| Artigo em revista |
- Flávia Barbosa; Joana Araújo; Virgínia M. F. Gonçalves; Andreia Palmeira; Andrea Cunha; Patrícia M. A. Silva; Carla Fernandes;
et al. "Evaluation of Antitumor Activity of Xanthones Conjugated with Amino Acids". International Journal of Molecular
Sciences (2024): https://doi.org/10.3390/ijms25042121.
10.3390/ijms25042121
- Resende, Diana I. S. P.; Durães, Fernando; Zubarioglu, Sidika; Freitas-Silva, Joana; Szemerédi, Nikoletta; Pinto, Madalena;
Pinto, Eugénia; et al. "Antibacterial Potential of Symmetrical Twin-Drug 3,6-Diaminoxanthones". Pharmaceuticals 17
2 (2024): 209. http://dx.doi.org/10.3390/ph17020209.
10.3390/ph17020209
- Daniela Pereira; Madalena Pinto; Joana R. Almeida; Marta Correia-da-Silva; Honorina Cidade. "The Role of Natural and Synthetic
Flavonoids in the Prevention of Marine Biofouling". Marine Drugs (2024): https://doi.org/10.3390/md22020077.
10.3390/md22020077
- Joana Moreira; Patrícia M. A. Silva; Eliseba Castro; Lucília Saraiva; Madalena Pinto; Hassan Bousbaa; Honorina Cidade. "BP-M345
as a Basis for the Discovery of New Diarylpentanoids with Promising Antimitotic Activity". International Journal of Molecular
Sciences (2024): https://doi.org/10.3390/ijms25031691.
10.3390/ijms25031691
- Ana Alves; Ana Margarida Silva; Claúdia Nunes; Sara Cravo; Salette Reis; Madalena Pinto; Emília Sousa; et al. "The Synthesis
and Characterization of a Delivery System Based on Polymersomes and a Xanthone with Inhibitory Activity in Glioblastoma".
Life (2024): https://doi.org/10.3390/life14010132.
10.3390/life14010132
- Ana Alves; Ana M. Silva; Joana Moreira; Claúdia Nunes; Salette Reis; Madalena Pinto; Honorina Cidade; et al. "Polymersomes
for Sustained Delivery of a Chalcone Derivative Targeting Glioblastoma Cells". Brain Sciences (2024): https://doi.org/10.3390/brainsci14010082.
10.3390/brainsci14010082
- Joana Moreira; Joana B. Loureiro; Danilo Correia; Andreia Palmeira; Madalena M. Pinto; Lucília Saraiva; Honorina Cidade. "Structure–Activity
Relationship Studies of Chalcones and Diarylpentanoids with Antitumor Activity: Potency and Selectivity Optimization". Pharmaceuticals
(2023): https://doi.org/10.3390/ph16101354.
10.3390/ph16101354
- Coutinho, Ana J.; Pinheiro, Marina; Neves, Ana R.; Pinto, Madalena. "Therapeutic Potential of Genistein: Preclinical Studies,
ClinicalEvidence, and Nanotechnology Application". Current Medicinal Chemistry 30 22 (2023): 2480-2517. http://dx.doi.org/10.2174/0929867329666221004124800.
10.2174/0929867329666221004124800
- Vieira, Sara F.; Araújo, Joana; Gonçalves, Virgínia M. F.; Fernandes, Carla; Pinto, Madalena; Ferreira, Helena; Neves, Nuno
M.; Tiritan, Maria Elizabeth. "Synthesis and Anti-Inflammatory Evaluation of a Library of Chiral Derivatives of Xanthones
Conjugated with Proteinogenic Amino Acids". International Journal of Molecular Sciences 24 12 (2023): 10357. http://dx.doi.org/10.3390/ijms241210357.
10.3390/ijms241210357
- Joana Moreira; Patrícia M. A. Silva; Matilde Barros; Lucília Saraiva; Madalena Pinto; Hassan Bousbaa; Honorina Cidade. "Discovery
of a New Chalcone-Trimethoxycinnamide Hybrid with Antimitotic Effect: Design, Synthesis, and Structure—Activity Relationship
Studies". Pharmaceuticals (2023): https://doi.org/10.3390/ph16060879.
10.3390/ph16060879
- Mariana C. Almeida; Nikoletta Szemerédi; Fernando Durães; Solida Long; Diana I. S. P. Resende; Paulo Martins da Costa; Madalena
Pinto; Gabriella Spengler; Emília Sousa. "Effect of Indole-Containing Pyrazino[2,1-b]quinazoline-3,6-diones in the Virulence
of Resistant Bacteria". Antibiotics (2023): https://doi.org/10.3390/antibiotics12050922.
10.3390/antibiotics12050922
- José X. Soares; Inês Afonso; Adaleta Omerbasic; Daniela R. P. Loureiro; Madalena M. M. Pinto; Carlos M. M. Afonso. "The Chemical
Space of Marine Antibacterials: Diphenyl Ethers, Benzophenones, Xanthones, and Anthraquinones". Molecules (2023): https://doi.org/10.3390/molecules28104073.
10.3390/molecules28104073
- Vilas-Boas, Cátia; Silva, Elisabete R.; Resende, Diana; Pereira, Beatriz; Sousa, Gonçalo; Pinto, Madalena; Almeida, Joana
R.; Correia-da-Silva, Marta; Sousa, Emília. Autor correspondente: Correia-da-Silva, Marta. "3,4-Dioxygenated xanthones as
antifouling additives for marine coatings: in silico studies, seawater solubility, degradability, leaching, and antifouling
performance". Environmental Science and Pollution Research 30 26 (2023): 68987-68997. http://dx.doi.org/10.1007/s11356-023-26899-1.
10.1007/s11356-023-26899-1
- Bruno Horta; Joana Freitas-Silva; Jani Silva; Francisca Dias; Ana Luísa Teixeira; Rui Medeiros; Honorina Cidade; Madalena
Pinto; Fátima Cerqueira. "Antitumor Effect of Chalcone Derivatives against Human Prostate (LNCaP and PC-3), Cervix HPV-Positive
(HeLa) and Lymphocyte (Jurkat) Cell Lines and Their Effect on Macrophage Functions". Molecules (2023): https://doi.org/10.3390/molecules28052159.
10.3390/molecules28052159
- Carla Fernandes; Ricardo Ribeiro; Madalena Pinto; Anake Kijjoa. "Absolute Stereochemistry Determination of Bioactive Marine-Derived
Cyclopeptides by Liquid Chromatography Methods: An Update Review (2018–2022)". Molecules (2023): https://doi.org/10.3390/molecules28020615.
10.3390/molecules28020615
- Miguel Maia; Fernando Durães; Diana I. S. P. Resende; Nikoletta Szemerédi; Luís Gales; Paulo Martins-da-Costa; Madalena Pinto;
Gabriella Spengler; Emília Sousa. "Xanthene Derivatives Targeting Bacterial Efflux Pumps, Quorum-Sensing, and Biofilm Formation".
Drugs and Drug Candidates (2022): https://doi.org/10.3390/ddc1010004.
10.3390/ddc1010004
- Daniela Pereira; Fernando Durães; Nikoletta Szemerédi; Joana Freitas-da-Silva; Eugénia Pinto; Paulo Martins-da-Costa; Madalena
Pinto; et al. "New Chalcone–Triazole Hybrids with Promising Antimicrobial Activity in Multidrug Resistance Strains". International
Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms232214291.
10.3390/ijms232214291
- Marialucia Gallorini; Simone Carradori; Diana I. S. P. Resende; Luciano Saso; Alessia Ricci; Andreia Palmeira; Amelia Cataldi;
Madalena Pinto; Emília Sousa. "Natural and Synthetic Xanthone Derivatives Counteract Oxidative Stress via Nrf2 Modulation
in Inflamed Human Macrophages". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms232113319.
10.3390/ijms232113319
- Fernandes, Carla; Lima, Rita; Pinto, Madalena; Tiritan, Maria Elizabeth. "Chromatographic supports for enantioselective liquid
chromatography: Evolution and innovative trends". Journal of Chromatography A 1684 (2022): 463555. http://dx.doi.org/10.1016/j.chroma.2022.463555.
10.1016/j.chroma.2022.463555
- Joana Cardoso; Joana Freitas-Silva; Fernando Durães; Diogo Teixeira Carvalho; Luís Gales; Madalena Pinto; Emília Sousa; Eugénia
Pinto. "Antifungal Activity of a Library of Aminothioxanthones". Antibiotics (2022): https://doi.org/10.3390/antibiotics11111488.
10.3390/antibiotics11111488
- Joana Moreira; Lucilia Saraiva; Madalena M. Pinto; Honorina Cidade. "Bioactive Diarylpentanoids: Insights into the Biological
Effects beyond Antitumor Activity and Structure–Activity Relationships". Molecules (2022): https://doi.org/10.3390/molecules27196340.
10.3390/molecules27196340
- Rita Neves, Ana; Vilas Boas, Cátia; Gonçalves, Catarina; Vasconcelos, Vitor; Pinto, Madalena; Silva, Elisabete R.; Sousa,
Emília; Almeida, Joana R.; Correia-da-Silva, Marta. Autor correspondente: Correia-da-Silva, Marta. "Gallic acid derivatives
as inhibitors of mussel (Mytilus galloprovincialis) larval settlement: Lead optimization, biological evaluation and use in
antifouling coatings". Bioorganic Chemistry 126 (2022): 105911. http://dx.doi.org/10.1016/j.bioorg.2022.105911.
10.1016/j.bioorg.2022.105911
- Cátia Vilas-Boas; Virgínia Gonçalves; Paolo De Marco; Emília Sousa; Madalena Pinto; Elisabete R. Silva; Maria Elizabeth Tiritan;
Marta Correia-da-Silva. "Quantification of a Sulfated Marine-Inspired Antifouling Compound in Several Aqueous Matrices: Biodegradation
Studies and Leaching Assays from Polydimethylsiloxane Coatings". Marine Drugs (2022): https://doi.org/10.3390/md20090548.
10.3390/md20090548
- José X. Soares; Álvaro Santos; Carla Fernandes; Madalena M. M. Pinto. "Liquid Chromatography on the Different Methods for
the Determination of Lipophilicity: An Essential Analytical Tool in Medicinal Chemistry". Chemosensors (2022): https://doi.org/10.3390/chemosensors10080340.
10.3390/chemosensors10080340
- Ana R. Neves; Luciana C. Gomes; Sara I. Faria; João Sousa; Raquel Ruivo; Inês Páscoa; Madalena Pinto; et al. "Antifouling
Marine Coatings with a Potentially Safer and Sustainable Synthetic Polyphenolic Derivative". Marine Drugs (2022): https://doi.org/10.3390/md20080507.
10.3390/md20080507
- Gomes, Ana Sara; Correia, Alexandra; Rahikkala, Antti; Mäkilä, Ermei; Pinto, Madalena; Sousa, Emília; Salonen, Jarno; Saraiva,
Lucília; Santos, Hélder A.. Autor correspondente: Santos, Hélder A.. "Folic acid-mesoporous silicon nanoparticles enhance
the anticancer activity of the p73-activating small molecule LEM2". International Journal of Pharmaceutics 624 (2022):
121959. http://dx.doi.org/10.1016/j.ijpharm.2022.121959.
10.1016/j.ijpharm.2022.121959
- Sandra Barreiro; Bárbara Silva; Solida Long; Madalena Pinto; Fernando Remião; Emília Sousa; Renata Silva. "Fiscalin Derivatives
as Potential Neuroprotective Agents". Pharmaceutics (2022): https://doi.org/10.3390/pharmaceutics14071456.
10.3390/pharmaceutics14071456
- Moreira, Joana; Durães, Fernando; Freitas-Silva, Joana; Szemerédi, Nikoletta; Resende, Diana I.S.P.; Pinto, Eugenia; da Costa,
Paulo Martins; et al. Autor correspondente: Sousa, Emília. "New diarylpentanoids and chalcones as potential antimicrobial
adjuvants". Bioorganic & Medicinal Chemistry Letters 67 (2022): 128743. http://dx.doi.org/10.1016/j.bmcl.2022.128743.
10.1016/j.bmcl.2022.128743
- Lima, Rita; Fernandes, Carla; Pinto, Madalena. Autor correspondente: Fernandes, Carla. "Molecular modifications, biological
activities, and applications of chitosan and derivatives: A recent update". Chirality 34 9 (2022): 1166-1190. http://dx.doi.org/10.1002/chir.23477.
10.1002/chir.23477
- Ana Jesus; Fernando Durães; Nikoletta Szemerédi; Joana Freitas-Silva; Paulo Martins da Costa; Eugénia Pinto; Madalena Pinto;
et al. "BDDE-Inspired Chalcone Derivatives to Fight Bacterial and Fungal Infections". Marine Drugs 20 5 (2022): 315-315.
https://doi.org/10.3390/md20050315.
10.3390/md20050315
- José X. Soares; Daniela R. P. Loureiro; Ana Laura Dias; Salete Reis; Madalena M. M. Pinto; Carlos M. M. Afonso. "Bioactive
Marine Xanthones: A Review". Marine Drugs (2022): https://doi.org/10.3390/md20010058.
10.3390/md20010058
- Long, Solida; Duarte, Denise; Carvalho, Carla; Oliveira, Rafael; Santarém, Nuno; Palmeira, Andreia; Resende, Diana I. S. P.;
et al. "Indole-Containing Pyrazino[2,1-b]quinazoline-3,6-diones Active against Plasmodium and Trypanosomatids". (2022): http://hdl.handle.net/10362/134564.
https://doi.org/10.1021/acsmedchemlett.1c00589
- Daniela Pereira; Madalena Pinto; Marta Correia-da-Silva; Honorina Cidade. "Recent Advances in Bioactive Flavonoid Hybrids
Linked by 1,2,3-Triazole Ring Obtained by Click Chemistry". Molecules (2021): https://doi.org/10.3390/molecules27010230.
10.3390/molecules27010230
- Cláudia Pinto; Honorina Cidade; Madalena Pinto; Maria Elizabeth Tiritan. "Chiral Flavonoids as Antitumor Agents". Pharmaceuticals
(2021): https://doi.org/10.3390/ph14121267.
10.3390/ph14121267
- Vilas-Boas, Cátia; Neves, Ana Rita; Carvalhal, Francisca; Pereira, Sandra; Calhorda, Maria José; Vasconcelos, Vitor; Pinto,
Madalena; et al. Autor correspondente: Correia-da-Silva, Marta. "Multidimensional characterization of a new antifouling xanthone:
Structure-activity relationship, environmental compatibility, and immobilization in marine coatings". Ecotoxicology and
Environmental Safety 228 (2021): 112970. http://dx.doi.org/10.1016/j.ecoenv.2021.112970.
10.1016/j.ecoenv.2021.112970
- Ana Rita Neves; Daniela Pereira; Catarina Gonçalves; Joana Cardoso; Eugénia Pinto; Vitor Vasconcelos; Madalena Pinto; et al.
"Natural Benzo/Acetophenones as Leads for New Synthetic Acetophenone Hybrids Containing a 1,2,3-Triazole Ring as Potential
Antifouling Agents". Marine Drugs (2021): https://doi.org/10.3390/md19120682.
10.3390/md19120682
- Diana I. S. P. Resende; Joana R. Almeida; Sandra Pereira; Alexandre Campos; Agostinho Lemos; Jeffrey E. Plowman; Ancy Thomas;
et al. "From Natural Xanthones to Synthetic C-1 Aminated 3,4-Dioxygenated Xanthones as Optimized Antifouling Agents". Marine
Drugs 19 11 (2021): 638-638. https://doi.org/10.3390/md19110638.
10.3390/md19110638
- Durães, Fernando; Cravo, Sara; Freitas-Silva, Joana; Szemerédi, Nikoletta; Martins-da-Costa, Paulo; Pinto, Eugénia; Tiritan,
Maria Elizabeth; et al. Autor correspondente: Pinto, Madalena. "Enantioselectivity of Chiral Derivatives of Xanthones in Virulence
Effects of Resistant Bacteria". Pharmaceuticals 14 11 (2021): 1141. http://dx.doi.org/10.3390/ph14111141.
10.3390/ph14111141
- Pedro Novais; Patrícia Silva; Joana Moreira; Andreia Palmeira; Isabel Amorim; Madalena M. M. Pinto; Honorina Cidade; Hassan
Bousbaa. "BP-M345, a New Diarylpentanoid with Promising Antimitotic Activity". Molecules (2021): https://www.mdpi.com/1420-3049/26/23/7139.
10.3390/molecules26237139
- Carla Fernandes; Joana Teixeira; Madalena M. M. Pinto; Maria Elizabeth Tiritan. "Strategies for Preparation of Chiral Stationary
Phases: Progress on Coating and Immobilization Methods". Molecules (2021): https://doi.org/10.3390/molecules26185477.
10.3390/molecules26185477
- Fernando Durães; Nikoletta Szemerédi; Decha Kumla; Madalena Pinto; Anake Kijjoa; Gabriella Spengler; Emília Sousa. "Metabolites
from Marine-Derived Fungi as Potential Antimicrobial Adjuvants". Marine Drugs (2021): https://doi.org/10.3390/md19090475.
10.3390/md19090475
- Long, Solida; Furlani, Izadora L.; Oliveira, Juliana M. de; Resende, Diana I. S. P.; Silva, Artur M. S.; Gales, Luís; Pereira,
José A.; et al. Autor correspondente: Sousa, Emília. "Determination of the Absolute Configuration of Bioactive Indole-Containing
Pyrazino[2,1-b]quinazoline-3,6-diones and Study of Their In Vitro Metabolic Profile". Molecules 26 16 (2021): 5070.
http://dx.doi.org/10.3390/molecules26165070.
10.3390/molecules26165070
- Moreira, Joana; Almeida, Joana; Loureiro, Joana B.; Ramos, Helena; Palmeira, Andreia; Pinto, Madalena; Saraiva, Lucília; Cidade,
Honorina. Autor correspondente: Cidade, Honorina. "A Diarylpentanoid with Potential Activation of the p53 Pathway: Combination
of in silico Screening Studies, Synthesis, and Biological Activity Evaluation". ChemMedChem 16 19 (2021): 2969-2981.
http://dx.doi.org/10.1002/cmdc.202100337.
10.1002/cmdc.202100337
- Joana Moreira; Joana Almeida; Lucília Saraiva; Honorina Cidade; Madalena Pinto. "Chalcones as Promising Antitumor Agents by
Targeting the p53 Pathway: An Overview and New Insights in Drug-Likeness". Molecules 26 12 (2021): 3737-3737. https://doi.org/10.3390/molecules26123737.
10.3390/molecules26123737
- Rui Medeiros; Bruno Horta; Joana Freitas-Silva; Jani Silva; Francisca Dias; Emília Sousa; Madalena Pinto; Fátima Cerqueira.
"Effect of 1-Carbaldehyde-3,4-dimethoxyxanthone on Prostate and HPV-18 Positive Cervical Cancer Cell Lines and on Human THP-1
Macrophages". Molecules (2021): https://doi.org/10.3390/molecules26123721.
10.3390/molecules26123721
- Fernando Durães; Andreia Palmeira; Bárbara Cruz; Joana Freitas-Silva; Nikoletta Szemerédi; Luís Gales; Paulo Martins da Costa;
et al. "Antimicrobial Activity of a Library of Thioxanthones and Their Potential as Efflux Pump Inhibitors". Pharmaceuticals
14 6 (2021): 572-572. https://doi.org/10.3390/ph14060572.
10.3390/ph14060572
- Ndongo, Thierno Moussa; Passos, Marieta L. C.; Durães, Fernando; Resende, Diana I. S. P.; Pinto, Madalena; Sousa, Emília;
Saraiva, Maria Lúcia M. F. S.. Autor correspondente: Saraiva, Maria Lúcia M. F. S.. "Microsequential injection analysis/lab-on-valve
system for the automatic evaluation of acetylcholinesterase inhibitors". Archiv der Pharmazie 354 10 (2021): http://dx.doi.org/10.1002/ardp.202100150.
10.1002/ardp.202100150
- Daniel Mendanha; Joana Vieira de Castro; Joana Moreira; Bruno M. Costa; Honorina Cidade; Madalena Pinto; Helena Ferreira;
Nuno M. Neves. "A New Chalcone Derivative with Promising Antiproliferative and Anti-Invasion Activities in Glioblastoma Cells".
Molecules 26 11 (2021): 3383-3383. https://doi.org/10.3390/molecules26113383.
10.3390/molecules26113383
- Fernando Durães; Patrícia M. A. Silva; Pedro Novais; Isabel Amorim; Luís Gales; Cátia I. C. Esteves; Samuel Guieu; et al.
"Tetracyclic Thioxanthene Derivatives: Studies on Fluorescence and Antitumor Activity". Molecules 26 11 (2021): 3315-3315.
https://doi.org/10.3390/molecules26113315.
10.3390/molecules26113315
- Fernando Durães; Diana I. S. P. Resende; Andreia Palmeira; Nikoletta Szemerédi; Madalena M. M. Pinto; Gabriella Spengler;
Emília Sousa. "Xanthones Active against Multidrug Resistance and Virulence Mechanisms of Bacteria". Antibiotics 10
5 (2021): 600-600. https://doi.org/10.3390/antibiotics10050600.
10.3390/antibiotics10050600
- Ana Alves; Paulo Costa; Madalena Pinto; Domingos Ferreira; Marta Correia-da-Silva. "Small Molecules of Marine Origin as Potential
Anti-Glioma Agents". Molecules (2021): https://doi.org/10.3390/molecules26092707.
10.3390/molecules26092707
- Solida Long; Joana B. Loureiro; Carla Carvalho; Luís Gales; Lucília Saraiva; Madalena M. M. Pinto; Ploenthip Puthongking;
Emília Sousa. "Semi-Synthesis of Small Molecules of Aminocarbazoles: Tumor Growth Inhibition and Potential Impact on p53".
Molecules 26 6 (2021): 1637-1637. https://doi.org/10.3390/molecules26061637.
10.3390/molecules26061637
- Madalena M. M. Pinto; Andreia Palmeira; Carla Fernandes; Diana I. S. P. Resende; Emília Sousa; Honorina Cidade; Maria Elizabeth
Tiritan; Marta Correia-da-Silva; Sara Cravo. "From Natural Products to New Synthetic Small Molecules: A Journey through the
World of Xanthones". Molecules 26 2 (2021): 431-431. https://doi.org/10.3390/molecules26020431.
10.3390/molecules26020431
- Almeida, Mariana C.; Resende, Diana I.S.P.; da Costa, Paulo M.; Pinto, Madalena; Sousa, Emília. Autor correspondente: Resende,
Diana I.S.P.. "Tryptophan derived natural marine alkaloids and synthetic derivatives as promising antimicrobial agents". European
Journal of Medicinal Chemistry 209 (2021): 112945. http://dx.doi.org/10.1016/j.ejmech.2020.112945.
10.1016/j.ejmech.2020.112945
- Maia, Miguel; Resende, Diana I.S.P.; Durães, Fernando; Pinto, Madalena; Sousa, Emília. Autor correspondente: Sousa, Emília.
"Xanthenes in Medicinal Chemistry – Synthetic strategies and biological activities". European Journal of Medicinal Chemistry
210 (2021): 113085. http://dx.doi.org/10.1016/j.ejmech.2020.113085.
10.1016/j.ejmech.2020.113085
- Rosa, Gonçalo P.; Palmeira, A.; Resende, Diana I. S. P.; Almeida, Isabel F.; Kane-Pagès, Aida; Barreto, Maria do Carmo; Sousa,
E.; Pinto, Madalena M. M.. "Xanthones for melanogenesis inhibition : Molecular docking and QSAR studies to understand their
anti-tyrosinase activity". (2021): http://hdl.handle.net/10400.3/6053.
10.1016/j.bmc.2020.115873
- Daniela Pereira; Catarina Gonçalves; Beatriz T. Martins; Andreia Palmeira; Vitor Vasconcelos; Madalena Pinto; Joana R. Almeida;
Marta Correia-da-Silva; Honorina Cidade. "Flavonoid Glycosides with a Triazole Moiety for Marine Antifouling Applications:
Synthesis and Biological Activity Evaluation". Marine Drugs (2020): https://doi.org/10.3390/md19010005.
10.3390/md19010005
- Cátia Vilas-Boas; Francisca Carvalhal; Beatriz Pereira; Sílvia Carvalho; Emília Sousa; Madalena M. M. Pinto; Maria José Calhorda;
et al. "One Step Forward towards the Development of Eco-Friendly Antifouling Coatings: Immobilization of a Sulfated Marine-Inspired
Compound". Marine Drugs 18 10 (2020): 489-489. https://doi.org/10.3390/md18100489.
10.3390/md18100489
- Mariana Pereira Silva; Lucília Saraiva; Madalena Pinto; Maria Emília Sousa. "Boronic Acids and Their Derivatives in Medicinal
Chemistry: Synthesis and Biological Applications". Molecules (2020): https://doi.org/10.3390/molecules25184323.
10.3390/molecules25184323
- Márcia Martins; Renata Silva; Madalena M. M. Pinto; Emília Sousa. "Marine Natural Products, Multitarget Therapy and Repurposed
Agents in Alzheimer’s Disease". Pharmaceuticals 13 9 (2020): 242-242. https://doi.org/10.3390/ph13090242.
10.3390/ph13090242
- Joana R. Almeida; Andreia Palmeira; Alexandre Campos; Isabel Cunha; Micaela Freitas; Aldo Barreiro Felpeto; Maria V. Turkina;
et al. "Structure-Antifouling Activity Relationship and Molecular Targets of Bio-Inspired(thio)xanthones". Biomolecules
(2020): https://doi.org/10.3390/biom10081126.
10.3390/biom10081126
- Pinto, Madalena. "Targeting antimicrobial drug resistance with marine natural products". International Journal of Antimicrobial
Agents (2020): http://dx.doi.org/10.1016/j.ijantimicag.2020.106005.
10.1016/j.ijantimicag.2020.106005
- Pinto, Madalena. "Preliminary Virtual Screening Studies to Identify GRP78 Inhibitors Which May Interfere with SARS-CoV-2 Infection".
Pharmaceuticals (2020): http://dx.doi.org/10.3390/ph13060132.
10.3390/ph13060132
- Diana I. S. P. Resende; Mariana C. Almeida; Bruna Maciel; Carmo H; José Sousa Lobo; Carlotta Dal Pozzo; Sara M. Cravo; et
al. "Efficacy, Stability, and Safety Evaluation of New Polyphenolic Xanthones Towards Identification of Bioactive Compounds
to Fight Skin Photoaging". Molecules (2020): https://www.mdpi.com/1420-3049/25/12/2782.
10.3390/molecules25122782
- Ana Alves; Emília Sousa; Anake Kijjoa; Madalena Pinto. "Marine-Derived Compounds with Potential Use as Cosmeceuticals and
Nutricosmetics". Molecules (2020): https://doi.org/10.3390/molecules25112536.
10.3390/molecules25112536
- Pinto, Madalena. "Synthesis of a Small Library of Nature-Inspired Xanthones and Study of Their Antimicrobial Activity". Molecules
(2020): http://dx.doi.org/10.3390/molecules25102405.
10.3390/molecules25102405
- Madalena M.M. Pinto; Carla Fernandes; Maria E. Tiritan. "Chiral Separations in Preparative Scale: A Medicinal Chemistry Point
of View". Molecules 25 8 (2020): 1931-1931. https://doi.org/10.3390/molecules25081931.
10.3390/molecules25081931
- Maria Elizabeth Tiritan; Madalena Pinto; Carla Fernandes. "Enantioselective Synthesis, Enantiomeric Separations and Chiral
Recognition". Molecules 25 7 (2020): 1713-1713. https://doi.org/10.3390/molecules25071713.
10.3390/molecules25071713
- Moreira, Joana; Saraiva, Lucilia; Pinto, Madalena; Cidade, Honorina. "Diarylpentanoids with antitumor activity: A critical
review of structure-activity relationship studies". European Journal of Medicinal Chemistry 192 (2020): 112177. http://dx.doi.org/10.1016/j.ejmech.2020.112177.
Publicado • 10.1016/j.ejmech.2020.112177
- Pedro Brandão; Joana Moreira; Joana Almeida; Nair Nazareth; Ivo E. Sampaio-Dias; Vitor Vasconcelos; Rosário Martins; et al.
"Norhierridin B, a New Hierridin B-Based Hydroquinone with Improved Antiproliferative Activity". Molecules 25 7 (2020):
1578-1578. https://doi.org/10.3390/molecules25071578.
10.3390/molecules25071578
- Loureiro, Daniela R. P.; Magalhães, Álvaro F.; Soares, José X.; Pinto, Joana; Azevedo, Carlos M. G.; Vieira, Sara; Henriques,
Ana; et al. "Yicathins B and C and analogues: total synthesis, lipophilicity and biological activities". ChemMedChem
(2020): http://dx.doi.org/10.1002/cmdc.201900735.
Publicado • 10.1002/cmdc.201900735
- Neves, Ana R.; Almeida, Joana R.; Carvalhal, Francisca; Câmara, Amadeu; Pereira, Sandra; Antunes, Jorge; Vasconcelos, Vitor;
et al. "Overcoming environmental problems of biocides: Synthetic bile acid derivatives as a sustainable alternative". Ecotoxicology
and Environmental Safety 187 (2020): 109812. http://dx.doi.org/10.1016/j.ecoenv.2019.109812.
Publicado • 10.1016/j.ecoenv.2019.109812
- Cidade, Honorina; Rocha, Verónica; Palmeira, Andreia; Marques, Cláudia; Tiritan, Maria Elizabeth; Ferreira, Helena; Lobo,
José Sousa; et al. "In silico and in vitro antioxidant and cytotoxicity evaluation of oxygenated xanthone derivatives". Arabian
Journal of Chemistry 13 1 (2020): 17-26. http://dx.doi.org/10.1016/j.arabjc.2017.01.006.
Publicado • 10.1016/j.arabjc.2017.01.006
- Diana I. S. P. Resende; Fernando Durães; Miguel Maia; Emília Sousa; Madalena M. M. Pinto. "Recent advances in the synthesis
of xanthones and azaxanthones". Organic Chemistry Frontiers (2020): https://doi.org/10.1039/D0QO00659A.
10.1039/D0QO00659A
- Long, Solida; Resende, Diana I. S. P.; Palmeira, Andreia; Kijjoa, Anake; Silva, Artur M. S.; Tiritan, Maria Elizabeth; Pereira-Terra,
Patrícia; et al. "New marine-derived indolymethyl pyrazinoquinazoline alkaloids with promising antimicrobial profiles". RSC
Advances 10 52 (2020): 31187-31204. http://dx.doi.org/10.1039/d0ra05319h.
10.1039/d0ra05319h
- Pinto, Patricia#; Machado, Carmen Mariana#; Moreira, Joana#; Almeida, José Diogo P.; Silva, Patrícia M.A.; Henriques, Ana
C.; Soares, José X.; et al. "Chalcone derivatives targeting mitosis: synthesis, evaluation of antitumor activity and lipophilicity".
European Journal of Medicinal Chemistry 184 (2019): 111752. http://dx.doi.org/10.1016/j.ejmech.2019.111752.
Publicado • 10.1016/j.ejmech.2019.111752
- Pereira, Daniela; Lima, Raquel T.; Palmeira, Andreia; Seca, Hugo; Soares, Joana; Gomes, Sara; Raimundo, Liliana; et al. "Design
and synthesis of new inhibitors of p53–MDM2 interaction with a chalcone scaffold". Arabian Journal of Chemistry 12
8 (2019): 4150-4161. http://dx.doi.org/10.1016/j.arabjc.2016.04.015.
10.1016/j.arabjc.2016.04.015
- Phyo, Ye' Zaw; Teixeira, Joana; Tiritan, Maria Elizabeth; Cravo, Sara; Palmeira, Andreia; Gales, Luís; Silva, Artur M.S.;
et al. "New chiral stationary phases for liquid chromatography based on small molecules: Development, enantioresolution evaluation
and chiral recognition mechanisms". Chirality 32 1 (2019): 81-97. http://dx.doi.org/10.1002/chir.23142.
Publicado • 10.1002/chir.23142
- Maribel Teixeira; Madalena Pedro; Maria São José Nascimento; Madalena M. M. Pinto; Carlos Maurício Barbosa. "Development and
characterization of PLGA nanoparticles containing 1,3-dihydroxy-2-methylxanthone with improved antitumor activity on a human
breast cancer cell line". Pharmaceutical Development and Technology (2019): 1-11. https://doi.org/10.1080/10837450.2019.1638398.
10.1080/10837450.2019.1638398
- Silva, S.; Ferreira, M.; Oliveira, A.S.; Magalhães, C.; Sousa, M.E.; Pinto, M.; Sousa Lobo, J.M.; Almeida, I.F.. "Evolution
of the use of antioxidants in anti-ageing cosmetics". International Journal of Cosmetic Science 41 4 (2019): 378-386.
http://dx.doi.org/10.1111/ics.12551.
Publicado • 10.1111/ics.12551
- do Carmo, João P; Phyo, Ye Zaw; Palmeira, Andreia; Tiritan, Maria Elizabeth; Afonso, Carlos; Kijjoa, Anake; M Pinto, Madalena
M; Fernandes, Carla. "Enantioseparation, recognition mechanisms and binding of xanthones on human serum albumin by liquid
chromatography". Bioanalysis 11 13 (2019): 1255-1274. http://dx.doi.org/10.4155/bio-2019-0074.
Publicado • 10.4155/bio-2019-0074
- Ana J. S. Alves; José A. Pereira; Tida Dethoup; Sara Cravo; Sharad Mistry; Artur M. S. Silva; Madalena M. M. Pinto; Anake
Kijjoa. "A New Meroterpene, A New Benzofuran Derivative and Other Constituents from Cultures of the Marine Sponge-Associated
Fungus Acremonium persicinum KUFA 1007 and Their Anticholinesterase Activities". Marine Drugs 17 6 (2019): 379-379.
https://doi.org/10.3390/md17060379.
10.3390/md17060379
- Viviana Silva; Fátima Cerqueira; Nair Nazareth; Rui Medeiros; Amélia Sarmento; Emília Sousa; Madalena Pinto. "1,2-Dihydroxyxanthone:
Effect on A375-C5 Melanoma Cell Growth Associated with Interference with THP-1 Human Macrophage Activity". Pharmaceuticals
12 2 (2019): 85-85. https://doi.org/10.3390/ph12020085.
10.3390/ph12020085
- Agostinho Lemos; Ana Sara Gomes; Joana B. Loureiro; Pedro Brandão; Andreia Palmeira; Madalena M. M. Pinto; Lucília Saraiva;
Maria Emília Sousa. "Synthesis, Biological Evaluation, and In Silico Studies of Novel Aminated Xanthones as Potential p53-Activating
Agents". Molecules 24 10 (2019): 1975-1975. https://doi.org/10.3390/molecules24101975.
10.3390/molecules24101975
- Gomes, Sara; Raimundo, Liliana; Soares, Joana; Loureiro, Joana B.; Leão, Mariana; Ramos, Helena; Monteiro, Madalena N.; et
al. "New inhibitor of the TAp73 interaction with MDM2 and mutant p53 with promising antitumor activity against neuroblastoma".
Cancer Letters 446 (2019): 90-102. http://dx.doi.org/10.1016/j.canlet.2019.01.014.
Publicado • 10.1016/j.canlet.2019.01.014
- Francisca Carvalhal; Ricardo R. Cristelo; Diana Resende; Madalena M. M. Pinto; E Sousa; Marta Correia-da-Silva. "Antithrombotics
from the Sea: Polysaccharides and Beyond". Marine Drugs (2019): https://www.mdpi.com/1660-3397/17/3/170.
10.3390/md17030170
- Carla Fernandes; Maria Carraro; João Ribeiro; Joana Araújo; Maria Tiritan; Madalena Pinto. "Synthetic Chiral Derivatives of
Xanthones: Biological Activities and Enantioselectivity Studies". Molecules 24 4 (2019): 791-791. https://doi.org/10.3390/molecules24040791.
10.3390/molecules24040791
- Joana Teixeira; Maria Elizabeth Tiritan; Madalena M. M. Pinto; Carla Fernandes. "Chiral Stationary Phases for Liquid Chromatography:
Recent Developments". Molecules (2019): https://www.mdpi.com/1420-3049/24/5/865.
10.3390/molecules24050865
- Solida Long; Diana Resende; Anake Kijjoa; Artur M. S. Silva; Ricardo Fernandes; Xavier CP; M. Helena Vasconcelos; E Sousa;
Madalena M. M. Pinto. "Synthesis of New Proteomimetic Quinazolinone Alkaloids and Evaluation of Their Neuroprotective and
Antitumor Effects". Molecules (2019): http://www.mdpi.com/1420-3049/24/3/534.
10.3390/molecules24030534
- Decha Kumla; Tida Dethoup; Luis Gales; José A Pereira; Joana Freitas-Silva; Paulo Martins da Costa; Artur M. S. Silva; Madalena
M. M. Pinto; Anake Kijjoa. "Erubescensoic Acid, a New Polyketide and a Xanthonopyrone SPF-3059-26 from the Culture of the
Marine Sponge-Associated Fungus Penicillium erubescens KUFA 0220 and Antibacterial Activity Evaluation of Some of Its
Constituents". Molecules (2019): http://www.mdpi.com/1420-3049/24/1/208.
10.3390/molecules24010208
- Daniela R. P. Loureiro; José Soares; Joana C. Costa; Álvaro F. Magalhães; Carlos M. G. Azevedo; Madalena M. M. Pinto; Carlos
Afonso. "Structures, Activities and Drug-Likeness of Anti-Infective Xanthone Derivatives Isolated from the Marine Environment:
A Review". Molecules (2019): http://www.mdpi.com/1420-3049/24/2/243.
10.3390/molecules24020243
- Joana Araújo; Carla Fernandes; Madalena M. M. Pinto; Maria Elizabeth Tiritan. "Chiral Derivatives of Xanthones with Antimicrobial
Activity". Molecules (2019): http://www.mdpi.com/1420-3049/24/2/314.
10.3390/molecules24020314
- Ana Alves; Marta Correia-da-Silva; Claúdia Nunes; E Sousa; Patrícia M. A. Silva; Hassan Bousbaa; Francisca Rodrigues; et al.
"Discovery of a New Xanthone against Glioma: Synthesis and Development of (Pro)liposome Formulations". Molecules (2019):
http://www.mdpi.com/1420-3049/24/3/409.
10.3390/molecules24030409
- Ana Jesus; Marta Correia-da-Silva; Carlos Afonso; Madalena M. M. Pinto; Honorina Cidade. "Isolation and Potential Biological
Applications of Haloaryl Secondary Metabolites from Macroalgae". Marine Drugs (2019): http://www.mdpi.com/1660-3397/17/2/73.
10.3390/md17020073
- João Ribeiro; Cláudia Veloso; Carla Fernandes; Maria Elizabeth Tiritan; Madalena M. M. Pinto. "Carboxyxanthones: Bioactive
Agents and Molecular Scaffold for Synthesis of Analogues and Derivatives". Molecules (2019): http://www.mdpi.com/1420-3049/24/1/180.
10.3390/molecules24010180
- Diana I. S. P. Resende; Papichaya Boonpothong; Emília Sousa; Anake Kijjoa; Madalena M. M. Pinto. "Chemistry of the fumiquinazolines
and structurally related alkaloids". Natural Product Reports (2019): https://doi.org/10.1039/C8NP00043C.
10.1039/C8NP00043C
- Raquel T. Lima; Diana Sousa; Ana Sara Gomes; Nuno Mendes; Rune Matthiesen; Madalena Pedro; Franklim Marques; et al. "The Antitumor
Activity of a Lead Thioxanthone is Associated with Alterations in Cholesterol Localization". Molecules (2018): http://www.mdpi.com/1420-3049/23/12/3301.
10.3390/molecules23123301
- Joana Moreira; Diana Ribeiro; Patrícia Silva; Nair Nazareth; Madalena N Monteiro; Andreia Palmeira; Lucília Saraiva; et al.
"New Alkoxy Flavone Derivatives Targeting Caspases: Synthesis and Antitumor Activity Evaluation". Molecules (2018):
http://www.mdpi.com/1420-3049/24/1/129.
10.3390/molecules24010129
- Diana Resende; Patrícia Pereira-Terra; Ângela S. Inácio; Paulo Martins da Costa; Eugénia Pinto; E Sousa; Madalena M. M.
Pinto. "Lichen Xanthones as Models for New Antifungal Agents". Molecules (2018): http://www.mdpi.com/1420-3049/23/10/2617.
10.3390/molecules23102617
- Pinto, Madalena. "Antitumor Activity of Quinazolinone Alkaloids Inspired by Marine Natural Products". Marine Drugs
(2018): http://www.mdpi.com/1660-3397/16/8/261.
10.3390/md16080261
- Ana Neves; Marta Correia-da-Silva; Patrícia Silva; Diana Ribeiro; Emília Sousa; Hassan Bousbaa; Madalena Pinto. "Synthesis
of New Glycosylated Flavonoids with Inhibitory Activity on Cell Growth". Molecules (2018): https://doi.org/10.3390/molecules23051093.
10.3390/molecules23051093
- Martins, Beatriz T.; Correia da Silva, Marta; Pinto, Madalena; Cidade, Honorina; Kijjoa, Anake. "Marine natural flavonoids:
chemistry and biological activities". Natural Product Research 33 22 (2018): 3260-3272. http://dx.doi.org/10.1080/14786419.2018.1470514.
Publicado • 10.1080/14786419.2018.1470514
- Pinto, Madalena. "Old Drugs as New Treatments for Neurodegenerative Diseases". Pharmaceuticals (2018): http://www.mdpi.com/1424-8247/11/2/44.
10.3390/ph11020044
- Pinto, Madalena. "Bis-Indolyl Benzenoids, Hydroxypyrrolidine Derivatives and Other Constituents from Cultures of
the Marine Sponge-Associated Fungus Aspergillus candidus KUFA0062". Marine Drugs (2018): http://www.mdpi.com/1660-3397/16/4/119.
10.3390/md16040119
- Pinto, Madalena. "Chiral Thioxanthones as Modulators of P-glycoprotein: Synthesis and Enantioselectivity Studies". Molecules
(2018): http://www.mdpi.com/1420-3049/23/3/626.
10.3390/molecules23030626
- Pinto, Madalena. "Marine Natural Peptides: Determination of Absolute Configuration Using Liquid Chromatography Methods and
Evaluation of Bioactivities". Molecules (2018): http://www.mdpi.com/1420-3049/23/2/306.
10.3390/molecules23020306
- Pinto, Madalena. "Enantiomeric Resolution and Docking Studies of Chiral Xanthonic Derivatives on Chirobiotic Columns". Molecules
(2018): http://www.mdpi.com/1420-3049/23/1/142.
10.3390/molecules23010142
- Pinto, Madalena. "A New Dihydrochromone Dimer and Other Secondary Metabolites from Cultures of the Marine Sponge-Associated
Fungi Neosartorya fennelliae KUFA 0811 and Neosartorya tsunodae KUFC 9213". Marine Drugs (2017):
http://www.mdpi.com/1660-3397/15/12/375.
10.3390/md15120375
- Pinto, Madalena. "Chiral Stationary Phases for Liquid Chromatography Based on Chitin- and Chitosan-Derived Marine Polysaccharides".
Symmetry (2017): http://www.mdpi.com/2073-8994/9/9/190.
10.3390/sym9090190
- Pinto, Madalena. "Chiral Separation in Preparative Scale: A Brief Overview of Membranes as Tools for Enantiomeric Separation".
Symmetry (2017): http://www.mdpi.com/2073-8994/9/10/206.
10.3390/sym9100206
- Pinto, Madalena. "Chiral Derivatives of Xanthones: Investigation of the Effect of Enantioselectivity on Inhibition of Cyclooxygenases
(COX-1 and COX-2) and Binding Interaction with Human Serum Albumin". Pharmaceuticals (2017): http://www.mdpi.com/1424-8247/10/2/50.
10.3390/ph10020050
- Pinto, Madalena. "Antibacterial and antibiofilm activities of the metabolites isolated from the culture of the mangrove-derived
endophytic fungus Eurotium chevalieri KUFA0006". Phytochemistry (2017):
10.1016/j.phytochem.2017.05.015
- Reis-Mendes, A.; Gomes, A.S.; Carvalho, R.A.; Carvalho, F.; Remião, F.; Pinto, M.; Bastos, M.L.; Sousa, E.; Costa, V.M.. "Naphthoquinoxaline
metabolite of mitoxantrone is less cardiotoxic than the parent compound and it can be a more cardiosafe drug in anticancer
therapy". Archives of Toxicology 91 4 (2017): 1871-1890. http://www.scopus.com/inward/record.url?eid=2-s2.0-84987667526&partnerID=MN8TOARS.
10.1007/s00204-016-1839-z
- Pinto, Madalena. "Anticancer and cancer preventive compounds from edible marine organisms". Seminars in Cancer Biology
(2017):
10.1016/j.semcancer.2017.03.011
- Pinto, Madalena. "Quantification of 1-(propan-2-ylamino)-4-propoxy-9h-thioxanthen-9-one (tx5), a newly synthetized p-glycoprotein
inducer/activator, in biological samples: method development and validation". Biomedical Chromatography (2017):
10.1002/bmc.3802
- Inês Cruz; Ploenthip Puthongking; Sara Cravo; Andreia Palmeira; Honorina Cidade; Madalena Pinto; Emília Sousa. "Xanthone and
Flavone Derivatives as Dual Agents with Acetylcholinesterase Inhibition and Antioxidant Activity as Potential Anti-Alzheimer
Agents". Journal of Chemistry 2017 (2017): 1-16. https://doi.org/10.1155%2F2017%2F8587260.
10.1155/2017/8587260
- Pinto, Madalena. "The importance of drug metabolites synthesis: the case-study of cardiotoxic anticancer drugs". Drug Metabolism
Reviews (2017):
10.1080/03602532.2017.1316285
- Pinto, Madalena. "Antifouling potential of Nature-inspired sulfated compounds". Scientific Reports (2017):
10.1038/srep42424
- Pinto, Madalena. "Resolution, determination of enantiomeric purity and chiral recognition mechanism of new xanthone derivatives
on (S,S)-whelk-O1 stationary phase". Chirality (2017):
10.1002/chir.22703
- Pinto, Madalena. "Chiral stationary phases based on small molecules: an update of the last seventeen years". Separation
Purification Reviews (2017):
10.1080/15422119.2017.1326939
- Pinto, Madalena. "New chiral stationary phases based on xanthone derivatives for liquid chromatography". Chirality
(2017):
10.1002/chir.22706
- Pinto, Madalena. "A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug
resistance cells". Bioorganic & Medicinal Chemistry (2017):
10.1016/j.bmc.2016.11.023
- Barbosa, J.; Lima, R.T.; Sousa, D.; Gomes, A.S.; Palmeira, A.; Seca, H.; Choosang, K.; et al. "Screening a small library of
xanthones for antitumor activity and identification of a hit compound which induces apoptosis". Molecules 21 1 (2016):
http://www.scopus.com/inward/record.url?eid=2-s2.0-85000443221&partnerID=MN8TOARS.
10.3390/molecules21010081
- Long, S.; Sousa, E.; Kijjoa, A.; Pinto, M.M.M.. "Marine natural products as models to circumvent multidrug resistance". Molecules
21 7 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84979211012&partnerID=MN8TOARS.
10.3390/molecules21070892
- Zin, W.W.M.; Buttachon, S.; Dethoup, T.; Fernandes, C.; Cravo, S.; Pinto, M.M.M.; Gales, L.; et al. "New cyclotetrapeptides
and a new diketopiperzine derivative from the marine sponge-associated fungus Neosartorya glabra KUFA 0702". Marine Drugs
14 7 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84979518314&partnerID=MN8TOARS.
10.3390/md14070136
- De Almeida, A.P.; Quintela, J.C.; Chaves, D.S.A.; Barbosa, J.F.; Pinto, M.; Pedroa, M.. "The cytotoxic effect of extracts
obtained from Cecropia catharinensis cuatrec (Urticaceae)". Revista Virtual de Quimica 8 1 (2016): 27-34. http://www.scopus.com/inward/record.url?eid=2-s2.0-84966351791&partnerID=MN8TOARS.
10.5935/1984-6835.20160002
- Prompanya, C.; Dethoup, T.; Gales, L.; Lee, M.; Pereira, J.A.C.; Silva, A.M.S.; Pinto, M.M.M.; Kijjoa, A.. "New polyketides
and new benzoic acid derivatives from the marine sponge-associated fungus Neosartorya quadricincta KUFA 0081". Marine Drugs
14 7 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84979223422&partnerID=MN8TOARS.
10.3390/md14070134
- Lima, R.T.; Sousa, D.; Paiva, A.M.; Palmeira, A.; Barbosa, J.; Pedro, M.; Pinto, M.M.; Sousa, E.; Vasconcelos, M.H.. "Modulation
of autophagy by a thioxanthone decreases the viability of melanoma cells". Molecules 21 10 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84992754198&partnerID=MN8TOARS.
10.3390/molecules21101343
- Lemos, A.; Leão, M.; Soares, J.; Palmeira, A.; Pinto, M.; Saraiva, L.; Sousa, M.E.. "Medicinal Chemistry Strategies to Disrupt
the p53-MDM2/MDMX Interaction". Medicinal Research Reviews (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84977595497&partnerID=MN8TOARS.
10.1002/med.21393
- Fonseca, J.; Marques, S.; Silva, P.M.A.; Brandão, P.; Cidade, H.; Pinto, M.M.; Bousbaa, H.. "Prenylated chalcone 2 acts as
an antimitotic agent and enhances the chemosensitivity of tumor cells to paclitaxel". Molecules 21 8 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84980407559&partnerID=MN8TOARS.
10.3390/molecules21080982
- Gomes, A.S.; Brandão, P.; Fernandes, C.S.G.; Da Silva, M.R.P.C.; De Sousa, M.E.D.S.P.; De Magalhães Pinto, M.M.. "Drug-like
properties and ADME of xanthone derivatives: The antechamber of clinical trials". Current Medicinal Chemistry 23 32
(2016): 3654-3686. http://www.scopus.com/inward/record.url?eid=2-s2.0-84995948323&partnerID=MN8TOARS.
10.2174/0929867323666160425113058
- Neves, A.R.; Correia-Da-Silva, M.; Sousa, E.; Pinto, M.. "Structure-activity relationship studies for multitarget antithrombotic
drugs". Future Medicinal Chemistry 8 18 (2016): 2305-2355. http://www.scopus.com/inward/record.url?eid=2-s2.0-84999143299&partnerID=MN8TOARS.
10.4155/fmc-2015-0020
- Silva, B.; Fernandes, C.; Tiritan, M.E.; Pinto, M.M.M.; Valente, M.J.; Carvalho, M.; de Pinho, P.G.; Remião, F.. "Chiral enantioresolution
of cathinone derivatives present in “legal highs”, and enantioselectivity evaluation on cytotoxicity of 3,4-methylenedioxypyrovalerone
(MDPV)". Forensic Toxicology 34 2 (2016): 372-385. http://www.scopus.com/inward/record.url?eid=2-s2.0-84974807559&partnerID=MN8TOARS.
10.1007/s11419-016-0324-y
- Pinto, Madalena. "Strategies to Overcome Heparins’ Low Oral Bioavailability". Pharmaceuticals (2016):
10.3390/ph9030037
- Silva, R.; Palmeira, A.; Carmo, H.; Barbosa, D.J.; Gameiro, M.; Gomes, A.; Paiva, A.M.; et al. "P-glycoprotein induction in
Caco-2 cells by newly synthetized thioxanthones prevents paraquat cytotoxicity". Archives of Toxicology 89 10 (2015):
1783-1800. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942198190&partnerID=MN8TOARS.
10.1007/s00204-014-1333-4
- Leão, M.; Soares, J.; Gomes, S.; Raimundo, L.; Ramos, H.; Bessa, C.; Queiroz, G.; et al. "Enhanced cytotoxicity of prenylated
chalcone against tumour cells via disruption of the p53-MDM2 interaction". Life Sciences 142 (2015): 60-65. http://www.scopus.com/inward/record.url?eid=2-s2.0-84944769312&partnerID=MN8TOARS.
10.1016/j.lfs.2015.10.015
- Bessa, L.J.; Palmeira, A.; Gomes, A.S.; Vasconcelos, V.; Sousa, E.; Pinto, M.; Da Costa, P.M.. "Synergistic effects between
thioxanthones and oxacillin against methicillin-resistant staphylococcus aureus". Microbial Drug Resistance 21 4 (2015):
404-415. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937772878&partnerID=MN8TOARS.
10.1089/mdr.2014.0162
- Mbefo, M.K.; Fares, M.-B.; Paleologou, K.; Oueslati, A.; Yin, G.; Tenreiro, S.; Pinto, M.; et al. "Parkinson disease mutant
E46K enhances a-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo". Journal of Biological Chemistry
290 15 (2015): 9412-9427. http://www.scopus.com/inward/record.url?eid=2-s2.0-84927144360&partnerID=MN8TOARS.
10.1074/jbc.M114.610774
- Oliveira, A.S.; Sousa, E.; Vasconcelos, M.H.; Pinto, M.. "Curcumin: A natural lead for potential new drug candidates". Current
Medicinal Chemistry 22 36 (2015): 4196-4232. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960971101&partnerID=MN8TOARS.
- Pinto, Madalena. "Thioxanthones derivatives as dual inhibitors of P-glycoprotein and tumor cell growth". Toxicology Letters
(2015):
doi:10.1016/j.toxlet.2015.08.137
- Pinto, Madalena. "Molecular clefts of Rebek revisited: potential application as drug carriers for the antiviral acyclovir".
J Incl Phenom Macrocycl Chem (2015):
10.1007/s10847-015-0554-3
- Pinto, Madalena. "Derivados xantónicos quirais: aplicações em Química Medicinal e uma nova abordagem em Cromatografia Líquida".
Scientia Chromatographica (2015):
10.4322/sc.2015.000
- Prompanya, C.; Fernandes, C.; Cravo, S.; Pinto, M.M.M.; Dethoup, T.; Silva, A.M.S.; Kijjoa, A.. "A new cyclic hexapeptide
and a new isocoumarin derivative from the marine sponge-associated fungus Aspergillus similanensis KUFA 0013". Marine Drugs
13 3 (2015): 1432-1450. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925846750&partnerID=MN8TOARS.
10.3390/md13031432
- Zin, W.W.M.; Buttachon, S.; Buaruang, J.; Gales, L.; Pereira, J.A.; Pinto, M.M.M.; Silva, A.M.S.; Kijjoa, A.. "A new meroditerpene
and a new tryptoquivaline analog from the algicolous fungus Neosartorya takakii KUFC 7898". Marine Drugs 13 6 (2015):
3776-3790. http://www.scopus.com/inward/record.url?eid=2-s2.0-84936791340&partnerID=MN8TOARS.
10.3390/md13063776
- Pedro Gonçalves, A.; Silva, N.; Oliveira, C.; Kowbel, D.J.; Glass, N.L.; Kijjoa, A.; Palmeira, A.; et al. "Transcription profiling
of the Neurospora crassa response to a group of synthetic (thio)xanthones and a natural acetophenone". Genomics Data
4 (2015): 26-32. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929428256&partnerID=MN8TOARS.
10.1016/j.gdata.2015.02.001
- Vale, A.P.; Cidade, H.; Pinto, M.; Oliveira, M.B.P.P.. "Effect of sprouting and light cycle on antioxidant activity of Brassica
oleracea varieties". Food Chemistry 165 (2014): 379-387. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902682564&partnerID=MN8TOARS.
10.1016/j.foodchem.2014.05.122
- Correia-da-Silva, M.; Sousa, E.; Pinto, M.M.M.. "Emerging Sulfated Flavonoids and other Polyphenols as Drugs: Nature as an
Inspiration". Medicinal Research Reviews 34 2 (2014): 223-279. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893358163&partnerID=MN8TOARS.
10.1002/med.21282
- Masawang, K.; Pedro, M.; Cidade, H.; Reis, R.M.; Neves, M.P.; Corrêa, A.G.; Sudprasert, W.; Bousbaa, H.; Pinto, M.M.. "Evaluation
of 2',4'-dihydroxy-3,4,5-trimethoxychalcone as antimitotic agent that induces mitotic catastrophe in MCF-7 breast cancer cells".
Toxicology Letters 229 2 (2014): 393-401. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904342840&partnerID=MN8TOARS.
10.1016/j.toxlet.2014.06.016
- Silva, R.; Sousa, E.; Carmo, H.; Palmeira, A.; Barbosa, D.J.; Gameiro, M.; Pinto, M.; De Lourdes Bastos, M.; Remião, F.. "Induction
and activation of P-glycoprotein by dihydroxylated xanthones protect against the cytotoxicity of the P-glycoprotein substrate
paraquat". Archives of Toxicology 88 4 (2014): 937-951. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897110064&partnerID=MN8TOARS.
10.1007/s00204-014-1193-y
- Fernandes, C.; Masawang, K.; Tiritan, M.E.; Sousa, E.; De Lima, V.; Afonso, C.; Bousbaa, H.; et al. "New chiral derivatives
of xanthones: Synthesis and investigation of enantioselectivity as inhibitors of growth of human tumor cell lines". Bioorganic
and Medicinal Chemistry 22 3 (2014): 1049-1062. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892824290&partnerID=MN8TOARS.
10.1016/j.bmc.2013.12.042
- Prompanya, C.; Dethoup, T.; Bessa, L.J.; Pinto, M.M.M.; Gales, L.; Costa, P.M.; Silva, A.M.S.; Kijjoa, A.. "New isocoumarin
derivatives and meroterpenoids from the marine sponge-associated fungus Aspergillus similanensis sp. Nov. KUFA 0013". Marine
Drugs 12 10 (2014): 5160-5173. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925843185&partnerID=MN8TOARS.
10.3390/md12105160
- Pereira, C.; Lopes-Rodrigues, V.; Coutinho, I.; Neves, M.P.; Lima, R.T.; Pinto, M.; Cidade, H.; Vasconcelos, M.H.; Saraiva,
L.. "Potential small-molecule activators of caspase-7 identified using yeast-based caspase-3 and -7 screening assays". European
Journal of Pharmaceutical Sciences 54 1 (2014): 8-16. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893050056&partnerID=MN8TOARS.
10.1016/j.ejps.2013.12.017
- Costa, E.V.; Sousa, E.; Choosang, K.; Singh, S.; Rocha, J.; Lima, R.T.; Pakkong, P.; et al. "Structure based design, synthesis,
and evaluation of potential inhibitors of steroid sulfatase". Current Topics in Medicinal Chemistry 14 8 (2014): 1033-1044.
http://www.scopus.com/inward/record.url?eid=2-s2.0-84903714075&partnerID=MN8TOARS.
10.2174/1568026614666140324124807
- Paiva, A.M.; Pinto, M.M.; Sousa, E.. "A century of thioxanthones: Through synthesis and biological applications". Current
Medicinal Chemistry 20 19 (2013): 2438-2457. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878000587&partnerID=MN8TOARS.
10.2174/0929867311320190004
- Sousa, E.; Palmeira, A.; Cordeiro, A.S.; Sarmento, B.; Ferreira, D.; Lima, R.T.; Helena Vasconcelos, M.; Pinto, M.. "Bioactive
xanthones with effect on P-glycoprotein and prediction of intestinal absorption". Medicinal Chemistry Research 22 5
(2013): 2115-2123. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879681792&partnerID=MN8TOARS.
10.1007/s00044-012-0203-y
- Paiva, A.M.; Teixeira, M.; Pereira, R.; Barbosa, C.M.; Sousa, E.; Pinto, M.M.M.. "Development and validation of an HPLC method
for the quantification of a cytotoxic dihydropyranoxanthone in biodegradable nanoparticles". International Journal of Drug
Delivery 5 2 (2013): 224-232. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904121584&partnerID=MN8TOARS.
- Paiva, A.M.; Pinto, R.A.; Teixeira, M.; Barbosa, C.M.; Lima, R.T.; Vasconcelos, M.H.; Sousa, E.; Pinto, M.. "Development of
noncytotoxic PLGA nanoparticles to improve the effect of a new inhibitor of p53-MDM2 interaction". International Journal
of Pharmaceutics 454 1 (2013): 394-402. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884149481&partnerID=MN8TOARS.
10.1016/j.ijpharm.2013.07.017
- Leão, M.; Pereira, C.; Bisio, A.; Ciribilli, Y.; Paiva, A.M.; Machado, N.; Palmeira, A.; et al. "Discovery of a new small-molecule
inhibitor of p53-MDM2 interaction using a yeast-based approach". Biochemical Pharmacology 85 9 (2013): 1234-1245. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875712215&partnerID=MN8TOARS.
10.1016/j.bcp.2013.01.032
- Fernandes, C.; Palmeira, A.; Santos, A.; Tiritan, M.E.; Afonso, C.; Pinto, M.M.. "Enantioresolution of chiral derivatives
of xanthones on (S,S)-Whelk-O1 and l -phenylglycine stationary phases and chiral recognition mechanism by docking approach
for (S,S)-Whelk-O1". Chirality 25 2 (2013): 89-100. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872834041&partnerID=MN8TOARS.
10.1002/chir.22112
- Azevedo, C.M.G.; Afonso, C.M.M.; Sousa, D.; Lima, R.T.; Helena Vasconcelos, M.; Pedro, M.; Barbosa, J.; et al. "Multidimensional
optimization of promising antitumor xanthone derivatives". Bioorganic and Medicinal Chemistry 21 11 (2013): 2941-2959.
http://www.scopus.com/inward/record.url?eid=2-s2.0-84877815889&partnerID=MN8TOARS.
10.1016/j.bmc.2013.03.079
- Cazal, C.M.; Choosang, K.; Severino, V.G.P.; Fernandes, J.B.; da Silva, M.F.G.F.; Vieira, P.C.; Nascimento, M.S.J.; et al.
"Natural compounds with cell growth inhibitory activity in human tumor cell lines". Anti-Cancer Agents in Medicinal Chemistry
13 10 (2013): 1582-1589. http://www.scopus.com/inward/record.url?eid=2-s2.0-84898928442&partnerID=MN8TOARS.
10.2174/1871520613666131125122857
- Azevedo, C.M.G.; Afonso, C.M.M.; Soares, J.X.; Reis, S.; Sousa, D.; Lima, R.T.; Vasconcelos, M.H.; et al. "Pyranoxanthones:
Synthesis, growth inhibitory activity on human tumor cell lines and determination of their lipophilicity in two membrane models".
European Journal of Medicinal Chemistry 69 (2013): 798-816. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885009924&partnerID=MN8TOARS.
10.1016/j.ejmech.2013.09.012
- Fernandes, C.; Tiritan, M.E.; Pinto, M.. "Small molecules as chromatographic tools for HPLC enantiomeric resolution: Pirkle-type
chiral stationary phases evolution". Chromatographia 76 15-16 (2013): 871-897. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881142318&partnerID=MN8TOARS.
10.1007/s10337-013-2469-8
- Lima, R.T.; Seca, H.; Palmeira, A.; Fernandes, M.X.; Castro, F.; Correia-da-Silva, M.; Nascimento, M.S.J.; et al. "Sulfated
small molecules targeting EBV in Burkitt lymphoma: From in silico screening to the evidence of in vitro effect on viral episomal
DNA". Chemical Biology and Drug Design 81 5 (2013): 631-644. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876827905&partnerID=MN8TOARS.
10.1111/cbdd.12109
- Leão, M.; Gomes, S.; Pedraza-Chaverri, J.; MacHado, N.; Sousa, E.; Pinto, M.; Inga, A.; Pereira, C.; Saraiva, L.. "a-mangostin
and gambogic acid as potential inhibitors of the p53-MDM2 interaction revealed by a yeast approach". Journal of Natural
Products 76 4 (2013): 774-778. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876902872&partnerID=MN8TOARS.
10.1021/np400049j
- Silva, Madalena; Vieira, Luís M.; Almeida, Ana Paula; Silva, Artur M. S.; Seca, Ana M. L.; Barreto, Maria do Carmo; Neto,
Ana I.; et al. "Chemical study and biological activity evaluation of two Azorean Macroalgae: Ulva rigida and Gelidium microdon".
(2013): http://hdl.handle.net/10400.3/2163.
10.4172/2332-2632.1000102
- Palmeira, A.; Sousa, E.; Helena Vasconcelos, M.; Pinto, M.; Fernandes, M.X.. "Structure and Ligand-based design of P-glycoprotein
inhibitors: A historical perspective". Current Pharmaceutical Design 18 27 (2012): 4197-4214. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866309751&partnerID=MN8TOARS.
10.2174/138161212802430530
- Neves, M.P.; Lima, R.T.; Choosang, K.; Pakkong, P.; De São José Nascimento, M.; Vasconcelos, M.H.; Pinto, M.; Silva, A.M.S.;
Cidade, H.. "Synthesis of a natural chalcone and its prenyl analogs - Evaluation of tumor cell growth-inhibitory activities,
and effects on cell cycle and apoptosis". Chemistry and Biodiversity 9 6 (2012): 1133-1143. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862534164&partnerID=MN8TOARS.
10.1002/cbdv.201100190
- Fernandes, C.; Oliveira, L.; Tiritan, M.E.; Leitao, L.; Pozzi, A.; Noronha-Matos, J.B.; Correia-De-Sá, P.; Pinto, M.M.. "Synthesis
of new chiral xanthone derivatives acting as nerve conduction blockers in the rat sciatic nerve". European Journal of Medicinal
Chemistry 55 (2012): 1-11. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865764202&partnerID=MN8TOARS.
10.1016/j.ejmech.2012.06.049
- Palmeira, A.; Sousa, E.; Vasconcelos, M.H.; Pinto, M.M.. "Three decades of P-gp Inhibitors: Skimming through several generations
and scaffolds". Current Medicinal Chemistry 19 13 (2012): 1946-2025. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860535245&partnerID=MN8TOARS.
10.2174/092986712800167392
- Palmeira, A.; Vasconcelos, M.H.; Paiva, A.; Fernandes, M.X.; Pinto, M.; Sousa, E.. "Dual inhibitors of P-glycoprotein and
tumor cell growth: (Re)discovering thioxanthones". Biochemical Pharmacology 83 1 (2012): 57-68. http://www.scopus.com/inward/record.url?eid=2-s2.0-81855198003&partnerID=MN8TOARS.
10.1016/j.bcp.2011.10.004
- Neves, M.P.; Camões, A.; De São José Nascimento, M.; Cidade, H.; Sousa, M.E.; Pinto, M.M.M.. "Effects of a prenyl-baicalein
derivative on ER (+) MCF-7 and ER (-) MDA-MB-231 breast tumor cell lines". Medicinal Chemistry Research 21 10 (2012):
3154-3160. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866361437&partnerID=MN8TOARS.
10.1007/s00044-011-9848-1
- Belaz, K.R.A.; Denadai, M.; Almeida, A.P.; Lima, R.T.; Vasconcelos, M.H.; Pinto, M.M.; Cass, Q.B.; Oliveira, R.V.. "Enantiomeric
resolution of albendazole sulfoxide by semipreparative HPLC and in vitro study of growth inhibitory effects on human cancer
cell lines". Journal of Pharmaceutical and Biomedical Analysis 66 (2012): 100-108. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861222683&partnerID=MN8TOARS.
10.1016/j.jpba.2012.03.012
- Fernandes, C.; Tiritan, M.E.; Cass, Q.; Kairys, V.; Fernandes, M.X.; Pinto, M.. "Enantioseparation and chiral recognition
mechanism of new chiral derivatives of xanthones on macrocyclic antibiotic stationary phases". Journal of Chromatography
A 1241 (2012): 60-68. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860674472&partnerID=MN8TOARS.
10.1016/j.chroma.2012.04.011
- Paiva, A.M.; Sousa, M.E.; Camões, A.; Nascimento, M.S.J.; Pinto, M.M.M.. "Prenylated xanthones: Antiproliferative effects
and enhancement of the growth inhibitory action of 4-hydroxytamoxifen in estrogen receptor-positive breast cancer cell line".
Medicinal Chemistry Research 21 5 (2012): 552-558. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861841935&partnerID=MN8TOARS.
10.1007/s00044-011-9562-z
- Fernandes, C.; Brandão, P.; Santos, A.; Tiritan, M.E.; Afonso, C.; Cass, Q.B.; Pinto, M.M.. "Resolution and determination
of enantiomeric purity of new chiral derivatives of xanthones using polysaccharide-based stationary phases". Journal of
Chromatography A 1269 (2012): 143-153. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870339987&partnerID=MN8TOARS.
10.1016/j.chroma.2012.07.058
- Azevedo, C.M.G.; Afonso, C.M.M.; Pinto, M.M.M.. "Routes to xanthones: An update on the synthetic approaches". Current Organic
Chemistry 16 23 (2012): 2818-2867. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872562120&partnerID=MN8TOARS.
10.2174/138527212804546921
- Neves, M.P.; Cravo, S.; Lima, R.T.; Vasconcelos, M.H.; Nascimento, M.S.J.; Silva, A.M.S.; Pinto, M.; Cidade, H.; Corrêa, A.G..
"Solid-phase synthesis of 2'-hydroxychalcones. Effects on cell growth inhibition, cell cycle and apoptosis of human tumor
cell lines". Bioorganic and Medicinal Chemistry 20 1 (2012): 25-33. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855202674&partnerID=MN8TOARS.
10.1016/j.bmc.2011.11.042
- Pinto, E.; Afonso, C.; Duarte, S.; Vale-Silva, L.; Costa, E.; Sousa, E.; Pinto, M.. "Antifungal Activity of Xanthones: Evaluation
of their Effect on Ergosterol Biosynthesis by High-performance Liquid Chromatography". Chemical Biology and Drug Design
77 3 (2011): 212-222. http://www.scopus.com/inward/record.url?eid=2-s2.0-79651474308&partnerID=MN8TOARS.
10.1111/j.1747-0285.2010.01072.x
- Correia-Da-Silva, M.; Sousa, E.; Duarte, B.; Marques, F.; Cunha-Ribeiro, L.M.; Pinto, M.M.M.. "Dual anticoagulant/antiplatelet
persulfated small molecules". European Journal of Medicinal Chemistry 46 6 (2011): 2347-2358. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955585407&partnerID=MN8TOARS.
10.1016/j.ejmech.2011.03.016
- Correia-Da-Silva, M.; Sousa, E.; Duarte, B.; Marques, F.; Carvalho, F.; Cunha-Ribeiro, L.M.; Pinto, M.M.M.. "Flavonoids with
an oligopolysulfated moiety: A new class of anticoagulant agents". Journal of Medicinal Chemistry 54 1 (2011): 95-106.
http://www.scopus.com/inward/record.url?eid=2-s2.0-78651081744&partnerID=MN8TOARS.
10.1021/jm1013117
- Palmeira, A.; Sousa, E.; Fernandes, M.X.; Pinto, M.M.; Helena Vasconcelos, M.. "Multidrug resistance reversal effects of aminated
thioxanthones and interaction with cytochrome P450 3A4". Journal of Pharmacy and Pharmaceutical Sciences 15 1 (2011):
31-45. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856137888&partnerID=MN8TOARS.
- Palmeira, A.; Rodrigues, F.; Sousa, E.; Pinto, M.; Vasconcelos, M.H.; Fernandes, M.X.. "New uses for old drugs: Pharmacophore-based
screening for the discovery of P-glycoprotein inhibitors". Chemical Biology and Drug Design 78 1 (2011): 57-72. http://www.scopus.com/inward/record.url?eid=2-s2.0-79958812376&partnerID=MN8TOARS.
10.1111/j.1747-0285.2011.01089.x
- Correia-Da-Silva, M.; Sousa, E.; Duarte, B.; Marques, F.; Carvalho, F.; Cunha-Ribeiro, L.M.; Pinto, M.M.M.. "Polysulfated
xanthones: Multipathway development of a new generation of dual anticoagulant/antiplatelet agents". Journal of Medicinal
Chemistry 54 15 (2011): 5373-5384. http://www.scopus.com/inward/record.url?eid=2-s2.0-79961228634&partnerID=MN8TOARS.
10.1021/jm2006589
- Neves, M.P.; Cidade, H.; Pinto, M.; Silva, A.M.S.; Gales, L.; Damas, A.M.; Lima, R.T.; Vasconcelos, M.H.; Nascimento, M.D.S.J..
"Prenylated derivatives of baicalein and 3,7-dihydroxyflavone: Synthesis and study of their effects on tumor cell lines growth,
cell cycle and apoptosis". European Journal of Medicinal Chemistry 46 6 (2011): 2562-2574. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955635866&partnerID=MN8TOARS.
10.1016/j.ejmech.2011.03.047
- Pinto, O.; Sardinha, J.; Vaz, P.D.; Piedade, F.; Calhorda, M.J.; Abramovitch, R.; Nazareth, N.; et al. "Synthesis of tetrahydronaphthalene
lignan esters by intramolecular cyclization of ethyl p-azidophenyl-2-phenylalkanoates and evaluation of the growth inhibition
of human tumor cell lines". Journal of Medicinal Chemistry 54 9 (2011): 3175-3187. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955843003&partnerID=MN8TOARS.
10.1021/jm101182s
- Cazal, C.M.; Choosang, K.; Severino, V.G.P.; Soares, M.S.; Sarria, A.L.F.; Fernandes, J.B.; Silva, M.F.G.F.; et al. "Evaluation
of Effect of Triterpenes and Limonoids on Cell Growth, Cell Cycle and Apoptosis in Human Tumor Cell Lines". Anti-Cancer
Agents in Medicinal Chemistry 10 10 (2010): 769-776. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952740999&partnerID=MN8TOARS.
- Palmeira, A.; Paiva, A.; Sousa, E.; Seca, H.; Almeida, G.M.; Lima, R.T.; Fernandes, M.X.; Pinto, M.; Vasconcelos, M.H.. "Insights
into the in vitro antitumor mechanism of action of a new pyranoxanthone". Chemical Biology and Drug Design 76 1 (2010):
43-58. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953008434&partnerID=MN8TOARS.
10.1111/j.1747-0285.2010.00978.x
- Costa, E.; Sousa, E.; Nazareth, N.; Nascimento, M.S.J.; Pinto, M.M.M.. "Synthesis of xanthones and benzophenones as inhibitors
of tumor cell growth". Letters in Drug Design and Discovery 7 7 (2010): 487-493. http://www.scopus.com/inward/record.url?eid=2-s2.0-77958460956&partnerID=MN8TOARS.
10.2174/157018010791526250
- Auamcharoen, W.; Kijjoa, A.; Chandrapatya, A.; Pinto, M.M.; Silva, A.M.S.; Naengchomnong, W.; Herz, W.. "A new tetralone from
Diospyros cauliflora". Biochemical Systematics and Ecology 37 5 (2009): 690-692. http://www.scopus.com/inward/record.url?eid=2-s2.0-72749118489&partnerID=MN8TOARS.
10.1016/j.bse.2009.10.004
- Castanheiro, R.A.P.; Silva, A.M.S.; Campos, N.A.N.; Nascimento, M.S.J.; Pinto, M.M.M.. "Antitumor activity of some prenylated
xanthones". Pharmaceuticals 2 2 (2009): 33-43. http://www.scopus.com/inward/record.url?eid=2-s2.0-74549217779&partnerID=MN8TOARS.
10.3390/ph2020033
- Sousa, E.; Paiva, A.; Nazareth, N.; Gales, L.; Damas, A.M.; Nascimento, M.S.J.; Pinto, M.. "Bromoalkoxyxanthones as promising
antitumor agents: Synthesis, crystal structure and effect on human tumor cell lines". European Journal of Medicinal Chemistry
44 9 (2009): 3830-3835. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650578617&partnerID=MN8TOARS.
10.1016/j.ejmech.2009.04.011
- Castanheiro, R.A.P.; Pinto, M.M.M.; Cravo, S.M.M.; Pinto, D.C.G.A.; Silva, A.M.S.; Kijjoa, A.. "Improved methodologies for
synthesis of prenylated xanthones by microwave irradiation and combination of heterogeneous catalysis (K10 clay) with microwave
irradiation". Tetrahedron 65 19 (2009): 3848-3857. http://www.scopus.com/inward/record.url?eid=2-s2.0-63649133722&partnerID=MN8TOARS.
10.1016/j.tet.2009.03.019
- Pinto, M.M.M.; Castanheiro, R.A.P.. "Synthesis of prenylated xanthones: An overview". Current Organic Chemistry 13
12 (2009): 1215-1240. http://www.scopus.com/inward/record.url?eid=2-s2.0-73049118632&partnerID=MN8TOARS.
10.2174/138527209788921747
- Gales, L.; Castanheiro, R.A.P.; Pinto, M.M.M.; Damas, A.M.. "1-Hydr-oxy-3-(3-methyl-but-2-en-yloxy)xanthone". Acta Crystallographica
Section E: Structure Reports Online 65 11 (2009): http://www.scopus.com/inward/record.url?eid=2-s2.0-70449450672&partnerID=MN8TOARS.
10.1107/S1600536809040069
- Kijjoa, A.; Gonzalez, M.J.; Pinto, M.M.; Nascimento, M.S.J.; Campos, N.; Mondranondra, I.-O.; Silva, A.M.S.; Eaton, G.; Herz,
W.. "Cytotoxicity of prenylated xanthones and other constituents from the wood of Garcinia merguensis". Planta Medica
74 8 (2008): 864-866. http://www.scopus.com/inward/record.url?eid=2-s2.0-47249154002&partnerID=MN8TOARS.
10.1055/s-2008-1074544
- Teixeira, M.; Afonso, C.M.M.; Pinto, M.M.M.; Barbosa, C.M.. "Development and validation of an HPLC method for the quantitation
of 1,3-dihydroxy-2-methyixanthone in biodegradable nanoparticles". Journal of Chromatographic Science 46 6 (2008):
472-478. http://www.scopus.com/inward/record.url?eid=2-s2.0-47549098832&partnerID=MN8TOARS.
- Oliveira-Campos, A.M.F.; Sivasubramanian, A.; Rodrigues, L.M.; Seijas, J.A.; Vázquez-Tato, M.P.; Peixoto, F.; Abreu, C.G.;
et al. "Substituted pyrazolo[3,4-d]pyrimidines: Microwave-assisted, solvent-free synthesis and biological evaluation". Helvetica
Chimica Acta 91 7 (2008): 1336-1345. http://www.scopus.com/inward/record.url?eid=2-s2.0-55449128000&partnerID=MN8TOARS.
10.1002/hlca.200890145
- Gupta, S.; Rodrigues, L.M.; Esteves, A.P.; Oliveira-Campos, A.M.F.; Nascimento, M.S.J.; Nazareth, N.; Cidade, H.; et al. "Synthesis
of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors". European Journal of Medicinal Chemistry
43 4 (2008): 771-780. http://www.scopus.com/inward/record.url?eid=2-s2.0-41549164049&partnerID=MN8TOARS.
10.1016/j.ejmech.2007.06.002
- Dethoup, T.; Manoch, L.; Kijjoa, A.; Pinto, M.; Gales, L.; Damas, A.M.; Silva, A.M.S.; Eaton, G.; Herz, W.. "Merodrimanes
and other constituents from Talaromyces thailandiasis". Journal of Natural Products 70 7 (2007): 1200-1202. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548046228&partnerID=MN8TOARS.
10.1021/np0680578
- Portela, C.; Afonso, C.M.M.; Pinto, M.M.M.; Lopes, D.; Nogueira, F.; do Rosário, V.. "Synthesis and antimalarial properties
of new chloro-9H-xanthones with an aminoaikyl side chain". Chemistry and Biodiversity 4 7 (2007): 1508-1519. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547553741&partnerID=MN8TOARS.
10.1002/cbdv.200790130
- Oliveira, A.M.A.G.; Oliveira-Campos, A.M.F.; Rodrigues, L.M.; Raposo, M.M.M.; Machado, A.E.H.; Nascimento, M.S.J.; Nazareth,
N.; Pinto, M.. "Synthesis and antitumor evaluation of benzopsoralen analogues". Chemistry and Biodiversity 4 5 (2007):
980-990. http://www.scopus.com/inward/record.url?eid=2-s2.0-34250687525&partnerID=MN8TOARS.
10.1002/cbdv.200790089
- Kijjoa, A.; Wattanadilok, R.; Campos, N.; Nascimento, M.S.J.; Pinto, M.; Herz, W.. "Anticancer activity evaluation of kuanoniamines
A and C isolated from the marine sponge Oceanapia sagittaria, collected from the Gulf of Thailand". Marine Drugs 5
2 (2007): 6-22. http://www.scopus.com/inward/record.url?eid=2-s2.0-34347258181&partnerID=MN8TOARS.
10.3390/md20070002
- Wattanadilok, R.; Sawangwong, P.; Rodrigues, C.; Cidade, H.; Pinto, M.; Pinto, E.; Silva, A.; Kijjoa, A.. "Antifungal activity
evaluation of the constituents of Haliclona baeri and Haliclona cymaeformis, collected from the Gulf of Thailand". Marine
Drugs 5 2 (2007): 40-51. http://www.scopus.com/inward/record.url?eid=2-s2.0-34347227475&partnerID=MN8TOARS.
10.3390/md20070005
- Suedee, A.; Mondranondra, I.-O.; Kijjoa, A.; Pinto, M.; Nazareth, N.; Nascimento, M.S.J.; Silva, A.M.S.; Herz, W.. "Constituents
of Polyalthia jucunda and their cytotoxic effect on human cancer cell lines". Pharmaceutical Biology 45 7 (2007): 575-579.
http://www.scopus.com/inward/record.url?eid=2-s2.0-34548329245&partnerID=MN8TOARS.
10.1080/13880200701501300
- Castanheiro, R.A.P.; Pinto, M.M.M.; Silva, A.M.S.; Cravo, S.M.M.; Gales, L.; Damas, A.M.; Nazareth, N.; Nascimento, M.S.J.;
Eaton, G.. "Dihydroxyxanthones prenylated derivatives: Synthesis, structure elucidation, and growth inhibitory activity on
human tumor cell lines with improvement of selectivity for MCF-7". Bioorganic and Medicinal Chemistry 15 18 (2007):
6080-6088. http://www.scopus.com/inward/record.url?eid=2-s2.0-34447630284&partnerID=MN8TOARS.
10.1016/j.bmc.2007.06.037
- Wilairat, R.; Kijjoa, A.; Pinto, M.; Nascimento, M.S.J.; Silva, A.M.S.; Eaton, G.; Herz, W.. "Constituents of Schisandra verruculosa
and their cytotoxic effect on human cancer cell lines". Pharmaceutical Biology 44 6 (2006): 411-415. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747754866&partnerID=MN8TOARS.
10.1080/13880200600794105
- Pedro, M.; Lourenço, C.F.; Cidade, H.; Kijjoa, A.; Pinto, M.; Nascimento, M.S.J.. "Effects of natural prenylated flavones
in the phenotypical ER (+) MCF-7 and ER (-) MDA-MB-231 human breast cancer cells". Toxicology Letters 164 1 (2006):
24-36. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646096970&partnerID=MN8TOARS.
10.1016/j.toxlet.2005.11.007
- Sousa, M.E.; Tiritan, M.E.; Belaz, K.R.A.; Pedro, M.; Nascimento, M.S.J.; Cass, Q.B.; Pinto, M.M.M.. "Multimilligram enantioresolution
of low-solubility xanthonolignoids on polysaccharide chiral stationary phases using a solid-phase injection system". Journal
of Chromatography A 1120 1-2 (2006): 75-81. http://www.scopus.com/inward/record.url?eid=2-s2.0-33744985766&partnerID=MN8TOARS.
10.1016/j.chroma.2005.12.071
- Oliveira, A.M.A.G.; Raposo, M.M.M.; Oliveira-Campos, A.M.F.; Machado, A.E.H.; Puapairoj, P.; Pedro, M.; Nascimento, M.S.J.;
et al. "Psoralen analogues: synthesis, inhibitory activity of growth of human tumor cell lines and computational studies".
European Journal of Medicinal Chemistry 41 3 (2006): 367-372. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646003889&partnerID=MN8TOARS.
10.1016/j.ejmech.2005.10.016
- Puapairoj, P.; Naengchomnong, W.; Kijjoa, A.; Pinto, M.M.; Pedro, M.; Nascimento, M.S.J.; Silva, A.M.S.; Herz, W.. "Cytotoxic
activity of lupane-type triterpenes from Glochidion sphaerogynum and Glochidion eriocarpum two of which induce apoptosis".
Planta Medica 71 3 (2005): 208-213. http://www.scopus.com/inward/record.url?eid=2-s2.0-16444374823&partnerID=MN8TOARS.
10.1055/s-2005-837818
- Wilairat, R.; Manosroi, J.; Manosroi, A.; Kijjoa, A.; Nascimento, M.S.J.; Pinto, M.; Silva, A.M.S.; Eaton, G.; Herz, W.. "Cytotoxicities
of xanthones and cinnamate esters from Hypericum hookerianum". Planta Medica 71 7 (2005): 680-682. http://www.scopus.com/inward/record.url?eid=2-s2.0-23644442233&partnerID=MN8TOARS.
10.1055/s-2005-871276
- Teixeira, M.; Alonso, M.J.; Pinto, M.M.M.; Barbosa, C.M.. "Development and characterization of PLGA nanospheres and nanocapsules
containing xanthone and 3-methoxyxanthone". European Journal of Pharmaceutics and Biopharmaceutics 59 3 (2005): 491-500.
http://www.scopus.com/inward/record.url?eid=2-s2.0-14844303762&partnerID=MN8TOARS.
10.1016/j.ejpb.2004.09.002
- Pinto, M.M.M.. "Editorial". Current Medicinal Chemistry 12 21 (2005): http://www.scopus.com/inward/record.url?eid=2-s2.0-26044432820&partnerID=MN8TOARS.
10.2174/092986705774370745
- Teixeira, M.; Ceroqueira, F.; Barbosa, C.M.; Nascimento, M.S.J.; Pinto, M.. "Improvement of the inhibitory effect of xanthones
on NO production by encapsulation in PLGA nanocapsules". Journal of Drug Targeting 13 2 (2005): 129-135. http://www.scopus.com/inward/record.url?eid=2-s2.0-17444407527&partnerID=MN8TOARS.
10.1080/10611860400027717
- Sousa, M.E.; Pinto, M.M.M.. "Synthesis of xanthones: An overview". Current Medicinal Chemistry 12 21 (2005): 2447-2479.
http://www.scopus.com/inward/record.url?eid=2-s2.0-26044481179&partnerID=MN8TOARS.
10.2174/092986705774370736
- Maia, F.; Almeida, M.D.R.; Gales, L.; Kijjoa, A.; Pinto, M.M.M.; Saraiva, M.J.; Damas, A.M.. "The binding of xanthone derivatives
to transthyretin". Biochemical Pharmacology 70 12 (2005): 1861-1869. http://www.scopus.com/inward/record.url?eid=2-s2.0-27744528447&partnerID=MN8TOARS.
10.1016/j.bcp.2005.09.012
- Pinto, M.M.M.; Sousa, M.E.; Nascimento, M.S.J.. "Xanthone derivatives: New insights in biological activities". Current
Medicinal Chemistry 12 21 (2005): 2517-2538. http://www.scopus.com/inward/record.url?eid=2-s2.0-26044467360&partnerID=MN8TOARS.
10.2174/092986705774370691
- Gales, L.; Sousa, M.E.; Pinto, M.M.M.; Damas, A.M.. "3,4-Dihydroxy-9H-xanthen-9-one trihydrate". Acta Crystallographica
Section E: Structure Reports Online 61 7 (2005): http://www.scopus.com/inward/record.url?eid=2-s2.0-32244442730&partnerID=MN8TOARS.
10.1107/S1600536805018994
- Portela, C.; Afonso, C.M.M.; Pinto, M.M.M.; Ramos, M.J.. "Definition of an electronic profile of compounds with inhibitory
activity against hematin aggregation in malaria parasite". Bioorganic and Medicinal Chemistry 12 12 (2004): 3313-3321.
http://www.scopus.com/inward/record.url?eid=2-s2.0-2542443667&partnerID=MN8TOARS.
10.1016/j.bmc.2004.03.060
- Cerqueira, F.; Cordeiro-Da-Silva, A.; Gaspar-Marques, C.; Simões, F.; Pinto, M.M.M.; Nascimento, M.S.J.. "Effect of abietane
diterpenes from Plectranthus grandidentatus on T- and B-lymphocyte proliferation". Bioorganic and Medicinal Chemistry
12 1 (2004): 217-223. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346040413&partnerID=MN8TOARS.
10.1016/j.bmc.2003.10.006
- Nascimento, M.S.J.; Pedro, M.; Cerqueira, F.; Bastos, M.; Vieira, L.M.; Kijjoa, A.; Pinto, M.M.M.. "Effect of natural 2,5-diaryl-3,4-dimethyltetrahydrofuran
lignans on complement activation, lymphocyte proliferation, and growth of tumor cell lines". Pharmaceutical Biology
42 6 (2004): 449-453. http://www.scopus.com/inward/record.url?eid=2-s2.0-11244292562&partnerID=MN8TOARS.
10.1080/13880200490894824
- Sousa, E.P.; Tiritan, M.E.; Oliveira, R.V.; Afonso, C.M.M.; Cass, Q.B.; Pinto, M.M.M.. "Enantiomeric Resolution of Kielcorin
Derivatives by HPLC on Polysaccharide Stationary Phases Using Multimodal Elution". Chirality 16 5 (2004): 279-285.
http://www.scopus.com/inward/record.url?eid=2-s2.0-1942540475&partnerID=MN8TOARS.
10.1002/chir.20031
- Moiteiro, C.; Manta, C.; Justino, F.; Tavares, R.; Curto, M.J.M.; Pedro, M.; Nascimento, M.S.J.; Pinto, M.. "Hemisynthetic
secofriedelane triterpenes with inhibitory activity against the growth of human tumor cell lines in vitro". Journal of
Natural Products 67 7 (2004): 1193-1196. http://www.scopus.com/inward/record.url?eid=2-s2.0-3242771184&partnerID=MN8TOARS.
10.1021/np0498915
- Teixeira, M.; Pinto, M.M.M.; Gonçalves Barbosa, C.M.. "Validation of a spectrophotometric method for quantification of xanthone
in biodegradable nanoparticles". Pharmazie 59 4 (2004): 257-259. http://www.scopus.com/inward/record.url?eid=2-s2.0-1842683160&partnerID=MN8TOARS.
- Teixeira, M.; Afonso, C.M.M.; Pinto, M.M.M.M.; Barbosa, C.M.. "A validated HPLC method for the assay of xanthone and 3-methoxyxanthone
in PLGA nanocapsules". Journal of Chromatographic Science 41 7 (2003): 371-376. http://www.scopus.com/inward/record.url?eid=2-s2.0-0041471094&partnerID=MN8TOARS.
- Gigante, B.; Santos, C.; Silva, A.M.; Curto, M.J.M.; Nascimento, M.S.J.; Pinto, E.; Pedro, M.; et al. "Catechols from abietic
acid: Synthesis and evaluation as bioactive compounds". Bioorganic and Medicinal Chemistry 11 8 (2003): 1631-1638.
http://www.scopus.com/inward/record.url?eid=2-s2.0-12244279082&partnerID=MN8TOARS.
10.1016/S0968-0896(03)00063-4
- Cerqueira, F.; Watanadilok, R.; Sonchaeng, P.; Kijjoa, A.; Pinto, M.; Van Ufford, H.Q.; Kroes, B.; Beukelman, C.; Nascimento,
M.S.J.. "Clionasterol: A potent inhibitor of complement component C1". Planta Medica 69 2 (2003): 174-176. http://www.scopus.com/inward/record.url?eid=2-s2.0-0345505660&partnerID=MN8TOARS.
10.1055/s-2003-37719
- Portela, C.; Afonso, C.M.M.; Pinto, M.M.M.; Ramos, M.J.. "Computational studies of new potential antimalarial compounds -
Stereoelectronic complementarity with the receptor". Journal of Computer-Aided Molecular Design 17 9 (2003): 583-595.
http://www.scopus.com/inward/record.url?eid=2-s2.0-0346882949&partnerID=MN8TOARS.
10.1023/B:JCAM.0000005754.24588.a0
- Saraiva, L.; Fresco, P.; Pinto, E.; Sousa, E.; Pinto, M.; Gonçalves, J.. "Inhibition of protein kinase C by synthetic xanthone
derivatives". Bioorganic and Medicinal Chemistry 11 7 (2003): 1215-1225. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037375620&partnerID=MN8TOARS.
10.1016/S0968-0896(02)00641-7
- Saraiva, L.; Fresco, P.; Pinto, E.; Sousa, E.; Pinto, M.; Gonçalves, J.. "Inhibition of a, ßI, d, ¿ and ¿ protein kinase C
isoforms by xanthonolignoids". Journal of Enzyme Inhibition and Medicinal Chemistry 18 4 (2003): 357-370. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042697461&partnerID=MN8TOARS.
10.1080/147563601000118400
- Pinto, M.M.M.; Sousa, E.P.. "Natural and synthetic xanthonolognoids: Chemistry and biological activities". Current Medicinal
Chemistry 10 1 (2003): 1-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037241449&partnerID=MN8TOARS.
10.2174/0929867033368574
- Sousa, M.E.; Afonso, C.M.M.; Pinto, M.M.M.. "Quantitative analysis of Kielcorins in biomimetic synthesis by liquid chromatography/UV
detection". Journal of Liquid Chromatography and Related Technologies 26 1 (2003): 29-41. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037279266&partnerID=MN8TOARS.
10.1081/JLC-120017150
- Portela, C.; Afonso, C.M.M.; Pinto, M.M.M.; Ramos, M.J.. "Receptor-drug association studies in the inhibition of the hematin
aggregation process of malaria". FEBS Letters 547 1-3 (2003): 217-222. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038492779&partnerID=MN8TOARS.
10.1016/S0014-5793(03)00692-6
- Kijjoa, A.; Bessa, J.; Pinto, M.M.M.; Anatachoke, C.; Silva, A.M.S.; Eaton, G.; Herz, W.. "Polyoxygenated cyclohexene derivatives
from Ellipeiopsis cherrevensis". Phytochemistry 59 5 (2002): 543-549. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037017451&partnerID=MN8TOARS.
10.1016/S0031-9422(01)00465-4
- Gonzalez, M.J.; Pinto, M.M.M.; Kijjoa, A.; Kengthong, S.; Mondanondra, I.-O.; Silva, A.; Eaton, G.; Herz, W.. "5,7-Dihydroxychromones
and 8-hydroxytetrahydrochromones from Horsfieldia irya". Phytochemistry 61 8 (2002): 995-998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036900718&partnerID=MN8TOARS.
10.1016/S0031-9422(02)00381-3
- Marques, C.G.; Pedro, M.; Simões, M.F.A.; Nascimento, M.S.J.; Pinto, M.M.M.; Rodriguez, B.. "Effect of abietane diterpenes
from Plectranthus grandidentatus on the growth of human cancer cell lines". Planta Medica 68 9 (2002): 839-840. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036747070&partnerID=MN8TOARS.
10.1055/s-2002-34407
- Sousa, E.P.; Silva, A.M.S.; Pinto, M.M.M.; Pedro, M.M.; Cerqueira, F.A.M.; Nascimento, M.S.J.. "Isomeric kielcorins and dihydroxyxanthones:
Synthesis, structure elucidation, and inhibitory activities of growth of human cancer cell lines and on the proliferation
of human lymphocytes in vitro". Helvetica Chimica Acta 85 9 (2002): 2862-2876. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036397646&partnerID=MN8TOARS.
10.1002/1522-2675(200209)85:9<2862::AID-HLCA2862>3.0.CO;2-R
- Saraiva, L.; Fresco, P.; Pinto, E.; Sousa, E.; Pinto, M.; Gonçalves, J.. "Synthesis and in vivo modulatory activity of protein
kinase C of xanthone derivatives". Bioorganic and Medicinal Chemistry 10 10 (2002): 3219-3227. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036336285&partnerID=MN8TOARS.
10.1016/S0968-0896(02)00169-4
- Pedro, M.; Cerqueira, F.; Sousa, M.E.; Nascimento, M.S.J.; Pinto, M.. "Xanthones as inhibitors of growth of human cancer cell
lines and their effects on the proliferation of human lymphocytes in vitro". Bioorganic and Medicinal Chemistry 10
12 (2002): 3725-3730. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036973288&partnerID=MN8TOARS.
10.1016/S0968-0896(02)00379-6
- Cidade, H.M.; Nacimento, M.S.; Pinto, M.M.M.; Kijjoa, A.; Silva, A.M.S.; Herz, W.. "Artelastocarpin and carpelastofuran, two
new flavones, and cytotoxicities of prenyl flavonoids from Artocarpus elasticus against three cancer cell lines". Planta
Medica 67 9 (2001): 867-870. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035678932&partnerID=MN8TOARS.
10.1055/s-2001-18845
- Guerre, C.; Thull, U.; Gaillard, P.; Carrupt, P.-A.; Testa, B.; Fernandes, E.; Silva, F.; et al. "Natural and synthetic xanthones
as monoamine oxidase inhibitors: Biological assay and 3D-QSAR". Helvetica Chimica Acta 84 3 (2001): 552-570. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035048669&partnerID=MN8TOARS.
10.1002/1522-2675(20010321)84:3<552::AID-HLCA552>3.0.CO;2-X
- Gales, L.; De Sousa, M.E.; Pinto, M.M.M.; Kijjoa, A.; Damas, A.M.. "Naturally occurring 1,2,8-trimethoxy-xanthone and biphenyl
ether intermediates leading to 1,2-dimethoxy-xanthone". Acta Crystallographica Section C: Crystal Structure Communications
57 11 (2001): 1319-1323. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035498028&partnerID=MN8TOARS.
- Moiteiro, C.; Justino, F.; Tavares, R.; Marcelo-Curto, M.J.; Florêncio, M.H.; Nascimento, M.S.J.; Pedro, M.; Cerqueira, F.;
Pinto, M.M.M.. "Synthetic secofriedelane and friedelane derivatives as inhibitors of human lymphocyte proliferation and growth
of human cancer cell lines in vitro". Journal of Natural Products 64 10 (2001): 1273-1277. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034765209&partnerID=MN8TOARS.
10.1021/np010217m
- Kijjoa, A.; Gonzalez, M.J.; Pinto, M.M.M.; Silva, A.M.S.; Anantachoke, C.; Herz, W.. "Xanthones from Calophyllum teysmannii
var. inophylloide". Phytochemistry 55 7 (2000): 833-836. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034623793&partnerID=MN8TOARS.
10.1016/S0031-9422(00)00289-2
- Kijjoa, A.; Gonzalez, M.J.; Afonso, C.M.; Pinto, M.M.M.; Anantachoke, C.; Herz, W.. "Xanthones from Calophyllum teysmannii
var. inophylloide". Phytochemistry 53 8 (2000): 1021-1024. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034716778&partnerID=MN8TOARS.
10.1016/S0031-9422(99)00520-8
- Gonzalez, M.J.; Nascimento, M.S.J.; Cidade, H.M.; Pinto, M.M.M.; Kijjoa, A.; Anantachoke, C.; Silva, A.M.S.; et al. "Immunomodulatory
activity of xanthones from Calophyllum teysmannii var. inuphylloide". Planta Medica 65 4 (1999): 368-371. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033045834&partnerID=MN8TOARS.
10.1055/s-2006-960790
- Fernandes, E.G.R.; Pinto, M.M.M.; Silva, A.M.S.; Cavaleiro, J.A.S.; Gottlieb, O.R.. "Synthesis and structural elucidation
of xanthonolignoids: Trans-(±)- kielcorin B and trans-(±)-isokielcorin B". Heterocycles 51 4 (1999): 821-828. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033117467&partnerID=MN8TOARS.
- Fernandes, E.G.R.; Silva, A.M.S.; Cavaleiro, J.A.S.; Silva, F.M.; Borges, M.F.M.; Pinto, M.M.M.. "1H and 13C NMR spectroscopy
of mono-, di-, tri- and tetrasubstituted xanthones". Magnetic Resonance in Chemistry 36 4 (1998): 305-309. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032377382&partnerID=MN8TOARS.
- Nascimento, M.S.J.; Pinto, M.M.M.; Vieira, L.M.; Kijjoa, A.; Silva, A.M.S.; Kroes, B.H.; Labadie, R.P.. "Anticomplementary
activity of dolabranes from Endospermum diadenum". Pharmaceutical and Pharmacological Letters 8 2 (1998): 93-96. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031947160&partnerID=MN8TOARS.
- Kijjoa, A.; José, M.; Gonzalez, T.G.; Pinto, M.M.M.; Damas, A.M.; Mondranondra, I.-O.; Silva, A.M.S.; Herz, W.. "Xanthones
from Cratoxylum maingayi". Phytochemistry 49 7 (1998): 2159-2162. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031673130&partnerID=MN8TOARS.
10.1016/S0031-9422(98)00381-1
- Damas, A.M.; Roleira, F.F.; Pinto, M.M.M.. "2-[2-(hydroxyethyl)phenoxy]benzoic acid". Acta Crystallographica Section C:
Crystal Structure Communications 53 8 (1997): 1143-1145. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031207195&partnerID=MN8TOARS.
- Pinto, M.; Nascimento, M.S.J.; Gonzalez, M.J.; Mondranondra, I.-O.. "Anticomplementary activity and constituents of Cratoxylum
maingayi DYER". Pharmaceutical and Pharmacological Letters 7 2-3 (1997): 128-130. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030869897&partnerID=MN8TOARS.
- Pinto, M.; Nascimento, M.S.J.. "Anticomplementary activity of hydroxy- and methoxyxanthones". Pharmaceutical and Pharmacological
Letters 7 2-3 (1997): 125-127. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030773241&partnerID=MN8TOARS.
- Nascimento, M.S.J.; Cidade, H.; Pinto, M.; Kijjoa, A.. "Anticomplementary activity of prenylated flavones from Artocarpus
elasticus". Pharmaceutical and Pharmacological Letters 7 2-3 (1997): 135-137. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030758458&partnerID=MN8TOARS.
- Damas, A.M.; Kijjoa, A.; Pinto, M.. "Two dolabrane-type diterpenoids". Acta Crystallographica Section C: Crystal Structure
Communications 53 6 (1997): 755-757. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031168467&partnerID=MN8TOARS.
- Payá, M.; Ferrándiz, M.L.; Erradi, F.; Terencio, M.C.; Kijjoa, A.; Pinto, M.M.M.; Alcaraz, M.J.. "Inhibition of inflammatory
responses by a series of novel dolabrane derivatives". European Journal of Pharmacology 312 1 (1996): 97-105. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030593749&partnerID=MN8TOARS.
10.1016/0014-2999(96)00468-2
- Kijjoa, A.; Cidade, H.M.; Pinto, M.M.M.; Gonzalez, M.J.T.G.; Anantachoke, C.; Gedris, T.E.; Herz, W.. "Prenylflavonoids from
Artocarpus elasticus". Phytochemistry 43 3 (1996): 691-694. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030267084&partnerID=MN8TOARS.
10.1016/0031-9422(96)00293-2
- Fernandes, E.R.; Carvalho, F.D.; Remiao, F.G.; Bastos, L.M.; Pinto, M.M.; Gottlieb, O.R.. "Hepatoprotective activity of xanthones
and xanthonolignoids against tert-Butylhydroperoxide-Induced toxicity in isolated rat hepatocytes - Comparison with silybin".
Pharmaceutical Research 12 11 (1995): 1756-1760. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029620247&partnerID=MN8TOARS.
10.1023/A:1016230125496
- Kijjoa, A.; Pinto, M.M.M.; Anantachoke, C.; Gedris, T.E.; Herz, W.. "Dolabranes from Endospermum diadenum". Phytochemistry
40 1 (1995): 191-193. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028868109&partnerID=MN8TOARS.
10.1016/0031-9422(95)00253-4
- Kijjoa, A.; Pinto, M.M.M.; Do Carmo Carreiras, M.; Gottlieb, H.E.; Hezroni-Langerman, D.; Gottlieb, O.R.. "An unusual, dibenzo-cycloheptatriene
based, flavonoid from Ocotea foetens". Natural Product Letters 4 2 (1994): 85-92. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028211251&partnerID=MN8TOARS.
- Bastos, M.M.S.M.; Kijjoa, A.; Pinto, M.M.M.. "Constituents of Centaurea ornata ssp. ornata". Fitoterapia 65 2 (1994):
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028233278&partnerID=MN8TOARS.
- Kijjoa, A.; Polónia, M.A.; Pinto, M.M.M.; Kitiratakarn, T.; Gedris, T.E.; Herz, W.. "Dolabranes from Endospermum diadenum".
Phytochemistry 37 1 (1994): 197-200. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028093998&partnerID=MN8TOARS.
10.1016/0031-9422(94)85024-0
- Borges, M.F.M.; Pinto, M.M.M.. "Separation of the diastereoisomers of ethyl esters of caffeic, ferulic, and isoferulic acids
by thin-layer and high performance liquid chromatography". Journal of Liquid Chromatography 17 5 (1994): 1125-1139.
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028215114&partnerID=MN8TOARS.
- Borges, M.F.M.; Roleira, M.F.; Pinto, M.M.M.. "Simultaneous isocratic HPLC separation of the diasteroisomers of caffeic, ferulic,
and isoferulic acids and related coumarins". Journal of Liquid Chromatography 16 1 (1993): 149-160. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027402382&partnerID=MN8TOARS.
- Gonzaléz, M.J.T.G.; Pinto, M.M.M.; Kijjoa, A.; Anantachoke, C.; Herz, W.. "Stilbenes and other constituents of Knema austrosiamensis".
Phytochemistry 32 2 (1993): 433-438. http://www.scopus.com/inward/record.url?eid=2-s2.0-0000270448&partnerID=MN8TOARS.
10.1016/S0031-9422(00)95010-6
- Thull, U.; Kneubuhler, S.; Testa, B.; Borges, M.F.M.; Pinto, M.M.M.. "Substituted xanthones as selective and reversible monoamine
oxidase A (MAO-A) inhibitors". Pharmaceutical Research 10 8 (1993): 1187-1190. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027265461&partnerID=MN8TOARS.
10.1023/A:1018924503552
- Kijjoa, A.; Pinto, M.M.M.; Pinho, P.M.M.; Herz, W.. "Clerodanes from Polyalthia viridis". Phytochemistry 34 2 (1993):
457-460. http://www.scopus.com/inward/record.url?eid=2-s2.0-0000678595&partnerID=MN8TOARS.
10.1016/0031-9422(93)80030-V
- Borges, M.F.M.; Roleira, F.M.F.; Pinto, M.M.M.. "Erratum: Isocratic HPLC separation of scopoletin and cis/trans isomers of
ferulic acid as well as isoscopoletin and cis/trans isomers of isoferulic acid (J. Liquid Chromat. 14 (12), (1991) 2307-2316)".
Journal of Liquid Chromatography 15 2 (1992): http://www.scopus.com/inward/record.url?eid=2-s2.0-0026536754&partnerID=MN8TOARS.
- Pinho, P.M.M.; Pinto, M.M.M.; Kijjoa, A.; Pharadai, K.; Díaz, J.G.; Herz, W.. "Protoberberine alkaloids from Coscinium fenestratum".
Phytochemistry 31 4 (1992): 1403-1407. http://www.scopus.com/inward/record.url?eid=2-s2.0-0007050730&partnerID=MN8TOARS.
10.1016/0031-9422(92)80301-T
- Borges, F.; Pinto, M.. "Synthesis of coumarins and derivatives. Biomimetic synthesis of esculetin and halogenated derivatives".
Helvetica Chimica Acta 75 4 (1992): 1061-1068. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026777064&partnerID=MN8TOARS.
10.1002/hlca.19920750409
- Kijjoa, A.; Gonzalez, M.J.T.G.; Pinto, M.M.M.; Monanondra, I.-O.; Herz, W.. "Constituents of Knema laurina and Knema tenuinervia
ssp. setosa". Planta Medica 57 6 (1991): 575-577. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026337107&partnerID=MN8TOARS.
- Borges, M.F.M.; Roleira, F.M.F.; Pinto, M.M.M.. "Isocratic HPLC separation of scopoletin and cis/trans isomers of ferulic
acid as well as isoscopoletin and cis/trans isomers of isoferulic acid". Journal of Liquid Chromatography 14 12 (1991):
2307-2316. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025733730&partnerID=MN8TOARS.
- Polonia, M.A.J.; Carneiro, A.F.; Pinto, M.M.M.. "Quantification of usnic acid in Usnea florida by densitometric high performance
thin layer chromatography". Journal of Liquid Chromatography 14 8 (1991): 1447-1452. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025759264&partnerID=MN8TOARS.
- Pinto, M.M.M.; Kijjoa, A.; Mondranondra, I.-O.; Herz, W.. "Biphenyl type lignans and costunolide from Manglietia garrettii".
Planta Medica 56 4 (1990): 417-418. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025012196&partnerID=MN8TOARS.
- Kijjoa, A.; Pinto, M.M.M.; Pinho, P.M.M.; Tantisewie, B.; Herz, W.. "Clerodane derivatives from Polyalthia viridis". Phytochemistry
29 2 (1990): 653-655. http://www.scopus.com/inward/record.url?eid=2-s2.0-0000371484&partnerID=MN8TOARS.
10.1016/0031-9422(90)85137-5
- Pinto, M.M.M.; Kijjoa, A.; Mondranondra, I.-o.; Gutiérrez, A.B.; Herz, W.. "Lignans and other constituents of knema furfuracea".
Phytochemistry 29 6 (1990): 1985-1988. http://www.scopus.com/inward/record.url?eid=2-s2.0-0007694273&partnerID=MN8TOARS.
10.1016/0031-9422(90)85052-H
- Kijjoa, A.; Pinto, M.M.M.; Tantisewie, B.; Herz, W.. "A biphenyl type neolignan and a biphenyl ether from Magnolia henryi".
Phytochemistry 28 4 (1989): 1284-1286. http://www.scopus.com/inward/record.url?eid=2-s2.0-0000733854&partnerID=MN8TOARS.
10.1016/0031-9422(89)80237-7
- Borges, M.F.M.; Pinto, M.M.M.. "Isocratic high performance liquid chromatography separation of esculetin and cis/trans isomers
of caffeic acid". Journal of Liquid Chromatography 12 12 (1989): 2345-2354. http://www.scopus.com/inward/record.url?eid=2-s2.0-0024832758&partnerID=MN8TOARS.
- Pinto, Madalena. "A New Linalool Derivative and other Constituents from Piper ribesoides". Planta Medica (1989): https://www.thieme-connect.com/DOI/DOI?10.1055/s-2006-961923.
10.1055/s-2006-961923
- Pinto, M.M.M.; Kijjoa, A.; Tantisewiet, B.; Yoshida, M.; Gottlieb, O.R.. "Arylalkanones from Horsfieldia glabra". Phytochemistry
27 12 (1988): 3988-3989. http://www.scopus.com/inward/record.url?eid=2-s2.0-0000461837&partnerID=MN8TOARS.
10.1016/0031-9422(88)83067-X
- Gonzalez, M.J.; Pinto, M.M.M.; Kijjoa, A.; Tantisewie, B.. "Chemical constituents of seeds of Horsfieldia glabra". Fitoterapia
59 6 (1988): 486-487. http://www.scopus.com/inward/record.url?eid=2-s2.0-0024264264&partnerID=MN8TOARS.
- Pinto, Madalena. "Chemical Constituents of Piper ribesoides". Fitoterapia (1988):
- Pinto, Madalena. "Chemical Constituents of Piper ribesoides". Fitoterapia (1988):
- Pinto, Madalena. "Xanthonolignoides from Kielmeyera coriacea". Phytochemistry (1987):
10.1016/S0031-9422(00)81755-0
- Pinto, M.M.; Polónia, J.. "Synthesis of New Xanthones, I". Helvetica Chimica Acta 57 8 (1974): 2613-2617. http://www.scopus.com/inward/record.url?eid=2-s2.0-0001102002&partnerID=MN8TOARS.
10.1002/hlca.19740570838
|
