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Currently I am a junior researcher in the Cytoskeleton Dynamics lab of Dr. Ana Carvalho at i3S. My primary research interests involve the development of a comprehensive understanding of how the regulation of the actomyosin cytoskeleton during cell and tissue morphogenesis contribute to human diseases. My academic training and research experience have provided me with an excellent background in multiple biology disciplines such as molecular biology, biochemistry, bioinformatics, microbiology and cell biology. In 2011, I gradated my PhD in Biochemisty in the Hong Kong Polytechnic University (HKPU) and completed a doctoral thesis project in the labs with Prof. Kwok-Yin Wong (Vice-President of HKPU) and Prof. Ruben Abaygan (UCSD, USA) on the discovery of novel molecules that inhibit cytokinesis in antibiotic-resistant bacteria. During my PhD and initial Postdoctoral studies, I worked in close collaboration with organic chemists, biologists, and computational chemists to identify novel antibacterial compounds. This work resulted in three first author publications and two second author papers and opened new lines of research in the lab. Another great achievement in my PhD study was to receive the Eli Lilly Asia Outstanding Graduate Thesis Award in 2011. In order to further expand my methodological horizons and broaden my scientific knowledge in the field of cytokinesis, I joined the Cytoskeletal Dynamics lab of Dr. Ana Carvalho at IBMC/i3S in 2013 to mechanistically study actomyosin driven processes such as the contractile ring in embryonic cytokinesis using the nematode C. elegans as model system. Of particular my current interest is to explore how actin filament crosslinkers contribute to the mechanical properties of the actomyosin network during cytokinesis and other cellular contexts such as gonad development, musclar organization and vulva morphogenesis. During the last eleven years, I had the opportunity to develop essential advanced skills on this organism such as microinjection, gene editing using CRISPR/Cas9 and MosSCI techniques, high-resolution live imaging, and in vitro biochemical assays, which are essential to perform my investigations and to establish future independent research lines. I was also involved in collaborative projects with other research groups. I promoted my research and networking by attending reputed international meetings where I gave two oral presentations at the ASCB meeting, USA in 2017 and Paris Cytoskeleton Day in 2021. I improved my lab supervision and mentoring skills by co-supervising two PhD, three MSc students and one techician with Dr. Ana Carvalho.
Identificação

Identificação pessoal

Nome completo
Fung Yi Chan

Nomes de citação

  • Chan, Fung-Yi

Identificadores de autor

Ciência ID
1910-FE69-D261
ORCID iD
0000-0002-4770-9768

Endereços de correio eletrónico

  • fung.chan@ibmc.up.pt (Profissional)

Moradas

  • INSTITUTE FOR MOLECULAR AND CELL BIOLOGY. I3S, Rua Alfredo Allen, 208, 4200-135, PORTO, Porto, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Exatas - Ciências da Computação e da Informação - Bioinformática
Formação
Grau Classificação
2011/10/29
Concluído
Doctor of Philosophy in the Department of Applied Biology and Chemical Technology (Doutoramento)
Especialização em Biochemistry
The Hong Kong Polytechnic University, Hong Kong
"Discovery of Novel Inhibitors of the Bacterial Cell Division Protein FtsZ by Computational Drug Screening Coupled with Bioassays" (TESE/DISSERTAÇÃO)
Approved with Distinction
2006/12/01
Concluído
BSc (Hons) Chemical Technology (Bacharelato)
The Hong Kong Polytechnic University, Hong Kong
"Alkene Cyclopropanation Catalyzed by Haltermen Iron Porphyrin: Participation of Organic Bases" (TESE/DISSERTAÇÃO)
17 with the first-class honor
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2019/01/01 - 2024/12/31 Investigador Contratado (Investigação) Instituto de Investigação e Inovação da Universidade do Porto, Portugal
INSTITUTO DE INVESTIGAÇÃO E INOVAÇÃO EM SAÚDE DA UNIVERSIDADE DO PORTO (I3S), Portugal
2013/02/15 - 2018/12/31 Pós-doutorado (Investigação) Fundação para a Ciência e a Tecnologia, Portugal
Instituto de Biologia Molecular e Celular - IBMC, Portugal
2012/01/01 - 2012/07/10 Pós-doutorado (Investigação) University of California San Diego School of Medicine, Estados Unidos
University of California San Diego, Estados Unidos
2011/07/01 - 2011/12/31 Assistente de Investigação (carreira) (Investigação) the scripps research institute, Estados Unidos
The Scripps Research Institute, Estados Unidos

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2006/09/01 - 2011/10/29 PhD student under the supervision of Prof. Kwok-Yin Wong Title: Discovery of novel inhibitors of the bacterial cell division protein FtsZ by computational drug screening coupled with bioassays. Sponso The Hong Kong Polytechnic University, Hong Kong
The Hong Kong Polytechnic University, Hong Kong
(...)
2009/01/01 - 2010/04/30 Exchange PhD student in Ruben Abagyan's laboratory University of California San Diego, Estados Unidos
University of California San Diego, Estados Unidos
(...)
Projetos

Bolsa

Designação Financiadores
2022/01/01 - 2023/12/31 Actin cross-linker interplay in sarcomeres and impact in muscle disease
Investigador
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2015/07 - 2020/06 ACTOMYO
Investigador Pós-doutorado
European Research Council (ERC), Bélgica
European Research Council (ERC)
Concluído
2014/12/01 - 2018/12/31 Functional dissection of actin filament network organization and dynamics during cytokinesis
SFRH/BPD/93528/2013
Investigador Pós-doutorado
Fundação para a Ciência e a Tecnologia
Concluído
2013/05 - 2018/12 Functional dissection of branched and non-branched actin filament networks during cytokinesis
SFRH/BI/52111/2013
Investigador Pós-doutorado
Fundação para a Ciência e a Tecnologia, Portugal
N/A
Concluído
2014/01/15 - 2014/11/30 Functional dissection of branched and non-branched actin filament networks during cytokinesis
PEst-LA041304-BPD
Investigador Pós-doutorado
INSTITUTE FOR MOLECULAR AND CELL BIOLOGY. I3S, Portugal
Concluído
2013/05/15 - 2013/12/31 Functional dissection of branched and non-branched actin filament networks during cytokinesis
SFRH/BI/52111/2013
Investigador Pós-doutorado
Institute for Molecular and Cell Biology, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2013/05/01 - 2013/12/31 EXAMINING THE CONTRIBUTION OF DIFFERENT ACTIN FILAMENT POPULATIONS TO CYTOKINESIS
SFRH/BI/52111/2013
Fundação para a Ciência e a Tecnologia
Concluído
2012/01/01 - 2012/07/10 In silico structure-based design of novel inhibitors of bacterial cell division proteins and cell wall biosynthesis proteins
4-BBX3
Investigador Pós-doutorado
The Hong Kong Polytechnic University, Hong Kong

University of California San Diego Department of Pharmacology, Estados Unidos
Concluído
2011/07/01 - 2011/12/31 Structural studies on autophagy proteins
GM092740
Investigador
The Scripps Research Institute, Estados Unidos
National Institutes of Health
Concluído

Projeto

Designação Financiadores
2019/01/01 - 2024/12/31 Functional dissection of actin filament network organization and dynamics during cytokinesis
503 828 360
Investigador
Instituto de Biologia Molecular e Celular, Portugal
Em curso
2019/01/01 - 2019/12/31 Institute for Research and Innovation in Health Sciences
UID/BIM/04293/2019
LA/P/0070/2020
Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Outro

Designação Financiadores
2006/09/01 - 2011/10/29 Discovery of novel inhibitors of the bacterial cell division protein FtsZ by computational drug screening coupled with bioassays.
4-BBX3
Bolseiro de Doutoramento
The Hong Kong Polytechnic University, Hong Kong
Concluído
Produções

Publicações

Artigo em revista
  1. Lebedev, Mikhail; Chan, Fung-Yi; Lochner, Anna; Bellessem, Jennifer; Osório, Daniel S.; Rackles, Elisabeth; Mikeladze-Dvali, Tamara; Carvalho, Ana Xavier; Zanin, Esther. Autor correspondente: Zanin, Esther. "Anillin forms linear structures and facilitates furrow ingression after septin and formin depletion". Cell Reports 42 9 (2023): 113076. http://dx.doi.org/10.1016/j.celrep.2023.113076.
    Publicado • 10.1016/j.celrep.2023.113076
  2. Trevor J. Barker; Chan, Fung-Yi; Ana X. Carvalho; Meera V. Sundaram. Autor correspondente: Meera V. Sundaram. "Apical-basal polarity of the spectrin cytoskeleton in the C. elegans vulva". microPublication Biology (2023):
    Acesso aberto • Publicado • 10.17912/micropub.biology.000863
  3. Ana Marta Silva; Fung-Yi Chan; Michael J. Norman; Ana Filipa Sobral; Esther Zanin; Reto Gassmann; Julio Monti Belmonte; Ana Xavier Carvalho. "ß-heavy-spectrin stabilizes the constricting contractile ring during cytokinesis". Journal of Cell Biology (2023): https://doi.org/10.1083/jcb.202202024.
    10.1083/jcb.202202024
  4. Sobral, Ana Filipa, First co-author; Chan, Fung-Yi, First co-author; Norman, Michael J.; Osório, Daniel S.; Dias, Ana Beatriz; Ferreira, Vanessa; Barbosa, Daniel J.; et al. "Plastin and spectrin cooperate to stabilize the actomyosin cortex during cytokinesis". Current Biology 31 24 (2021): 5415-5428.e10. http://dx.doi.org/10.1016/j.cub.2021.09.055.
    Acesso aberto • Aceite para publicação • 10.1016/j.cub.2021.09.055
  5. Leite, Joana; Chan, Fung-Yi; Osório, Daniel S.; Saramago, Joana; Sobral, Ana F.; Silva, Ana M.; Gassmann, Reto; Carvalho, Ana X.. "Equatorial Non-muscle Myosin II and Plastin Cooperate to Align and Compact F-actin Bundles in the Cytokinetic Ring". Frontiers in Cell and Developmental Biology 8 (2020): http://dx.doi.org/10.3389/fcell.2020.573393.
    10.3389/fcell.2020.573393
  6. Osório, Daniel S. First co-author; Chan, Fung-Yi First co-author; Saramago, Joana First co-author; Leite, Joana; Silva, Ana M.; Sobral, Ana F.; Gassmann, Reto; Xavier Carvalho, Ana. "Crosslinking activity of non-muscle myosin II is not sufficient for embryonic cytokinesis in C. elegans". Development (2019): dev.179150-dev.179150. https://doi.org/10.1242/dev.179150.
    10.1242/dev.179150
  7. Chan, Fung-Yi; Silva, Ana M.; Saramago, Joana; Pereira-Sousa, Joana; Brighton, Hailey E.; Pereira, Marisa; Oegema, Karen; Gassmann, Reto; Carvalho, Ana Xavier. "The ARP2/3 complex prevents excessive formin activity during cytokinesis". Molecular Biology of the Cell 30 1 (2019): 96-107. http://dx.doi.org/10.1091/mbc.e18-07-0471.
    10.1091/mbc.e18-07-0471
  8. Osorio DS; Chan FY; Saramago J; Leite J; Silva AM; Sobral AF; Gassmann R; Xavier Carvalho A. "Flow-independent accumulation of motor-competent non-muscle myosin II in the contractile ring is essential for cytokinesis". bioRxiv (2018): https://doi.org/10.1101/333286.
    10.1101/333286
  9. Vieira N; Bessa C; Rodrigues AJ; Marques P; Chan FY; de Carvalho AX; Correia-Neves M; Sousa N. "Sorting nexin 3 mutation impairs development and neuronal function in Caenorhabditis elegans.". Cellular and molecular life sciences : CMLS (2017): http://europepmc.org/abstract/med/29196797.
    10.1007/s00018-017-2719-2
  10. Chan, Kin-Fai; Sun, Ning; Yan, Siu-Cheong; Wong, Iris L. K.; Lui, Hok-Kiu; Cheung, Kwan-Choi; Yuan, Jian; et al. "Efficient synthesis of amine-linked 2,4,6-rrisubstituted pyrimidines as a new class of bacterial FtsZ inhibitors". ACS Omega 2 10 (2017): 7281-7292. http://dx.doi.org/10.1021/acsomega.7b00701.
    10.1021/acsomega.7b00701
  11. Sun, Ning; Lu, Yu-Jing; Chan, Fung-Yi; Du, Ruo-Lan; Zheng, Yuan-yuan; Zhang, Kun; So, Lok-Yan; et al. "A thiazole orange derivative targeting the bacterial protein FtsZ shows potent antibacterial activity". Frontiers in Microbiology 8 (2017): http://dx.doi.org/10.3389/fmicb.2017.00855.
    10.3389/fmicb.2017.00855
  12. Chan, Fung-Yi; Sun, Ning; Leung, Yun-Chung; Wong, Kwok-Yin. "Antimicrobial activity of a quinuclidine-based FtsZ inhibitor and its synergistic potential with ß-lactam antibiotics". The Journal of Antibiotics 68 4 (2014): 253-258. http://dx.doi.org/10.1038/ja.2014.140.
    10.1038/ja.2014.140
  13. Wang, Yong; Chan, Fung-Yi; Sun, Ning; Lui, Hok-Kiu; So, Pui-Kin; Yan, Siu-Cheong; Chan, Kin-Fai; et al. "Structure-based design, synthesis, and biological evaluation of isatin derivatives as potential glycosyltransferase inhibitors". Chemical Biology & Drug Design 84 6 (2014): 685-696. http://dx.doi.org/10.1111/cbdd.12361.
    10.1111/cbdd.12361
  14. Sun, Ning; Chan, Fung-Yi; Lu, Yu-Jing; Neves, Marco A. C.; Lui, Hok-Kiu; Wang, Yong; Chow, Ka-Yan; et al. "Rational design of berberine-based FtsZ inhibitors with broad-spectrum antibacterial activity". PLoS ONE 9 5 (2014): e97514. http://dx.doi.org/10.1371/journal.pone.0097514.
    10.1371/journal.pone.0097514
  15. Chan, Fung-Yi; Sun, Ning; Neves, Marco A. C.; Lam, Polo Chun-Hung; Chung, Wai-Hong; Wong, Lai-King; Chow, Ho-Yin; et al. "Identification of a new class of FtsZ inhibitors by structure-based design and in vitro screening". Journal of Chemical Information and Modeling 53 8 (2013): 2131-2140. http://dx.doi.org/10.1021/ci400203f.
    10.1021/ci400203f
  16. Chan, Fung-Yi; Neves, Marco A. C.; Sun, Ning; Tsang, Man-Wah; Leung, Yun-Chung; Chan, Tak-Hang; Abagyan, Ruben; Wong, Kwok-Yin. "Validation of the ampC ß-lactamase binding site and identification of inhibitors with novel scaffolds". Journal of Chemical Information and Modeling 52 5 (2012): 1367-1375. http://dx.doi.org/10.1021/ci300068m.
    10.1021/ci300068m
  17. Lu, Yu-Jing; Yan, Siu-Cheong; Chan, Fung-Yi; Zou, Lan; Chung, Wai-Hong; Wong, Wing-Leung; Qiu, Bin; et al. "Benzothiazole-substituted benzofuroquinolinium dye: a selective switch-on fluorescent probe for G-quadruplex". Chemical Communications 47 17 (2011): 4971. http://dx.doi.org/10.1039/c1cc00020a.
    10.1039/c1cc00020a
  18. Ma, Dik-Lung; Lai, Tat-Shing; Chan, Fung-Yi; Chung, Wai-Hong; Abagyan, R.; Leung, Yun-Chung; Wong, Kwok-Yin. "Discovery of a drug-like G-quadruplex binding ligand by high-throughput docking". ChemMedChem 3 6 (2008): 881-884. http://dx.doi.org/10.1002/cmdc.200700342.
    10.1002/cmdc.200700342
  19. Ma, Dik-Lung; Wong, Wing-Leung; Chung, Wai-Hong; Chan, Fung-Yi; So, Pui-Kin; Lai, Tat-Shing; Zhou, Zhong-Yuan; Leung, Yun-Chung; Wong, Kwok-Yin. "A highly selective luminescent switch-on probe for histidine/histidine-rich proteins and its application in protein staining". Angewandte Chemie International Edition 47 20 (2008): 3735-3739. http://dx.doi.org/10.1002/anie.200705319.
    10.1002/anie.200705319
  20. Lai, Tat-Shing; Chan, Fung-Yi; So, Pui-Kin; Ma, Dik-Lung; Wong, Kwok-Yin; Che, Chi-Ming. "Alkene cyclopropanation catalyzed by Halterman iron porphyrin: participation of organic bases as axial ligands". Dalton Transactions 40 (2006): 4845. http://dx.doi.org/10.1039/b606757c.
    10.1039/b606757c
Capítulo de livro
  1. Chan, Fung Yi; Silva, Ana Marta; Carvalho, Ana Xavier. "Using the four-cell C. elegans embryo to study contractile ring dynamics during cytokinesis". In Methods in Molecular Biology, 297-325. Springer US, 2019.
    10.1007/978-1-0716-0219-5_18
Poster em conferência
  1. Chan, Fung-Yi; Osório, Daniel S.; Gassmann, Reto; Carvalho, Ana X.. "Two distinct myosins contribute to early vs late stages of spermatheca organogenesis".
    10.3389/fcell.2020.573393
  2. Chan, Fung-Yi; Osório, Daniel S.; Gassmann, Reto; Ana Costa Xavier de Carvalho. "Two distinct myosins contribute to early vs late stages of spermatheca organogenesis". Trabalho apresentado em Forces across scales, 2024.
  3. Chan, Fung-Yi; Osorio, Daniel S; Gassmann, Reto; Carvalho, Ana X.. "Two distinct myosins contribute to early vs late stages of spermatheca organogenesis". Trabalho apresentado em 24th International C. elegans Conference, 2023.
  4. Leite, Joana; Chan, Fung-Yi; Osório, Daniel S.; Saramago, Joana; Sobral, Ana F.; Silva, Ana M.; Gassmann, Reto; Carvalho, Ana X.. "Equatorial non-musclemyosin II and plastin cooperate to align and compact F-actin bundles in the cytokinetic ring". Trabalho apresentado em Cell Bio Virtual 2020 | An Online ASCB|EMBO Meeting, 2020.
  5. Adriana Manuela da Silva Mendes; Chan, Fung-Yi; Ana Costa Xavier de Carvalho. Autor correspondente: Chan, Fung-Yi. "Unveil the role of actin on KRAS-induced autophagy in colorectal cancer using C. elegans as an in vivo model". Trabalho apresentado em I3S annual meeting, 2018.
  6. Chan, Fung-Yi; Silva, Ana-Marta; Ana Costa Xavier de Carvalho. "Crosstalk between the ARP2/3 complex and formin ensures timely cytokinesis". Trabalho apresentado em EMBO workshop: C. elegans development, cell biology and gene expression, 2018.
  7. Chan, Fung-Yi; Ana Costa Xavier de Carvalho. "Functional dissection of branched and non-branched actin filament network during cytokinesis". Trabalho apresentado em I3S annual meeting, 2016.
  8. Osório, Daniel Sampaio; Saramago, J.; Chan, Fung-Yi; Pereira, LM; Carvalho, AX. "Myosin-actin interplays in C. elegans embryonic cytokinesis". Trabalho apresentado em EMBL meeting "Actin in Action: From Molecules to Cellular Functions", 2016.
  9. Chan, Fung; Ana Xavier de Carvalho. "Functional dissection of branched and non-branched actin filament network during cytokinesis". Trabalho apresentado em ASCB annual meeting, 2015.
  10. Chan, Fung-Yi. "Functional dissection of branched and non-branched actin filament network during cytokinesis". Trabalho apresentado em Berlin C. elegans meeting, 2014.
  11. Chan, Fung-Yi. "Structure-based validation of AmpC ß-lactamase for the design of non-covalent inhibitors". Trabalho apresentado em The 243rd American Chemistry Society National Exposition, 2012.
  12. Chan, Fung-Yi. "High throughput screening of new AmpC ß-lactamase inhibitors by docking". Trabalho apresentado em 1st Singapore-Hong Kong Bilateral Graduate Student Congress, 2009.
  13. Chan, Fung-Yi. "Discovery of drug-Like hit of G-quadruplex binding ligand by high-throughput docking". Trabalho apresentado em ISCO 2008 Congress International Society for Cellular Oncology, 2008.
Pré-impressão
  1. Mikhail Lebedev; Fung-Yi Chan; Jennifer Bellessem; Daniel S. Osório; Elisabeth Rackles; Tamara Mikeladze-Dvali; Ana X. Carvalho; Esther Zanin. "Anillin forms linear structures and facilitates furrow ingression after septin and formin depletion". 2022. https://doi.org/10.1101/2022.12.22.521621.
    10.1101/2022.12.22.521621

Propriedade Intelectual

Patente
  1. Wong, Kwok-Yin; Ma, Dik-Lung; Wong, Wing-Leung; Chung, Wai-Hong; Chan, Fung-Yi. 2012. "Luminescent protein staining". Estados Unidos.
    Concedida/Emitida
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/11/17 Two distinct myosins contribute to early vs late stages of spermatheca organogenesis 10th I3S Annual Meeting
Instituto de Inovação e Investigação em Saúde (Póvoa de Varzim, Portugal)
2021/11/17 Plastin and ß-Heavy-spectrin cooperate to stabilize the actomyosin cortex during cytokinesis Paris Cytoskeleton Day
Institut Pasteur (paris, França)
2017/12/02 Functional dissection of the Arp2/3 complex and the branched actin filament network during C. elegans cytokinesis. ASCB EMBO meeting 2017
American Society for Cell Biology (Estados Unidos)
2016/11/03 Functional dissection of branched and non-branched actin filament network during cytokinesis I3S annual meeting
Universidade do Porto Instituto de Biologia Molecular e Celular (Portugal)
2014/07/02 Interplay of actin regulators during cytokinesis. PostDoc Seminar Series
Universidade do Porto Instituto de Biologia Molecular e Celular (Portugal)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2024/01/01 - Atual Dissecting the roles of Anillin in tissue morphogenesis
Coorientador
Programa Doutoral em Ciências Biomédicas (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/09/01 - Atual Investigating Formin's contribution to abscission
Coorientador
Mestrado em Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/09/01 - 2022/06/13 Functionalities and interplay of actin-filament crosslinkers in vivo.
Coorientador
Ciências Biomédicas (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/09/01 - 2020/12/17 Dissecting formin´s molecular mechanisms of action during embryonic cell division
Coorientador
Mestrado em Bioquímica da Universidade do Porto (FCUP/ICBAS) (Master) (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal
2017/09/01 - 2018/10/31 Unveil the role of actin on KRAS induced autophagy in colorectal cancer, using Caenorhabditis elegans as an in vivo model
Coorientador
Mestrado em Genética Molecular (Mestrado)
Universidade do Minho, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2022/01/06 - Atual Attended the International Zoom Seminars on Developmental Mechanics, which provide a forum to share recent findings and facilitate collaborations at the interfaces between molecular, cell, and developmental biology and biophysics, mathematics, and bioengineering. Seminars take place every week.
Seminário
the International Zoom Seminars on Developmental Mechanics
Tel Aviv University, Israel
2024/04/11 - 2024/04/14 Participated in the event of University of Porto Fair. In this year, i3S was present with a stand and many activities. The priority was to promote the Institute, reinforcing the position of i3S as the largest research institute of the University. This large event bring the University of Porto "out of doors" so that the participants were able to contact with all the areas of knowledge of the University.
Exposição
Mostra UP 2024
Universidade do Porto, Portugal
2024/03/06 - 2024/03/09 Attended the 4-days conference of “Forces across scales” that focused on mechanobiology, a multidisciplinary area of research that explores how mechanical forces interact with biological systems, influencing cellular behavior, tissue development, and disease progression. This meeting bridged different scales and processes, bringing together researchers from diverse disciplines, such as biology, biophysics, bioinformatics, and bioengineering to stimulate knowledge exchange and disseminate cutting-edge research findings.
Conferência
Forces across scales
INSTITUTO DE INVESTIGAÇÃO E INOVAÇÃO EM SAÚDE DA UNIVERSIDADE DO PORTO (I3S), Portugal
2024/02/02 - 2024/02/02 Attended the 3rd Master Open Day dedicated to undergraduate students currently searching for their end-of-degree internship. This event will offer them the opportunity to talk to current students and researchers, who could provide very helpful advice at this crucial junction of their academic and professional careers. Our lab also joined this exhibition to show our wonderful working C. elegans model and promote our research interests and look for the potential master student(s) who is interested in our lab.
Exposição
3rd Master Open Day
INSTITUTO DE INVESTIGAÇÃO E INOVAÇÃO EM SAÚDE DA UNIVERSIDADE DO PORTO (I3S), Portugal
2023/12/04 - 2023/12/05 Attended the 2-day workshop on Scientific Writing: How to streamline the process of writing a scientific paper
Oficina (workshop)
Workshop on Scientific Writing: How to streamline the process of writing a scientific paper
INSTITUTO DE INVESTIGAÇÃO E INOVAÇÃO EM SAÚDE DA UNIVERSIDADE DO PORTO (I3S), Portugal
2023/06/13 - 2023/06/29 Attended the 4-day workshop of Research Project Management where included the following essential concepts to manage a research project -- An introduction to project management and equip participants with basic skills in managing research projects; From research question to project description; Scheduling: milestones, tasks, and charts; Time management: managing yourself and the work; Team management: the right person for the right job; Risks: identification and management; Financial issues; Project communication, dissemination, and exploitation.
Oficina (workshop)
Research Project Management, 3rd edition
INSTITUTO DE INVESTIGAÇÃO E INOVAÇÃO EM SAÚDE DA UNIVERSIDADE DO PORTO (I3S), Portugal
2023/06/24 - 2023/06/28 Attended the 5-days conference of international C. elegans conference at scotland, which is the premier meeting for C. elegans researchers. Hundreds of presentations cover the full diversity of C. elegans investigations, including genetics, molecular biology, cell biology, development, immunology, physiology, neuroscience, evolution, and more
Conferência
24th International C. elegans Conference
Genetics Society of America, Estados Unidos
2023/02/23 - 2023/02/24 Attended the seminars on the 9th edition of the Molecular and Cell Biology Symposium Science - ´´everything, everywhere all at once´´. This symposium will bring together international speakers from the three main lines of research of i3S (Cancer, Host Interaction and Response, and Neurobiology and Neurologic Disorders), lectures, and poster sessions from PhD students. We are delighted to be back to face-to-face meetings and look forward to bringing our community together for an
Conferência
9th McBiology Symposium
INSTITUTO DE INVESTIGAÇÃO E INOVAÇÃO EM SAÚDE DA UNIVERSIDADE DO PORTO (I3S), Portugal
2023/02/03 - 2023/02/03 Attended the 2nd Master Open Day dedicated to undergraduate students currently searching for their end-of-degree internship. This event will offer them the opportunity to talk to current students and researchers, who could provide very helpful advice at this crucial junction of their academic and professional careers. Our lab also joined this exhibition to show our wonderful working C. elegans model and promote our research studies and look for the potential master student(s) who is interested in our lab.
Exposição
2nd MSc Open Day
INSTITUTE FOR MOLECULAR AND CELL BIOLOGY. I3S, Portugal
2022/02/25 - 2022/02/25 Attended the 1st Master Open Day dedicated to undergraduate students currently searching for their end-of-degree internship. This event will offer them the opportunity to talk to current students and researchers, who could provide very helpful advice at this crucial junction of their academic and professional careers. Our lab also joined this exhibition to show our wonderful working C. elegans model and promote our research studies and look for the potential master student(s) who is interested in our lab.
Exposição
1st MSc Open Day
INSTITUTE FOR MOLECULAR AND CELL BIOLOGY. I3S, Portugal
2021/09/21 - 2021/09/21 Participated in European night of Investigators 2021. This exhibition was to promote the national scientific and technological development and create an enviroment that stimulates fruitful scientific production and its transfer to the clinic. i3S is one of organizers in this exhibition to promote our scientisitic works to public at night. We had a chance to show our wonderful working C. elegans model and our scientific works to the students and public.
Exposição
European night of Investigators 2021
INSTITUTO DE INVESTIGAÇÃO E INOVAÇÃO EM SAÚDE DA UNIVERSIDADE DO PORTO (I3S), Portugal
2020/06/03 - 2020/06/04 Attended the seminars on Cell & Developmental Biology Virtual Meeting
Conferência
Cell & Developmental Biology Virtual Meeting 2020
Labroots, Inc, Estados Unidos
2019/11/13 - 2019/11/15 Attended the workshop-Batch analysis and macro development in ImageJ/Fiji: going beyond the basics
Oficina (workshop)
Batch analysis and macro development in ImageJ/Fiji: going beyond the basics
INSTITUTE FOR MOLECULAR AND CELL BIOLOGY. I3S, Portugal
2017/07/01 - 2017/07/01 Attended the seminars on Forces in Cell Biology
Oficina (workshop)
Forces in Cell Biology
INSTITUTE FOR MOLECULAR AND CELL BIOLOGY. I3S, Portugal
2017/04/19 - 2017/04/21 Attended the workshop where the concepts and techniques will be explored directly in the MATLAB environment. MATLAB is a well-established tool in scientific and technical computing, with key advantages such as being extremely versatile/powerful and easy to learn. This course provided the all basic materials to use MATLAB software in the context of scientific data analysis and image processing (quantification). It was very useful for us to treat and analyze the data obtained from our live-imaging experiments.
Oficina (workshop)
Introduction to data analysis and image processing with MATLAB
INSTITUTO DE INVESTIGAÇÃO E INOVAÇÃO EM SAÚDE DA UNIVERSIDADE DO PORTO (I3S), Portugal
2017/03/17 - 2017/03/17 Attended the First Retreat of the Cancer integrative program
Encontro
First Retreat of the Cancer integrative program
INSTITUTE FOR MOLECULAR AND CELL BIOLOGY. I3S, Portugal
2017/02/09 - 2017/02/10 Attended the GENiE high content screening workshop
Oficina (workshop)
GENiE high content screening workshop
INSTITUTE FOR MOLECULAR AND CELL BIOLOGY. I3S, Portugal
2014/04/11 - 2014/04/16 This workshop covered the ImageJ plugin programming and the usability of ImageJ and ICY softwares for microscopy image analysis.
Oficina (workshop)
Working with ImageJ and ICY: Hands on image analysis for microscopy
Instituto de Biologia Molecular e Celular - IBMC, Portugal

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2023/11/24 Thesis title: Understanding the nucleation, assembly and dynamics of axonal actin rings
Arguente principal
Maria Leonor Pereira Moura (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2021/11/29 Interview about our lab and an article we published in Current Biology: Sobral and Chan et al., 2021 "Plastin and spectrin cooperate to stabilize the actomyosin cortex during cytokinesis" Notícias Universidade do Porto
2021/11/19 Interview about our lab and an article we published in Current Biology: Sobral and Chan et al., 2021 "Plastin and spectrin cooperate to stabilize the actomyosin cortex during cytokinesis" Publico
2020/01/13 Interview about our lab and an article we published in Development: Osorio et al., 2019 "Crosslinking activity of non-muscle myosin II is not sufficient for embryonic cytokinesis in C. elegans" Development/The people behind the papers

Membro de associação

Nome da associação Tipo de participação
2023/03/08 - Atual Genetics Society of America Scientific member
2017/08 - 2020/12 American Society for Cell Biology Scientific member

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2024/01/01 - Atual Friday noon seminar
Membro
INSTITUTE FOR MOLECULAR AND CELL BIOLOGY. I3S, Portugal

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2023/06/26 - 2023/06/26 Participated as a poster judge at the 2023 International C. elegans Conference. It was very valuable work to judge five student posters where I selected the best poster presenter to compete the poster awards. In addition, I provided some useful comments for their scientific development and project improvement. Genetics Society of America, Estados Unidos
2017/12/03 - 2017/12/03 Participated as a poster judge to judge 10 undergraduate student posters at the 2017 ASCB|EMBO meeting in Philadelphia, United State. American Society for Cell Biology, Estados Unidos
Distinções

Prémio

2011 2nd prize of Eli Lilly Asia Outstanding Graduate Thesis Award
Eli Lilly Asia, China
2003 First prize of the 15th Chemistry Olympiad for Hong Kong Tertiary

Outra distinção

2006 First class honors of Bachelor Degree of Science in Chemical Technology
The Hong Kong Polytechnic University, Hong Kong
2005 Dean's Honours List of three-top score students
The Hong Kong Polytechnic University, Hong Kong
2004 Dean's Honours List of three-top score students
The Hong Kong Polytechnic University, Hong Kong