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Identificação

Identificação pessoal

Nome completo
Young-Bum Kim

Nomes de citação

  • Kim, Young-Bum

Identificadores de autor

Ciência ID
461F-A1BD-6501
ORCID iD
0000-0001-9471-6330
Formação
Grau Classificação
1991 - 1996
Concluído
 Molecular Physiology (Doktor (PhD))
Tsukuba Daigaku - Tsukuba Campus Kasuga Chiku, Japão
"Mechanism of body fat accumulation in obese rats induced by a high-fat diet" (TESE/DISSERTAÇÃO)
1991 - 1993
Concluído
 Molecular physiology (Master)
Tsukuba Daigaku, Japão
1984 - 1986
Concluído
 Nutrition Science (Master)
Konkuk University, Coreia do Sul
1980 - 1984
Concluído
 Nutrition Science (Bachelor)
Konkuk University, Coreia do Sul
Percurso profissional

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2020 - Atual Invited Professor Gachon University, Coreia do Sul
2012/09 - Atual Associate Profesor Beth Israel Deaconess Medical Center, Estados Unidos
2014 - 2021 Invited Professor Seoul National University, Coreia do Sul
2007 - 2016 Adjunct Professor Gachon University - Medical Campus, Coreia do Sul
2003/09 - 2012/08 Assistant Professor Beth Israel Deaconess Medical Center, Estados Unidos
1999/09 - 2003/08 Instructor Beth Israel Deaconess Medical Center, Estados Unidos
Projetos

Bolsa

Designação Financiadores
2020/05 - 2024/04 Control of leptin transport system by LRP
R01DK123002
 National Institute of Diabetes and Digestive and Kidney Diseases
2016/09 - 2021/07 ApoJ as a novel hepatokine targeting muscle glucose metabolism
R01DK111529
 National Institute of Diabetes and Digestive and Kidney Diseases
2017/07 - 2021/06 Control of Energy Balance by ApoJ Signaling
R01DK106076
 National Institute of Diabetes and Digestive and Kidney Diseases
2010/03 - 2020/02 ROCK1 signaling in glucose metabolism
R01DK083567
 National Institute of Diabetes and Digestive and Kidney Diseases
2016/08 - 2018/05 Control of glycemia by the CNS
1-SRA-2016-264-S-B
 JDRF
2012/05 - 2016/09 Leptin Signaling in Hypothalamic Neurons and Glutamate Receptors
R01DK094040
 National Institute of Diabetes and Digestive and Kidney Diseases
2012/07 - 2016/06 Clusterin as a Novel Regulator of Adiposity
7-12-BS-094
 American Diabetes Association
2012/07 - 2015/06 Rho-kinase as a novel regulator of adiposity
12GRNT12040170
 American Heart Association Inc
2006/07 - 2009/06 In vivo role of Rho-kinase in glucose metabolism
R21DK075943
 National Institute of Diabetes and Digestive and Kidney Diseases
Produções

Publicações

Artigo em revista
  1. Inês Sousa-Lima; Hyun Jeong Kim; John Jones; Young-Bum Kim. "Rho-Kinase as a Therapeutic Target for Nonalcoholic Fatty Liver Diseases". Diabetes & Metabolism Journal 45 5 (2021): 655-674. https://doi.org/10.4093/dmj.2021.0197.
    10.4093/dmj.2021.0197
  2. Duquenne, Manon; Folgueira, Cintia; Bourouh, Cyril; Millet, Marion; Silva, Anisia; Clasadonte, Jérôme; Imbernon, Monica; et al. "Leptin brain entry via a tanycytic LepR–EGFR shuttle controls lipid metabolism and pancreas function". Nature Metabolism 3 8 (2021): 1071-1090. http://dx.doi.org/10.1038/s42255-021-00432-5.
    10.1038/s42255-021-00432-5
  3. Muñoz, Vitor R.; Gaspar, Rafael C.; Severino, Matheus B.; Macêdo, Ana P. A.; Simabuco, Fernando M.; Ropelle, Eduardo R.; Cintra, Dennys E.; et al. "Exercise Counterbalances Rho/ROCK2 Signaling Impairment in the Skeletal Muscle and Ameliorates Insulin Sensitivity in Obese Mice". Frontiers in Immunology 12 (2021): http://dx.doi.org/10.3389/fimmu.2021.702025.
    10.3389/fimmu.2021.702025
  4. Kang, Min-Cheol; Seo, Ji A; Lee, Hyon; Uner, Aykut; Yang, Won-Mo; Cruz Rodrigues, Kellen Cristina da; Kim, Hyun Jeong; et al. "LRP1 regulates food intake and energy balance in GABAergic neurons independently of leptin action". American Journal of Physiology-Endocrinology and Metabolism 320 2 (2021): E379-E389. http://dx.doi.org/10.1152/ajpendo.00399.2020.
    10.1152/ajpendo.00399.2020
  5. Kang, Gil Myoung; Min, Se Hee; Lee, Chan Hee; Kim, Ji Ye; Lim, Hyo Sun; Choi, Min Jeong; Jung, Saet-Byel; et al. "Mitohormesis in Hypothalamic POMC Neurons Mediates Regular Exercise-Induced High-Turnover Metabolism". Cell Metabolism 33 2 (2021): 334-349.e6. http://dx.doi.org/10.1016/j.cmet.2021.01.003.
    10.1016/j.cmet.2021.01.003
  6. Inês Sousa-Lima; Ana B. Fernandes; Rita S. Patarrão; Young-Bum Kim; M. Paula Macedo. "S-Nitrosoglutathione Reverts Dietary Sucrose-Induced Insulin Resistance". Antioxidants 9 9 (2020): 870-870. https://doi.org/10.3390/antiox9090870.
    10.3390/antiox9090870
  7. Seo, Ji A.; Kang, Min-Cheol; Yang, Won-Mo; Hwang, Won Min; Kim, Sang Soo; Hong, Soo Hyun; Heo, Jee-In; et al. "Author Correction: Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity". Nature Communications 11 1 (2020): http://dx.doi.org/10.1038/s41467-020-16305-6.
    10.1038/s41467-020-16305-6
  8. Aykut Göktürk Üner; Onur Keçik; Paula G. F. Quaresma; Thiago M. De Araujo; Hyon Lee; Wenjing Li; Hyun Jeong Kim; et al. "Role of POMC and AgRP neuronal activities on glycaemia in mice". Scientific Reports 9 1 (2019): https://doi.org/10.1038/s41598-019-49295-7.
    10.1038/s41598-019-49295-7
  9. Lee, Chan Hee; Kim, Hyo Jin; Lee, Yong-Soo; Kang, Gil Myoung; Lim, Hyo Sun; Lee, Seung-hwan; Song, Do Kyeong; et al. "Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation". Cell Reports 25 4 (2018): 934-946.e5. http://dx.doi.org/10.1016/j.celrep.2018.09.070.
    10.1016/j.celrep.2018.09.070
  10. Oh, Ah-Reum; Sohn, Seonyong; Lee, Junghoon; Park, Jong-Min; Nam, Ki Taek; Hahm, Ki-Baik; Kim, Young-Bum; Lee, Ho-Jae; Cha, Ji-Young. "ChREBP deficiency leads to diarrhea-predominant irritable bowel syndrome". Metabolism 85 (2018): 286-297. http://dx.doi.org/10.1016/j.metabol.2018.04.006.
    10.1016/j.metabol.2018.04.006
  11. Han, Ji Hye; Oh, Tae Jung; Lee, Ghayoung; Maeng, Hyo Jin; Lee, Dong Hwa; Kim, Kyoung Min; Choi, Sung Hee; et al. "The beneficial effects of empagliflozin, an SGLT2 inhibitor, on atherosclerosis in ApoE -/- mice fed a western diet". Diabetologia 60 2 (2016): 364-376. http://dx.doi.org/10.1007/s00125-016-4158-2.
    10.1007/s00125-016-4158-2
  12. Lim, Soo; Lee, Gha Young; Park, Ho Seon; Lee, Dong-Hwa; Tae Jung, Oh; Kyoung Min, Kim; Kim, Young-Bum; et al. "Attenuation of carotid neointimal formation after direct delivery of a recombinant adenovirus expressing glucagon-like peptide-1 in diabetic rats". Cardiovascular Research 113 2 (2016): 183-194. http://dx.doi.org/10.1093/cvr/cvw213.
    10.1093/cvr/cvw213
Edição de número de revista
  1. "Circulating ApoJ is closely associated with insulin resistance in human subjects". (2018):

Outros

Outra produção
  1. Rho-kinase mediates the anorexigenic action of melanocortin by suppressing AMPK. 2019. Sang Soo Kim; Won Min Hwang; Won-Mo Yang; Hyon Lee; Kyong Soo Park; Yossi Dagon; Young-Bum Kim. https://doi.org/10.1101/677880.
    10.1101/677880