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Ana Rita Bento got her master degree in Biomedical Engineering, with specialisation in Neurosciences at the Faculty of Sciences and Technology of University of Coimbra, in 2009. During that time, she worked as a researcher at the Centre for Neuroscience and Cell Biology (CNC), in the field of Neurogenesis and Brain Repair. In 2012, Ana Rita moved to Porto to start her PhD at the Faculty of Engineering of University of Porto. During her PhD, she worked at the NanoBiomaterials for Targeted Therapies group at the Institute for Research and Innovation in Health (i3s) and at the Institute of Biomedical Engineering (INEB), University of Porto. Ana Rita worked as a Junior Researcher at the Cell and Differentiation group at the Institute of Biomedicine (iBiMED), University of Aveiro, Portugal.
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Identificação

Identificação pessoal

Nome completo
Ana Rita Bento

Nomes de citação

  • Bento, Ana Rita

Identificadores de autor

Ciência ID
2617-A555-6E79
ORCID iD
0000-0002-9578-8237
Scopus Author Id
57192699335

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais
  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências
  • Ciências Naturais - Ciências Biológicas - Biologia Celular

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Português (Idioma materno)
Formação
Grau Classificação
2012/09 - 2018/05/09
Concluído
 Biomedical Engineering (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
"Improving neurite outgrowth in 3D hydrogel matrices by mimicking cell receptor-ECM interactions occurring in neurogenic niches: an engineering approach to develop more efficient neural stem cell hydrogel carriers" (TESE/DISSERTAÇÃO)
 Aprovado
2004 - 2009/09/03
Concluído
 Integrated Master in Biomedical Engineering (Mestrado integrado)
Especialização em Neurosciences
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"The effect of methamphetamine on subventricular zone neurogenesis: cell death, proliferation and differentiation/ O efeito da metanfetamina na neurogénese da zona subventricular: morte celular, proliferação e diferenciação" (TESE/DISSERTAÇÃO)
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/07/19 - 2020/09/02 Pós-doutorado (Investigação) Universidade de Aveiro, Portugal
Universidade de Aveiro Instituto de Biomedicina, Portugal
2012/09/19 - 2018/05/09 Investigador (Investigação) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2010/08/02 - 2011/07/29 Assistente de Investigação (carreira) (Investigação) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2008/09 - 2010/07 Estagiário de Investigação (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/07/21 - 2008/09/21 Estagiário de Investigação (Investigação) Universidade de Coimbra, Portugal
University of Coimbra - Institute of Biomedical Research in Light and Image , Portugal
Produções

Publicações

Artigo em conferência
  1. Ana Rita Bento; Sofia Baptista; Joao O. Malva; Ana Paula Silva; Fabienne Agasse. "The effect of methamphetamine on subventricular zone neurogenesis: Cell death, proliferation and differentiation". 2012.
    10.1109/enbeng.2012.6331378
  2. Bento, A.R.; Baptista, S.; Malva, J.O.; Silva, A.P.; Agasse, F.. "The effect of methamphetamine on subventricular zone neurogenesis: Cell death, proliferation and differentiation". 2012.
    10.1109/ENBENG.2012.6331378
Artigo em revista
  1. Ana R. Bento; Pedro Quelhas; Maria J. Oliveira; Ana P. Pêgo; Isabel F. Amaral. "Three-dimensional culture of single embryonic stem-derived neural/stem progenitor cells in fibrin hydrogels: neuronal network formation and matrix remodelling". Journal of Tissue Engineering and Regenerative Medicine 11 12 (2017): 3494-3507. https://doi.org/10.1002/term.2262.
    10.1002/term.2262
  2. Bento, Ana. "Fibrin functionalization with synthetic adhesive ligands interacting with a6ß1 integrin receptor enhance neurite outgrowth of embryonic stem cell-derived neural stem/progenitors.". Acta biomaterialia (2017): http://europepmc.org/abstract/med/28694236.
    10.1016/j.actbio.2017.07.013
  3. Bento, Ana. "Fibrin hydrogels functionalized with alpha6beta1 ligands for transplantation of neural stem/progenitor cells". Frontiers in Bioengineering and Biotechnology (2016): http://dx.doi.org/10.3389/conf.fbioe.2016.01.00908.
    10.3389/conf.fbioe.2016.01.00908
  4. Almeida IF; Pinto AS; Monteiro C; Monteiro H; Belo L; Fernandes J; Bento AR; et al. "Protective effect of C. sativa leaf extract against UV mediated-DNA damage in a human keratinocyte cell line.". (2015): http://europepmc.org/abstract/med/25686820.
    10.1016/j.jphotobiol.2015.01.010
  5. Bento, Ana. "Poster Presentations". Journal of Tissue Engineering and Regenerative Medicine 8 (2014): 207-518. http://dx.doi.org/10.1002/term.1932.
    10.1002/term.1932
  6. Bento, Ana. "Oral Presentations". Journal of Tissue Engineering and Regenerative Medicine (2014): http://dx.doi.org/10.1002/term.1931.
    10.1002/term.1931
  7. Baptista S; Bento AR; Gonçalves J; Bernardino L; Summavielle T; Lobo A; Fontes-Ribeiro C; et al. "Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures.". (2012): http://europepmc.org/abstract/med/22381583.
    10.1016/j.neuropharm.2012.02.015
  8. Baptista, S.; Bento, A.R.; Gonçalves, J.; Bernardino, L.; Summavielle, T.; Lobo, A.; Fontes-Ribeiro, C.; et al. "Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures.". Neuropharmacology 62 7 (2012): 2413-2423. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871869687&partnerID=MN8TOARS.
  9. Bento AR; Baptista S; Malva JO; Silva AP; Agasse F. "Methamphetamine exerts toxic effects on subventricular zone stem/progenitor cells and inhibits neuronal differentiation.". (2011): http://europepmc.org/abstract/med/21453012.
    10.1089/rej.2010.1109
  10. Ana Cristina Santos; Cláudia Matos; Ana Rita Bento; Eliana Murteira; Filipe Leite; Marco Pinto; Micaela Cunha; et al. "Effect of nuclear magnetic resonance fields in peritoneal macrophages". Revista Brasileira de Engenharia Biomédica 27 E (2011): 15-19. http://dx.doi.org/10.4322/rbeb.2012.010.
    10.4322/rbeb.2012.010
  11. Bento, Ana. "Methamphetamine is toxic for murine dentate progenitor cell cultures". Frontiers in Neuroscience (2009): http://dx.doi.org/10.3389/conf.neuro.01.2009.11.048.
    10.3389/conf.neuro.01.2009.11.048
  12. Rita-Bento Ana. "Methamphetamine exerts toxic effects in murine subventricular zone cell cultures". Frontiers in Neuroscience 3 (2009): http://dx.doi.org/10.3389/conf.neuro.01.2009.11.050.
    10.3389/conf.neuro.01.2009.11.050
Tese / Dissertação
  1. Ana Rita Das Neves Lagarto Bento. "Improving neurite outgrowth in 3D hydrogel matrices by mimicking cell receptor-ECM interactions occurring in neurogenic niches: an engineering approach to develop more efficient neural stem cell hydrogel carriers". Doutoramento, 2018. https://repositorio-aberto.up.pt/handle/10216/112151.
  2. Bento, Ana Rita das Neves Lagarto. "The effect of methamphetamine on subventricular zone neurogenesis: cell death, proliferation and differentiation/ O efeito da metanfetamina na neurogénese da zona subventricular: morte celular, proliferação e diferenciação". Mestrado, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2009. http://hdl.handle.net/10316/12194.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2018/02/28 Improving neurite outgrowth in 3D hydrogel matrices towards the development of more efficient neural stem cell hydrogel carriers. Young Scientists Seminar
Institute for Research and Innovation in Health (i3S), University of Porto (Porto, Portugal)
2017/10/27 HYD1-conjugated fibrin hydrogels promote cell migration of embryonic stem-derived neural/stem progenitor cells in vitro and are permissive to axonal regeneration in vivo. 5th Symposium in Applied Bioimaging
Institute for Research and Innovation in Health (i3S), University of Porto (Porto, Portugal)
2017/06/19 Functionalization of fibrin hydrogels with a6ß1 integrin-binding adhesive peptides for delivery of pluripotent stem cell-derived neural stem/progenitors. Advanced Summer School, Interrogations at the Biointerface - Research/Clinical Interface at the Spine
Institute for Research and Innovation in Health (i3S), University of Porto (Porto, Portugal)
2016/11/03 HYD1-conjugated fibrin hydrogels promote cell migration of embryonic stem-derived neural/stem progenitor cells in vitro and are permissive to axonal regeneration in vivo. 5th i3S Scientific Retreat
Institute for Research and Innovation in Health (i3S), University of Porto (Póvoa do Varzim, Portugal)

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2019/10/11 - 2019/10/11 Fostering Responsible Conduct of Research
Oficina (workshop)
Universidade de Aveiro, Portugal
2018/03/03 - 2018/03/04 Essential Project Management for Students
Oficina (workshop)
 Essential Project Management for Students - Associação Portuguesa de Gestão e Engenharia Industrial (APGEI)
Universidade do Porto, Portugal
2016/06/22 - 2016/06/25 Communication (poster): "Three-dimensional culture of single embryonic stem-derived neural/stem progenitor cells in fibrin hydrogels: neuronal network formation and matrix remodelling.", San Francisco, CA USA.
Congresso
 International Society for Stem Cell Research (ISSCR) Annual Meeting
International Society for Stem Cell Research (ISSCR), Estados Unidos
2015/06/01 - 2015/06/04 Course on High Content Screening and Image Analysis for Biosciences
Oficina (workshop)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2014/06/10 - 2014/06/12 Communication (poster): "In vitro cell behaviour of dissociated embryonic stem-derived neural stem cells in fibrin hydrogels.", Genoa, Italy.
Conferência
 Meeting of the Tissue Engineering and Regenerative Medicine International Society European Chapter Meeting (TERMIS-EU)
Tissue Engineering and Regenerative Medicine International Society, Inc. (TERMIS), Estados Unidos
2014/04/09 - 2014/04/09 Communication (poster): "Cell-matrix constructs based on embryonic stem cell-derived neural stem/progenitor cells embedded in fibrin hydrogels for central nervous system regeneration. ", Porto, Portugal.
Conferência
 4th Meeting of FMUC PhD Students
Universidade do Porto Faculdade de Medicina, Portugal
2014/02 - 2014/04 Introductory Course in Laboratory Animal Science following FELASA Cat. B recommendations
Oficina (workshop)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2013/05/30 - 2013/06/01 Communication (poster): "Optimization of cell culture parameters for the 3-D culture of single embryonic stem cell-derived neural stem cells in fibrin." Luso, Portugal
Conferência
 13th Meeting of the Portuguese Society for Neurosciences
2012/02/23 - 2012/02/25 Communication (poster): "The effect of methamphetamine on subventricular zone neurogenesis: cell death, proliferation and differentiation." Coimbra, Portugal
Congresso
 2nd Portuguese BioEngineering Meeting, IEEE EMBS Portuguese Chapter
2011/05/22 - 2011/05/24 Communication (poster): "Understanding the role of Nrf2/ARE signalling in the cellular defence against iron toxicity.", Vancouver, BC, Canada
Congresso
 International BioIron Society (IBIS) Annual Meeting
2011/05/05 - 2011/05/06 Communication (poster): "Understanding the role of Nrf2/ARE signalling in the cellular defence against iron toxicity." Póvoa do Varzim, Portugal
Congresso
 2nd i3S Scientific Retreat
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2010/12/14 - 2010/12/15 Communication (poster): "A role for Nrf2/ARE signalling in the cellular defence against iron cytotoxicity." Porto, Portugal
Congresso
 XVII Congresso Nacional de Bioquímica
2009/06/04 - 2009/06/06 Communication (poster): "Methamphetamine exerts toxic effects in murine subventricular zone cell cultures." Braga, Portugal
Conferência
 11th Meeting of the Portuguese Society for Neurosciences

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2017 - Atual Journal of Tissue Engineering and Regenerative Medicine

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2019/10/09 - 2019/10/09 Lecturer of the class "Development of an engineered hydrogel to be used in neural stem cell-based therapies", in the discipline "Cell Therapy and Regenerative Medicine" of the course in Biomedical Sciences (degree, 3rd year). Licenciatura em Ciências Biomédicas (Licenciatura) Universidade de Aveiro Departamento de Ciências Médicas, Portugal

Membro de associação

Nome da associação Tipo de participação
2009 - Atual Portuguese Society for Neuroscience (SPN)
2018 - 2019 Associação Portuguesa de Gestão e Engenharia Industrial (APGEI)
2016 - 2017 International Society for Stem Cell Research (ISSCR)
2014 - 2015 Tissue Engineering and Regenerative Medicine International Society (TERMIS)
Distinções

Prémio

2014 Best poster at the 4th Meeting of PhD Students of the Faculty of Medicine of University of Porto
Universidade do Porto Faculdade de Medicina, Portugal
2012 FCT individual grant - "Bio-inspired hydrogels for neural stem cell transplantation: a combinatorial therapeutic approach to promote regeneration in the spinal cord" (SFRH/BD/86200/2012).
Fundação para a Ciência e a Tecnologia, Portugal