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Mélanie Pruvost is a paleogenetician, specialized in the study of human and animal populations using ancient DNA. Coordinator of the ANR Ancestra project (2015-2020), she was particularly interested in the population of the territory that corresponds to present-day France from the Mesolithic to the High Middle Ages. She is also working on various projects in collaboration with other researchers to study the evolution of the genetic diversity of certain animal species under anthropogenic pressure, particularly during the process of domestication.
Identificação

Identificação pessoal

Nome completo
Melanie Pruvost

Nomes de citação

  • Pruvost, Melanie

Identificadores de autor

Ciência ID
481F-A760-D37E
ORCID iD
0000-0001-7824-2155

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Francês (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Projetos

Bolsa

Designação Financiadores
2015/12 - 2019/06 ANCESTRA, Genetic characterization of ancestral French populations using ancient DNA
ANR-15-CE27-0001
Investigador responsável
Agence nationale de la recherche
Concluído

Outro

Designação Financiadores
2021/04 - Atual Tracking the evolution of human craniodental structures – GenoMorph
ANR-20-CE12-0018
Investigador
Université de Bordeaux, França
Em curso
2019 - Atual GENETIX
LAbEx LaScArBx
Orientador
Em curso
2019 - Atual LANGPOP
Labex Archimede
Investigador
Produções

Publicações

Artigo em revista
  1. Mélanie Pruvost. "7000 years of the peopling of present-day France revealed by paleogenomics". TheScienceBreaker (2020): https://hal.archives-ouvertes.fr/hal-03093828.
    10.25250/thescbr.brk443
  2. Samantha Brunel; E. Andrew Bennett; Laurent Cardin; Damien Garraud; Hélène Barrand Emam; Alexandre Beylier; Bruno Boulestin; et al. "Ancient genomes from present-day France unveil 7,000 years of its demographic history". Proceedings of the National Academy of Sciences of the United States of America (2020): https://hal.archives-ouvertes.fr/hal-03039135.
    10.1073/pnas.1918034117
  3. Fages A; Hanghøj K; Khan N; Gaunitz C; Seguin-Orlando A; Leonardi M; McCrory Constantz C; et al. "Tracking Five Millennia of Horse Management with Extensive Ancient Genome Time Series.". Cell (2019): http://europepmc.org/abstract/med/31056281.
    10.1016/j.cell.2019.03.049
  4. Librado P; Gamba C; Gaunitz C; Der Sarkissian C; Pruvost M; Albrechtsen A; Fages A; et al. "Ancient genomic changes associated with domestication of the horse.". Science (New York, N.Y.) (2017): http://europepmc.org/abstract/med/28450643.
    10.1126/science.aam5298
  5. Bennett EA; Champlot S; Peters J; Arbuckle BS; Guimaraes S; Pruvost M; Bar-David S; et al. "Taming the late Quaternary phylogeography of the Eurasiatic wild ass through ancient and modern DNA.". PloS one (2017): http://europepmc.org/abstract/med/28422966.
    10.1371/journal.pone.0174216
  6. Cruz-Dávalos DI; Llamas B; Gaunitz C; Fages A; Gamba C; Soubrier J; Librado P; et al. "Experimental conditions improving in-solution target enrichment for ancient DNA.". Molecular ecology resources (2016): http://europepmc.org/abstract/med/27566552.
    10.1111/1755-0998.12595
  7. Guimaraes S; Pruvost M; Daligault J; Stoetzel E; Bennett EA; Côté NM; Nicolas V; et al. "A cost-effective high-throughput metabarcoding approach powerful enough to genotype ~44 000 year-old rodent remains from Northern Africa.". Molecular ecology resources (2016): http://europepmc.org/abstract/med/27374145.
    10.1111/1755-0998.12565
  8. Côté NM; Daligault J; Pruvost M; Bennett EA; Gorgé O; Guimaraes S; Capelli N; et al. "A New High-Throughput Approach to Genotype Ancient Human Gastrointestinal Parasites.". PloS one (2016): http://europepmc.org/abstract/med/26752051.
    10.1371/journal.pone.0146230
  9. Gorgé O; Bennett EA; Massilani D; Daligault J; Pruvost M; Geigl EM; Grange T. "Analysis of Ancient DNA in Microbial Ecology.". Methods in molecular biology (Clifton, N.J.) (2016): http://europepmc.org/abstract/med/26791510.
    10.1007/978-1-4939-3369-3_17
  10. Ludwig A; Reissmann M; Benecke N; Bellone R; Sandoval-Castellanos E; Cieslak M; Fortes GG; et al. "Twenty-five thousand years of fluctuating selection on leopard complex spotting and congenital night blindness in horses.". Philosophical transactions of the Royal Society of London. Series B, Biological sciences (2015): http://europepmc.org/abstract/med/25487337.
    10.1098/rstb.2013.0386
  11. Ludwig A; Pruvost M; Bellone R; Benecke N; Sandoval-Castellanos E; Morales-Muñiz A; O'Connor T; Reissmann M; Hofreiter M. "Reply to Bar-Oz and Lev-Yadun: Horse colors in time and space.". Proceedings of the National Academy of Sciences of the United States of America (2012): http://europepmc.org/abstract/PMC/PMC3356605.
    10.1073/pnas.1203187109
  12. Pruvost M; Bellone R; Benecke N; Sandoval-Castellanos E; Cieslak M; Kuznetsova T; Morales-Muñiz A; et al. "Genotypes of predomestic horses match phenotypes painted in Paleolithic works of cave art.". Proceedings of the National Academy of Sciences of the United States of America (2011): http://europepmc.org/abstract/med/22065780.
    10.1073/pnas.1108982108
  13. Pruvost M; Reissmann M; Benecke N; Ludwig A. "From genes to phenotypes - evaluation of two methods for the SNP analysis in archaeological remains: pyrosequencing and competitive allele specific PCR (KASPar).". Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft (2011): http://europepmc.org/abstract/med/22154270.
    10.1016/j.aanat.2011.10.007
  14. Cieslak M; Pruvost M; Benecke N; Hofreiter M; Morales A; Reissmann M; Ludwig A. "Origin and history of mitochondrial DNA lineages in domestic horses.". PloS one (2010): http://europepmc.org/abstract/med/21187961.
    10.1371/journal.pone.0015311
  15. Champlot S; Berthelot C; Pruvost M; Bennett EA; Grange T; Geigl EM. "An efficient multistrategy DNA decontamination procedure of PCR reagents for hypersensitive PCR applications.". PloS one (2010): http://europepmc.org/abstract/med/20927390.
    10.1371/journal.pone.0013042
  16. Ludwig A; Pruvost M; Reissmann M; Benecke N; Brockmann GA; Castaños P; Cieslak M; et al. "Coat color variation at the beginning of horse domestication.". Science (New York, N.Y.) (2009): http://europepmc.org/abstract/med/19390039.
    10.1126/science.1172750
  17. Mélanie Pruvost; Reinhard Schwarz; Virginia Bessa Correia; Sophie Champlot; Thierry Grange; Eva-Maria Geigl. "DNA diagenesis and palaeogenetic analysis : Critical assessment and methodological progress". Palaeogeography, Palaeoclimatology, Palaeoecology (2008): https://hal.archives-ouvertes.fr/hal-00326916.
    10.1016/j.palaeo.2008.03.041
  18. Mélanie Pruvost; Reinhard Schwarz; Virginia Bessa Correia; Sophie Champlot; Séverine Braguier; Nicolas Morel; Yolanda Fernandez-Jalvo; Thierry Grange; Eva-Maria Geigl. "Freshly excavated fossil bones are best for amplification of ancient DNA.". Proceedings of the National Academy of Sciences of the United States of America (2007): https://hal.archives-ouvertes.fr/hal-00124469.
    10.1073/pnas.0610257104
  19. Mélanie Pruvost; Thierry Grange; Eva-Maria Geigl. "Minimizing DNA contamination by using UNG-coupled quantitative real-time PCR on degraded DNA samples: application to ancient DNA studies.". Biotechniques (2005): https://hal.archives-ouvertes.fr/hal-00069259.
Relatório
  1. Muriel Gandelin; Frédéric Chandevau; Jean Guilaine; Christophe Ranché; Jean Vaquer; Caroline Hamon; Fabien Convertini; et al. 2018. Milieu et Peuplement en Languedoc occidental du Néolithique au Bronze ancien Occitanie, Projet collectif de Recherches. https://hal-univ-tlse2.archives-ouvertes.fr/hal-02025738.

Outros

Outra produção
  1. Taming the Late Quaternary phylogeography of the Eurasiatic wild ass through ancient and modern DNA. 2016. Bennett EA; Champlot S; Peters J; Arbuckle BS; Guimaraes S; Pruvost M; Bar-David S; et al. http://europepmc.org/abstract/PPR/PPR27155.
    10.1101/090928
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2019/10/03 Le projet Ancestra: Archéologie des migrations. L'hospitalité défiée par les migrations conférence du Chateau de Goutelas.
entre culturel de rencontre, Goutelas (França)
2019/01/23 De la couleur de la robe des chevaux à l'évolution des populations humaines: illustration des études phénotypiques basées sur l'ADN ancien .
Société d'Anthropologie de Paris (França)
2018/11/29 Qui sont les gens du début du Bronze final dans le sud-est du bassin parisien? Troisièmes Rencontres Nord-Sud de Préhistoire récente
(Lyon, França)
2018/11 Diversité génétique des populations néolithiques françaises : aperçu des premiers résultats du projet ANCESTRA. Morts néolithiques, Table ronde de l’Adreuc
(Carcassone, França)
2018/06/04 Paleogenomics of a French population, from the Neolithic to the Bronze Age. XVIII° CONGRES UISPP
(Paris, França)
2016/12/07 Ancient DNA bares its teeth : What ancient calculus can tell us about past populations? DNA POLYMORPHISMS IN HUMAN POPULATIONS
Musée de l'Homme (Paris, França)
2014/08/27 aMPlex-Torrent : a powerful and economical approach to study past-biodiversity.
The Fifth International Symposium on Biomolecular Archaeology, (Basel, Suiça)
2014/03/26 High-throughput studies of the past biodiversity. ICAZ working group
Faculdade de Ciências da Universidade de Lisboa (Lisboa, Portugal)
2010/09/08 Nuclear ancient DNA draws picture of wild and early domesticated horses. The Fourth International Symposium on Biomolecular Archaeology
(Copenhagen, Dinamarca)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2019 - Atual Migrations et fonctionnement des communautés de la transition Néolithique final-Âge du Bronze ancien en Europe de l’Ouest : apport de la Paléogénomique
Orientador
Université de Bordeaux, França
2017 - 2019 Study of the microbiome evolution on ancient human populations.
Orientador
Institute Jacques Monod, França
2014 - 2015 Hybridization-based target enrichment coupled to next generation sequencing to genotype ancient individuals
Orientador
 PhD (Doutoramento)
Institute Jacques Monod, França
2013 - 2014 Génotypage à Haut-Débit d’ossements humains anciens par PCR multiplex
Coorientador
Institute Jacques Monod, França
2007 - 2009 Coat colours and mitochondrial lineages of ancient horses to document domestication
Coorientador
Freie Universität Berlin Angewandte Genetik, Alemanha