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Ana Sofia Almeida Costa Nunes has concluded the PhD degree in Mechanisms of Disease and Regenerative Medicine in 2019/04/02 by Universidade do Algarve - Gambelas Campus and Nova medical School from Universidade Nova de Lisboa. She has published 4 original articles and 2 review articles in specialized journals, and published 4 book chapters.
Identificação

Identificação pessoal

Nome completo
Ana Sofia Almeida Costa Nunes

Nomes de citação

  • Nunes, Sofia C.

Identificadores de autor

Ciência ID
0A1A-CA33-5100
ORCID iD
0000-0003-0802-7753

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B2) Utilizador independente (B1) Utilizador independente (B2)
Português (Idioma materno)
Formação
Grau Classificação
2015/01/01 - 2019/04/02
Concluído
 Mechanisms of Disease and Regenerative Medicine (Doutoramento)
Especialização em Oncobiology
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
"Cysteine, a facilitator of hypoxia adaptation and a promoter of drug-­-resistance-­- a new route to better diagnose and treat ovarian cancer patients" (TESE/DISSERTAÇÃO)
 Unanimously approved, Very Good, summa cum laude
2017/11/18
Concluído
 Animal Assisted Therapy: dogs and horses (Pós-Graduação)
Instituto CRIAP, Portugal
 18
2010/09 - 2012/11
Concluído
 Evolutionary and Developmental Biology (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
 18
2007/09 - 2010/09
Concluído
 Biology (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
 15
Produções

Publicações

Artigo em revista
  1. Adriana Cruz; Pedro Mota; Cristiano Ramos; Rita F. Pires; Cindy Mendes; José P. Silva; Sofia C. Nunes; Vasco D.B. Bonifácio; Jacinta Serpa. "Polyurea Dendrimer Folate-Targeted Nanodelivery of l-Buthionine sulfoximine as a Tool to Tackle Ovarian Cancer Chemoresistance". Antioxidants 9 2 (2020): 133. http://dx.doi.org/10.3390/antiox9020133.
    10.3390/antiox9020133
  2. Inês Santos; Cristiano Ramos; Cindy Mendes; Catarina O. Sequeira; Catarina S. Tomé; Dalila G.H. Fernandes; Pedro Mota; et al. "Targeting Glutathione and Cystathionine ß-Synthase in Ovarian Cancer Treatment by Selenium–Chrysin Polyurea Dendrimer Nanoformulation". Nutrients (2019): http://dx.doi.org/10.3390/nu11102523.
    10.3390/nu11102523
  3. Nunes, Sofia C. (0A1A-CA33-5100); Serpa, Jacinta. "Glutathione in Ovarian Cancer: A Double-Edged Sword". International Journal of Molecular Sciences (2018): http://dx.doi.org/10.3390/ijms19071882.
    10.3390/ijms19071882
  4. Nunes, Sofia C.; Ramos, Cristiano; Lopes-Coelho, Filipa; Sequeira, Catarina O.; Silva, Fernanda; Gouveia-Fernandes, Sofia; Rodrigues, Armanda; et al. "Cysteine allows ovarian cancer cells to adapt to hypoxia and to escape from carboplatin cytotoxicity". Scientific Reports 8 1 (2018): http://dx.doi.org/10.1038/s41598-018-27753-y.
    10.1038/s41598-018-27753-y
  5. Nunes, SC; Lopes-Coelho, F; Gouveia-Fernandes, S; Ramos, C; Pereira, Sofia A; Serpa, J. "Cysteine boosters the evolutionary adaptation to CoCl2 mimicked hypoxia conditions, favouring carboplatin resistance in ovarian cancer". BMC Evolutionary Biology (2018): http://dx.doi.org/10.1186/s12862-018-1214-1.
    10.1186/s12862-018-1214-1
  6. Lopes-Coelho, F; Gouveia-Fernandes, S; Nunes, SC; Serpa, J. "Metabolic Dynamics in Breast Cancer: Cooperation between Cancer and Stromal Cells". J Clin Breast Cancer Res 1 (2017): 1001. https://pdfs.semanticscholar.org/f36c/b516eea94a3b1864b92f5bb88766087234a8.pdf.
    Publicado
Capítulo de livro
  1. Nunes, Sofia C. (0A1A-CA33-5100). "Exploiting cancer cells metabolic adaptability to enhance therapy response in cancer". In Tumor microenvironment - the main driver of metabolic adaptation. Springer-Nature, 2020.
    Publicado
  2. Nunes, Sofia C (0A1A-CA33-5100); Serpa, Jacinta. "Recycling the interspecific relations with epithelial cells: bacteria and cancer metabolic symbiosis". In Tumor microenvironment - the main driver of metabolic adaptation. Springer-Nature, 2020.
    Publicado
  3. Nunes, Sofia C. (0A1A-CA33-5100). "Tumor microenvironment - selective pressures boosting cancer progression". In Tumor microenvironment - the main driver of metabolic adaptation. Springer-Nature, 2020.
    Publicado
  4. Carreira-Barbosa, Filipa; Nunes, Sofia C. (0A1A-CA33-5100). "Wnt signaling: paths for cancer progression". In Tumor microenvironment - the main driver of metabolic adaptation. Springer-Nature, 2020.
    Publicado
Poster em conferência
  1. Ana Felix; Fernanda Silva; Cristiano Ramos; Filipa Lopes-Coelho; Sofia C. Nunes; Jacinta Serpa. "LAMININ332 (a3; ß3;¿2) genes and protein expression in cervical carcinomas". Trabalho apresentado em 25th Biennial Congress of the European Association for Cancer Research, 2018.
  2. Nunes, Sofia C. (0A1A-CA33-5100); Filipa Coelho; João B. Vicente; Ana Felix; Sofia A. Pereira; Jacinta Serpa. "Cysteine metabolism protects ovarian clear cell carcinoma (OCCC) cells in hypoxia". Trabalho apresentado em Cancer and Metabolism Conference, Cambridge, UK (Abcam), 2015.
  3. Nunes, S. (0A1A-CA33-5100); Dey, S.; Chelo, I.; Ferreira, A.; Teotónio, H.. "Population extinction and the role of standing diversity in experimental Caenorhabiditis elegans". Trabalho apresentado em X Encontro Nacional de Biologia Evolutiva, 2014.
  4. Dey, S.; Ibanez, P.; Nunes, A. S.; Proulx, S.; Teotónio, H.. "Adaptation to fluctuating anoxic environments in Caenorhabditis elegans. Evolutionary Biology of Caenorhabditis and other Nematodes". Trabalho apresentado em Evolutionary Biology of Caenorhabditis and other Nematodes, 2014.
Resumo em conferência
  1. Felix, A; Silva, F; Ramos, C; Lopes-Coelho, F; Nunes, S; Serpa, J. "PO-468 Laminin332 (a3; ß3;¿2) genes and protein expression in cervical carcinomas". 2018.
    10.1136/esmoopen-2018-eacr25.975
  2. Nunes, Sofia C. (0A1A-CA33-5100); Cristiano Ramos; João B. Vicente; Sofia A. Pereira; Jacinta Serpa. "Enzymes involved in cysteine metabolism underlie hypoxia adaptation in ovarian cancer". Trabalho apresentado em 8th International Conference on Tumor Microenvironment: progression, therapy & Prevention, Lisbon, 2018.
Atividades

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2019/07/19 - Atual Medical Writing

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2019/11/25 - Atual Co-Editor of the Special Issue "New Therapies based on Cancer Metabolic Remodelling" in Molecules