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Sofia Gama graduated from Instituto Superior Técnico in Chemical Engineering in 2001 and earned his PhD from the same institution in 2008 under the supervision of Prof M Amelia Santos with the co-supervision of Prof Joao Pessoa. After a post-doctoral research at the actual Centro Ciencias Tecnológicas e Nucleares (Instituto Tecnológico e Nuclear on that time) in the group of Dr Isabel Santos (2008/2014) she moved abroad first in Germany (Friedrich Schiller University Jena, 2014/2018), then France (Université de Bourgogne, in Dijon (2018/2020) and finally Poland (University of Bialystok, 2020/2022) where she was appointed as Assistant researcher. Her interested on thermodynamic studies led her to a strong participation on International Group for the Thermodynamics of Complexes, the ISMEC Group and, since Oct 2019 she is the vice-chair of the COST Action CA18202 NECTAR - Network for Equilibria and Chemical Thermodynamics Advanced Research (NECTAR). She dedicated her career to the study of metal complexes being her more recent research dedicated to the to the understanding of metal homeostasis in different living organisms, studying the metal complexation ability of different natural compounds. In this field, in 2021 she was granted with a NCN OPUS grant (ca. 400 k€) and she is the PI of the project entitled "Tryptophan metabolites and their metal complexes as new drugs in the treatment of colorectal cancer and the regulation of the human gut microbiota" . Last November she returned to Portugal, as an Assistant Researcher in C2TN, Tecnico, ULisboa, aiming the use of her experience abroad to develop a new project on the use of bacteria´metallophores for diagnosis and treatment of infection in immunocompromised patients.
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Identificação

Identificação pessoal

Nome completo
Ana Sofia Cavalheiro Gama

Nomes de citação

  • Gama, Sofia

Identificadores de autor

Ciência ID
2C1A-2100-63BC
ORCID iD
0000-0002-9689-7435
Researcher Id
F-1726-2010
Scopus Author Id
8698037400

Endereços de correio eletrónico

  • sofia.gama@ctn.tecnico.ulisboa.pt (Profissional)

Telefones

Telefone
  • 219946229 Ext.: 6229 (Profissional)

Moradas

  • Estrada Nacional 10, Km 139.7, 2695-066, Bobadela, Loures, Portugal (Profissional)

Domínios de atuação

  • Ciências Exatas - Química - Química Analítica
  • Ciências Exatas - Química - Química Inorgânica
  • Ciências Exatas - Química

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B2) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador independente (B2) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador proficiente (C1)
Francês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Italiano Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador independente (B1)
Alemão Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2008/02/01
Concluído
 Quimica (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Agentes Quelantes com Potencial Aplicação Farmacológica. Polidenticidade e Bifuncionalidade" (TESE/DISSERTAÇÃO)
 Aprovado por unanimidade
2001/02/16
Concluído
 Engenharia Quimica - Ramo Quimica Aplicada (Licenciatura)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"n/a" (TESE/DISSERTAÇÃO)
 14
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/11/14 - Atual Investigador Auxiliar (carreira) (Investigação) Centro de Ciências e Tecnologias Nucleares, Portugal
Centro de Ciências e Tecnologias Nucleares, Portugal
2020/03/01 - 2022/11/11 Assistente de Investigação (carreira) (Investigação) Uniwersytet w Bialymstoku Instytut Chemii, Polónia
Uniwersytet w Bialymstoku, Polónia
2018/10/01 - 2019/09/30 Pós-doutorado (Investigação) Institut de Chimie Moléculaire de l'Université de Bourgogne, França
2014/11/04 - 2018/06/30 Pós-doutorado (Investigação) Friedrich Schiller Universität Jena Chemisch Geowissenschaftliche Fakultät, Alemanha
2018/06/08 - 2018/06/23 Investigador visitante (Investigação) Università degli Studi di Messina, Dipartimento di Scienze chimiche, biologiche, farmaceutiche e ambientali, Itália
2018/04/13 - 2018/04/30 Investigador visitante (Investigação) Università degli Studi di Messina, Dipartimento di Scienze chimiche, biologiche, farmaceutiche e ambientali, Itália
2016/11/06 - 2016/12/11 Investigador visitante (Investigação) Università degli Studi di Messina, Dipartimento di Scienze chimiche, biologiche, farmaceutiche e ambientali, Itália
2014/02/01 - 2014/08/31 Investigador (Investigação) Centro de Ciências e Tecnologias Nucleares, Portugal
2014/02/01 - 2014/08/31 Investigador Auxiliar Convidado (carreira) (Investigação) Centro de Ciências e Tecnologias Nucleares, Portugal
2014/06/01 - 2014/06/30 Estagiário de Investigação (Investigação) Imperial College Department of Chemistry, Reino Unido
2008/02/04 - 2014/01/31 Pós-doutorado (Investigação) Centro de Ciências e Tecnologias Nucleares, Portugal
2013/07/01 - 2013/07/31 Estagiário de Investigação (Investigação) Università degli Studi del Piemonte Orientale Amedeo Avogadro Sede di Alessandria, Itália
2005/10/01 - 2005/12/20 Estagiário de Investigação (Investigação) Debreceni Egyetem Kémiai Intézet, Hungria
2004/07/01 - 2004/08/31 Estagiário de Investigação (Investigação) Magyar Tudományos Akadémia, Hungria
2003/08/01 - 2003/10/31 Estagiário de Investigação (Investigação) Debreceni Egyetem Kémiai Intézet, Hungria
2002/11/01 - 2002/12/20 Estagiário de Investigação (Investigação) Debreceni Egyetem Kémiai Intézet, Hungria
2001/09/20 - 2001/12/20 Estagiário de Investigação (Investigação) Debreceni Egyetem Kémiai Intézet, Hungria

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2011/03/01 - 2012/02/28 Professor Associado Convidado (Docente Universitário) Instituto Piaget/ ISEIT, Instituto Universitário Santo André, Portugal
Projetos

Bolsa

Designação Financiadores
2021/10 - 2025/09 Tryptophan metabolites and their metal complexes as new drugs in the treatment of colorectal cancer and the regulation of the human gut microbiota
2020/39/B/ST4/03060
Investigador responsável
Uniwersytet w Bialymstoku, Polónia
 Narodowe Centrum Nauki
Em curso
2020/03/01 - 2024/02/20 Badania zaleznosci miedzy struktura molekularna a aktywnoscia biologiczna zwiazków pochodzenia naturalnego o potencjalnym dzialaniu konserwujacym i ich kompleksów z metalami
2018/29/B/NZ9/01997
Outra
Politechnika Bialostocka, Polónia

Uniwersytet w Bialymstoku, Polónia
Narodowe Centrum Nauki
Em curso
2019/10/02 - 2023/10/01 COST Action CA18202, NECTAR - Network for Equilibria and Chemical Thermodynamics Advanced Research
CA18202
Co-Investigador Responsável (Co-IR)
Università degli Studi di Messina, Itália
 European Cooperation in Science and Technology
Em curso
2013/06 - 2016/05 Molecular and Nano Tools for Cancer Theranostics
EXCL/QEQ-MED/0233/2012
grant.Provided by PTCRIS: 126789
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2011/03 - 2014/08 Targeting telomerase inhibition with new anti-tumoral Cu(II) complexes
grant.Provided by PTCRIS: 114139
PTDC/QUI-QUI/114139/2009
Investigador responsável
Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2010/01 - 2013/06 Radiolabeled Benzazole Derivatives for In Vivo Imaging of Amyloid Aggregation
PTDC/QUI-QUI/102049/2008
grant.Provided by PTCRIS: 102049
Bolseiro de Investigação
Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2006/10 - 2010/09 Novel Drugs to Target Bio-Receptors Aimed at Pharmacological Applications
grant.Provided by PTCRIS: 56985
Bolseiro de Investigação
Universidade de Lisboa Instituto Superior Técnico, Portugal
 Fundação para a Ciência e a Tecnologia

Projeto

Designação Financiadores
2022/11/14 - 2028/11/13 Exploring Burkholderia cepacia metallophores for diagnosis and treatment of infection in immunocompromised patients
2021.02412.CEECIND/CP1651/CT0007
10.54499/2021.02412.CEECIND/CP1651/CT0007
Investigador responsável
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018/10/01 - 2020/02/01 PLUTON - Development of a test for in situ environmental monitoring of plutonium
ANR-17-CE08-0053
Bolseiro de Pós-Doutoramento
Institut de Chimie Moléculaire de l'Université de Bourgogne, França

Institut de Physique Nucléaire d'Orsay, França

IRSN Unité Sûreté nucléaire, França

Université de Strasbourg, França

TrisKem International, França
Association nationale de la recherche technique
Concluído
2014/11/04 - 2018/06/30 Chemical Mediators in Complex Biosystems (ChemBioSys)
CRC1127
Bolseiro de Investigação
Friedrich-Schiller-Universität Jena, Alemanha

Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie eV Hans-Knöll-Institut, Alemanha

Max-Planck-Institut für chemische Ökologie, Alemanha
Deutsche Forschungsgemeinschaft
Concluído

Outro

Designação Financiadores
2017/01/01 - 2020/03/31 Metal uptake by Azotobacter vinelandii metallophores - a thermodynamic approach
34083
Investigador
Friedrich-Schiller-Universität Jena, Alemanha

Università degli Studi di Messina, Itália
Ministero dell'Istruzione dell'Università e della Ricerca

Deutscher Akademischer Austauschdienst
Concluído
Produções

Publicações

Artigo em revista
  1. Anna Barylka; Giuseppina D.G. Santonoceta; Giuseppe Gattuso; Beata Godlewska-Zylkiewicz; Carmelo Sgarlata; Demetrio Milea; Sofia Gama. "Acid-base properties of hydroxyquinolines in aqueous solution: Effect of hydroxyl group position on thermodynamic protonation parameters". Journal of Molecular Liquids (2025): https://doi.org/10.1016/j.molliq.2024.126671.
    10.1016/j.molliq.2024.126671
  2. Berto, Silvia; Blasco, Salvador; Castellino, Lorenzo; Cvetkovski, Aleksandar; De Stefano, Concetta; Gama, Sofia; Garcia-Espana, Enrique; et al. "A tutorial on potentiometric data processing. Analysis of software for optimization of protonation constants". Analytica Chimica Acta (2024): https://publons.com/wos-op/publon/67329042/.
    10.1016/J.ACA.2024.342476
  3. Barylka, Anna; Godlewska-Zylkiewicz, Beata; Milea, Demetrio; Gama, Sofia. "The accurate assessment of the chemical speciation of complex systems through multi-technique approaches". Pure and Applied Chemistry (2024): https://publons.com/wos-op/publon/68063514/.
    10.1515/PAC-2024-0206
  4. Barylka, Anna; Baginska-Krakówka, Aneta; Zuccarello, Lidia; Mancuso, Francesca; Gattuso, Giuseppe; Lando, Gabriele; Sgarlata, Carmelo; et al. Autor correspondente: Milea, Demetrio. "Protonation equilibria of the tryptophan metabolite 8-hydroxyquinoline-2-carboxylic acid (8-HQA) and its precursors: A potentiometric and calorimetric comparative study". Thermochimica Acta 730 (2023): 179615. http://dx.doi.org/10.1016/j.tca.2023.179615.
    Acesso aberto • Publicado • 10.1016/j.tca.2023.179615
  5. Rendošová, Michaela; Gyepes, Róbert; Kello, Martin; Vilková, Mária; Mudronová, Dagmar; Olejníková, Petra; Cardiano, Paola; et al. Autor correspondente: Vargová, Zuzana. "Silver(I) pyrrole- and furan-2-carboxylate complexes – From their design and characterization to antimicrobial, anticancer activity, lipophilicity and SAR". Journal of Inorganic Biochemistry 246 (2023): 112266. http://dx.doi.org/10.1016/j.jinorgbio.2023.112266.
    10.1016/j.jinorgbio.2023.112266
  6. Castellino, Lorenzo; Alladio, Eugenio; Bertinetti, Stefano; Lando, Gabriele; De Stefano, Concetta; Blasco, Salvador; García-España, Enrique; et al. Autor correspondente: Berto, Silvia. "PyES – An open-source software for the computation of solution and precipitation equilibria". Chemometrics and Intelligent Laboratory Systems 239 (2023): 104860. http://dx.doi.org/10.1016/j.chemolab.2023.104860.
    Acesso aberto • 10.1016/j.chemolab.2023.104860
  7. Nalewajko-Sieliwoniuk, Edyta; Gama, Sofia; Arciszewska, Zaneta; Bogdan, Paulina; Naumowicz, Monika; Kalinowska, Monika; Swiderski, Grzegorz; et al. Autor correspondente: Godlewska-Zylkiewicz, Beata. "Chemical speciation of caffeic and p-coumaric acids with selected lanthanides". Journal of Molecular Liquids 382 (2023): 121915. http://dx.doi.org/10.1016/j.molliq.2023.121915.
    Acesso aberto • 10.1016/j.molliq.2023.121915
  8. Arciszewska, Zaneta; Gama, Sofia; Lesniewska, Barbara; Malejko, Julita; Nalewajko-Sieliwoniuk, Edyta; Zambrzycka-Szelewa, Elzbieta; Godlewska-Zylkiewicz, Beata. Autor correspondente: Godlewska-Zylkiewicz, Beata. "The translocation pathways of rare earth elements from the environment to the food chain and their impact on human health". Process Safety and Environmental Protection 168 (2022): 205-223. http://dx.doi.org/10.1016/j.psep.2022.09.056.
    10.1016/j.psep.2022.09.056
  9. Sofia Gama. "Hydroxypyridinones in nitrogen-fixing bacterial cultures: a metal buffer for molybdenum and simulation of natural conditions". Metallomics (2022): http://dx.doi.org/10.1093/mtomcs/mfac055.
    10.1093/mtomcs/mfac055
  10. Zaneta Arciszewska; Sofia Gama; Monika Kalinowska; Grzegorz Swiderski; Renata Swislocka; Ewelina Golebiewska; Monika Naumowicz; et al. "Caffeic Acid/Eu(III) Complexes: Solution Equilibrium Studies, Structure Characterization and Biological Activity". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms23020888.
    10.3390/ijms23020888
  11. Gama, Sofia; Hermenau, Ron; Frontauria, Mariachiara; Milea, Demetrio; Sammartano, Silvio; Hertweck, Christian; Plass, Winfried. "Iron Coordination Properties of Gramibactin as Model for the New Class of Diazeniumdiolate Based Siderophores". Chemistry – A European Journal 27 8 (2021): 2724-2733. http://dx.doi.org/10.1002/chem.202003842.
    Acesso aberto • 10.1002/chem.202003842
  12. Nurchi, Valeria Marina; Cappai, Rosita; Crisponi, Guido; Sanna, Gavino; Alberti, Giancarla; Biesuz, Raffaela; Gama, Sofia. "Chelating Agents in Soil Remediation: A New Method for a Pragmatic Choice of the Right Chelator". Frontiers in Chemistry 8 (2020): http://dx.doi.org/10.3389/fchem.2020.597400.
    Acesso aberto • Publicado • 10.3389/fchem.2020.597400
  13. Nunes, Patrique; Correia, Isabel; Marques, Fernanda; Matos, António Pedro; dos Santos, Margarida M. C.; Azevedo, Cristina G.; Capelo, José-Luis; et al. "Copper Complexes with 1,10-Phenanthroline Derivatives: Underlying Factors Affecting Their Cytotoxicity". Inorganic Chemistry 59 13 (2020): 9116-9134. http://dx.doi.org/10.1021/acs.inorgchem.0c00925.
    Publicado • 10.1021/acs.inorgchem.0c00925
  14. Arena, Katia; Brancato, Giuseppe; Cacciola, Francesco; Crea, Francesco; Cataldo, Salvatore; De Stefano, Concetta; Gama, Sofia; et al. "8-Hydroxyquinoline-2-Carboxylic Acid as Possible Molybdophore: A Multi-Technique Approach to Define Its Chemical Speciation, Coordination and Sequestering Ability in Aqueous Solution". Biomolecules 10 6 (2020): 930. http://dx.doi.org/10.3390/biom10060930.
    Acesso aberto • Publicado • 10.3390/biom10060930
  15. E. Palma; H. M. Botelho; G. M. Morais; I. Rodrigues; I. C. Santos; M. P. C. Campello; P. Raposinho; et al. "Unravelling the antitumoral potential of novel bis(thiosemicarbazonato) Zn(II) complexes: structural and cellular studies". JBIC Journal of Biological Inorganic Chemistry (2018): http://dx.doi.org/10.1007/s00775-018-1629-6.
    10.1007/s00775-018-1629-6
  16. R. Hermenau; K. Ishida; S. Gama; B. Hoffmann; M. Pfeifer-Leeg; W. Plass; J. F. Mohr; et al. "Gramibactin is a bacterial siderophore with a diazeniumdiolate ligand system". Nature Chemical Biology 14 9 (2018): 841-843. http://dx.doi.org/10.1038/s41589-018-0101-9.
    10.1038/s41589-018-0101-9
  17. S. Gama; M. Frontauria; N. Ueberschaar; G. Brancato; D. Milea; S. Sammartano; W. Plass. "Thermodynamic study on 8-hydroxyquinoline-2-carboxylic acid as a chelating agent for iron found in the gut of Noctuid larvae". New Journal of Chemistry (2018): https://doi.org/10.1039/C7NJ04889K.
    10.1039/C7NJ04889K
  18. E. Palma; F. Mendes; G. R. Morais; I. Rodrigues; I. C. Santos; M. P. C. Campello; P. Raposinho; et al. "Biophysical characterization and antineoplastic activity of new bis(thiosemicarbazonato) Cu(II) complexes". J Inorg Biochem (2016):
    10.1016/j.jinorgbio.2016.11.026
  19. S. M. G. Leite; Luís M. P. Lima; S. Gama; F. Mendes; M. Orio; I. Bento; A. Paulo; R. Delgado; O. Iranzo. "Copper(II) Complexes of Phenanthroline and Histidine Containing Ligands: Synthesis, Characterization and Evaluation of their DNA Cleavage and Cytotoxic Activity". Inorganic Chemistry 55 22 (2016): 11801-11814. https://doi.org/10.1021%2Facs.inorgchem.6b01884.
    10.1021/acs.inorgchem.6b01884
  20. S. Gama; I. Rodrigues; F. Mendes; I. C. Santos; E. Gabano; B. Klejevskaja; J. Gonzalez-Garcia; et al. "Anthracene-terpyridine metal complexes as new G-quadruplex DNA binders". Journal of Inorganic Biochemistry 160 (2016): 275-286. https://doi.org/10.1016%2Fj.jinorgbio.2016.04.002.
    10.1016/j.jinorgbio.2016.04.002
  21. S.Imstepf.; V. Pierroz; P. Raposinho; M. Bauwens; M. Felber; T. Fox; A. B. Shapiro; et al. "Nuclear Targeting with an Auger Electron Emitter Potentiates the Action of a Widely Used Antineoplastic Drug". Bioconjugate Chemistry 26 12 (2015): 2397-2407. https://doi.org/10.1021%2Facs.bioconjchem.5b00466.
    10.1021/acs.bioconjchem.5b00466
  22. E. Gabano; S. Gama; F. Mendes; F. Fregonese; A. Paulo; M. Ravera. "Application of microwave-assisted heating to the synthesis of Pt(II) complexes". Inorganica Chimica Acta 437 (2015): 16-19. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939800779&partnerID=MN8TOARS.
    10.1016/j.ica.2015.07.042
  23. I. Santos; S. Gama; I. Rodrigues; F. Marques; E. Palma; I. Correia; M.F.N.N. Carvalho; et al. "New ternary bipyridine-terpyridine copper(ii) complexes as self-activating chemical nucleases". RSC Advances 4 106 (2014): 61363-61377. http://www.scopus.com/inward/record.url?eid=2-s2.0-84912051462&partnerID=MN8TOARS.
    10.1039/c4ra12085j
  24. J. M. Herrera; F. Mendes; S. Gama; I. Santos; C. Navarro Ranninger; S. Cabrera; A. G. Quiroga. "Design and biological evaluation of new platinum(II) complexes bearing ligands with DNA-targeting ability". Inorganic Chemistry 53 23 (2014): 12627-12634. http://www.scopus.com/inward/record.url?eid=2-s2.0-84914141357&partnerID=MN8TOARS.
    10.1021/ic502373n
  25. E. Gabano; S. Gama; F. Mendes; M. B. Gariboldi; E. Monti; S. Bombard; S. Bianco; M. Ravera. "Study of the synthesis, antiproliferative properties, and interaction with DNA and polynucleotides of cisplatin-like Pt(II) complexes containing carcinogenic polyaromatic amines". Journal of Biological Inorganic Chemistry 18 7 (2013): 791-801. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885598920&partnerID=MN8TOARS.
    10.1007/s00775-013-1022-4
  26. S. Gama; F. Mendes; T. Esteves; F. Marques; A. Matos; J. Rino; J. Coimbra; et al. "Synthesis and Biological Studies of Pyrazolyl-Diamine PtII Complexes Containing Polyaromatic DNA-Binding Groups". ChemBioChem 13 16 (2012): 2352-2362. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868093608&partnerID=MN8TOARS.
    10.1002/cbic.201200472
  27. C. Francisco; S. Gama; F. Mendes; F. Marques; I. C. Santos; A. Paulo; I. Santos; et al. "Pt(ii) complexes with bidentate and tridentate pyrazolyl-containing chelators: Synthesis, structural characterization and biological studies". Dalton Transactions 40 21 (2011): 5781-5792. http://www.scopus.com/inward/record.url?eid=2-s2.0-79957530790&partnerID=MN8TOARS.
    10.1039/c0dt01785j
  28. S. Gama; F. Mendes; F. Marques; I. C. Santos; M. F. Carvalho; I. Correia; J. Costa Pessoa; I. Santos; A. Paulo. "Copper(II) complexes with tridentate pyrazole-based ligands: Synthesis, characterization, DNA cleavage activity and cytotoxicity". Journal of Inorganic Biochemistry 105 5 (2011): 637-644. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953066808&partnerID=MN8TOARS.
    10.1016/j.jinorgbio.2011.01.013
  29. T. Esteves; C. Xavier; S. Gama; F. Mendes; P. Raposinho; F. Marques; A. Paulo; et al. "Tricarbonyl M(I) (M = Re, 99mTc) complexes bearing acridine fluorophores: Synthesis, characterization, DNA interaction studies and nuclear targeting". Organic and Biomolecular Chemistry 8 18 (2010): 4104-4116. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955948795&partnerID=MN8TOARS.
    10.1039/c0ob00073f
  30. S. Gama; P. Dron; S. Chaves; E. Farkas; M. A. Santos. "A bis(3-hydroxy-4-pyridinone)-EDTA derivative as a strong chelator for M3+ hard metal ions: Complexation ability and selectivity". Dalton Transactions 31 (2009): 6141-6150. http://www.scopus.com/inward/record.url?eid=2-s2.0-68149122263&partnerID=MN8TOARS.
    10.1039/b904950a
  31. N. Butenko; A. I. Tomaz; O. Nouri; E. Escribano; V. Moreno; S. Gama; V. Ribeiro; et al. "DNA cleavage activity of VIVO(acac)2 and derivatives". Journal of Inorganic Biochemistry 103 4 (2009): 622-632. http://www.scopus.com/inward/record.url?eid=2-s2.0-62349111293&partnerID=MN8TOARS.
    10.1016/j.jinorgbio.2009.01.003
  32. S. Gama; M. Gil; L. Gano; E. Farkas; M. A. Santos. "Combined chelation of bi-functional bis-hydroxypiridinone and mono-hydroxypiridinone: Synthesis, solution and in vivo evaluation". Journal of Inorganic Biochemistry 103 2 (2009): 288-298. http://www.scopus.com/inward/record.url?eid=2-s2.0-58149498315&partnerID=MN8TOARS.
    10.1016/j.jinorgbio.2008.10.020
  33. M. A. Santos; S. Gama; M. Gil; L. Gano. "A new approach for potential combined chelation therapy using mono- and bis-hydroxypyridinones". Hemoglobin 32 1-2 (2008): 147-156. http://www.scopus.com/inward/record.url?eid=2-s2.0-39349108152&partnerID=MN8TOARS.
    10.1080/03630260701726939
  34. M. A. Santos; S. Gama; J. Costa Pessoa; M. C. Oliveira; I. Tóth; E. Farkas. "Complexation of molybdenum(VI) with bis(3-hydroxy-4-pyridinone)amino acid derivatives". European Journal of Inorganic Chemistry 12 (2007): 1728-1737. http://www.scopus.com/inward/record.url?eid=2-s2.0-34250858283&partnerID=MN8TOARS.
    10.1002/ejic.200601088
  35. M. A. Santos; S. Gama; L. Gano; E. Farkas. "Bis(3-hydroxy-4-pyridinone)-EDTA derivative as a potential therapeutic Al-chelating agent. Synthesis, solution studies and biological assays". Journal of Inorganic Biochemistry 99 9 SPEC. IS (2005): 1845-1852. http://www.scopus.com/inward/record.url?eid=2-s2.0-24344487413&partnerID=MN8TOARS.
    10.1016/j.jinorgbio.2005.06.022
  36. M. A. Santos; S. Gama; L. Gano; G. Cantinho; E. Farkas. "A new bis(3-hydroxy-4-pyridinone)-IDA derivative as a potential therapeutic chelating agent. Synthesis, metal-complexation and biological assays". Dalton Transactions 21 (2004): 3772-3781. http://www.scopus.com/inward/record.url?eid=2-s2.0-9644260383&partnerID=MN8TOARS.
    10.1039/b409357g
  37. M. A. Santos; R. Grazina; P. Buglyó.; S. Gama; E. Farkas. "A new bipodal carboxy-bis(hydroxypyridinonate) ligand. Synthesis and complexation with copper(II), nickel(II) and zinc(II) in aqueous solution". Polyhedron 21 25-26 (2002): 2609-2616. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036892264&partnerID=MN8TOARS.
  38. E. Farkas; H. Csóka; S. Gama; M. A. Santos. "Dihydroxamate based siderophore model, piperazine-1,4-bis-(N-methyl-acetohydroxamic acid (PIPDMAHA), as a chelating agent of molybdenum(VI)". Talanta 57 5 (2002): 935-943. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037014674&partnerID=MN8TOARS.
    10.1016/S0039-9140(02)00135-2
Livro
  1. Gama, Sofia; Kozlevcar, Bojan; Lukšic, Miha; Milea, Demetrio; Perdih, Franc; Šarac, Bojan. Book of Abstracts of the 3rd European NECTAR Conference. Ljubljana, Sérvia: University of Ljubljana, Faculty of Chemistry and Chemical Technology. 2022.
    Publicado
  2. Gama, Sofia; Milea, Demetrio. Acta of the International Symposia on Thermodynamics of Metal Complexes. Bialystok, Polónia: ISMEC GROUP SERIES. 2021.
    Publicado • Editor
Poster em conferência
  1. I. Ryza; C. Granata; Ribeiro, Nádia; E. Nalewajko-Sieliwoniuk; B. Godlewska-Zylkiewicz; S. Cabo Verde; Milea, Demetrio; Gama, Sofia. "“Chemical speciation as base for the evaluation of 8-hqa and its Ga3+ metal complexes action on microbiota radiation related resistance”". Trabalho apresentado em XIX Annual CICS-UBI Symposium, 2024.
  2. Bogdan, Paulina; Gama, Sofia; Milea, Demetrio; Nalewajko-Sieliwoniuk, Edyta; Godlewska-Zylkiewicz, Beata. Autor correspondente: Nalewajko-Sieliwoniuk, Edyta. "Solution equilibrium studies of the interaction of p-coumaric acid with lanthanides". Trabalho apresentado em International Symposium of Metal Complexes (ISMEC 2022), June 5th-8th, Valencia, Spain, 2022.
  3. Gama, Sofia; Barylka, Anna; Bukrym, Rafal; Ryza, Izabela; Bretti, Clemente; Lando, Gabriele; Akintola, Olaseun; et al. Autor correspondente: Gama, Sofia. "The Irving-Williams series and 8-hydroxyquinaldic acid (8-HQA): a thermodynamic study of 8-HQA interaction towards Mn2+, Fe2+, Co2+, Ni2+, Cu2+ and Zn2+". Trabalho apresentado em International Symposium of Metal Complexes (ISMEC 2022), June 5th-8th, Valencia (Spain), 2022.
  4. Barylka, Anna; Baginska-Krakówka, Aneta; Godlewska-Zylkiewicz, Beata; Milea, Demetrio; Gama, Sofia. Autor correspondente: Barylka, Anna. "Thermodynamic protonation parameters of a tryptophan metabolite (8-hydroxyquinoline-2-carboxilic acid) and its molecular precursors: a potentiometric study at different temperatures". Trabalho apresentado em International Symposium of Metal Complexes (ISMEC 2022), June 5th-8th, Valencia (Spain), 2022.
  5. Bretti, Clemente; Cardiano, Paola; De Stefano, Concetta; Di Pietro, Roberto; Gama, Sofia; Lando, Gabriele; Milea, Demetrio. Autor correspondente: Bretti, Clemente. "Modelling the solubility and the acid-base properties of Cinchomeronic acid in aqueous media and binding ability towards Cu2+ and Co2+". Trabalho apresentado em 2nd NECTAR European Conference, August 25th-27th, Lisboa, Portugal, 2021.
  6. Arciszewska, Zaneta; Milea, Demetrio; Gama, Sofia; Godlewska-Zylkiewicz, Beata. Autor correspondente: Arciszewska, Zaneta. "Kompleksy Wybranych Ln(III) z Naturalnymi Kwasami Fenolowymi – Specjacja w Roztworach Wodnych". Trabalho apresentado em Nauka i przemysl – metody spektroskopowe w praktyce, nowe wyzwania i mozliwosci, July 29th-30th, Lublin, Poland, 2021.
  7. Gama, Sofia; Bukrym, Rafal; Ryza, Izabela; Barylka, Anna; Bretti, Clemente; Lando, Gabriele; Brancato, Giuseppe; et al. Autor correspondente: Gama, Sofia. "Multi-technique approach applied on the study of the coordination properties of 8-hydroxyquinoline-2-carboxylic acid towards divalent metal cations". Trabalho apresentado em International Symposium on Thermodynamics of Metal Complexes (ISMEC 2021), June 16th-18th, Bialystok (Poland), 2021.
  8. Bretti, Clemente; De Stefano, Concetta; Gama, Sofia; Milea, Demetrio. Autor correspondente: Bretti, Clemente. "Acid-base properties and binding ability of creatinine towards biologically relevant metal cations in aqueous solution". Trabalho apresentado em International Symposium on Thermodynamics of Metal Complexes (ISMEC 2021), June 16th-18th, Bialystok (Poland), 2021.
  9. Arciszewska, Zaneta; Vaugon, Elodie; Milea, Demetrio; Gama, Sofia; Godlewska-Zylkiewicz, Beata. Autor correspondente: Arciszewska, Zaneta. "Caffeic acid coordination properties towards Eu(III) and Dy(III): a chemical speciation study in aqueous solution". Trabalho apresentado em International Symposium on Thermodynamics of Metal Complexes (ISMEC 2021), June 16th-18th, Bialystok (Poland), 2021.
  10. Gama, Sofia; Godlewska-Zylkiewicz, Beata; Meyer, Michel; Milea, Demetrio; Plass, Winfried. "Accurate assessment of the chemical speciation of complex systems: the use of multi-technique approaches". 2020.
  11. I. Correia; P. Nunes; S. Gama; C. P. Matos; N. Ribeiro; F. Marques; J. Costa Pessoa. "Speciation and cytotoxicity of phenanthroline metal complexes". Trabalho apresentado em 12th IBCC, 2018.
  12. S. Gama; R. Hermenau; M. Frontauria; D. Milea; S. Sammartano; C. Hertweck; W. Plass. "Iron coordination properties of Gramibactin, a novel bacterial siderophore". Trabalho apresentado em ISMEC2018, 2018.
  13. S. Gama; M. Frontauria; J. F. Mohr; T. Wichard; D. Milea; W. Boland; W. Plass. "8-Hydroxyquinoline-2-carboxylic acid and the iron metabolism on the gut of Spodoptera littoralis: A thermodynamic approach". Trabalho apresentado em ISMEC2017, 2017.
  14. J. F. Mohr; T. Wichard; W. Plass; S. Gama. "Development of metal ion buffers to control bacterial growth". Trabalho apresentado em ANAKON2017, 2017.
  15. S. Gama; M. Hilger; W. Plass. "Metallophores as Mediators for Metal Cycling: L-a-amino-acid residue ligands as new Molybdenum Buffers". Trabalho apresentado em ISMEC2016, 2016.
  16. A. Paulo; E. Palma; I. Rodrigues; G. M. Morais; M. P. C. Campello; P. Raposinho; F. Mendes; et al. "Biophysical Characterization and Antineoplastic Activity of New Bis(thiosemicarbazonato) Copper(II)". Trabalho apresentado em 3nd International Symposium on Functional Metal Complexes that Bind to Biomolecules, 4th Whole Action Meeting of the COST Action CM1105, 2016.
  17. S. Gama; J. F. Mohr; T. Wichard; W. Plass. "Hydroxypiridinone as New Molybdenum Ion Buffers". Trabalho apresentado em ISMEC2015, 2015.
  18. I. Rodrigues; F. Mendes; E. Palma; I. Correia; F. Carvalho; I. C. Santos; F. Marques; et al. "New Mixed-Ligand Cu(II) Complexes Acting as “Self-activating” Chemical Nucleases". Trabalho apresentado em EUROBIC12, 2014.
  19. A. Paulo; I. Rodrigues; M. P. C. Campello; G. Morais; I. C. Santos; V. Ferreira; F. Mendes; et al. "DNA Binding and Cytotoxic Activity of Zn(II) and Cu(II) Complexes with New Bis(thiosemicarbazone) Derivatives". Trabalho apresentado em EUROBIC12, 2014.
  20. E. Gabano; S. Gama; T. Esteves; F. Mendes; F. Marques; I. Santos; J. Coimbra; et al. "Bidentate and tridentate pyrazolyl-containing Pt(II) complexes: synthesis, characterization and in vitro evaluation". Trabalho apresentado em XII Workshop on Pharmaco-Bio-Metallics (Biomet 12), 2012.
  21. S. Gama; T. Esteves; F. Mendes; F. Marques; I. Santos; J. Coimbra; A. Matos; et al. "Pyrazolyl-diamine Pt(II) complexes bearing DNA-intercalating moieties: Synthesis, characterization and in vitro evaluation". Trabalho apresentado em ISMEC2012, 2012.
  22. M. Ravera; C. Francisco; S. Gama; F. Mendes; F. Marques; I. C. Santos; A. Paulo; et al. "Synthesis, Structural Studies and In Vitro Antiproliferative Activity of a Series of Pt(II) Complexes with Bidentate and Tridentate Pyrazolyl Derivatives". Trabalho apresentado em XXXVIII National Congress of the Inorganic Chemistry Division (Italian Chemical Society), 2010.
  23. C. Francisco; S. Gama; F. Mendes; F. Marques; A. Paulo; I. C. Santos; I. Santos; et al. "New Pt(II) Complexes with Bidentate and Tridentate Pyrazolyl-containing Chelators: Synthesis, Structural Studies and In Vitro Antitumor Activity". Trabalho apresentado em EUROBIC10, 2010.
  24. S. Gama; F. Mendes; F. Marques; I. C. Santos; I. Correia; J. Costa Pessoa; I. Santos; A. Paulo. "Synthesis, Characterization, DNA Cleavage Activity and Cytotoxicity of Copper(II) Complexes Anchored by Tridentate Pyrazol-based Ligands". Trabalho apresentado em EUROBIC10, 2010.
  25. T. Esteves; S. Gama; F. Mendes; F. Marques; A. Paulo; J. Costa Pessoa; J. Rino; C. Smith; I. Santos. "New (99mTc(CO)3)+-labeled Bombesin Conjugates Bearing an Acridine Orange Moiety for Diagnosis and/or Therapy of Cancer". Trabalho apresentado em EPI XII- Iberian Peptide Meeting, 2010.
  26. T. Esteves; S. Gama; F. Mendes; F. Marques; A. Paulo; J. Costa Pessoa; J. Rino; I. Santos. "Rhenium Tricarbonyl Complexes Bearing an Acridine Orange Moiety - Synthesis and DNA Interaction Studies". Trabalho apresentado em ISABC 10, 2009.
  27. A. Paulo; C. Francisco; S. Gama; F. Marques; I. Santos; M. Ravera; E. Gabano; D. Osella. "Platinum(II) Complexes with Pyrazolyl-Diamine Chelators Bearing DNA-Binding Groups". Trabalho apresentado em COST Action D-39, 2009.
  28. S. Gama; F. Marques; I. C. Santos; I. Correia; J. Costa Pessoa; I. Santos; A. Paulo. "Copper(II) Complexes of Pyrazole-salen Ligands - Synthesis, Characterization, DNA-Binding Properties and citotoxicity". Trabalho apresentado em FIGIPAS 10th, 2009.
  29. T. Esteves; C. Xavier; S. Gama; F. Marques; A. Paulo; G. Martins; J. Costa Pessoa; G. Viola; I. Santos. "Tricarbonyl Complexes Containing Acridine Fluorophores for Multimodal Imaging". Trabalho apresentado em World Molecular Imaging Congress, 2008.
  30. I. Cavaco; O. Nouri; V. Ribeiro; E. Escribano; V. Moreno; S. Gama; A. I. Tomaz; J. Costa Pessoa. "DNA Cleavage Activity of VO(acac)2 and Derivatives". Trabalho apresentado em 6th International Vanadium Symposium, 2008.
  31. S. Gama; M. Gil; L. Gano; E. Farkas; M. A. Santos. "Coadjuvation of a Bis(3-Hydroxy-4-pyridinone) with a Defriprone Derivative - A New Approach for Chelation Therapy". Trabalho apresentado em 9th International Symposium on Metal Ions in Biology and Medicine, 2006.
  32. M. A. Santos; S. Gama; L. Gano; E. Farkas. "Bis(3-Hydroxy-4-pyridinone) Ligands as Potential Al-Decorporating Agents. Speciation and Biodistribution Studies". Trabalho apresentado em 6th Keele Meeting on Aluminium, 2005.
  33. M. A. Santos; S. Gama; J. Costa Pessoa; E. Farkas. "Complexation studies of Bis(3-hydroxy-4-pyridinones) with Molybdenum(VI)". Trabalho apresentado em 7th International Symposium on Chelating Agents in Biomedicine, Toxicology and Therapeutics, 2004.
  34. M. A. Santos; S. Gama; L. Gano; E. Farkas. "Bis-(3-hydroxy-4-pyridinone) Derivatives as Potential Al-Decorporating Agents.-Speciation and Biodistribution Studies". Trabalho apresentado em 8th International Symposium on Metal Ions in Biology and Medicine, 2004.
  35. S. Gama; J. Costa Pessoa; E. Farkas; M. A. Santos. "A New Bis(3-Hydroxy-4-pyridinonate)-EDTA Derivative as a Chelator for Metal Ions". Trabalho apresentado em 28th International Conference on Solution Chemistry,, 2003.
  36. S. Gama; L. Gano; M. A. Santos. "A New Bis(3-Hydroxy-4-pyridinonate)-EDTA Derivative - Synthesis, Physicochemical Properties and 67Ga Biodistribution". Trabalho apresentado em 5º Encontro Nacional de Química Orgânica, 2003.
    10.1063/1.4872898
  37. S. Gama; R. Grazina; J. Costa Pessoa; E. Farkas; M. A. Santos. "A New Tetradentate 3-Hydroxy-4-pyridinone Ligand as Chelator for Divalent and Trivalent Metal Ions". Trabalho apresentado em 6th European Conference on Biological Inorganic Chemistry, 2002.
  38. J. Costa Pessoa; M. J. Calhorda; V. Felix; S. Gama; I. Correia; M. T. Duarte; S. Marcao; M. F. M. Piedade; A. I. Tomaz. "N-salicylideneamino acidate complexes of oxovanadium(IV) - Stability of the CL and AL diastereomers in solution". Trabalho apresentado em ICBIC10, 2001.
Resumo em conferência
  1. Nádia Ribeiro; Gama, Sofia; Cabo Verde, Sandra; Gonzalo Restrepo-Guerrero. "Study of the action of a tryptophan metabolite, 8-hydroxyquinoline-2-carboxylic acid, and its Ga(III) complex on microbiota exposed to ionizing radiation.". Trabalho apresentado em 15th National Organic Chemistry Meeting & 8th National Medicinal Chemistry Meeting, Faro, 2024.
    Publicado

Propriedade Intelectual

Patente
  1. M. A. Santos; R. Grazina; L. Gano; S. Gama. 2001. "Novos Agentes Quelantes Polidentados do tipo 3-Hidroxi-4-piridinona". Portugal.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/11/13 “Chemical speciation modelling: the first step for the design of better radiopharmaceuticals”, CICS-UBI “Lunch Seminar”
Centro de Investigação em Ciências da Saúde (CICS), Universidade da Beira Interior (UBI) (Covilha, Portugal)
2024/09/11 “Modeling the dependence of stability constants on medium and ionic strength. The pure water model” 21st IUPAC International Symposium on Solubility Phenomena and Related Equilibrium Processes (ISSP21)
University of Novi Sad (Novi Sad, Sérvia)
2024/08/26 “Unravelling the binding features for the recognition equilibria of quercetin and its zinc(II)-complex into a macrocyclic-based micellar aggregate” XXVIII Congresso Nazionale della Società Chimica Italiana
Società Chimica Italiana (Milano, Itália)
2024/06/28 “The “Pure Water” Model, a New/Old Approach for the Medium and Ionic Strength Dependence of Formation Constants” 5th International Congress of Chemists and Chemical Engineers of Bosnia and Herzegovina
University of Sarajevo-Faculty of Science (Sarajevo, Bósnia-Herzegovina)
2024/06/10 “PyES and libeq, tools for a unified framework for equilibrium data treatment” – L. Castellino, E. Alladio, S. Bertinetti, S. Gama, E. García-España, S. Blasco, G. Lando, C. De Stefano, D. Milea, S. Berto, ISMEC2024, June 10-13, Nice, France, 2024. International Symposium on Thermodynamics of Metal Complexes (ISMEC 2024)
Université Côte d'Azur (Nice, França)
2024/02/26 “SpectrApp and PyES, two free tools for soft and hard modelling of chemical systems” 4th European NECTAR Conference and Final Action Meeting
University of Messina (Milazzo, Itália)
2024/02/26 “Scandium(III) hydrolysis and complexation studies with desferrioxamine B” 4th European NECTAR Conference and Final Action Meeting
University of Messina (Milazzo, Itália)
2024/02/26 “The accurate assessment of the chemical speciation of complex systems: a multi-technique approach” 4th European NECTAR Conference and Final Action Meeting
University of Messina (Milazzo, Itália)
2024/02/10 Speciation and redox-properties study of n-hydroxycoumarins complexes with copper(II) and vanadium(IV/V) metal ions” International Symposium on Thermodynamics of Metal Complexes (ISMEC 2024)
Université Côte d'Azur (Nice, França)
2024/01/22 “Study of the action of a tryptophan metabolite, 8-hydroxyquinoline-2-carboxylic acid, and its Ga(III) complex on microbiota exposed to ionizing radiation” 15th National Organic Chemistry Meeting and 8th National Medicinal Chemistry Meeting
Universidade do Algarve (Faro, Portugal)
2023/09/21 "Current it tools and best practices for determination of stability constants from potentiometric data" XXX Congresso della Divisione di Chimica Analitica della Società Chimica Italiana, September 17th-21st, Vasto, Italy
(Vasto, Itália)
2023/09/21 "Multi-technique characterization and speciation of oxovanadium(IV)/8-hydroxyquinoline-2-carboxylic acid aqueous system" XXX Congresso della Divisione di Chimica Analitica della Società Chimica Italiana, September 17th-21st, Vasto, Italy
(Vasto, Itália)
2023/07/13 "Chelators and (Radio)metals: Speciation and Thermodynamic Studies" 38th International Conference on Solution Chemistry (38ICSC)
University of Ljubljana, Slovenia and University of Novi Sad, Serbia (Belgrade, Sérvia)
2023/06/12 "Notes and advancements in the development of PyES, an open-source software for the simulation of thermodynamic equilibria in soluble and precipitable systems" International Symposium of Metal Complexes (ISMEC 2023), June 11th-14th, Urbino, Italy
(Urbino, Itália)
2023/06/12 "Multi-techniques characterization and speciation of oxovanadium(IV)/8-hydroxyquinoline-2-carboxylic acid aqueous system" International Symposium of Metal Complexes (ISMEC 2023), June 11th-14th, Urbino, Italy
(Urbino, Itália)
2023/03/21 "Chemical speciation modelling as a first step towards the design of efficient radiopharmaceuticals" ChemForum (Centro de Química Estrutural (CQE) Seminars)
Instituto Superior Tecnico, Universidade de Lisboa (Lisboa, Portugal)
2022/09/15 "PYES – an open source software for the computation of in solution and precipitation equilibria" XXIX Congresso della Divisione di Chimica Analitica della Società Chimica Italiana, September 11th-15th, Messina,Italy
(Messina, Itália)
2022/08/25 "Comparative study on the current tools for optimization of stability constants from potentiometric data" 3th NECTAR European Conference, August 24th-26th, Ljubljana, Slovenia
(Ljubliana, Eslovénia)
2022/08/25 "Open-source software for species concentration calculation and potentiometric data analysis" 2nd NECTAR European Conference, August 25th-27th, Lisboa, Portugal
(Lisboa, Portugal)
2021/08/26 "Complexation of Th(IV) and U(VI) with a new tetrahydroxamic acid by affinity capillary electrophoresis" 2nd NECTAR European Conference, August 25th-27th, Lisboa, Portugal
(Lisboa, Portugal)
2021/03/25 "State of art and advances on the definition of Fe3+ hydrolysis" NECTAR Spring Web-Meeting, online, March 25th-26th, 2021
(Faro, Portugal)
2021/03/25 "An open-source software for potentiometric data analysis" NECTAR Spring Web-Meeting, online, March 25th-26th, 2021
(Faro, Portugal)
2019/06/17 "Coordination chemistry: An overview of the role of metal complexes in biology and medicine" Institut of Chemistry Seminars
Institut of Chemistry, Faculty of Biology and Chemistry, University of Bialystok (Bialystok, Polónia)
2019/06/12 "DFO-PIPO: An optimized ligand for tetravalent cations" International Symposium of Metal Complexes (ISMEC 2019), June 11th-14th, Debrecen (Hungary)
University of Debrecen (Debrecen, Hungria)
2019/06/12 "Interactions of 8-hydroxyquinoline-2-carboxylic acid with molybdate in aqueous solution" International Symposium of Metal Complexes (ISMEC 2019), June 11th-14th, Debrecen (Hungary)
(Debrecen, Hungria)
2019/01/22 "The use of multi-technique approaches for the accurate assessment of the chemical speciation of complex systems" Advanced Workshop on Solution Chemistry of TCE´s
University of Bialystok, Faculty of Biology and Chemistry, Institute of Chemistry (Bialystok, Polónia)
2019/01/22 "Survey on the criteria adopted for the quantification of the sequestering ability of ligands towards metal cations" Advanced Workshop on Solution Chemistry of TCE´s
University of Bialystok, Faculty of Biology and Chemistry, Institute of Chemistry (Bialystok, Polónia)
2018/04/22 "Metal uptake by natural metallophores: a thermodynamic approach" CHIBIOFARAM Seminars
Dipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali (CHIBIOFARAM), Università degli Studi di Messina (Messina, Itália)
2018/02/26 "Metal complexes in biology and medicine: a brief overview" ICMUB seminars
Institut de Chimie Moléculaire de l'Université de Bourgogne (ICMUB) (Dijon, França)
2018/02/23 "Metal Complexes in Biology and Medicine: A Brief Overview" CHIMIE seminars
Institut de Chimie de Strasbourg (CHIMIE) (Strasbourg, França)
2017/09/11 Bifunctional triamine Pt(II) complexes containing a DNA intercalating moiety XXVI Congresso Nazionale della Società Chimica Italiana
Società Chimica Italiana (Paestum, Itália)
2017/09/11 "Survey on the criteria adopted for the quantification of the sequestering ability of ligands towards metal cations" XXVI Congresso Nazionale della Società Chimica Italiana, Sep 10th-14th, Paestum (SA), Italy
(Paestum, Itália)
2017/08/29 "Metal complexes in biology and medicine: a brief overview" 3rd Summer School Of Bioinorganic Medicinal Chemistry
Dipartimento di Scienze Chimiche e Geologiche, Universtità di Cagliari (Cagliari, Itália)
2017/07/04 "A. Vinelandii catecholates as molybdophores: Mo(VI) sequestration by Protochelin in aqueous solution" 4th EuCheMS Inorganic Chemistry Conference (EICC-4)
(Copenhaga, Dinamarca)
2016/04/28 "Anthracene-Terpyridine Metal complexes as new G-Quadruplex DNA binders" 3rd International Symposium on Functional Metal Complexes that Bind to Biomolecules, 4th Whole Action Meeting of the COST Action CM1105
(Palma de Maiorca, Espanha)
2014/08/22 "G-Quadruplex DNA Interactions of Anthracene-Terpyridine M(II) (M = Pt, Cu) Complexes" 3rd Whole Action Meeting of the COST Action CM1105
(Zurique, Suiça)
2014/08/22 "Zn(II) and Cu(II) Complexes with New Bis(thiosemicarbazone) Derivatives: Preliminary Evaluation of Cytotoxicity and G-quadruplex Binding" 2nd International Symposium on Functional Metal Complexes that Bind to Biomolecules, 3rd Whole Action Meeting of the COST Action CM1105
Department of Chemistry, University of Zurich (UZH) (Zurique, Suiça)
2014/04/11 "Artificial Nucleases Based on New Bipyridine-Terpyridine Cu(II) Complexes" 10th Inorganic Chemistry Conference
Sociedade Portuguesa de Química (Costa da Caparica, Portugal)
2013/09/09 "Anticancer Copper(II) and Platinum(II) Complexes with Anthracene-Containing Terpyridine Ligands" 2nd Whole Action Meeting of the COST Action CM1105, Sep. 9th-10th, Barcelona, Spain
(Barcelona, Espanha)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2023/11/02 - Atual Speciation models for the recovery of critical elements from aqueous matrices
Coorientador de Claudia Granata
 Dottorato in Scienze Chimiche (Doutoramento)
Università degli Studi di Messina, Itália
2021/10/01 - Atual "Study of the complexation ability of tryptophan derivatives with metal ions and evaluation of their antimicrobial and antiproliferative activity as potential anticancer drugs" ("Badanie zdolnosci kompleksowania pochodnych tryptofanu jonami metali i ocena ich aktywnosci przeciwdrobnoustrojowej i antyproliferacyjnej jako potencjalnych leków przeciwnowotworowych")
Coorientador de Anna Barylka
 Chemistry (Doutoramento)
Uniwersytet w Bialymstoku, Polónia
2022/09/01 - 2023/06/29 "Study of the coordination behavior of 8-hydroxyquinoline-2-carboxilix acid (8-HQA) towards Ga(III) ions in aqueous solution"
Coorientador de Izabela Ryza
 Analytical Chemistry (Mestrado)
Uniwersytet w Bialymstoku, Polónia
2021/09/01 - 2022/06/30 "Badanie specjacji kompleksów kwasu p-kumarowego z jonami Gd(III), Dy(III) i Eu(III)” (Chemical speciation study of of p-coumaric acid metal complexes with Gd (III), Dy (III) and Eu (III)).
Coorientador de Paulina Bogdan
 Analytical Chemistry (Mestrado)
Uniwersytet w Bialymstoku, Polónia
2021/09/01 - 2022/06/30 "Badanie specjacji chemicznej pochodnych tryptofanu w roztworach wodnych” (Study of the chemical speciation of tryptophan derivatives in aqueous solution).
Coorientador de Aneta Baginska
 Analytical Chemistry (Mestrado)
Uniwersytet w Bialymstoku, Polónia
2020/09/01 - 2021/06/30 "Badanie skladu kompleksów kwasu p-kumarowego z lantanowcami” (Study of the chemical speciation of p-coumaric acid complexes with lanthanides).
Coorientador de Natalia Jutkiewicz
Analytical chemistry (Mestrado)
Uniwersytet w Bialymstoku, Polónia
2020/09/01 - 2021/06/30 "Badanie skladu kompleksów kwasu p-kumarowego z metalami istotnymi fizjologicznie” (Study of the chemical speciation of p-coumaric acid complexes with physiologically relevant metal ions)
Coorientador de Maksymilian Kowalewski
Analytical Chemistry (Mestrado)
Uniwersytet w Bialymstoku, Polónia
2020/09/01 - 2021/06/30 "Badanie reakcji kompleksowania kwasu 8-hydroksychinolino-2-karboksylowego jonami kobaltu (II) i manganu(II)” (Study of 8-hydroxyquinoline-2-carboxylic acid interaction towards cobalt (II) and manganese (II))
Coorientador de Rafal Bukrym
Analytical Chemistry (Mestrado)
Uniwersytet w Bialymstoku, Polónia
2020/09/01 - 2021/06/20 " Chemical thermodynamic study of Zn(II) complexes of 8-HQA, a metallophore recognized as metalloenzyme inhibitor with potential therapeutic properties”
Coorientador
 Analytical Chemistry (Licenciatura/Bacharelato)
Uniwersytet w Bialymstoku, Polónia
2017/07/01 - 2018/03/31 Azotobacter vinelandii catecholates as metallophores: Mo(VI) and Fe(III) sequestration in aqueous solution
Orientador de Mariachiara Frontauria
Friedrich Schiller Universität Jena Chemisch Geowissenschaftliche Fakultät, Alemanha
2017/03/01 - 2017/10/28 Cyclodextrin inclusion compounds of Mo(VI) and V(V) complexes
Orientador de Daniela Winkel
 Chemistry Bachelor (Licenciatura/Bacharelato)
Friedrich Schiller Universität Jena Chemisch Geowissenschaftliche Fakultät, Alemanha
2017/01/02 - 2017/04/30 Speciation of metal ions in metallophore systems
Orientador de Mariachiara Frontauria
 ERASMUS+ program (Iniciação científica)
Friedrich Schiller Universität Jena Chemisch Geowissenschaftliche Fakultät, Alemanha
2015/03 - 2015/09 L-a-Aminosäure-Derivate als neue Molybdän-Puffer”
Orientador de Markus Hilger
 Chemistry Bachelor (Licenciatura/Bacharelato)
Friedrich Schiller Universität Jena Chemisch Geowissenschaftliche Fakultät, Alemanha
2013/06/01 - 2014/08/31 Targeting telomerase inhibition with new anti-tumoral Cu(II) complexes
Orientador de Francisco Silva
Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
2012/09/01 - 2014/08/31 Targeting telomerase inhibition with new anti-tumoral Cu(II) complexes
Orientador de Inês Rodrigues
Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
2011/03/01 - 2011/10/31 Targeting telomerase inhibition with new anti-tumoral Cu(II) complexes
Orientador de Teresa Esteves
Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
2009/06/01 - 2009/08/31 Multicomponent Technetium and Gallium Metallointercalators for Targeted Radiotherapy
Orientador de Marco Araujo
Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2023/04/01 - 2023/09/30 Training School: Vice-chair of the NECTAR Advanced school on aqua ions and hydrolysis-related equilibria, Zagreb (Croatia), Sep 29th, 2023. (2023/09/29 - 2023/09/29)
Outro (Membro da Comissão Científica)
 Ruder Boškovic Institute, Croácia
2023/01/07 - 2023/07/27 Training School: Vice-chair of the 3rd ISMEC - NECTAR Training School on the Determination, Analysis and Use of Thermodynamic Data: SOLvE, Advances in SOLution Equilibria, held online, July 24th-26th, 2023. (2023/07/24 - 2023/07/26)
Outro (Coorganizador)
 Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
2023/01/10 - 2023/05/30 Training School: Vice-chair of the NECTAR Training School on Communication in Science (NECTAR-SciComm), Cagliari (Italy), May 29th, 2023. (2023/05/29 - 2023/05/29)
Outro (Membro da Comissão Científica)
 Università degli Studi di Cagliari, Itália
2022/01/07 - 2022/07/28 Training School: VIce-chair of the 2st ISMEC - NECTAR Training School on the Determination, Analysis and Use of Thermodynamic Data: SOLvE, Advances in SOLution Equilibria, held online, July 25th-27th, 2022. (2022/07/25 - 2022/07/27)
Outro (Coorganizador)
 Uniwersytet w Bialymstoku, Polónia
2022/03/01 - 2022/07/27 Training School: Vice-Chair of the NECTAR Training School on Calorimetry, Ljubljana (Slovenia), July 27th, 2022. (2022/07/27 - 2022/07/27)
Outro (Membro da Comissão Científica)
 Univerza v Ljubljani, Eslovénia
2021/01/07 - 2021/07/29 Training School: VIce-chair of the 1st ISMEC - NECTAR Training School on the Determination, Analysis and Use of Thermodynamic Data: SOLvE, Advances in SOLution Equilibria, held online, July 26th-28th, 2021. (2021/07/26 - 2021/07/28)
Outro (Coorganizador)
 Uniwersytet w Bialymstoku, Polónia
2021/02/01 - 2021/06/30 International Symposium on Metal Complexes 2021 (ISMEC2021): Organizing Committee Chair of the ISMEC2021, meeting dedicated to the discussion and knowledge exchange on the most recent advances in the chemistry of metal complex formation, with prospective applications on environmental, biomedical, analytical, inorganic and physical-chemical fields. (2021/06/16 - 2021/06/18)
Conferência (Presidente da Comissão Organizadora)
 Uniwersytet w Bialymstoku, Polónia
2020/04/02 - 2020/10/10 KOSAT - KOnwersatorium Spektrometrii ATomowej (2020/09/06 - 2020/09/07)
Conferência (Membro da Comissão Organizadora)
 Uniwersytet w Bialymstoku, Polónia
2011/09 - 2012/06/22 International Symposium on Metal Complexes 2012 (ISMEC2012): meetingdedicated to the discussion and knowledge exchange on the most recent advances in the chemistry of metal complex formation, with prospective applications on environmental, biomedical, analytical, inorganic and physical-chemical fields. (2012/06/18 - 2012/06/22)
Conferência (Membro da Comissão Organizadora)
 Universidade de Lisboa Instituto Superior Técnico, Portugal
2007/09/01 - 2008/07/19 6th International Vanadium Symposium (V6): interdisciplinary event for researchers from all over the world dedicated to vanadium related research topics including coordination chemistry, catalysis, biological chemistry, vanadium based drugs, toxicology, environmental and occupational exposure, among other relevant topics. (2008/07/17 - 2008/07/19)
Conferência (Membro da Comissão Organizadora)
 Universidade de Lisboa Instituto Superior Técnico, Portugal
2006/01/02 - 2006/05/23 9th International Symposium on Metal Ions and Medicine: meeting of the world’s leading specialists to exchange information on the most recent advances in understanding metals and the part they play in treating diseases. (2006/05/19 - 2006/05/23)
Conferência (Membro da Comissão Organizadora)
 Universidade de Lisboa Instituto Superior Técnico, Portugal

Arbitragem científica em conferência

Nome da conferência Local da conferência
2024/06/10 - 2024/06/13 International Symposium on Thermodynamics of Metal Complexes (ISMEC 2024) Universite Cote d'Azur, Nice, France
2024/02/26 - 2024/02/27 4th European NECTAR Conference and Final Action Meeting University of Messina, Italy
2023/06/11 - 2023/06/14 International Symposium on Metal Complexes (ISMEC 2023) University of Urbino, Italy
2022/08/24 - 2022/08/26 3rd European NECTAR Conference University of Ljubliana, Slovenia
2022/06/05 - 2022/06/08 International Symposium of Metal Complexes (ISMEC 2022) University of Valencia, Spain
2021/08/25 - 2021/08/27 2nd European NECTAR Conference University of Lisbon, Portugal
2021/06/16 - 2021/06/18 International Symposium on Thermodynamics of Metal Complexes (ISMEC 2021) University of Bialystok, Poland
2020/03/05 - 2020/03/06 1st European NECTAR Conference University of Belgrade, Serbia

Membro de associação

Nome da associação Tipo de participação
2016/06/01 - Atual International Group of Thermodynamics of Metal Complexes

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2022/07/14 - Atual Member of the "Commissione giudicatrice per il conseguimento del titolo di dottore di ricerca in Scienze e tecnologie per Innovazione - XXXII ciclo" of the dell'Universitá degli Studi di Cagliari, Italy.
Membro
 Università degli Studi di Cagliari, Itália
2020/05/20 - Atual Member of Collegio dei Docenti del Dottorato di Ricerca in Scienze Chimiche dell'Universitá degli Studi di Messina, Italy, XXXVI e XXXVII Ciclo.
Membro
 Università degli Studi di Messina, Itália
Distinções

Prémio

2019 Granted Visiting Researcher at University of Messina
Università degli Studi di Messina, Itália

Outra distinção

2011 Specialization course: "Radiological Protection and Safety - Radiation Protection for Radiation Sources Users"
Centro de Ciências e Tecnologias Nucleares, Portugal