Artigo em revista |
- Mariana Ferreira; Patrícia Carneiro; Vera Marisa Costa; Félix Carvalho; Andreas Meisel; João Paulo Capela; Ferreira, Mariana;
et al. "Amphetamine and methylphenidate potential on the recovery from stroke and traumatic brain injury: a review". Reviews
in the Neurosciences (2024): https://doi.org/10.1515/revneuro-2024-0016.
Submetido • 10.1515/revneuro-2024-0016
- Ana Reis-Mendes; Cláudia Vitorino-Oliveira; Mariana Ferreira; Félix Carvalho; Fernando Remião; Emília Sousa; Maria de Lourdes
Bastos; et al. Autor correspondente: Costa, Vera M. "Comparative In Vitro Study of the Cytotoxic Effects of Doxorubicin’s
Main Metabolites on Cardiac AC16 Cells Versus the Parent Drug". Cardiovascular Toxicology (2024): https://doi.org/10.1007/s12012-024-09829-6.
Aceite para publicação • 10.1007/s12012-024-09829-6
- Araújo, Ana Margarida; Marques, Sandra; Guedes de Pinho, Paula; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; Ana Margarida
Araújo; et al. Autor correspondente: Araújo, Ana Margarida. "Identification of key neuronal mechanisms triggered by dimethyl
fumarate in SH-SY5Y human neuroblastoma cells through a metabolomic approach". Archives of Toxicology (2024): https://doi.org/10.1007/s00204-024-03683-9.
Aceite para publicação • 10.1007/s00204-024-03683-9
- Carapito, Ângela; Roque, Ana Cecília A.; Carvalho, Félix; Pinto, Joana; Guedes de Pinho, Paula. "Exploiting volatile fingerprints
for bladder cancer diagnosis: A scoping review of metabolomics and sensor-based approaches". Talanta 268 (2024): 125296.
http://dx.doi.org/10.1016/j.talanta.2023.125296.
Publicado • 10.1016/j.talanta.2023.125296
- Proença, Carina; Maria Carolina Lobo; Ana T. Rufino; Ferreira de Oliveira, José Miguel P.; Freitas, Marisa; Jenifer Trepiana;
Maria P. Portillo; Carvalho, Félix; Eduarda Fernandes. Autor correspondente: Proença, Carina. "Evidence of phenolic compounds
as modulators of ChREBP and NRF2 in type 2 diabetes: a review of their potential for drug development". (2024):
Submetido
- Carneiro, Patrícia; Ferreira, Mariana; Costa, Vera Marisa; Carvalho, Félix; Capela, João Paulo. "Protective effects of amphetamine
and methylphenidate against dopaminergic neurotoxins in SH-SY5Y cells". Current Research in Toxicology (2024):
Submetido
- Vitorino-Oliveira, Cláudia; Kahremany, Shirin; Nisim, Leon; Duarte-Araújo , Margarida; Carvalho, Félix; Gruzman, Arie; Costa,
Vera Marisa. "Assessing the cytotoxic effects of sunitinib on AC16 cardiac cells and its potential association with autophagy".
(2024): https://doi.org/10.48797/sl.2024.133.
https://doi.org/10.48797/sl.2024.133
- Luís, Cláudia; Vitorino-Oliveira, Cláudia; Gaspar, Helena; Carvalho, Félix; Capela, João Paulo; Costa, Vera Marisa. "Comparing
Cytotoxic Effects of Synthetic Cathinones and Methamphetamine on Cardiac AC16 Cell". (2024): https://doi.org/10.48797/sl.2024.251.
https://doi.org/10.48797/sl.2024.251
- Soares-Couto, Patrícia; Costa, Vera Marisa; Dias-Carvalho, Ana; Sá, Susana Isabel; Ferreira, Mariana; Carvalho, Félix; Capela,
João Paulo. "Oral methylphenidate effects on GAP43 and PSD95 expression in the developing brains of Wistar Kyoto rats". (2024):
https://doi.org/10.48797/sl.2024.195.
https://doi.org/10.48797/sl.2024.195
- Barbosa-Azevedo, Maria; Cardoso, Maria; Carvalho, Félix; Costa, Vera M.. "Anticancer drugs and their impact on chemobrain
development: an in vitro investigation". (2024): https://doi.org/10.48797/sl.2024.241.
https://doi.org/10.48797/sl.2024.241
- Roque-Bravo, Rita; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Dias-da-Silva, Diana. "The effect of synthetic cannabinoid
ADB-FUBINACA on primary neuronal cultures ß-galactosidase activity: preliminary findings". (2024): https://doi.org/10.48797/sl.2024.135.
https://doi.org/10.48797/sl.2024.135
- Sousa, Adelaide; Azevedo, Rui; Costa, Vera M.; Oliveira, Sara; Viana, Sofia; Reis, Flávio; Almeida, Agostinho; et al. "Exploring
quercetin's potential to counteract intestinal pro-inflammatory effects induced by silver nanoparticles". (2024): https://doi.org/10.48797/sl.2024.240.
https://doi.org/10.48797/sl.2024.240
- Ramalho, Ana; Carvalho, Félix; Fernandes, Eduarda; Freitas, Marisa. "Unveiling the impact of parabens on human neutrophils
oxidative burst under hyperglycaemia conditions". (2024): https://doi.org/10.48797/sl.2024.197.
https://doi.org/10.48797/sl.2024.197
- Carapito, Ângela; Teixeira-Marques, Ana; Jerónimo, Carmen; Henrique, Rui; A. Roque, Ana Cecília; Carvalho, Félix; Pinto, Joana;
Guedes de Pinho, Paula. "Urinary volatile metabolomic biomarkers for detection of bladder cancer". (2024): https://doi.org/10.48797/sl.2024.130.
https://doi.org/10.48797/sl.2024.130
- Sofia Reis Brandão; Ana Reis-Mendes; Maria João Neuparth; Félix Carvalho; Rita Ferreira; Vera Marisa Costa. "The Metabolic
Fingerprint of Doxorubicin-Induced Cardiotoxicity in Male CD-1 Mice Fades Away with Time While Autophagy Increases". Pharmaceuticals
(2023): https://doi.org/10.3390/ph16111613.
10.3390/ph16111613
- Reis-Mendes, Ana; Ferreira, Mariana; Padrão, Ana Isabel; Duarte, José Alberto; Araújo, Ana Margarida; Remião, Fernando; Carvalho,
Félix; et al. Autor correspondente: Reis-Mendes, Ana. "The role of inflammation and antioxidant defenses in the cardiotoxicity
of doxorubicin in elderly CD-1 male mice". Archives of Toxicology 97 12 (2023): 3163-3177. https://link.springer.com/article/10.1007/s00204-023-03586-1#citeas.
Publicado • 10.1007/s00204-023-03586-1
- Rocha, Sílvia; Rufino, Ana T.; Freitas, Marisa; Silva, Artur M. S.; Carvalho, Félix; Fernandes, Eduarda. "Methodologies for
Assessing Pancreatic Lipase Catalytic Activity: A Review". Critical Reviews in Analytical Chemistry (2023): 1-28. http://dx.doi.org/10.1080/10408347.2023.2221731.
10.1080/10408347.2023.2221731
- Brandão, Sofia; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Neuparth, Maria; Rocha, Hugo; Carvalho, Félix; Ferreira, Rita;
et al. Autor correspondente: Costa, Vera M. "Cardiac Molecular Remodeling by Anticancer Drugs: Doxorubicin Affects More Metabolism
While Mitoxantrone Impacts More Autophagy in Adult CD-1 Male Mice". Biomolecules 13 6 (2023): 921. http://dx.doi.org/10.3390/biom13060921.
10.3390/biom13060921
- Costa, Vera M; Capela, João Paulo; Bastos, Maria Lourdes; Remião, Fernando; Varner, Kurt James; Duarte, José Alberto; Carvalho,
Félix; et al. Autor correspondente: Carvalho, Félix. "Study of the potential toxicity of adrenaline to neurons, using the
SH-SY5Y human cellular model". Brazilian Journal of Pharmaceutical Sciences 59 (2023): e20467. http://dx.doi.org/10.1590/s2175-97902023e20467.
Publicado • 10.1590/s2175-97902023e20467
- Sandra I. Marques; Helena Carmo; Félix Carvalho; Susana I. Sá; João Pedro Silva. "A Semi-Automatic Method for the Quantification
of Astrocyte Number and Branching in Bulk Immunohistochemistry Images". International Journal of Molecular Sciences
(2023): https://doi.org/10.3390/ijms24054508.
10.3390/ijms24054508
- Roque-Bravo, Rita; Silva, Rafaela Sofia; Malheiro, Rui F.; Carmo, Helena; Carvalho, Félix; da Silva, Diana Dias; Silva, João
Pedro; et al. "Synthetic Cannabinoids: A Pharmacological and Toxicological Overview". Annual Review of Pharmacology and
Toxicology 63 1 (2023): 187-209. http://dx.doi.org/10.1146/annurev-pharmtox-031122-113758.
10.1146/annurev-pharmtox-031122-113758
- Ana Reis-Mendes; Félix Carvalho; Fernando Remião; Emília Sousa; Maria de Lourdes Bastos; Vera Marisa Costa. "Autophagy (but
not metabolism) is a key event in mitoxantrone-induced cytotoxicity in differentiated AC16 cardiac cells". Archives of
Toxicology (2023): https://doi.org/10.1007/s00204-022-03363-6.
10.1007/s00204-022-03363-6
- Martins, Alexandra; da Silva, Diana Dias; Silva, Renata; Carvalho, Félix; Guilhermino, Lúcia. "Warmer water, high light intensity,
lithium and microplastics: Dangerous environmental combinations to zooplankton and Global Health?". Science of The Total
Environment 854 (2023): 158649. http://dx.doi.org/10.1016/j.scitotenv.2022.158649.
10.1016/j.scitotenv.2022.158649
- Malheiro, Rui Filipe; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; Malheiro, RF; Carmo, H; Carvalho, F; Silva, JP. "Cannabinoid-mediated
targeting of mitochondria on the modulation of mitochondrial function and dynamics". Pharmacological Research 187 (2023):
106603. http://dx.doi.org/10.1016/j.phrs.2022.106603.
Publicado • 10.1016/j.phrs.2022.106603
- Reis-Mendes, A.; Ferreira, M.; Padrão, A.I.; Duarte, J.A.; Duarte-Araújo, M.; Remião, F.; Carvalho, F.; et al. Autor correspondente:
Costa, Vera M. "The Role of Nrf2 and Inflammation on the Dissimilar Cardiotoxicity of Doxorubicin in Two-Time Points: a Cardio-Oncology
In Vivo Study Through Time". Inflammation (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85174019285&partnerID=MN8TOARS.
Aceite para publicação • 10.1007/s10753-023-01908-0
- Sousa, A.; Rufino, A.T.; Fernandes, R.; Malheiro, A.; Carvalho, F.; Fernandes, E.; Freitas, M.. "Silver nanoparticles exert
toxic effects in human monocytes and macrophages associated with the disruption of ¿¿m and release of pro-inflammatory cytokines".
Archives of Toxicology 97 2 (2023): 405-420. http://www.scopus.com/inward/record.url?eid=2-s2.0-85142511559&partnerID=MN8TOARS.
10.1007/s00204-022-03415-x
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- Sousa, A.; Azevedo, R.; Costa, V.M.; Oliveira, S.; Preguiça, I.; Viana, S.; Reis, F.; et al. "Biodistribution and intestinal
inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice". Archives of Toxicology
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10.1007/s00204-023-03558-5
- Silva, J.P.; Carvalho, F.. "Drugs of abuse and epigenetics: Past, present and future,Drogas de abuso y epigenética: Pasado,
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- Dias-Carvalho, Ana; Margarida-Araújo, Ana; Reis-Mendes, Ana; Sequeira, Catarina Oliveira; Pereira, Sofia Azeredo; Guedes de
Pinho, Paula; Carvalho, Félix; et al. Autor correspondente: Costa, Vera M. "A Clinically Relevant Dosage of Mitoxantrone Disrupts
the Glutathione and Lipid Metabolic Pathways of the CD-1 Mice Brain". International Journal of Molecular Sciences 24
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Publicado • https://doi.org/10.3390/ijms241713126
- Dinis-Oliveira, Ricardo Jorge; de Pinho, Paula Guedes; Santos, Liliana; Teixeira, Helena; Magalhães, Teresa; Santos, Agostinho;
de Lourdes Bastos, Maria; et al. "Postmortem analyses unveil the poor efficacy of decontamination, anti-inflammatory and immunosuppressive
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- Daniel José Barbosa; João Paulo Capela; Luísa Maria Ferreira; Paula Sério Branco; Eduarda Fernandes; Maria de Lourdes Bastos;
Félix Carvalho. "Ecstasy metabolites and monoamine neurotransmitters upshift the Na+/K+ ATPase activity in mouse brain synaptosomes".
Archives of Toxicology (2022): https://doi.org/10.1007/s00204-022-03370-7.
10.1007/s00204-022-03370-7
- Remião, Fernando; Carmo, Helena; Gomes, Miguel; Silva, Renata; Costa, Vera Marisa; Carvalho, Félix; Bastos, Maria de Lourdes;
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- Martins, Alexandra; da Silva, Diana Dias; Silva, Renata; Carvalho, Félix; Guilhermino, Lúcia. "Long-term effects of lithium
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- Brandão, Sofia Reis; Carvalho, Félix; Amado, Francisco; Ferreira, Rita; Costa, Vera M. Autor correspondente: Costa, Vera M.
"Insights on the molecular targets of cardiotoxicity induced by anticancer drugs: A systematic review based on proteomic findings".
Metabolism 134 (2022): 155250. http://dx.doi.org/10.1016/j.metabol.2022.155250.
Publicado • 10.1016/j.metabol.2022.155250
- Silva, João Pedro; Carvalho, Félix. "Therapeutical use of cannabis and cannabinoids: is there any scientific evidence? (INVITED,
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- Silva, João Pedro; Carmo, Helena; Carvalho, Félix. "Drugs of abuse and kidney toxicity (INVITED, CORRESPONDING/SENIOR AUTHOR).".
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Poster em conferência |
- Ana Ramalho; Carvalho, Félix; Eduarda Fernandes; Freitas, Marisa. "Unveiling the neutrophil response to parabens". Trabalho
apresentado em XVII Encontro Luso-Galego de Química, 2023.
- Inês Santos; Adelaide Sousa; Carvalho, Félix; Eduarda Fernandes; Freitas, Marisa. "In vitro effects of silver nanoparticles
and potential protective role of quercetin on the intestinal cell line C2BBe1". Trabalho apresentado em XVII Encontro Luso-Galego
de Química, 2023.
- Dias-Carvalho, Ana; Araújo, Ana Margarida; Reis-Mendes, A.; Sequeira, CO; Pereira, AS; Guedes de Pinho, Paula; Carvalho, Félix;
et al. "Chemobrain: exploring the impacto f a clinically relevant dose of mitoxantrone in the metabolic profile of CD-1 mice
brain". Trabalho apresentado em EMBO Young Scientists¿ Forum (Lisbon), 2023.
- Galipeau, Chloé; Miguel Farinha-Ferreira; Marques, Sandra; Silva, João Pedro; Mariani, JC; Diebolt, S; Barthe, L; et al. "The
role of 5-HT2AR activation in the long-lasting effects of psilocybin". Trabalho apresentado em European Molecular Biology
Organization (EMBO) Young Scientist Forum, 2023.
- Roque Bravo, Rita; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Dias da Silva, Diana. "Synthetic Cannabinoids and senescence
markersi n vitro: impact on cell proliferation, influence of cannabinoid receptors, and beta-galactosidase activity in SH-SY5Y
cells". Trabalho apresentado em 57th Congress of the European Societies of Toxicology (EUROTOX), 2023.
- Malheiro, RF; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. Autor correspondente: Silva, João Pedro. "THJ-2201, a synthetic
cannabinoid, modulates mitochondrial function and dynamics during the neurodifferentiation of NG108-15 cells at biologically
relevant concentrations". Trabalho apresentado em EUROTOX 2023, 2023.
- Silva, Rafaela; Barbosa, Daniel José; Carmo, Helena; Carvalho, Félix; da Silva, D. Dias; Silva, João Pedro. Autor correspondente:
Silva, João Pedro. "The impact of ADB-FUBINACA on the differentiation, maturation and astrocyte activation in in vitro primary
hippocampal cultures.". Trabalho apresentado em EUROTOX 2023, 2023.
- Pereira-Teixeira, C.; Almeida, Mariana; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. Autor correspondente: Silva, João
Pedro. "The synthetic cannabinoid ADB-FUBINACA decreases global DNA methylation during the neuronal differentiation of NG108-15
cells by increasing TET activity". Trabalho apresentado em EUROTOX 2023, 2023.
- Adelaide Sousa; Rui Azevedo; Costa, Vera M; Sara Oliveira; Inês Preguiça; Sofia Viana; Flávio Reis; et al. "Impact of dietary
exposure to silver nanoparticles on the intestinal inflammatory response in C57BL/6J mice". Trabalho apresentado em 12th
International Symposium on Biological Monitoring in Occupational and Environmental Health, 2023.
- Dias-da-Silva, Diana; Roque Bravo, Rita; Silva, João Pedro; Carmo, Helena; Carvalho, Félix. Autor correspondente: Dias-da-Silva,
Diana. "The synthetic cannabinoids ADB-FUBINACA and AMB-FUBINACA accelerate SH-SY5Y proliferation via stimulation of CB1 and
CB2 cannabinoid receptors". Trabalho apresentado em II TOXRUN International Congress, 2023.
- Valente, Maria João; Araújo, Ana Margarida; Carvalho, Félix; Carvalho, Márcia. "Toxicity of amphetamine-type drugs in rat
cardiomyocyte cells involves oxidative stress and the formation of acidic vesicular organelles". Trabalho apresentado em II
TOXRUN International Congress 2023 - No Boundaries for Toxicology: One Health, One Society, One Planet, 2023.
- Sandra Marques; Catarina Pereira-Teixeira ; Helena Carmo; Carvalho, Félix; João Pedro Silva; Marques, Sandra; Carmo, Helena;
Silva, João Pedro. "Pharmaceuticals associated with mood and cognitive adverse events promote epigenetic changes in human-induced
pluripotent stem cells-derived glutamatergic neurons at clinically-relevant concentrations". Trabalho apresentado em Society
of Toxicology - 62nd Annual Meeting & TOXEXPO, 2023.
- Maria Carolina Lobo; Proença, Carina; Rocha, Silvia; Rufino, Ana T.; Carvalho, Félix; Silva, Artur M. S.; Eduarda Fernandes.
"Flavonoids as potential anti-obesogenic agents through modulation of pancreatic lipase and protein tyrosine phosphatase 1B:
a structure-activity relationship". 2023.
- Araújo, Ana Margarida; Marques, Sandra; Pinho, Paula Guedes; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Application
of a GC-MS metabolomics approach to reveal how sub-toxic concentrations of ciprofloxacin affect the brain". Trabalho apresentado
em 12th National Meeting on Chromatography, 2022.
- Lobato-Freitas, Carolina; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; da Silva, Diana Dias. "The effects of Synthetic
Cannabinoids ADB-FUBINACA, AMB-FUBINACA, AB-CHMINACA and HU-308 on Differentiation and Proliferation of Brain NG108-15 Cells".
Trabalho apresentado em Lisbon Addictions 2022, 2022.
- da Silva, Diana Dias; Teixeira, Catarina; Garcia, Maria Rita; Roque-Bravo, Rita; Carmo, Helena; Carvalho, Félix; Silva, João
Pedro. "Crosstalk Between Autophagic Intermediaries in In Vitro Neurotoxicity Induced by Synthetic Cannabinoids". Trabalho
apresentado em Lisbon Addictions 2022, 2022.
- Telma M. Gomes; RF Malheiro; Mariana Almeida; Helena Carmo; Silva, João Pedro; Carvalho, Félix. "The synthetic cannabinoid
ADB-FUBINACA modulates epigenetic mechanisms during in vitro neuronal differentiation at biologically relevant concentrations".
Trabalho apresentado em Lisbon Addictions 2022, 2022.
- Marques, Sandra; Carmo, Helena; Carvalho, Félix; Sá, Susana I; Sá SI; Silva, João Pedro. "An improved IHC image post-processing
method for the semi-automatic quantification of astrocyte number and activation". Trabalho apresentado em 8th International
Electronic Conference on Medicinal Chemistry, 2022.
- Brandão, Sofia Reis; Filipa Reis-Mendes, Ana; Duarte-Araújo, M.; Rocha, Hugo; Neuparth, Maria João; Carvalho, Félix; Ferreira,
Rita; Costa, Vera M. "Cardiac metabolic adaptation after doxorubicin and mitoxantrone on adult mice". Trabalho apresentado
em 1st Conference of the Doctoral Program Metabolism ¿ Clinical and Experimental, The prism of Diabesity: looking by a
different perspective, 2022.
- Teixeira, Catarina; Garcia, Maria Rita; Roque-Bravo, Rita; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; da Silva, Diana
Dias. "Autophagic proteins ATG5, Beclin-1, Rab7A and LC3 are altered by Synthetic Cannabinoids in NG108-15 brain-derived cells".
Trabalho apresentado em 15th IJUP (Meeting of University of Porto¿s Young Researchers), 2022.
- Lobato-Freitas, Carolina; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; da Silva, Diana Dias. "Synthetic Cannabinoids
in Differentiation and Proliferation of NG108-15 Cells in vitro". Trabalho apresentado em 15th IJUP (Meeting of University
of Porto¿s Young Researchers), 2022.
- Maria Carolina Lobo; Sílvia Rocha; Freitas, Marisa; Carvalho, Félix; Artur M.S. Silva; Eduarda Fernandes; Ana T. Rufino.
"In vitro inhibitory activity of polyphenols against pancreatic lipase and a-amylase". Trabalho apresentado em IJUP¿15th
Meeting of Young Researchers of University of Porto, 2022.
- Maria Carolina Lobo; Rocha, S.; Carvalho, Félix; Silva, Artur; Fernandes, Eduarda; Rufino A.. "In vitro activity of polyphenols
against pancreatic lipase and a-amylase inhibition". Trabalho apresentado em IJUP - Young Researchers Meeting, 2022.
- Maria Carolina Lobo; Rocha, S.; Rufino A.; Carvalho, Félix; Silva, Artur; Fernandes, Eduarda. "Inhibition of Pancreatic Lipase
and a-Amylase by Polyphenols in In Vitro Microanalysis Systems". Trabalho apresentado em 14th Edition of the Nacional Organic
Chemistry Meeting and 7th Edition of the Nacional Therapeutic Chemistry Meeting, 2022.
- Ana T. Rufino; Ana Ramalho; Adelaide Sousa; José Miguel P. Ferreira de Oliveira; Paulo Freitas; Manuel A. Gonzalez Gómez;
Yolanda Piñeiro-Redondo; et al. Autor correspondente: Freitas, Marisa. "Evaluation of cytotoxic and pro-inflammatory effects
of silver nanoparticles: Potential protective effect of flavonoids". Trabalho apresentado em 14th National Organic Chemistry
Meeting & 7th National Medicinal Chemistry Meeting., 2022.
- Roque Bravo, Rita; Barbosa, Daniel José; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Dias da Silva, Diana. "SYNTHETIC
CANNABINOIDS AMB-FUBINACA, ADB-FUBINACA, AB-CHMINACA AND THJ-2201 IMPACT ON IN VITRO VIABILITY AND PROLIFERATION OF PRIMARY
RAT HIPPOCAMPAL NEURONS AND SH-SY5Y CELLS". Trabalho apresentado em I Congresso Internacional da TOXRUN; V Congresso Internacional
da Associação Portuguesa de Ciências Forenses, 2022.
- Araújo, Ana Margarida; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; Sandra Marques; Carmo, Helena; Maria Paula do Amaral
Alegria Guedes de Pinho; João Pedro Silva. "Can fluoroquinolones affect the brain? - A GC-MS metabolomics approach reveals
early neurotoxicity events triggered by ciprofloxacin". Trabalho apresentado em 61st Society of Toxicology (SOT) Annual
Meeting, 2022.
- Ferreira, Mariana; Dias-Carvalho, Ana; Reis-Mendes, Ana; Ferreira, Rita; Fernandes, Eduarda; Sá, Susana I; Sá SI; Capela,
João Paulo; Carvalho, Félix; Costa, Vera Marisa. "Evaluation of mitoxantrone neurotoxicity in CD-1 mice: A chemobrain study".
Trabalho apresentado em AIMS Meeting, 2022.
- Reis-Mendes, A.; Padrão, A.I.; Duarte-Araújo, M; Duarte, JA; Gonçalves-Monteiro, Salomé; Remião, Fernando; Carvalho, Félix;
et al. "Involvement of inflammation in DOX-induced cardiotoxicity: an in vivo study". Trabalho apresentado em 56th Congress
of the European Societies of Toxicology - Eurotox 2021, 2021.
- Dias-Carvalho, Ana; Ferreira, Mariana; Fernandes, Ana; Reis-Mendes, Ana; Araújo, Ana Margarida; Ferreira, Rita; Carvalho,
Félix; et al. "A neurotoxicidade de longo prazo da doxorrubicina no cérebro de ratinhos CD-1 adultos.". Trabalho apresentado
em 3º Encontro Nacional de Jovens Investigadores em Oncologia, Porto, Portugal, 2021.
- Malheiro, Rui; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "In vitro evaluation of the effects of the synthetic cannabinoids
ADB-FUBINACA and AMB-FUBINACA on mitochondrial function during neurodifferentiation. (SENIOR AUTHOR)". Trabalho apresentado
em EUROTOX2021 - 56th Virtual Congress of the European Societies of Toxicology, 2021.
- Marques, Sandra; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Varenicline increases histone H3 acetylation, while affecting
global DNA methylation on differentiated SH-SY5Y neuroblastoma cells. (SENIOR AUTHOR)". Trabalho apresentado em EUROTOX2021
¿ 56th Virtual Congress of the European Societies of Toxicology, 2021.
- Dias-Carvalho, Ana; Ferreira, Mariana; Fernandes, Ana; Reis-Mendes, Ana; Araújo, Ana Margarida; Ferreira, Rita; Carvalho,
Félix; et al. Autor correspondente: Dias-Carvalho, Ana. "The neurotoxicity of doxorubicin in the brain of adult CD-1 mice".
Trabalho apresentado em Ciência 2021 ¿ Science and Technology in Portugal Summit, Lisbon, Portugal, 2021.
- Malheiro, Rui; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "The synthetic cannabinoids ADB-FUBINACA and THJ-2201 affect
mitochondrial function during neuronal differentiation of NG108-15 cells at human-relevant concentrations. (SENIOR AUTHOR)".
Trabalho apresentado em Jornadas Ibéricas de Toxicologia (virtual meeting), 2021.
- Dias-Carvalho, Ana; Fernandes, Ana Olivía ; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Carvalho, Félix; Capela, João Paulo;
Sá, Susana Isabel; Costa, Vera Marisa. "Chemobrain: assessing the potential to recovery from doxorubicin-induced-neurotoxic
effects in CD-1 mice". Trabalho apresentado em 14º Encontro de Investigação Jovem da U. Porto (IJUP ¿21), 2021.
- Ferreira, Mariana; Dias-Carvalho, Ana; Reis-Mendes, Ana; Carvalho, Félix; Ferreira, Rita; Costa, Vera. "Evaluation of doxorubicin
and mitoxantrone neurotoxicity in CD-1 mice: A chemobrain study". Trabalho apresentado em 14th Meeting of young researches
of U. Porto (IJUP ¿21), 2021.
- Ferreira, Mariana; Dias-Carvalho, Ana; Reis-Mendes, Ana; Carvalho, Félix; Ferreira, Rita; Costa, Vera. "Doxorubicin and mitoxantrone
neurotoxicity in CD-1 mice: A chemobrain study". Trabalho apresentado em XII Biochemistry Day, 2021.
- Malheiro, Rui F.; Gomes, Telma M; Galani, M; Dias da Silva, Diana; Carmo, Helena; Carvalho, Félix; Silva, Joao Pedro; et al.
Autor correspondente: Silva, Joao Pedro. "ADB-FUBINACA, a synthetic cannabinoid, enhances in vitro neuronal differentiation
at biologically relevant concentrations". Trabalho apresentado em Society of Toxicology (SOT) Virtual Annual Meeting,
2021.
- Ana Dias Carvalho; Ana Reis-Mendes; Margarida Duarte-Araújo; Maria de Lourdes Bastos; Carvalho, Félix; Sá, Susana I; Sá SI;
Capela, João Paulo; Costa, Vera Marisa. "Chemobrain: evaluation of doxorubicin and mitoxantrone neurotoxicity in cd-1 mice".
Trabalho apresentado em SPF Meeting 2021 - Sociedade Portuguesa de Farmacologia, 2021.
- Dias-Carvalho, Ana; Ferreira, Mariana; Fernandes, Ana; Reis-Mendes, Ana; Araújo, Ana Margarida; Ferreira, Rita; Carvalho,
Félix; et al. Autor correspondente: Dias-Carvalho, Ana. "The long-term neurotoxicity of doxorubicin in the brain of adult
CD-1 mice". Trabalho apresentado em Congress of the European Societies of Toxicology (EUROTOX Congress 2021), 2021.
- Sá, Susana I; Sá SI; Ana Dias Carvalho; Ana Reis-Mendes; Margarida Duarte-Araújo; Carvalho, Félix; Maria de Lourdes Bastos;
Capela, João Paulo; Costa, Vera Marisa. "Evaluation of doxorubicin and mitoxantrone neurotoxicity in cd-1 mice". Trabalho
apresentado em SIFFUP - Simpósio de Investigação da FFUP, 2020.
- Araújo, Ana Margarida; Márcia Cláudia Dias de Carvalho; Costa, Vera Marisa; Duarte, José Alberto; Dinis-Oliveira, Ricardo
Jorge; Bastos, Maria de Lourdes; de Pinho, Paula Guedes; Carvalho, Félix. "Application of in vivo metabolomics to evaluate
the early pathways of toxicity triggered by human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV)". Trabalho apresentado
em 16th Annual Conference of Metabolomics Society - Metabolomics Online 2020, 2020.
- Carvalho, Ana Rita; Reis-Mendes, Ana; Duarte-Araujo, Margarida; Carvalho, Félix; Bastos, Maria de Lourdes; Capela, João Paulo;
Sá, Susana I; et al. "Neurotoxicidade da mitoxantrona e doxorrubicina: estudo in vivo em diferentes idades". Trabalho apresentado
em 2º Encontro Nacional de Jovens Investigadores em Oncologia, 2020.
- Rouxinol, Daniela; Dias da Silva, Diana; Silva, João Pedro; Bastos, Maria de Lourdes; Carvalho, Félix; Carmo, Helena. "Gas
Chromatography¿Mass Spectrometry (GC¿MS) for analysis of biodistribution and metabolic profile of 3,4-dimethylmethcathinone
(3,4- DMMC) in Wistar rats". Trabalho apresentado em 15th YES (Young European Scientist) Meeting ¿ Digital Experience,
2020.
- Dias-Carvalho, Ana; Fernandes, Ana Olivía ; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Carvalho, Félix; Capela, João Paulo;
Sá, Susana Isabel; Costa, Vera Marisa. "Doxorubicin Increases Apoptotic Markers in the hipocampal formation of CD-1 mice".
Trabalho apresentado em VI jornadas da Bioquímica: ¿O passaporte para a inovação¿, 2020.
- Ana Dias Carvalho; Ana Reis-Mendes; Margarida Duarte-Araújo; Carvalho, Félix; Sá, Susana I; Sá SI; Capela, João Paulo; Costa,
Vera Marisa; et al. "The effects of doxorubicin and mitoxantrone in mice brain at different aging stages: an in vivo chemobrain
study". Trabalho apresentado em SPF 2020 ¿ Reunião Anual da Sociedade Portuguesa de Farmacologia, 2020.
- Freitas, Marisa; Sousa, Adelaide; Soares, Tânia; Ribeiro, Daniela; Carvalho, Félix; Fernandes, Eduarda. "The role of calcium
in silver nanoparticles-induced human neutrophils¿ oxidative burst". Trabalho apresentado em SOT 59th Annual Meeting,
2020.
- Dias da Silva, Diana; Silva, João Pedro; Carmo, Helena; Bastos, Maria de Lourdes; Carvalho, Félix; Dias da Silva, Diana; Carvalho,
Félix; Silva, João Pedro. "Pharmacokinetics and pharmacodynamics of the synthetic cannabinoid UR-144 and its halogenated analogue
5F-UR-144 (XLR-11)". Trabalho apresentado em 3ª Conferência Europeia sobre Comportamentos e Dependências Aditivas subordinada
ao tema ¿The future of addictions ¿ new frontiers for policy, practice and science, 2019.
- Rouxinol, Daniela; Dias da Silva, Diana; Silva, João Pedro; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "Review:
the newly emerged designer psychostimulant 3,4-dimethylmethcathinone (3,4-DMMC)". Trabalho apresentado em 3ª Conferência
Europeia sobre Comportamentos e Dependências Aditivas subordinada ao tema ¿The future of addictions ¿ new frontiers for policy,
practice and science¿, 2019.
- Dias da Silva, Diana; Roque Bravo, Rita; Duarte de Almeida, Tomás; Valente, Maria João; Ferreira, Bárbara; Rebelo, RIta; Carvalho,
Félix; Bastos, Maria de Lourdes; Carmo, Helena. Autor correspondente: Dias da Silva, Diana. "The in vitro hepatotoxicity of
the new recreational drug 3-methylmethcathinone (3-MMC) involves autophagy and apoptosis". Trabalho apresentado em Lisbon
Addcitions 2019: 3rd European Conference on Addicted Behaviours and Dependencies, 2019.
- Roque Bravo, Rita; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Bastos, ML; Dias da Silva, Diaa. "Insights into benzo
fury toxicity: 5-(2-aminopropyl)benzofuran and 6-(2-aminopropyl)benzofuran disrupt oxidative, energetic and mitochondrial
homeostasis of hepatocytes in vitro.". Trabalho apresentado em Lisbon Addictions 2019, 2019.
- Rouxinol, D; Dias da Silva, Diana; Silva, João Pedro; Carvalho, Félix; Bastos, ML; Carmo, Helena. "The newly emerged designer
psychostimulant 3,4-dimethylmethcathinone (3,4-DMMC)". Trabalho apresentado em Lisbon Addictions 2019, 2019.
- Faria, Ana Carolina; Dias da Silva, Diana; Silva, João Pedro; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "Hyponatraemia
induced by synthetic phenethylamines.". Trabalho apresentado em The 3rd European Conference on Addictive Behaviours and
Dependencies (Lisbon Addictions 2019), 2019.
- Rodrigues, Daniela; Costa, Vera M; Bastos, Maria De Lourdes; Carvalho, Félix. "Effects of alpha-amanitin in HepG2 cells are
not prevented by drugs used in Amanita phalloides intoxications". Trabalho apresentado em EUROTOX 2019 - 55th Annual Meeting
of the Society of the European Toxicology Society, 2019.
- Araújo, Ana Margarida; Enea, Maria; Fernandes, Eduarda; Bastos, Maria de Lourdes; Carvalho, Félix; Guedes de Pinho, Paula;
Carvalho, Márcia. "A new strategy for exploring the role of hyperthermia in MDMA-induced toxicity in primary mouse hepatic
cells using GC-MS-based metabolomics". Trabalho apresentado em 55th European Congress of the European Societies of the
Toxicology (EUROTOX2019), 2019.
- Dionísio, Flávio; Duarte-Araújo, Margarida; de Lourdes Bastos, Maria; Carvalho, Félix; Costa, Vera Marisa. "The Main Metabolites
of Cyclophosphamide, 4-Hydroxycyclophosphamide and Acrolein, are Cardiotoxic at Relevant Clinical Concentrations". Trabalho
apresentado em 14th Young European Scientist Meeting, 2019.
- Faria, AC; Carmo, Helena; Teixeira, C; Rouxinol, D; Silva, João Pedro; Carvalho, Félix; Bastos, ML; et al. "Administration
of 3,4-dimethylmethcathinone (3,4-DMMC) and methylone increases the release of antidiuretic hormone in female Wistar rats".
Trabalho apresentado em EUROTOX2019, 2019.
- Rouxinol, D; Dias da Silva, Diana; Teixeira, C; Faria, AC; Silva, João Pedro; Carvalho, Félix; Bastos, ML; Carmo, Helena.
"Biodistribution of the new psychoactive stimulant 3,4-dimethylmethcathinone (3,4-DMMC) in Wistar rats assessed by gas chromatography-mass
spectrometry (GC-MS)". Trabalho apresentado em EUROTOX2019, 2019.
- Alexandre, JA; Malheiro, RM; Dias da Silva, Diana; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Synthetic cannabinoids
5F-PB22 and THJ-2201 promote in vitro CB1 receptor-dependent neuronal differentiation at in vivo-relevant concentrations.
(SENIOR AUTHOR)". Trabalho apresentado em EUROTOX2019, 2019.
- Carvalho, Ana Rita; Reis-Mendes, Ana Filipa; Duarte-Araujo, Margarida; Guedes, Rita; Gonçalves-Monteiro, Salomé; Carvalho,
Félix; Bastos, Maria de Lourdes; Capela, João Paulo; Costa, Vera M. "Doxorubicin and mitoxantrone effects on the brain of
differently aged mice: an in vivo chemobrain study". Trabalho apresentado em 55th Annual Meeting of the Society of the
European Toxicology Society - EUROTOX 2019, 2019.
- Araújo, Ana Margarida; Fernandes, Eduarda; Bastos, Maria de Lourdes; Carvalho, Félix; Guedes de Pinho, Paula; Carvalho, Márcia.
"Use of metabolomics for exploring early mechanisms of hepatotoxicity triggered by amphetamine-like drugs". Trabalho apresentado
em 15th Annual Conference of Metabolomics Society (Metabolomics 2019), 2019.
- Rodrigues, Daniela; Costa, Vera M; Bastos, Maria de Lourdes; Carvalho, Félix. "N-Acetylcysteine, silibinin and benzylpenicillin
do not confer protection against a-amanitin cytotoxicity in HepG2 and HepaRG cells". Trabalho apresentado em 58th Annual
Meeting of the Society of Toxicology, Baltimore, Maryland, EUA, 2019.
- Fernandes, Eduarda; Rufino, Ana; Ferreira de Oliveira, Miguel; Ribeiro, Daniela; Sousa, Adelaide; Soares, Tânia; Gónzalez-Gómez,
M.; et al. "Testing the Effects of Silver Nanoparticles in In Vitro Models of Intestinal Toxicity and Inflammation". Trabalho
apresentado em 10th International Conference ¿Biomaterials and Nanobiomaterials: Recent Advances Safety-Toxicology and
Ecological Issus¿, 2019.
- Roque Bravo, Rita; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "Toxicity of butylone,
buphedrone and 3,4-dimethylmethcathinone (3,4-DMMC) in in vitro hepatocyte models.". Trabalho apresentado em VII Annual
Meeting of the Portuguese Society for the Study of Abused and Neglected Children (SPECAN), IV Annual Meeting of the Portuguese
Association of Forensic Sciences (APCF) and Scientific Conferences of Sciences of the University Institute of Health,
2019.
- Teixeira, Catarina; Carmo, Helena; Rouxinol, Daniela; Faria, Ana Carolina; Carvalho, Félix; Bastos, Maria de Lourdes; Dias
da Silva, Diana. "3,4-DIMETHYLMETHCATHINONE (3,4-DMMC) AND METHYLONE AFFECT ENERGY LEVELS AND OXIDATIVE PARAMETERS IN DIFFERENT
ORGANS OF WISTAR RATS". Trabalho apresentado em IV Congresso da Associação Portuguesa de Ciências Forenses e XI Jornadas
Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, 2019.
- Rouxinol, Daniela; Dias da Silva, Diana; Teixeira, Catarina; Faria, Ana Carolina; Carvalho, Félix; Bastos, Maria de Lourdes;
Carmo, Helena. "GAS CHROMATOGRAPHY-MASS SPECTROMETRY (GC-MS) METHOD FOR THE ASSESSMENT OF THE BIODISTRIBUTION PROFILE OF THE
NEW PSYCHOSTIMULANT 3,4-DIMETHYLMETHCATHINONE (3,4-DMMC) IN WISTAR RATS". Trabalho apresentado em IV Congresso da Associação
Portuguesa de Ciências Forenses e XI Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências
da Saúde, 2019.
- Dias da Silva, Diana; Roque Bravo, Rita; Duarte de Almeida, Tomás; Valente, Maria João; Ferreira, Bárbara; Rebelo, Rita; Carvalho,
Félix; Bastos, Maria de Lourdes; Carmo, Helena. Autor correspondente: Dias da Silva, Diana. "Assessment of the potential hepatotoxicity
of the psychostimulant 3- methylmethcathinone (3-MMC), using primary rat hepatocytes". Trabalho apresentado em VII Annual
Meeting of the Portuguese Society for the Study of Abused and Neglected Children (SPECAN), IV Annual Meeting of the Portuguese
Association of Forensic Sciences (APCF) and Scientific Conferences of Sciences of the University Institute of Health,
2019.
- Faria, Ana Carolina; Carmo, Helena; Teixeira, Catarina; Rouxinol, Daniela; Carvalho, Félix; Bastos, Maria de Lourdes; Dias
da Silva, Diana. "Increased release of antidiuretic hormone (ADH) following administration of cathinone analogues in female
Wistar rats.". Trabalho apresentado em IV Congress of the Portuguese Association of Forensic Sciences, 2019.
- Ribeiro, Daniela; Freitas, Marisa; Carvalho, Félix; Fernandes, Eduarda (presenter). "The extended effects of thapsigargin
on human neutrophils¿ calcium pathways". Trabalho apresentado em SOT 58th Annual Meeting and ToxExpo, 2019.
10.1145/633292.633402
- Dias-Carvalho, Ana; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Guedes, Rita; Gonçalves-Monteiro, Salomé; Carvalho, Félix;
Bastos, Maria Lourdes; Capela, João Paulo; Costa, Vera Marisa. "Differential effects of doxorubicin and mitoxantrone in the
brain redox status of differently aged mice". Trabalho apresentado em 10th Annual International (bio)Medical Students Meeting,
2019.
- Costa, Vera M; Capela, João Paulo; Silveira, CM; Rodrigues, Patrícia; Eleutério, Rute; Dores-Sousa, José Luís; Carvalho, Rui
A; et al. "Mitoxantrone prompts early energetic and proteomic changes in HL-1 cardiomyocytes and late oxidative stress in
clinically relevant doses.". Trabalho apresentado em 58th Annual Meeting of the Society of Toxicology, Baltimore, Maryland,
EUA, 2019.
- Faria, Ana Carolina; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "Drug-induced hyponatraemia:
the case of synthetic cathinones.". Trabalho apresentado em 17th National Congress of Forensic Medicine and Forensic Sciences,
2018.
- Carvalho, Ana Rita; Reis-Mendes, Ana Filipa; Duarte-Araújo, Margarida; Guedes, Rita; Gonçalves-Monteiro, Salomé; Carvalho,
Félix; Bastos, Maria de Lourdes; Capela, João Paulo; Costa, Vera M. "The effects of doxorubicin and mitoxantrone in brain
glutathione levels of differently aged mice". Trabalho apresentado em Translational Research at iMed Conference® 10.0 |
Lisboa 2018, Lisboa, Portugal, 2018.
- Rocha-pereira, C.; Silva, Renata; Soares, Jorge; Casanova, Alfredo G.; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes;
Remião, Fernando. "TOX-OER MOOC: learning toxicokinetics and liver as target organ of xenobiotics.". Trabalho apresentado
em IPAP18 ¿ Salamanca. Innovation in Pharmacy: Advances and Perspectives. 24th ¿ 28th September 2018, Salamanca, Spain.,
2018.
- Pedro Nicola; Marisa Freitas; Sónia Rocha; Félix Carvalho; Eduarda Fernandes; Daniela Ribeiro; Eduarda das Graças Rodrigues
Fernandes; et al. "Optimization of a synaptosomal model to study the effect of carotenoids in the peroxynitrite - induced
lipid peroxidation". Trabalho apresentado em YES (Young European Scientist) Meeting, 2018.
- Araújo, Ana Margarida; Bastos, Maria de Lourdes; Fernandes, Eduarda; Carvalho, Félix; Carvalho, Márcia; Guedes de Pinho, Paula.
"Characterization of hepatic metabolic disturbances caused by subtoxic levels of 3,4-methylenedioxymethamphetamine (MDMA)".
Trabalho apresentado em UCIBIO Annual Meeting, 2018.
- Alexandre, JA; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; Parra, J; Araújo, ARTS. "Synthetic cannabinoids enhance
neuronal differentiation in neuroblastoma cells at in vivo relevant concentrations. (SENIOR AUTHOR)". Trabalho apresentado
em EUROTOX2018 ¿ 54th Congress of the European Societies of Toxicology, 2018.
- Reis-Mendes, Ana; Carvalho, Félix; Sousa, Emília; Bastos, Maria de Lourdes; Costa, Vera M. "Cardiotoxicity of FAC (5-Fluorouracil
+ Adriamycin + Cyclophosphamide) Metabolites in H9c2 Cardiac Differentiated Cells". Trabalho apresentado em 54th Congress
of European Societies of Toxicology, (Eurotox 2018) Brussels, Belgium, 2018.
- Soares, Jorge; Costa, Vera M; Bronze, Susana; Gaspar, Helena; Santos, Susana; Bastos, Maria De Lourdes; Carvalho, Félix; Capela,
João Paulo. "Neurotoxicity of synthetic cathinones and evaluation of putative neuroprotectors". Trabalho apresentado em Innovations
in Pharmacy. Advances & perspectives (IPAP18), Salamanca, Spain, 2018.
- Nicola, Pedro (presenter); Freitas, Marisa; Rocha, Sónia; Carvalho, Félix; Fernandes, Eduarda; Ribeiro, Daniela. "Synaptosomes
as lipid models to study the inhibition of peroxynitrite - induced lipid peroxidation". Trabalho apresentado em Italian
Spanish-Portuguese Joint Meeting in Medicinal Chemistry - MedChemSicily2018, 2018.
- Reis-Mendes, Ana; Carvalho, Félix; Sousa, Emília; Bastos, Maria de Lourdes; Costa, Vera M. "Main metabolites of 5-fluorouracil
+ adriamycin + cyclophosphamide (FAC) are not major contributors to FAC toxicity in H9c2 cardiac differentiated cells". Trabalho
apresentado em International Symposium - MitoPorto - mitochondrial evolution, metabolism and disease, Porto, Portugal,
2018.
- Eira, SG; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Role of cannabinoids in neuronal development. (SENIOR AUTHOR)".
Trabalho apresentado em Jornadas Científicas do Instituto Universitário de Ciências da Saúde (CESPU), 2018.
- Sousa, Daniela; Enea, Maria; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Guedes de Pinho, Paula; Dias da Silva,
Diana. "TOXICITY OF THE FAT BURNER 2,4-DINITROPHENOL (2,4-DNP) IN PRIMARY RAT HEPATOCYTES". Trabalho apresentado em XII
Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação
Portuguesa de Ciências Forenses (APCF), 2018.
- Ferreira, Bárbara; Dias da Silva, Diana; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "A REVIEW ON THE NOVEL
PSYCOACTIVE SUBSTANCE 3-METHYLMETHCATHINONE (3-MMC)". Trabalho apresentado em XII Jornadas Científicas de Ciências do Instituto
Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF),
2018.
- Faria, Ana Carolina; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "HYPONATRAEMIA INDUCED
BY SYNTHETIC CATHINONES". Trabalho apresentado em XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências
da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
- Rouxinol, Daniela; Dias da Silva, Diana; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "INTRACELLULAR MECHANISMS
UNDERLYING THE TOXICITY OF SYNTHETIC CATHINONES". Trabalho apresentado em XII Jornadas Científicas de Ciências do Instituto
Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF),
2018.
- Silva, Sara; Enea, Maria; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena; Dias da Silva, Diana. "HYPERTHERMIA EXACERBATES
THE CARDIOTOXICITY OF BENZYLPIPERAZINE (BZP) AND METHYLENEDIOXYMETHAMPHETAMINE (MDMA) COMBINATIONS IN H9C2 CELLS". Trabalho
apresentado em XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III
Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
- Martins, Maria João; Roque Bravo, Rita; Enea, Maria; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dinis-Oliveira,
Ricardo Jorge; Dias da Silva, Diana. "COCAINE AND ETHANOL ADDITIVELY IMPAIR OXIDATIVE, ENERGETIC AND MITOCHONDRIAL HOMEOSTASIS
IN H9C2 CARDIOMYOCYTES". Trabalho apresentado em XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências
da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
- Faria, Ana Carolina; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "Hyponatraemia: a potential
life threatening consequence of cathinones abuse.". Trabalho apresentado em III Congress of the Portuguese Association
of Forensic Sciences, 2018.
- Roque Bravo, Rita; Moreira, Patricia; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "4-Fluoromethamphetamine
exerts toxicity to hepatocellular in vitro models via CYP450-mediated metabolism.". Trabalho apresentado em VI Annual Meeting
of the Portuguese Society for the Study of Abused and Neglected Children (SPECAN), III Annual Meeting of the Portuguese Association
of Forensic Sciences (APCF) and Scientific Conferences of Sciences of the University Institute of Health, 2018.
- Alves, Marisa; Reis-Mendes, Ana; Carvalho, Félix; Remião, Fernando; Bastos, Maria Bastos; Costa, Vera M. "An in vitro study
with differentiated and non-differentiated H9c2 cells to evaluate pixantrone cardiotoxicity". Trabalho apresentado em 11st
Meeting of young researchers of University Porto (IJUP ¿18), Porto, Portugal, 2018.
- Loureiro, Sara; Costa, Vera M; Duarte, José Alberto; Duarte-Araújo, Margarida; Gonçalves-Monteiro, Salomé; Bastos, Maria de
Lourdes; Carvalho, Félix; Capela, João Paulo. "Methylphenidate evokes heart and kidney toxicity in adolescent rats exposed
one-week to relevant oral doses". Trabalho apresentado em Lisbon Addictions 2017, Lisboa, Portugal, 2017.
- Martins, Maria João; Moreira, Patricia; Roque Bravo, Rita; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dinis-Oliveira,
Ricardo Jorge; Dias da Silva, Diana. "Oxidative damage and energetic crisis in cardiomyocytes after co-exposure of cocaine
and morphine". Trabalho apresentado em LIII Congress of the European Toxicology Society (EUROTOX), 2017.
- Faria, Juliana; Barbosa, Joana; Leal, S; Afonso, L. P.; Lobo, J.; Moreira, Roxana; Queiros, Odilia; Carvalho, Félix; Dinis-Oliveira,
Ricardo Jorge. "Tramadol and tapentadol cause brain, lung and heart toxicity in effective and maximum tolerated doses". Trabalho
apresentado em EUROTOX Congress, 2017.
- Barbosa, Joana; Faria, Juliana; Leal, S; Afonso, L. P.; Lobo, J.; Moreira, Roxana; Queiros, Odilia; Carvalho, Félix; Dinis-Oliveira,
Ricardo Jorge. "Acute administration of tramadol and tapentadol induces dose-dependent hepato and nephrotoxicity in wistar
rats". Trabalho apresentado em EUROTOX Congress, 2017.
- Araújo, Ana Margarida; Lima, Ana Rita; Bastos, Maria de Lourdes; Carvalho, Félix; Carvalho, Márcia; Guedes de Pinho, Paula.
"Effect of subtoxic and toxic concentrations of galactosamina in the metabolome of primary mouse hepatocytes". Trabalho apresentado
em 53rd European Congress of the European Societies of the Toxicology (EUROTOX2017), 2017.
- Bárbara Ferreira; Rebelo, Rita; Patrícia Moreira; Carvalho, Félix; Diana Dias da Silva; Carmo, Helena. "Cytotoxicity of 3-methylmethcathinone
(3-MMC or metaphedrone) in primary rat hepatocytes." Poster communication presented by Bárbara Ferreira at II Congress of
Portuguese Association of Forensic Sciences, Porto, Portugal. March 30th-31st, 2017.". Trabalho apresentado em II Congress
of Portuguese Association of Forensic Sciences, 2017.
- Roque Bravo, Rita; Moreira, Patricia; Martins, Maria João; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena; Dias
da Silva, Diana. Autor correspondente: Roque Bravo, Rita. "In vitro hepatotoxicity of two new psychoactive benzofurans (5-APB
and 6-APB) used as recreational drugs". Trabalho apresentado em VI Annual Meeting of the Portuguese Society for the Study
of Abused and Neglected Children (SPECAN), III Annual Meeting of the Portuguese Association of Forensic Sciences (APCF) and
Scientific Conferences of Sciences of the University Institute of Health, 2017.
- Martins, Maria João; Moreira, Patricia; Roque Bravo, Rita; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dinis-Oliveira,
Ricardo Jorge; Dias da Silva, Diana. "Ethanol additively enhanced cardiotoxicity of cocaine in vitro through oxidative damage
and energetic deregulation.". Trabalho apresentado em V Annual Meeting of the Portuguese Society for the Study of Abused
and Neglected Children (SPECAN), III Annual Meeting of the Portuguese Association of Forensic Sciences (APCF) and Scientific
Conferences of Sciences of the University Institute of Health S, 2017.
- Pinho, Rita; Almeida, Daniela; Soares, Jorge; Bastos, Maria de Lourdes; Carvalho, Félix; Capela, João Paulo; Costa, Vera M.
"Mitoxantrone was more neurotoxic than doxorubicin in SH-5YSY human cells". Trabalho apresentado em 10th Meeting of young
researchers of University Porto (IJUP ¿17), Porto, Portugal, 2017.
- Valente, Maria João; Araújo, Ana Margarida; Silva, Renata; Amaral, Cristina; Silva, Georgina; Duarte, José Alberto; Fernandes,
Eduarda; et al. "In vitro toxicity of ß-keto amphetamines mechanistic studies in hepatic and neuronal cell models". Trabalho
apresentado em UCIBIO Advisory Board Member, 2017.
- Ferreira, Bárbara; Dias-da-Silva, Diana; Rebelo, Rita; Moreira, Patricia; Carvalho, Félix; Bastos, Maria Lurdes; Carmo, Helena;
et al. "Citotoxicity of 3-methylmethcathinone (3-MMC or metaphedrone) in primary rat hepatocytes". Trabalho apresentado em
II Congresso da Associação Portuguesa de Ciências Forenses e as Jornadas Científicas do Departamento de Ciências do Instituto
Universitário de Ciências da Saúde, Porto, Portugal, 2017.
- Roque Bravo, Rita; Martins, Maria João; Pinto, Ana Cristina; Valente, Maria João; Carvalho, Félix; Bastos, Maria da Lourdes;
Carmo, Helena; Dias da Silva, Diana. "Emerging club drugs: in vitro hepatotoxicity of six synthetic cathinones and benzofurans".
Trabalho apresentado em LIII Congress of the European Toxicology Society (EUROTOX), 2016.
- Neves, João; Soares, José; Alves, Emanuele; Cravo, Sara; Silva, Artur; Afonso, Carlos; Netto, Aníbal; Carvalho, Félix; Dinis-Oliveira,
Ricardo. "The homemade drug "Krokodil": chromatographic and spectroscopy studies". Trabalho apresentado em IJUP 2016,
2016.
- Valente, Maria João; Bastos, Maria de Lourdes; Carvalho, Félix; Guedes de Pinho, Paula; Carvalho, Márcia. "ßk-amphetamines:
neurotoxicity triggered by methylone and MDPV in undifferentiated and differentiated SH-SY5Y cells and comparison to MDMA".
Trabalho apresentado em 52nd European Congress of the European Societies of the Toxicology (EUROTOX 2016), 2016.
- Valente, Maria João; Araújo, Ana Margarida; Bastos, Maria de Lourdes; Fernandes, Eduarda; Carvalho, Félix; Guedes de Pinho,
Paula; Carvalho, Márcia. "Characterization of hepatotoxicity mechanisms triggered by synthetic cathinones". Trabalho apresentado
em UCIBIO - Encontro CIÊNCIA 2016, 2016.
- Bastos, Maria de Lourdes; Valente, Maria João; Araújo, Ana Margarida; Carvalho, Félix; Guedes de Pinho, Paula; Carvalho, Márcia.
"Synthetic cathinones: Unveiling the mechanisms for liver injury". Trabalho apresentado em Society of Toxicology¿s 55th
Annual Meeting, New Orleans, Louisiana, USA, 2016.
- Moreira, Patricia; Cunha, Sara; Dias-da-Silva, Diana; Carvalho, Félix; Basto, Maria Lurdes; Carmo, Helena. "Development and
validation of a method for the simultaneous determination of two piperazines used as drugs of abuse". Trabalho apresentado
em EUROTOX2016, Seville, Spain, 2016.
- Dias-da-Silva, Diana; Moreira, Patricia; Silva, Maria João; Carvalho, Félix; Bastos, Maria Lurdes; Carmo, Helena. "In vitro
hepatotoxicity of mixtures of benzylpiperazine (BZP) and 3-trifluoromethylphenylpiperazine (TFMPP)". Trabalho apresentado
em SOT Annual Meeting - Society of Toxicology, New Orleans, USA, 2016.
- Reis-Mendes, Ana; Gomes, Ana Sara; Carvalho, R.A.; Remião, Fernando; Carvalho, Félix; Pinto, Madalena; Bastos, Maria de Lourdes;
Sousa, Emília; Costa, Vera. "The cardiotoxicity of mitoxantrone: A comparative in vitro study between mitoxantrone and its
naphthoquinoxaline metabolite". Trabalho apresentado em IJUP¿15 ¿ 8th Meeting of Your Researchers of the University of
Porto, 2015.
- Bastos, Maria de Lourdes; Valente, Maria João; Araújo, Ana Margarida; Carvalho, Félix; Guedes de Pinho, Paula; Carvalho, Márcia.
"Hyperthermia exacerbates MDPV-induced hepatic oxidative stress". Trabalho apresentado em Society of Toxicology¿s 54th
Annual Meeting, San Diego, California, USA, 2015.
- Alves, Emanuele; Ferreira, Ana Sofia Agonia; Neves, João; Soares, José; Cravo, Sara; Afonso, Carlos; Netto, Aníbal; Carvalho,
Félix; Dinis, Ricardo. "Synthesis of the ¿Krokodil¿ drug through ¿street¿ reported methods, and product analysis.". Trabalho
apresentado em 53 rd The International Association of Forensic Toxicologists (TIAFT), Florence, Italy., 2015.
- Viana SD; Valero, Jorge; Rodrigues-Santos, Paulo; Couceiro, Patrícia; Silva, Andréa M.; Carvalho, Félix; Ali, Syed F.; Fontes
Ribeiro, C.A.; Pereira, F.C.. "EnRAGEd pre-gliotic striatal astrocytes in MPTP mice". Trabalho apresentado em VII Annual
Meeting of IBILI ¿New trends in biomedical research¿, 2015.
- Alves, Emanuele; Soares, José; Ferreira, AS; Cravo, Sara; Afonso, Carlos; Netto, Aníbal; Carvalho, Félix; Dinis-Oliveira,
Ricardo Jorge. "The chemistry behind ¿krokodil¿: street-like synthesis and product analysis". Trabalho apresentado em 4º
Encontro de Doutorandos da FMUP, 2014.
- Alves, Emanuele; Soares, José; Ferreira, AS; Afonso, Carlos; Netto, Aníbal; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge.
"A síntese ilícita de krokodil.". Trabalho apresentado em 1ª Conferência do Instituto Nacional de Medicina Legal e Ciências
Forenses, 2014.
- Alves, Emanuele; Agonia, A.; Cravo, Sara; Afonso, Carlos; Netto, Aníbal; Bastos, Maria de Lurdes; Carvalho, Félix; Dinis-Oliveira,
Ricardo Jorge. "Quantificação de opioides em sangue por Cromatografia Gasosa Acoplada a Espetrometria de Massa usando QuEChERS".
Trabalho apresentado em 1ª Conferência do Instituto Nacional de Medicina Legal e Ciências Forenses, 2014.
- Araújo, Ana Margarida; Valente, Maria João; Dias da Silva, Diana; Carvalho, Márcia; Gaspar, Helena; Carvalho, Félix; Bastos,
Maria de Lourdes; Guedes de Pinho, Paula. "Potential hepatotoxicity caused by synthetic cathinones acquired in ¿smartshops¿".
Trabalho apresentado em IJUP¿2014 - 7º Encontro de Jovens Investigadores da U.PORTO, 2014.
- Viana SD; Fernandes, Rosa C.; Canas, Paula M.; Silva, Andréa M.; Camila Portugal; Renato Socodato; Carvalho, Félix; et al.
"Unaltered S100B/RAGE axis in dysfunctional striata from MPTP-treated mice.". Trabalho apresentado em XVIII Congresso da
Sociedade Portuguesa de Bioquímica, 2014.
- Viana SD; Fernandes, Rosa C.; Canas, Paula M.; Silva, Andréa M.; Camila Portugal; Renato Socodato; Carvalho, Félix; et al.
"The quiet neuronal RAGE in a storming dysfunctional striata under a chronic MPTP challenge". Trabalho apresentado em 6th
Annual meeting of IBILI, 2014.
- Freitas, Marisa (presenter); Costa, V.M.; Ribeiro, Daniela; Couto, Diana; Porto, G.; Carvalho, Félix; Fernandes, Eduarda.
"Acetaminophen prevents oxidative burst and delays apoptosis in human neutrophils in vitro". Trabalho apresentado em 2nd
International Conference on Ocupacional and Environmental Toxicology 2013, 2013.
- Araújo, Ana Margarida; Bastos, Maria de Lourdes; Carvalho, Márcia; Carvalho, Félix; Gaspar, Helena; Cardoso Matias, Ana; Guedes
de Pinho, Paula. "Chemical characterization of ¿legal highs¿ marketed in Portuguese ¿smartshops¿". Trabalho apresentado em
12th National Congress of Legal Medicine and Forensic Sciences, 2013.
- Vale, Luís; Valente, Maria João; Carvalho, Jorge; Almeida, Liliana; Afonso, Joana; Morato, Manuela; Carvalho, Félix; et al.
"Low-dose acetylsalicylic acid improves the antihypertensive efficacy of losartan in spontaneously hypertensive rats". Trabalho
apresentado em Trabalho apresentado em IJUP 2013 - 6º Encontro de Jovens Investigadores da U.PORTO, 2013.
- Barbosa, Daniel José; Capela, João Paulo; Silva, Renata; Ferreira, Luísa Maria ; Branco, Paula Sério; Fernandes, Eduarda;
Bastos, Maria de Lourdes; Carvalho, Félix. "The mixture of "Ecstasy" and its metabolites, at low concentrations, is toxic
to SH-SY5Y differentiated cells". Trabalho apresentado em 48th Congress of the European Societies of Toxicology (EUROTOX),
2012.
- Reina-Couto, Marta; Sousa, Teresa; Morato, Manuela; Carvalho, Jorge; Marques, Marco; Morgado, Luís; Valente, Maria João; et
al. "Evaluation of oxidative stress markers in chronic heart failure". Trabalho apresentado em Trabalho apresentado em
IJUP 2012 - 5º Encontro de Jovens Investigadores da U.PORTO, 2012.
- Sousa, Teresa; Afonso, Joana; Valente, Maria João; Carvalho, Jorge; Serrão, Maria Paula; Morato, Manuela; Patinha, Daniela;
et al. "Hydrogen peroxide regulates renal production of renin and angiotensinogen in angiotensin II-hypertensive rats". Trabalho
apresentado em 22nd European Meeting on Hypertension and Cardiovascular Prevention, 2012.
- Vieira, David; Gomes, Ana Sara; Sousa, Emília; Afonso, Carlos; Pinto, Madalena; Carvalho, Félix; Santos-Silva, Alice; et al.
"Potential mutagenicity of TXA1, a small molecule potent inhibitor of tumor cell growth". Trabalho apresentado em Young
European Scientist Meeting Guide: YES Meeting, 2010.
- Dinis-Oliveira, Ricardo Jorge; Pinho, Paula Guedes; Magalhães, T.; Afonso, Carlos; Remião, Fernando; Bastos, Maria de Lurdes;
Carvalho, Félix. "Human postmortem histopathological and toxicokinetic analysis following paraquat intoxications, indicate
that traditional therapeutic measures, to eliminate paraquat and to prevent inflammation, need to be refined". Trabalho apresentado
em XXI Congress of the International Academy if Legal Medicine, Lisbon, 2009.
- Nunes, Carla; Sousa, Teresa; Fernandes, Eduarda; Carvalho, Félix; Laranjinha, João; Albino-Teixeira, António. "Direct scavenging
of nitric oxide by DPSPX (1,3-dipropyl-8-sulfophenilxantine)". Trabalho apresentado em Autumn meeting of the British Pharmacological
Society & the Physiological Society with Sociedade Portuguesa de Farmacologia, 2001.
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