Maria Emilia Carreira Saraiva Monteiro (5918-54A6-FAA0)

Curriculum Vitae

Maria Emilia Carreira Saraiva Monteiro

Maria Emilia Carreira Saraiva Monteiro is a Medical Doctor (Universidad de Navarra, Spain) and full professor of Pharmacology at Nova Medical School, Universidade Nova de Lisboa. Has a PhD in Biomedical Sciences (1994) by Universidade do Porto (Portugal) and a PhD in Physiology by Universidad de Navarra. She is senior investigator at CEDOC-iNOVA4Health, coordinates the thematic line ¿Cardio Metabolic disorders¿ and is member of the executive committee of INOVA4Health research unit (graded with Excellent by the Portuguese funding agency). Her main scientific interests are pharmacology of cardiovascular diseases related with oxygen disturbances; drug-related adverse effects and research infrastructures for clinical research . Supervised 11 PhD thesis already finished, published 88 scientific articles that generated 1423 Citations and has 3 on going research grants supported by competitive funds (1 ERASMUS+). Presently, coordinates PtCRIN ¿ Portuguese Clinical Research Infrastructure network, integrated in the national and European roadmap of research infrastructures; is member (evaluation of clinical trials) of the National Ethics Committee for Clinical Research (CEIC); is senior clinical and scientific lead of the academic clinical trial unit NOVACRU; is member of the Collaborative-CoLab Trials (a public-private association supported by european infrastructure funds to foster innovation); is member of the scientific council of the ANSM ¿Agence Nationale de Sécurité du Medicament et des Produits de Santé¿ (France) and full member and Treasure of the Portuguese Academy of Medicine representing the academy in FEAM. Was vice-dean for education of Nova Medical School from 2010-2017 and Delegate of Portugal in the FP 7 and Horizon 2020- topic, SC1 "Health, demographic change and wellbeing". Has been involved in the evaluation of research infrastructures in the Czech Republic; member of the ¿Comité Científico Asesor Externo de SCReN¿, (Spanish Clinical Research network); co-director of the Portugal Clinical Scholars Research Training (PTCSRT) from Harvard Medical School (2012-2022); President of the International Society for Arterial Chemoreception (ISAC) and of the Portuguese Society of Pharmacology. She is the chair of curricular units in under graduate (Pharmacology in medicine) and graduate programes (Core methodologies in biomedical and clinical research - PhD program in Health Sciences, NOVA Medical School) and involved in several graduate programes in the area of clinical research and pharmaceutical medicine.

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Identificação

Identificação pessoal

Nome completo: Maria Emilia Carreira Saraiva Monteiro

Nomes de citação

Monteiro, EC

Identificadores de autor

Ciência ID: 5918-54A6-FAA0
ORCID iD: 0000-0002-0570-0765

Moradas

Campo Mártires da Pátria, 130, 1150-090, Lisbon, Lisbon, Portugal (Profissional)

Websites

https://www.nms.unl.pt/pt-pt/investigacao/grupos-de-investigacao (Profissional)

Domínios de atuação

Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia
Ciências Médicas e da Saúde - Ciências da Saúde
Ciências Médicas e da Saúde - Medicina Clínica
Ciências Médicas e da Saúde - Medicina Clínica

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão	Peer-review
Português (Idioma materno)
Inglês	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)
Espanhol; Castelhano	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)

Formação

	Grau	Classificação
2008 Concluído	Habilitation (Outros) Universidade Nova de Lisboa, Portugal
1994 Concluído	PhD in Medicine (Doutoramento) Especialização em Pharmacology Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal "Efeitos Respiratórios e Cardiovasculares da Adenosina in Vivo" (TESE/DISSERTAÇÃO)
1984 Concluído	PhD in Medicine (Doutoramento) Especialização em Physiology Universidad de Navarra Facultad de Medicina, Espanha
1982 Concluído	Medicine (Licenciatura) Universidad de Navarra Facultad de Medicina, Espanha

Percurso profissional

Docência no Ensino Superior

	Categoria Profissional Instituição de acolhimento	Empregador
2012 - Atual	Professor Catedrático (Docente Universitário)	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Cargos e Funções

	Categoria Profissional Instituição de acolhimento	Empregador
2021 - Atual	Council Member, Portuguese Academy of Medicine representative	Federation of European Academies of Medicine, FEAM, Bélgica
	Federation of European Academies of Medicine, FEAM, Bélgica
2021 - Atual	Coordinator of the PhD grant panel, Clinical Medicine and Health Sciences	Fundação para a Ciência e a Tecnologia, Portugal
	Fundação para a Ciência e a Tecnologia, Portugal
2020 - Atual	Coordinator of the National Roadmap Infrastructure	PtCRIN, Portuguese Clinical Research Infrastructure Network, Portugal
	PtCRIN, Portuguese Clinical Research Infrastructure Network, Portugal (...)
2019 - Atual	Chair of the Curricular Unit Core Methodologies in Biomedical and Clinical Research, PhD Program in Health Sciences	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019 - Atual	Chair of the Curricular Unit Pathophysiology and Therapeutic Targets, Integrated Master in Medicine	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2018 - Atual	Coordinator of the Thematic Line "Cardio Metabolic Disorders" of the Portuguese Research Unit iNOVA4health	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
	iNOVA4Health, Portugal
2018 - Atual	iNOVA4Health Management Board	Universidade Nova de Lisboa, Portugal
	iNOVA4Health, Portugal
2014 - Atual	Member of the Network Committee	European Clinical Research Infrastructure Network, França
	European Clinical Research Infrastructure Network, França
2013 - Atual	Senior Clinical and Scientific lead of the academic clinical trial unit NOVACRU	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2013 - Atual	Member of the Scientific Council	Agence nationale de sécurité du médicament et des produits de santé, França
	Agence nationale de sécurité du médicament et des produits de santé, França
2012 - Atual	Coordinator of the Portuguese Cinical Research Infraestructures Network (PtCRIN), the national partner of the ECRIN/ERIC	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2009 - Atual	Member	CEIC, Comissão de Ética para a Investigação Clínica, Portugal
	CEIC, Comissão de Ética para a Investigação Clínica, Portugal
2008 - Atual	Principal Investigator of the research group of Translational Pharmacology	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal (...)
2015 - 2022	Co-Director, Portugal Clinical Scholars Research Training (PTCSRT)	Harvard Medical School, Estados Unidos
	Harvard Medical School, Estados Unidos
2017 - 2020	Chair of the Curricular Unit Medical Devices, Integrated Master in Medicine	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2003 - 2018	Chair of the Curricular Units Pharmacology and/or General Pharmacology, Integrated Master of Medicine	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2010 - 2017	Subdirector de Unidade Orgânica	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Outros

	Categoria Profissional Instituição de acolhimento	Empregador
2020 - Atual	CEDOC (Chronic Diseases Center)_Member of the executive board	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
	Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal

Projetos

Bolsa

	Designação	Financiadores
2021/11/01 - 2024/10/31	Conscious II, Curriculum development of Human Clinical Trials 2021-1-CZ01-KA220-HED-000023177 Investigador Universidade Nova de Lisboa, Portugal	European Commission Em curso
2020 - 2022	Relevance of the Ratio Kynurenine/Tryptophan to Characterize Hypertension Associated to Obstructive Sleep Apnea (KYNTOSA) PTDC/MED-TOX30418/2017 Investigador responsável Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal	Em curso
2019 - 2021	CONSCIOUS, Curriculum Development of Human Clinical Trials for the Next Generation Biomedical Students 2018-1-HU01-KA203-047811 Investigador Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal	European Commission Concluído

Projeto

	Designação	Financiadores
2020 - Atual	Muscle up with intermittent hypoxia: a matter of intensity, gender and metabolism iNOVA4Health- IUDB/004462/2020/TL2/P2 Investigador Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal iNOVA4Health, Portugal	iNOVA4Health Fundação para a Ciência e a Tecnologia Em curso
2018 - Atual	AhR-CYP1A: linking environmental exposure and sleep apnea to improve arterial hypertension management PTDC/MED-TOX/30418/2017 Investigador responsável Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2017 - Atual	Efficacy of olive oil and phenolic compounds in reversing hypertension induced by chronic intermittent hypoxia FCT20160102021 iNOVA4Health – MULTI/04462 iNOVA4Health MULTI/04462 Investigador iNOVA4Health, Portugal	Fundação para a Ciência e a Tecnologia iNOVA4Health Em curso
2014 - 2024	Portuguese Clinical Research Infrastructures network (PtCRIN) 2013/713/EU Investigador responsável Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2019 - 2021	Variability of 1A1 sulfotransferase activity in humans: an approach to predict drug response - 2nd part: Analysis of inter-individual variability in hypertensive patients. EudraCT 2019-002266-12 and CEIC 20191098 Orientador Hospital da Luz Lisboa, Portugal	Em curso
2016 - 2019	Variability of sulfotransferase 1A1 activity in humans: an approach to improve predictive drug response? Part I: Analysis of intraindividual variation in healthy adults Protocol nº HLUZ_001_2016; EudraCT nº: 2016-001395-29 Investigador responsável Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal	Hospital da Luz Lisboa Concluído
2011 - 2014	Hepatic toxicity in HIVinfected individuals exposed to nevirapine PTDC/SAUORG/ 111663/2009 Investigador responsável	Fundação para a Ciência e a Tecnologia
2011 - 2014	Chronic Intermitent Eucapnic Hypoxia: systemic effects and evaluation of antihypertensive drugs efficacy PTDC/SAUTOX/112264/2009 Investigador responsável	Fundação para a Ciência e a Tecnologia Concluído

Produções

Publicações

Artigo em conferência	Gracio, Patricia C.; Goncalves-Dias, Clara; Lopes-Coelho, Filipa; Monteiro, Emilia C.; Serpa, Jacinta; da Silva, Claudia L.; Pereira, Sofia A.. "Changes in N-acetyltransferase 8 in kidney tubular cell: injury, recovery and mesenchymal stromal cell-based therapy". 2019. 10.1109/enbeng.2019.8692517 Diogo, Lucilia N.; Pereira, Sofia A.; Nunes, Ana R.; Afonso, Ricardo A.; Santos, Ana I.; Monteiro, Emilia C.. "Hypertension induced by chronic intermittent hypoxia: Effects of carvedilol in a rat model". 2015. 10.1183/13993003.congress-2015.oa294
Artigo em revista	Correia, Maria João; Pimpão, António B.; Fernandes, Dalila G. F.; Morello, Judit; Sequeira, Catarina O.; Calado, Joaquim; Antunes, Alexandra M. M.; et al. "Cysteine as a Multifaceted Player in Kidney, the Cysteine-Related Thiolome and Its Implications for Precision Medicine". Molecules 27 4 (2022): 1416. http://dx.doi.org/10.3390/molecules27041416. Publicado • 10.3390/molecules27041416 Coelho, N. R.; Pimpão, A. B.; Correia, M. J.; Rodrigues, T. C.; Monteiro, E. C.; Morello, J.; Pereira, S. A.. "Pharmacological blockage of the AHR-CYP1A1 axis: a call for in vivo evidence". Journal of Molecular Medicine 100 2 (2021): 215-243. http://dx.doi.org/10.1007/s00109-021-02163-2. Publicado • 10.1007/s00109-021-02163-2 Pinheiro Andrade, Maria; Matias, Daniela; Batuca, Joana; Gouveia, Nélia; Mota-Filipe, Hélder; Carreira Monteiro, Emília; Madeira, Catarina. "Portuguese Authorship in Published Clinical Trials: Differences in Industry and Investigator Initiated Trials". Acta Médica Portuguesa 34 11 (2021): 733. http://dx.doi.org/10.20344/amp.14554. Publicado • 10.20344/amp.14554 Correia, Maria João; Pimpão, António B.; Lopes-Coelho, Filipa; Sequeira, Catarina O.; Coelho, Nuno R.; Gonçalves-Dias, Clara; Barouki, Robert; et al. "Aryl Hydrocarbon Receptor and Cysteine Redox Dynamics Underlie (Mal)adaptive Mechanisms to Chronic Intermittent Hypoxia in Kidney Cortex". Antioxidants 10 9 (2021): 1484. http://dx.doi.org/10.3390/antiox10091484. Publicado • 10.3390/antiox10091484 Martins, Fátima O.; Sacramento, Joana F.; Olea, Elena; Melo, Bernardete F.; Prieto-Lloret, Jesus; Obeso, Ana; Rocher, Asuncion; et al. "Chronic Intermittent Hypoxia Induces Early-Stage Metabolic Dysfunction Independently of Adipose Tissue Deregulation". Antioxidants 10 8 (2021): 1233. http://dx.doi.org/10.3390/antiox10081233. Publicado • 10.3390/antiox10081233 Marto, Natalia; Morello, Judit; Antunes, Alexandra; Monteiro, Emília; Pereira, Sofia. "Phenotyping SULT in Man: a Simple Metric Using Paracetamol as Probe". The FASEB Journal 35 S1 (2021): http://dx.doi.org/10.1096/fasebj.2021.35.s1.03064. Publicado • 10.1096/fasebj.2021.35.s1.03064 Marto, Natália; Morello, Judit; Antunes, Alexandra M. M.; Azeredo, Sofia; Monteiro, Emília C.; Pereira, Sofia A.. "A simple method to measure sulfonation in man using paracetamol as probe drug". Scientific Reports 11 1 (2021): http://dx.doi.org/10.1038/s41598-021-88393-3. 10.1038/s41598-021-88393-3 Marinho, Aline T.; Batuca, Joana R.; Miranda, Joana P.; Caixas, Umbelina; Dias, Clara G.; Branco, Teresa; Soto, Karina; et al. "The 2-hydroxy-nevirapine metabolite as a candidate for boosting apolipoprotein A1 and for modulating anti-HDL antibodies". Pharmacological Research (2021): 105446. http://dx.doi.org/10.1016/j.phrs.2021.105446. 10.1016/j.phrs.2021.105446 Coelho, Nuno R.; Matos, Clara; Pimpão, António B.; Correia, M. João; Sequeira, Catarina O.; Morello, Judit; Pereira, Sofia A.; Monteiro, Emília C.. "AHR canonical pathway: in vivo findings to support novel antihypertensive strategies". Pharmacological Research (2021): 105407. http://dx.doi.org/10.1016/j.phrs.2020.105407. 10.1016/j.phrs.2020.105407 Brinkman DJ; Monteiro T; Monteiro EC; Richir MC; van Agtmael MA; Tichelaar J. "Switching from a traditional undergraduate programme in (clinical) pharmacology and therapeutics to a problem-based learning programme.". European journal of clinical pharmacology (2020): http://europepmc.org/abstract/med/33098019. 10.1007/s00228-020-03027-3 Helena Pite; Laura Aguiar; Judit Morello; Emilia Monteiro; Ana Catarina Alves; Mafalda Bourbon; Mário Morais-Almeida. " Metabolic Dysfunction and Asthma: Current Perspectives ". Journal of Asthma and Allergy (2020): https://doi.org/10.2147/JAA.S208823. 10.2147/JAA.S208823 Marto N; Monteiro EC. "Medicines for the Treatment Of COVID-19: Awaiting the Evidence.". Acta medica portuguesa (2020): http://europepmc.org/abstract/med/32425152. 10.20344/amp.13908 Coelho NR; Tomkiewicz C; Correia MJ; Gonçalves-Dias C; Barouki R; Pereira SA; Coumoul X; Monteiro EC. "First evidence of aryl hydrocarbon receptor as a druggable target in hypertension induced by chronic intermittent hypoxia.". Pharmacological research (2020): http://europepmc.org/abstract/med/32416216. 10.1016/j.phrs.2020.104869 Magnin, Annette; Iversen, Valentina Cabral; Calvo, Gonzalo; Cecetková, Beata; Dale, Ola; Demlová, Regina; Blaskó, György; et al. "European survey on national harmonization in clinical research". Learning Health Systems 5 2 (2020): http://dx.doi.org/10.1002/lrh2.10220. Publicado • 10.1002/lrh2.10220 Magnin, A.; Iversen, V. Cabral; Calvo, G.; Cecetková, B.; Dale, O.; Demlova, R.; Blasko, Gy.; et al. "European survey on national training activities in clinical research". Trials 20 1 (2019): http://dx.doi.org/10.1186/s13063-019-3702-z. 10.1186/s13063-019-3702-z Joana F. Sacramento; Elena Olea; Maria J. Ribeiro; Jesus Prieto-Lloret; Bernardete F. Melo; Constancio Gonzalez; Fatima O. Martins; Emilia C. Monteiro; Silvia V. Conde. "Contribution of adenosine and ATP to the carotid body chemosensory activity in ageing". The Journal of Physiology (2019): https://doi.org/10.1113/JP274179. 10.1113/JP274179 Monteiro, Maria. "Appropriate antibiotic prescribing among final-year medical students in Europe". International Journal of Antimicrobial Agents (2019): http://dx.doi.org/10.1016/j.ijantimicag.2019.05.008. 10.1016/j.ijantimicag.2019.05.008 Monteiro, Maria. "Transparency and accuracy in funding investigator-initiated clinical trials: a systematic search in clinical trials databases". BMJ Open (2019): http://dx.doi.org/10.1136/bmjopen-2018-023394. 10.1136/bmjopen-2018-023394 Gonçalves-Dias; Morello; Semedo; Correia; Coelho; Monteiro; Antunes; Pereira. "The mercapturomic profile of health and non-communicable diseases". High-Throughput 8 2 (2019): 10-10. https://doi.org/10.3390/ht8020010. 10.3390/ht8020010 Monteiro, Maria. "Mercapturate Pathway in the Tubulocentric Perspective of Diabetic Kidney Disease". Nephron (2019): http://dx.doi.org/10.1159/000494390. 10.1159/000494390 Aline T. Marinho; Joana P. Miranda; Umbelina Caixas; Catarina Charneira; Clara Gonçalves-Dias; M. Matilde Marques; Emília C. Monteiro; Alexandra M. M. Antunes; Sofia A. Pereira. "Singularities of nevirapine metabolism: from sex-dependent differences to idiosyncratic toxicity". Drug Metabolism Reviews 51 1 (2019): 76-90. https://doi.org/10.1080/03602532.2019.1577891. 10.1080/03602532.2019.1577891 Morello, Judit; Derks, Rico J. E.; Lopes, Susana S.; Steenvoorden, Evelyne; Monteiro, Emilia C.; Mayboroda, Oleg A.; Pereira, Sofia A.. "Zebrafish Larvae Are a Suitable Model to Investigate the Metabolic Phenotype of Drug-Induced Renal Tubular Injury". Frontiers in Pharmacology 9 (2018): http://dx.doi.org/10.3389/fphar.2018.01193. 10.3389/fphar.2018.01193 Brinkman DJ; Tichelaar J; Mokkink LB; Christiaens T; Likic R; Maciulaitis R; Costa J; et al. "Key learning outcomes for clinical pharmacology and therapeutics education in Europe: A modified Delphi study.". Clinical pharmacology and therapeutics (2017): http://europepmc.org/abstract/med/29205299. 10.1002/cpt.962 Gorgulho R; Jacinto R; Lopes SS; Pereira SA; Tranfield EM; Martins GG; Gualda EJ; et al. "Usefulness of zebrafish larvae to evaluate drug-induced functional and morphological renal tubular alterations.". Archives of toxicology (2017): http://europepmc.org/abstract/med/28932931. 10.1007/s00204-017-2063-1 Marto N; Morello J; Monteiro EC; Pereira SA. "Implications of sulfotransferase activity in interindividual variability in drug response: clinical perspective on current knowledge.". Drug metabolism reviews (2017): http://europepmc.org/abstract/med/28554218. 10.1080/03602532.2017.1335749 Grilo NM; João Correia M; Miranda JP; Cipriano M; Serpa J; Matilde Marques M; Monteiro EC; et al. "Unmasking efavirenz neurotoxicity: Time matters to the underlying mechanisms.". European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences (2017): http://europepmc.org/abstract/med/28487145. 10.1016/j.ejps.2017.05.010 Brinkman DJ; Tichelaar J; Schutte T; Benemei S; Böttiger Y; Chamontin B; Christiaens T; et al. "Essential competencies in prescribing: A first european cross-sectional study among 895 final-year medical students.". Clinical pharmacology and therapeutics (2017): http://europepmc.org/abstract/med/27648725. 10.1002/cpt.521 Conde SV; Monteiro EC; Sacramento JF. "Purines and Carotid Body: New Roles in Pathological Conditions.". Frontiers in pharmacology (2017): http://europepmc.org/abstract/med/29311923. 10.3389/fphar.2017.00913 Grilo NM; Correia MJ; Sequeira C; Harjivan SG; Caixas U; Diogo LN; Marques MM; et al. "Efavirenz biotransformation as an up-stream event of mood changes in HIV-infected patients.". Toxicology letters (2016): http://europepmc.org/abstract/med/27543169. 10.1016/j.toxlet.2016.08.009 Pedroso D; Nunes AR; Diogo LN; Oudot C; Monteiro EC; Brenner C; Vieira HLA. "Hippocampal neurogenesis response: What can we expect from two different models of hypertension?". Brain research (2016): http://europepmc.org/abstract/med/27235865. 10.1016/j.brainres.2016.05.044 Vera-Cruz P; Rito M; Diogo L; Zagalo C; Dos Santos JM; Monteiro ME. "Structure of the rat tracheal mucosa after chronic intermittent hypoxia or chronic hyperbaric oxygen therapy.". (2016): http://europepmc.org/abstract/med/26648111. 10.14670/HH-11-703 Sacramento JF; Ribeiro MJ; Rodrigues T; Guarino MP; Diogo LN; Seiça R; Monteiro EC; Matafome P; Conde SV. "Insulin resistance is associated with tissue-specific regulation of HIF-1a and HIF-2a during mild chronic intermittent hypoxia.". (2016): http://europepmc.org/abstract/med/26993367. 10.1016/j.resp.2016.03.007 Alvarez-Martins I; Remédio L; Matias I; Diogo LN; Monteiro EC; Dias S; Alvarez-Martins, I.; et al. "The impact of chronic intermittent hypoxia on hematopoiesis and the bone marrow microenvironment.". Pflugers Archiv European Journal of Physiology 468 5 (2016): 919-932. http://europepmc.org/abstract/med/26856724. 10.1007/s00424-016-1797-6 Marinho AT; Dias CG; Pinheiro PF; Lemos AR; Antunes AM; Marques MM; Monteiro EC; Miranda JP; Pereira SA. "Nevirapine modulation of paraoxonase-1 in the liver: An in vitro three-model approach.". (2016): http://europepmc.org/abstract/med/26620700. 10.1016/j.ejps.2015.11.019 Madeira, C.; Pais, A.; Kubiak, C.; Demotes, J.; Monteiro, E.C.. "Investigator-initiated clinical trials conducted by the Portuguese Clinical Research Infrastructure Network (PtCRIN)". Contemporary Clinical Trials Communications 4 (2016): 141-148. http://www.scopus.com/inward/record.url?eid=2-s2.0-84986253551&partnerID=MN8TOARS. 10.1016/j.conctc.2016.08.002 Diogo LN; Pereira SA; Nunes AR; Afonso RA; Santos AI; Monteiro EC. "Efficacy of carvedilol in reversing hypertension induced by chronic intermittent hypoxia in rats.". (2015): http://europepmc.org/abstract/med/26291659. 10.1016/j.ejphar.2015.08.019 Diogo LN; Faustino IV; Afonso RA; Pereira SA; Monteiro EC; Santos AI. "Voluntary Oral Administration of Losartan in Rats.". (2015): http://europepmc.org/abstract/med/26424254. Diogo LN; Pinto P; Bárbara C; Monteiro EC; Papoila AL. "Neck circumference and body mass index as independent predictors of hypertension misclassification in patients suspected of having obstructive sleep apnea.". (2015): http://europepmc.org/abstract/med/25121756. 10.1097/MBP.0000000000000080 Diogo, L.N.; Faustino, I.V.; Afonso, R.A.; Pereira, S.A.; Monteiro, E.C.; Santos, A.I.. "Voluntary oral administration of losartan in rats". Journal of the American Association for Laboratory Animal Science 54 5 (2015): 549-556. http://www.scopus.com/inward/record.url?eid=2-s2.0-84943195739&partnerID=MN8TOARS. Diogo LN; Pinto P; Bárbara C; Papoila AL; Monteiro EC. "The Association Between Antihypertensive Medication and Blood Pressure Control in Patients with Obstructive Sleep Apnea.". (2015): http://europepmc.org/abstract/med/26303482. 10.1007/978-3-319-18440-1_22 Nunes AR; Monteiro E; Gauda E. "Soluble adenylyl cyclase in the locus coeruleus.". (2014): http://europepmc.org/abstract/med/24973474. 10.1016/j.resp.2014.05.011 Grilo NM; Charneira C; Pereira SA; Monteiro EC; Marques MM; Antunes AM. "Bioactivation to an aldehyde metabolite--possible role in the onset of toxicity induced by the anti-HIV drug abacavir.". (2014): http://europepmc.org/abstract/med/24211422. 10.1016/j.toxlet.2013.10.036 Dias C; Marinho A; Morello J; Almeida G; Caixas U; Soto K; Monteiro E; Pereira S. "Monitoring of the lactonase activity of paraoxonase-1 enzyme in HIV-1-infection.". (2014): http://europepmc.org/abstract/PMC/PMC4225321. 10.7448/IAS.17.4.19682 Marinho A; Dias C; Antunes A; Caixas U; Branco T; Marques M; Monteiro E; Pereira S. "Sex differences in apolipoprotein A1 and nevirapine-induced toxicity.". (2014): http://europepmc.org/abstract/med/25394082. 10.7448/IAS.17.4.19575 Nunes AR; Holmes AP; Conde SV; Gauda EB; Monteiro EC. "Revisiting cAMP signaling in the carotid body.". (2014): http://europepmc.org/abstract/med/25389406. 10.3389/fphys.2014.00406 Diogo LN; Monteiro EC. "The efficacy of antihypertensive drugs in chronic intermittent hypoxia conditions.". (2014): http://europepmc.org/abstract/med/25295010. 10.3389/fphys.2014.00361 Conde SV; Sacramento JF; Guarino MP; Gonzalez C; Obeso A; Diogo LN; Monteiro EC; Ribeiro MJ. "Carotid body, insulin, and metabolic diseases: unraveling the links.". (2014): http://europepmc.org/abstract/med/25400585. 10.3389/fphys.2014.00418 Dias, C.G.; Batuca, J.R.; Marinho, A.T.; Caixas, U.; Monteiro, E.C.; Antunes, A.M.M.; Pereira, S.A.. "Quantification of the arylesterase activity of paraoxonase-1 in human blood". Analytical Methods 6 1 (2014): 289-294. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890071175&partnerID=MN8TOARS. 10.1039/c3ay41527a Marinho, A.T.; Godinho, A.L.A.; Novais, D.A.; Antunes, A.M.M.; Marques, M.M.; Ramos, T.; Dias, C.G.; Monteiro, E.C.; Pereira, S.A.. "Development and validation of an HPLC-UV method for quantifying nevirapine and its main phase i metabolites in human blood". Analytical Methods 6 5 (2014): 1575-1580. http://www.scopus.com/inward/record.url?eid=2-s2.0-84894120111&partnerID=MN8TOARS. 10.1039/c3ay41911h Marinho, A. T.; Rodrigues, P. M.; Caixas, U.; Antunes, A. M. M.; Branco, T.; Harjivan, S. G.; Marques, M. M.; Monteiro, E. C.; Pereira, S. A.. "Differences in nevirapine biotransformation as a factor for its sex-dependent dimorphic profile of adverse drug reactions". Journal of Antimicrobial Chemotherapy 69 2 (2013): 476-482. http://dx.doi.org/10.1093/jac/dkt359. 10.1093/jac/dkt359 Ribeiro MJ; Sacramento JF; Gonzalez C; Guarino MP; Monteiro EC; Conde SV. "Carotid body denervation prevents the development of insulin resistance and hypertension induced by hypercaloric diets.". (2013): http://europepmc.org/abstract/med/23530003. 10.2337/db12-1463 Grilo, N.M.; Antunes, A.M.M.; Caixas, U.; Marinho, A.T.; Charneira, C.; Conceição Oliveira, M.; Monteiro, E.C.; Matilde Marques, M.; Pereira, S.A.. "Monitoring abacavir bioactivation in humans: Screening for an aldehyde metabolite". Toxicology Letters 219 1 (2013): 59-64. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875885900&partnerID=MN8TOARS. 10.1016/j.toxlet.2013.02.021 Nunes, A.R.; Holmes, A.P.S.; Sample, V.; Kumar, P.; Cann, M.J.; Monteiro, E.C.; Zhang, J.; Gauda, E.B.. "Bicarbonate-sensitive soluble and transmembrane adenylyl cyclases in peripheral chemoreceptors". Respiratory Physiology and Neurobiology 188 2 (2013): 83-93. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880100523&partnerID=MN8TOARS. 10.1016/j.resp.2013.05.013 Charneira, C.; Grilo, N.M.; Pereira, S.A.; Godinho, A.L.A.; Monteiro, E.C.; Marques, M.M.; Antunes, A.M.M.. "N-terminal valine adduct from the anti-HIV drug abacavir in rat haemoglobin as evidence for abacavir metabolism to a reactive aldehyde in vivo". British Journal of Pharmacology 167 6 (2012): 1353-1361. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867773600&partnerID=MN8TOARS. 10.1111/j.1476-5381.2012.02079.x Nunes AR; Sample V; Xiang YK; Monteiro EC; Gauda E; Zhang J; Nunes, A.R.; et al. "Effect of oxygen on phosphodiesterases (PDE) 3 and 4 isoforms and PKA activity in the superior cervical ganglia.". Advances in Experimental Medicine and Biology 758 (2012): 287-294. http://europepmc.org/abstract/med/23080174. 10.1007/978-94-007-4584-1_39 Conde SV; Obeso A; Monteiro EC; Gonzalez C; Conde, S.V.; Obeso, A.; Monteiro, E.C.; Gonzalez, C.. "Effect of chronic caffeine intake on carotid body catecholamine dynamics in control and chronically hypoxic rats.". Advances in Experimental Medicine and Biology 758 (2012): 315-323. http://europepmc.org/abstract/med/23080178. 10.1007/978-94-007-4584-1_43 Caixas, U.; Antunes, A.M.M.; Marinho, A.T.; Godinho, A.L.A.; Grilo, N.M.; Marques, M.M.; Oliveira, M.C.; et al. "Evidence for nevirapine bioactivation in man: Searching for the first step in the mechanism of nevirapine toxicity". Toxicology 301 1-3 (2012): 33-39. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864807069&partnerID=MN8TOARS. 10.1016/j.tox.2012.06.013 Conde, S.V.; Ribeiro, M.J.; Obeso, A.; Rigual, R.; Monteiro, E.C.; Gonzalez, C.. "Chronic caffeine intake in adult rat inhibits carotid body sensitization produced by chronic sustained hypoxia but maintains intact chemoreflex output". Molecular Pharmacology 82 6 (2012): 1056-1065. http://www.scopus.com/inward/record.url?eid=2-s2.0-84869858797&partnerID=MN8TOARS. 10.1124/mol.112.081216 Conde, S.V.; Nunes Da Silva, T.; Gonzalez, C.; Mota Carmo, M.; Monteiro, E.C.; Guarino, M.P.. "Chronic caffeine intake decreases circulating catecholamines and prevents diet-induced insulin resistance and hypertension in rats". British Journal of Nutrition 107 1 (2012): 86-95. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855787744&partnerID=MN8TOARS. 10.1017/S0007114511002406 Conde, S.V.; Monteiro, E.C.; Rigual, R.; Obeso, A.; Gonzalez, C.. "Hypoxic intensity: A determinant for the contribution of ATP and adenosine to the genesis of carotid body chemosensory activity". Journal of Applied Physiology 112 12 (2012): 2002-2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862579463&partnerID=MN8TOARS. 10.1152/japplphysiol.01617.2011 Pereira, S.A.; Wanke, R.; Marques, M.M.; Monteiro, E.C.; Antunes, A.M.M.. "Insights into the role of bioactivation mechanisms in the toxic events elicited by non-nucleoside reverse transcriptase inhibitors". Advances in Molecular Toxicology 6 (2012): 1-39. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865355478&partnerID=MN8TOARS. 10.1016/B978-0-444-59389-4.00001-X Caixas, U.; Ferreira, J.; Marinho, A.T.; Faustino, I.; Grilo, N.M.; Lampreia, F.; Germano, I.; Monteiro, E.C.; Pereira, S.A.. "Long-term maraviroc use as salvage therapy in HIV-2 infection". Journal of Antimicrobial Chemotherapy 67 10 (2012): 2538-2539. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866613168&partnerID=MN8TOARS. 10.1093/jac/dks240 Monteiro, T.C.; Batuca, J.R.; Obeso, A.; González, C.; Monteiro, E.C.. "Carotid body function in aged rats: Responses to hypoxia, ischemia, dopamine, and adenosine". Age 33 3 (2011): 337-350. http://www.scopus.com/inward/record.url?eid=2-s2.0-80655145960&partnerID=MN8TOARS. 10.1007/s11357-010-9187-z Charneira, C.; Godinho, A.L.A.; Oliveira, M.C.; Pereira, S.A.; Monteiro, E.C.; Marques, M.M.; Antunes, A.M.M.. "Reactive aldehyde metabolites from the anti-HIV drug abacavir: Amino acid adducts as possible factors in abacavir toxicity". Chemical Research in Toxicology 24 12 (2011): 2129-2141. http://www.scopus.com/inward/record.url?eid=2-s2.0-84055218870&partnerID=MN8TOARS. 10.1021/tx200337b Nunes, A.R.; Batuca, J.R.; Monteiro, E.C.. "Acute hypoxia modifies cAMP levels induced by inhibitors of phosphodiesterase-4 in rat carotid bodies, carotid arteries and superior cervical ganglia". British Journal of Pharmacology 159 2 (2010): 353-361. http://www.scopus.com/inward/record.url?eid=2-s2.0-75649134184&partnerID=MN8TOARS. 10.1111/j.1476-5381.2009.00534.x Pereira, S. A.; Batuca, J. R.; Caixas, U.; Branco, T.; Delgado-Alves, J.; Germano, I.; Lampreia, F.; Monteiro, E. C.. "Effect of efavirenz on high-density lipoprotein antioxidant properties in HIV-infected patients". British Journal of Clinical Pharmacology 68 6 (2009): 891-897. http://dx.doi.org/10.1111/j.1365-2125.2009.03535.x. 10.1111/j.1365-2125.2009.03535.x Conde, S.V.; Obeso, A.; Monteiro, E.C.; Gonzalez, C.. "The A 2B-D 2 receptor interaction that controls carotid body catecholamines release locates between the last two steps of hypoxic transduction cascade". Advances in Experimental Medicine and Biology 648 (2009): 161-168. http://www.scopus.com/inward/record.url?eid=2-s2.0-67651205673&partnerID=MN8TOARS. 10.1007/978-90-481-2259-2_18 Conde, S.V.; Monteiro, E.C.; Obeso, A.; Gonzalez, C.. "Adenosine in peripheral chemoreception: New insights into a historically overlooked molecule". Advances in Experimental Medicine and Biology 648 (2009): 145-159. http://www.scopus.com/inward/record.url?eid=2-s2.0-67651205671&partnerID=MN8TOARS. 10.1007/978-90-481-2259-2_17 Nunes, A.R.; Batuca, J.R.; Monteiro, E.C.. "Functional characterization of phosphodiesterases 4 in the rat carotid body: Effect of oxygen concentrations". Advances in Experimental Medicine and Biology 648 (2009): 113-119. http://www.scopus.com/inward/record.url?eid=2-s2.0-67651219181&partnerID=MN8TOARS. 10.1007/978-90-481-2259-2_13 Nunes, A.R.; Monteiro, E.C.; Johnson, S.M.; Gauda, E.B.. "Bicarbonate-regulated soluble adenylyl cyclase (sAC) mRNA expression and activity in peripheral chemoreceptors". Advances in Experimental Medicine and Biology 648 (2009): 235-241. http://www.scopus.com/inward/record.url?eid=2-s2.0-67651207741&partnerID=MN8TOARS. 10.1007/978-90-481-2259-2_27 Monteiro, T.C.; Obeso, A.; Gonzalez, C.; Monteiro, E.C.. "Does ageing modify ventilatory responses to dopamine in anaesthetised rats breathing spontaneously?". Advances in Experimental Medicine and Biology 648 (2009): 265-271. http://www.scopus.com/inward/record.url?eid=2-s2.0-67651205663&partnerID=MN8TOARS. 10.1007/978-90-481-2259-2_30 Pereira, S.A.; Branco, T.; Caixas, U.; Côrte-Real, R.M.; Germano, I.; Lampreia, F.; Monteiro, E.C.. "Intra-individual variability in efavirenz plasma concentrations supports therapeutic drug monitoring based on quarterly sampling in the first year of therapy". Therapeutic Drug Monitoring 30 1 (2008): 60-66. http://www.scopus.com/inward/record.url?eid=2-s2.0-38549087038&partnerID=MN8TOARS. 10.1097/FTD.0b013e318160ce76 Pereira, S.A.; Caixas, U.; Branco, T.; Germano, I.; Lampreia, F.; Papoila, A.L.; Monteiro, E.C.. "Efavirenz concentrations in HIV-infected patients with and without viral hepatitis". British Journal of Clinical Pharmacology 66 4 (2008): 551-555. http://www.scopus.com/inward/record.url?eid=2-s2.0-51649096977&partnerID=MN8TOARS. 10.1111/j.1365-2125.2008.03238.x Conde, S.V.; Gonzalez, C.; Batuca, J.R.; Monteiro, E.C.; Obeso, A.. "An antagonistic interaction between A2B adenosine and D 2 dopamine receptors modulates the function of rat carotid body chemoreceptor cells". Journal of Neurochemistry 107 5 (2008): 1369-1381. http://www.scopus.com/inward/record.url?eid=2-s2.0-55849129304&partnerID=MN8TOARS. 10.1111/j.1471-4159.2008.05704.x Conde, S.V.; Monteiro, E.C.. "Activation of nicotinic ACh receptors with a4 subunits induces adenosine release at the rat carotid body". British Journal of Pharmacology 147 7 (2006): 783-789. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645547406&partnerID=MN8TOARS. 10.1038/sj.bjp.0706676 Pereira, S.A.; Branco, T.; Côrte-Real, R.M.; Germano, I.; Lampreia, F.; Caixas, U.; Monteiro, E.C.. "Long-term and concentration-dependent beneficial effect of efavirenz on HDL-cholesterol in HIV-infected patients". British Journal of Clinical Pharmacology 61 5 (2006): 601-604. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646265773&partnerID=MN8TOARS. 10.1111/j.1365-2125.2006.02619.x Conde, S.V.; Obeso, A.; Rigual, R.; Monteiro, E.C.; Gonzalez, C.. "Function of the rat carotid body chemoreceptors in ageing". Journal of Neurochemistry 99 3 (2006): 711-723. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750080433&partnerID=MN8TOARS. 10.1111/j.1471-4159.2006.04094.x Conde SV; Monteiro EC. "Profiles for ATP and adenosine release at the carotid body in response to O2 concentrations.". (2006): http://europepmc.org/abstract/med/16683716. Conde, S.V.; Monteiro, E.C.. "Profiles for ATP and adenosine release at the carotid body in response to O2 concentrations.". Advances in experimental medicine and biology. 580 (2006): http://www.scopus.com/inward/record.url?eid=2-s2.0-33745233081&partnerID=MN8TOARS. Conde, S.V.; Monteiro, E.C.. "Profiles for ATP and adenosine release at the carotid body in response to O2 concentrations". Advances in Experimental Medicine and Biology 580 (2006): 179-184. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745233081&partnerID=MN8TOARS. 10.1007/0-387-31311-7-27 Conde, S.V.; Monteiro, E.C.. "Hypoxia induces adenosine release from the rat carotid body". Journal of Neurochemistry 89 5 (2004): 1148-1156. http://www.scopus.com/inward/record.url?eid=2-s2.0-2642526852&partnerID=MN8TOARS. 10.1111/j.1471-4159.2004.02380.x Batuca JR; Monteiro TC; Monteiro EC. "Contribution of dopamine D2 receptors for the cAMP levels at the carotid body.". (2003): http://europepmc.org/abstract/med/14635690. Conde SV; Monteiro EC. "Adenosine-acetylcholine interactions at the rat carotid body.". (2003): http://europepmc.org/abstract/med/14635682. Conde, S.V.; Monteiro, E.C.. "Adenosine-Acetylcholine Interactions at the Rat Carotid Body". Advances in Experimental Medicine and Biology 536 (2002): 305-311. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344688361&partnerID=MN8TOARS. Batuca, J.R.; Monteiro, T.C.; Monteiro, E.C.. "Contribution of Dopamine D2 Receptors for the cAMP Levels at the Carotid Body". Advances in Experimental Medicine and Biology 536 (2002): 367-373. http://www.scopus.com/inward/record.url?eid=2-s2.0-3543138433&partnerID=MN8TOARS. Monteiro EC; Ribeiro JA. "Adenosine-dopamine interactions and ventilation mediated through carotid body chemoreceptors.". (2000): http://europepmc.org/abstract/med/10849708. Monteiro, E.C.; Ribeiro, J.A.. "Adenosine-dopamine interactions and ventilation mediated through carotid body chemoreceptors". Advances in Experimental Medicine and Biology 475 (2000): 671-684. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034465679&partnerID=MN8TOARS. Monteiro EC; Vera-Cruz P; Monteiro TC; Silva e Sousa MA. "Adenosine increases the cAMP content of the rat carotid body in vitro.". (1996): http://europepmc.org/abstract/med/9030315. Monteiro, E.C.; Vera-Cruz, P.; Monteiro, T.C.; Silva E Sousa, M.A.. "Adenosine increases the cAMP content of the rat carotid body in vitro". Advances in Experimental Medicine and Biology 410 (1996): 299-303. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030452543&partnerID=MN8TOARS. Monteiro EC; Ribeiro JA; Monteiro, E.C.; Ribeiro, J.A.. "Adenosine and the bradycardiac response to vagus nerve stimulation in rats.". European Journal of Pharmacology 204 2 (1991): 193-202. http://europepmc.org/abstract/med/1806387. 10.1016/0014-2999(91)90705-U Monteiro, E.C.; Ribeiro, J.A.. "Involvement of adenosine during stimulation of ventilation induced by common carotid occlusion". Revista Portuguesa de Hemorreologia 5 2 (1991): 249-254. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025950467&partnerID=MN8TOARS. Ribeiro, J.A.; Monteiro, E.C.. "On the adenosine receptor involved in the excitatory action of adenosine on respiration: Antagonist profile". Nucleosides and Nucleotides 10 5 (1991): 945-953. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026005936&partnerID=MN8TOARS. 10.1080/07328319108047232 Monteiro EC; Ribeiro JA; Monteiro, E.C.; Ribeiro, J.A.. "Adenosine deaminase and adenosine uptake inhibitions facilitate ventilation in rats.". Naunyn-Schmiedeberg's Archives of Pharmacology 340 2 (1989): 230-238. http://europepmc.org/abstract/med/2812035. 10.1007/BF00168974 Monteiro, E.C.; Ribeiro, J.A.; Monteiro EC; Ribeiro JA. "Inhibition by 1,3-dipropyl-8(p-sulfophenyl)xanthine of the respiratory stimulation induced by common carotid occlusion in rats". Life Sciences 45 10 (1989): 939-945. http://www.scopus.com/inward/record.url?eid=2-s2.0-0024453848&partnerID=MN8TOARS. 10.1016/0024-3205(89)90208-7 Monteiro, E.C.; Ribeiro, J.A.; Monteiro EC; Ribeiro JA. "Ventilatory effects of adenosine mediated by carotid body chemoreceptors in the rat". Naunyn-Schmiedeberg's Archives of Pharmacology 335 2 (1987): 143-148. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023102955&partnerID=MN8TOARS. 10.1007/BF00177715
Capítulo de livro	Gonçalves-Dias, Clara; Sequeira, Catarina O.; Vicente, João B.; Correia, M. João; Coelho, Nuno R.; Morello, Judit; Antunes, Alexandra M. M.; et al. "A Mechanistic-Based and Non-invasive Approach to Quantify the Capability of Kidney to Detoxify Cysteine-Disulfides". In Advances in Experimental Medicine and Biology, 109-120. Springer International Publishing, 2021. Publicado • 10.1007/978-3-030-63908-2_8 Isabel Faro de Albuquerque; Catarina Martins Lopes; Nuno Lourenço-Silva; José Fragata; Monteiro, EC. "Which medical professional?". In From Life Molecules to Global Health, 620-632. PRINCIPIA, 2021. Publicado João Filipe Raposo; José A. Belo; Sílvia V. Conde; Monteiro, EC; José Silva Nunes; Pereira, Sofia A.; Gabriela A. Silva; Maria Paula Macedo. "B FROM A CLASSICAL TO A NEW NOVA PERSPECTIVE ON CARDIOMETABOLIC DISEASES". In From Life Molecules to Global Health, 261-290. PRINCIPIA, 2021. Publicado Coelho, Nuno R.; Dias, Clara G.; João Correia, M.; Grácio, Patrícia; Serpa, Jacinta; Monteiro, Emília C.; Diogo, Lucília N.; Pereira, Sofia A.. "Cysteine Oxidative Dynamics Underlies Hypertension and Kidney Dysfunction Induced by Chronic Intermittent Hypoxia". In Advances in Experimental Medicine and Biology, 83-88. Springer International Publishing, 2018. 10.1007/978-3-319-91137-3_10 Monteiro, EC. "Understanding the molecular basis for the hazards associated with Nevirapine treatment". In Advances in Medicine and Biology, 77-100. Nova Science Publishers, 2012. CONDE, SÍLVIA V.; MONTEIRO, EMÍLIA C.. "Profiles for ATP and Adenosine Release at the Carotid Body in Response to O2 Concentrations". In ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, 179-184. Springer US, 2006. 10.1007/0-387-31311-7_27 Monteiro, EC. "Perfil Farmacológico dos fármacos agonistas dos receptores B2. Em: Agonistas dos receptores B2". In Curso Interactivo de Pneumologia, 719. Permanyer Portugal, 2002. Monteiro, EC. "Endogenous adenosine tonically excites respiration mediated through carotid body chemoreceptors in the rat". In Arterial Chemoreception, 174-180. Springer Verlag, New York, 1990. Monteiro, EC. "Respiratory responses to common carotid occlusion in the rat: evidence for involvement of adenosine". In Chemoreceptors and Chemoreceptor reflexes, 49-56. Plenum Press, New York, 1990. Monteiro, EC. "The actions of adenosine on respiration". In Physiology and Pharmacology of Adenosine and Adenine nucleotides, 225-232. Taylor and Francis, Ltd, London, 1988. Monteiro, EC. "Adenosine modulation of respiration mediated by carotid body chemoreceptors". In Chemoreceptors and Respiratory Control, 314-320. Croom Helm, London, 1987. Monteiro, EC. "Fisiologia de la Tos". In Libro de Homenaje al Prof. Ortiz de Landazuri. Garsi, Madrid, 1984.
Poster em conferência	Monteiro, EC; Coelho, Nuno; Tomkiewcz, Céline; Correia, M João; Pimpão, António; Barouki, Robert; Coumoul, Xavier; Pereira, Sofia A.. "P19-ARYL HYDROCARBON RECEPTOR ANTAGONISTS - A NEW ENTRY IN ANTIHYPERTENSIVE ARMAMENTARIUM OF OBSTRUCTIVE SLEEP APNEA?". Trabalho apresentado em ESH-ISH Joint Meeting - Hypertension meeting participation, 2021.
Recurso online	Monteiro, EC. Layman summary: Zebrafish is an attractive model to anticipate drug-induced renal injury in humans. 2018. http://atlasofscience.org/zebrafish-is-an-attractive-model-to-anticipate-drug-induced-renal-injury-in-humans/.
Relatório	2022. Immunisation for old adults in Europe: scientific and social strategies. https://www.feam.eu/feam-publications/.
Resumo em conferência	Monteiro, EC. "Metabolomics of drug-induced renal injury in zebrafishlarvae [oral presentation]". Trabalho apresentado em XLVII meeting of thePortugueseSociety of Pharmacology, 2018. Monteiro, EC. "Is zebrafish a good model to assess drug-inducedrenalinjury? [inivited oral presentation]". Trabalho apresentado em 3rd International Conference on Urine Omics and 2nd International CaparicaConference inTranslational Nephrology, 2017. Monteiro, EC. "Molecular targeting of proteins by homocysteine inhypercholesterolemia [oral presentation]". Trabalho apresentado em XLVI ReuniãoAnual da Sociedade Portuguesa de Farmacologia/ XXXIII Reunião deFarmacologia Clínica/ XV Reunião de Toxicologia, 2016. Monteiro, EC. "Modulation of paraoxonase-1 by nevirapine: comparisonbetween three in vitro models [oral presentation]". Trabalho apresentado em XLVIReunião Anual da Sociedade Portuguesa de Farmacologia/ XXXIII Reunião deFarmacologia Clínica/ XV Reunião de Toxicologia, 2016. Monteiro, EC. "Urinary N-acetylated cysteine-disulfides as indicators ofkidney disease progression in HIV-infected patients [oral presentation]". Trabalho apresentado em 7th European Congress of Pharmacology (EPHAR), 2016. Monteiro, EC. "Monitoring glomerular function in zebrafish larvae (Daniorerio) exposed to nephrotoxic drugs. [oral presentation]". Trabalho apresentado em XLV meeting of the Portuguese Society of Pharmacology, 2015. Monteiro, EC. "The role of Nevirapine phase I metabolites in the renalfunction of HIV-infected patients [oral presentation]". Trabalho apresentado em 1stInternational Caparica Conference in Translational Nephrology & 18thPortuguese Symposium on Renal Diseases, 2014. Monteiro, EC. "Antivíricos diretos e imunossupressores: interações [invitedoral presentation]". Trabalho apresentado em Workshop Hepatite C - InovaçãoFarmacologia e Transplantação, 2014. Monteiro, EC. "Relevance of CYP2C19 genotypes in Nevirapinebiotransformation [oral presentation]". Trabalho apresentado em European Society ofPharmacogenomics and Theranostics (ESPT) Second Conference.Pharmacogenomics: from Cell to Clinic, 2013. Monteiro, EC. "Effect of chronic exposure to the antiretroviral drugnevirapine on paraoxonase-1 activities in HIV-infected patients [oralpresentation]". Trabalho apresentado em 2nd International Conference onOccupational & Environmental Toxicology, 2013. Monteiro, EC. "Biomedical models for translational research [invited oralpresentation]". Trabalho apresentado em 3º Congresso Internacional de Enfermagem Veterinária, 2013. Monteiro, EC. "Hemoglobin adducts from the antiretroviralabacavir in HIV-infected patients as evidence of bioactivation [oralpresentation]". Trabalho apresentado em 244th ACS National Meeting & Exposition, Philadelphia, 2012.

Propriedade Intelectual

Patente

Monteiro, EC. 2019. "2-hydroxy-nevirapine analogues or derivatives for use in the treatment of diseases related to high density lipoprotein dysfunction. PPI 2019/20066".

Outros

Outra produção

Investigator initiated clinical trials (IICTs): a systematic search in registries comparing Czech Republic and Portugal in terms of funding policies and scientific outcomes. 2020. Catarina Madeira; Lenka Horavová; Francisco dos Santos; Joana Batuca; Katerina Nebeska; Lenka Souckova; Christine Kubiak; et al. https://doi.org/10.21203/rs.2.24789/v1.
10.21203/rs.2.24789/v1

Atividades

Apresentação oral de trabalho

	Título da apresentação	Nome do evento Anfitrião (Local do evento)
2021/04/29	Phenotyping SULT in Man: a Simple Metric Using Paracetamol as Probe (R3064 poster)	ASPET Annual Meeting at EB 2021

Orientação

	Título / Tema Papel desempenhado	Curso (Tipo) Instituição / Organização
2016 - 2020	ARYL HYDROCARBON RECEPTOR (AHR): A THERAPEUTIC TARGET FOR SYSTEMIC HYPERTENSION ASSOCIATED WITH CHRONIC INTERMITTENT HYPOXIA Orientador	Doutor em Mecanismos de Doença e Medicina Regenerativa (Doutoramento) Universidade Nova de Lisboa, Portugal
2014 - 2019	The multimorbidity of asthma and rhinitis: from epidemiologic data to molecular traits Coorientador	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2014 - 2018	Teaching an old drug new tricks: reprofiling of nevirapine as an HDL modulator Coorientador	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2010 - 2015	Evaluation of antihypertensive drugs in patients with obstructive sleep apnea and in rat s submitted to chronic intermittent hypoxia Coorientador	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2010 - 2014	New insights for understanding postoperative cognitive dysfunction Coorientador	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2009 - 2013	O2/CO2sensitive cAMP signaling pathway in peripher al chemoreceptors Coorientador	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2005 - 2011	Functional evaluation of carotid body in ageing Orientador	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2006 - 2010	Therapeutic drug monitoring of efavirenz in clinical practice and long term effects of the drug Orientador	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2003 - 2007	Functional significance of adenosine receptors in carotid body chemosensory activity in control and chronically hypoxic animals Orientador	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Organização de evento

	Nome do evento Tipo de evento (Tipo de participação)	Instituição / Organização
2022/06/27 - 2022/06/30	Organization of the Meeting of the International Society for Arterial Chemoreception (2022/06/27 - 2022/06/30) Encontro	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2014 - 2015	Organization of the Meeting of the Portguese Society of Pharmacology 2015 (2015 - 2015) Encontro	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Participação em evento

	Descrição da atividade Tipo de evento	Nome do evento Instituição / Organização
2021/11/09 - Atual	Roundtable ´´Training of Clinical Research Centers in Portugal``: How to promote quality, efficiency and cooperation? Mesa-redonda	Prémios AICIB 2021
2010 - Atual	Pariticipation in the OPEN DAYS of the institute (outreach activities). Outro	OPEN DAYS CEDOC \| FCM Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2022/01/31 - 2022/01/31	How should Europe prepare and respond to cross-border health threats: HERA? Oficina (workshop)	How should Europe prepare and respond to cross-border health threats: HERA? Federation of European Academies of Medicine, FEAM, Bélgica
2021/02/18 - 2021/02/18	Chair at CLINICAL PHARMACOLOGY II session Encontro	SPF Meeting 2021 Universidade de Lisboa Faculdade de Farmácia, Portugal Sociedade Portuguesa de Farmacologia, Portugal
2021/02/17 - 2021/02/17	ROUNDTABLE member: Teaching Pharmacology, Therapeutics and Toxicology Encontro	SPF Meeting 2021 Universidade de Lisboa Faculdade de Farmácia, Portugal Sociedade Portuguesa de Farmacologia, Portugal

Júri de grau académico

	Tema Tipo de participação	Nome do candidato (Tipo de grau) Instituição / Organização
2021/12/20	"Targeting the carotid bodies to treat obesity" Presidente do júri	Bernardete Sofia Freitas de Melo (Doutoramento) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Comissão de avaliação

	Descrição da atividade Tipo de assessoria	Instituição / Organização	Entidade financiadora
2018 - 2018	Member of the evaluation panel of the research grants supported by the "Agence Nationale de Sécurité du Medicament et des Produits de Santé" Membro	Agence nationale de sécurité du médicament et des produits de santé, França
2010 - 2017	Evaluator of research grants and scientific projects at Foundation for Science and Technology, Portuguese Ministry of Education and Science Avaliador	Fundação para a Ciência e a Tecnologia, Portugal

Consultoria / Parecer

	Descrição da atividade	Instituição / Organização
2018 - Atual	iNOVA4Health Management Board	Universidade Nova de Lisboa, Portugal

Curso / Disciplina lecionado

	Disciplina	Curso (Tipo)	Instituição / Organização
2019 - Atual	Curricular Unit Core Methodologies in Research.	Ciências da Saúde (Doutoramento)	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019 - Atual	Chair of the Curricular Unit Core Methodologies in Biomedical and Clinical Research, PhD Program in Health Sciences	(Doutoramento)	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019 - Atual	Chair of the Curricular Unit Pathophysiology and Therapeutic Targets, Integrated Master in Medicine	(Mestrado integrado)	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2012 - Atual	Nuclear Curricular Unit of Phatophysiology and Therapeutic Targets	Medicina (Mestrado integrado)	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2022 - 2022	Module 6 - Exploratory Development (Molecule for Proof of Concept)	(Pós-Graduação)	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2022 - 2022	Module 4 - Non-Clinical Tests	(Pós-Graduação)	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2017 - 2020	Chair of the Curricular Unit Medical Devices, Integrated Master in Medicine	Medicina (Mestrado integrado)	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2013 - 2018	Chair of the Curricular Units Pharmacology and/or General Pharmacology, Integrated Master of Medicine	Medicina (Mestrado integrado)	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2003 - 2018	Curricular units Pharmacology and/or General Pharmacology	Medicina (Mestrado integrado)	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Membro de associação

	Nome da associação	Tipo de participação
2021 - Atual	CoLAB trials, Nova Medical School	Representative
2019 - Atual	Full member of the Portuguese Academy of Medicine
2017 - 2020	President of the International Society for Arterial Chemoreception (ISAC)	Presdent
2016 - 2018	Correspondent member of the Portuguese Academy of Medicine	Correspondent Member
2009 - 2017	Society of Medical Sciences of Lisbon	Member of the Direction
2009 - 2013	President of the Portuguese Society of Pharmacology and Clinical Pharmacology	President

Membro de comissão

	Descrição da atividade Tipo de participação	Instituição / Organização
2021 - Atual	Council Member, Portuguese Academy of Medicine representative Membro	Federation of European Academies of Medicine, FEAM, Bélgica
2020 - Atual	Member of the executive board of CEDOC (CENTRO DE ESTUDOS DE DOENÇAS CRÓNICAS) Membro	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2018 - Atual	External advisor of the Scientific Committee of the Spanish Clinical Research Network ISCIII Consultor	Instituto de Salud Carlos III, Espanha
2014 - Atual	Member of the Network Committee Membro	European Clinical Research Infrastructure Network, França
2013 - Atual	Member of the scientific council of the “Agence Nationale de Sécurité du Medicament et des Produits de Santé” Membro	Agence nationale de sécurité du médicament et des produits de santé, França
2013 - Atual	Member of the Scientific Council Membro	Agence nationale de sécurité du médicament et des produits de santé, França
2013 - Atual	Senior Clinical and Scientific lead of the academic clinical trial unit NOVACRU Outro	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2009 - Atual	Member of the National Ethics Committee for Clinical Research (CEIC). Evaluator of Clinical trials Membro	Comissão de Ética para a Investigação Clínica, Portugal
2009 - Atual	Member Membro	CEIC, Comissão de Ética para a Investigação Clínica, Portugal
2017 - 2020	Vice-chair of the ECRIN-ERIC steering committee (European Clinical Research Infrastructure Network/ European Research Infrastructures Consortium)
2013 - 2018	Member of the pedagogic council of the Nova Medical School	Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2017 - 2017	Preparation of the Portuguese Strategic Agenda for Research and Innovation in Health. Membro
2013 - 2014	Delegate of Portugal in the FP 7 and Horizon 2020- topic, SC1 "Health, demographic change and wellbeing"
2010 - 2011	Collaborator in the preparation of Portuguese National Health Programme 2011-2016 in the area of drugs, technologies and medical devices