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Identificação

Identificação pessoal

Nome completo
Jennifer Scott

Nomes de citação

  • Scott, Jennifer

Identificadores de autor

Ciência ID
611A-F11D-380F
ORCID iD
0000-0002-6401-962X

Endereços de correio eletrónico

  • jenni-scott@outlook.com (Profissional)

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês (Idioma materno)
Formação
Grau Classificação
2017/09 - 2023/07/14
Concluído
 PhD Molecular Biology (Doctor of Philosophy)
The University of Manchester, Reino Unido
"Methionine Synthases as Targets for Antifungal Drug Development" (TESE/DISSERTAÇÃO)
2010/10 - 2014/06
Concluído
 Biology with Professional Placement (Bachelor)
University of Bath, Reino Unido
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2012/08 - 2013/09 Assistente de Investigação (carreira) (Investigação) The University of Iowa, Estados Unidos

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/02 - 2024/01 Part-Time Graduate Teaching Assistant The University of Manchester, Reino Unido
2016/05 - 2017/09 Reserch Technician The University of Manchester, Reino Unido
2016 - 2016/04 Freelance Medical Writer/Account Executive Cancer Intelligence Ltd, Reino Unido
2013/10 - 2013/12 Final Year Project Student University of Bath, Reino Unido
Produções

Publicações

Artigo em revista
  1. Reem Alharthi; Monica Sueiro-Olivares; Isabelle Storer; Hajer Bin Shuraym; Jennifer Scott; Reem Al-Shidhani; Rachael Fortune-Grant; et al. "The sulfur-related metabolic status of Aspergillus fumigatus during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target". Virulence (2025): http://dx.doi.org/10.1080/21505594.2024.2449075.
    10.1080/21505594.2024.2449075
  2. Scott, Jennifer; Amich, Jorge. "The role of methionine synthases in fungal metabolism and virulence". Essays in Biochemistry 67 5 (2023): 853-863. http://dx.doi.org/10.1042/ebc20230007.
    Publicado • 10.1042/ebc20230007
  3. Jennifer Scott; Clara Valero; Álvaro Mato-López; Ian J. Donaldson; Alejandra Roldán; Harry Chown; Norman Van Rhijn; et al. "Aspergillus fumigatus Can Display Persistence to the Fungicidal Drug Voriconazole". Microbiology Spectrum (2023): https://doi.org/10.1128/spectrum.04770-22.
    10.1128/spectrum.04770-22
  4. "Point Mutation or Overexpression of Aspergillus fumigatus cyp51B, Encoding Lanosterol 14a-Sterol Demethylase, Leads to Triazole Resistance". Antimicrobial Agents and Chemotherapy 65 10 (2021): http://dx.doi.org/10.1128/aac.01252-21.
    10.1128/aac.01252-21
  5. "Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response". PLOS Biology 19 6 (2021): e3001247-e3001247. http://dx.doi.org/10.1371/journal.pbio.3001247.
    10.1371/journal.pbio.3001247
  6. Jennifer Scott; Monica Sueiro-Olivares; Benjamin P. Thornton; Rebecca A. Owens; Howbeer Muhamadali; Rachael Fortune-Grant; Darren Thomson; et al. "Targeting Methionine Synthase in a Fungal Pathogen Causes a Metabolic Imbalance That Impacts Cell Energetics, Growth, and Virulence". mBio 11 5 (2020): https://doi.org/10.1128/mBio.01985-20.
    10.1128/mBio.01985-20
  7. "Pseudomonas aeruginosa-Derived Volatile Sulfur Compounds Promote Distal Aspergillus fumigatus Growth and a Synergistic Pathogen-Pathogen Interaction That Increases Pathogenicity in Co-infection". Frontiers in Microbiology (2019): http://dx.doi.org/10.3389/fmicb.2019.02311.
    10.3389/fmicb.2019.02311
Pré-impressão
  1. Reem Alharthi; Monica Sueiro-Olivares; Isabelle Storer; Hajer Alshammri; Jennifer Scott; Reem Al-Shidhani; Rachael Fortune-Grant; et al. "The sulfur-related metabolic status ofAspergillus fumigatusduring infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target". 2024. https://doi.org/10.1101/2024.03.08.582945.
    10.1101/2024.03.08.582945

Outros

Outra produção
  1. Primary Metabolism of Human Pathogenic Fungi, Importance for Virulence and Potential for Drug Development. 2021. Jennifer Scott; Jorge Amich. https://doi.org/10.1016%2Fb978-0-12-818731-9.00059-8.
    10.1016/b978-0-12-818731-9.00059-8
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2022/03 Methionine synthase as a target for antifungal drug development 31st Fungal Genetics Conference
Genetics Society of America (Asilomar, Estados Unidos)
2019/05 The role of volatile sulphur compounds in Pseudomonas aeruginosa-Aspergillus fumigatus co-infection FEBS Advanced Lecture Course on Human Fungal Pathogens
Federation of European Biochemical Societies (Nice, França)
2019/03 Methionine synthases as targets for antifungal drug development 55th British Society for Medical Mycology Annual Meeting
British Society for Medical Mycology (Birmingham, Reino Unido)
Distinções

Prémio

2022 University of Manchester Doctoral Academy Conference Support Grant Award
The University of Manchester, Reino Unido
2022 Fungal Genetics Conference Travel Award
Genetics Society of America, Estados Unidos
2019 FEBS Youth Travel Fund Grant
Federation of European Biochemical Societies, Reino Unido
2018 BSAC Best Poster Award
The British Society for Antimicrobial Chemotherapy, Reino Unido
2018 Zochonis Special Enterprise Award
The University of Manchester, Reino Unido
2017 The British Society for Antimicrobial Chemotherapy PhD Studentship
The British Society for Antimicrobial Chemotherapy, Reino Unido
2017 8th Advances Against Aspergillosis Scholarship Award
European Confederation of Medical Mycology, Suiça