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António Ribeiro is Professor at University of Coimbra and he is a researcher affiliated to Instituto de Investigação e Inovação em Saúde (I3S). Trained in Pharmacy, he teaches Pharmaceutical Technology and nanotechnology at the School of Pharmacy, University of Coimbra. He has acquired a solid foundation in the domain of micro and nanoencapsulation at the University Paris V (Prof. JC Chaumeil) and McGill University (Prof. RJ Neufeld). His research has been focused on the micro and nanoencapsulation of biologically active materials including cells, enzymes, nucleotides, genomic DNA, and therapeutic peptides and proteins. His accumulated experience on drugs’ formulation allowed him in 2014 to develop pharmaceutical implants for extended release of drugs in a collaboration with pharmaceutical industry. He has supervised more than 30 postgraduate students some of them either as visiting schoolar at University of Paris V in 2016 or Invited Researcher by Universities of Pernambuco and Piaui in Brazil between 2013-2015. António Ribeiro has worked for more than 20 years on development of drug delivery systems, including micro-and nanocarriers, biodegradable polymeric, and research leading to the publication of more than 100 articles 10 book chapters. His awards include several Most cited and downloaded papers from Elsevier. His research has been funded by the Portuguese Government Research Foundation (FCT), Fundação Calouste Gulbenkian, FLAD and other agencies. He is the author of highly-cited experimental papers in the domain of micro- and nanocapsulation and his main focus at this time is on design of nanodelivery systems for nucleic acids towards therapeutic strategies for neurodegenerative diseases.
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Identificação

Identificação pessoal

Nome completo
António José Ribeiro

Nomes de citação

  • Ribeiro, J António
  • Ribeiro A
  • Ribeiro AJ

Identificadores de autor

Ciência ID
0C17-C80B-ECD6
ORCID iD
0000-0002-1399-8944

Endereços de correio eletrónico

  • aribeiro@ff.uc.pt (Profissional)

Moradas

  • Faculdade de Farmácia, Azinhaga de Santa Comba, 3000-548, Coimbra, Coimbra, Portugal (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia
  • Ciências da Engenharia e Tecnologias - Nanotecnologia - Nanomateriais
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Diagnóstico e Terapias de Base Genética

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Francês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador elementar (A2) Utilizador independente (B1) Utilizador elementar (A1) Utilizador independente (B2) Utilizador elementar (A1)
Formação
Grau Classificação
2012
Concluído
 Ciências Farmacêuticas (Título de Agregado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
"A nanoencapsulação como estratégia para aumentar a absorção intestinal da insulina" (TESE/DISSERTAÇÃO)
 Aprovado por maioria
1997
Concluído
 Biopharmacie e Pharmacotechnie (Doutoramento)
Université Paris Descartes, França
"Valorisation des extraits d'ail. Mise au point galénique de sphéroïdes destinés à la voie orale." (TESE/DISSERTAÇÃO)
 Très Honorable
1992
Concluído
 DEA en Pharmacotechnie et Biopharmacie (DEA)
Especialização em Mas
Université Paris-Sud, França
"Valorisation de l´huile essentielle de romarin à travers la microencapsulation " (TESE/DISSERTAÇÃO)
 14/20
1991
Concluído
 Ciências Farmacêuticas (Licenciatura)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"N/A" (TESE/DISSERTAÇÃO)
 Quinze valores
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2015 - Atual Investigador (Investigação) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2009 - 2014/12/31 Investigador principal (carreira) (Investigação) Universidade de Coimbra Faculdade de Farmácia, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2006/01/21 - 2022/01/22 Professor Auxiliar (Docente Universitário) Universidade de Coimbra, Portugal
1998/02/08 - 2005/11/30 Professor Auxiliar (Docente Universitário) Instituto Superior de Ciências da Saúde-Norte (ISCS-N/CESPU), Portugal
1998/01/01 - 2000/12/31 Professor Auxiliar Convidado (Docente Universitário) Universidade do Porto Faculdade de Farmácia, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/01/22 - Atual Associate Professor Universidade de Coimbra Faculdade de Farmácia, Portugal
Projetos

Bolsa

Designação Financiadores
2016/07/01 - 2019/06/30 Desenvolvimento e caracterização de complexos micelares inteligentes para a terapêutica do cancro do pulmão
P2020-PTDC/CTM-BIO/1518/2014
Investigador
Universidade de Coimbra Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2017/01/01 - 2018/12/31 Adsorção de um fragmento de anticorpo a nanopartículas poliméricas para aumentar a absorção intestinal da insulina
FCT/CAPES - N.º 8503/14-1
Investigador responsável
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2013/01/01 - 2013/12/31 Preparation and characterization of polymeric micelles as carriers for poor soluble drugs
EXPL/CTM-NAN/1151/2012
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2005/09/01 - 2007/08/31 Improvement of peptidic drug oral availability through encapsulation in polyelctrolyte complex nanoparticles
POCI/SAU-FCF/59940/2004
Investigador responsável
Instituto Superior de Ciências da Saúde-Norte (ISCS-N/CESPU), Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2005 - 2007 Microencapsulation of probiotic bacteria to enhance survival during upper gastrointestinal tract passage
1F/10/2005/CESPU
Investigador
Instituto Superior de Ciências da Saúde-Norte (ISCS-N/CESPU), Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Concluído
2006 - 2006 Ensaio in vitro para quantificação da actividade da insulina encapsulada em nanopartículas de polissacáridos
2F/11/2006/CESPU
Investigador
Instituto Superior de Ciências da Saúde-Norte (ISCS-N/CESPU), Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Concluído

Projeto

Designação Financiadores
2017/01/01 - 2019/12/31 Pharmaceutical development of polymeric implants for sustained release of drugs-IMPUCT 2
IMPUCT 17650
Investigador responsável
Universidade de Coimbra, Portugal
Em curso
2016 - 2019 Neurosciences and Neurologic Disease Research Initiative at i3S
NORTE-01-0145-FEDER-000008
Investigador
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Concluído
2013/06/01 - 2015/05/31 Pharmaceutical development of polymeric implants for sustained release of drugs-IMPUCT
33849-IMPUCT
Investigador responsável
Universidade de Coimbra, Portugal
 Agência Nacional de Inovação SA
Concluído
2014/01/01 - 2014 Strategic Project - UI 177 - 2014
PEst-OE/SAU/UI0177/2014
Centre for Pharmaceutical Studies, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em revista
  1. A.S. Sousa; J. Serra; C. Estevens; R. Costa; A.J. Ribeiro. "Leveraging a multivariate approach towards enhanced development of direct compression extended release tablets". International Journal of Pharmaceutics (2023): https://doi.org/10.1016/j.ijpharm.2023.123432.
    10.1016/j.ijpharm.2023.123432
  2. B. Rama; A. J. Ribeiro. "Role of nanotechnology in the prolonged release of drugs by the subcutaneous route". Expert Opinion on Drug Delivery (2023): https://doi.org/10.1080/17425247.2023.2214362.
    10.1080/17425247.2023.2214362
  3. Bruno Pessoa; Mar Collado-Gonzalez; Giuseppina Sandri; António Ribeiro. "Chitosan/Albumin Coating Factorial Optimization of Alginate/Dextran Sulfate Cores for Oral Delivery of Insulin". Marine Drugs (2023): https://doi.org/10.3390/md21030179.
    10.3390/md21030179
  4. A. S. Sousa; J. Serra; C. Estevens; R. Costa; A. J. Ribeiro. "A quality by design approach in oral extended release drug delivery systems: where we are and where we are going?". Journal of Pharmaceutical Investigation (2023): https://doi.org/10.1007/s40005-022-00603-w.
    10.1007/s40005-022-00603-w
  5. Bruno Costa; Beatriz Boueri; Claudia Oliveira; Isabel Silveira; Antonio J. Ribeiro. "Lipoplexes and polyplexes as nucleic acids delivery nanosystems: The current state and future considerations". Expert Opinion on Drug Delivery (2022): https://doi.org/10.1080/17425247.2022.2075846.
    10.1080/17425247.2022.2075846
  6. Moreno de Paiva, Juliana; Gomes de Oliveira Barud, Hélida; Franco, Douglas Faza; Meneguin, Andréia Bagliotti; Ribeiro, António José; Barud, Hernane S.; Nalin, Marcelo. "THE IMPACT OF P/Ca MOLAR RATIO ON PHYSICOCHEMICAL AND RELEASE PROPERTIES OF CALCIUM POLYPHOSPHATE COACERVATES". Materials Chemistry and Physics (2021): 124471. http://dx.doi.org/10.1016/j.matchemphys.2021.124471.
    10.1016/j.matchemphys.2021.124471
  7. "Sterculia striata gum as a potential oral delivery system for protein drugs". International Journal of Biological Macromolecules 164 (2020): 1683-1692. http://dx.doi.org/10.1016/j.ijbiomac.2020.07.276.
    10.1016/j.ijbiomac.2020.07.276
  8. Ana Cláudia Santos; Miguel Pereira-Silva; Catarina Guerra; Diana Costa; Diana Peixoto; Irina Pereira; Inês Pita; António J. Ribeiro; Francisco Veiga. "Topical Minoxidil-Loaded Nanotechnology Strategies for Alopecia". Cosmetics 7 2 (2020): 21-21. https://doi.org/10.3390/cosmetics7020021.
    10.3390/cosmetics7020021
  9. Collado-González, Mar; Ferreri, Maria Cristina; Freitas, Alessandra R.; Santos, Ana Cláudia; Ferreira, Nuno R.; Carissimi, Guzmán; Sequeira, Joana A. D.; et al. "Complex Polysaccharide-Based Nanocomposites for Oral Insulin Delivery". Marine Drugs 18 1 (2020): 55. http://dx.doi.org/10.3390/md18010055.
    10.3390/md18010055
  10. Karolina Carneiro Morais Macedo; Luíse Lopes Chaves; Alexandre Couto Carneiro Vieira; Daniela Nadvorny; Regina Célia Monteiro de Paula; Durcilene Alves Silva; Francisco Veiga; António José Ribeiro; Edson Cavalcanti Silva-Filho. "Study of the effect of solvent on acetylate cashew gum-based nanoparticles properties and antimicrobial activity". Matéria (Rio de Janeiro) 25 4 (2020): https://doi.org/10.1590/s1517-707620200004.1148.
    10.1590/s1517-707620200004.1148
  11. Santos, Ana Cláudia; Sequeira, Joana A.D.; Pereira, Irina; Cabral, Célia; Collado Gonzallez, Mar; Fontes-Ribeiro, C.; Ribeiro, António J.; Lvov, Yuri M.; Veiga, Francisco J.. "Sonication-assisted Layer-by-Layer self-assembly nanoparticles for resveratrol delivery". Materials Science and Engineering: C 105 (2019): 110022. http://dx.doi.org/10.1016/j.msec.2019.110022.
    10.1016/j.msec.2019.110022
  12. Ana Cláudia Santos; Irina Pereira; Miguel Pereira-Silva; Laura Ferreira; Mariana Caldas; Mar Collado-González; Mariana Magalhães; et al. "Nanotechnology-based formulations for resveratrol delivery: Effects on resveratrol in vivo bioavailability and bioactivity". Colloids and Surfaces B: Biointerfaces 180 (2019): 127-140. https://doi.org/10.1016/j.colsurfb.2019.04.030.
    10.1016/j.colsurfb.2019.04.030
  13. Pinho, A.R.; Fortuna, A.; Falcão, A.; Santos, A.C.; Seiça, R.; Estevens, C.; Veiga, F.; Ribeiro, A.J.. "Comparison of ELISA and HPLC-MS methods for the determination of exenatide in biological and biotechnology-based formulation matrices". Journal of Pharmaceutical Analysis 9 3 (2019): 143-155. http://dx.doi.org/10.1016/j.jpha.2019.02.001.
    10.1016/j.jpha.2019.02.001
  14. Santos, Ana Cláudia; Pereira, Irina; Magalhães, Mariana; Pereira-Silva, Miguel; Caldas, Mariana; Ferreira, Laura; Figueiras, Ana; Ribeiro, António J.; Veiga, Francisco. "Targeting Cancer Via Resveratrol-Loaded Nanoparticles Administration: Focusing on In Vivo Evidence". The AAPS Journal 21 4 (2019): http://dx.doi.org/10.1208/s12248-019-0325-y.
    10.1208/s12248-019-0325-y
  15. Ana Cláudia Santos; Francisca Morais; Ana Simões; Irina Pereira; Joana A. D. Sequeira; Miguel Pereira-Silva; Francisco Veiga; António Ribeiro. "Nanotechnology for the development of new cosmetic formulations". Expert Opinion on Drug Delivery (2019): 1-18. https://doi.org/10.1080/17425247.2019.1585426.
    10.1080/17425247.2019.1585426
  16. Eliadna de Lemos Vasconcelos Silva; Antônia Carla de Jesus Oliveira; Yuri Basílio Gomes Patriota; António José Ribeiro; Francisco Veiga; Fernando Hallwass; Edson Cavalcanti Silva-Filho; et al. "Solvent-free synthesis of acetylated cashew gum for oral delivery system of insulin". Carbohydrate Polymers 207 (2019): 601-608. https://doi.org/10.1016/j.carbpol.2018.11.071.
    10.1016/j.carbpol.2018.11.071
  17. Joana A. D. Sequeira; Ana C. Santos; João Serra; Catarina Estevens; Raquel Seiça; Francisco Veiga; António J. Ribeiro. "Subcutaneous delivery of biotherapeutics: challenges at the injection site". Expert Opinion on Drug Delivery 16 2 (2019): 143-151. https://doi.org/10.1080/17425247.2019.1568408.
    10.1080/17425247.2019.1568408
  18. Ana Cláudia Santos; Francisco J. Veiga; Joana A. D. Sequeira; Ana Fortuna; Amílcar Falcão; Irina Pereira; Pravin Pattekari; Carlos Fontes-Ribeiro; António J. Ribeiro. "First-time oral administration of resveratrol-loaded layer-by-layer nanoparticles to rats – a pharmacokinetics study". The Analyst (2019): https://doi.org/10.1039/C8AN01998C.
    10.1039/C8AN01998C
  19. Silva, Eliadna de Lemos Vasconcelos; Oliveira, Antônia Carla de Jesus; Silva-Filho, Edson Cavalcanti; Ribeiro, António José; Veiga, Francisco; Soares, Monica Felts de La Roca; Wanderley, Almir Gonçalves; et al. "Nanostructured polymeric system based of cashew gum for oral admnistration of insulin". Matéria (Rio de Janeiro) 24 3 (2019): http://dx.doi.org/10.1590/s1517-707620190003.0712.
    10.1590/s1517-707620190003.0712
  20. Margarida Viola; Joana Sequeira; Raquel Seiça; Francisco Veiga; João Serra; Ana C. Santos; António J. Ribeiro. "Subcutaneous delivery of monoclonal antibodies: How do we get there?". Journal of Controlled Release 286 (2018): 301-314. https://doi.org/10.1016/j.jconrel.2018.08.001.
    10.1016/j.jconrel.2018.08.001
  21. Daniela Nadvorny; José Lamartine Soares-Sobrinho; Monica F. de La Roca Soares; Antônio José Ribeiro; Francisco Veiga; Gustavo M. Seabra. "Molecular dynamics simulations reveal the influence of dextran sulfate in nanoparticle formation with calcium alginate to encapsulate insulin". Journal of Biomolecular Structure and Dynamics (2018): 1-6. https://doi.org/10.1080/07391102.2017.1318305.
    10.1080/07391102.2017.1318305
  22. FEDALTO, Mayra Bruna; SANTOS, Ana Cláudia; SANSÃO, Bruna Dos Santos; ZANIN, Sandra Maria Warumby; Miguel, Marilis Dallarmi; RIBEIRO, António José. "OBTENÇÃO DE NANOPARTÍCULAS BIODEGRADÁVEIS DE IBUPROFENO ENCAPSULADAS POR “LAYER-BY-LAYER (LBL) SELF-ASSEMBLY” - CAMADA POR CAMADA AUTO-ESTRUTURADAS". Visão Acadêmica 18 4 (2018): http://dx.doi.org/10.5380/acd.v18i4.57801.
    10.5380/acd.v18i4.57801
  23. Santos, A.C.; Ferreira, C.; Veiga, F.; Ribeiro, A.J.; Panchal, A.; Lvov, Y.; Agarwal, A.. "Halloysite clay nanotubes for life sciences applications: From drug encapsulation to bioscaffold". Advances in Colloid and Interface Science 257 (2018): 58-70. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048483515&partnerID=MN8TOARS.
    10.1016/j.cis.2018.05.007
  24. Marlene Lopes; Barbara Abrahim; Francisco Veiga; Raquel Seiça; Lucio Mendes Cabral; Philippe Arnaud; José Carlos Andrade; Antonio J. Ribeiro. "Preparation methods and applications behind alginate-based particles". Expert Opinion on Drug Delivery 14 6 (2017): 769-782. https://doi.org/10.1080%2F17425247.2016.1214564.
    10.1080/17425247.2016.1214564
  25. Cordeiro, M.S.F.; da Silva, C.M.B.; de M. Vieira, A.C.Q.; Nadvorny, D.; de Sá, L.L.F.; de Souza, F.R.L.; Nunes, L.C.C.; et al. "Biopolymers and pilocarpine interaction study for use in drug delivery systems (DDS)". Journal of Thermal Analysis and Calorimetry 127 2 (2017): 1777-1785. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988602734&partnerID=MN8TOARS.
    10.1007/s10973-016-5796-9
  26. Lopes, M.; Aniceto, D.; Abrantes, M.; Simões, S.; Branco, F.; Vitória, I.; Botelho, M.F.; et al. "In vivo biodistribution of antihyperglycemic biopolymer-based nanoparticles for the treatment of type 1 and type 2 diabetes". European Journal of Pharmaceutics and Biopharmaceutics 113 (2017): 88-96. http://www.scopus.com/inward/record.url?eid=2-s2.0-85008420130&partnerID=MN8TOARS.
    10.1016/j.ejpb.2016.11.037
  27. Oliveira, C.L.; Veiga, F.; Varela, C.; Roleira, F.; Tavares, E.; Silveira, I.; Ribeiro, A.J.. "Characterization of polymeric nanoparticles for intravenous delivery: Focus on stability". Colloids and Surfaces B: Biointerfaces 150 (2017): 326-333. http://www.scopus.com/inward/record.url?eid=2-s2.0-85006136637&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2016.10.046
  28. Bengaied, Dorsaf; Ribeiro, Antonio; Amri, Mohamed; Scherman, Daniel; Arnaud, Philippe. "Reduction of Hepatotoxicity Induced by Doxorubicin". Journal of Integrative Oncology 06 03 (2017): http://dx.doi.org/10.4172/2329-6771.1000193.
    10.4172/2329-6771.1000193
  29. António J. Ribeiro; Flávia R. Lucena de Souza; Janira M.N.A. Bezerra; Claudia Oliveira; Daniela Nadvorny; Monica F. de La Roca Soares; Lívio C.C. Nunes; et al. "Gums’ based delivery systems: Review on cashew gum and its derivatives". Carbohydrate Polymers 147 (2016): 188-200. http://dx.doi.org/10.1016/j.carbpol.2016.02.042.
    10.1016/j.carbpol.2016.02.042
  30. Ribeiro, António. "Dual chitosan/albumin-coated alginate/dextran sulfate nanoparticles for enhanced oral delivery of insulin". Journal of Controlled Release (2016):
    10.1016/j.jconrel.2016.04.012
  31. Ribeiro, António. "Recent Advances in Nucleic Acid-Based Delivery: From Bench to Clinical Trials in Genetic Diseases". Journal of Biomedical Nanotechnology (2016):
    10.1166/jbn.2016.2245
  32. Moreira, D.L.; Ribeiro, S.; Ribeiro, A.J.; Veiga, F.B.; Sobrinho, J.L.S.; Filho, E.C.S.; de Sá, L.L.F.; de Freitas, R.M.; Nunes, L.C.C.. "Development and validation of a new method to quantify pilocarpine in tablets by HPLC-DAD". Current Pharmaceutical Analysis 12 4 (2016): 315-324. http://www.scopus.com/inward/record.url?eid=2-s2.0-84989223280&partnerID=MN8TOARS.
    10.2174/1573412912666151111222510
  33. Lopes, M.; Derenne, A.; Pereira, C.; Veiga, F.; Seiça, R.; Sarmento, B.; Ribeiro, A.; Ribeiro, António. "Impact of the in vitro gastrointestinal passage of biopolymer-based nanoparticles on insulin absorption". RSC Advances 6 24 (2016): 20155-20165. http://www.scopus.com/inward/record.url?eid=2-s2.0-84958957806&partnerID=MN8TOARS.
    10.1039/c5ra26224k
  34. Ribeiro, António. "Probing insulin bioactivity in oral nanoparticles produced by ultrasonication-assisted emulsification/internal gelation". International Journal of Nanomedicine (2015):
    10.2147/IJN.S86313
  35. Liu, Dongfei; Zhang, Hongbo; Makila, Ermei; Fan, Jin; Herranz-Blanco, Barbara; Wang, Chang-Fang; Rosa, Ricardo; et al. "Microfluidic assisted one-step fabrication of porous silicon@acetalated dextran nanocomposites for precisely controlled combination chemotherapy". Biomaterials 39 (2015): 249-259. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000347760600026&KeyUID=WOS:000347760600026.
    10.1016/j.biomaterials.2014.10.079
  36. Oliveira, C.; Silveira, I.; Veiga, F.; Ribeiro, A.J.. "Recent advances in characterization of nonviral vectors for delivery of nucleic acids: Impact on their biological performance". Expert Opinion on Drug Delivery 12 1 (2015): 27-39. http://www.scopus.com/inward/record.url?eid=2-s2.0-84919451836&partnerID=MN8TOARS.
    10.1517/17425247.2014.945421
  37. Lopes, M.; Simões, S.; Veiga, F.; Seiça, R.; Ribeiro, A.. "Why most oral insulin formulations do not reach clinical trials". Therapeutic Delivery 6 8 (2015): 973-987. http://www.scopus.com/inward/record.url?eid=2-s2.0-84945585107&partnerID=MN8TOARS.
    10.4155/TDE.15.47
  38. Santos, A.C.; Pattekari, P.; Jesus, S.; Veiga, F.; Lvov, Y.; Ribeiro, A.J.. "Sonication-Assisted Layer-by-Layer Assembly for Low Solubility Drug Nanoformulation". ACS Applied Materials and Interfaces 7 22 (2015): 11972-11983. http://www.scopus.com/inward/record.url?eid=2-s2.0-84935833558&partnerID=MN8TOARS.
    10.1021/acsami.5b02002
  39. Lira, Luiz Marcelo; da Silva, Luiz Cláudio Rodrigues Pereira; Ribeiro, Antônio J; Veiga, Francisco; Rodrigues, Carlos Rangel; do Carmo, Flávia Almada; de Sousa, Valéria Pereira; et al. "Crystalline forms of nonprotein drugs filed in Brazil from 1995–2005". Pharmaceutical Patent Analyst 3 2 (2014): 151-161. http://dx.doi.org/10.4155/ppa.14.5.
    10.4155/ppa.14.5
  40. Silva, A.. "Segregated Delivery of Rifampicin and Isoniazid from Fixed Dose Combination Bilayer Tablets for the Treatment of Tuberculosis". British Journal of Pharmaceutical Research 4 14 (2014): 1781-1801. http://dx.doi.org/10.9734/bjpr/2014/11525.
    10.9734/bjpr/2014/11525
  41. Lopes, M.A.; Abrahim, B.A.; Cabral, L.M.; Rodrigues, C.R.; Seiça, R.M.F.; de Baptista Veiga, F.J.; Ribeiro, A.J.. "Intestinal absorption of insulin nanoparticles: Contribution of M cells". Nanomedicine: Nanotechnology, Biology, and Medicine 10 6 (2014): 1139-1151. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905217981&partnerID=MN8TOARS.
    10.1016/j.nano.2014.02.014
  42. Lopes, M.A.; Abrahim, B.A.; Seiça, R.; Veiga, F.; Rodrigues, C.R.; Ribeiro, A.J.. "Intestinal uptake of insulin nanoparticles: Facts or myths?". Current Pharmaceutical Biotechnology 15 7 (2014): 629-638. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925850213&partnerID=MN8TOARS.
    10.2174/1389201015666140915151319
  43. Santos, A.C.; Costa, G.; Veiga, F.; Figueiredo, I.V.; Batista, M.T.; Ribeiro, A.J.. "Advance in methods studying the pharmacokinetics of polyphenols". Current Drug Metabolism 15 1 (2014): 96-115. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896321026&partnerID=MN8TOARS.
    10.2174/1389200214666131211155028
  44. Ribeiro, A.J.. "Nanotechnology as a strategy to improve treatment of diabetes". Current Pharmaceutical Biotechnology 15 7 (2014): 589-589. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925881620&partnerID=MN8TOARS.
  45. Lopes, M.; Abrahim, B. A.; Rodrigues, C. R.; Veiga, L. M. Cabralf.; Ribeiro, A. J.. "Alginate-Based Micro and Nanoparticles Coated with Chitosan". Journal of Chitin and Chitosan Science 1 3 (2013): 173-176. http://dx.doi.org/10.1166/jcc.2013.1025.
    10.1166/jcc.2013.1025
  46. Machado, Alexandra H. E.; Lundberg, Dan; Ribeiro, António; Veiga, Francisco J. B.; Miguel, Maria Graça; Lindman, Bjorn; Olsson, Ulf. "Encapsulation of DNA in Macroscopic and Nanosized Calcium Alginate Gel Particles". Langmuir (2013):
    10.1021/la4032927
  47. Pupe, Carolina Gonçalves; Do Carmo, Flávia Almada; De Sousa, Valéria Pereira; Lopes, Marlene; Abrahim-Vieira, Bárbara; Ribeiro, António José; Veiga, Francisco; et al. "Development of a Doxazosin and Finasteride Transdermal System for Combination Therapy of Benign Prostatic Hyperplasia". Journal of Pharmaceutical Sciences (2013): n/a-n/a.
    10.1002/jps.23715
  48. Santos, Ana C; Cunha, Joana; Veiga, F; Cordeiro-da-Silva, A; Ribeiro, Antonio J. "Ultrasonication of insulin-loaded microgel particles produced by internal gelation: Impact on particle's size and insulin bioactivity.". Carbohydrate polymers 98 2 (2013): 1397-408.
    10.1016/j.carbpol.2013.06.063
  49. Machado, Alexandra H. E.; Lundberg, Dan; Ribeiro, Antonio J.; Veiga, Francisco J.; Lindman, Bjorn; Miguel, Maria G.; Olsson, Ulf. "Preparation of Calcium Alginate Nanoparticles Using Water-in-Oil (W/O) Nanoemulsions". Langmuir 28 9 (2012): 4131-4141.
    10.1021/la204944j
  50. Santos, Ana Claudia; Veiga, Francisco; Ribeiro, Antonio J.. "New delivery systems to improve the bioavailability of resveratrol". Expert Opinion on Drug Delivery 8 8 (2011): 973-990.
    10.1517/17425247.2011.581655
  51. Machado, Alexandra H. E.; Lundberg, Dan; Ribeiro, Antonio J.; Veiga, Francisco J.; Miguel, Maria G.; Lindman, Bjorn; Olsson, Ulf. "Interactions between DNA and Nonionic Ethylene Oxide Surfactants are Predominantly Repulsive". Langmuir 26 16 (2010): 13102-13109.
    10.1021/la101403j
  52. Reis, C.; Ribeiro, A.; Veiga, F.; Neufeld, R.; Damgé, C.. "O40 Administration orale d’insuline : vers une nouvelle approche". Diabetes & Metabolism 35 (2009): A11. http://dx.doi.org/10.1016/s1262-3636(09)71732-x.
    10.1016/s1262-3636(09)71732-x
  53. Moran, M. C.; Laranjeira, T.; Ribeiro, A.; Miguel, M. G.; Lindman, B.. "Chitosan-DNA Particles for DNA Delivery: Effect of Chitosan Molecular Weight on Formation and Release Characteristics". Journal of Dispersion Science and Technology 30 10 (2009): 1494-1499.
    10.1080/01932690903123403
  54. Woitiski, Camile Baldin; Veiga, Francisco; Ribeiro, Antonio; Neufeld, Ronald. "Design for optimization of nanoparticles integrating biomaterials for orally dosed insulin". European Journal of Pharmaceutics and Biopharmaceutics 73 1 (2009): 25-33.
    10.1016/j.ejpb.2009.06.002
  55. Woitiski, Camile B.; Neufeld, Ronald J.; Ribeiro, Antonio J.; Veiga, Francisco. "Colloidal carrier integrating biomaterials for oral insulin delivery: Influence of component formulation on physicochemical and biological parameters". Acta Biomaterialia 5 7 (2009): 2475-2484.
    10.1016/j.actbio.2009.03.007
  56. Reis, Catarina P.; Veiga, Francisco J.; Ribeiro, Antonio J.; Neufeld, Ronald J.; Damge, Christiane. "Nanoparticulate Biopolymers Deliver Insulin Orally Eliciting Pharmacological Response". Journal of Pharmaceutical Sciences 97 12 (2008): 5290-5305.
    10.1002/jps.21347
  57. Reis, Catarina Pinto; Ribeiro, Antonio J.; Veiga, Francisco; Neufeld, Ronald J.; Damge, Christiane. "Polyelectrolyte biomaterial interactions provide nanoparticulate carrier for oral insulin delivery". Drug Delivery 15 2 (2008): 127-139.
    10.1080/10717540801905165
  58. Reis, Catarina P.; Figueiredo, Isabel V.; Carvalho, Rui A.; Jones, John; Nunes, Patricia; Soares, Ana F.; Silva, Cristina F.; et al. "Toxicological assessment of orally delivered nanoparticulate insulin". Nanotoxicology 2 4 (2008): 205-217.
    10.1080/17435390802398309
  59. Woitiski, C.B.; Carvalho, R.A.; Ribeiro, A.J.; Neufeld, R.J.; Veiga, F.. "Strategies toward the improved oral delivery of insulin nanoparticles via gastrointestinal uptake and translocation". BioDrugs 22 4 (2008): 223-237. http://www.scopus.com/inward/record.url?eid=2-s2.0-47049095564&partnerID=MN8TOARS.
    10.2165/00063030-200822040-00002
  60. Reis, Catarina Pinto; Veiga, Francisco; Nunes, Patricia; Soares, Ana Francisca; Laranjeira, Tania; Carvalho, Rui; Jones, John; et al. "Toxicological in vivo studies of an oral insulin nanosystern". Toxicology Letters 172 (2007): S90-S90. http://dx.doi.org/10.1016/j.toxlet.2007.05.250.
    10.1016/j.toxlet.2007.05.250
  61. Sarmento, Bruno; Ribeiro, Antonio; Veiga, Francisco; Ferreira, Domingos; Neufeld, Ronald. "Oral bioavailability of insulin contained in polysaccharide nanoparticles". Biomacromolecules 8 10 (2007): 3054-3060.
    10.1021/bm0703923
  62. Reis, Catarina Pinto; Ribeiro, Antonio J.; Neufeld, Ronald J.; Veiga, Francisco. "Alginate microparticles as novel carrier for oral insulin delivery". Biotechnology and Bioengineering 96 5 (2007): 977-989.
    10.1002/bit.21164
  63. Sarmento, B.; Ribeiro, A.; Veiga, F.; Sampaio, P.; Neufeld, R.; Ferreira, D.. "Alginate/Chitosan nanoparticles are effective for oral insulin delivery". Pharmaceutical Research 24 12 (2007): 2198-2206.
    10.1007/s11095-007-9367-4
  64. Reis, Catarina Pinto; Ribeiro, Antonio J.; Houng, Simone; Veiga, Francisco; Neufeld, Ronald J.. "Nanoparticulate delivery system for insulin: Design, characterization and in vitro/in vivo bioactivity". European Journal of Pharmaceutical Sciences 30 5 (2007): 392-397.
    10.1016/j.ejps.2006.12.007
  65. Sarmento, B.; Ribeiro, A. J.; Veiga, F.; Ferreira, D. C.; Neufeld, R. J.. "Insulin-loaded nanoparticles are prepared by alginate ionotropic pre-gelation followed by chitosan polyelectrolyte complexation". Journal of Nanoscience and Nanotechnology 7 8 (2007): 2833-2841.
    10.1166/jnn.2007.609
  66. Reis, C.P.; Neufeld, R.J.; Ribeiro, A.J.; Veiga, F.. "Design of insulin-loaded alginate nanoparticles: Influence of the calcium ion on polymer gel matrix properties,Metoda za inkapsulaciju insulina u alginatne nanokapsule: Uticaj kalcijum jona na ponašanje dobijenih kapsula". Chemical Industry and Chemical Engineering Quarterly 12 1 (2006): 47-52. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947428315&partnerID=MN8TOARS.
    10.2298/CICEQ0601047R
  67. Urbano, A.P.A.; Ribeiro, A.J.; Veiga, F.. "Design of pectin beads for oral protein delivery,Dizajniranje pektinskih cestica za oralnu primenu proteina". Chemical Industry and Chemical Engineering Quarterly 12 1 (2006): 24-30. http://www.scopus.com/inward/record.url?eid=2-s2.0-84975725115&partnerID=MN8TOARS.
    10.2298/CICEQ0601024U
  68. Sarmento, Bruno; Ferreira, Dorningos; Veiga, Francisco; Ribeiro, Antonio. "Characterization of insulin-loaded alginate nanoparticles produced by ionotropic pre-gelation through DSC and FTIR studies". Carbohydrate Polymers 66 1 (2006): 1-7.
    10.1016/j.carbpol.2006.02.008
  69. Silva, CM; Ribeiro, AJ; Figueiredo, IV; Goncalves, AR; Veiga, F. "Alginate microspheres prepared by internal gelation: Development and effect on insulin stability". International Journal of Pharmaceutics 311 1-2 (2006): 1-10.
    10.1016/j.ijpharm.2005.10.050
  70. Sarmento, B; Martins, S; Ribeiro, A; Veiga, F; Neufeld, R; Ferreira, D. "Development and comparison of different nanoparticulate polyelectrolyte complexes as insulin carriers". International Journal of Peptide Research and Therapeutics 12 2 (2006): 131-138.
    10.1007/s10989-005-9010-3
  71. Sarmento, Bruno; Ribeiro, Antonio; Veiga, Francisco; Ferreira, Domingos. "Development and characterization of new insulin containing polysaccharide nanoparticles". Colloids and Surfaces B-Biointerfaces 53 2 (2006): 193-202.
    10.1016/j.colsurfb.2006.09.012
  72. Silva, Catarina M.; Veiga, Francisco; Ribeiro, Antonio J.; Zerrouk, Naima; Arnaud, Philippe. "Effect of chitosan-coated alginate microspheres on the permeability of Caco-2 cell monolayers". Drug Development and Industrial Pharmacy 32 9 (2006): 1079-1088.
    10.1080/03639040600735020
  73. Sarmento, Bruno; Ribeiro, Antonio; Veiga, Francisco; Ferreira, Domingos. "Development and validation of a rapid reversed-phase HPLC method for the determination of insulin from nanoparticulate systems". Biomedical Chromatography 20 9 (2006): 898-903.
    10.1002/bmc.616
  74. Silva, C.M.; Ribeiro, A.J.; Veiga, F.; Sousa, A.. "Insulin release from alginate microspheres reinforced with dextran sulfate,Kontrolisano otpuštanje insulina iz alginatnih cestica sa dekstran sulfatom". Chemical Industry and Chemical Engineering Quarterly 12 1 (2006): 40-46. http://www.scopus.com/inward/record.url?eid=2-s2.0-85012201855&partnerID=MN8TOARS.
    10.2298/CICEQ0601040S
  75. Pinto Reis, Catarina; Neufeld, Ronald J; Ribeiro, Antonio J; Veiga, Francisco. "Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles.". Nanomedicine : nanotechnology, biology, and medicine 2 1 (2006): 8-21.
    10.1016/j.nano.2005.12.003
  76. Silva, Catarina M.; Ribeiro, Antonio J.; Ferreira, Domingos; Veiga, Francisco. "Insulin encapsulation in reinforced alginate microspheres prepared by internal gelation". European Journal of Pharmaceutical Sciences 29 2 (2006): 148-159.
    10.1016/j.ejps.2006.06.008
  77. Reis, Catarina P.; Neufeld, Ronald J.; Vilela, Sandra; Ribeiro, Antonio J.; Veiga, Francisco. "Review and current status of emulsion/dispersion technology using an internal gelation process for the design of alginate particles". Journal of Microencapsulation 23 3 (2006): 245-257.
    10.1080/02652040500286086
  78. Pinto Reis, Catarina; Neufeld, Ronald J; Ribeiro, Antonio J; Veiga, Francisco. "Nanoencapsulation II. Biomedical applications and current status of peptide and protein nanoparticulate delivery systems.". Nanomedicine : nanotechnology, biology, and medicine 2 2 (2006): 53-65.
    10.1016/j.nano.2006.04.009
  79. Suva, C.M.; Ribeiro, A.J.; Figueiredo, M.; Ferreira, D.; Veigal, F.; Silva, CM; Ribeiro, AJ; et al. "Microencapsulation of hemoglobin in chitosan-coated alginate microspheres prepared by emulsification/internal gelation". AAPS Journal 7 4 (2005): E903-E913. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747115839&partnerID=MN8TOARS.
    10.1208/aapsj070488
  80. Ribeiro, AJ; Silva, C; Ferreira, D; Veiga, F. "Chitosan-reinforced alginate microspheres obtained through the emulsification/internal gelation technique". European Journal of Pharmaceutical Sciences 25 1 (2005): 31-40.
    10.1016/j.ejps.2005.01.016
  81. Silva, C.; Ribeiro, A.; Ferreira, D.; Veiga, F.. "Oral delivery systems for peptides and proteins: III. Application to insulin,Administração oral de peptídios e proteínas: III. Aplicação à insulina". Revista Brasileira de Ciencias Farmaceuticas/Brazilian Journal of Pharmaceutical Sciences 39 1 (2003): 21-40. http://www.scopus.com/inward/record.url?eid=2-s2.0-0043132428&partnerID=MN8TOARS.
  82. Silva, C.; Ribeiro, A.; Ferreira, D.; Veiga, F.. "Oral delivery system for peptides and proteins: II. Application of microencapsulation methods,Administração oral de peptídeos e proteinas: II. Aplicação de métodos de microencapsulação". Revista Brasileira de Ciencias Farmaceuticas/Brazilian Journal of Pharmaceutical Sciences 39 1 (2003): 1-20. http://www.scopus.com/inward/record.url?eid=2-s2.0-0041425278&partnerID=MN8TOARS.
  83. Silva, Catarina; Ribeiro, António; Ferreira, Domingos; Veiga, Francisco. "Administração oral de peptídios e proteínas: I. Estratégias gerais para aumento da biodisponibilidade oral". Revista Brasileira de Ciências Farmacêuticas 38 2 (2002): 125-140. http://dx.doi.org/10.1590/s1516-93322002000200002.
    10.1590/s1516-93322002000200002
  84. Silva, C.; Ribeiro, A.; Ferreira, D.; Veiga, F.. "Oral delivery system for peptides and proteins: I. Approaches to improve oral bioavailability,Administração oral de peptídios e proteínas: I. Estratégias gerais para aumento da biodisponibilidade oral". Revista Brasileira de Ciencias Farmaceuticas/Brazilian Journal of Pharmaceutical Sciences 38 2 (2002): 125-140. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036557792&partnerID=MN8TOARS.
  85. Ribeiro, A.J.; Arnaud, P.; Sousa Lobo, J.M.; Chaumeil, J.C.; Neufeld, R.J.. "Sustained release of organosulfur compounds from microencapsulated oily garlic extracts". Proceedings of the Controlled Release Society 26 (1999): 955-956. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032732687&partnerID=MN8TOARS.
  86. Ribeiro, AJ; Neufeld, RJ; Arnaud, P; Chaumeil, JC. "Microencapsulation of lipophilic drugs in chitosan-coated alginate microspheres". International Journal of Pharmaceutics 187 1 (1999): 115-123.
    10.1016/S0378-5173(99)00173-8
  87. Ribeiro, A.; Arnaud, P.; Frazao, S.; Venâncio, F.; Chaumeil, J.C.. "Development of vegetable extracts by microencapsulation". Journal of Microencapsulation 14 6 (1997): 735-742. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030827557&partnerID=MN8TOARS.
    10.3109/02652049709006823
Capítulo de livro
  1. Sequeira, Joana A.D.; Pereira, Irina; Ribeiro, António J.; Veiga, Francisco; Santos, Ana Cláudia. "Surface functionalization of PLGA nanoparticles for drug delivery". In Handbook of Functionalized Nanomaterials for Industrial Applications, 185-203. Elsevier, 2020.
    10.1016/b978-0-12-816787-8.00008-9
  2. Santos, Ana Cláudia; Caldas, Mariana; Pattekari, Pravin; Fontes Ribeiro, Carlos; Ribeiro, António José; Lvov, Yuri; Veiga, Francisco. "Layer-by-Layer coated drug-core nanoparticles as versatile delivery platforms". In Design and Development of New Nanocarriers, 595-635. Elsevier, 2018.
    10.1016/b978-0-12-813627-0.00016-8
  3. Pinto Reis, Catarina; Neufeld, Ronald J.; Veiga, Francisco; Ribeiro, Antonio J.. "Preparation of Drug-Loaded Polymeric Nanoparticles". In Nanomedicine in Cancer, 171-214. Pan Stanford, 2017.
    Publicado • 10.1201/b22358-7
  4. Ribeiro, António; Marlene Almeida Lopes; Raquel Monteiro; Francisco José de Baptista Veiga; Arnaud, Philippe; Gaia Cilloni. "Nanoparticles for oral delivery of insulin: facts, safety and diabetes-related inflammation concerns". In Nanomedicine for Inflammatory Diseases, editado por Lara L. Milane. Boca Raton, Estados Unidos: CRC Press Taylor & Francis Group, 2017.
    Publicado
  5. Ribeiro, António; Marlene Almeida Lopes; Francisco José de Baptista Veiga; Raquel Seiça; Lucio Mendes Cabral; Barbara Abrahim. "Alginate: Micro- and nanoparticles". In Encyclopedia of Biomedical Polymers and Polymeric Biomaterials. Reino Unido: Taylor & Francis, 2016.
    Publicado
  6. Ribeiro, Antonio J.; Seiça, Raquel; Veiga, Francisco. "Nanoparticles for Oral Delivery of Insulin". In Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment, 109-125. Springer Netherlands, 2013.
    Publicado • 10.1007/978-94-007-6010-3_4
  7. Ribeiro, António. "Design innovation for insulin delivery systems". In The bioartificial Endocrine Pancreas and Other Biohybrid Therapies, 557-585. Kerala, Índia: Transworld Research Network, 2009.
    Publicado
Livro
  1. Sequeira, J.A.D.; Santos, A.C.; Serra, J.; Veiga, F.; Ribeiro, A.J.; Sequeira, Joana A.D.; Santos, Ana C.; et al. Poly(lactic-co-glycolic acid) (PLGA) matrix implants. Elsevier. 2018.
    10.1016/b978-0-12-813665-2.00010-7
Resumo em conferência
  1. Ribeiro, António; Francisco José de Baptista Veiga; Joana Margarida de Almeida Dias Duarte Sequeira. "Using Nanoprecipitation to Produce Insulin – PLGA Nanoparticles". Trabalho apresentado em BioNanoMed 2017 - 8th International Congress Nanotechnology in Medicine & Biology,, Krems, 2017.
    Publicado
Tese / Dissertação
  1. Blanco, Bruna Martins. "Qual o contributo da fitoterapia no âmbito da alopecia androgenética?". Mestrado, 2018. http://hdl.handle.net/10316/84716.
  2. Barbosa, Joana Rafaela Sousa. "Simultaneous administration of insulin and GLP-1 agonists. Technologically possible?". Mestrado, 2017. http://hdl.handle.net/10316/83770.
  3. Tavares, Sara Mariana Oliveira Mendonça Matos. "Internship Report and Monograph "The Role of Pharmacist managing Type 2 Diabetic Patients Undergoing GLP-1 RAs Therapies".". Mestrado, 2017. http://hdl.handle.net/10316/83644.
  4. Oliveira, Gonçalo Varajão Barbosa Cruz de. "Community Pharmacy and Hospital Pharmacy Internship Reports and Monograph "Counseling for Androgenetic Alopecia - The Pharmacist's Role"". Mestrado, 2017. http://hdl.handle.net/10316/83659.

Propriedade Intelectual

Patente
  1. Ribeiro, J António. 2008. "Processo de produção e isolamento de micro- e nanopartículas poliméricas contendo macromoléculas de natureza hidrofílica e termolábil". Portugal.
    Concedida/Emitida
  2. Ribeiro, J António. 2007. "ORAL SUBMICRON PARTICLE DELIVERY SYSTEM FOR PROTEINS AND PROCESS FOR ITS PRODUCTION". Portugal.
    Pendente
Pedido provisório de patente
  1. 2016. "COMPOSIÇÃO DE UM SISTEMA BIOPOLIMÉRICO PARA VEICULAÇÃO ORAL DE FÁRMACOS PEPTÍDICOS".
    Protegido
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2019/12/09 Technological development of polymeric implants for extended release of drugs 2nd Middle East Pharmacy and Pharmaceutical Conference
(Dubai, Emiratos Árabes Unidos)
2018/06/06 Micro et nanoencapsulation de macromolecules Laboratoire de Pharmacie Galénique, Faculté de Pharmacie, Université Paris V
(Paris, França)
2018/06/05 Layer-by-layer assembly for oral delivery of resveratrol nanocores
Latef - Laboratório de Tecnologia Farmacêutica, Faculdade de Ciências Farmacêuticas, Universidade Estadual de Campinas (Campinas, Brasil)
2017/10/27 Layer-by-layer self-assembly nanoparticles designed for resveratrol delivery 13th International Conference and Exhibition on Advanced Materials and Nanotechnology,
(Osaka, Japão)
2017/07/04 Biodistribution and pharmacological evaluation of insulin-loaded biopolymer--based nanoparticles
Pharmaceutical Nanotechnology and Chemical Microsystems (NAMI) (Helsinki, Finlândia)
2017/06/09 Nanoparticles for oral delivery of insulin
Department of Drug Sciences, University of Parma (Parma, Itália)
2017/02/21 Nanoencapsulation du resveratrol à travers la technique Layer-by-Layer
Laboratoire de Pharmacie Galénique, Faculté de Pharmacie, Université Paris V (Paris, França)
2016/06/17 Dual chitosan/albumin-coated alginate/dextran sulfate nanoparticles: overcoming barriers to oral delivery of insulin
Unité de Technologies Chimiques et Génétiques pour la Santé (UTCBS), (Paris, França)
2015/11/18 Nanoencapsulation de l’insuline par émulsification/gélification interne
Laboratoire de Pharmacie Galénique, Faculté de Pharmacie, Université Paris V, (Paris, França)
2015/04/11 A nanotecnologia na administração oral da insulina II Encontro Estratégico em Ciências Farmacêuticas, II Seminário Ibero Americano de P & D de Medicamentos, I Simpósio Internacional de Farmácia Clínica,
(Teresina, Brasil)
2013/09/25 Intestinal absorption of insulin nanoparticles: contribution of M cells
Seminari del FaBiT, Dipartimento di Farmacia i Biotecnologie, Università di Bologna (Bologna, Itália)
2013/06 Nanodelivery systems to fight cancer Therapeutic Targets for Cell Death in Cancer, “Pharmacy Summer School" Roma
(Roma, Itália)
2013/04/09 O impacto da nanoencapsulação nos ensaios clínicos
Faculdade de Ciências Farmacêuticas da Universidade de São Paulo (São Paulo, Brasil)
2013/04/04 Administração oral da insulina I Encontro Estratégico em Ciências Farmacêuticas, I Seminário Ibero Americano de P & D de Medicamentos
(Teresina, Brasil)
2012/09/18 M cells: effect on intestinal uptake of insulin nanoparticle
Faculty of Pharmacy, University of Helsinki (Helsinki, Finlândia)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2020 - Atual Enhanced Quality by Design Approach to the Development of an Oral Prolonged Release Formulation
Orientador
 Pharmaceutical Development (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018 - Atual Gastro resistant polymer-coated lipid nanoparticles for oral delivery of insulin.
Orientador
 Pharmaceutical Technology (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2017/03/01 - Atual Incorporação de insulina em nanopartículas preparadas por nanoprecipitação: Desenho fatorial, caracterização e manutenção da atividade biológica.
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2016 - Atual Preparation and characterization of insulin-loaded nanoparticles made by inotropic gelation
Orientador
 Drug delivery (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2014 - Atual Development of a non-viral vector for treatment for neurodegenerative diseases
Coorientador
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013 - Atual Nanoencapsulation of Ibuprofen in poly-(caprolactone)-based nanoparticles.
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2010 - Atual Antioxidant-loaded polysaccharide nanoparticles for application in aqualculture
Coorientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2009 - Atual Freeze-drying recovering of alginate microparticles made by emulsification/internal gelation
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2017/09 - 2018/08 Adsorção de um fragmento de anticorpo a nanopartículas poliméricas para aumentar a absorção intestinal da insulina.
Coorientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2013/09/01 - 2018/01/25 Layer-by-layer nanoparticles to improve the bioavailability of resveratrol .
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2013/09/01 - 2017/07/16 Effect of biopolymers based nanoparticles on enhancing insulin permeation through intestinal epithelium.
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2017 - 2017 Coacervados de polifosfatos para a libertação prolongada de antiséticos orais
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2017 - 2017 Coacervados de polifosfatos como veículos para liberação controlada de fármacos
Coorientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2017 - 2017 Desenvolvimento de sílica mesoporosa como veículos para liberação controlada de fármacos.
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2017 - 2017 Interaction of biopolymer-based nanoparticles with their storage medium: the influence of pH and ionic force on nanoparticle's size and zeta potential
Orientador
 Drug delivery (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2017 - 2017 Dialysis purification of biopolymer-based nanoparticles
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2016/04 - 2016/12 Nanoparticules de resveratrol/PLGA pour réduire la toxicité notamment hépatique de le doxorubicine.
Coorientador
Unité de Technologies Chimiques et Biologiques pour la Santé, França
2016 - 2016 Desenvolvimento de formulações mucoadesivas para xerostomia.
Coorientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2016 - 2016 Síntese de nanopartículas à base de goma de cajueiro e quitosana modificadas para aplicação em sistemas de liberação de insulina.
Coorientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2016 - 2016 Desenvolvimento de sistemas põliméricós nanoestruturados à base de goma de caju modificada para administração oral da insulina.
Coorientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2016 - 2016 New insights on aqueous stability of nanoparticles made of polysaccharides for oral delivery of insulin.
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2016 - 2016 New research approaches for Type 1 Diabetes
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2014/01 - 2014/12 Bionanopartículas como modelo de estudo para as interações com "Macrophage phagocytic system”
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2011/01/01 - 2014/09 Desenvolvimento tecnológico de nanopartículas de alginato e sulfato dextrano contendo insulina revestidas com quitosano e albumina a partir de nanoemulsões.
Coorientador
Universidade Federal do Rio de Janeiro Faculdade de Farmácia, Brasil
2014 - 2014 Nanoencapsulação de fármacos peptídicos recorrendo à goma de cajueiro
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2014 - 2014 Probing size distribution of albumin/chitosan coated alginate/dextran sulfate nanoparticles made by emulsification/internal gelation in simulated gastrointestinal conditions
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2013 - 2014 Radioactive labeling of NP with albumin to study the biodistribution
Orientador
 Pharmaceutical biotechnology (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2009/09/01 - 2013/07/10 Alginate nanoparticles prepared by microemulsification internal gelation for DNA delivery.
Coorientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2012 - 2012 Improving the solubility of Ibuprofen through its nano encapsulation in biopolymers
Orientador
 Pharmaceutical Technology (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2012 - 2012 Obtenção de Nanopartículas de Goma do Cajueiro Acetilada com Tamoxifeno no Tratamento de Queloide
Coorientador
 Materials science (Mestrado)
Universidade Federal do Piauí, Brasil
2006/09/01 - 2011/07/08 Physiological action of insulin-loaded nanoparticles by quantification of hepatic production and gluconeogenesis.
Coorientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2004/01/01 - 2008/03/28 Encapsulation of peptidic drugs through emulsification/internal gelation method.
Coorientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2004/01/01 - 2007/10/18 Improvement of peptidic drugs oral availability through their encapsulation in polyelectrolytes complexes.
Coorientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2003/09/01 - 2007/04/17 Aumento da biodisponibilidade oral de fármacos peptídicos recorrendo à encapsulação em alginato e quitosano
Coorientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2001 - 2003 Microencapsulation of peptidic drugs in pectin-based miroparticles by emulsification/internal gelation
Coorientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2001 - 2001 Comparative study of drugs release from microparticles before and after its incorporation in matrix tablets
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2018 - Atual Journal of Pharmacy Practice and Education iMedPub LTD
2018 - Atual Nanomaterial Chemistry and Technology Edelweiss Publications
2016 - Atual Current Nanoscience Bentham Science

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2018 - Atual Projects evaluation Agência para o Investimento e Comércio Externo de Portugal , Portugal
2018 - Atual Research projects evaluation European Science Foundation, França
2016 - Atual Projects evaluation Agência da Inovação, Portugal
2019 - 2020 Research project evaluation Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung, Suiça
Distinções

Título

2016 Visiting Schoolar
Université de Paris Faculté des Sciences Pharmaceutiques et Biologiques, França
2013 Invited Researcher (Universidades do Pernambuco e do Piauí)
Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brasil

Outra distinção

2009 Bluepharma Award 2009
Bluepharma, Portugal
2007 Most cited paper
2007 Best poster presentation
Ordem dos Farmaceuticos, Portugal
2006 BES Inovation Prize
Banco Espírito Santo e Comercial de Lisboa, Portugal
2005 Most cited Paper
Elsevier BV, Países Baixos