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Identificação

Identificação pessoal

Nome completo
Arockia Jeyaprakash Arulanandam

Nomes de citação

  • Arulanandam, Arockia
  • A. Arockia Jeyaprakash
  • A. A. Jeyaprakash

Identificadores de autor

Ciência ID
5F16-3AD3-5A86
ORCID iD
0000-0002-1889-8635

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências Naturais - Ciências Biológicas - Biofísica
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2012/01/03 - Atual Investigador principal (carreira) (Investigação) The University of Edinburgh, Reino Unido
The University of Edinburgh, Reino Unido
(...)
Produções

Publicações

Artigo em revista
  1. Bethan Medina-Pritchard; Vasiliki Lazou; Juan Zou; Olwyn Byron; Maria A Abad; Juri Rappsilber; Patrick Heun; A Arockia Jeyaprakash. "Structural basis for centromere maintenance by Drosophila CENP -A chaperone CAL 1". The EMBO Journal (2020): https://doi.org/10.15252/embj.2019103234.
    10.15252/embj.2019103234
  2. Abad MA; Ruppert JG; Buzuk L; Wear M; Zou J; Webb KM; Kelly DA; et al. "Borealin-nucleosome interaction secures chromosome association of the chromosomal passenger complex.". The Journal of cell biology (2019): http://europepmc.org/abstract/med/31570499.
    10.1083/jcb.201905040
  3. Leontiou I; London N; May KM; Ma Y; Grzesiak L; Medina-Pritchard B; Amin P; et al. "The Bub1-TPR Domain Interacts Directly with Mad3 to Generate Robust Spindle Checkpoint Arrest.". Current biology : CB (2019): http://europepmc.org/abstract/med/31257143.
    10.1016/j.cub.2019.06.011
  4. Roure, V.; Medina-Pritchard, B.; Lazou, V.; Rago, L.; Anselm, E.; Venegas, D.; Jeyaprakash, A.A.; Heun, P.. "Reconstituting Drosophila Centromere Identity in Human Cells". Cell Reports 29 2 (2019): 464-479.e5. http://www.scopus.com/inward/record.url?eid=2-s2.0-85073123564&partnerID=MN8TOARS.
    10.1016/j.celrep.2019.08.067
  5. Marianne de la Roche; Claire Hamilton; Rebecca Mortensen; A. Arockia Jeyaprakash; Sanjay Ghosh; Paras K. Anand. "Trafficking of cholesterol to the ER is required for NLRP3 inflammasome activation". Journal of Cell Biology 217 10 (2018): 3560-3576. https://doi.org/10.1083/jcb.201709057.
    10.1083/jcb.201709057
  6. Anselm E; Thomae AW; Jeyaprakash AA; Heun P. "Oligomerization of Drosophila Nucleoplasmin-Like Protein is required for its centromere localization.". Nucleic acids research (2018): http://europepmc.org/abstract/med/30357352.
    10.1093/nar/gky988
  7. Jan G Ruppert; Kumiko Samejima; Melpomeni Platani; Oscar Molina; Hiroshi Kimura; A Arockia Jeyaprakash; Shinya Ohta; William C Earnshaw. "HP 1a targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry". The EMBO Journal 37 6 (2018): https://doi.org/10.15252/embj.201797677.
    10.15252/embj.201797677
  8. Welburn JPI; Jeyaprakash AA. "Mechanisms of Mitotic Kinase Regulation: A Structural Perspective.". Frontiers in cell and developmental biology (2018): http://europepmc.org/abstract/med/29459892.
    10.3389/fcell.2018.00006
  9. Novais-Cruz, M.; Abad, M.A.; van IJcken, W.F.J.; Galjart, N.; Jeyaprakash, A.A.; Maiato, H.; Ferrás, C.. "Mitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription". eLife 7 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85053869836&partnerID=MN8TOARS.
    10.7554/eLife.36898
  10. Frances Spiller; Bethan Medina-Pritchard; Maria Alba Abad; Martin A Wear; Oscar Molina; William C Earnshaw; A Arockia Jeyaprakash. "Molecular basis for Cdk1-regulated timing of Mis18 complex assembly and CENP-A deposition". EMBO reports 18 6 (2017): 894-905. https://doi.org/10.15252/embr.201643564.
    10.15252/embr.201643564
  11. Molina O; Vargiu G; Abad MA; Zhiteneva A; Jeyaprakash AA; Masumoto H; Kouprina N; Larionov V; Earnshaw WC. "Epigenetic engineering reveals a balance between histone modifications and transcription in kinetochore maintenance.". (2016): http://europepmc.org/abstract/med/27841270.
    10.1038/ncomms13334
  12. Capalbo L; Mela I; Abad MA; Jeyaprakash AA; Edwardson JM; D'Avino PP. "Coordinated regulation of the ESCRT-III component CHMP4C by the chromosomal passenger complex and centralspindlin during cytokinesis.". (2016): http://europepmc.org/abstract/med/27784789.
  13. Abad MA; Zou J; Medina-Pritchard B; Nigg EA; Rappsilber J; Santamaria A; Jeyaprakash AA. "Ska3 Ensures Timely Mitotic Progression by Interacting Directly With Microtubules and Ska1 Microtubule Binding Domain.". (2016): http://europepmc.org/abstract/med/27667719.
    10.1038/srep34042
  14. L. Subramanian; B. Medina-Pritchard; R. Barton; F. Spiller; R. Kulasegaran-Shylini; G. Radaviciute; R. C. Allshire; A. Arockia Jeyaprakash. "Centromere localization and function of Mis18 requires Yippee-like domain-mediated oligomerization". EMBO reports (2016): http://dx.doi.org/10.15252/embr.201541520.
    10.15252/embr.201541520
  15. Capalbo, L.; Mela, I.; Abad, M.A.; Jeyaprakash, A.A.; Edwardson, J.M.; D'Avino, P.P.. "Coordinated regulation of the ESCRT-III component CHMP4C by the chromosomal passenger complex and centralspindlin during cytokinesis". Open biology 6 10 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85020939682&partnerID=MN8TOARS.
    10.1098/rsob.160248
  16. Platani M; Trinkle-Mulcahy L; Porter M; Jeyaprakash AA; Earnshaw WC. "Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomes.". (2015): http://europepmc.org/abstract/med/26124292.
    10.1083/jcb.201410001
  17. Papini D; Langemeyer L; Abad MA; Kerr A; Samejima I; Eyers PA; Jeyaprakash AA; et al. "TD-60 links RalA GTPase function to the CPC in mitosis.". (2015): http://europepmc.org/abstract/med/26158537.
    10.1038/ncomms8678
  18. Abad MA; Medina B; Santamaria A; Zou J; Plasberg-Hill C; Madhumalar A; Jayachandran U; et al. "Structural basis for microtubule recognition by the human kinetochore Ska complex.". (2014): http://europepmc.org/abstract/med/24413531.
    10.1038/ncomms3964
  19. Alok Sharma; Gottfried Pohlentz; Kishore Babu Bobbili; A. Arockia Jeyaprakash; Thyageshwar Chandran; Michael Mormann; Musti J. Swamy; M. Vijayan. "The sequence and structure of snake gourd ( Trichosanthes anguina ) seed lectin, a three-chain nontoxic homologue of type II RIPs". Acta Crystallogr D Biol Cryst 69 8 (2013): 1493-1503. http://dx.doi.org/10.1107/s0907444913010020.
    10.1107/s0907444913010020
  20. Sharma, A.; Pohlentz, G.; Bobbili, K.B.; Jeyaprakash, A.A.; Chandran, T.; Mormann, M.; Swamy, M.J.; Vijayan, M.. "The sequence and structure of snake gourd (Trichosanthes anguina) seed lectin, a three-chain nontoxic homologue of type II RIPs". Acta Crystallographica Section D: Biological Crystallography 69 8 (2013): 1493-1503. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881286731&partnerID=MN8TOARS.
    10.1107/S0907444913010020
  21. A. Arockia Jeyaprakash; Anna Santamaria; Uma Jayachandran; Ying Wai Chan; Christian Benda; Erich A. Nigg; Elena Conti. "Structural and Functional Organization of the Ska Complex, a Key Component of the Kinetochore-Microtubule Interface". Molecular Cell 46 3 (2012): 274-286. http://dx.doi.org/10.1016/j.molcel.2012.03.005.
    10.1016/j.molcel.2012.03.005
  22. Chan YW; Jeyaprakash AA; Nigg EA; Santamaria A. "Aurora B controls kinetochore-microtubule attachments by inhibiting Ska complex-KMN network interaction.". (2012): http://europepmc.org/abstract/med/22371557.
    10.1083/jcb.201109001
  23. A. Arockia Jeyaprakash; Claire Basquin; Uma Jayachandran; Elena Conti. "Structural Basis for the Recognition of Phosphorylated Histone H3 by the Survivin Subunit of the Chromosomal Passenger Complex". Structure 19 11 (2011): 1625-1634. http://dx.doi.org/10.1016/j.str.2011.09.002.
    10.1016/j.str.2011.09.002
  24. Thomas N Gaitanos; Anna Santamaria; A Arockia Jeyaprakash; Bin Wang; Elena Conti; Erich A Nigg. "Stable kinetochore–microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3". EMBO J 28 10 (2009): 1442-1452. http://dx.doi.org/10.1038/emboj.2009.96.
    10.1038/emboj.2009.96
  25. A. Arockia Jeyaprakash; Ulf R. Klein; Doris Lindner; Judith Ebert; Erich A. Nigg; Elena Conti. "Structure of a Survivin–Borealin–INCENP Core Complex Reveals How Chromosomal Passengers Travel Together". Cell 131 2 (2007): 271-285. http://dx.doi.org/10.1016/j.cell.2007.07.045.
    10.1016/j.cell.2007.07.045
  26. A. Arockia Jeyaprakash; G. Jayashree; S.K. Mahanta; C.P. Swaminathan; K. Sekar; A. Surolia; M. Vijayan. "Structural Basis for the Energetics of Jacalin–Sugar Interactions: Promiscuity Versus Specificity". Journal of Molecular Biology 347 1 (2005): 181-188. http://dx.doi.org/10.1016/j.jmb.2005.01.015.
    10.1016/j.jmb.2005.01.015
  27. A.Arockia Jeyaprakash; Anand Srivastav; A Surolia; M Vijayan. "Structural Basis for the Carbohydrate Specificities of Artocarpin: Variation in the Length of a Loop as a Strategy for Generating Ligand Specificity". Journal of Molecular Biology 338 4 (2004): 757-770. http://dx.doi.org/10.1016/j.jmb.2004.03.040.
    10.1016/j.jmb.2004.03.040
  28. S. Kundhavai Natchiar; A. Arockia Jeyaprakash; T. N. C. Ramya; C. J. Thomas; K. Suguna; A. Surolia; M. Vijayan. "Structural plasticity of peanut lectin: an X-ray analysis involving variation in pH, ligand binding and crystal structure". Acta Crystallogr D Biol Cryst 60 2 (2004): 211-219. http://dx.doi.org/10.1107/s090744490302849x.
    10.1107/s090744490302849x
  29. Kundhavai Natchiar, S.; Arockia Jeyaprakash, A.; Ramya, T.N.C.; Thomas, C.J.; Suguna, K.; Surolia, A.; Vijayan, M.. "Structural plasticity of peanut lectin: An X-ray analysis involving variation in pH, ligand binding and crystal structure". Acta Crystallographica Section D: Biological Crystallography 60 2 (2004): 211-219. http://www.scopus.com/inward/record.url?eid=2-s2.0-4644296063&partnerID=MN8TOARS.
    10.1107/S090744490302849X
  30. K Sekar; S Vaijayanthi Mala; M Yogavel; D Velmurugan; Ming-Jye Poi; B.S Vishwanath; T.V Gowda; A Arokia Jeyaprakash; M.-D Tsai. "Crystal Structures of the Free and Anisic Acid Bound Triple Mutant of Phospholipase A2". Journal of Molecular Biology 333 2 (2003): 367-376. http://dx.doi.org/10.1016/j.jmb.2003.08.032.
    10.1016/j.jmb.2003.08.032
  31. A Arockia Jeyaprakash; S Katiyar; C.P Swaminathan; K Sekar; A Surolia; M Vijayan. "Structural Basis of the Carbohydrate Specificities of Jacalin: An X-ray and Modeling Study". Journal of Molecular Biology 332 1 (2003): 217-228. http://dx.doi.org/10.1016/s0022-2836(03)00901-x.
    10.1016/s0022-2836(03)00901-x
  32. Jeyaprakash, A.A.; Katiyar, S.; Swaminathan, C.P.; Sekar, K.; Surolia, A.; Vijayan, M.. "Structural basis of the carbohydrate specificities of jacalin: An X-ray and modeling study". Journal of Molecular Biology 332 1 (2003): 217-228. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042511948&partnerID=MN8TOARS.
    10.1016/S0022-2836(03)00901-X
  33. A.Arockia Jeyaprakash; P. Geetha Rani; G. Banuprakash Reddy; S. Banumathi; C. Betzel; K. Sekar; A. Surolia; M. Vijayan. "Crystal Structure of the Jacalin–T-antigen Complex and a Comparative Study of Lectin–T-antigen Complexes". Journal of Molecular Biology 321 4 (2002): 637-645. http://dx.doi.org/10.1016/s0022-2836(02)00674-5.
    10.1016/s0022-2836(02)00674-5
  34. J.V Pratap; A.Arockia Jeyaprakash; P.Geetha Rani; K Sekar; A Surolia; M Vijayan. "Crystal structures of artocarpin, a Moraceae lectin with mannose specificity, and its complex with methyl-a-d-mannose: implications to the generation of carbohydrate specificity". Journal of Molecular Biology 317 2 (2002): 237-247. http://dx.doi.org/10.1006/jmbi.2001.5432.
    10.1006/jmbi.2001.5432
  35. Rajakannan, V.; Yogavel, M.; Poi, M.-J.; Jeyaprakash, A.A.; Jeyakanthan, J.; Velmurugan, D.; Tsai, M.-D.; Sekar, K.. "Observation of additional calcium ion in the crystal structure of the triple mutant K56,120,121M of bovine pancreatic phospholipase A2". Journal of Molecular Biology 324 4 (2002): 755-762. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036922194&partnerID=MN8TOARS.
    10.1016/S0022-2836(02)01132-4
  36. Jeyaprakash, A.A.; Rani, P.G.; Reddy, G.B.; Banumathi, S.; Betzel, C.; Sekar, K.; Surolia, A.; Vijayan, M.. "Crystal structure of the jacalin-T-antigen complex and a comparative study of lectin-T-antigen complexes". Journal of Molecular Biology 321 4 (2002): 637-645. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036971194&partnerID=MN8TOARS.
    10.1016/S0022-2836(02)00674-5
  37. V. Rajakannan; M. Yogavel; Ming-Jye Poi; A.Arockia Jeyaprakash; J. Jeyakanthan; D. Velmurugan; Ming-Daw Tsai; K. Sekar. "Observation of Additional Calcium Ion in the Crystal Structure of the Triple Mutant K56,120,121M of Bovine Pancreatic Phospholipase A2". Journal of Molecular Biology 324 4 (2002): 755-762. http://dx.doi.org/10.1016/s0022-2836(02)01132-4.
    10.1016/s0022-2836(02)01132-4
  38. P. Adhikari; K. Bachhawat-Sikder; C. J. Thomas; R. Ravishankar; A. A. Jeyaprakash; V. Sharma; M. Vijayan; A. Surolia. "Mutational Analysis at Asn-41 in Peanut Agglutinin: A RESIDUE CRITICAL FOR THE BINDING OF THE TUMOR-ASSOCIATED THOMSEN-FRIEDENREICH ANTIGEN". Journal of Biological Chemistry 276 44 (2001): 40734-40739. http://dx.doi.org/10.1074/jbc.m103040200.
    10.1074/jbc.m103040200
  39. N. Manoj; A. Arockia Jeyaprakash; J. V. Pratap; Sneha Sudha Komath; Roopa Kenoth; Musti. J. Swamy; M. Vijayan. "Crystallization and preliminary X-ray studies of snake gourd lectin: homology with type II ribosome-inactivating proteins". Acta Crystallogr D Biol Cryst 57 6 (2001): 912-914. http://dx.doi.org/10.1107/s0907444901004620.
    10.1107/s0907444901004620
  40. Adhikari, P.; Bachhawat-Sikder, K.; Thomas, C.J.; Ravishankar, R.; Jeyaprakash, A.A.; Sharma, V.; Vijayan, M.; Surolia, A.. "Mutational analysis at Asn-41 in peanut agglutinin. A residue critical for the binding of the tumor-associated Thomsen-Friedenreich antigen". Journal of Biological Chemistry 276 44 (2001): 40734-40739. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035798598&partnerID=MN8TOARS.
    10.1074/jbc.M103040200
  41. Manoj, N.; Jeyaprakash, A.A.; Pratap, J.V.; Komath, S.S.; Kenoth, R.; Swamy, M.J.; Vijayan, M.. "Crystallization and preliminary X-ray studies of snake gourd lectin: Homology with type II ribosome-inactivating proteins". Acta Crystallographica Section D: Biological Crystallography 57 6 (2001): 912-914. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034988534&partnerID=MN8TOARS.
    10.1107/S0907444901004620
Capítulo de livro
  1. Capalbo, L.; Mela, I.; Abad, M.A.; Jeyaprakash, A.A.; Edwardson, J.M.; D’Avino, P.P.. "Purification of Recombinant ESCRT-III Proteins and Their Use in Atomic Force Microscopy and In Vitro Binding and Phosphorylation Assays". 203-217. 2019.
    10.1007/978-1-4939-9492-2_15

Outros

Outra produção
  1. Analysis of Complex DNA Rearrangements During Early Stages of HAC Formation. 2020. Elisa Pesenti; Mikhail Liskovykh; Koei Okazaki; Alessio Mallozzi; Caitlin Reid; Maria Alba Abad; A. Arockia Jeyaprakash; et al. https://doi.org/10.1101/2020.07.02.184408.
    10.1101/2020.07.02.184408
  2. SUMOylation targets shugoshin to stabilize sister kinetochore biorientation. 2019. Xue Bessie Su; Menglu Wang; Claudia Schaffner; Dean Clift; Olga O. Nerusheva; Triin Tammasalu; Andreas Wallek; et al. https://doi.org/10.1101/840157.
    10.1101/840157
  3. Coordination of NDC80 and Ska complexes at the kinetochore-microtubule interface in human cells. 2019. Robert Wimbish; Keith F. DeLuca; Jeanne E. Mick; Jack Himes; Ignacio J. Sánchez; A. Arockia Jeyaprakash; Jennifer G. DeLuca. https://doi.org/10.1101/820530.
    10.1101/820530
  4. Direct Nucleosome Binding of Borealin Secures Chromosome Association and Function of the Chromosomal Passenger complex. 2019. A. Arockia Jeyaprakash. http://dx.doi.org/10.1101/620385.
    10.1101/620385
  5. Epigenetic inheritance of centromere identity in a heterologous system. 2019. A. Arockia Jeyaprakash. http://dx.doi.org/10.1101/560391.
    10.1101/560391
  6. Mitotic progression, arrest, exit or death is determined by centromere integrity and independent of de novo transcription. 2018. Marco Novais-Cruz; Maria Alba Abad; Wilfred F.J. van Ijcken; Niels Galjart; A. Arockia Jeyaprakash; Helder Maiato; Cristina Ferrás. https://doi.org/10.1101/287151.
    10.1101/287151