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Sylvain Ladame. Published 8 articles in journals. Works in the area(s) of Engineering and Technology with emphasis on Medical Engineering. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: nucleic acids; biosensor; fluorescence; peptide nucleic acid; molecular targeting; therapeutic; diagnostics; .
Identificação

Identificação pessoal

Nome completo
Sylvain Ladame

Nomes de citação

  • Ladame, Sylvain

Identificadores de autor

Ciência ID
2F16-ABED-669E
ORCID iD
0000-0002-3358-9638

Telefones

Telefone
  • (+44) 0207594530 (Profissional)

Moradas

  • Imperial College London, Department of Bioengineering, South Kensington Campus, SW7 2AZ, London, London, Reino Unido (Profissional)

Websites

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Engenharia Médica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Francês (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Formação
Grau Classificação
1997/09/01 - 2001/06/22
Concluído
 chimie des biomolecules (Doctorat)
Université Toulouse III Paul Sabatier, França
1996/09/01 - 1997/06/30
Concluído
 Chimie des Biomolecules (DEA)
Université Toulouse III Paul Sabatier, França
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2006/09/01 - 2010/06/30 Investigador principal (carreira) (Investigação) Centre National de la Recherche Scientifique, França
Institut de Science et d'Ingénierie Supramoléculaires, França

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2010/07/01 - Atual Leitor (Docente Universitário) Imperial College London, Reino Unido
Imperial College London, Reino Unido
Projetos

Bolsa

Designação Financiadores
2018/06/15 - 2020/09/30 Engineering and validation of a modular and non-invasive screening tool for Cancer based on automated microRNA profiling from whole blood with paper-hydrogel electrochemical sensors
C49996/A26141
Investigador responsável
Imperial College London, Reino Unido
 Cancer Research UK
Em curso
2012/06/01 - 2015/05/31 G-quadruplexes in gene promoters and untranslated regions: myth or reality
RPG-2012-603
Investigador responsável
Imperial College London, Reino Unido
Concluído

Outro

Designação Financiadores
2019/07/01 - 2022/06/30 Engineering of a predictive point-of-care test for preterm birth based on automated microRNA profiling on paper
WSCR_P80733
Investigador responsável
Imperial College London, Reino Unido
 March of Dimes Foundation
Em curso
Produções

Publicações

Artigo em revista
  1. Dana Al Sulaiman; Jason Y. H. Chang; Nitasha R. Bennett; Helena Topouzi; Claire A. Higgins; Darrell J. Irvine; Sylvain Ladame. "Hydrogel-Coated Microneedle Arrays for Minimally Invasive Sampling and Sensing of Specific Circulating Nucleic Acids from Skin Interstitial Fluid". ACS Nano (2019): https://doi.org/10.1021/acsnano.9b04783.
    10.1021/acsnano.9b04783
  2. Philip Gillespie; Sylvain Ladame; Danny O'Hare. "Molecular methods in electrochemical microRNA detection". The Analyst (2019): https://doi.org/10.1039/C8AN01572D.
    10.1039/C8AN01572D
  3. Suraj Pavagada; Robert B. Channon; Jason Y. H. Chang; Sung Hye Kim; David MacIntyre; Phillip R. Bennett; Vasso Terzidou; Sylvain Ladame. "Oligonucleotide-templated lateral flow assays for amplification-free sensing of circulating microRNAs". Chemical Communications 55 83 (2019): 12451-12454. https://doi.org/10.1039/C9CC05607F.
    10.1039/C9CC05607F
  4. Dana Al Sulaiman; Paolo Cadinu; Aleksandar P. Ivanov; Joshua B. Edel; Sylvain Ladame. "Chemically Modified Hydrogel-Filled Nanopores: A Tunable Platform for Single-Molecule Sensing". Nano Letters (2018): https://doi.org/10.1021/acs.nanolett.8b03111.
    10.1021/acs.nanolett.8b03111
  5. Dana Al Sulaiman; Jason Y. H. Chang; Sylvain Ladame. "Subnanomolar Detection of Oligonucleotides through Templated Fluorogenic Reaction in Hydrogels: Controlling Diffusion to Improve Sensitivity". Angewandte Chemie International Edition 56 19 (2017): 5247-5251. https://doi.org/10.1002/anie.201701356.
    10.1002/anie.201701356
  6. Dana Al Sulaiman; Jason Y. H. Chang; Sylvain Ladame. "Subnanomolar Detection of Oligonucleotides through Templated Fluorogenic Reaction in Hydrogels: Controlling Diffusion to Improve Sensitivity". Angewandte Chemie 129 19 (2017): 5331-5335. https://doi.org/10.1002/ange.201701356.
    10.1002/ange.201701356
  7. Metcalf GA; Shibakawa A; Patel H; Sita-Lumsden A; Zivi A; Rama N; Bevan CL; Ladame S. "Amplification-Free Detection of Circulating microRNA Biomarkers from Body Fluids Based on Fluorogenic Oligonucleotide-Templated Reaction between Engineered Peptide Nucleic Acid Probes: Application to Prostate Cancer Diagnosis.". Analytical chemistry (2016): http://europepmc.org/abstract/med/27498854.
    10.1021/acs.analchem.6b01594
  8. Zuffo M; Doria F; Spalluto V; Ladame S; Freccero M. "Red/NIR G-Quadruplex Sensing, Harvesting Blue Light by a Coumarin-Naphthalene Diimide Dyad.". Chemistry (Weinheim an der Bergstrasse, Germany) (2015): http://europepmc.org/abstract/med/26463116.
    10.1002/chem.201503020