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Sofia Melo Pereira is a PhD in Cellular and Molecular Physiology, currently self-employed and learning programming languages, such as Python (Data Science, Pandas, NumPy, Web Scraping), HTML and CSS (web development). She is experienced in scientific project management with a strong cell/molecular biology background and multidisciplinary training: aging, cell cycle, human genetics, stem cells, biomaterial science and developmental biology. In the past years, Sofia has worked as a researcher in biomedical sciences with focus on finding alternative therapeutic approaches to improve quality of late life in elderly people by delaying the onset of age-related diseases. Previous to post-doctoral research, Sofia was the scientific communication manager at CGC Genetics (Porto, PT), responsible for all written scientific communication in the company and the Science and Technological Manager in a Marie Curie ITN (University of Liverpool, UK) and taught as a University demonstrator in courses such as Biostatistics, Animal Physiology and Basic Laboratory.
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Identificação

Identificação pessoal

Nome completo
Sofia Melo Pereira
Data de nascimento
1987/06/03
Género
Feminino

Nomes de citação

  • Pereira, SM

Identificadores de autor

Ciência ID
3715-08D4-DFEF
ORCID iD
0000-0001-8335-846X

Endereços de correio eletrónico

  • spereira@ibmc.up.pt (Profissional)

Telefones

Telefone
  • 220408800 (Profissional)

Moradas

  • i3S, Instituto de Investigação e Inovação da Universidade do Porto. Rua Alfredo Allen, 208, 4200-135, Porto, Porto, Portugal (Profissional)

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Diagnóstico e Terapias de Base Genética
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Médicas e da Saúde - Medicina Básica - Genética Humana

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Português Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Formação
Grau Classificação
2011/06/01 - 2015/04/01
Concluído
 PhD Programme in Cellular and Molecular Physiology (Doctor of Philosophy)
University of Liverpool Department of Cellular and Molecular Physiology, Reino Unido
"Magnetic reporter genes for MRI-based stem cell tracking" (TESE/DISSERTAÇÃO)
 n/a
2011
Concluído
 Biotecnologia para as Ciências da Saúde (Mestrado integrado)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
"Development of models to determine dynamic GNE expression in vivo to aid resolution of sialic acid dysfunction associated with Hereditary Inclusion Body Myopathy" (TESE/DISSERTAÇÃO)
 17 (de 20)
2008
Concluído
 Genética e Biotecnologia (Licenciatura)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
"Regenerative Medicine – Periodontal Ligament Engineering " (TESE/DISSERTAÇÃO)
 14 (de 20)
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2018/06/15 - 2019/12/31 Pós-doutorado (Investigação) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016/12/01 - 2018/05/31 Pós-doutorado (Investigação) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2011/06/01 - 2015/04/01 Estagiário de Investigação (Investigação) University of Liverpool Department of Cellular and Molecular Physiology, Reino Unido
2012/03/01 - 2014/09/01 Gestão de Ciência e Tecnologia University of Liverpool Department of Cellular and Molecular Physiology, Reino Unido
2009/09/15 - 2011/02/01 Estagiário de Investigação (Investigação) Instituto Gulbenkian de Ciência, Portugal
2008/05/01 - 2008/07/31 Estagiário de Investigação (Investigação) Biomaterials Biodegradables and Biomimetics, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2012/12/01 - 2013/12/31 Monitor (Docente Universitário) University of Liverpool School of Health Sciences, Reino Unido

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2015/04/01 - 2016/06/01 Science Communication Manager CGC Genetics Centro de Genética Clínica, Portugal
2007/08/01 - 2007/08/31 Summer Traineeship Clinical & Diagnostic Human Cytogenetics Universidade do Porto Faculdade de Medicina, Portugal
Projetos

Bolsa

Designação Financiadores
2018/06/15 - 2019/12/31 Assessing the role of FoxM1 repression in age-associated mitotic phenotypes
PTDC/BEX-BCM/2090/2014
Investigador Pós-doutorado
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2016/12/01 - 2018/05/31 Adaptive potential of aneuploidy in cancer
NORTE-01-0145- FEDER-000029 – Research line 2
Investigador Pós-doutorado
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
European Commission - H2020
Concluído
2015/04 - 2016/06 Internacionalização CGC Genetics - Consolidação de mercados actuais e Novos Mercados (China, Macau e Rússia)
POCI-02-0752-FEDER-007806
NORTE-01-0145- FEDER-000029 – Research line 2
Bolseiro de Gestão de Ciência e Tecnologia
CGC Genetics Centro de Genética Clínica, Portugal
 Portugal 2020
Concluído

Projeto

Designação Financiadores
2011/06/01 - 2015/04/01 Magnetic reporter genes for MRI-based cell tracking
PERG08-GA-2010-276909
Bolseiro de Doutoramento
University of Liverpool, Institute of Translational Medicine, Reino Unido
 University of Liverpool, Institute of Translational Medicine

EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Concluído
2012/03/01 - 2014/09/30 The potential of human kidney stem/progenitor cells for use in drug discovery and regenerative therapy programmes. | FP7 Initial Training Network: “NephroTools”
"NephroTools"
Bolseiro de Gestão de Ciência e Tecnologia
University of Liverpool Institute of Translational Medicine, Reino Unido
 European Commission Seventh Framework Programme for Research and Technological Development People

EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Concluído
Produções

Publicações

Artigo em revista
  1. Pereira, SM; Ribeiro, R; Logarinho, E. "Approaches towards longevity: reprogramming, senolysis and improved mitotic competence as anti-aging therapies". International Journal of Molecular Sciences (2019): https://www.mdpi.com/1422-0067/20/4/938.
    Acesso aberto • Publicado
  2. Mournetas, V; Pereira, SM; Fernig, DG; Murray, P. "A descriptive guide for absolute quantification of produced shRNA pseudotyped lentiviral particles by real-time PCR". Journal of Biological Methods 3 4 (2016): http://dx.doi.org/10.14440/jbm.2016.142.
    Acesso aberto • Publicado • 10.14440/jbm.2016.142
  3. Pereira, SM; Williams, SR; Murray, P; Taylor, A. "MS-1 magA: Revisiting Its Efficacy as a Reporter Gene for MRI". Molecular Imaging 15 (2016): http://dx.doi.org/10.1177/1536012116641533.
    Acesso aberto • Publicado • 10.1177/1536012116641533
  4. Pereira, SM; Herrmann, A; Moss, D; Poptani, Harish; Williams, SR; Murray, P; Taylor, A. "Evaluating the effectiveness of transferrin receptor-1 (TfR1) as a magnetic resonance reporter gene". Contrast Media & Molecular Imaging 11 3 (2016): 236-244. http://dx.doi.org/10.1002/cmmi.1686.
    Acesso aberto • Publicado • 10.1002/cmmi.1686
  5. Nogueira, R; Pinto-Ribeiro, F; Pereira, SM; Valente, F. "Macroscopic and Histopathological Study of the Placenta - An Essential Resource in Litigation Processes". Journal of Clinical Research & Bioethics 06 06 (2015): http://dx.doi.org/10.4172/2155-9627.1000247.
    Acesso aberto • Publicado • 10.4172/2155-9627.1000247
  6. Pereira, SM; Moss, D; Williams, SR; Murray, P; Taylor, A. "Overexpression of the MRI Reporter Genes Ferritin and Transferrin Receptor Affect Iron Homeostasis and Produce Limited Contrast in Mesenchymal Stem Cells". International Journal of Molecular Sciences 16 12 (2015): 15481-15496. http://dx.doi.org/10.3390/ijms160715481.
    Acesso aberto • Publicado • 10.3390/ijms160715481
Poster em conferência
  1. Pereira, Sofia. "A Case Report of Parental Transmission of Koolen-De Vries Syndrome.". Trabalho apresentado em American College of Medical Genetics, Florida, USA, 2016.
  2. Pereira, Sofia. "A case report of 6p25p22 duplication associated with BOFs clinical features.". Trabalho apresentado em European Society of Human Genetics, Barcelona, Spain, 2016.
  3. Pereira, Sofia. "Intragenic CASK deletion found in mosaicism in a female patient.". Trabalho apresentado em European Society of Human Genetics, Barcelona, Spain, 2016.
  4. Pereira, Sofia. "Disease exome, a powerful diagnostic tool: post-mortem diagnosis of dyskeratosis congenita". Trabalho apresentado em European Society of Human Genetics, Barcelona, Spain, 2016.
  5. Pereira, Sofia. "A placenta gemelar: corionicidade e tipo de inserção dos cordões.". Trabalho apresentado em Associação Portuguesa de Diagnóstico Pré-Natal, Lisboa, Portugal, 2015.
  6. Pereira, Sofia. "Array CGH em Diagnóstico Pré-Natal.". Trabalho apresentado em Associação Portuguesa de Diagnóstico Pré-Natal, Lisboa, Portugal, 2015.
  7. Pereira, Sofia. "A case report of Parental Transmission of Koolen-de Vries Syndrome.". Trabalho apresentado em Sociedade Portuguesa de Genética Humana, Porto, Portugal, 2015.
  8. Pereira, Sofia. "A Autópsia Fetal no Estudo dos Defeitos Cardíacos Congénitos.". Trabalho apresentado em Sociedade Portuguesa de Obstetrícia e Medicina Materno-Fetal, Coimbra, Portugal, 2015.
  9. Pereira, Sofia. "Magnetic reporter system for MRI tracking of cells.". Trabalho apresentado em University of Liverpool and University of Manchester Inter-University Physiology and Cell Biology Postgraduate Symposium, Liverpool UK, 2014.
  10. Pereira, SM. "Are reporter genes feasible for the MRI Tracking of Stem Cells? (Poster 5)". Trabalho apresentado em 1st NephroTools International Conference, The Kidney: Development, Disease and Novel Therapies., Liverpool UK, 2013.
    10.11159/icnb16.102
  11. Pereira, Sofia. "MRI Tracking of “Magnetic” Stem Cells.". Trabalho apresentado em University Poster Day 2013, University of Liverpool, UK, 2013.
  12. Pereira, Sofia. "Ferritin and MagA as reporter genes for MRI tracking of Stem Cells.". Trabalho apresentado em Life Sciences PhD Conference, University of Manchester, UK, 2013.
  13. Pereira, Sofia. "Are reporter genes feasible for MRI tracking of Stem Cells? (BIOMATERIALS SCIENCE POSTER AWARD)". Trabalho apresentado em Symposium on Nanoparticle-based Technologies for Cell Tracking, University of Liverpool, UK, 2013.
  14. Pereira, Sofia. "Are reporter genes feasible for the MRI Tracking of Stem Cells?". Trabalho apresentado em 4rd Annual Scientific Meeting of the Mercia Stem Alliance, Keele University, UK, 2013.
  15. Pereira, Sofia. "Reporter genes for the MRI Tracking of Stem Cells. (Poster 34)". Trabalho apresentado em University of Liverpool and University of Manchester Inter-University Physiology and Cell Biology Postgraduate Symposium, Liverpool UK, 2012.
  16. Pereira, Sofia. "MagA – A potential or a restraint reporter gene for MRI tracking of stem cells?". Trabalho apresentado em 3rd Annual Scientific Meeting of the Mercia Stem Alliance, University of Nottingham, UK, 2012.
  17. Pereira, Sofia. "Reporter genes for the MRI Tracking of Stem Cells.". Trabalho apresentado em 2nd Annual Scientific Meeting of the Mercia Stem Alliance, University of Manchester UK, 2011.
Resumo em conferência
  1. Pereira, Sofia. "Disease exome, a powerful diagnostic tool: post-mortem diagnosis of dyskeratosis congenita (P03.39)". Trabalho apresentado em European Human Genetics Conference 2016, Barcelona, 2016.
    Publicado
  2. Pereira, Sofia. "A case report of 6p25p22 duplication associated with BOFs clinical features (P11.022)". Trabalho apresentado em European Human Genetics Conference 2016, Barcelona, 2016.
    Publicado
  3. Pereira, Sofia. "Intragenic CASK deletion found in mosaicism in a female patient (P11.080)". Trabalho apresentado em European Human Genetics Conference 2016, Barcelona, 2016.
    Publicado
  4. Pereira, Sofia. "A Case Report of Parental Transmission of Koolen-De Vries Syndrome". Trabalho apresentado em American College of Medical Genetics 2016, Tampa, Florida, 2016.
    Publicado
  5. Pereira, Sofia. "Are reporter genes feasible for the MRI Tracking of Stem Cells?". Trabalho apresentado em Future Investigators Regenerative Medicine (FIRM) Conference, Girona, 2013.
    Publicado
Tese / Dissertação
  1. Pereira, Sofia. "Magnetic reporter genes for MRI-based stem cell tracking". Doutoramento, University of Liverpool Department of Cellular and Molecular Physiology, 2015. https://livrepository.liverpool.ac.uk/2009422/.
  2. Pereira, Sofia. "Development of models to determine dynamic GNE expression in vivo to aid resolution of sialic acid dysfunction associated with Hereditary Inclusion Body Myopathy". Mestrado, 2011. http://hdl.handle.net/10348/717.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2017 Amelioration of Hutchison-Gilford Progeria Syndrome ageing hallmarks by transcriptional modulation 6th i3S Annual Meeting.
Instituto de Investigação e Inovação em Saúde da Universidade do Porto (Póvoa, Portugal)
2015 Magnetic reporter genes for MRI-based stem cell tracking Pre-VIVA public presentation.
University of Liverpool, Department of Cellular and Molecular Physiology (Liverpool, Reino Unido)
2014 Lentiviral approaches to knock-in and knock-down genes of interest 1st Young Investigators Workshop of MSCA
Mercia Stem Cell Alliance (Liverpool, Reino Unido)
2013 Are reporter genes feasible for the MRI Tracking of Stem Cells? Future Investigators Regenerative Medicine (FIRM) Symposium
(Girona, Espanha)
2013 Ferritin and MagA as reporter genes for the MRI Tracking of Stem Cells. 17th Annual Nephrogenesis Workshop
University of Edinburgh (Edinburgh, Reino Unido)
2012 Limitations of MagA as a reporter gene for MRI tracking of Stem Cells Annual Postgraduate Seminars
University of Liverpool, Department of Cellular and Molecular Physiology (Liverpool, Reino Unido)
2011 Development of models to determine dynamic GNE expression in vivo to aid resolution of sialic acid dysfunction associated with HIBM. Master Pre-Defence Presentation
Universidade de Trás-os-Montes e Altou Douro (Vila Real, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2017/12/01 - 2018/01/01 Amelioration of HGPS aging hallmarks by cyclic induction of FoxM1 transcriptional activity
Coorientador de Rui Oliveira
 Medicine (Licenciatura/Bacharelato)
Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2017/05/01 - 2017/06/30 Ascertain FOXM1 role in modulation of epigenetic alterations in HGPS
Coorientador de Bibiana Silva
 Master of Science (MSc) Student in Cellular and Molecular Biology (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014/04/01 - 2014/06/30 Investigating the effect of MagA as a reporter gene on HEK 293TN
Orientador de Maria Christofi
 Masters of Research (MRes) Student in Biomedical Sciences – Molecular and Cellular Physiology. (Mestrado)
University of Liverpool School of Health Sciences, Reino Unido
2014/01/01 - 2014/03/31 Effect of overexpressed effects of Transferrin Receptor-1 and MagA overexpressed genes on CHO K1 cells
Orientador de Maria Christofi
 Masters of Research (MRes) Student in Biomedical Sciences – Molecular and Cellular Physiology. (Mestrado)
University of Liverpool School of Health Sciences, Reino Unido
2013/09/01 - 2013/12/31 Master-level project design and laboratory work supervision
Orientador de Zohra Butt
 Masters of Research (MRes) Student in Biomedical Sciences – Molecular and Cellular Physiology (Mestrado)
University of Liverpool School of Health Sciences, Reino Unido

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2014/09/18 - 2014/09/19 Organized 1st MCSA Young Investigators Workshop - "Lentiviral approaches to knock-in and knock-down genes of interest" – Liverpool, UK (2014/09/18 - 2014/09/19)
Oficina (workshop) (Membro da Comissão Organizadora)
 University of Liverpool Institute of Translational Medicine, Reino Unido

Mercia Stem Cell Alliance, Reino Unido
2014/09/18 - 2014/09/19 5th Annual meeting of Mercia Stem Cell Alliance This is a UK-based conferences, holding more than 200 delegates and 15 sponsoring parties (2014/09/18 - 2014/09/19)
Conferência (Membro da Comissão Organizadora)
 Mercia Stem Cell Alliance, Reino Unido

University of Liverpool Institute of Translational Medicine, Reino Unido

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2018/05/07 - 2018/05/18 Course in Laboratory Animal Science – FELASA, Category C
Seminário
 XXV Edition in Laboratory Animal Science
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2012/10/01 - 2012/12/31 Biotechnology Young Entrepreneurs Scheme Competition - "Biotech YES" International postgraduate training course and competition to create a business plan which is presented to a panel of Venture Capitalists, Patent Attorneys and Scientific Officers.
Outro
 Biotechnology Young Entrepreneurs Scheme Competition - "Biotech YES"
Biotechnology and Biological Sciences Research Council, Reino Unido
2012/10/01 - 2012/10/15 International Curie/UPMC Developmental Biology Course
Seminário
 International Curie/UPMC Developmental Biology Course
Sorbonne Université Campus Pierre et Marie Curie, França

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2015/04/06 - 2016/06/01 International scientific written communication, such scientific marketing, publications (paper/poster/abstract), planning of international conference participation, workshop organization, application to calls and funding opportunities and scientific customer care support. Applying for funding outside academia provided me with experience in developing and managing schedules, identifying goals and tasks to be accomplished in a realistic timeline. CGC Genetics Centro de Genética Clínica, Portugal
2012/03/01 - 2014/09/30 Project Administrator FP7 Initial Training Network NephroTools: "The potential of human kidney stem/progenitor cells for use in drug discovery and regenerative therapy programmes" As part of administrator of an EU Network, comprehending 12 academic and industrial partners, my main duties included on assisting with the recruitment of researchers, addressing applications to check eligibility criteria and requesting references as appropriate. University of Liverpool Department of Cellular and Molecular Physiology, Reino Unido

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2012/12/01 - 2013/12/31 Basic Laboratory Skills (Bachelor) University of Liverpool School of Health Sciences, Reino Unido
2012/12/01 - 2013/12/31 Biostatistics (Bachelor) University of Liverpool School of Life Sciences, Reino Unido
2012/12/01 - 2013/12/31 Animal Physiology (Bachelor) University of Liverpool School of Life Sciences, Reino Unido

Membro de associação

Nome da associação Tipo de participação
2011/01/01 - 2014/12/31 British Society for Cell Biology Member
2011/01/01 - 2014/12/31 British Society for Developmental Biology Member

Tutoria

Tópico Nome do aluno
2018/08/01 - 2018/08/31 Project design and laboratory work supervision Rafaela Oliveira
Distinções

Prémio

2013 Biomaterials Science Poster Award, Symposium on Nanoparticle-based Technologies for Cell Tracking
University of Liverpool Department of Cellular and Molecular Physiology, Reino Unido
2013 Travel Grant Award by the British Society for Cell Biology
British Society for Cell Biology, Reino Unido

Título

2013 University of Liverpool PhD Representative & Co-Founder Young Investigators Committee of Mercia Stem Cell Alliance (MSCA)
University of Liverpool Department of Cellular and Molecular Physiology, Reino Unido

Mercia Stem Cell Alliance, Reino Unido