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Rui Vasco Portas Ferreira Simões. Concluiu a sua Licenciatura em Bioquímica em 2003/07/27 pelo(a) Universidade de Coimbra, Faculdade de Ciências e Tecnologia, e Doutoramento em Bioquímica, na área de Biofísica Celular em 2010/02/26 pela Universidade de Coimbra, Faculdade de Ciências e Tecnologia. Deu 14 palestras por convite sobre a sua investigação em eventos científicos. Publicou 30 artigos em revistas especializadas, dos quais é primeiro autor em 14 e correspondente em 10. Possui 2 livro(s) e tem 68 apresentações em congressos, das quais foi primeiro autor de 36 e orador em 21. Recebeu 18 prémios. Trabalha na área de Ciências Naturais com ênfase em Ciências Biológicas, Bioquímica e Biofísica. A sua investigação tem como objectivo a caracterização da heterogeneidade tumoral em modelos preclínicos da doença, durante a sua progressão e resposta a terapia, mediante métodos não invasivos de imagem e espectroscopia por ressonância magnética.
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Identificação

Identificação pessoal

Nome completo
Rui Vasco Portas Ferreira Simões

Nomes de citação

  • Simões, Rui V

Identificadores de autor

Ciência ID
2E17-9F8A-504C
ORCID iD
0000-0001-7574-4723

Moradas

  • Rua Alfredo Allen 208, 4200-135, Porto, Porto, Portugal (Profissional)
  • Av Comendador Ferreira de Matos 856, 1D, 4450-121, Matosinhos, Matosinhos, Portugal (Pessoal)

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências Naturais - Ciências Biológicas - Biofísica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2010/02/26
Concluído
 Bioquímica (Doutoramento)
Especialização em Especialidade: Biofísica Molecular
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Towards Molecular Imaging of Preclinical Brain Tumor Models by Mrs" (TESE/DISSERTAÇÃO)
 magna cum laude
1997/10/15 - 2003/07/27
Concluído
 Bioquímica (Licenciatura)
Especialização em Bioquímica
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Princípios básicos das técnicas NMR/MRI e optimização das condições necessárias para estudos in-vivo de ratinhos dentro de um sistema MRI de alto campo" (TESE/DISSERTAÇÃO)
 16/20
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/09/01 - Atual Assistente de Investigação (carreira) (Investigação) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/09/15 - 2022/08/31 Pós-doutorado (Investigação) Fundação Champalimaud, Portugal
Fundação Champalimaud, Portugal
2014/01/01 - 2017/07/15 Investigador (Investigação) Fundación Sant Joan de Déu, Espanha
Fetal Medicine Research Center, Espanha
2013/05/21 - 2013/12/31 Investigador (Investigação) Fundació Clínic per a la Recerca Biomédica, Espanha
Fetal Medicine Research Center, Espanha
2010/05/21 - 2013/05/10 Pós-doutorado (Investigação) Memorial Sloan Kettering Cancer Center, Estados Unidos
Memorial Sloan Kettering Cancer Center, Estados Unidos
2009/02/01 - 2010/05/01 Pós-doutorado (Investigação) Universitat Autònoma de Barcelona, Espanha
Universitat Autònoma de Barcelona, Espanha
2002/09/15 - 2003/07/15 Estagiário de Investigação (Investigação) Universidade de Coimbra, Portugal
Universitat Autònoma de Barcelona, Espanha

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2005/02/01 - 2009/01/31 Estudante de Doutoramento Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Universitat Autònoma de Barcelona, Espanha
2003/09/15 - 2005/01/31 Técnico Investigação Universitat Autònoma de Barcelona, Espanha
Universitat Autònoma de Barcelona, Espanha
Projetos

Bolsa

Designação Financiadores
2024/07/01 - 2024/12/31 Harnessing translational MRI for pancreatic tumor assessment (TRANSMAP)
PARSUK-FCT-BRF2024-TRANSMAP
Investigador responsável
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2014/05/01 - 2017/07/15 CEREBRA
CEREBRA-UB
Bolseiro de Investigação
Fetal Medicine Research Center, Espanha
 Cerebra Innovation Centre
Em curso
2009/01/01 - 2011/01/01 Phenotype and molecular imaging of brain cancer progression by MRS/MRI in murine models. Translational application to humans (PHENOIMA)
MYCT/SAF-2008-03323
Bolseiro de Doutoramento
Universitat Autònoma de Barcelona Departament de Bioquímica i Biologia Molecular, Espanha
 España Ministerio de Ciencia e Innovación
Concluído
2009/01 - 2011/01 Phenotype and molecular imaging of brain cancer progression by MRS/MRI in murine models. Translational application to humans (PHENOIMA)
MYCT/SAF-2008-03323
 España Ministerio de Ciencia e Innovación
2005/02/01 - 2009/01/31 Towards Molecular imaging of preclinical brain tumor by MRS
10316/13879
Bolseiro de Doutoramento
Universitat Autònoma de Barcelona Departament de Bioquímica i Biologia Molecular, Espanha
 Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2022/09/01 - 2028/08/31 Longitudinal assessment of tumor progression and treatment response with translational MRI
CEECINST/00131/2021/CP2805/CT0001
10.54499/CEECINST/00131/2021/CP2805/CT0001
Investigador
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2019/05/03 - 2021/05/02 CHyMERA – Monitoring cancer heterogeneity based on the dynamic assessment of the Warburg effect under metabolic perturbation
H2020-MSCA-IF-2018-CHyMERA
Bolseiro de Pós-Doutoramento
Fundação Champalimaud, Portugal
 European Commission
Concluído
2009/01/01 - 2010/01/01 Networking Biomedical Research Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN)
CB06/01/0010
Investigador
Universitat Autònoma de Barcelona Departament de Bioquímica i Biologia Molecular, Espanha
 Centro de Investigación Biomédica en Red Bioingeniería Biomateriales y Nanomedicina
Em curso
Produções

Publicações

Artigo em conferência
  1. Ortega-Martorell, S.; Lisboa, P.J.G.; Vellido, A.; Simões, R.V.; Julià-Sapé, M.; Arús, C.. "Brain tumor pathological area delimitation through Non-negative Matrix Factorization". Trabalho apresentado em IEEE International Conference on Data Mining (ICDM): Workshop on Biological Data Mining and its Applications in Healthcare (BioDM)., Vancouver, 2011.
    Publicado • 10.1109/ICDMW.2011.41
Artigo em revista
  1. Miranda, Jezid; Paules, Cristina; Noell, Guillaume; Youssef, Lina; Paternina-Caicedo, Angel; Crovetto, Francesca; Cañellas, Nicolau; et al. "Similarity network fusion to identify phenotypes of small-for-gestational-age fetuses". iScience 26 9 (2023): 107620. http://dx.doi.org/10.1016/j.isci.2023.107620.
    10.1016/j.isci.2023.107620
  2. Lina Youssef; Francesca Crovetto; Rui Vasco Simoes; Jezid Miranda; Cristina Paules; Miquel Blasco; Marta Palomo; et al. "The Interplay between Pathophysiological Pathways in Early-Onset Severe Preeclampsia Unveiled by Metabolomics". Life (2022): https://doi.org/10.3390/life12010086.
    10.3390/life12010086
  3. Simões, R.V.; Henriques, R.N.; Cardoso, B.M.; Fernandes, F.F.; Carvalho, T.; Shemesh, N.. "Glucose fluxes in glycolytic and oxidative pathways detected in vivo by deuterium magnetic resonance spectroscopy reflect proliferation in mouse glioblastoma". NeuroImage: Clinical 33 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85123426654&partnerID=MN8TOARS.
    10.1016/j.nicl.2021.102932
  4. Muñoz-Moreno, E.; Simões, R.V.; Tudela, R.; López-Gil, X.; Soria, G.. "Spatio-temporal metabolic rewiring in the brain of TgF344-AD rat model of Alzheimer’s disease". Scientific Reports 12 1 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85139463498&partnerID=MN8TOARS.
    10.1038/s41598-022-20962-6
  5. Gonçalves, S.I.; Simões, R.V.; Shemesh, N.. "Short TE downfield magnetic resonance spectroscopy in a mouse model of brain glioma". Magnetic Resonance in Medicine 88 2 (2022): 524-536. http://www.scopus.com/inward/record.url?eid=2-s2.0-85126761075&partnerID=MN8TOARS.
    10.1002/mrm.29243
  6. Bilreiro C; Fernandes FF; Andrade L; Chavarrías C; Simões RV; Matos C; Shemesh N. "Effective bowel motion reduction in mouse abdominal MRI using hyoscine butylbromide.". Magnetic resonance in medicine (2021): http://europepmc.org/abstract/med/33977522.
    10.1002/mrm.28824
  7. Youssef, L.; Simões, R.V.; Miranda, J.; García-Martín, M.L.; Paules, C.; Crovetto, F.; Amigó, N.; et al. "Paired maternal and fetal metabolomics reveal a differential fingerprint in preeclampsia versus fetal growth restriction". Scientific Reports 11 1 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85111095727&partnerID=MN8TOARS.
    10.1038/s41598-021-93936-9
  8. Simões, Rui. "Multicenter prospective clinical study to evaluate children short-term neurodevelopmental outcome in congenital heart disease (children NEURO-HEART): study protocol.". BMC pediatrics (2019): http://europepmc.org/articles/PMC6737686.
    10.1186/s12887-019-1689-y
  9. Rui V. Simões; Lubo Zhang; Miquel E. Cabañas; Carla Loreiro; Miriam Illa; Fatima Crispi; Eduard Gratacós. "Assessment of prenatal cerebral and cardiac metabolic changes in a rabbit model of fetal growth restriction based on 13C-labelled substrate infusions and ex vivo multinuclear HRMAS". PLOS ONE (2018): https://doi.org/10.1371/journal.pone.0208784.
    10.1371/journal.pone.0208784
  10. "Metabolic profiling and targeted lipidomics reveals a disturbed lipid profile in mothers and fetuses with intrauterine growth restriction". Scientific Reports (2018): http://dx.doi.org/10.1038/s41598-018-31832-5.
    10.1038/s41598-018-31832-5
  11. Simões, R.V.; Veeraperumal, S.; Serganova, I.S.; Kruchevsky, N.; Varshavsky, J.; Blasberg, R.G.; Ackerstaff, E.; Koutcher, J.A.. "Inhibition of prostate cancer proliferation by Deferiprone". NMR in Biomedicine 30 6 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85014721481&partnerID=MN8TOARS.
    10.1002/nbm.3712
  12. Simões, R.V.; Muñoz-Moreno, E.; Cruz-Lemini, M.; Eixarch, E.; Bargalló, N.; Sanz-Cortés, M.; Gratacós, E.. "Brain metabolite alterations in infants born preterm with intrauterine growth restriction: association with structural changes and neurodevelopmental outcome". American Journal of Obstetrics and Gynecology 216 1 (2017): 62.e1-62.e14. http://www.scopus.com/inward/record.url?eid=2-s2.0-85006804681&partnerID=MN8TOARS.
    10.1016/j.ajog.2016.09.089
  13. Cortes, M.S.; Bargallo, N.; Arranz, A.; Simoes, R.; Figueras, F.; Gratacos, E.. "Feasibility and Success Rate of a Fetal MRI and MR Spectroscopy Research Protocol Performed at Term Using a 3.0-Tesla Scanner". Fetal Diagnosis and Therapy 41 2 (2017): 127-135. http://www.scopus.com/inward/record.url?eid=2-s2.0-84982273106&partnerID=MN8TOARS.
    10.1159/000445947
  14. Castells Domingo, X.; Ferrer-Font, L.; Davila, M.; Candiota, A.P.; Simões, R.V.; Fernández-Coello, A.; Gabarrós, A.; et al. "Improving Ribosomal RNA Integrity in Surgically Resected Human Brain Tumor Biopsies". Biopreservation and Biobanking 14 2 (2016): 156-164. http://www.scopus.com/inward/record.url?eid=2-s2.0-84963829114&partnerID=MN8TOARS.
    10.1089/bio.2015.0086
  15. Simões, R.V.; Ortuño, J.E.; Bokacheva, L.; Candiota, A.P.; Ledesma-Carbayo, M.J.; Delgado-Goñi, T.; García-Martín, M.L.; Santos, A.; Arús, C.. "Effect of acute hyperglycemia on moderately hypothermic GL261 mouse glioma monitored by T1-weighted DCE MRI". Magnetic Resonance Materials in Physics, Biology and Medicine 28 2 (2015): 119-126. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939879346&partnerID=MN8TOARS.
    10.1007/s10334-014-0447-2
  16. Sanz-Cortes, M.; Egaña-Ugrinovic, G.; Simoes, R.V.; Vazquez, L.; Bargallo, N.; Gratacos, E.. "Association of brain metabolism with sulcation and corpus callosum development assessed by MRI in late-onset small fetuses". American Journal of Obstetrics and Gynecology 212 6 (2015): 804.e1-804.e8. http://www.scopus.com/inward/record.url?eid=2-s2.0-84931562980&partnerID=MN8TOARS.
    10.1016/j.ajog.2015.01.041
  17. Simões, R.V.; Serganova, I.S.; Kruchevsky, N.; Leftin, A.; Shestov, A.A.; Thaler, H.T.; Sukenick, G.; et al. "Metabolic Plasticity of Metastatic Breast Cancer Cells: Adaptation to Changes in the Microenvironment". Neoplasia 17 8 (2015): 671-684. http://www.scopus.com/inward/record.url?eid=2-s2.0-84963957265&partnerID=MN8TOARS.
    10.1016/j.neo.2015.08.005
  18. Simões, R.V.; Sanz-Cortes, M.; Muñoz-Moreno, E.; Gratacós, E.; Vázquez, É.; Bargalló, N.; Fernandez-Zubillaga, A.. "Feasibility and technical features of fetal brain magnetic resonance spectroscopy in 1.5 T scanners". American Journal of Obstetrics and Gynecology 213 5 (2015): 741-742. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946496043&partnerID=MN8TOARS.
    10.1016/j.ajog.2015.06.033
  19. Simões, R.V.; Cruz-Lemini, M.; Bargalló, N.; Gratacós, E.; Sanz-Cortés, M.. "Brain metabolite differences in one-year-old infants born small at term and association with neurodevelopmental outcome". American Journal of Obstetrics and Gynecology 213 2 (2015): 210.e1-210.e11. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937967217&partnerID=MN8TOARS.
    10.1016/j.ajog.2015.04.011
  20. Simões, R.V.; Muñoz-Moreno, E.; Carbajo, R.J.; González-Tendero, A.; Illa, M.; Sanz-Cortés, M.; Pineda-Lucena, A.; Gratacós, E.. "In vivo detection of perinatal brain metabolite changes in a rabbit model of intrauterine growth restriction (IUGR)". PLoS ONE 10 7 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84941904049&partnerID=MN8TOARS.
    10.1371/journal.pone.0131310
  21. Candiota, A.P.; Acosta, M.; Simões, R.V.; Delgado-Goñi, T.; Lope-Piedrafita, S.; Irure, A.; Marradi, M.; et al. "A new ex vivo method to evaluate the performance of candidate MRI contrast agents: A proof-of-concept study". Journal of Nanobiotechnology 12 1 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84899493271&partnerID=MN8TOARS.
    10.1186/1477-3155-12-12
  22. Sanz-Cortes, M.; Simoes, R.V.; Bargallo, N.; Masoller, N.; Figueras, F.; Gratacos, E.. "Proton magnetic resonance spectroscopy assessment of fetal brain metabolism in late-onset 'small for gestational age' versus 'intrauterine growth restriction' fetuses". Fetal Diagnosis and Therapy 37 2 (2014): 108-116. http://www.scopus.com/inward/record.url?eid=2-s2.0-84924341098&partnerID=MN8TOARS.
    10.1159/000365102
  23. Ortuño, J.E.; Ledesma-Carbayo, M.J.; Simões, R.V.; Candiota, A.P.; Arús, C.; Santos, A.. "DCE@urLAB: A dynamic contrast-enhanced MRI pharmacokinetic analysis tool for preclinical data". BMC Bioinformatics 14 1 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84886735382&partnerID=MN8TOARS.
    10.1186/1471-2105-14-316
  24. Delgado-Goñi, T.; Martín-Sitjar, J.; Simões, R.V.; Acosta, M.; Lope-Piedrafita, S.; Arús, C.. "Dimethyl sulfoxide (DMSO) as a potential contrast agent for brain tumors". NMR in Biomedicine 26 2 (2013): 173-184. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872603010&partnerID=MN8TOARS.
    10.1002/nbm.2832
  25. Ortega-Martorell, S.; Lisboa, P.J.G.; Vellido, A.; Simões, R.V.; Pumarola, M.; Julià-Sapé, M.; Arús, C.. "Convex Non-Negative Matrix Factorization for Brain Tumor Delimitation from MRSI Data". PLoS ONE 7 10 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84867858795&partnerID=MN8TOARS.
    10.1371/journal.pone.0047824
  26. Simões, R.V.; Ortega-Martorell, S.; Delgado-Goñi, T.; Fur, Y.L.; Pumarola, M.; Candiota, A.P.; Martín, J.; et al. "Improving the classification of brain tumors in mice with perturbation enhanced (PE)-MRSI". Integrative Biology 4 2 (2012): 183-191. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863049407&partnerID=MN8TOARS.
    10.1039/c2ib00079b
  27. Simões, R.V.; Delgado-Goñi, T.; Lope-Piedrafita, S.; Arús, C.. "1H-MRSI pattern perturbation in a mouse glioma: The effects of acute hyperglycemia and moderate hypothermia". NMR in Biomedicine 23 1 (2010): 23-33. http://www.scopus.com/inward/record.url?eid=2-s2.0-75149164789&partnerID=MN8TOARS.
    10.1002/nbm.1421
  28. Simões, R.V.; García-Martín, M.L.; Cerdán, S.; Arús, C.. "Perturbation of mouse glioma MRS pattern by induced acute hyperglycemia". NMR in Biomedicine 21 3 (2008): 251-264. http://www.scopus.com/inward/record.url?eid=2-s2.0-41949133892&partnerID=MN8TOARS.
    10.1002/nbm.1188
  29. Simões, R.V.; Martinez-Aranda, A.; Martín, B.; Cerdán, S.; Sierra, A.; Arús, C.. "Preliminary characterization of an experimental breast cancer cells brain metastasis mouse model by MRI/MRS". Magnetic Resonance Materials in Physics, Biology and Medicine 21 4 (2008): 237-249. http://www.scopus.com/inward/record.url?eid=2-s2.0-49249127767&partnerID=MN8TOARS.
    10.1007/s10334-008-0114-6
  30. Rodríguez, E.; Simoes, R.V.; Roig, A.; Molins, E.; Nedelko, N.; Slawska-Waniewska, A.; Aime, S.; et al. "An iron-based T1 contrast agent made of iron-phosphate complexes: in vitro and in vivo studies.". Magma (New York, N.Y.) 20 1 (2007): 27-37. http://www.scopus.com/inward/record.url?eid=2-s2.0-34247892415&partnerID=MN8TOARS.
    10.1007/s10334-006-0066-7
Capítulo de livro
  1. Simões RV; Muñoz-Moreno E; Tudela R; Soria G. "1H Spectroscopic Imaging of the Rodent Brain.". In Methods in molecular biology (Clifton, N.J.). 2018.
    10.1007/978-1-4939-7531-0_12
  2. Simões, R.V.; Candiota, A.P.; Julià-Sapé, M.; Arús, C.. "In vivo magnetic resonance spectroscopic imaging and ex vivo quantitative neuropathology by high resolution magic angle spinning proton magnetic resonance spectroscopy". In Methods in molecular biology (Clifton, N.J.). 2013.
    10.1007/7657_2011_31
Tese / Dissertação
  1. Simões, Rui Vasco Portas Ferreira. "Towards molecular imaging of preclinical brain tumor models by MRS : monitoring and analysis of mouse brain glioma MR spectral pattern changes during acute hyperglycemic challenges in vivo". Doutoramento, 2010. http://hdl.handle.net/10316/13879.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/10/03 Lecture on Early Research Career Paths Annual Meeting of the ESMRMB
European Society for Molecular Resonance in Medicine and Biology (ESMRMB) (Barcelona, Espanha)
2024/03/15 New tools to image cancer (ESMI Annual Meeting – Opening Lecture PS 29) 19th European Molecular Imaging Meeting (EMIM)
European Society for Molecular Imaging (ESMI) (Porto, Portugal)
2023/01/25 University of Aveiro, Institute of Biomedicine, Department of Medical Sciences – iBiMED/DCM Winter Seminar Series 2023. Seminar: Probing glioma metabolism with MRI. Aveiro, Portugal. iBiMED/DCM Winter Seminar Series
University of Aveiro, Institute of Biomedicine, Department of Medical Sciences (Aveiro, Portugal)
2022/12/13 Preclinical MRI Lab at i3S ISMRM Iberian Chapter – Iberian Labs
ISMRM Iberian Chapter (Porto, Portugal)
2022/09/28 Preclinical MRS in glioma models (Translational imaging session “Building bridges between preclinical and clinical glioma imaging”) Glioma MRI COST Action (GliMR 2.0) – Annual Meeting 2022
GlimR 2.0 COST Action (Kusadasi, Turquia)
2020/04/20 Dynamic assessment of early metabolic perturbations in glioma-bearing mice using denoised 2H-MRS. Simões RV, Istúriz J, Olesen JL, Jerpersen SN, Shemesh N. 28th Annual Meeting of the ISMRM
ISMRM (Sydney, Austrália)
2018/12/09 Preclinical MR Imaging: Mapping pre-metastatic niches using advanced DW MRI at ultrahigh field Symposium on Imaging Hallmarks of Cancer
European School of Radiology (ESOR) and Champalimaud Foundation (CF) (Lisbon, Portugal)
2017/10/11 MRS and MRSI in small animal models ESMRMB Lectures on MR 2017 – Small Animal MR Imaging
ESMRMB (Barcelona, Espanha)
2017/10/09 Monitorización del metabolismo celular en modelos de enfermedad mediante espectroscopia RM multinuclear: cáncer, restricción de crecimiento fetal y enfermedad de Alzheimer Annual Meeting of the ESMRMB – Spanish Experts Session
ESMRMB (Barcelona, Espanha)
2016/06/10 MR spectroscopy and spectroscopic imaging: from animal models to patients Neurosciences Institute and MR Imaging Platform Sessions
Institut d’Investigacions Biomediques August Pi i Sunyer (IDIBAPS)
2016/04/06 Perinatal brain metabolic profile changes associated with fetal growth restriction PhD in Biochemistry, Molecular Biology and Biomedicine - seminar series
Autonomous University of Barcelona (UAB) (Barcelona, Espanha)
2015/10/12 Simões RV, Sanz-Cortes M, Muñoz-Moreno E, Cruz-Lemini M, Montefusco CV, Vázquez E, Fernandez A, Bargalló N, Llurba E, Gratacós E. Improving the performance of fetal brain magnetic resonance spectroscopy (MRS) at 1.5T in a multicentric study. 25th World Congress on Ultrasound in Obstetrics and Gynecology, ISUOG
ISUOG (Montreal, Canadá)
2015/05/17 Brain metabolic profile changes associated with fetal growth restriction 2015 Conference Series
Andalucian Center for Nanomedicine and Biotechnology (BIONAND) (Malaga, Espanha)
2014/09/14 Simões RV, Sanz-Cortés M, Parés M, González-Tendero A, Gratacós E. In vivo assessment of tissue-specific metabolic changes in the fetal rabbit brain associated with intrauterine growth restriction (IUGR). 24th World Congress on Ultrasound in Obstetrics and Gynecology, International Society of Ultrasound in Obstetrics and Gynecology (ISUOG).
ISUOG (Barcelona, Espanha)
2014/05/12 Simões RV, Sanz-Cortés M, Bargalló N, Figueras F, Gratacós E. Assessment of late-onset IUGR in the fetal brain using 1H-MRS. 22th Annual Meeting of the ISMRM
ISMRM (Milan, Itália)
2013/04/22 Simões RV, Kruchevsky N, Serganova I, Ackerstaff E, Sukenick G, Blasberg R, Koutcher JA. Inhibition of prostate cancer growth by deferiprone. 21th Annual Meeting of the ISMRM.
ISMRM (Salt Lake City UT, Estados Unidos)
2012/07/26 Simões RV, Ackerstaff E, Serganova I, Kruchevsky N, Sukenick G, Blasberg R, Koutcher JA. 13C-MRS reveals metabolic markers of metastatic and non-metastatic phenotype in two isogenic breast cancer cell lines. The Third International Workshop on Metabolic Imaging
University of Pennsylvania (Philadelphia PA, Estados Unidos)
2011/05/23 Tips for Advanced MRI Screening of Mice Annual Meeting of ISMRM – Weekday Educational Course “Mouse Imaging: how to do it faster, cheaper, & better”
ISMRM (Montreal, Canadá)
2010/05/06 Simões RV, Ortega-Martorell S, Delgado-Goñi T, Pumarola M, Candiota AP, Julià-Sapé M, Arús C. Improving tumor classification with MRSI pattern perturbation. IV Annual Meeting of CIBER-BBN
CIBER-BBN (Zaragoza, Espanha)
2010/03/08 Improving tumor classification with MRSI pattern perturbation CRI Annual International Symposium: “Unanswered Questions in Tumour Monitoring”
Cambridge Research Institute (Cambridge, Reino Unido)
2009/10/02 Simões RV, García-Martín ML, Delgado-Goñi T, Candiota A, Lope-Piedrafita, Pumarola M, S, Arús C. Hot-spots in mouse brain gliomas detected by MRSI pattern perturbation and DCE-MRI. 26th Annual Meeting of the ESMRMB
ESMRMB (Antalya, Turquia)
2009/04/24 Dynamics of Regional Metabolic Patterns by 1H MRSI Annual Meeting of the ISMRM – Dynamic NMR Spectroscopy Study Group.
ISMRM (Honolulu, Estados Unidos)
2009/04/20 Simões RV, García-Martín ML, Delgado-Goñi T, Lope-Piedrafita S, Arús C. Unraveling mouse glioma heterogeneity with DCE-T1 MRI and 1H-CSI metabolome pattern perturbation. 17th Annual Meeting of the ISMRM
ISMRM (Honolulu HI, Estados Unidos)
2009/02/17 Simões RV, García-Martín ML, Lope-Piedrafita S, Arús C. Unraveling Mouse glioma heterogeneity with DCE-T1 MRI and 1H-CSI metabolome pattern perturbation. III Annual Meeting of CIBER-BBN.
CIBER-BBN (Zaragoza, Espanha)
2008/10/03 Simões RV, Lope-Piedrafita S, Arús C. Glioma metabolic heterogeneity as monitored by 1H-CSI in mice upon acute hyperglycemic challenge. 25th Annual Meeting of the ESMRMB. Valencia, SPAIN.
ESMRMB (Valencia, Espanha)
2008/09/14 Simões RV, Lope-Piedrafita S, Arús C. CSI-monitored effects of acute hyperglycemia and moderate hypothermia in a glioma mouse models. ISMRM Workshop, “Frontiers of Magnetic Resonance: from tumor cell to cancer patient”
ISMRM (Nice, França)
2008/05/04 Simões RV, Cerdán S, Arús C. Towards in vivo brain tumor phenotyping with proton CSI pattern perturbation. 16th Annual Meeting of the ISMRM.
ISMRM (Toronto, Canadá)
2007/05/20 Simões RV, Garcia-Martín ML, Cerdán S, Arús C. MRS pattern perturbation: a potential tool for improved brain tumor phenotyping in vivo. ISMRM Cancer Study Group – “Hot Topics Session”. ISMRM-ESMRMB Joint Annual Meeting
ISMRM (Berlin, Alemanha)
2006/05/07 Simões RV, Diekmann C, Cerdán S, Arús C. CSI of mouse brain tumors at 7 Tesla with 0.8µl voxel resolution. 14th Scientific Meeting and Exhibition of the ISMRM
ISMRM (Seattle, Estados Unidos)
2005/09/16 Simões RV, Martinez A, Cerdán S, Sierra A, Arús C. Progression of Human Brain Metastasis in Nude Mice: Preliminary characterization by MRI/MRS. 22nd Annual Meeting of the ESMRMB
ESMRMB (Basel, Suiça)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2017/01/01 - 2017/07/20 MS Thesis title: Development of a tool for automatic analysis of magnetic resonance spectroscopy data: application to the study of regional and longitudinal changes of brain metabolic profile in a transgenic rat model of Alzheimer’s disease. Directors: Raúl Tudela PhD and Rui V. Simões PhD. Institution: University of Barcelona.
Orientador
 Master in Biomedical Engineering.

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2024/10/03 - 2024/10/03 ESMRMB Annual Meeting – Community-initiates Symposium “Iberian MR Networks” (2024/10/03 - 2024/10/03)
Conferência (Presidente da Comissão Organizadora)
 European Society for Magnetic Resonance in Medicine and Biology (ESMRMB), Áustria
2024/07/02 - 2024/07/03 4th Annual Meeting of the ISMRM Iberian Chapter (Local Organizer and Program Chair) (2024/07/02 - 2024/07/03)
Congresso (Presidente da Comissão Organizadora)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/07/01 - 2024/07/01 Porto Translational MRI: Neuro (2024/07/01 - 2024/07/01)
Encontro (Presidente da Comissão Organizadora)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/05/03 - 2023/05/05 GliMR 2.0 COST Action Annual Meeting 2024 (Local Host and Program Committee member) (2023/05/03 - 2023/05/05)
Encontro
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2022/12/15 - 2022/12/15 ISMRM Iberian Chapter – Iberian Labs: Presentation of the Preclinical MRI Lab at i3S
Encontro
 ISMRM Iberian Chapter – Iberian Labs
International Society for Magnetic Resonance in Medicine, Estados Unidos

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2016/07/20 Towards an automated analysis pipeline for MRS data: a prototype based on brain tumors". Directors: Margarida Julià-Sapé PhD, Alfredo Vellido PhD, and Carles Arús PhD. Jury: Diana Sima PhD, Dionisio Acosta PhD, and Rui V. Simões PhD
Arguente
 Victor Mocioiu (Doutoramento)
Universitat Autònoma de Barcelona, Espanha

Arbitragem científica em conferência

Nome da conferência Local da conferência
2024/03/12 - 2024/03/15 19th European Molecular Imaging Meeting Fabian Kiessling, University of Aachen, Germany
2023/07/04 - 2023/07/05 ISMRM Iberian Chapter 3rd Annual Meeting Carlos Alberola-López, Universityy of Valladolid. Spain
2022/06/27 - 2022/06/28 ISMRM Iberian Chapter 2nd Annual Meeting Rita Nunes, Instituto Superior Técnico, Lisbon, Portugal
2021/06/16 - 2021/06/17 ISMRM Iberian Chapter 1st Annual Meeting Diego Hernando, University of Wisconsin-Madison, USA

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2014/10/01 - 2014/10/25 Master of Science and Healthcare of Laboratory Animals. Module 6, in vivo NMR. Autonomous University of Barcelona, Spain. 2014 Master of Science and Healthcare of Laboratory Animals (Master) Universitat Autònoma de Barcelona Facultat de Veterinària, Espanha
2008/10/01 - 2008/10/25 Master of Science and Healthcare of Laboratory Animals. Module 6, in vivo NMR. Autonomous University of Barcelona, Spain. Master of Science and Healthcare of Laboratory Animals (Master) Universitat Autònoma de Barcelona Facultat de Veterinària, Espanha

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2023/09/04 Preclinical MRI for translational imaging at i3S (Article in i3S Newsletter) i3S Newsletter #96

Tutoria

Tópico Nome do aluno
2023/06/01 - 2023/08/31 Preclinical MRI of mouse models Maria Lima
2016/05/01 - 2019/12/01 Erasmus Mundus Doctorate in Fetal and Perinatal Medicine Lina Yousse
Distinções

Prémio

2017 Best abstract award: International Symposium on Diabetes, Hypertension, Metabolic Syndrome & Pregnancy. Barcelona, Spain.

Título

2020 Secretary Elected: ISMRM Iberian Chapter
International Society for Magnetic Resonance in Medicine, Estados Unidos

Outra distinção

2023 GliMR 2.0 Researcher of the month
2018 Seal of Excellence Certificate: H2020-MSCA-IF-2017
European Commission, Bélgica
2017 Front cover (Simões et al. AJOG 2017: issue 1, January)
2015 Best short oral presentation award. ISUOG Meeting. Montreal, CANADA.
2015 Featured Article (http://www.ajog.org/featured)
2014 summa cum laude award for Oral Talk. Joint Annual Meeting ISMRM-ESMRMB. Milan, ITALY.
International Society for Magnetic Resonance in Medicine, Estados Unidos
2013 Abstract award. ISMRM 21th Meeting. Salt Lake City UT, USA.
2012 Student award for Oral Presentation. Philadelphia PA, USA.
2012 Scholar-in-training grantee award. San Antonio TX, USA.
2010 Invited speaker. Annual International Symposium “Unanswered Questions in Tumour Monitoring”. Cambridge, UK
Cambridge Research Institute, Estados Unidos
2009 Student support program. ESMRMB 26th Scientific Meeting & Exhibition, Antalya, Turkey
2009 Invited speaker. Dynamic NMR Spectroscopy Study Group, ISMRM. Honolulu HI, USA.
International Society for Magnetic Resonance in Medicine, Estados Unidos
2008 Educational stipend. ISMRM 16th Scientific Meeting & Exhibition, Toronto/Canada.
International Society for Magnetic Resonance in Medicine, Estados Unidos
2007 Educational stipend. Joint Annual Meeting ISMRM-ESMRMB, Berlin/Germany.
International Society for Magnetic Resonance in Medicine, Estados Unidos
2006 Educational stipend. ISMRM 14th Scientific Meeting & Exhibition, Seattle/USA.
International Society for Magnetic Resonance in Medicine, Estados Unidos
2005 PhD Grant
2005 Student support program. ESMRMB 22nd Meeting, Basle/Switzerland
2004 Beca de Formación de Personal Investigador
2003 Beca de Formació i Suport a la Investigació, projecte MEDIVO
2002 Under-graduate internship grant, PRODEP III