/mps4040080. 10.3390/mps4040080 Fonseca, Magda; Macedo, Ana S.; Lima, Sofia A. Costa; Reis, Salette; Soares, Raquel; Fonte, Pedro. "Evaluation of the Antitumour and Antiproliferative Effect of Xanthohumol-Loaded PLGA Nanoparticles on Melanoma". Materials 14 21 (2021): 6421. http://dx.doi.org/10.3390/ma14216421. Publicado • 10.3390/ma14216421 Rita M. Pinto; Claudia Monteiro; Sofia A. Costa Lima; Susana Casal; Patrick Van Dijck; M. Cristina L. Martins; Cláudia Nunes; Salette Reis. "N-Acetyl-l-cysteine-Loaded Nanosystems as a Promising Therapeutic Approach Toward the Eradication of Pseudomonas aeruginosa Biofilms". ACS Applied Materials & Interfaces (2021): https://doi.org/10.1021/acsami.1c05124. 10.1021/acsami.1c05124 Raquel Costa; Sofia A. Costa Lima; Paula Gameiro; Salette Reis. "On the Development of a Cutaneous Flavonoid Delivery System: Advances and Limitations". Antioxidants 10 9 (2021): 1376-1376. https://doi.org/10.3390/antiox10091376. 10.3390/antiox10091376 Joana Costa Antunes; Catarina Leal Seabra; Joana Margarida Domingues; Marta Oliveira Teixeira; Cláudia Nunes; Sofia Antunes Costa-Lima; Natália Cândido Homem; et al. "Drug Targeting of Inflammatory Bowel Diseases by Biomolecules". Nanomaterials 11 8 (2021): 2035-2035. https://doi.org/10.3390/nano11082035. 10.3390/nano11082035 Moniz, Tânia; Costa Lima, Sofia A.; Reis, Salette. "Marine polymeric microneedles for transdermal drug delivery". Carbohydrate Polymers 266 (2021): 118098. http://dx.doi.org/10.1016/j.carbpol.2021.118098. Publicado • 10.1016/j.carbpol.2021.118098 Ana Isabel Barbosa; Tiago Torres; Sofia A. Costa Lima; Salette Reis. "Hydrogels: A Promising Vehicle for the Topical Management of Atopic Dermatitis". Advanced Therapeutics (2021): https://doi.org/10.1002/adtp.202100028. 10.1002/adtp.202100028 Sofia A. Costa Lima; Salette Reis. "Polymeric Carriers for Biomedical and Nanomedicine Application". Polymers 13 8 (2021): 1261-1261. https://doi.org/10.3390/polym13081261. 10.3390/polym13081261 Célia T. Sousa; A. Marinho; Andreia Granja; Cláudia Nunes; João P. Araújo; Costa Lima, S A; S. Moraes; Salette Reis. "Targeted nanostructured lipid carriers for doxorubicin oral delivery". International Journal of Pharmaceutics 592 (2021): 120029. 10.1016/j.ijpharm.2020.120029 Vieira, Alexandre C.C.; Chaves, Luíse L.; Pinheiro, Marina; Lima, Sofia Costa; Neto, Pedro José Rolim; Ferreira, Domingos; Sarmento, Bruno; Reis, Salette. "Lipid nanoparticles coated with chitosan using a one-step association method to target rifampicin to alveolar macrophages". Carbohydrate Polymers 252 (2021): 116978. http://dx.doi.org/10.1016/j.carbpol.2020.116978. Aceite para publicação • 10.1016/j.carbpol.2020.116978 Moraes, S.; Marinho, A.; Lima, S.; Granja, A.; Araújo, J.P.; Reis, S.; Sousa, C.T.; Nunes, C.. "Targeted nanostructured lipid carriers for doxorubicin oral delivery". International Journal of Pharmaceutics 592 (2021): 120029. http://dx.doi.org/10.1016/j.ijpharm.2020.120029. Publicado • 10.1016/j.ijpharm.2020.120029 Raquel G. D. Andrade; Bruno Reis; Benjamin Costas; Sofia A. Costa Lima; Salette Reis. "Modulation of Macrophages M1/M2 Polarization Using Carbohydrate-Functionalized Polymeric Nanoparticles". Polymers 13 1 (2020): 88-88. https://doi.org/10.3390/polym13010088. 10.3390/polym13010088 Luíse L. Chaves; Yuri Patriota; José L. Soares-Sobrinho; Alexandre C. C. Vieira; Sofia A. Costa Lima; Salette Reis. "Drug Delivery Systems on Leprosy Therapy: Moving Towards Eradication?". Pharmaceutics (2020): https://doi.org/10.3390/pharmaceutics12121202. 10.3390/pharmaceutics12121202 Moniz, Tânia; Costa Lima, Sofia A.; Reis, Salette. "Application of the human stratum corneum lipid-based mimetic model in assessment of drug-loaded nanoparticles for skin administration". International Journal of Pharmaceutics 591 (2020): 119960. http://dx.doi.org/10.1016/j.ijpharm.2020.119960. Publicado • 10.1016/j.ijpharm.2020.119960 Ludovico Esposito; Ana Isabel Barbosa; Tânia Moniz; Sofia Costa Lima; Paulo Costa; Christian Celia; Salette Reis. "Design and Characterization of Sodium Alginate and Poly(vinyl) Alcohol Hydrogels for Enhanced Skin Delivery of Quercetin". Pharmaceutics (2020): https://doi.org/10.3390/pharmaceutics12121149. 10.3390/pharmaceutics12121149 Ong, Yong Sze; Bañobre-López, Manuel; Costa Lima, Sofia A.; Reis, Salette. "A multifunctional nanomedicine platform for co-delivery of methotrexate and mild hyperthermia towards breast cancer therapy". Materials Science and Engineering: C 116 (2020): 111255. http://dx.doi.org/10.1016/j.msec.2020.111255. 10.1016/j.msec.2020.111255 Daniela Resende; Sofia A. Costa Lima; Salette Reis. "Nanoencapsulation approaches for oral delivery of vitamin A". Colloids and Surfaces B: Biointerfaces (2020): 111121-111121. https://doi.org/10.1016/j.colsurfb.2020.111121. 10.1016/j.colsurfb.2020.111121 Moniz, Tânia; Costa Lima, Sofia A.; Reis, Salette. "Human skin models: From healthy to disease-mimetic systems; characteristics and applications". British Journal of Pharmacology (2020): http://dx.doi.org/10.1111/bph.15184. 10.1111/bph.15184 Oliver, Miquel; Kudlak, Blazej; Wieczerzak, Monika; Reis, Salette; Lima, Sofia A.C.; Segundo, Marcela A.; Miró, Manuel. "Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants". Science of The Total Environment 719 (2020): 137358. http://dx.doi.org/10.1016/j.scitotenv.2020.137358. 10.1016/j.scitotenv.2020.137358 Maria Inês Silva; Ana Isabel Barbosa; Sofia A. Costa Lima; Paulo Costa; Tiago Torres; Salette Reis; Silva, Maria Inês; et al. "Freeze-Dried Softisan® 649-Based Lipid Nanoparticles for Enhanced Skin Delivery of Cyclosporine A". Nanomaterials 10 5 (2020): 986-986. https://doi.org/10.3390/nano10050986. 10.3390/nano10050986 Marques, Sara S.; Ramos, Inês I.; Fernandes, Sara R.; Barreiros, Luisa; Lima, Sofia A. C.; Reis, Salette; Domingues, M. Rosário M.; Segundo, Marcela A.. "Insights on Ultrafiltration-Based Separation for the Purification and Quantification of Methotrexate in Nanocarriers". Molecules 25 8 (2020): 1879. http://dx.doi.org/10.3390/molecules25081879. 10.3390/molecules25081879 Coutinho, A.J.; Costa Lima, S.A.; Afonso, C.M.M.; Reis, S.. "Mucoadhesive and pH responsive fucoidan-chitosan nanoparticles for the oral delivery of methotrexate". International Journal of Biological Macromolecules 158 (2020): 180-188. http://www.scopus.com/inward/record.url?eid=2-s2.0-85084220190&partnerID=MN8TOARS. 10.1016/j.ijbiomac.2020.04.233 Ana Isabel Barbosa; Ana Joyce Coutinho; Sofia A. Costa Lima (corresponding author); Salette Reis. "Marine Polysaccharides in Pharmaceutical Applications: Fucoidan and Chitosan as Key Players in the Drug Delivery Match Field". Marine Drugs 17 12 (2019): 654-654. https://doi.org/10.3390/md17120654. Publicado • 10.3390/md17120654 Shakel, Zinaida; Nunes, Cláudia; Reis, Salette. "Development of a novel human stratum corneum model, as a tool in the optimization of drug formulations". International Journal of Pharmaceutics 569 (2019): 118571. http://dx.doi.org/10.1016/j.ijpharm.2019.118571. Publicado • 10.1016/j.ijpharm.2019.118571 Abderrazzaq Essaghraoui; Ahmed Belfkira; Bassou Hamdaoui; Cláudia Nunes; Sofia A. Costa Lima (corresponding author); Salette Reis. "Improved Dermal Delivery of Cyclosporine A Loaded in Solid Lipid Nanoparticles". Nanomaterials (2019): https://doi.org/10.3390/nano9091204. 10.3390/nano9091204 João C. Campos; Domingos C. Ferreira; Sofia Lima; Salette Reis; Paulo J. Costa. "Swellable polymeric particles for the local delivery of budesonide in oral mucositis". International Journal of Pharmaceutics 566 (2019): 126-140. https://doi.org/10.1016/j.ijpharm.2019.05.057. 10.1016/j.ijpharm.2019.05.057 Ana Isabel Barbosa; Sofia A. Costa Lima (corresponding author); Salette Reis. "Development of methotrexate loaded fucoidan/chitosan nanoparticles with anti-inflammatory potential and enhanced skin permeation". International Journal of Biological Macromolecules (2019): https://doi.org/10.1016/j.ijbiomac.2018.12.014. 10.1016/j.ijbiomac.2018.12.014 Barbosa, A.I.; Costa Lima, S.A. (corresponding author); Reis, S.. "Application of pH-responsive fucoidan/chitosan nanoparticles to improve oral quercetin delivery". Molecules 24 2 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85060092617&partnerID=MN8TOARS. 10.3390/molecules24020346 Lopes-De-Campos, D.; Pinto, R.M.; Costa Lima, S.A.; Santos, T.; Sarmento, B.; Nunes, C.; Reis, S.. "Delivering amoxicillin at the infection site-a rational design through lipid nanoparticles". International Journal of Nanomedicine 14 (2019): 2781-2795. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065589930&partnerID=MN8TOARS. 10.2147/IJN.S193992 Barbosa, A.I.; Fernandes, S.R.; Machado, S.; Sousa, P.; Sze, O.Y.; Silva, E.M.P.; Barreiros, L.; et al. "Fast monolith-based chromatographic method for determination of methotrexate in drug delivery studies". Microchemical Journal 148 (2019): 185-189. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065077944&partnerID=MN8TOARS. 10.1016/j.microc.2019.04.075 Chaves, L.L.; Silveri, A.; Vieira, A.C.C.; Ferreira, D.; Cristiano, M.C.; Paolino, D.; Di Marzio, L.; et al. "pH-responsive chitosan based hydrogels affect the release of dapsone: Design, set-up, and physicochemical characterization". International Journal of Biological Macromolecules 133 (2019): 1268-1279. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065421875&partnerID=MN8TOARS. 10.1016/j.ijbiomac.2019.04.178 Júlio, A.; Caparica, R.; Costa Lima, S.A.; Fernandes, A.S.; Rosado, C.; Prazeres, D.M.F.; Reis, S.; De Almeida, T.S.; Fonte, P.. "Ionic liquid-polymer nanoparticle hybrid systems as new tools to deliver poorly soluble drugs". Nanomaterials 9 8 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85074534554&partnerID=MN8TOARS. 10.3390/nano9081148 Júlio, A.; Costa Lima, S.A.; Reis, S.; Santos de Almeida, T.; Fonte, P.. "Development of ionic liquid-polymer nanoparticle hybrid systems for delivery of poorly soluble drugs". Journal of Drug Delivery Science and Technology (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85060944790&partnerID=MN8TOARS. 10.1016/j.jddst.2019.01.030 Araújo, D.; Alves, V.D.; Lima, S.A.C.; Reis, S.; Freitas, F.; Reis, M.A.M.. "Novel hydrogels based on yeast chitin-glucan complex: Characterization and safety assessment". International Journal of Biological Macromolecules (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85075984052&partnerID=MN8TOARS. 10.1016/j.ijbiomac.2019.11.141 Spirou SV; Costa Lima SA; Bouziotis P; Vranješ-Djuric S; Efthimiadou E¿; Laurenzana A; Barbosa AI; et al. "Recommendations for In Vitro and In Vivo Testing of Magnetic Nanoparticle Hyperthermia Combined with Radiation Therapy.". Nanomaterials (Basel, Switzerland) (2018): http://europepmc.org/abstract/med/29734795. 10.3390/nano8050306 Chaves LL; Costa Lima SA; Vieira ACC; Barreiros L; Segundo MA; Ferreira D; Sarmento B; Reis S. "Nanosystems as modulators of intestinal dapsone and clofazimine delivery.". Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (2018): http://europepmc.org/abstract/med/29864923. 10.1016/j.biopha.2018.04.195 Gouveia VM; Lopes-de-Araújo J; Costa Lima SA; Nunes C; Reis S. "Hyaluronic acid-conjugated pH-sensitive liposomes for targeted delivery of prednisolone on rheumatoid arthritis therapy.". Nanomedicine (London, England) (2018): http://europepmc.org/abstract/med/29790395. 10.2217/nnm-2017-0377 Alexandre C. C. Vieira; Luíse L. Chaves; Marina Pinheiro; Sofia A. Costa Lima; Domingos Ferreira; Bruno Sarmento; Salette Reis. "Mannosylated solid lipid nanoparticles for the selective delivery of rifampicin to macrophages". Artificial Cells, Nanomedicine, and Biotechnology (2018): https://doi.org/10.1080/21691401.2018.1434186. 10.1080/21691401.2018.1434186 Luíse L. Chaves; Sofia Lima; Alexandre C. C. Vieira; Domingos Ferreira; Bruno Sarmento; Salette Reis. "Overcoming clofazimine intrinsic toxicity: statistical modelling and characterization of solid lipid nanoparticles". Journal of The Royal Society Interface (2018): https://doi.org/10.1098/rsif.2017.0932. 10.1098/rsif.2017.0932 Moskvin, M.; Babic, M.; Reis, S.; Cruz, M.M.; Ferreira, L.P.; Carvalho, M.D.; Lima, S.A.C.; Horák, D.. "Biological evaluation of surface-modified magnetic nanoparticles as a platform for colon cancer cell theranostics". Colloids and Surfaces B: Biointerfaces 161 (2018): 35-41. http://www.scopus.com/inward/record.url?eid=2-s2.0-85032858139&partnerID=MN8TOARS. 10.1016/j.colsurfb.2017.10.034 Chaves, L.L.; Costa Lima, S.A.; Vieira, A.C.C.; Barreiros, L.; Segundo, M.A.; Ferreira, D.; Sarmento, B.; Reis, S.. "Development of PLGA nanoparticles loaded with clofazimine for oral delivery: Assessment of formulation variables and intestinal permeability". European Journal of Pharmaceutical Sciences 112 (2018): 28-37. http://www.scopus.com/inward/record.url?eid=2-s2.0-85033398806&partnerID=MN8TOARS. 10.1016/j.ejps.2017.11.004 Cavalcanti, S.M.T.; Nunes, C.; Costa Lima, S.A.; Soares-Sobrinho, J.L.; Reis, S.. "Optimization of nanostructured lipid carriers for Zidovudine delivery using a microwave-assisted production method". European Journal of Pharmaceutical Sciences 122 (2018): 22-30. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048987574&partnerID=MN8TOARS. 10.1016/j.ejps.2018.06.017 Machado, S.; Fernandes, S.R.; Chaves, L.L.; Lima, S.A.C.; Silva, E.M.P.; Barreiros, L.; Reis, S.; Segundo, M.A.. "Chromatographic method for the simultaneous quantification of dapsone and clofazimine in nanoformulations". Journal of Separation Science 41 17 (2018): 3382-3388. http://www.scopus.com/inward/record.url?eid=2-s2.0-85051109733&partnerID=MN8TOARS. 10.1002/jssc.201800427 Lima, Sofia; Vieira, A.C.C.; Chaves, L.L.; Pinheiro, S.; Pinto, S.; Pinheiro, M.; Lima, S.C.; et al. "Mucoadhesive chitosan-coated solid lipid nanoparticles for better management of tuberculosis.". Int J Pharm. 536 1 (2017): 478-485. http://www.scopus.com/inward/record.url?eid=2-s2.0-85037993500&partnerID=MN8TOARS. doi: 10.1016/j.ijpharm.2017.11.071 Sofia A. Costa Lima; André Gaspar; Salette Reis; Luísa Durães. "Multifunctional nanospheres for co-delivery of methotrexate and mild hyperthermia to colon cancer cells". Materials Science and Engineering: C 75 (2017): 1420-1426. https://doi.org/10.1016/j.msec.2017.03.049. 10.1016/j.msec.2017.03.049 Ana Rute Neves; Joana Fontes Queiroz; Sofia A. Costa Lima; Salette Reis. "Apo E-Functionalization of Solid Lipid Nanoparticles Enhances Brain Drug Delivery: Uptake Mechanism and Transport Pathways". Bioconjugate Chemistry 28 4 (2017): 995-1004. https://doi.org/10.1021/acs.bioconjchem.6b00705. 10.1021/acs.bioconjchem.6b00705 Gaspar, A.S.; Wagner, F.E.; Amaral, V.S.; Costa Lima, S.A.; Khomchenko, V.A.; Santos, J.G.; Costa, B.F.O.; Durães, L.. "Development of a biocompatible magnetic nanofluid by incorporating SPIONs in Amazonian oils". Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy 172 (2017): 135-146. http://www.scopus.com/inward/record.url?eid=2-s2.0-84963819416&partnerID=MN8TOARS. 10.1016/j.saa.2016.04.022 Chaves, L.L.; Costa Lima, S.A.; Vieira, A.C.; Barreiros, L.; Segundo, M.A.; Ferreira, D.; Sarmento, B.; Reis, S.. "PH-sensitive nanoparticles for improved oral delivery of dapsone: Risk assessment, design, optimization and characterization". Nanomedicine 12 16 (2017): 1975-1990. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026748544&partnerID=MN8TOARS. 10.2217/nnm-2017-0105 Ferreira, M.; Barreiros, L.; Segundo, M.A.; Torres, T.; Selores, M.; Reis, S.. "Topical co-delivery of methotrexate and etanercept using lipid nanoparticles: A targeted approach for psoriasis management". Colloids and Surfaces B: Biointerfaces 159 (2017): 23-29. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026661669&partnerID=MN8TOARS. 10.1016/j.colsurfb.2017.07.080 Cavalcanti, S.M.T.; Nunes, C.; Lima, S.A.C.; Soares-Sobrinho, J.L.; Reis, S.. "Multiple Lipid Nanoparticles (MLN), a New Generation of Lipid Nanoparticles for Drug Delivery Systems: Lamivudine-MLN Experimental Design". Pharmaceutical Research 34 6 (2017): 1204-1216. http://www.scopus.com/inward/record.url?eid=2-s2.0-85015624217&partnerID=MN8TOARS. 10.1007/s11095-017-2136-0 Silva, E.; Barreiros, L.; Segundo, M.A.; Costa Lima, S.A. (corresponding author); Reis, S.. "Cellular interactions of a lipid-based nanocarrier model with human keratinocytes: Unravelling transport mechanisms". Acta Biomaterialia 53 (2017): 439-449. http://www.scopus.com/inward/record.url?eid=2-s2.0-85010934600&partnerID=MN8TOARS. 10.1016/j.actbio.2017.01.057 Mara Ferreira; Elisabete Silva; Luísa Barreiros; Marcela A. Segundo; Sofia A. Costa Lima; Salette Reis. "Methotrexate loaded lipid nanoparticles for topical management of skin-related diseases: Design, characterization and skin permeation potential". International Journal of Pharmaceutics 512 1 (2016): 14-21. https://doi.org/10.1016/j.ijpharm.2016.08.008. 10.1016/j.ijpharm.2016.08.008 Segundo, Marcela A.; Abreu, Vera L. R. G.; Osorio, Marcelo V.; Nogueira, Sonia; Lin, Paul Kong Thoo; Cordeiro-da-Silva, Anabela; Lima, Sofia A. C.. "Development and validation of HPLC method with fluorometric detection for quantification of bisnaphthalimidopropyldiaminooctane in animal tissues following administration in polymeric nanoparticles". Journal of Pharmaceutical and Biomedical Analysis 120 (2016): 290-296. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000370585700038&KeyUID=WOS:000370585700038. 10.1016/j.jpba.2015.12.033 Neves, Ana Rute; Queiroz, Joana Fontes; Costa Lima, Sofia A.; Figueiredo, Francisco; Fernandes, Rui; Reis, Salette. "Cellular uptake and transcytosis of lipid-based nanoparticles across the intestinal barrier: Relevance for oral drug delivery". Journal of Colloid and Interface Science 463 (2016): 258-265. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000366961400032&KeyUID=WOS:000366961400032. 10.1016/j.jcis.2015.10.057 Gouveia, V; Lima, Sofia; Nunes, Cláudia; Reis, Salette. "Non-biologic nanodelivery therapies for rheumatoid arthritis". Journal of Biomedical Nanotechnology (2015): 10.1166/jbn.2015.2159 Sofia A. Costa Lima (corresponding author); Salette Reis. "Temperature-responsive polymeric nanospheres containing methotrexate and gold nanoparticles: A multi-drug system for theranostic in rheumatoid arthritis". Colloids and Surfaces B: Biointerfaces 133 (2015): 378-387. http://dx.doi.org/10.1016/j.colsurfb.2015.04.048. 10.1016/j.colsurfb.2015.04.048 Ferreira M; Chaves LL; Lima SA (corresponding author); Reis S. "Optimization of nanostructured lipid carriers loaded with methotrexate: a tool for inflammatory and cancer therapy.". (2015): http://europepmc.org/abstract/med/26169145. 10.1016/j.ijpharm.2015.07.013 Barros, D.; Lima, S.A.C. (corresponding author); Cordeiro-Da-Silva, A.. "Surface functionalization of polymeric nanospheres modulates macrophage activation: Relevance in Leishmaniasis therapy". Nanomedicine 10 3 (2015): 387-403. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923640156&partnerID=MN8TOARS. 10.2217/nnm.14.116 Costa Lima, S.A. (corresponding author); Silvestre, Ricardo; Barros, Daniela; Cunha, Joana; Dinis-Oliveira, R.; Cordeiro-da-Silva, Anabela. "Crucial CD8+ T-lymphocyte cytotoxic role in amphotericin B nanospheres efficacy against experimental visceral leishmaniasis". Nanomedicine: Nanotechnology, Biology and Medicine (2014): http://www.sciencedirect.com/science/article/pii/S1549963414000033#. 10.1016/j.nano.2013.12.013 Pinto, M.F.; Moura, C.C.; Nunes, C.; Segundo, M.A.; Costa Lima, S.A. (corresponding author); Reis, S.. "A new topical formulation for psoriasis: Development of methotrexate-loaded nanostructured lipid carriers". International Journal of Pharmaceutics 477 1-2 (2014): 519-526. http://www.scopus.com/inward/record.url?eid=2-s2.0-84911935101&partnerID=MN8TOARS. 10.1016/j.ijpharm.2014.10.067 Lima, Sofia. "Surface functionalization of polymeric nanospheres modulates macrophage activation – application in visceral leishmaniasis therapy.". (2014): 10.2217/NNM.14.116 Roussaki, M.; Hall, B.; Lima, S.C.; Da Silva, A.C.; Wilkinson, S.; Detsi, A.. "Synthesis and anti-parasitic activity of a novel quinolinone-chalcone series". Bioorganic and Medicinal Chemistry Letters 23 23 (2013): 6436-6441. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886946961&partnerID=MN8TOARS. 10.1016/j.bmcl.2013.09.047 Sofia A. Costa Lima. "Aurones: A Promising Heterocyclic Scaffold for the Development of Potent Antileishmanial Agents". International Journal of Medicinal Chemistry (2012): http://www.hindawi.com/journals/ijmc/2012/196921/. 10.1155/2012/196921 Mehdi, O.; Françoise, S.; Sofia, C.L.; Urs, G.; Kevin, Z.; Bernard, S.; Igor, S.; et al. "HDAC gene expression in pancreatic tumor cell lines following treatment with the HDAC inhibitors panobinostat (LBH589) and trichostatine (TSA)". Pancreatology 12 2 (2012): 146-155. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862163445&partnerID=MN8TOARS. 10.1016/j.pan.2012.02.013 Costa Lima, S.A. (corresponding author); Resende, M.; Silvestre, R.; Tavares, J.; Ouaissi, A.; Lin, P.K.T.; Cordeiro-Da-Silva, A.. "Characterization and evaluation of BNIPDaoct-loaded PLGA nanoparticles for visceral leishmaniasis: In vitro and in vivo studies". Nanomedicine 7 12 (2012): 1839-1849. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871263911&partnerID=MN8TOARS. 10.2217/nnm.12.74 Martins, S.; Costa-Lima, S.; Carneiro, T.; Cordeiro-Da-Silva, A.; Souto, E.B.; Ferreira, D.C.. "Solid lipid nanoparticles as intracellular drug transporters: An investigation of the uptake mechanism and pathway". International Journal of Pharmaceutics 430 1-2 (2012): 216-227. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860780308&partnerID=MN8TOARS. 10.1016/j.ijpharm.2012.03.032 Costa Lima, S.A. (corresponding author); Rodrigues, V.; Garrido, J.; Borges, F.; Kong Thoo Lin, P.; Cordeiro Da Silva, A.. "In vitro evaluation of bisnaphthalimidopropyl derivatives loaded into pegylated nanoparticles against Leishmania infantum protozoa". International Journal of Antimicrobial Agents 39 5 (2012): 424-430. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859430685&partnerID=MN8TOARS. 10.1016/j.ijantimicag.2012.01.003 Vilas-Boas, V.; Silva, R.; Gaio, A.R.; Martins, A.M.; Lima, S.C.; Cordeiro-da-Silva, A.; de Lourdes Bastos, M.; Remião, F.. "P-glycoprotein activity in human Caucasian male lymphocytes does not follow its increased expression during aging". Cytometry Part A 79 A 11 (2011): 912-919. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054897494&partnerID=MN8TOARS. 10.1002/cyto.a.21135 Silva, R.; Carmo, H.; Dinis-Oliveira, R.; Cordeiro-Da-Silva, A.; Lima, S.C.; Carvalho, F.; De Lourdes Bastos, M.; Remião, F.. "In vitro study of P-glycoprotein induction as an antidotal pathway to prevent cytotoxicity in Caco-2 cells". Archives of Toxicology 85 4 (2011): 315-326. http://www.scopus.com/inward/record.url?eid=2-s2.0-79954426149&partnerID=MN8TOARS. 10.1007/s00204-010-0587-8 Lin, P.K.T.; Hoskins, C.; Ouaissi, M.; Lima, S.C.; Cheng, W.P.; Loureirio, I.; Mas, E.; et al. "In vitro and in vivo anticancer activity of a novel nano-sized formulation based on self-assembling polymers against pancreatic cancer". Pharmaceutical Research 27 12 (2010): 2694-2703. http://www.scopus.com/inward/record.url?eid=2-s2.0-78651326311&partnerID=MN8TOARS. 10.1007/s11095-010-0268-6 Lima, S.A.C.; Tavares, J.; Gameiro, P.; de Castro, B.; Cordeiro-da-Silva, A.. "Flurazepam inhibits the P-glycoprotein transport function: An insight to revert multidrug-resistance phenotype". European Journal of Pharmacology 581 1-2 (2008): 30-36. http://www.scopus.com/inward/record.url?eid=2-s2.0-38549114108&partnerID=MN8TOARS. 10.1016/j.ejphar.2007.11.045 Lima, S.A.C.; Cordeiro-Da-Silva, A.; De Castro, B.; Gameiro, P.. "Benzodiazepine-mediated structural changes in the multidrug transporter P-glycoprotein: An intrinsic fluorescence quenching analysis". Journal of Membrane Biology 223 3 (2008): 117-125. http://www.scopus.com/inward/record.url?eid=2-s2.0-53849101372&partnerID=MN8TOARS. 10.1007/s00232-008-9117-5 Lima, S.A.C.; Cordeiro-da-Silva, A.; de Castro, B.; Gameiro, P.. "Sensitivity of P-glycoprotein tryptophan residues to benzodiazepines and ATP interaction". Biophysical Chemistry 125 1 (2007): 143-150. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750698584&partnerID=MN8TOARS. 10.1016/j.bpc.2006.07.006 Lima, S.A.C.; Cordeiro-Da-Silva, A.; Gameiro, P.; De Castro, B.. "A method for functional mouse MDR3 P-glycoprotein reconstitution in Escherichia coli lipids". Analytical Biochemistry 338 2 (2005): 350-353. http://www.scopus.com/inward/record.url?eid=2-s2.0-14644420801&partnerID=MN8TOARS. 10.1016/j.ab.2004.10.022 Lima, S.A.C.; Raposo, M.F.J.; Castro, P.M.L.; Morais, R.M.. "Biodegradation of p-chlorophenol by a microalgae consortium". Water Research 38 1 (2004): 97-102. http://www.scopus.com/inward/record.url?eid=2-s2.0-0345714784&partnerID=MN8TOARS. 10.1016/j.watres.2003.09.005 Lima, S.A.C.; Castro, P.M.L.; Morais, R.. "Biodegradation of p-nitrophenol by microalgae". Journal of Applied Phycology 15 2-3 (2003): 137-142. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038042051&partnerID=MN8TOARS. 10.1023/A:1023877420364
Capítulo de livro	Ana Isabel Barbosa; Raquel Costa; Tânia Moniz; Costa Lima, S.A.; Salette Reis. "Nanostrategies for skin delivery: tools for skin inflammatory diseases topical therapy". In The Road from Nanomedicine to Precision Medicine, editado por Shaker A Mousa; Raj Bawa; Gerald F Aude. Jenny Stanford, 2022. Em revisão Ana Isabel Barbosa; Filipa Serrasqueiro; Tânia Moniz; Costa Lima, S.A.; Salette Reis. "Marine polysaccharides for skin drug delivery: hydrogels and microneedles solutions". editado por Sougata Jana. Singapure: Springer Nature, 2022. Publicado Costa Lima, S A; Reis, Salette. "Nanotechnological Approaches in Drug Absorption through Skin Topical Delivery". In Nanoparticles in the Life Sciences and Biomedicine. Pan Stanford Publishing, 2018. Publicado Chaves, L L; Vieira, A.C.; Domingos, F; Sarmento, B; Reis, Salette; Costa Lima, S A. "Nanocarriers as a Strategy for Oral Bioavailability Improvement of Poorly Water-Soluble Drugs". In Nanoparticles in the Life Sciences and Biomedicine. Pan Stanford Publishing, 2018. Publicado
Edição de livro	Adriano Bordalo e Sá; Begoña Pérez-Cabezas; Azevedo, Luísa; Costa Lima, Sofia A.. One Health – Uma Saúde Um contributo da Universidade. Porto: UP Press. 2024. Publicado • Editor
Edição de número de revista	Costa Lima, S A; Reis, Salette. "Polymeric Carriers for Biomedical and Nanomedicine Application". Polymers (2020): https://www.mdpi.com/journal/polymers/special_issues/carrier_nanomedicine. Publicado • Editor convidado
Livro	Polymeric Carriers for Biomedical and Nanomedicine Application. 2021. Publicado • Editor
Poster em conferência	Ferreira, Sónia ; Grenho, Liliana; Maria Helena Fernandes; Costa Lima, Sofia A.. "Development and characterization of nanoparticles with curcumin for intracanalar treatment". Trabalho apresentado em Congresso Sociedade Portuguesa de Endodontia, 2024. Shakel, Zinaida; Reis, Salette; Goril Flaten; Costa Lima, Sofia A.. "Skin permeation studies: comparing ex vivo Human Skin, porcine skin, and PVPA models". Trabalho apresentado em European Society for Dermatological Research (ESDR), 2024. Beatriz Silva; Daniela Oliveira; Reis, Salette; Costa Lima, Sofia A.. "Nanoencapsulation of Vitamin K3 for pet food fortification". Trabalho apresentado em IJUP 2024, 2024. Renata Basto; Reis, Salette; Lima, Sofia. "Polymeric nanoparticles loaded with an antioxidant defense to combat Androgenetic Alopecia". Trabalho apresentado em XXVII Encontro Luso-Galego de Química, 2023. Shakel, Zinaida; Reis, Salette. "Unlocking the potential of carrageenan-based hydrogels: skin delivery with antioxidant and anti-inflammatory properties". Trabalho apresentado em XXIVII Encontro Luso-Galego, 2023. Joana Fernandes; Carolina Barroso; Aires, Tiago; António Fonseca; Lima, Sofia; Maia, Margarida R. G.; Ana Rita Cabrita. "Evaluation of alternative marine sources as protein ingredients in pet food". Trabalho apresentado em 48th World Small Animal Veterinary Association Congress and the 28th FECAVA Eurocongress (WSAVA 2023), 2023. Daniela Oliveira; Beatriz Silva; Nuno Saraiva; Paula Gomes; Lima, Sofia; Reis, Salette. "Encapsulation of nutrients for food fortification using solid lipid nanopartiles". Trabalho apresentado em 12th International Colloid Conference, 2023. Gabriel Machado; Reis, Salette; Lima, Sofia. "Obtention and Characterization of a Polyphenol enriched extract from Olive pomace". Trabalho apresentado em Portuguese Young Chemistry Meeting, 2023. Daniela Oliveira; Beatriz Silva; Paula Gomes; Lima, Sofia; Reis, Salette. "Development and characterization of solid lipid nanoparticles formulations in nutrients delivery for animal feed fortification". Trabalho apresentado em Portuguese Young Chemistry Meeting, 2023. Renata Basto; Zinaida Sakel; Aikaterini Spanou; Ana Isabel Barbosa; Claudia Nunes; Reis, Salette; Costa Lima, S A. "Nanoplatforms drive slow down skin ageing". Trabalho apresentado em XXVI Encontro Luso-Galego de Química, 2022. Joana Fernandes; Costa Lima, S A; Maia, Margarida R. G.; Ana Rita Cabrita. "Marine sources in dog feeding: nutritive value and palatability of squid meal and shrimp hydrolysate". Trabalho apresentado em Workshop PDCA 2022, 2022. Ana Isabel Barbosa; Spanou, Aikaterini ; Reis, Salette; Lima, Sofia. "Genistein-loaded nanostrategies for skin anti-aging". Trabalho apresentado em 15º IJUP, 2022. Ana Catarina Dias; Basto, Renata; Ana Isabel Barbosa; Lima, Sofia; Reis, Salette. "Cutaneous drug delivery systems to control skin inflammation". Trabalho apresentado em 15º IJUP, 2022. Andreia Marinho; Catarina Leal Seabra; Lima, Sofia; Claudia Nunes; Reis, Salette. "Anti-inflammatory effect of naringin delivered in lipid nanoparticles". Trabalho apresentado em NALS-Nanomaterials Applied to Life Sciences 2022, 2022. "Essential oil-enriched marine hydrogels for stratum corneum permeation enhancement". Trabalho apresentado em ChemBioGels 2021, 2021. "Topical delivery of niacinamide to skin using hybrid nanogels enhances photoprotection effect". Trabalho apresentado em ChemBioGels 2021, 2021. "Nutritive value and palatability of microalgae species in dog feeding". Trabalho apresentado em EAAP Annual Meeting 2021, 2021. "Synthesis of sugar-coated marine polymeric nanosystems for topical delivery of bioactive agents". Trabalho apresentado em 14th IJUP, 2021. Suellen Morais; Costa Lima, S A; Salette Reis; Claudia Nunes; Célia Sousa. "Iron-based Nanostructures Encapsulated in Lipid Nanoparticles as a Multifunctional Nanocarriers for doxorubicin controlled delivery". Trabalho apresentado em NALS 2020 - Nanomaterials Applied to Life Sciences, 2020. Tânia Moniz; Sedef Kaplan; Lima, Sofia; Salette Reis. "Chemical characterization of the PVPAsc model: the effect of surfactants and different pH on barrier permeability". Trabalho apresentado em Skin & Formulation Network, 2019. Simone Stefani; Ana Isabel Barbosa; Tânia Moniz; Sofia A. Costa Lima; Salette Reis. "Optimization of a nanoformulation for skin delivery: the influence of structure and composition". Trabalho apresentado em Skin & Formulation Network, 2019. 10.1109/cise.2009.5365231 Maria Inês Silva; Ana Isabel Barbosa; Lima, Sofia; Salette Reis. "A nanotechnological approach for the topical delivery of cyclosporine A". Trabalho apresentado em Skin & Formulation Network, Bath, 2019. Tânia Moniz; Simone Stefani; Ana Isabel Barbosa; Lima, Sofia; Salette Reis. "In vitro skin models: a novel lipid-based human stratum corneum mimetic model for the optimization of skin drug formulations". Trabalho apresentado em Skin Forum, Reims, 2019. Diana Araújo; Vitor Alves; Lima, Sofia; Filomena Freitas; Elvira Fortunato; Maria A. M. Reis. "Transdermal delivery systems based on natural polymeric biomaterials". Trabalho apresentado em Ciencia 2019, 2019. Ana Isabel Barbosa; Lima, Sofia; Salette Reis. "In vitro skin cellular model: a tool to unravel transport mechanisms and bioavailability". Trabalho apresentado em Advanced Summer School – Interrogations at the Biointerface, 2019. João Campos; Domingos Ferreira; Lima, Sofia; Salette Reis; Paulo Costa. "Local budesonide delivery using polymeric nanoparticles for oral mucositis management". Trabalho apresentado em 6th Nano Today Conference, 2019. Lima, Sofia; Ana Isabel Barbosa; Tânia Moniz; Cláudia Nunes; Salette Reis. "A novel human stratum corneum mimetic model, as a tool in the optimization of skin drug formulations". Trabalho apresentado em ETPN / NanoMed Europe, 2019. Mariana Romanholo; Ana Isabel Barbosa; Diana Resende; Lima, Sofia; Emília Sousa; Madalena Pinto; Salette Reis. "Marine nature as a source for cancer therapy: xanthone loaded fucoidan/chitosan nanoparticles". Trabalho apresentado em 12th IJUP, 2019. João Campos; Domingos Ferreira; Lima, Sofia; Salette Reis; Paulo Costa. "Development of budesonide polymeric mucoadhesive particles for the local management of oral mucositis". Trabalho apresentado em SPLC-CRS Santiago Compostela, 2019. Sara Marques; Inês Ramos; Sara Fernandes; Luísa Barreiros; Lima, Sofia; Salette Reis; Maria Domingues; Marcela A. Segundo. "Exploiting ultrafiltration for purification and characterization of drug-nanocarriers". Trabalho apresentado em Euroanalysis 2019, 2019. Zinaide Shakel; Claudia Nunes; Lima, Sofia; Salette Reis. "In Vitro Skin Models As A Tool In The Optimization Of Drug Formulation.". Trabalho apresentado em SFNano 2018, Montepellier, 2018. Sara Marques; Inês Ramos; Luísa Barreiros; Lima, Sofia; Salette Reis; Maria R. Domingues; Marcela A. Segundo. "Immunopurification of nanoparticles under lab-on-valve format Immunopurification of nanoparticles under lab-on-valve format.". Trabalho apresentado em Flow Analysis and Capillary Electrophoresis, Hradec Kralove, 2018. Sara Marques; Inês Ramos; Luísa Barreiros; Lima, Sofia; Salette Reis; Maria R. Domingues; Marcela A. Segundo. "Evaluation of encapsulation efficiency in methotrexate-loaded nanoparticles using separative methods". Trabalho apresentado em Analita 2018: 9th Meeting of the Analytical Chemistry Division, 2018. Sândia Machado; Sara Fernandes; Luíse Chaves; Sofia A. Costa Lima; Eduarda Silva; Luísa Barreiros; Salette Reis; Marcela A. Segundo. "Simultaneous determination of Dapsone and Clofazimine in nanoformulations by HPLC". Trabalho apresentado em Analita 2018: 9th Meeting of the Analytical Chemistry Division, 2018. 10.1109/rsete.2011.5966191 Joana Cardoso; Ana Isabel Barbosa; Lima, Sofia; Salette Reis. "Fucoidan/ Chitosan nanoparticles: the influence of type and amount of polysaccharides". Trabalho apresentado em 11st IJUP, 2018. Daniela Lopes-de-Campos; Rita M. Pinto; Catarina Seabra; Lima, Sofia; Cristina Martins; Cláudia Nunes; Salette Reis. "Amoxicillin-loaded lipid nanoparticles: towards a therapeutic approach for Helicobacter pylori infections". Trabalho apresentado em NanoBio&Med2017, 2017. Miguel Horta; Rita Leal; Lima, Sofia; Célia Sousa; J. P. Araújo; Salette Reis; Cláudia Nunes. "Paclitaxel loaded hybrid magnetic-lipid nanoparticles as a novel approach for cancer therapy". Trabalho apresentado em 1st BioBrillouin Meeting, 2017. Lima, Sofia; Salette Reis. "Co-delivery of gold nanoparticles and methotrexate in polymeric nanospheres for photothermal therapy". Trabalho apresentado em 1st BioBrillouin Meeting, 2017. Joana Cardoso; Ana Isabel Barbosa; Lima, Sofia; Salette Reis. "Development and characterization of Fucoidan/ Chitosan pH sensitive nanoparticles". Trabalho apresentado em 10th IJUP, 2017. Beatriz Costa; A. S. Gaspar; P. H. C. Santos; F. E. Wagner; Lima, Sofia; O. B. Ribeiro; L. Durães. "Development of biocompabible magnetic nanofluids for biomedical applications". Trabalho apresentado em 2nd International Conference on “Multifunctional Materials and their Applications”, 2017. Ana Isabel Barbosa; Lima, Sofia; Carlos Afonso; Salette Reis. "Optimization and characterization Chitosan/Fucoidan pH sensitive nanoparticles for delivery of methotrexate". Trabalho apresentado em XXII Encontro Luso-Galego de Química, 2016. Liliana Pereira; M. M. Cruz; M. L. Oliveira; S. G. Mendo; A. F. Alves; Salette Reis; Lima, Sofia; M. Godinho; M. D. Carvalho. "Decorated nanoparticles of magnetic hyperthermia.". Trabalho apresentado em 11th Inorganic Chemistry Conference, Portuguese Society of Chemistry, 2016. Luíse L. Chaves; Alexandre Vieira; Lima, Sofia; Domingos Ferreira; Bruno Sarmento; Salette Reis. "Solid lipid nanoparticles as strategy to improve clofazimine intestinal absorption: design, characterization and in vitro cytotoxicity studies". Trabalho apresentado em 7th International Congress Nanotechnology in Biology & Medicine - BioNanoMed, 2016. Lima, Sofia; Salette Reis. "Magnetic nanoparticle – cancer cell interactions: noninvasive assessment". Trabalho apresentado em RADIOMAG Annual Meeting, 2015. A. S. Gaspar; F. E. Wagner; V. S. Amaral; Lima, Sofia; J.G. Santos; B. F. O. Costa; L. Durães. "Development of a magnetic nanofluid by incorporating SPIONs in Amazonian oils". Trabalho apresentado em XXXIX CSI, 2015. P. Tibaldo; L. L. Chaves; Lima, Sofia; Salette Reis. "Optimization and characterization of methotrexate-loaded polymeric nanoparticles: a Box-Behnken design approach". Trabalho apresentado em 8th IJUP 2015, 2015. Mara Ferreira; Lima, Sofia; Salette Reis. "Optimization and characterization of lipid-based nanoparticles for topical therapy of psoriasis". Trabalho apresentado em NanoPT 2015, 2015. Mara Ferreira; Lima, Sofia; Salette Reis. "Optimization and development of nanostructure lipid carriers for topical therapy of psoriasis". Trabalho apresentado em Luso Galego 2014, 2014. Lima, Sofia; Salette Reis. "Theranostic nanospheres for localized photothermal therapy of Rheumatoid Arthritis.". Trabalho apresentado em ETP-Nanomedicine Annual Meeting 2014, 2014. Daniela Barros; Lima, Sofia; Anabela Cordeiro-da-Silva. "Surface functionalization of polymeric nanospheres modulates macrophage activation – application in visceral leishmaniasis therapy". Trabalho apresentado em Bioimaging 2014, 2014. Maria Pinto; Lima, Sofia; Salette Reis. "Methotrexate-loaded NLCs for psoriasis topical therapy: optimization, production and characterization". Trabalho apresentado em ANM 2014, 2014. Lima, Sofia; Salette Reis. "Methotrexate-loaded polymeric nanospheres containing Gold nanoparticles for localized photothermal therapy of Rheumatoid Arthritis". Trabalho apresentado em NanoBio-Europe, 2014. Lima, Sofia; Salette Reis. "Quantification of methotrexate released from drug delivery systems". Trabalho apresentado em Simpósio SPQ-Analítica 2014, 2014. Lima, Sofia; M. T. Baltazar; R. J. Dinis-Oliveira; Anabela Cordeiro-da-Silva. "Therapeutic efficacy and safety of BNIPDaoct-loaded PLGA nanoparticles for the treatment of visceral leishmaniasis". Trabalho apresentado em 7th IJUP 2014, 2014. Lima, Sofia; Salette Reis. "Preparation and characterization of polymeric nanospheres for rheumatoid arthritis treatment.". Trabalho apresentado em NanofolNanodiara Meeting - Nanoparticles for early Diagnostics of inflammatory diseases, 2013. A. R. Neves; Lima, Sofia; J. L. C. Lima; Salette Reis. "Nanoimaging of resveratrol-loaded lipid nanoparticles during caco-2 cell uptake". Trabalho apresentado em International Symposium in Applied Bioimaging 2013, 2013. M. V. Osório; S. Nogueira; Marcela A. Segundo; V. L. R. G. Abreu; Anabela Cordeiro-da-Silva; Lima, Sofia. "Assessment of an anti-Leishmania compound loaded on PLGA nanoparticles - in vitro and in vivo studies". Trabalho apresentado em 6th IJUP 2013, 2013. S. Nogueira; D. Barros; Anabela Cordeiro-da-Silva; Lima, Sofia. "Unraveling the mechanism of action of BNIPDiaminooctane on Leishmania infantum parasites – target identification and development of resistant strain.". Trabalho apresentado em 6th IJUP 2013, 2013. Daniela Barros; Anabela Cordeiro-da-Silva; Lima, Sofia. "Immunotherapeutic potential of mannosylated nanoparticles". Trabalho apresentado em XXXVIII Annual Meeting of the Portuguese Society of Immunology, 2012. M. Ouaissi; F. Silvy; Lima, Sofia; B. Sastre; I. Sielezneff; Anabela Cordeiro-da-Silva; D. Lombardo; E. Mas; A. Ouaissi. "HDAC gene expression in pancreatic tumor cell lines submitted to the probinostat or trichostatin HDAC Inhibitors". Trabalho apresentado em ESSR 2012 47th Annual Congress, 2012. Daniela Barros; Anabela Cordeiro-da-Silva; Lima, Sofia. "Mannosylated nanoparticles for targeted delivery of amphotericin B towards visceral leishmaniasis". Trabalho apresentado em 3rd I3S scientific meeting, 2012. Patrícia Varela; P. K. T. Lin; Lima, Sofia; Anabela Cordeiro-da-Silva. "Drug screening of bisnaphthalimidopropyl derivatives on Trypanosoma brucei.". Trabalho apresentado em 3rd I3S scientific meeting, 2012. Daniela Barros; Anabela Cordeiro-da-Silva; Lima, Sofia. "Active targeting of macrophages by mannosylated nanoparticles loaded with amphotericin B towards visceral leishmaniasis therapy.". Trabalho apresentado em Colloids and Nanomedicine, 2012. Patrícia Varela; P. K. T. Lin; Anabela Cordeiro-da-Silva; Lima, Sofia. "In vitro screening of bisnaphthalimidopropyl derivatives on Trypanosoma brucei". Trabalho apresentado em British Society for Parasitology Spring Meeting 2012, 2012. M. Ouaissi; F. Silvy; Lima, Sofia; B. Sastre; I. Sielezneff; Anabela Cordeiro-da-Silva; D. Lombardo; E. Mas; A. Ouaissi. "Etude de l'efficacité panobinostat LBH 589 sur l’inhibition de la croissance des lignées cellulaires cancéreuses pancréatiques et la corrélation au niveau d’expression des HDAC". Trabalho apresentado em Journees Francophones d’Hepato-gastroenterologie et d’Oncologie Digestive 2012, 2012. Patrícia Varela; P. K. T. Lin; Anabela Cordeiro-da-Silva; Lima, Sofia. "Drug screening of bisnaphthalimidopropyl derivatives on Trypanosoma brucei". Trabalho apresentado em 5th IJUP’12, 2012. Daniela Barros; Lima, Sofia; Anabela Cordeiro-da-Silva. "Development and optimisation of targeted drug delivery systems towards visceral leishmaniasis". Trabalho apresentado em 5th IJUP’12, 2012. M. V. Osório; S. Nogueira; Marcela A. Segundo; V. L. R. G. Abreu; Anabela Cordeiro-da-Silva; Lima, Sofia. "Evaluation of anti-Leishmania compound released from polymeric nanoparticles". Trabalho apresentado em 5th IJUP’12, 2012. Marcela A. Segundo; V. L. R. G. Abreu; M. V. Osório; S. Nogueira; Anabela Cordeiro-da-Silva; Lima, Sofia. "Fluorimetric determination of bisnaphthalimidopropyldiaaminooctane by liquid chromatography using a monolithic column". Trabalho apresentado em 7º Encontro Nacional de Cromatografia, 2012. A. L. Robalo; J. A. Pereira; M. Resende; D, Moreira; J. Cunha; Lima, Sofia; Anabela Cordeiro-da-Silva. "Activation of IL-27p28 gene transcription on antigen presenting cells infected with Leishmania infantum". Trabalho apresentado em XXXVII SPI Annual Meeting, 2011. M. Ouaissi; F. Sylvi; Lima, Sofia; B. Sastre; I. Sielezneff; Anabela Cordeiro-da-Silva; E. Mas; A. Ouaissi. "Characterization of the anti-pancreatic tumor cell effect induced by LBH589 and its relation to HDAC encoding genes expression". Trabalho apresentado em Porto Cancer Meeting, 2011. K. Prousis; M. Roussaki; B. Hall; S. Wilkinson; Lima, Sofia; Anabela Cordeiro-da-Silva. "Novel antiparasitic agents based on the quinolinone heterocyclic scaffold". Trabalho apresentado em COST annual meeting, 2011. Lima, Sofia; V. Rodrigues; J. Garrido; F. Borges; P. K. T. Lin; Anabela Cordeiro-da-Silva. "Pegylated nanoparticles for encapsulation of bisnaphthalimidopropyl derivatives against Leishmania infantum". Trabalho apresentado em Trends in Nanotechnology, 2010. Lima, Sofia; M. Roussaki; S. Sampaio; A. Detsi; Anabela Cordeiro-da-Silva. "Determinação da actividade anti-Leishmania de compostos heterocíclicos por citometria de fluxo". Trabalho apresentado em XIV Congresso Português de Parasitologia, 2010. M. Roussaki; K. Prousis; Lima, Sofia; Anabela Cordeiro-da-Silva; A. Detsi. "Natural Product Analogues with anti - Leishmania infantum activity". Trabalho apresentado em 14th Hellenic Symposium on Medicinal Chemistry, 2010. S. Sampaio; Lima, Sofia; A. Detsi; Anabela Cordeiro-da-Silva. "Bioactivity of flavonoids against Leishmania infantum determined by flow cytometry". Trabalho apresentado em 3º Encontro de Jovens Investigadores da Universidade do Porto, 2010. Lima, Sofia; P. K. T. Lin; Anabela Cordeiro-da-Silva. "In vitro evaluation of bisnaphthalimidopropyl-derivatives loaded PLGA nanoparticles on Leishmania infected cells". Trabalho apresentado em 18th Conference on Inorganic Chemistry, 2009. Lima, Sofia; P. K. T. Lin. "Encapsulation of bisnaphthalimidopropyl derivatives, two novel anti-Leishmania drugs, in biodegradable PLA and PLGA nanoparticles". Trabalho apresentado em Nanomedicine 2008, 2008. R. Silva; Anabela Cordeiro-da-Silva; Lima, Sofia; F. Carvalho; M. L. Bastos; H. Carmo; F. Remião. "Effect of P-Glycoprotein inducers on its expression and activity in Caco-2 cells". Trabalho apresentado em 45th Eurotox Congress, 2008. Lima, Sofia; Anabela Cordeiro-da-Silva; B. de Castro; P. Gameiro. "Citometria de fluxo: um método para quantificar e identificar inibidores da P-glicoproteína". Trabalho apresentado em 6º Encontro Nacional de Química Analítica, 2006. Lima, Sofia; Anabela Cordeiro-da-Silva; B. de Castro; P. Gameiro. "Conformational changes of P-glycoprotein induced by drug - and nucleotide- binding". Trabalho apresentado em 4º Encontro do REQUIMTE, 2006. Lima, Sofia; Anabela Cordeiro-da-Silva; B. de Castro; P. Gameiro. "Intrinsic fluorescence of membrane transport proteins – sensitivity of Trp residues to binding of drugs". Trabalho apresentado em 1st European Conference on Chemistry for Life Sciences, 2005. Lima, Sofia; Anabela Cordeiro-da-Silva; B. de Castro; P. Gameiro. "A Resonance Energy Transfer study of the Rifampicin and RifampicinSV interaction with the multidrug transporter P-glycoprotein". Trabalho apresentado em 3rd Portuguese-Spanish Biophysics Congress, 2004. Lima, Sofia; Anabela Cordeiro-da-Silva; P. Gameiro; B. de Castro. "Intrinsic tryptophan fluorescence study of the interaction of benzodiazepines with P-glycoprotein.". Trabalho apresentado em Transporters 2004 – International Symposium on Membrane Transport and Transporters, 2004. Lima, Sofia; Anabela Cordeiro-da-Silva; P. Gameiro; B. de Castro. "Evaluation of the structure and function of the reconstituted P-glycoprotein multidrug transporter". Trabalho apresentado em 3º Encontro do REQUIMTE, 2004. Lima, Sofia; Anabela Cordeiro-da-Silva; P. Gameiro; B. de Castro. "Determinação do coeficiente de partição rifampicina/lipossomas por espectrofotometria derivative". Trabalho apresentado em 3º Encontro Nacional de Química Analítica, Escola Superior e Biotecnologia da Universidade Católica Portuguesa, 2003. Sofia A. Costa Lima; Forgac, Michael; P. Gameiro; B. de Castro. "Reconstitution of ATPase activity in proteoliposomes of mouse MDR3 P-glycoprotein.". Trabalho apresentado em XVII European Colloid and Interface Society Conference, 2003. 10.1158/1535-7163.targ-15-a124 Lima, Sofia; Anabela Cordeiro-da-Silva; P. Gameiro; B. de Castro. "Purificação da P-glicoproteína (MDR3) funcional a partir de células de Pichia pastoris". Trabalho apresentado em 1º Congresso da Sociedade Portuguesa de Ciências Farmacêuticas, 2003. Lima, Sofia; P. M. L. Castro; R. M. Morais. "Degradation of and p-nitrophenol by a cyanobacteria consortium". Trabalho apresentado em 10th European Congress in Biotechnology, 2001. Lima, Sofia; R. H. Pires; F. Tavaria; F. X. Malcata. "Characterisation of bacterial isolates from Serra da Estrela Cheese via analysis of their electrophoretic protein profiles.". Trabalho apresentado em BIOTEC'98 – IV Congresso Ibérico de Biotecnologia e I Encontro Ibero-Americano de Biotecnologia, 1998.
Tese / Dissertação	Martins, Patrícia Varela Oliveira,1988-. "Drug screening of Bisnaphthalimidopropyl derivatives on Trypanosoma brucei". Mestrado, 2012. http://hdl.handle.net/10451/8390. Costa Lima, S A. "Evaluation of the structure and function of P-glycoprotein, membrane transporter, in the presence of benzodiazepines and tuberculostatics". Doutoramento, Universidade do Porto Faculdade de Ciências, 2007. Costa Lima, S A. "Production of oral vaccines in Solanum tuberosum L.". Mestrado, De Montfort University, 1999.

Propriedade Intelectual

Pedido provisório de patente

2021. "Colorimetric nanosensor for SARS-CoV-2 (NPAT404/2020)".
Divulgado

Atividades

Apresentação oral de trabalho

	Título da apresentação	Nome do evento Anfitrião (Local do evento)
2024/11/15	Lipid Nanoparticles in Action: Powering Hyaluronic Acid Production in Skin Cells	XXVI Encontro Galego-Portugués de Química (Vigo, Espanha)
2024/11/15	Breaking bAD: using chemistry, biophysics and biotechnology to unburden Atopic Dermatitis	XXVIII Encontro Galego-Portugués de Química (Vigo, Espanha)
2024/09/09	Unveiling the effects of shrimp hydrolysate as a dietary supplement in healthy adult Beagle dogs	XIII Jornadas de Alimentação Animal
2024/02/15	A sea of nano-possibilities: marine hybrid hydrogels combined with nanoparticles to treat Atopic Dermatitis	NALS - Nanomaterials Applied to Life Sciences 2024 (Granada, Espanha)
2023/11/23	Comparative analysis of kappa- and iota-carrageenan hydrogels for effective skin delivery	International Conference on Nanotechnology Research and Innovation Universidade de Aveiro (Aveiro, Portugal)
2023/11/23	One nano-step closer to improve Atopic Dermatitis symptoms	XXVII Encontro Luso-Galego de Química (Porto, Portugal)
2023/11/23	Olive pomace extract as a multi-functional bioresource for macrophage polarity modulation	XXVII Encontro Luso-Galego de Química (Porto, Portugal)
2023/10/13	Effects of shrimp hydrolysate powder in the general health of adult dogs and palatability of diets	Annual Workshop of Doctoral Programme in Animal Science (Vila do Conde, Portugal)
2023/05/29	Application of nanotechnoloy to overcome the skin barrier	International Conference Recent Achievements in Nanotechnology University of Bialystok (Bialystok, Polónia)
2023/05/10	Olive pomace valorisation by obtention of a bioactive compounds enriched extract	16h IJUP University of Porto (Porto, Portugal)
2023/02/08	Breaking the Skin Barrier through Advanced Nanoplatforms	LAQV-REQUIMTE Webinar 2023 LAQV-REQUIMTE (Portugal)
2022/11/16	Searching for the chemistry that works: formulating hydrogels and nanogels towards atopic dermatitis therapy	XXIII Encontro Galego-Português de Quimica Facultad de Química Universidad de Santiago de Compostela (Santiago de Compostela, Espanha)
2022/11/16	Characterization of kappa- and iota- carrageenans-based hydrogels as potential vehicles in skin delivery	XXII Encontro Luso-Galego de Química Facultad de Química Universidad de Santiago de Compostela (Santiago de Compostela, Espanha)
2022/09/04	Marine protein sources in dog feeding: nutritive value and palatability of squid meal and shrimp hydrolysate	73rd EAAP Annual Meeting European Federation of Animal Science (Porto, Portugal)
2022/06/30	Evaluation of transdermal permeation of phthalate angico gum nanoparticles containing nevirapine in microneedles	InnovDelivery 2022 Universidade Lusófona (Lisboa, Portugal)
2022/06/30	Betamethasone-loaded hybrid hydrogels to manage atopic dermatitis	InnovDelivery 2022 Universidade Lusófona (Lisboa, Portugal)
2022/06/30	Exploiting smart delivery systems to slow down skin ageing	InnovDelivery 2022 Universidade Lusófona (Lisboa, Portugal)
2022/06/30	Quercetin-loaded lipid nanoparticles with improved antioxidant capacity potential for skin applications	InnovDelivery 2022 Universidade Lusófona (Lisboa, Portugal)
2022/06/03	Synchrotron-based Infrared Microspectroscopy of nanoplatforms and skin: unveiling molecular interactions	Biophysics Festival 2022 Universidade de Aveiro (Aveiro, Portugal)
2022/05/17	Profiling the effect of skin-targeted nanoplatforms through synchroton FTIR microspectroscopy	6º Encontro de Biotecnologia Microbiana e Farmacêutica Universidade do Porto, Faculdade de Farmácia (Porto, Portugal)
2021/11/08	Human stratum corneum lipid-based mimetic model: a tool to study drugs' permeability	3rd E-Meeting on Polymer Science & Biomaterials (Polybiomat-2021)
2021/10/20	Nanoparticles to prevent SARS-CoV-2 transmission	Modtissimo - Scientific Developments Regarding Protection Against Pathogens such as Sars-Cov-2 (online conference) CITEVE (Portugal)
2021/09/17	Breaking the barrier: N-acetyl-cysteine-loaded nanoparticles as a strategy to disrupt bacterial biofilms	ESB 2021 – 31ST Conference of the European Society for Biomaterials. European Society for Biomaterials. (Espanha)
2021/06/17	Understanding Cell-Nanoparticle Interaction: a new gateway to disease therapeutics	XVII Congress of Iberian Society of Flow Citometry Instituto Português de Oncologia do Porto
2021/05/06	Optimization of topical delivery for niacinamide using hydrogels and transethosomes	14th IJUP University of Porto
2021/02/22	Nanotechnological approaches to STOP SARS-CoV-2 transmission	JorTec DCM – Jornadas Tecnológicas do Departamento de Ciência dos Materiais Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa, online conference
2020/11/18	Overcoming the skin barrier: in vitro models and nanostrategies to enhance drug absorption	Webinar @ Lunch University of Florence
2020	Quercetin-loaded Hydrogels for Skin Ageing and Inflammation	NanoPT
2019/11/22	Fucoidan/chitosan nanoparticles: delivery system for synthetized xanthone towards a in cancer therapy	Simpósio de Investigação da Faculdade de Farmácia da Universidade do Porto, Porto Faculdade de Farmácia da Universidade do Porto, Porto (por, Portugal)
2019/06/12	Unravelling drug’s permeation and transport mechanisms of lipid nanocarriers using in vitro skin models	EUFEPS Open Forum (Bonn, Alemanha)
2018/11/22	Topical delivery of cyclosporine A using lipid nanoparticles	XXIV Encontro Luso-Galego Faculty of Science, University of Porto (Porto, Portugal)
2018/11/22	Fighting bacterial resistance: a novel nanosystem for N-acetyl-cysteine (NAC) delivery	XXIV Encontro Luso-Galego University of Porto (po, Portugal)
2018/11/21	Targeting and killing the ever-challenge ulcer bug	XXIV Encontro Luso-Galego Faculty of Science, University of Porto (Porto, Portugal)
2018/02/12	Topical delivery of methotrexate using Fucoidan/Chitosan nanoparticles	11st IJUP University of Porto (Porto, Portugal)
2018/02/08	Development and characterization of pH sensitive fucoidan-chitosan nanoparticles for oral delivery of methotrexate	11st IJUP University of Porto (po, Portugal)
2018/02/08	Vitamin A encapsulation in lipid nanoparticles for food applications: development, characterization and stability	11st IJUP University of Porto (Porto, Portugal)
2018/02/08	Cyclosporine A-loaded solid lipid nanoparticles for topical application	11st IJUP Universidade do Porto (Porto, Portugal)
2018/02/08	Preparation and characterization of nanostructured lipid carriers for methotrexate delivery into breast-cancer cells – a hyperthermia approach.	11st IJUP Universidade do Porto (Porto, Portugal)
2017/12/07	Chromatographicc analysis of biological samples using monolithic columns.	10th Encontro Nacional de Cromatografia (Bragança, Portugal)
2017/11/16	Nanoplatforms as diagnostic and therapeutic tools.	Conference + Bioquímica Faculty of Science and Technology, Lisbon (Lisboa, Portugal)
2017/11/16	Application of lipid nanoparticles containing vitamin A in food: development and physico-chemical stability studies.	XXIII Encontro Galego-Português de Quimica (Ferrol, Espanha)
2017/02/09	Chitosan/Fucoidan pH sensitive nanoparticles for delivery of methotrexate	10th IJUP-Encontro Investigação Jovem da Universidade do Porto 2017 University of Porto (po, Portugal)
2017/02/08	Development of Cyclosporine A-loaded lipid nanoparticles (LN) formulations for topical application	10th IJUP-Encontro Investigação Jovem da Universidade do Porto 2017 University of Porto (Porto, Portugal)
2017/02/03	Cyclosporine A-loaded solid lipid nanoparticles versus nanostructured lipid carriers for dermal applications	NanoPT 2017 (Porto, Portugal)
2017/02/02	Amoxicillin-loaded lipid nanoparticles: a novel approach to treat Helicobacter pylori infections	NanoPT 2017 (por, Portugal)
2016/11/10	Development and optimization of amoxicillin-loaded lipid nanoparticles as a therapeutic approach for Helicobacter pylori infections	XXII Encontro Luso-Galego de Química (Bragança, Portugal)
2016/11/09	Development and validation of HPLC method for quantification of dapsone and clofazimine loaded nanoparticles upon bioavailability assessment	XXII Encontro Luso-Galego de Química (Bragança, Portugal)
2016/03/06	Challenges and Advances in Oral Drug Delivery using Lipid-based Nanoparticles.	Pharmaceutica 2016 (Madrid, Espanha)
2016/02/18	Nanostructured Lipid Carriers: a new approach for Psoriasis topical therapy	NanoPT 2016 (Braga, Portugal)
2015/11/20	Identification of keratinocytes’ interaction with nanostructured lipid carriers	II Congresso Internacional de Saúde Gaia-Porto Escola Superior de Saúde (Vila Nova de Gaia, Portugal)
2015/05/14	Application of box-behnken design to optimize methotrexate loaded nanostructured lipid nanoparticles	8th IJUP- Encontro Investigação Jovem da Universidade do Porto 2015 Universidade do Porto (Porto, Portugal)
2015/04/18	Why and how to assess the toxicity at the cell scale of new nanoprobes?	COST TD1402 - RADIOMAG Annual Meeting COST TD1402 (Lisboa, Portugal)
2015/02/09	pH sensitive liposomes loading prednisolone for the treatment of rheumatoid arthritis.	NanoPT 2015 (Porto, Portugal)
2015/02/09	New insights in the development of solid lipid nanoparticles for active brain-targeted drug delivery	NanoPT 2015 (Porto, Portugal)
2015/02/09	Temperature-responsive polymeric nanospheres containing methotrexate and gold nanoparticles: a multidrug system for theranostics in rheumatoid arthritis	NanoPT 2015 (Porto, Portugal)
2014/12/02	Targeted pH sensitive liposomes for the treatment of rheumatoid arthritis	Luso-Galego (Porto, Portugal)
2014/12/02	Solid lipid nanoparticles as a vehicle for brain-targetted drug delivery	Luso-Galego (Porto, Portugal)
2014/11/06	Methotrexate-loaded lipid-based nanoparticles for topical therapy of psoriasis: Optimization and characterization	Jornadas Bioengenharia FEUP (Porto, Portugal)
2014/10/12	A theranostic approach using methotrexate-loaded polymeric nanospheres containing Gold nanoparticles for Rheumatoid Arthritis.	Annual Meeting COST ActionTD1004 COST TD1004 (Istambul, Turquia)
2014/06/21	Development of Innovative Therapeutic Approaches for Rare Diseases	Training Seminar (Riga, Letónia)
2013/12/12	Validated chromatographic method for fluorimetric determination of an anti-Leishmania compound in mice tissues	8º Encontro Nacional de Cromatografia
2013/06/06	Crucial CD8+ T-lymphocyte cytotoxic role in amphotericin B nanospheres efficacy against experimental visceral leishmaniasis	Infection and Immunity Unit Meeting IBMC (Porto, Portugal)
2012/11/20	Mannosylated nanoparticles for targeted delivery of amphotericin B towards visceral leishmaniasis	XVI Congresso Português de Parasitologia (Lisboa, Portugal)
2012/11/20	Drug screening of bisnaphthalimidopropyl derivatives on Trypanosoma brucei	XVI Congresso Português de Parasitologia (Lisboa, Portugal)
2012/09/14	The role of bisnaphthalimidopropyl derivatives to control trypanosomatid neglected infections	COST Annual Meeting COST CM801 (Chania, Grécia)
2012/05/16	Avaliação da atividade in vitro e in vivo do BNIPDaoct encapsulado em nanopartículas poliméricas no parasita Leishmania infantum	Jornadas de Parasitologia II, Escola Superior de Tecnologia da Saúde do Porto Escola Superior de Tecnologia da Saúde do Porto (Vila Nova de Gaia, Portugal)
2011/11/14	In vitro evaluation of BNIPDaoct encapsulated on polymeric nanoparticles on Leishmania infantum parasite	VI Congresso Científico da Associação de Estudantes da Faculdade de Farmácia da Universidade do Porto Associação de Estudantes da Faculdade de Farmácia da Universidade do Porto (Porto, Portugal)
2011/10/06	Improvement of in vitro and in vivo antileishmanial activities of Bisnaphthalimidopropyldiaaminooctane by encapsulation in poly(D,L-lactide-co-glycolide nanoparticles	III Congress of the Portuguese Society of Pharmaceutical Sciences and IX Spanish-Portuguese Conference on Controlled Drug Delivery (Porto, Portugal)
2011/03/13	The use of poly(lactic-co-glycolic acid) nanoparticles to encapsulate amphotericin B towards visceral leishmaniasis	12th Drug Design and Development (Heidelberg, Alemanha)
2011/01/10	Nanotechnology as a tool towards trypanosomatids and pancreatic cancer chemotherapies	Invited Seminar University of Vigo (Vigo, Espanha)
2010/09/20	Development of new therapeutics based on the identification of molecular drug targets and on drug screening against the mammalian stage of the parasite.	3rd Scientific Division Day of the Infection and Immunity Unit IBMC (Porto, Portugal)
2010/05/16	Nanotechnology as a tool towards trypanosomiasis and leishmaniasis chemotherapies	2nd Joint Expert Meeting among Working Groups 1/2/3/4 and MC Meeting of the COST Action CM0801 COST Action CM0801 (Siena, Itália)
2009/05/10	Effect of bisnaphthalimidopropyl polyamine derivatives against experimental Leishmania infantum infection by cytosolic SIR2 related protein 1	Joint Expert Meeting between Working Groups 1 and 3 of the COST Action CM0801 COST Action CM0801 (Sófia, Bulgária)
2001/07/19	Degradation of p-chlorophenol and p-nitrophenol by a microalgae community	10th European Congress in Biotechnology (Madrid, Espanha)
1998/07/15	Characterisation of bacterial isolates from Serra da Estrela Cheese via analysis of their electrophorectic protein profiles	BIOTEC'98 (Guimarães, Portugal)

Orientação

	Título / Tema Papel desempenhado	Curso (Tipo) Instituição / Organização
2023/02/01 - Atual	Alternative protein sources in pet food - a nanotechnological approach Orientador	Licenciatura em Bioquímica (Licenciatura/Bacharelato) Universidade do Porto Faculdade de Ciências, Portugal
2022/10/01 - Atual	Design of a targeted drug delivery system to reshape the perifollicular microenvironment in androgenetic alopecia Coorientador	Doctoral Programme on Cellular and Molecular Biotechnology Applied to Health Sciences (BiotechHealth) (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/09/01 - Atual	Synthesis of polyphenol-conjugated lipid nanoparticles for macrophage modulation Coorientador	Mestrado em Química Farmacêutica (Mestrado) Universidade do Porto Faculdade de Farmácia, Portugal
2021/10/01 - Atual	Design of a hyaluronic acid delivery system to slow down skin ageing Coorientador	Doctoral Program in Pharmaceutical Sciences (Doutoramento) Universidade do Porto Faculdade de Farmácia, Portugal REQUIMTE LAQV Porto, Portugal
2021/05/01 - Atual	Tackling microbial resistance: transdermal delivery of antibiotic drugs as Ionic Liquids and Organic Salts using nanostructured biomaterials Coorientador	Programa Doutoral em Química Sustentável (Doutoramento) Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/10 - Atual	Natural hydrogels as an Intracanal Therapeutic Tool - combination of antimicrobial and photodynamic therapies to prevent reinfections Orientador de Sónia Ferreira	Programa Doutoral Ciências Biológicas Aplicadas à Saúde (Doutoramento) Instituto Universitário de Ciências da Saúde, Portugal
2020/02/10 - Atual	Controlled modulation of macrophages by sugar-functionalized nanoparticles. Coorientador de Mariana Romanholo	Mestrado em Ciências Farmacêuticas (Licenciatura/Bacharelato) Universidade do Porto Faculdade de Farmácia, Portugal
2020/10 - 2024/10/25	Development and evaluation of berberine nanoparticles as an antimicrobial tool in endodontic irrigation Orientador de Célia Marques	Programa Doutoral Ciências Biológicas Aplicadas à Saúde (Doutoramento) Instituto Universitário de Ciências da Saúde, Portugal
2020/01/01 - 2024/10/11	Marine-based nanotechnological approaches for dermatitis in developing countries Coorientador de Ana Isabel Barbosa	Programa Doutoral BiotechHealth (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/10/01 - 2023/09/30	Novel functional ingredients in pet food - a multifactorial study of alternative diets for dogs Coorientador	Programa Doutoral SANFEED (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/01/02 - 2022/12/19	Improving health and growth in gilthead seabream (Sparus aurata) through fortified nutrition: discovering new nutraceuticals from marine bio-refineries Coorientador de Bruno Reis	Programa Doutoral SANFEED (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/03/01 - 2021/10/07	Alginate-derived microneedle devices for transdermal delivery of rivastigmine - application in skin mimetic model Coorientador	Mestrado Integrado em Bioegenharia (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/03/01 - 2021/09/22	Synthesis of sugar-coated marine polymeric nanosystems for topical delivery of bioactive agents Orientador de Filipa Serrasqueiro	Mestrado em Química Farmacêutica (Mestrado) Universidade do Porto Faculdade de Farmácia, Portugal
2020/10/02 - 2021/03/29	Optimization of topical delivery of niacinamide using hydrogels and transethosomes for anti-ageing Orientador	Mestrado Integrado em Bioengenharia (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/02/02 - 2019/09/02	Development and Characterization of Lipid Nanoparticles for Topical Drug Administration Coorientador de Simone Stefani	Chemistry and Pharmaceutical Technology Master (Mestrado) Università degli Studi di Modena e Reggio Emilia Biblioteca Universitaria Umanistica, Itália
2019/02/14 - 2019/07/17	Application of gold nanoparticles in fingermarks detection – optimization of detection process Orientador de Bruna Faria	Licenciatura em Ciências Laboratoriais Forenses (Licenciatura/Bacharelato) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2018/03/10 - 2018/07/26	Development of gold nanoparticles in fingermarks detection Orientador de Application of gold nanoparticles in fingermarks detection	Licenciatura em Ciências Laboratoriais Forenses (Licenciatura/Bacharelato) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2017/09/02 - 2018/07/20	Lipid-based nanocarriers for food applications: strategies to maximize bioactive compounds’ bioavailability and their safety evaluation Coorientador de Daniela Resende	Bioeengenharia (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2017/09/06 - 2018/02/26	Cyclosporine A-loaded solid lipid nanoparticles for topical application Orientador de Maria Inês Silva	Mestrado Integrado em Ciências Farmacêuticas (Licenciatura/Bacharelato) Universidade do Porto Faculdade de Farmácia, Portugal
2017/12/01 - 2017/12/31	Hidrogéis híbridos - desenvolvimento de uma terapia tópica para a psoríase Coorientador de Mafalda Patrício	Programa Doutoral em Ciências Farmacêuticas (Doutoramento) Universidade do Porto Faculdade de Farmácia, Portugal
2016/10/02 - 2017/11/06	In vitro skin models as a tool in the optimization of drug formulation Orientador de Zinaida Shakel	Bioquímica (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal
2016/09/10 - 2017/07/20	Delivery of methotrexate using fucoidan/chitosan pH sensitive nanoparticles Coorientador de Ana Isabel Ferreira Barbosa	Química Farmacêutica (Mestrado) Universidade do Porto Faculdade de Farmácia, Portugal
2014/10/10 - 2015/07/16	NLC keratinocytes’ uptake mechanism Orientador de Elisabete Silva	Anatomo-pathology Technologist (Licenciatura/Bacharelato) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2014/09/04 - 2015/07/14	Nanostructured Lipid Carriers: a new approach for Psoriasis dermal therapy Orientador de Mara Ferreira	Biomedical Engineering Master (Mestrado)
2014 - 2014	Application of lipid nanoparticles for the delivery of methotrexate for dermal treatment of psoriasis Orientador de Maria Filipa Sanches Pinto	Bioengenharia (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2011/09/14 - 2013/11/26	Study of the Erlotinib (Tarceva) anticancer activity on liposomes Coorientador de Rita Vidal	Mestrado em Tecnologia Farmacêutica (Mestrado) Universidade do Porto Faculdade de Farmácia, Portugal
2013/02/08 - 2013/07/10	Drug screening in Leishmania promastigotes Coorientador de Melissa Raboni	Mestrado integrado em Ciências Farmacêuticas (Licenciatura/Bacharelato) Universidade do Porto Faculdade de Farmácia, Portugal
2011/10/02 - 2012/11/29	Drug screening of the bisnaphthilimidopropil derivatives on Trypanosoma brucei Orientador de Patrícia Varela Martins	Cellular Biology and Biotechnology (Mestrado) Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
2011/09/15 - 2012/10/26	Mannosylated nanoparticles for targeted delivery of amphotericin B towards visceral leishmaniasis Orientador de Daniela Barros	Biochemistry (Mestrado)
2012/02/07 - 2012/09/18	Drug target identification in Leishmania Orientador de Sónia Nogueira	Mestrado Integrado em Ciências Farmacêuticas (Licenciatura/Bacharelato) Universidade do Porto Faculdade de Farmácia, Portugal
2010/10/10 - 2011/06/08	Development and characterisation of paromomycin nanoparticles towards cutaneous leishmaniasis Orientador de Raquel Carneiro	Licenciatura em Biologia (Licenciatura/Bacharelato) Universidade do Porto Faculdade de Ciências, Portugal
2009/09/12 - 2010/06/04	Development and characterisation of bisnaphthalimidopropyl polyamine derivatives nanoparticles towards Leishmania infantum protozoa Coorientador de Susana Sampaio	Biology (Licenciatura/Bacharelato) Universidade do Porto Faculdade de Ciências, Portugal
2008/09/15 - 2010/01/07	Nanoparticles as drug delivery systems towards leishmaniasis: the effect of PEGylation Coorientador de Vasco Rodrigues	Biochemistry (Mestrado)
2007/10/01 - 2008/07/25	Characterization and optimization of poly(D,L-lactide-co-glycolide nanoparticles against Leishmania Coorientador de João Pedro Silva	Biochemistry (Licenciatura/Bacharelato) Universidade do Porto Faculdade de Ciências, Portugal
2007/10/02 - 2008/06/25	Development and characterization of poly-lactic acid nanoparticles towards Leishmania protozoa Coorientador de João Barbosa	Biochemistry (Licenciatura/Bacharelato) Universidade do Porto Faculdade de Ciências, Portugal
2002/09/14 - 2003/06/22	Drug partition determination in DMPC and DMPG liposomes Coorientador de Susana Silva	Chemistry (Outra) Universidade do Porto Faculdade de Ciências, Portugal
2001/09/20 - 2002/06/20	Aromatic compounds degradation by Chlorella vulgaris Coorientador de Maria João Saraiva	Microbiology (Licenciatura/Bacharelato) Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2001/09/20 - 2002/06/20	Aromatic compounds degradation by Chlorella vulgaris Coorientador de Mónica Silva	Microbiology (Licenciatura/Bacharelato) Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal

Organização de evento

	Nome do evento Tipo de evento (Tipo de participação)	Instituição / Organização
2024/11/04 - Atual	"One Health - Uma Saúde um contributo da universidade" book presentation at the University of Porto Rectory for the One Health International Day celebration. (2024/11/04) Outro (Membro da Comissão Organizadora)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/09/05 - Atual	One Health Talks (2023/10/23) Mesa-redonda (Membro da Comissão Organizadora)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - Atual	Universidade Júnior, program of Porto University in the project: À descoberta da nanotecnologia: aplicações na saúde e na alimentação (2019/07)	Universidade do Porto, Portugal
2017 - Atual	Universidade Júnior, program of Porto University in the project: À descoberta da nanotecnologia: aplicações na saúde e na alimentação (2017)
2011 - Atual	Workshop on New antiparasitic and anticancer drugs, funded by the ERA-NET New Indigo network (2011) Oficina (workshop) (Membro da Comissão Organizadora)	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2023/04/02 - 2023/11/04	Organização d "Expo One Health" (2023/11/02 - 2023/11/04) Exposição (Membro da Comissão Organizadora)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/09/13 - 2023/09/15	Annual Meeting NetSkinModels COST Action - Porto (2023/09/13 - 2023/09/15) Encontro	NetSkinModels COST Action, Áustria
2022/01/17 - 2022/01/21	Winter School on Membrane Biophysics: Impact of Lipids on Health, Disease and Therapy (3rd edition) (2022/01/17) Oficina (workshop) (Coorganizador)	Universidade do Porto Faculdade de Farmácia, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/06/12 - 2019/06/14	Advanced course on "Protein-ligand interactions: From theory to practice" (2019) Outro (Membro da Comissão Organizadora)	Universidade do Porto Faculdade de Farmácia, Portugal
2019/05/21 - 2019/05/24	Advanced course in "In vitro models of biological barriers for Health Sciences Applications" (2019) Outro (Membro da Comissão Organizadora)	Universidade do Porto Faculdade de Farmácia, Portugal
2018/07/02 - 2018/07/13	Universidade Júnior, program of Porto University in the project: À descoberta da nanotecnologia: aplicações na saúde e na alimentação (2018/07/02 - 2018/07/13) Oficina (workshop) (Presidente da Comissão Organizadora)	Universidade do Porto Faculdade de Farmácia, Portugal
2018/06/25 - 2018/06/29	Summer School on Membrane Biophysics: Impact of Lipids on Health, Disease and Therapy (2nd edition) (2018/06/25) Oficina (workshop) (Membro da Comissão Organizadora)	Universidade do Porto Faculdade de Farmácia, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/07/24 - 2017/07/28	Summer school on Membrane Biophysics: Impact of Lipids on Health, Disease and Therapy (2017/07/24) Oficina (workshop) (Membro da Comissão Organizadora)	Universidade do Porto Faculdade de Farmácia, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1998 - 1998	Jornadas de Microbiologia (1998) Simpósio (Membro da Comissão Organizadora)	Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal

Participação em evento

	Descrição da atividade Tipo de evento	Nome do evento Instituição / Organização
2024/11/16 - Atual	Workshop Doctoral Program in Animal Science 2024	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/10/15 - Atual	Workshop Doctoral Programme in Animal Science 2023	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/06/21 - Atual	Annual Workshop of Doctoral Program BiotechHealth 2023	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/09/15 - Atual	Workshop Doctoral Programme in Animal Science 2022 Oficina (workshop)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024/11/03 - 2024/11/08	Webinar entitled "Phytotherapy in cosmetics and therapeutics" within 2nd edition of the Advanced Doctoral Course "Topical and Transdermal Delivery". Oficina (workshop)	Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/04/05 - 2023/04/07	Webinar Organ and Tissue Engineering Oficina (workshop)	Université Paris-Saclay, França
2023/02/14 - 2023/02/18	Annual Meeting NetSkinModels COST Action - Bratislava, Slovakia Outro

Júri de grau académico

	Tema Tipo de participação	Nome do candidato (Tipo de grau) Instituição / Organização
2024/07/29	Oncostatin M: a multifaceted cytokine able to modulate inflammation Arguente principal	Anabela Ferreira Gonçalves (Doutoramento) Universidade do Minho, Portugal
2024/07/15	Development of an Immunomodulatory and ProAngiogenic Hydrogel to Advance the Healing of Chronic Wounds Arguente principal	Rita Gomes (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024/06/28	Cryobiophysics: Structure-Function-Property-Design Interplay of Polysaccharides in Crystal Binding Arguente principal	Bruno Miguel Soares Guerreiro (Doutoramento) Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/10/11	Exploring Thermoresponsive Chitosan – Pluronic® F-127 hydrogels for antimicrobial peptide release Arguente principal	Maria Carolina Antunes Matias (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2023/10/06	Production of Lipid Nanoparticles for Topical Administration of Flavonoids Vogal	Raquel Pinho Costa (Doutoramento) Universidade do Porto Faculdade de Ciências, Portugal
2023/05/11	SYNTHESIS AND CHARACTERIZATION OF IONIC LIQUIDS AND EVALUATION OF THEIR APPLICABILITY IN NEW PHARMACEUTICAL FORMULATIONS Presidente do júri	Rita Alexandra Mourato dos Reis Caparica (Doutoramento) Universidad de Alcalá, Espanha
2022/11/20	Development of an in vitro model of mucinous tumours Arguente principal	Ana Luísa Benavente (Mestrado) Universidade Nova de Lisboa Departamento de Química, Portugal
2022/10/20	Unveiling membrane dependent mechanism of action of molecules with anticancer activity Arguente principal	Daniela Oliveira (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2022/10/03	Establishment of an Experimental Protocol for Assessing the Transport of Nanoparticles in Breast Cancer Spheroids Arguente principal	Marta Isabel Miguel de Miranda e Amaral de Avelar (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/09/29	Development of porous microneedles: a novel approach to collect biomarkers for organ-on-a-chip monitoring Arguente principal	Renata Maia (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/06/03	APLICAÇÃO DE BIOPOLIMERO MODIFICADO DE GOMA DO ANGICO EM SISTEMAS DE LIBERAÇÃO: UMA ABORDAGEM UTILIZANDO MICROAGULHAS Arguente principal	Thaisa Cardoso de Oliveira (Doutoramento) Universidade Federal de Pernambuco, Brasil
2022/02/24	Pharmaceutical Ionic Liquids as an Effective Treatment against Mycobacterium Tuberculosis Arguente principal	Hugo Araújo (Mestrado) Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/01/27	Optimization of nanoparticles for the release of icilin in rheumatic diseases Arguente principal	Diana Sousa (Mestrado) Universidade do Minho Centro de Engenharia Biológica, Portugal
2021/02	Fabrication of a Yeast Microcapsule Platform for Bone Tissue Regeneration Arguente principal	Patrícia Gaspar de Oliveira (Mestrado) Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
2020/11/12	After the antibiotic era: effect of Nanostructured Lipid Carriers against Helicobacter pylori biofilms Arguente principal	Ana Sofia Ferreira Leite de Pinho (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/05/11	Lipid nanoparticles biocompatibility and cellular uptake in a 3D human lung model Arguente principal	Marina Barroso Pereira Pinheiro (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2020	Development of Neurotherapeutic Polyplexes for Oxidative Stress in Ischemic Stroke Arguente principal	Joana Filipa Ferreira Moreira (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/07/11	Bioengineering a 3D heterotypic tumor model to study the dynamics of endothelial cells recruitment and growth Arguente principal	Sara Chaves (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/10/15	Establishment of tricultures in microfluidic platforms Arguente principal	Miguel Guilherme Linhas Simões (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/07/20	Lipid-based nanocarriers for food applications: strategies to maximize bioactive compounds’ bioavailability and their safety evaluation Orientador	Daniela Resende (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2017/11/06	In vitro skin models as a tool in the optimization of drug formulation Orientador	Zinaida Shakel (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal
2017/10/12	Polymeric-based nanoparticles targeting the CCR5 co-receptor as an innovative approach for the delivery of antiretroviral compounds Arguente principal	Catarina Coutinho (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/10/12	Trimethyl-Chitosan-based Polyplexes for Neurotrophin Mimicking in Brain Ischaemia Arguente principal	Simão Pedro Barbosa Teixeira (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/07/21	Delivery of methotrexate using Fucoidan/Chitosan pH sensitive nanoparticles Orientador	Ana Isabel Barbosa (Mestrado) Universidade do Porto Faculdade de Farmácia, Portugal
2017/07/05	Nanostructured lipid carriers as a promising drug delivery system for streptomycin Arguente	Sara Pinheiro (Outro) Universidade do Porto Faculdade de Farmácia, Portugal
2017/06/02	New Technologies technologies for the improvement of leprosy multidrug therapy: a quality by design approach Vogal	Luíse Lopes Chaves (Doutoramento) Universidade do Porto Faculdade de Farmácia, Portugal
2016/11/13	Antiparasitic potential of natural marine compounds Arguente principal	Gisela Almeida Castro (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal
2015/12/11	Protein-based nanodevices for therapeutic applications Arguente principal	Ana Isabel Loureiro (Doutoramento) Universidade do Minho Escola de Ciências, Portugal
2015/10/06	Nanoparticle Delivery System for Bone Regeneration Arguente principal	Joana Nave (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2015/07/14	Nanostructured Lipid Carriers: a new approach for Psoriasis dermal therapy Orientador	Mara Ferreira (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2014/12/27	MicroRNA modulation incombination with chemotherapeutic drugs as a novel therapeutic strategy for pancreatic cancer Arguente principal	Marta Daniela Passadouro Caetano (Doutoramento) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/07/15	Development of multifunctional nanoparticles for targeted therapy and imaging of rheumatoid arthritis Arguente principal	Catarina Moura (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2012/11/29	Drug screening of the bisnaphthilimidopropil derivatives on Trypanosoma brucei Orientador	Patrícia Varela Martins (Mestrado) Universidade de Lisboa Faculdade de Ciências, Portugal
2012/10/26	Mannosylated nanoparticles for targeted delivery of amphotericin B towards visceral leishmaniasis Orientador	Daniela Barros (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal
2010/05/12	Leishmania spp infection model optimization for drug discovery purposes Arguente principal	Maria Helena Azevedo Teixeira de Andrade (Mestrado) Universidade do Porto Faculdade de Farmácia, Portugal
2010/01/07	Nanoparticles as drug delivery systems towards leishmaniasis: the effect of PEGylation Orientador	Vasco Rodrigues (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal

Arbitragem científica em conferência

	Nome da conferência	Local da conferência
2022/04/04 - 2022/04/06	7th World Congress on Recent Advances in Nanotechnology	Lisbon

Arbitragem científica em revista

	Nome da revista (ISSN)	Editora
2023/02/06 - Atual	Advanced Therapeutics
2018/10/25 - Atual	Immunotherapy International
2018/06/02 - Atual	Biochimica et Biophysica Acta (BBA) - Reviews on Cancer (0304-419X)	Elsevier
2018/04/02 - Atual	ACS Applied Materials & Interfaces
2018/02/04 - Atual	Journal of Pharmaceutics (2090-7818)	Hindawi (International Scholarly Research Network)
2018/02/02 - Atual	Marine Drugs	MDPI
2017/04/10 - Atual	Polymers (2073-4360)	MDPI AG
2017/03/20 - Atual	Nanomaterials and Nanotechnology (1847-9804)	SAGE Publications
2017/03/12 - Atual	Journal of Advanced Research (2090-1232)	Elsevier
2017/03/02 - Atual	Scientific Reports (2045-2322)	Springer Science and Business Media LLC
2017/02/02 - Atual	Molecules (1420-3049)	MDPI AG
2017/01/29 - Atual	Journal of the Science of Food and Agriculture (1097-0010)	Wiley (John Wiley & Sons)
2016/06/03 - Atual	Current Drug Delivery (1567-2018)	Bentham Science
2016/05/02 - Atual	Chemistry and Physics of Lipids (0009-3084)	Elsevier
2016/04/10 - Atual	Journal of Liposome Research (1532-2394)	Informa UK (Taylor & Francis)
2016/04/10 - Atual	Nanomaterials (2079-4991)	MDPI AG
2016/03/10 - Atual	Journal of Clinical Dermatology & Therapy
2016/03/05 - Atual	ACS Biomaterials Science & Engineering (2373-9878)	American Chemical Society
2015/04/02 - Atual	Drug Development and Industrial Pharmacy (1520-5762)	Informa UK (Taylor & Francis)
2015/02/10 - Atual	Acta Biomaterialia (1742-7061)	Elsevier
2015/02/10 - Atual	Nanomedicine (1748-6963)	Future Medicine
2014/09/04 - Atual	Biomaterials (0142-9612)	Elsevier
2013/04/10 - Atual	International Journal of Nanomedicine (1178-2013)	Dove Medical Press
2011/04/14 - Atual	Parasitology International (1383-5769)	Elsevier
2010/02/10 - Atual	Colloids and Surfaces B Biointerfaces (0927-7765)	Elsevier

Comissão de avaliação

	Descrição da atividade Tipo de assessoria	Instituição / Organização	Entidade financiadora
2024/11/11 - Atual	Chairnan of the jury of the probatory year exams for the Doctoral Program in Animal Science of the student Adriana Oliveira.	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/11/16 - Atual	Member of the jury of the probatory year exams for the Doctoral Program in Animal Science of the student Daniela Leal.	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/07/01 - Atual	Member of the evaluation panel of doctoral projects presented by 1st year students of the Doctoral Program BiotechHealth.	Universidade do Porto Faculdade de Farmácia, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/03 - Atual	Grant Reviewer Avaliador	National Science Centre Poland , Polónia
2019/07/01 - Atual	Member of the evaluation panel of doctoral projects presented by 1st year students of the Doctoral Program BiotechHealth.	Universidade do Porto Faculdade de Farmácia, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - Atual	Grant Reviewer Avaliador	Graduated Women in Science, Estados Unidos
2019 - Atual	Grant Reviewer Avaliador	The Israel Science Foundation, Israel
2017 - Atual	Grant Reviewer Avaliador	Université de Bordeaux, França
2014 - Atual	Evaluator of Trans-Domain COST Action Proposal Call Avaliador	European Commission, Bélgica	European Cooperation in Science and Technology
2010/02/01 - Atual	Member of the panel on the Pluridisciplinar projects 2010 of Porto University Avaliador	Universidade do Porto, Portugal	Banco Santander Totta
2024/07/01 - 2024/09/30	Grant reviewer for ANI - National Invocation Agency
2023/05/10 - 2023/07/10	Grant reviewer for HORIZON-HLTH - RIA Avaliador	European Commission, Bélgica
2017/05/20 - 2018/03/05	Grant Reviewer for European Commission H2020 projects Avaliador	European Commission, Bélgica	European Commission

Curso / Disciplina lecionado

	Disciplina	Curso (Tipo)	Instituição / Organização
2020/05/12 - Atual	Nanostrategies for skin delivery: application of in vitro models for drug absorption	Advanced Course “Bionanoparticles: challenges and therapeutic opportunities” (Outros)	Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2019/06/19 - Atual	Standard operating procedures (SOPs): theory	Advanced course on Protein-ligand interactions: From theory to practice (Outros)	Universidade do Porto Faculdade de Farmácia, Portugal
2019/06/19 - Atual	Experimental protocols and standard operating procedures: practice	Advanced course on Protein-ligand interactions: From theory to practice (Outros)	Universidade do Porto Faculdade de Farmácia, Portugal
2019/06/18 - Atual	Hands-on training: Ligand binding immunoassays	Advanced course on Protein-ligand interactions: From theory to practice (Outros)	Universidade do Porto Faculdade de Farmácia, Portugal
2019/06/17 - Atual	Ligand binding immunoassays: theory	Advanced course on Protein-ligand interactions: From theory to practice (Outros)	Universidade do Porto Faculdade de Farmácia, Portugal
2019/05/29 - Atual	Nanomedicine-based strategies to beat cancer	Cancer therapy: from basic research to clinic (Pós-Graduação)	Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2019/05/24 - Atual	Hands-on training: Franz diffusion cells	Advanced course on In vitro models of biological barriers for Health Sciences Applications (Outros)	Universidade do Porto Faculdade de Farmácia, Portugal
2019/05/23 - Atual	Skin: practical aspects	Advanced course on In vitro models of biological barriers for Health Sciences Applications (Outros)	Universidade do Porto Faculdade de Farmácia, Portugal
2016/06/02 - Atual	Multifunctional nanoparticles for cancer magnetic hyperthermia therapy	Advanced course on Bionanoparticles: challenges and therapeutic opportunities (Pós-Graduação)	Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2014/05/28 - Atual	Multifunctional nanomedicine platforms for Cancer Therapeutics	Bionanotechnology for diagnosis and therapy of cancer (Pós-Graduação)	Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2024/02/05 - 2024/06/30	Química Orgânica e Biológica	Licenciatura em Bioengenharia (Licenciatura)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/09/15 - 2024/01/31	Fundamentos da Química e da Biofísica	Mestrado Integrado em Medicina	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/02/12 - 2023/06/30	Química Orgânica e Biológica	Licenciatura em Bioengenharia	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/09/15 - 2023/01/31	Fundamentos da Química e da Biofísica	Mestrado Integrado em Medicina	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/10/06 - 2023/01/20	Fundamentos da Química e da Biofísica	Mestrado Integrado em Medicina (Mestrado integrado)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/02/15 - 2022/06/30	Bioquímica	Mestrado Integrado em Ciências Farmacêuticas	Universidade do Porto Faculdade de Farmácia, Portugal
2021/09/15 - 2022/02/14	Laboratório Forense II	Ciências Laboratoriais Forenses (Licenciatura)	Instituto Universitário de Ciências da Saúde, Portugal
2020/09/15 - 2021/02/14	Laboratório Forense II	Ciências Laboratoriais Forenses	Instituto Universitário de Ciências da Saúde, Portugal
2019/09/20 - 2020/02/08	Laboratorio Forense II	Ciências Laboratoriais Forenses (Licenciatura)	Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2018/09/17 - 2019/02/10	Laboratório Forense II	Ciências Laboratoriais Forenses (Licenciatura)	Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2017/09/20 - 2018/02/10	Laboratório Forense II	Ciências Laboratoriais Forenses (Licenciatura)	Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2016/10/02 - 2017/02/12	Laboratório Forense II	Ciências Laboratoriais Forenses (Licenciatura)	Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2015/10/06 - 2016/02/10	Laboratório Forense II	Ciências Laboratoriais Forenses (Licenciatura)	Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2000 - 2001	Microbiologia Geral I	Microbiologia (Licenciatura)	Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2000 - 2001	Microbiologia Geral II	Microbiologia (Licenciatura)	Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2000 - 2001	Microbiologia Geral II	Engenharia Alimentar (Licenciatura)	Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2000 - 2001	Tecnologias e Tratamento de Efluentes II	Engenharia do Ambiente (Licenciatura)	Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
1999 - 2000	Microbiologia do Ambiente	Microbiologia (Licenciatura)	Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal

Entrevista (jornal / revista)

	Descrição da atividade	Jornal / Forum
2024/11/20	Newsletter of the One Health Commission - announcement of the "One Health - Uma Saúde um contributo da Universidade" the book
2020/07/12	Researchers from Porto take advantage of the qualities of nanoparticles to combat COVID-19	Porto News
2020/07/04	nano2Prevent project: Nanoparticles to kill the virus on the protection individual equipments in the hospital and nursing home	Diário de Notícias
2020/07/01	Portuguese researchers fight viruses with nanotechnology	Portugal Textil
2020/06/30	Portuguese laboratory wants to combat Covid-19 by incorporating nanoparticles in textiles	Sapo24

Entrevista / Programa (rádio / tv)

	Programa	Tema
2024/11/26 - Atual	U.Porto Press: Livro 2 minutos "ONE HEALTH - UMA SAÚDE" com Adriano A. Bordalo e Sá

Expedição científica

	Descrição da atividade	Instituição / Organização
2023/10/17 - Atual	Short scientific mission to perform measurements using synchrotron-based infrared microspectroscopy at Alba Synchrotron. Barcelona, Spain.	Alba Synchroton, Espanha
2021/11/01 - 2021/11/06	Short scientific mission to perform measurements using synchrotron-based infrared microspectroscopy at Alba Synchrotron. Barcelona, Spain.	Centro Universitario Internacional de Barcelona, Espanha
2017/10/22 - 2017/11/26	Short scientific mission to perform measurement using synchrotron-based infrared microspectroscopy at Alba Synchrotron. Barcelona, Spain.	Centro Universitario Internacional de Barcelona, Espanha

Membro de comissão

	Descrição da atividade Tipo de participação	Instituição / Organização
2023/03/10 - Atual	Membro do Gabinete One Health Membro	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/03/06 - Atual	Membro da Comissão de Acompanhamento de Curso Programa Doutoral em Ciência Animal Membro	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020 - Atual	Editorial Board Member of the journal Marine Drugs, is the leading, peer-reviewed, open access journal on the research, development, and production of biologically and therapeutically active compounds from the sea. IF 5.1 Journal Rank: JCR - Q1 (Chemistry, Medicinal) / CiteScore - Q1 (Pharmacology, Toxicology and Pharmaceutics, miscellaneous) https://www.mdpi.com/journal/marinedrugs Outro
2019/10 - Atual	Supervisor Member of the International Doctoral Programme in Molecular and Cellular Biotechnology Applied to Health Sciences Membro	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal Universidade do Porto Faculdade de Farmácia, Portugal REQUIMTE LAQV Porto, Portugal Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019 - Atual	Editorial Board Member of the journal Chemistry, peer-reviewed, open access journal on the chemistry, indexed within Scopus, ESCI (Web of Science), CAPlus / SciFinder, and many other databases. https://www.mdpi.com/journal/chemistry Outro
2017 - Atual	Supervisor Member of the International Doctoral Programme in Sustainable Animal Nutrition and Feeding Membro	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal Universidade do Porto Faculdade de Farmácia, Portugal REQUIMTE LAQV Porto, Portugal Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2018/06 - 2022	CA16205: European Network on Understanding Gastrointestinal Absorption-related Processes (UNGAP) as management committee substitute and working group member. https://gbiomed.kuleuven.be/english/research/50000715/50000716/ungap Membro	European Cooperation in Science and Technology, Bélgica
2014 - 2018	TD1402 "Multifunctional Nanoparticles for Magnetic Hyperthermia and Indirect Radiation Therapy (RADIOMAG)" as management committee, group leader and working group member http://www.cost-radiomag.eu/ Membro	European Cooperation in Science and Technology, Bélgica
2014 - 2018	CM1307 "Targeted chemotherapy towards diseases caused by endoparasites" as Management committee substitute and working group member. Membro	European Cooperation in Science and Technology, Bélgica
2015/05/13 - 2015/05/15	Evaluation of research works presented as poster communication in the field of Chemistry at IJUP Membro	Universidade do Porto, Portugal
2012 - 2014	TD1004 "Theranostics Imaging and Therapy: An Action to Develop Novel Nanosized Systems for Imaging-Guided Drug Delivery" as working group member Membro	European Cooperation in Science and Technology, Bélgica
2013/02/13 - 2013/02/15	Evaluation of research works presented as poster communication in the field of Chemistry at IJUP Membro	Universidade do Porto, Portugal
2012/02/22 - 2012/02/24	Evaluation of research works presented as poster communication in the field of Chemistry at IJUP Membro	Universidade do Porto, Portugal
2011/11/21 - 2011/11/25	Evaluator of poster communications presented in the 11th edition of the Trends in Nanotechnology International Conference (TNT2010) Membro
2011/02/17 - 2011/02/19	Evaluation of research works presented as poster communication in the field of Chemistry at IJUP Membro	Universidade do Porto, Portugal

Outro júri / avaliação

	Descrição da atividade	Instituição / Organização
2023/11/17 - Atual	Comissão de Acompanhamento da Tese de Doutoramento em Bioquímica da Universidade Nova de Lisboa,, do estudante Bruno Miguel Soares Guerreiro.	Universidade NOVA de Lisboa, Portugal
2023/05/17 - Atual	Jury member in a public tender for applications for a scientific research position, within the project EVALUATION OF ALTERNATIVE FOOD SOURCES IN DOG FEEDING, under way at Instituto de Ciências Biomédicas de Abel Salazar da Universidade do Porto	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/02/01 - Atual	Jury member in a public tender for applications for a scientific research scholarship, within the project "NovinDog - new functional ingredients for dog food: a sustainable approach", reference poci-01-0247-feder-047003", under way at Faculdade de Farmácia da Universidade do Porto	Universidade do Porto Faculdade de Farmácia, Portugal
2023/01/12 - Atual	Jury member in a public tender for applications for a scientific research scholarship, within the project R&W Clean - Novas soluções para sensorização de parâmetros ambientais e biológicos para auxílio à desmedicalização do sector agropecuário” (POCI-01-0247-FEDER-070109), under way at Instituto de Ciências Biomédicas de Abel Salazar da Universidade do Porto	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/11/24 - Atual	Jury member in a public tender for applications for a scientific research scholarship, within the project "NovinDog - new functional ingredients for dog food: a sustainable approach", reference poci-01-0247-feder-047003", under way at Faculdade de Farmácia da Universidade do Porto	Universidade do Porto Faculdade de Farmácia, Portugal
2021/07/31 - Atual	Jury member in a public tender for a research fellowship for a graduated student in the scope of the Project HEALTH-UNORTE: Setting-up Biobanks And Regenerative Medicine Strategies to Boost Research in Neurosciences, Immunology and Infection, Musculoskeletal, Cardiovascular and Oncologic Diseases (refª NORTE-01-0145-FEDER-000039)	Universidade do Porto Faculdade de Farmácia, Portugal
2021/01/02 - Atual	Jury member in a public tender for Master's Research fellowship (Ref. REQUIMTE 2020-29), under the project PTDC/QUI-COL/30834/2017, with the financial support of FCT/MCTES through national funds and when applicable co-financed by the FEDER under the Partnership Agreement COMPETE 2020	Universidade do Porto Faculdade de Farmácia, Portugal Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2020/01 - Atual	Jury member in a public tender for Master's Research fellowship (Ref. REQUIMTE 2020-04), under the project PTDC/QUI-COL/30834/2017, with the financial support of FCT/MCTES through national funds and when applicable co-financed by the FEDER under the Partnership Agreement COMPETE 2020	Universidade do Porto Faculdade de Farmácia, Portugal
2019/11 - Atual	Jury member in a public tender for Master's Research fellowship (Ref. ICETA 2019-76), under the project PTDC/QUI-COL/30834/2017, with the financial support of FCT/MCTES through national funds and when applicable co-financed by the FEDER under the Partnership Agreement COMPETE 2020	Universidade do Porto Faculdade de Farmácia, Portugal
2019/09 - Atual	Jury member in a public tender for a Research fellowship (Reference ICETA 2019-76) at the Associated Laboratory for Green Chemistry financed by National Funds through FCT / MCTES and considering the UID's Pluriannual funding UID/QUI/50006/2019 (2020-2023).	Universidade do Porto Faculdade de Farmácia, Portugal
2019/03 - Atual	Jury member in a public tender for Master's Research fellowship (Ref. ICETA 2019-23), under the project PTDC/QUI-COL/30834/2017, with the financial support of FCT/MCTES through national funds and when applicable co-financed by the FEDER under the Partnership Agreement COMPETE 2020	Universidade do Porto Faculdade de Farmácia, Portugal
2019/03 - Atual	Jury member in a public tender for an Assistant Researcher contract (REQUIMTE 2018-46), within the framework of a project, PTDC/QUI-COL/30834/2017, financed by national funds through FCT / MCTES and the FEDER, through the COMPETE-Operational Competitiveness Factors Program (POFC) POCI-01-0145-FEDER-030834.
2018 - Atual	Jury member in a public tender for an Master's Research fellowship, within the framework of a project, PTDC/MAR-BIO/4694/2014, financed by national funds through FCT / MCTES and the FEDER, through the COMPETE-Operational Competitiveness Factors Program (POFC) POCI-01-0145-FEDER-016790.
2017/10 - Atual	Jury member in a public tender for a Research fellowship (Ref. ICETA 2017-34), under the project PTDC/MAR-BIO/4694/2014, with the financial support of FCT/MCTES through national funds and when applicable co-financed by the FEDER under the Partnership Agreement COMPETE 2020	Universidade do Porto Faculdade de Farmácia, Portugal
2024/10/02 - 2024/11/28	Member of the jury of the One Health Pet Awards promoted by the UPPartner, Lisbon. Evaluation of the categories "Health & Well-Being". https://onehealth-petawards.com/en/pet-awards-en/#panel

Tutoria

	Tópico	Nome do aluno
2023/02/01 - Atual	Nanoencapsulation of bioactive compounds for pets feed	Beatriz Silva
2021/09/01 - 2021/09/30	Entrega Transdérmica de fármacos usando biomateriais naturais no controlo da inflamação	Ana Catarina dos Santos Dias
2021/04 - 2021/08	Design of advanced resveratrol transdermal delivery systems: Evaluation of drugs permeation in skin mimetic models	Alexandra Mujica
2020/02/12 - 2020/07/31	Alginate as base polymer for hydrogels loaded with quercetin	Ludovico Esposito
2018/02/02 - 2019/11/30	Thymoquinone-loaded nanostructured lipid carrier: physicochemical characterization and interactions with a breast cancer cell line	Ong Yong Sze
2019/07/02 - 2019/09/28	Evaluation of skin permeability of bioactive compounds	Sedef Kaplan
2019/02/10 - 2019/07/02	Nanoemulsions of fractions rich in pomegranate polyphenols and their protective effect against fluoride poisoning	Kaoutar Chattahy
2018/04/02 - 2018/07/29	Pomegranate seeds applied to nanotechnology	Talal Sabraoui
2017/09/05 - 2018/06/30	Development of pH-responsive fucoidan/chitosan nanoparticles	Joana Filipa Cardoso
2016/09/02 - 2017/06/28	Controlled release of active ingredients by matrices	Abderrazzaq Essaghraoui
2015/09/03 - 2016/02/29	PLGA-Au nanospheres characterisation and validation in rheumatoid arthritis	Paola Tibalo
2010/09/15 - 2011/06/15	Development of a resistant strain of L. infantum to BNIPDaoct	Sónia Nogueira
2010/02/10 - 2010/10/20	Evaluation of the in vitro biological effects of novel bisnaphthalimidopropyl polyamine derivatives in Leishmania infantumv	Tariq Hassam
2009/09/04 - 2010/06/20	Optimisation and characterisation of nanoparticles targeted to macrophages	Joana Oliveira
2008/09/10 - 2009/06/13	Evaluation of the in vitro released compounds from polymeric nanoparticles	Joana Soares

Distinções

Prémio

2024	Best poster presentation
2021	Best oral presentation ESB 2021
2020	Best Poster presentation award
2019	Best Oral Communication in Chemistry Universidade do Porto, Portugal
2018	Best Oral Communication in Chemistry
2018	Best Poster Communication in Chemistry
2016	Best Poster, 11th Inorganic Chemistry Conference, Sintra, Portugal

Outra distinção

2024	Distinção Mérito e Relevância nos One Health Pet Awards da UPPartner
2008	Postdoctoral fellowship (BPD/37880/2007) Fundação para a Ciência e a Tecnologia, Portugal
2001	PhD fellowship (PRAXIS XXI BD/4613/2001) Fundação para a Ciência e a Tecnologia, Portugal
1998	MSc fellowship (PRAXIS XXI BM/20357/98) Fundação para a Ciência e a Tecnologia, Portugal