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Identificação

Identificação pessoal

Nome completo
Ricardo Lagoa

Identificadores de autor

Ciência ID
5C18-A29A-44AB
ORCID iD
0000-0003-2375-6612
Researcher Id
AEV-0520-2022
Scopus Author Id
23051352300
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2011/11/29 - Atual Professor Adjunto (Docente Ensino Superior Politécnico) Instituto Politécnico de Leiria Escola Superior de Tecnologia e Gestão, Portugal
2000/10/01 - 2011/11/28 Assistente (Docente Ensino Superior Politécnico) Instituto Politécnico de Leiria, Portugal
Projetos

Projeto

Designação Financiadores
2018/10/01 - 2022/09/30 Multifunctional biomolecular systems for new methods of decontamination, protection and toxicological assessment
PTDC/BIA-MIB/31864/2017
Investigador responsável
Instituto Politécnico de Leiria, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Marques-da-Silva, Dorinda; Mal, Sib Sankar; Aureliano, Manuel; Lagoa, Ricardo. "The Growth Curve Method to Rapidly Derive the Antibacterial Potential of Polyoxovanadates". Trabalho apresentado em Biosystems in Toxicology and Pharmacology – Current Challenges (BiTaP 2022), 2022.
    Publicado • 10.3390/bitap-12790
  2. Silva, João; Videira, Paula Alexandra Quintela; Lagoa, Ricardo. "Bioactivity gradients of cytoprotective and anticancer catechins in skin: Simulation studies for the design of controlled release systems". Trabalho apresentado em 5th Portuguese Meeting on Bioengineering, Coimbra, 2017.
    Publicado • 10.1109/enbeng.2017.7889467
  3. Mendes, Ausenda; Lagoa, Ricardo; Bártolo, Paulo. "Rapid prototyping system for tissue engineering". Trabalho apresentado em 1st International Conference on Advanced Research on Virtual and Rapid Prototyping, 2003.
    Publicado
Artigo em revista
  1. Matin, Maima; Yeung, Andy Wai Kan; Joshi, Tanuj; Tzvetkov, Nikolay T.; Matin, Farhan Bin; Strzalkowska, Nina; Ksepka, Natalia; et al. "Ginger: a total-scale analysis of the scientific literature on a widely used spice and phytotherapeutic". Animal Science Papers and Reports 42 4 (2024): 349-364. https://doi.org/10.2478/aspr-2023-0042.
    10.2478/aspr-2023-0042
  2. Lopes, João; Marques-da-Silva, Dorinda; Videira, Paula A.; Samhan-Arias, Alejandro K.; Lagoa, Ricardo. "Cardiolipin Membranes Promote Cytochrome c Transformation of Polycyclic Aromatic Hydrocarbons and Their In Vivo Metabolites". Molecules 29 5 (2024): 1129. https://doi.org/10.3390/molecules29051129.
    10.3390/molecules29051129
  3. Ruszkowska-Ciastek, Barbara; Kwiatkowska, Katarzyna; Marques-da-Silva, Dorinda; Lagoa, Ricardo. "Cancer Stem Cells from Definition to Detection and Targeted Drugs". International Journal of Molecular Sciences 25 7 (2024): 3903. https://doi.org/10.3390/ijms25073903.
    10.3390/ijms25073903
  4. López-Sánchez, Carmen; Lagoa, Ricardo; Poejo, Joana; García-López, Virginio; García-Martínez, Virginio; Gutierrez-Merino, Carlos. "An Update of Kaempferol Protection against Brain Damage Induced by Ischemia-Reperfusion and by 3-Nitropropionic Acid". Molecules 29 4 (2024): 776. http://dx.doi.org/10.3390/molecules29040776.
    10.3390/molecules29040776
  5. Marques-da-Silva, Dorinda; Lagoa, Ricardo. "Rafting on the Evidence for Lipid Raft-like Domains as Hubs Triggering Environmental Toxicants’ Cellular Effects". Molecules 28 18 (2023): 6598. http://dx.doi.org/10.3390/molecules28186598.
    10.3390/molecules28186598
  6. Pal, Dilipkumar; Raj, Khushboo; Nandi, Shyam Sundar; Sinha, Surajit; Mishra, Abhishek; Mondal, Arijit; Lagoa, Ricardo; Burcher, Jack T.; Bishayee, Anupam. "Potential of Synthetic and Natural Compounds as Novel Histone Deacetylase Inhibitors for the Treatment of Hematological Malignancies". Cancers 15 10 (2023): 2808. http://dx.doi.org/10.3390/cancers15102808.
    10.3390/cancers15102808
  7. Ghanbari-Movahed, Maryam; Shafiee, Sahar; Burcher, Jack T.; Lagoa, Ricardo; Farzaei, Mohammad Hosein; Bishayee, Anupam. "Anticancer Potential of Apigenin and Isovitexin with Focus on Oncogenic Metabolism in Cancer Stem Cells". Metabolites 13 3 (2023): 404. http://dx.doi.org/10.3390/metabo13030404.
    10.3390/metabo13030404
  8. Arunachalam, Kannappan; Pandurangan, Poonguzhali; Shi, Chunlei; Lagoa, Ricardo. "Regulation of Staphylococcus aureus Virulence and Application of Nanotherapeutics to Eradicate S. aureus Infection". Pharmaceutics 15 2 (2023): 310. http://dx.doi.org/10.3390/pharmaceutics15020310.
    10.3390/pharmaceutics15020310
  9. Marques-da-Silva, Dorinda; Lopes, João M.; Correia, Iris; Silva, João S.; Lagoa, Ricardo. "Removal of Hydrophobic Organic Pollutants and Copper by Alginate-Based and Polycaprolactone Materials". Processes 10 11 (2022): 2300. http://dx.doi.org/10.3390/pr10112300.
    Acesso aberto • 10.3390/pr10112300
  10. Lopes, João M.; Marques-da-Silva, Dorinda; Videira, Paula Q.; Lagoa, Ricardo L.. Autor correspondente: Lagoa, Ricardo L.. "Comparison of Laccases and Hemeproteins Systems in Bioremediation of Organic Pollutants". Current Protein & Peptide Science 23 6 (2022): 402-423. http://dx.doi.org/10.2174/1389203723666220704090416.
    10.2174/1389203723666220704090416
  11. Renu, Kaviyarasi; Mukherjee, Anirban Goutam; Wanjari, Uddesh Ramesh; Vinayagam, Sathishkumar; Veeraraghavan, Vishnu Priya; Vellingiri, Balachandar; George, Alex; et al. "Misuse of Cardiac Lipid upon Exposure to Toxic Trace Elements - A Focused Review". Molecules 27 17 (2022): 5657. http://dx.doi.org/10.3390/molecules27175657.
    10.3390/molecules27175657
  12. Marques-da-Silva, Dorinda; Videira, Paula Alexandra; Lagoa, Ricardo. "Registered human trials addressing environmental and occupational toxicant exposures: Scoping review of immunological markers and protective strategies". Environmental Toxicology and Pharmacology 93 (2022): 103886. http://dx.doi.org/10.1016/j.etap.2022.103886.
    Acesso aberto • 10.1016/j.etap.2022.103886
  13. Lagoa, Ricardo; Marques-da-Silva, Dorinda; Diniz, Mário; Daglia, Maria; Bishayee, Anupam. Autor correspondente: Lagoa, Ricardo. "Molecular mechanisms linking environmental toxicants to cancer development: Significance for protective interventions with polyphenols". Seminars in Cancer Biology 80 (2022): 118-144. http://dx.doi.org/10.1016/j.semcancer.2020.02.002.
    10.1016/j.semcancer.2020.02.002
  14. Silva, João; Marques-da-Silva, Dorinda; Lagoa, Ricardo. Autor correspondente: Lagoa, Ricardo. "Reassessment of the experimental skin permeability coefficients of polycyclic aromatic hydrocarbons and organophosphorus pesticides". Environmental Toxicology and Pharmacology 86 (2021): 103671. http://dx.doi.org/10.1016/j.etap.2021.103671.
    10.1016/j.etap.2021.103671
  15. Silva, João; Vanat, Pavlo; Dorinda Marques-da-Silva; Rodrigues, Joaquim; Lagoa, Ricardo. Autor correspondente: Lagoa, Ricardo. "Metal alginates for polyphenol delivery systems: Studies on crosslinking ions and easy-to-use patches for release of protective flavonoids in skin". Bioactive Materials 5 3 (2020): 447-457. http://dx.doi.org/10.1016/j.bioactmat.2020.03.012.
    Acesso aberto • 10.1016/j.bioactmat.2020.03.012
  16. Kannappan, Arunachalam; Durgadevi, Ravindran; Srinivasan, Ramanathan; Lagoa, Ricardo; Packiavathy, Issac Abraham Sybiya Vasantha; Pandian, Shunmugiah Karutha; Veera Ravi, Arumugam. "2-Hydroxy-4-methoxybenzaldehyde from Hemidesmus indicus is antagonistic to Staphylococcus epidermidis biofilm formation". Biofouling 36 5 (2020): 549-563. http://dx.doi.org/10.1080/08927014.2020.1777989.
    10.1080/08927014.2020.1777989
  17. Lagoa, Ricardo; Silva, João; Rodrigues, Joaquim; Anupam Bishayee. Autor correspondente: Lagoa, Ricardo. "Advances in phytochemical delivery systems for improved anticancer activity". Biotechnology Advances 38 (2020): https://doi.org/10.1016/j.biotechadv.2019.04.004.
    10.1016/j.biotechadv.2019.04.004
  18. Kim, Doo Hwan; Khan, Haroon; Ullah, Hammad; Hassan, Sherif T.S.; Šmejkal, Karel; Efferth, Thomas; Mahomoodally, Mohamad Fawzi; et al. "MicroRNA targeting by quercetin in cancer treatment and chemoprotection". Pharmacological Research 147 (2019): 104346. http://dx.doi.org/10.1016/j.phrs.2019.104346.
    Publicado • 10.1016/j.phrs.2019.104346
  19. Rengasamy, K.R.R.; Khan, H.; Gowrishankar, S.; Lagoa, Ricardo; Mahomoodally, F.M.; Khan, Z.; Suroowan, S.; et al. "The role of flavonoids in autoimmune diseases: Therapeutic updates". Pharmacology and Therapeutics 194 (2019): 107-131. https://doi.org/10.1016/j.pharmthera.2018.09.009.
    Publicado • 10.1016/j.pharmthera.2018.09.009
  20. Silva, Dorinda; Gil Fraqueza; Lagoa, Ricardo; Anjana Anandan Vannathan; Sib Sankar Mal; Manuel Aureliano. "Polyoxovanadate inhibition of Escherichia coli growth shows a reverse correlation with Ca2+-ATPase inhibition". New Journal of Chemistry 43 45 (2019): 17577-17587. https://doi.org/10.1039/C9NJ01208G.
    Publicado • 10.1039/C9NJ01208G
  21. Lagoa, Ricardo; Arias, Alejandro; Gutierrez-Merino, Carlos. Autor correspondente: Lagoa, Ricardo. "Correlation between the potency of flavonoids for cytochrome c reduction and inhibition of cardiolipin-induced peroxidase activity". BioFactors 43 3 (2017): 451-468. https://doi.org/10.1002%2Fbiof.1357.
    Publicado • 10.1002/biof.1357
  22. Arias, Alejandro; López-Sánchez, C.; Silva, Dorinda; Lagoa, Ricardo; Garcia-Lopez, V.; García-Martínez, V.; Gutierrez-Merino, Carlos. "High expression of cytochrome b 5 reductase isoform 3/cytochrome b 5 system in the cerebellum and pyramidal neurons of adult rat brain". Brain Structure and Function 221 4 (2016): 2147-2162. https://link.springer.com/article/10.1007/s00429-015-1036-5.
    Publicado • 10.1007/s00429-015-1036-5
  23. Liu, Feng; Lee, Dong-Hoon; Lagoa, Ricardo; Kumar, Sandeep. "New frontiers in biomedical science and engineering during 2014–2015 (Guest Editorial)". Bio-Medical Materials and Engineering 26 s1 (2015): 3-7. https://content.iospress.com/articles/bio-medical-materials-and-engineering/bme1283.
    Publicado • 10.3233/BME-151283
  24. Lagoa, Ricardo; Gañán, Carlos; López-Sánchez, Carmen; García-Martínez, Virginio; Gutierrez-Merino, Carlos. "The decrease of NAD(P)H:quinone oxidoreductase 1 activity and increase of ROS production by NADPH oxidases are early biomarkers in doxorubicin cardiotoxicity". Biomarkers 19 2 (2014): 142-153. http://hdl.handle.net/10400.8/2352.
    Publicado • 10.3109/1354750X.2014.885084
  25. Gutierrez-Merino, Carlos; Lopez-Sanchez, C.; Lagoa, Ricardo; Arias, Alejandro; Bueno, C.; Garcia-Martinez, V.. "Neuroprotective actions of flavonoids". Current Medicinal Chemistry 18 8 (2011): 1195-1212. https://doi.org/10.2174/092986711795029735.
    Publicado • 10.2174/092986711795029735
  26. Lagoa, Ricardo; Graziani, I.; Lopez-Sanchez, C.; Garcia-Martinez, V.; Gutierrez-Merino, Carlos. "Complex I and cytochrome c are molecular targets of flavonoids that inhibit hydrogen peroxide production by mitochondria". Biochimica et Biophysica Acta - Bioenergetics 1807 12 (2011): 1562-1572. https://doi.org/10.1016/j.bbabio.2011.09.022.
    Acesso aberto • Publicado • 10.1016/j.bbabio.2011.09.022
  27. Lagoa, Ricardo; Rodrigues, Joaquim. Autor correspondente: Lagoa, Ricardo. "Kinetic analysis of metal uptake by dry and gel alginate particles". Biochemical Engineering Journal 46 3 (2009): 320-326. http://dx.doi.org/10.1016/j.bej.2009.06.007.
    Publicado • 10.1016/j.bej.2009.06.007
  28. Lagoa, Ricardo; Lopez-Sanchez, C.; Arias, Alejandro; Gañan, C.M.; Garcia-Martinez, V.; Gutierrez-Merino, Carlos. "Kaempferol protects against rat striatal degeneration induced by 3-nitropropionic acid". Journal of Neurochemistry 111 2 (2009): 473-487. https://doi.org/10.1111/j.1471-4159.2009.06331.x.
    Acesso aberto • Publicado • 10.1111/j.1471-4159.2009.06331.x
  29. Silva, Rui M. P.; Manso, João P. H.; Rodrigues, Joaquim; Lagoa, Ricardo. Autor correspondente: Lagoa, Ricardo. "A comparative study of alginate beads and an ion-exchange resin for the removal of heavy metals from a metal plating effluent". Journal of Environmental Science and Health, Part A 43 11 (2008): 1311-1317. http://dx.doi.org/10.1080/10934520802177953.
    Publicado • 10.1080/10934520802177953
  30. Lagoa, Ricardo; Rodrigues, Joaquim. Autor correspondente: Lagoa, Ricardo. "Evaluation of Dry Protonated Calcium Alginate Beads for Biosorption Applications and Studies of Lead Uptake". Applied Biochemistry and Biotechnology 143 2 (2007): 115-128. http://dx.doi.org/10.1007/s12010-007-0041-4.
    Publicado • 10.1007/s12010-007-0041-4
  31. Rodrigues, Joaquim; Lagoa, Ricardo. Autor correspondente: Lagoa, Ricardo. "Copper ions binding in Cu-alginate gelation". Journal of Carbohydrate Chemistry 25 2-3 (2006): 219-232. https://doi.org/10.1080/07328300600732956.
    Publicado • 10.1080/07328300600732956
  32. Murtinho, D.; Lagoa, Ricardo; Garcia, F.A.P.; Gil, M.H.. "Cellulose derivatives membranes as supports for immobilisation of enzymes". Cellulose 5 4 (1998): 299-308. https://doi.org/10.1023/A:1009255126274.
    Publicado • 10.1023/A:1009255126274
Capítulo de livro
  1. Aureliano, Manuel; Dorinda, Marques-da-Silva; Serrano, Ana; Martins, João; Faleiro, Leonor; Fonseca, Custôdia; Fraqueza, Gil; Lagoa, Ricardo. "Polyoxometalates with Anticancer, Antibacterial and Antiviral Activities". In Polyoxometalates, 309-358. Jenny Stanford Publishing, 2022.
    Publicado • 10.1201/9781003277446-8
  2. Silva, João S.; Marques-da-Silva, Dorinda; Lagoa, Ricardo. Autor correspondente: Lagoa, Ricardo. "Towards the Development of Delivery Systems of Bioactive Compounds With Eyes Set on Pharmacokinetics". In Modeling and Control of Drug Delivery Systems, 125-144. Elsevier, 2021.
    Publicado • 10.1016/b978-0-12-821185-4.00006-3
  3. Marques-da-Silva, Dorinda; Rodrigues, Joaquim Rui; Lagoa, Ricardo. Autor correspondente: Lagoa, Ricardo. "Anthocyanins, effects in mitochondria and metabolism". In Mitochondrial Physiology and Vegetal Molecules, 267-300. Elsevier, 2021.
    Publicado • 10.1016/b978-0-12-821562-3.00028-9
  4. Lagoa, Ricardo; Gutierrez-Merino, Carlos. "Cytochrome c reducing agents and antiapoptotic action of antioxidants". In Cytochrome C: Roles and Therapeutic Implications, 1-49. New York, Estados Unidos: Nova Science Publishers, 2019.
    Publicado
  5. Silva, Dorinda; Francisco, R.; dos Reis Ferreira, V.; Forbat, L.; Lagoa, Ricardo; Videira, Paula Alexandra Quintela; Witters, P.; Jaeken, J.; Cassiman, D.. "An electronic questionnaire for liver assessment in congenital disorders of glycosylation (LeQCDG): A patient-centered study". 55-64. 2019.
    Publicado • 10.1007/8904_2018_121
  6. Lagoa, Ricardo; Murtinho, Dina; Gil, M.H.. "Membranes of Cellulose Derivatives as Supports for Immobilization of Enzymes (Chapter 15)". In ACS Symposium Series - Biopolymers (Utilizing Nature’s Advanced Materials), 228-234. Washington DC, Estados Unidos: American Chemical Society (Edited by S. Imam, R. Greene and B. Zaidi), 1999.
    Publicado • 10.1021/bk-1999-0723.ch015
Edição de número de revista
  1. Lagoa, Ricardo; Diniz, Mário. "Development of Protective Therapies Facing Toxic Environmental Exposures". Topic Issue associated to different Journals (2022): https://www.mdpi.com/topics/therapy_toxic.
    Publicado • Co-editor