Artigo em revista |
- Permana AD; Mir M; Utomo E; Donnelly RF. "Bacterially sensitive nanoparticle-based dissolving microneedles of doxycycline
for enhanced treatment of bacterial biofilm skin infection: A proof of concept study.". International journal of pharmaceutics:
X (2020): http://europepmc.org/abstract/med/32322819.
10.1016/j.ijpx.2020.100047
- Álvaro Cárcamo-Martínez; Juan Domínguez-Robles; Brónach Mallon; Md. Taifur Raman; Ana Sara Cordeiro; Steven E. J. Bell;
Eneko Larrañeta; Ryan F. Donnelly. "Potential of Polymeric Films Loaded with Gold Nanorods for Local Hyperthermia Applications".
Nanomaterials (2020): https://www.mdpi.com/2079-4991/10/3/582.
10.3390/nano10030582
- Ukrit Angkawinitwong; Aaron J. Courtenay; Aoife M. Rodgers; Eneko Larrañeta; Helen O. McCarthy; Steve Brocchini; Ryan F. Donnelly;
Gareth R. Williams. "A Novel Transdermal Protein Delivery Strategy via Electrohydrodynamic Coating of PLGA Microparticles
onto Microneedles". ACS Applied Materials & Interfaces 12 11 (2020): 12478-12488. https://doi.org/10.1021%2Facsami.9b22425.
10.1021/acsami.9b22425
- Stewart SA; Domínguez-Robles J; McIlorum VJ; Mancuso E; Lamprou DA; Donnelly RF; Larrañeta E. "Development of a Biodegradable
Subcutaneous Implant for Prolonged Drug Delivery Using 3D Printing.". Pharmaceutics (2020): http://europepmc.org/abstract/med/32013052.
10.3390/pharmaceutics12020105
- Vora, L.K.; Courtenay, A.J.; Tekko, I.A.; Larrañeta, E.; Donnelly, R.F.. "Pullulan-based dissolving microneedle arrays for
enhanced transdermal delivery of small and large biomolecules". International Journal of Biological Macromolecules
146 (2020): 290-298. http://www.scopus.com/inward/record.url?eid=2-s2.0-85077643830&partnerID=MN8TOARS.
10.1016/j.ijbiomac.2019.12.184
- Mir, M.; Permana, A.D.; Ahmed, N.; Khan, G.M.; Rehman, A.U.; Donnelly, R.F.. "Enhancement in site-specific delivery of carvacrol
for potential treatment of infected wounds using infection responsive nanoparticles loaded into dissolving microneedles: A
proof of concept study". European Journal of Pharmaceutics and Biopharmaceutics 147 (2020): 57-68. http://www.scopus.com/inward/record.url?eid=2-s2.0-85077335374&partnerID=MN8TOARS.
10.1016/j.ejpb.2019.12.008
- Permana, A.D.; Utami, R.N.; Courtenay, A.J.; Manggau, M.A.; Donnelly, R.F.; Rahman, L.. "Phytosomal nanocarriers as platforms
for improved delivery of natural antioxidant and photoprotective compounds in propolis: An approach for enhanced both dissolution
behaviour in biorelevant media and skin retention profiles". Journal of Photochemistry and Photobiology B: Biology
205 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85081022596&partnerID=MN8TOARS.
10.1016/j.jphotobiol.2020.111846
- Kelly, S.A.; Rodgers, A.M.; O'Brien, S.C.; Donnelly, R.F.; Gilmore, B.F.. "Gut Check Time: Antibiotic Delivery Strategies
to Reduce Antimicrobial Resistance". Trends in Biotechnology 38 4 (2020): 447-462. http://www.scopus.com/inward/record.url?eid=2-s2.0-85075834563&partnerID=MN8TOARS.
10.1016/j.tibtech.2019.10.008
- Uddin, M.J.; Scoutaris, N.; Economidou, S.N.; Giraud, C.; Chowdhry, B.Z.; Donnelly, R.F.; Douroumis, D.. "3D printed microneedles
for anticancer therapy of skin tumours". Materials Science and Engineering C 107 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85074346744&partnerID=MN8TOARS.
10.1016/j.msec.2019.110248
- Courtenay, A.J.; McAlister, E.; McCrudden, M.T.C.; Vora, L.; Steiner, L.; Levin, G.; Levy-Nissenbaum, E.; et al. "Hydrogel-forming
microneedle arrays as a therapeutic option for transdermal esketamine delivery". Journal of Controlled Release 322
(2020): 177-186. http://www.scopus.com/inward/record.url?eid=2-s2.0-85082117926&partnerID=MN8TOARS.
10.1016/j.jconrel.2020.03.026
- Al-Kasasbeh, R.; Brady, A.J.; Courtenay, A.J.; Larrañeta, E.; McCrudden, M.T.C.; O’Kane, D.; Liggett, S.; Donnelly, R.F..
"Evaluation of the clinical impact of repeat application of hydrogel-forming microneedle array patches". Drug Delivery
and Translational Research (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85081015634&partnerID=MN8TOARS.
10.1007/s13346-020-00727-2
- John Moohan; Sarah A. Stewart; Eduardo Espinosa Victor; Antonio Rosal; Alejandro; Eneko Larrañeta; Ryan F. Donnelly; Juan
Domínguez-Robles. "Cellulose Nanofibers and Other Biopolymers for Biomedical Applications. A Review". Applied Sciences
(2019): https://www.mdpi.com/2076-3417/10/1/65.
10.3390/app10010065
- Maria Mir; Naveed Ahmed; Andi Dian Permana; Aoife Maria Rodgers; Ryan F. Donnelly; Asim.ur. Rehman. "Enhancement in Site-Specific
Delivery of Carvacrol against Methicillin Resistant Staphylococcus aureus Induced Skin Infections Using Enzyme Responsive
Nanoparticles: A Proof of Concept Study". Pharmaceutics (2019): https://www.mdpi.com/1999-4923/11/11/606.
10.3390/pharmaceutics11110606
- Mary-Carmel Kearney; Peter E. McKenna; Helen L. Quinn; Aaron Courtenay; Eneko Larrañeta; Ryan F. Donnelly. "Design and Development
of Liquid Drug Reservoirs for Microneedle Delivery of Poorly Soluble Drug Molecules". Pharmaceutics (2019): https://www.mdpi.com/1999-4923/11/11/605.
10.3390/pharmaceutics11110605
- Rodgers AM; McCrudden MTC; Courtenay AJ; Kearney MC; Edwards KL; Ingram RJ; Bengoechea J; Donnelly RF. "Control of Klebsiella
pneumoniae Infection in Mice by Using Dissolving Microarray Patches Containing Gentamicin.". Antimicrobial agents and chemotherapy
(2019): http://europepmc.org/abstract/med/30858214.
10.1128/AAC.02612-18
- Domínguez-Robles J; Martin NK; Fong ML; Stewart SA; Irwin NJ; Rial-Hermida MI; Donnelly RF; Larrañeta E. "Antioxidant PLA
Composites Containing Lignin for 3D Printing Applications: A Potential Material for Healthcare Applications.". Pharmaceutics
(2019): http://europepmc.org/abstract/med/30987304.
10.3390/pharmaceutics11040165
- Maelíosa T. C. Mc Crudden; Eneko Larrañeta; Annie Clark; Courtney Jarrahian; Annie Rein-Weston; Benjamin Creelman; Yolanda
Moyo; et al. "Design, Formulation, and Evaluation of Novel Dissolving Microarray Patches Containing Rilpivirine for Intravaginal
Delivery". Advanced Healthcare Materials 8 9 (2019): 1801510-1801510. https://doi.org/10.1002%2Fadhm.201801510.
10.1002/adhm.201801510
- Universidade Estadual de Campinas (UNICAMP); Queen's University Belfast; Biológicas e Agrícolas; Universidade de São Paulo
(USP); Universidade Estadual Paulista (UNESP); University of Calabar; University at Campinas; et al. "Semisynthetic Derivative
of Artemisia annua-Loaded Transdermal Bioadhesive for the Treatment of Uncomplicated Malaria Caused by Plasmodium falciparum
in Children". Journal of Pharmaceutical Sciences 108 3 (2019): 1177-1188. http://hdl.handle.net/11449/189931.
http://dx.doi.org/10.1016/j.xphs.2018.10.007
- Cole, G.; Ali, A.A.; McErlean, E.; Mulholland, E.J.; Short, A.; McCrudden, C.M.; McCaffrey, J.; et al. "DNA vaccination via
RALA nanoparticles in a microneedle delivery system induces a potent immune response against the endogenous prostate cancer
stem cell antigen". Acta Biomaterialia 96 (2019): 480-490. http://www.scopus.com/inward/record.url?eid=2-s2.0-85069494362&partnerID=MN8TOARS.
10.1016/j.actbio.2019.07.003
- Ramöller, I.K.; Tekko, I.A.; McCarthy, H.O.; Donnelly, R.F.. "Rapidly dissolving bilayer microneedle arrays – A minimally
invasive transdermal drug delivery system for vitamin B12". International Journal of Pharmaceutics 566 (2019): 299-306.
http://www.scopus.com/inward/record.url?eid=2-s2.0-85066486176&partnerID=MN8TOARS.
10.1016/j.ijpharm.2019.05.066
- Rajoli, R.K.R.; Flexner, C.; Chiong, J.; Owen, A.; Donnelly, R.F.; Larrañeta, E.; Siccardi, M.. "Modelling the intradermal
delivery of microneedle array patches for long-acting antiretrovirals using PBPK". European Journal of Pharmaceutics and
Biopharmaceutics 144 (2019): 101-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072264262&partnerID=MN8TOARS.
10.1016/j.ejpb.2019.09.011
- Lamprou, D.A.; Singh, T.R.R.; Larrañeta, E.; Donnelly, R.F.. "How innovative drug delivery devices can help realize clinical
utility of new effective therapies". Expert Opinion on Drug Delivery 16 12 (2019): 1277-1281. http://www.scopus.com/inward/record.url?eid=2-s2.0-85075049677&partnerID=MN8TOARS.
10.1080/17425247.2019.1689956
- Permana, A.D.; Tekko, I.A.; McCrudden, M.T.C.; Anjani, Q.K.; Ramadon, D.; McCarthy, H.O.; Donnelly, R.F.. "Solid lipid nanoparticle-based
dissolving microneedles: A promising intradermal lymph targeting drug delivery system with potential for enhanced treatment
of lymphatic filariasis". Journal of Controlled Release 316 (2019): 34-52. http://www.scopus.com/inward/record.url?eid=2-s2.0-85074481097&partnerID=MN8TOARS.
10.1016/j.jconrel.2019.10.004
- Donnelly, R.F.; Larraneta, E.. "Slowly dissolving intradermal microneedles". Nature Biomedical Engineering 3 3 (2019):
169-170. http://www.scopus.com/inward/record.url?eid=2-s2.0-85074343145&partnerID=MN8TOARS.
10.1038/s41551-019-0369-4
- Permana, A.D.; McCrudden, M.T.C.; Donnelly, R.F.. "Enhanced intradermal delivery of nanosuspensions of antifilariasis drugs
using dissolving microneedles: A proof of concept study". Pharmaceutics 11 7 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85071376330&partnerID=MN8TOARS.
10.3390/pharmaceutics11070346
- Courtenay, A.J.; Rodgers, A.M.; McCrudden, M.T.C.; McCarthy, H.O.; Donnelly, R.F.. "Novel Hydrogel-Forming Microneedle Array
for Intradermal Vaccination in Mice Using Ovalbumin as a Model Protein Antigen". Molecular Pharmaceutics 16 1 (2019):
118-127. http://www.scopus.com/inward/record.url?eid=2-s2.0-85058153145&partnerID=MN8TOARS.
10.1021/acs.molpharmaceut.8b00895
- Permana, A.D.; Tekko, I.A.; McCarthy, H.O.; Donnelly, R.F.. "New HPLC–MS method for rapid and simultaneous quantification
of doxycycline, diethylcarbamazine and albendazole metabolites in rat plasma and organs after concomitant oral administration".
Journal of Pharmaceutical and Biomedical Analysis 170 (2019): 243-253. http://www.scopus.com/inward/record.url?eid=2-s2.0-85063586319&partnerID=MN8TOARS.
10.1016/j.jpba.2019.03.047
- Rodgers, A.M.; Cordeiro, A.S.; Donnelly, R.F.. "Technology update: Dissolvable microneedle patches for vaccine delivery".
Medical Devices: Evidence and Research 12 (2019): 379-398. http://www.scopus.com/inward/record.url?eid=2-s2.0-85073467359&partnerID=MN8TOARS.
10.2147/MDER.S198220
- Abdelghany, S.; Tekko, I.A.; Vora, L.; Larrañeta, E.; Permana, A.D.; Donnelly, R.F.. "Nanosuspension-based dissolving microneedle
arrays for intradermal delivery of curcumin". Pharmaceutics 11 7 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85071011605&partnerID=MN8TOARS.
10.3390/pharmaceutics11070308
- Gamazo, C.; Pastor, Y.; Larrañeta, E.; Berzosa, M.; Irache, J.M.; Donnelly, R.F.. "Understanding the basis of transcutaneous
vaccine delivery". Therapeutic Delivery 10 1 (2019): 63-80. http://www.scopus.com/inward/record.url?eid=2-s2.0-85058115130&partnerID=MN8TOARS.
10.4155/tde-2018-0054
- Pastor, Y.; Larrañeta, E.; Erhard, Á.; Quincooces, G.; Peñuelas, I.; Irache, J.M.; Donnelly, R.; Gamazo, C.. "Dissolving microneedles
for intradermal vaccination against shigellosis". Vaccines 7 4 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85074540222&partnerID=MN8TOARS.
10.3390/vaccines7040159
- Domínguez-Robles, J.; Stewart, S.A.; Rendl, A.; González, Z.; Donnelly, R.F.; Larrañeta, E.. "Lignin and cellulose blends
as pharmaceutical excipient for tablet manufacturing via direct compression". Biomolecules 9 9 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85071735141&partnerID=MN8TOARS.
10.3390/biom9090423
- Larrañeta, E.; Domínguez-Robles, J.; Coogan, M.; Heaney, E.; Stewart, S.A.; Thakur, R.R.S.; Donnelly, R.F.. "Poly(methyl vinyl
ether-co-maleic acid) Hydrogels Containing Cyclodextrins and Tween 85 for Potential Application as Hydrophobic Drug Delivery
Systems". Macromolecular Research 27 4 (2019): 396-403. http://www.scopus.com/inward/record.url?eid=2-s2.0-85059549839&partnerID=MN8TOARS.
10.1007/s13233-019-7074-8
- Khan, S.; Minhas, M.U.; Tekko, I.A.; Donnelly, R.F.; Thakur, R.R.S.. "Evaluation of microneedles-assisted in situ depot forming
poloxamer gels for sustained transdermal drug delivery". Drug Delivery and Translational Research 9 4 (2019): 764-782.
http://www.scopus.com/inward/record.url?eid=2-s2.0-85068617871&partnerID=MN8TOARS.
10.1007/s13346-019-00617-2
- Mc Crudden MTC; Larrañeta E; Clark A; Jarrahian C; Rein-Weston A; Lachau-Durand S; Niemeijer N; et al. "Design, formulation
and evaluation of novel dissolving microarray patches containing a long-acting rilpivirine nanosuspension.". Journal of
controlled release : official journal of the Controlled Release Society (2018): http://europepmc.org/abstract/med/30395897.
10.1016/j.jconrel.2018.11.002
- Rodgers AM; McCrudden MTC; Vincente-Perez EM; Dubois AV; Ingram RJ; Larrañeta E; Kissenpfennig A; Donnelly RF. "Design and
characterisation of a dissolving microneedle patch for intradermal vaccination with heat-inactivated bacteria: A proof of
concept study.". International journal of pharmaceutics (2018): http://europepmc.org/abstract/med/30048778.
10.1016/j.ijpharm.2018.07.049
- Donnelly, Ryan F. "DNA vaccination for cervical cancer: Strategic optimisation of RALA mediated gene delivery from a biodegradable
microneedle system". European Journal of Pharmaceutics and Biopharmaceutics (2018): http://dx.doi.org/10.1016/j.ejpb.2018.02.029.
10.1016/j.ejpb.2018.02.029
- Vora LK; Vavia PR; Larrañeta E; Bell SEJ; Donnelly RF. "Novel nanosuspension-based dissolving microneedle arrays for transdermal
delivery of a hydrophobic drug.". Journal of interdisciplinary nanomedicine (2018): http://europepmc.org/abstract/med/30069310.
10.1002/jin2.41
- Rodgers, A.M.; Courtenay, A.J.; Donnelly, R.F.. "Dissolving microneedles for intradermal vaccination: manufacture, formulation,
and stakeholder considerations". Expert Opinion on Drug Delivery 15 11 (2018): 1039-1043. http://www.scopus.com/inward/record.url?eid=2-s2.0-85053557776&partnerID=MN8TOARS.
10.1080/17425247.2018.1522301
- Rzhevskiy, A.S.; Singh, T.R.R.; Donnelly, R.F.; Anissimov, Y.G.. "Microneedles as the technique of drug delivery enhancement
in diverse organs and tissues". Journal of Controlled Release 270 (2018): 184-202. http://www.scopus.com/inward/record.url?eid=2-s2.0-85038006691&partnerID=MN8TOARS.
10.1016/j.jconrel.2017.11.048
- Donnelly, R.F.; Larrañeta, E.. "Microarray patches: potentially useful delivery systems for long-acting nanosuspensions".
Drug Discovery Today 23 5 (2018): 1026-1033. http://www.scopus.com/inward/record.url?eid=2-s2.0-85032295329&partnerID=MN8TOARS.
10.1016/j.drudis.2017.10.013
- Hutton, A.R.J.; Quinn, H.L.; McCague, P.J.; Jarrahian, C.; Rein-Weston, A.; Coffey, P.S.; Gerth-Guyette, E.; et al. "Transdermal
delivery of vitamin K using dissolving microneedles for the prevention of vitamin K deficiency bleeding". International
Journal of Pharmaceutics 541 1-2 (2018): 56-63. http://www.scopus.com/inward/record.url?eid=2-s2.0-85042369314&partnerID=MN8TOARS.
10.1016/j.ijpharm.2018.02.031
- Rodgers, A.M.; Cordeiro, A.S.; Kissenpfennig, A.; Donnelly, R.F.. "Microneedle arrays for vaccine delivery: the possibilities,
challenges and use of nanoparticles as a combinatorial approach for enhanced vaccine immunogenicity". Expert Opinion on
Drug Delivery 15 9 (2018): 851-867. http://www.scopus.com/inward/record.url?eid=2-s2.0-85053515989&partnerID=MN8TOARS.
10.1080/17425247.2018.1505860
- Courtenay, A.J.; McCrudden, M.T.C.; McAvoy, K.J.; McCarthy, H.O.; Donnelly, R.F.. "Microneedle-Mediated Transdermal Delivery
of Bevacizumab". Molecular Pharmaceutics 15 8 (2018): 3545-3556. http://www.scopus.com/inward/record.url?eid=2-s2.0-85049919515&partnerID=MN8TOARS.
10.1021/acs.molpharmaceut.8b00544
- Stewart, S.A.; Domínguez-Robles, J.; Donnelly, R.F.; Larrañeta, E.. "Implantable polymeric drug delivery devices: Classification,
manufacture, materials, and clinical applications". Polymers 10 12 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85058489443&partnerID=MN8TOARS.
10.3390/polym10121379
- Larrañeta, E.; Stewart, S.; Ervine, M.; Al-Kasasbeh, R.; Donnelly, R.F.. "Hydrogels for hydrophobic drug delivery. Classification,
synthesis and applications". Journal of Functional Biomaterials 9 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85049460294&partnerID=MN8TOARS.
10.3390/jfb9010013
- Hamdan, I.M.N.; Tekko, I.A.; Matchett, K.B.; Arnaut, L.G.; Silva, C.S.; McCarthy, H.O.; Donnelly, R.F.. "Intradermal Delivery
of a Near-Infrared Photosensitizer Using Dissolving Microneedle Arrays". Journal of Pharmaceutical Sciences 107 9 (2018):
2439-2450. http://www.scopus.com/inward/record.url?eid=2-s2.0-85049352962&partnerID=MN8TOARS.
10.1016/j.xphs.2018.05.017
- Pamornpathomkul, B.; Ngawhirunpat, T.; Tekko, I.A.; Vora, L.; McCarthy, H.O.; Donnelly, R.F.. "Dissolving polymeric microneedle
arrays for enhanced site-specific acyclovir delivery". European Journal of Pharmaceutical Sciences 121 (2018): 200-209.
http://www.scopus.com/inward/record.url?eid=2-s2.0-85048509812&partnerID=MN8TOARS.
10.1016/j.ejps.2018.05.009
- Migdadi, E.M.; Courtenay, A.J.; Tekko, I.A.; McCrudden, M.T.C.; Kearney, M.-C.; McAlister, E.; McCarthy, H.O.; Donnelly, R.F..
"Hydrogel-forming microneedles enhance transdermal delivery of metformin hydrochloride". Journal of Controlled Release
285 (2018): 142-151. http://www.scopus.com/inward/record.url?eid=2-s2.0-85049758140&partnerID=MN8TOARS.
10.1016/j.jconrel.2018.07.009
- Larrañeta, E.; Henry, M.; Irwin, N.J.; Trotter, J.; Perminova, A.A.; Donnelly, R.F.. "Synthesis and characterization of hyaluronic
acid hydrogels crosslinked using a solvent-free process for potential biomedical applications". Carbohydrate Polymers
181 (2018): 1194-1205. http://www.scopus.com/inward/record.url?eid=2-s2.0-85037700769&partnerID=MN8TOARS.
10.1016/j.carbpol.2017.12.015
- Quinn, H.L.; Hughes, C.M.; Donnelly, R.F.. "In vivo and qualitative studies investigating the translational potential of microneedles
for use in the older population". Drug Delivery and Translational Research 8 2 (2018): 307-316. http://www.scopus.com/inward/record.url?eid=2-s2.0-85042704069&partnerID=MN8TOARS.
10.1007/s13346-017-0393-4
- Donnelly, R.F.. "Preface". Recent Patents on Drug Delivery and Formulation 12 1 (2018): 2-2. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048994138&partnerID=MN8TOARS.
10.2174/187221131201180529125053
- Larrañeta, E.; Barturen, L.; Ervine, M.; Donnelly, R.F.. "Hydrogels based on poly(methyl vinyl ether-co-maleic acid) and Tween
85 for sustained delivery of hydrophobic drugs". International Journal of Pharmaceutics 538 1-2 (2018): 147-158. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041138028&partnerID=MN8TOARS.
10.1016/j.ijpharm.2018.01.025
- Larrañeta, E.; Imízcoz, M.; Toh, J.X.; Irwin, N.J.; Ripolin, A.; Perminova, A.; Domínguez-Robles, J.; Rodríguez, A.; Donnelly,
R.F.. "Synthesis and Characterization of Lignin Hydrogels for Potential Applications as Drug Eluting Antimicrobial Coatings
for Medical Materials". ACS Sustainable Chemistry and Engineering 6 7 (2018): 9037-9046. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048053069&partnerID=MN8TOARS.
10.1021/acssuschemeng.8b01371
- Thakur Singh, R.R.; Tekko, I.; McAvoy, K.; McMillan, H.; Jones, D.; Donnelly, R.F.. "Minimally invasive microneedles for ocular
drug delivery". Expert Opinion on Drug Delivery 14 4 (2017): 525-537. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014807467&partnerID=MN8TOARS.
10.1080/17425247.2016.1218460
- González-Vázquez, P.; Larrañeta, E.; McCrudden, M.T.C.; Jarrahian, C.; Rein-Weston, A.; Quintanar-Solares, M.; Zehrung, D.;
et al. "Transdermal delivery of gentamicin using dissolving microneedle arrays for potential treatment of neonatal sepsis".
Journal of Controlled Release 265 (2017): 30-40. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026836968&partnerID=MN8TOARS.
10.1016/j.jconrel.2017.07.032
- Ali, A.A.; McCrudden, C.M.; McCaffrey, J.; McBride, J.W.; Cole, G.; Dunne, N.J.; Robson, T.; et al. "DNA vaccination for cervical
cancer; a novel technology platform of RALA mediated gene delivery via polymeric microneedles". Nanomedicine: Nanotechnology,
Biology, and Medicine 13 3 (2017): 921-932. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013657113&partnerID=MN8TOARS.
10.1016/j.nano.2016.11.019
- Donnelly, R.F.. "How can microneedles overcome challenges facing transdermal drug delivery?". Therapeutic Delivery
8 9 (2017): 725-728. http://www.scopus.com/inward/record.url?eid=2-s2.0-85027831191&partnerID=MN8TOARS.
10.4155/tde-2017-0028
- Cole, G.; McCaffrey, J.; Ali, A.A.; McBride, J.W.; McCrudden, C.M.; Vincente-Perez, E.M.; Donnelly, R.F.; McCarthy, H.O..
"Dissolving microneedles for DNA vaccination: Improving functionality via polymer characterization and RALA complexation".
Human Vaccines and Immunotherapeutics 13 1 (2017): 50-62. http://www.scopus.com/inward/record.url?eid=2-s2.0-85006925429&partnerID=MN8TOARS.
10.1080/21645515.2016.1248008
- Ripolin, A.; Quinn, J.; Larrañeta, E.; Vicente-Perez, E.M.; Barry, J.; Donnelly, R.F.. "Successful application of large microneedle
patches by human volunteers". International Journal of Pharmaceutics 521 1-2 (2017): 92-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013157619&partnerID=MN8TOARS.
10.1016/j.ijpharm.2017.02.011
- Vicente-Perez, E.M.; Larrañeta, E.; McCrudden, M.T.C.; Kissenpfennig, A.; Hegarty, S.; McCarthy, H.O.; Donnelly, R.F.. "Repeat
application of microneedles does not alter skin appearance or barrier function and causes no measurable disturbance of serum
biomarkers of infection, inflammation or immunity in mice in vivo". European Journal of Pharmaceutics and Biopharmaceutics
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10.1016/j.ejpb.2017.04.029
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10.1111/j.1600-0781.2009.00410.x
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therapy using a novel bioadhesive patch-type system loaded with 5-aminolevulinic acid". Photodiagnosis and photodynamic
therapy 6 1 (2009): 28-40.
10.1016/j.pdpdt.2009.03.004
- Donnelly, R.F.; McCarron, P.A.; Woolfson, D.. "Drug delivery systems for photodynamic therapy". Recent Patents on Drug
Delivery and Formulation 3 1 (2009): 1-7. http://www.scopus.com/inward/record.url?eid=2-s2.0-60849112840&partnerID=MN8TOARS.
10.2174/187221109787158319
- Donnelly, R.F.; Morrow, D.I.J.; Singh, T.R.R.; Migalska, K.; McCarron, P.A.; O'Mahony, C.; Woolfson, A.D.. "Processing difficulties
and instability of carbohydrate microneedle arrays". Drug Development and Industrial Pharmacy 35 10 (2009): 1242-1254.
http://www.scopus.com/inward/record.url?eid=2-s2.0-70350689926&partnerID=MN8TOARS.
10.1080/03639040902882280
- Donnelly, R.F.; Singh, T.R.R.; Tunney, M.M.; Morrow, D.I.J.; McCarron, P.A.; O'Mahony, C.; Woolfson, A.D.. "Microneedle arrays
allow lower microbial penetration than hypodermic needles in vitro". Pharmaceutical Research 26 11 (2009): 2513-2522.
http://www.scopus.com/inward/record.url?eid=2-s2.0-70350215864&partnerID=MN8TOARS.
10.1007/s11095-009-9967-2
- Donnelly, Ryan F. "Practical considerations in the pharmaceutical analysis of methyl and hexyl ester derivatives of 5-aminolevulinic
acid". Open Analytical Chemistry Journal 3 (2009): 6-15.
10.2174/1874065000903010006
- Donnelly, R.F.; McCarron, P.A.; Tunney, M.M.. "Antifungal photodynamic therapy". Microbiological Research 163 1 (2008):
1-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-37049015780&partnerID=MN8TOARS.
10.1016/j.micres.2007.08.001
- Sibani, S.A.; McCarron, P.A.; Woolfson, A.D.; Donnelly, R.F.. "Photosensitiser delivery for photodynamic therapy. Part 2:
Systemic carrier platforms". Expert Opinion on Drug Delivery 5 11 (2008): 1241-1254. http://www.scopus.com/inward/record.url?eid=2-s2.0-57049143260&partnerID=MN8TOARS.
10.1517/17425240802444673
- Donnelly, R.F.. "Cover story". Journal of Controlled Release 129 3 (2008): 153-153. http://www.scopus.com/inward/record.url?eid=2-s2.0-47349110106&partnerID=MN8TOARS.
10.1016/j.jconrel.2008.06.013
- McCarron, P.A.; Donnelly, R.F.; Woolfson, A.D.. "Autoradiographic and scintillation analysis of 5-aminolevulinic acid permeation
through epithelialised tissue: Implications for topical photodynamic therapy of superficial gynaecological neoplasias". Pharmaceutical
Research 25 4 (2008): 812-826. http://www.scopus.com/inward/record.url?eid=2-s2.0-43349099482&partnerID=MN8TOARS.
10.1007/s11095-007-9352-y
- Donnelly, R.F.; Morrow, D.I.J.; McCarron, P.A.; Woolfson, A.D.; Morrissey, A.; Juzenas, P.; Juzeniene, A.; et al. "Microneedle-mediated
intradermal delivery of 5-aminolevulinic acid: Potential for enhanced topical photodynamic therapy". Journal of Controlled
Release 129 3 (2008): 154-162. http://www.scopus.com/inward/record.url?eid=2-s2.0-47349128121&partnerID=MN8TOARS.
10.1016/j.jconrel.2008.05.002
- Donnelly, Ryan F. "Aminolaevulinic acid diffusion characteristics in ‘in vitro’normal human skin and actinic keratosis: implications
for topical photodynamic therapy". Photodermatology, photoimmunology & photomedicine 24 4 (2008): 183-190.
10.1111/j.1600-0781.2008.00358.x
- McCarron, P.A.; Marouf, W.M.; Donnelly, R.F.; Scott, C.. "Enhanced surface attachment of protein-type targeting ligands to
poly(lactide-co-glycolide) nanoparticles using variable expression of polymeric acid functionality". Journal of Biomedical
Materials Research - Part A 87 4 (2008): 873-884. http://www.scopus.com/inward/record.url?eid=2-s2.0-56749163384&partnerID=MN8TOARS.
10.1002/jbm.a.31835
- Donnelly, R.F.; McCarron, P.A.; Morrow, D.I.J.; Sibani, S.A.; Woolfson, A.D.. "Photosensitiser delivery for photodynamic therapy.
Part 1: Topical carrier platforms". Expert Opinion on Drug Delivery 5 7 (2008): 757-766. http://www.scopus.com/inward/record.url?eid=2-s2.0-48349148670&partnerID=MN8TOARS.
10.1517/17425247.5.7.757
- Scott, C.J.; Marouf, W.M.; Quinn, D.J.; Buick, R.J.; Orr, S.J.; Donnelly, R.F.; McCarron, P.A.. "Immunocolloidal targeting
of the endocytotic siglec-7 receptor using peripheral attachment of siglec-7 antibodies to poly(lactide-co-glycolide) nanoparticles".
Pharmaceutical Research 25 1 (2008): 135-146. http://www.scopus.com/inward/record.url?eid=2-s2.0-38049178647&partnerID=MN8TOARS.
10.1007/s11095-007-9400-7
- Donnelly, R.; McNally, M.; Barry, J.. "Is extemporaneous dispensing really in the best interest of patients?". Pharmaceutical
Journal 280 7491 (2008): 251-253. http://www.scopus.com/inward/record.url?eid=2-s2.0-40949094491&partnerID=MN8TOARS.
- McCarron, P.A.; Donnelly, R.F.; Al-Kassas, R.. "Comparison of a novel spray congealing procedure with emulsion-based methods
for the micro-encapsulation of water-soluble drugs in low melting point triglycerides". Journal of Microencapsulation
25 6 (2008): 365-378. http://www.scopus.com/inward/record.url?eid=2-s2.0-49049095092&partnerID=MN8TOARS.
10.1080/02652040802000656
- Loughlin, R.G.; Tunney, M.M.; Donnelly, R.F.; Murphy, D.J.; Jenkins, M.; McCarron, P.A.. "Modulation of gel formation and
drug-release characteristics of lidocaine-loaded poly(vinyl alcohol)-tetraborate hydrogel systems using scavenger polyol sugars".
European Journal of Pharmaceutics and Biopharmaceutics 69 3 (2008): 1135-1146. http://www.scopus.com/inward/record.url?eid=2-s2.0-48149112133&partnerID=MN8TOARS.
10.1016/j.ejpb.2008.01.033
- Donnelly, R.F.; McCarron, P.A.; Tunney, M.M.; David Woolfson, A.. "Potential of photodynamic therapy in treatment of fungal
infections of the mouth. Design and characterisation of a mucoadhesive patch containing toluidine blue O". Journal of Photochemistry
and Photobiology B: Biology 86 1 (2007): 59-69. http://www.scopus.com/inward/record.url?eid=2-s2.0-33751552199&partnerID=MN8TOARS.
10.1016/j.jphotobiol.2006.07.011
- Donnelly, R.F.; McCarron, P.A.; Cassidy, C.M.; Elborn, J.S.; Tunney, M.M.. "Delivery of photosensitisers and light through
mucus: Investigations into the potential use of photodynamic therapy for treatment of Pseudomonas aeruginosa cystic fibrosis
pulmonary infection". Journal of Controlled Release 117 2 (2007): 217-226. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846545579&partnerID=MN8TOARS.
10.1016/j.jconrel.2006.11.010
- Morrow, D.I.J.; Garland, M.J.; McCarron, P.A.; Woolfson, A.D.; Donnelly, R.F.. "Innovative drug delivery strategies for topical
photodynamic therapy using porphyrin precursors". Journal of Environmental Pathology, Toxicology and Oncology 26 2
(2007): 105-116. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548078710&partnerID=MN8TOARS.
10.1615/JEnvironPatholToxicolOncol.v26.i2.50
- McCarron, P.A.; Andrews, G.P.; Morrow, D.I.J.; Woolfson, A.D.; Donnelly, R.F.. "Formulation and characterization of poly(ethylene
glycol)-based, 5-aminolevulinic acid-loaded solid-dosage forms intended for photodynamic and photodiagnostic methodologies
in the colorectal region". Journal of Environmental Pathology, Toxicology and Oncology 26 2 (2007): 135-142. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548060949&partnerID=MN8TOARS.
10.1615/JEnvironPatholToxicolOncol.v26.i2.80
- McCarron, P.A.; Donnelly, R.F.; Marouf, W.; Calvert, D.E.. "Anti-adherent and antifungal activities of surfactant-coated poly(ethylcyanoacrylate)
nanoparticles". International Journal of Pharmaceutics 340 1-2 (2007): 182-190. http://www.scopus.com/inward/record.url?eid=2-s2.0-34447263811&partnerID=MN8TOARS.
10.1016/j.ijpharm.2007.03.029
- Donnelly, Ryan F. "Derivatives of 5-aminolevulinic acid for photodynamic therapy". Perspectives in medicinal chemistry
1 (2007): 49-49.
- Donnelly, Ryan F. "Innovative strategies for enhancing topical and transdermal drug delivery". The open drug delivery journal
1 (2007): 36-59.
10.2174/1874126600701010036
- Donnelly, R.F.; Morrissey, A.; McCarron, P.A.; Woolfson, D.A.. "Microstructured devices for transdermal drug delivery and
minimally-invasive patient monitoring.". Recent patents on drug delivery & formulation 1 3 (2007): 195-200. http://www.scopus.com/inward/record.url?eid=2-s2.0-63149129759&partnerID=MN8TOARS.
10.2174/187221107782331656
- Donnelly, R.F.; Morrow, D.I.J.; McCarron, P.A.; Garland, M.J.; Woolfson, A.D.. "Influence of solution viscosity and injection
protocol on distribution patterns of jet injectors: Application to photodynamic tumour targeting". Journal of Photochemistry
and Photobiology B: Biology 89 2-3 (2007): 98-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-36448956821&partnerID=MN8TOARS.
10.1016/j.jphotobiol.2007.09.009
- Barry, J.G.; Colville, J.A.; Donnelly, R.F.. "Attitudes of pharmacy students and community pharmacists to numeracy". Pharmacy
Education 7 2 (2007): 123-131. http://www.scopus.com/inward/record.url?eid=2-s2.0-34347268136&partnerID=MN8TOARS.
10.1080/15602210701264850
- Zawislak, A.A.; McCarron, P.A.; McCluggage, W.G.; Donnelly, R.F.; Price, J.H.; McClelland, H.R.; Woolfson, A.D.. "Novel bioadhesive
patch-type system for photodynamic vulvodynia therapy after delivery of 5-aminolevulinic acid: Preliminary evaluation". Journal
of Reproductive Medicine for the Obstetrician and Gynecologist 52 7 (2007): 645-653. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547115008&partnerID=MN8TOARS.
- Donnelly, R.F.. "Brains and brawn united". Pharmaceutical Technology Europe 19 6 (2007): 66-66. http://www.scopus.com/inward/record.url?eid=2-s2.0-34250809611&partnerID=MN8TOARS.
- Donnelly, R.F.; Fletcher, N.C.; McCague, P.J.; Donnelly, J.; McCarron, P.A.; Tunney, M.M.. "Design, synthesis and Photodynamic
antimicrobial activity of ruthenium trischelate diimine complexes". Letters in Drug Design and Discovery 4 3 (2007):
175-179. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947545074&partnerID=MN8TOARS.
10.2174/157018007780077390
- McCarron, P.A.; Donnelly, R.F.; Marouf, W.. "Celecoxib-loaded poly(D,L-lactide-co-glycolide) nanoparticles prepared using
a novel and controllable combination of diffusion and emulsification steps as part of the salting-out procedure". Journal
of Microencapsulation 23 5 (2006): 480-498. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749008500&partnerID=MN8TOARS.
10.1080/02652040600682390
- Donnelly, R.F.; Ma, L.-W.; Juzenas, P.; Iani, V.; McCarron, P.A.; Woolfson, A.D.; Moan, J.. "Topical bioadhesive patch systems
enhance selectivity of protoporphyrin IX accumulation". Photochemistry and Photobiology 82 3 (2006): 670-675. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745859015&partnerID=MN8TOARS.
10.1562/2005-08-08-RA-641
- Donnelly, R.F.; Morrow, D.I.J.; McCarron, P.A.; Juzenas, P.; Woolfson, A.D.. "Pharmaceutical analysis of 5-aminolevulinic
acid in solution and in tissues". Journal of Photochemistry and Photobiology B: Biology 82 1 (2006): 59-71. http://www.scopus.com/inward/record.url?eid=2-s2.0-29644438626&partnerID=MN8TOARS.
10.1016/j.jphotobiol.2005.08.007
- McCarron, P.A.; Donnelly, R.F.; Zawislak, A.; Woolfson, A.D.. "Design and evaluation of a water-soluble bioadhesive patch
formulation for cutaneous delivery of 5-aminolevulinic acid to superficial neoplastic lesions". European Journal of Pharmaceutical
Sciences 27 2-3 (2006): 268-279. http://www.scopus.com/inward/record.url?eid=2-s2.0-29244481149&partnerID=MN8TOARS.
10.1016/j.ejps.2005.10.009
- Donnelly, R.F.; Juzenas, P.; McCarron, P.A.; Ma, L.-W.; Woolfson, A.D.; Moan, J.. "Influence of formulation factors on methyl-ALA-induced
protoporphyrin IX accumulation in vivo". Photodiagnosis and Photodynamic Therapy 3 3 (2006): 190-201. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846426427&partnerID=MN8TOARS.
10.1016/j.pdpdt.2006.03.007
- Donnelly, R.F.; McCarron, P.A.; Zawislak, A.A.; David Woolfson, A.. "Design and physicochemical characterisation of a bioadhesive
patch for dose-controlled topical delivery of imiquimod". International Journal of Pharmaceutics 307 2 (2006): 318-325.
http://www.scopus.com/inward/record.url?eid=2-s2.0-29244452660&partnerID=MN8TOARS.
10.1016/j.ijpharm.2005.10.023
- Donnelly, R.F.; McCarron, P.A.; Ma, L.-W.; Juzenas, P.; Lani, V.; Woolfson, A.D.; Zawislak, A.A.; Moan, J.. "Facilitated delivery
of ALA to inaccessible regions via bioadhesive patch systems". Journal of Environmental Pathology, Toxicology and Oncology
25 1-2 (2006): 389-402. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644747532&partnerID=MN8TOARS.
- Gilmore, B.F.; McCarron, P.A.; Morrow, D.I.J.; Murphy, D.J.; Woolfson, A.D.; Donnelly, R.F.. "In vitro phototoxicity of 5-aminolevulinic
acid and its methyl ester and the influence of barrier properties on their release from a bioadhesive patch". European
Journal of Pharmaceutics and Biopharmaceutics 63 3 (2006): 295-309. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646853695&partnerID=MN8TOARS.
10.1016/j.ejpb.2006.03.002
- Donnelly, Ryan F. "Excipient-Excipient Interactions in Pharmaceutical Systems Intended for Topical Application". (2005):
- Donnelly, R.F.; McCarron, P.A.; Lightowler, J.M.; Woolfson, A.D.. "Bioadhesive patch-based delivery of 5-aminolevulinic acid
to the nail for photodynamic therapy of onychomycosis". Journal of Controlled Release 103 2 (2005): 381-392. http://www.scopus.com/inward/record.url?eid=2-s2.0-14844312114&partnerID=MN8TOARS.
10.1016/j.jconrel.2004.12.005
- Donnelly, R.F.; McCarron, P.A.; Woolfson, A.D.. "Drug delivery of aminolevulinic acid from topical formulations intended for
photodynamic therapy". Photochemistry and Photobiology 81 4 (2005): 750-767. http://www.scopus.com/inward/record.url?eid=2-s2.0-24644507024&partnerID=MN8TOARS.
10.1562/2004-08-23-IR-283R1.1
- McCarron, P.A.; Donnelly, R.F.; Woolfson, A.D.; Andrews, G.P.. "Analysis of pyrazine 2,5-dipropionic acid in 5-aminolevulinic
acid-loaded urological and topical delivery vehicles: Methodology and assay validation". Journal of Pharmaceutical and
Biomedical Analysis 36 5 (2005): 1099-1105. http://www.scopus.com/inward/record.url?eid=2-s2.0-11144269674&partnerID=MN8TOARS.
10.1016/j.jpba.2004.09.004
- McCarron, P.A.; Donnelly, R.F.; Andrews, G.P.; Woolfson, A.D.. "Stability of 5-aminolevulinic acid in novel non-aqueous gel
and patch-type systems intended for topical application". Journal of Pharmaceutical Sciences 94 8 (2005): 1756-1771.
http://www.scopus.com/inward/record.url?eid=2-s2.0-25444443373&partnerID=MN8TOARS.
10.1002/jps.20393
- McCarron, P.A.; Donnelly, R.F.; Zawislak, A.; Woolfson, A.D.; Price, J.H.; McClelland, R.. "Evaluation of a water-soluble
bioadhesive patch for photodynamic therapy of vulval lesions". International Journal of Pharmaceutics 293 1-2 (2005):
11-23. http://www.scopus.com/inward/record.url?eid=2-s2.0-15044350118&partnerID=MN8TOARS.
10.1016/j.ijpharm.2004.11.035
- Ahmadi, S.; McCarron, P.A.; Donnelly, R.F.; Woolfson, A.D.; McKeena, K.. "Evaluation of the penetration of 5-aminolevulinic
acid through basal cell carcinoma: A pilot study". Experimental Dermatology 13 7 (2004): 445-451. http://www.scopus.com/inward/record.url?eid=2-s2.0-4043110527&partnerID=MN8TOARS.
10.1111/j.0906-6705.2004.00181.x
- Zawislak, A.A.; McCarron, P.A.; McCluggage, W.G.; Price, J.H.; Donnelly, R.F.; McClelland, H.R.; Dobbs, S.P.; Woolfson, A.D..
"Successful photodynamic therapy of vulval Paget's disease using a novel patch-based delivery system containing 5-aminolevulinic
acid". BJOG: An International Journal of Obstetrics and Gynaecology 111 10 (2004): 1143-1145. http://www.scopus.com/inward/record.url?eid=2-s2.0-4844230007&partnerID=MN8TOARS.
10.1111/j.1471-0528.2004.00254.x
- Donnelly, Ryan F. "Phototoxicity of 5-aminolevulinic acid in the HeLa cell line as an indicative measure of photodynamic effect
after topical administration to gynecological lesions of intraepithelial form". Pharmaceutical research 21 10 (2004):
1871-1879.
10.1023/B:PHAM.0000045242.98628.0b
- McCarron, P.A.; Woolfson, A.D.; Donnelly, R.F.; Andrews, G.P.; Zawislak, A.; Price, J.H.. "Influence of plasticizer type and
storage conditions on properties of poly(methyl vinyl ether-co-maleic anhydride) bioadhesive films". Journal of Applied
Polymer Science 91 3 (2004): 1576-1589. http://www.scopus.com/inward/record.url?eid=2-s2.0-1642544609&partnerID=MN8TOARS.
10.1002/app.13228
- Donnelly, Ryan F. "Bioadhesive, non-drug-loaded nanoparticles as modulators of candidal adherence to buccal epithelial cells:
a potentially novel prophylaxis for candidosis". Biomaterials 25 12 (2004): 2399-2407.
10.1016/j.biomaterials.2003.09.022
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