???global.info.a_carregar???
Identificação

Identificação pessoal

Nome completo
Stefan Poehlmann

Nomes de citação

  • Poehlmann, Stefan

Identificadores de autor

Ciência ID
6914-F6D9-A92B
ORCID iD
0000-0001-6086-9136
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2010/11 - Atual Investigador principal (carreira) (Investigação) Deutsches Primatenzentrum GmbH - Leibniz-Institut für Primatenforschung, Alemanha
Produções

Publicações

Artigo em revista
  1. Prerna Arora; Amy Kempf; Inga Nehlmeier; Luise Graichen; Martin S. Winkler; Martin Lier; Sebastian Schulz; et al. "No evidence for increased cell entry or antibody evasion by Delta sublineage AY.4.2". Cellular & Molecular Immunology (2022): https://doi.org/10.1038/s41423-021-00811-8.
    10.1038/s41423-021-00811-8
  2. Abdul Rahman Siregar; Sabine Gärtner; Jasper Götting; Philipp Stegen; Artur Kaul; Thomas Schulz; Stefan Pöhlmann; Michael Winkler. "A Recombinant System and Reporter Viruses for Papiine Alphaherpesvirus 2". Viruses (2022): https://www.mdpi.com/1999-4915/14/1/91.
    10.3390/v14010091
  3. Markus Hoffmann; Stefan Pöhlmann. "Novel SARS-CoV-2 receptors: ASGR1 and KREMEN1". Cell Research (2022): https://doi.org/10.1038/s41422-021-00603-9.
    10.1038/s41422-021-00603-9
  4. Prerna Arora; Stefan Pöhlmann; Markus Hoffmann. "Mutation D614G increases SARS-CoV-2 transmission". Signal Transduction and Targeted Therapy 6 1 (2021): https://doi.org/10.1038/s41392-021-00502-w.
    10.1038/s41392-021-00502-w
  5. Swantje I. Hammerschmidt; Berislav Bosnjak; Günter Bernhardt; Michaela Friedrichsen; Inga Ravens; Alexandra Dopfer-Jablonka; Markus Hoffmann; et al. "Neutralization of the SARS-CoV-2 Delta variant after heterologous and homologous BNT162b2 or ChAdOx1 nCoV-19 vaccination". Cellular & Molecular Immunology (2021): https://doi.org/10.1038/s41423-021-00755-z.
    10.1038/s41423-021-00755-z
  6. Nadine Krüger; Cheila Rocha; Sandra Runft; Johannes Krüger; Iris Färber; Federico Armando; Eva Leitzen; et al. "The Upper Respiratory Tract of Felids Is Highly Susceptible to SARS-CoV-2 Infection". International Journal of Molecular Sciences 22 19 (2021): 10636-10636. https://doi.org/10.3390/ijms221910636.
    10.3390/ijms221910636
  7. "Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5.". Nature communications (2021): https://europepmc.org/articles/PMC8423819.
    10.1038/s41467-021-25519-1
  8. "SARS-CoV-2 delta variant neutralisation after heterologous ChAdOx1-S/BNT162b2 vaccination.". Lancet (London, England) (2021): https://europepmc.org/articles/PMC8372487.
    10.1016/s0140-6736(21)01891-2
  9. "A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model.". European journal of immunology (2021): https://europepmc.org/articles/PMC8420377.
    10.1002/eji.202149374
  10. "SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants.". PLoS medicine (2021): https://europepmc.org/articles/PMC8291755.
    10.1371/journal.pmed.1003656
  11. Markus Hoffmann; Stefan Pöhlmann. "How SARS-CoV-2 makes the cut". Nature Microbiology (2021): https://doi.org/10.1038/s41564-021-00931-x.
    10.1038/s41564-021-00931-x
  12. "Urinary Levels of SARS-CoV-2 Nucleocapsid Protein Associate With Risk of AKI and COVID-19 Severity: A Single-Center Observational Study.". Frontiers in medicine (2021): https://europepmc.org/articles/PMC8185060.
    10.3389/fmed.2021.644715
  13. "Therapeutic Application of alpha-1-antitrypsin in COVID-19.". American journal of respiratory and critical care medicine (2021): https://doi.org/10.1164/rccm.202104-0833LE.
    10.1164/rccm.202104-0833le
  14. "Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles.". BMC biology (2021): https://europepmc.org/articles/PMC8091782.
    10.1186/s12915-021-01020-5
  15. "The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways.". PLoS pathogens (2021): https://europepmc.org/articles/PMC8061995.
    10.1371/journal.ppat.1009500
  16. "SARS-CoV-2 mutations acquired in mink reduce antibody-mediated neutralization.". Cell reports (2021): https://doi.org/10.1016/j.celrep.2021.109017.
    10.1016/j.celrep.2021.109017
  17. Gergely Imre; Verena Krähling; Madeleine Eichler; Sandra Trautmann; Nerea Ferreirós; M. Javad Aman; Fatah Kashanchi; et al. "The sphingosine kinase 1 activator, K6PC-5, attenuates Ebola virus infection". iScience 24 4 (2021): 102266-102266. https://doi.org/10.1016/j.isci.2021.102266.
    10.1016/j.isci.2021.102266
  18. Markus Hoffmann; Yeonhwa Jin; Stefan Pöhlmann. "Dalbavancin: novel candidate for COVID-19 treatment". Cell Research (2021): https://doi.org/10.1038/s41422-020-00459-5.
    10.1038/s41422-020-00459-5
  19. "SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies.". Cell (2021): https://europepmc.org/articles/PMC7980144.
    10.1016/j.cell.2021.03.036
  20. "Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection.". Nature communications (2021): https://europepmc.org/articles/PMC7979852.
    10.1038/s41467-021-21972-0
  21. "Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity.". EBioMedicine (2021): https://europepmc.org/articles/PMC7930809.
    10.1016/j.ebiom.2021.103255
  22. Katrin Anne Becker; Alexander Carpinteiro; Markus Hoffmann; Stefan Pöhlmann; Johannes Kornhuber; Erich Gulbins. "Ex vivo assay to evaluate the efficacy of drugs targeting sphingolipids in preventing SARS-CoV-2 infection of nasal epithelial cells". STAR Protocols 2 1 (2021): 100356-100356. https://doi.org/10.1016/j.xpro.2021.100356.
    10.1016/j.xpro.2021.100356
  23. "Natural cystatin C fragments inhibit GPR15-mediated HIV and SIV infection without interfering with GPR15L signaling.". Proceedings of the National Academy of Sciences of the United States of America (2021): https://europepmc.org/articles/PMC7826402.
    10.1073/pnas.2023776118
  24. Alexander Carpinteiro; Barbara Gripp; Markus Hoffmann; Stefan Pöhlmann; Nicolas Hoertel; Michael J. Edwards; Markus Kamler; et al. "Inhibition of acid sphingomyelinase by ambroxol prevents SARS-CoV-2 entry into epithelial cells". Journal of Biological Chemistry 296 (2021): 100701-100701. https://doi.org/10.1016/j.jbc.2021.100701.
    10.1016/j.jbc.2021.100701
  25. Tim Hempel; Lluís Raich; Simon Olsson; Nurit P. Azouz; Andrea M. Klingler; Markus Hoffmann; Stefan Pöhlmann; Marc E. Rothenberg; Frank Noé. "Molecular mechanism of inhibiting the SARS-CoV-2 cell entry facilitator TMPRSS2 with camostat and nafamostat". Chemical Science (2021): https://doi.org/10.1039/D0SC05064D.
    10.1039/D0SC05064D
  26. Ruth Lydia Olga Lambertz; Ingo Gerhauser; Inga Nehlmeier; Sabine Gärtner; Michael Winkler; Sarah Rebecca Leist; Heike Kollmus; Stefan Pöhlmann; Klaus Schughart. "H2 influenza A virus is not pathogenic in Tmprss2 knock-out mice". Virology Journal (2020): https://doi.org/10.1186/s12985-020-01323-z.
    10.1186/s12985-020-01323-z
  27. "Camostat Mesylate May Reduce Severity of Coronavirus Disease 2019 Sepsis: A First Observation.". Critical care explorations (2020): https://europepmc.org/articles/PMC7671878.
    10.1097/cce.0000000000000284
  28. "Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods.". Cellular & molecular immunology (2020): https://europepmc.org/articles/PMC7604543.
    10.1038/s41423-020-00573-9
  29. "Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells.". Cell reports. Medicine (2020): https://europepmc.org/articles/PMC7598530.
    10.1016/j.xcrm.2020.100142
  30. "Glycan-Gold Nanoparticles as Multifunctional Probes for Multivalent Lectin-Carbohydrate Binding: Implications for Blocking Virus Infection and Nanoparticle Assembly.". Journal of the American Chemical Society (2020): https://doi.org/10.1021/jacs.0c06793.
    10.1021/jacs.0c06793
  31. Markus Hoffmann; Kirstin Mösbauer; Heike Hofmann-Winkler; Artur Kaul; Hannah Kleine-Weber; Nadine Krüger; Nils C. Gassen; et al. "Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2". Nature 585 7826 (2020): 588-590. https://doi.org/10.1038/s41586-020-2575-3.
    10.1038/s41586-020-2575-3
  32. "LY6E impairs coronavirus fusion and confers immune control of viral disease.". Nature microbiology (2020): https://europepmc.org/articles/PMC7916999.
    10.1038/s41564-020-0769-y
  33. Markus Hoffmann; Simon Schroeder; Hannah Kleine-Weber; Marcel A. Müller; Christian Drosten; Stefan Pöhlmann. "Nafamostat Mesylate Blocks Activation of SARS-CoV-2: New Treatment Option for COVID-19". Antimicrobial Agents and Chemotherapy 64 6 (2020): https://doi.org/10.1128/AAC.00754-20.
    10.1128/AAC.00754-20
  34. "Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.". Cell (2020): https://europepmc.org/articles/PMC7199733.
    10.1016/j.cell.2020.04.031
  35. "A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells.". Molecular cell (2020): https://europepmc.org/articles/PMC7194065.
    10.1016/j.molcel.2020.04.022
  36. "SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.". Cell (2020): https://europepmc.org/articles/PMC7102627.
    10.1016/j.cell.2020.02.052
  37. Hannah Kleine-Weber; Simon Schroeder; Nadine Krüger; Alexander Prokscha; Hassan Y. Naim; Marcel A. Müller; Christian Drosten; Stefan Pöhlmann; Markus Hoffmann. "Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus". Emerging Microbes & Infections (2020): https://doi.org/10.1080/22221751.2020.1713705.
    10.1080/22221751.2020.1713705
  38. Ekaterina Chukhno; Sabine Gärtner; Abdul Rahman Siregar; Alexander Mehr; Marie Wende; Stoyan Petkov; Jasper Götting; et al. "A Fosmid-Based System for the Generation of Recombinant Cercopithecine Alphaherpesvirus 2 Encoding Reporter Genes". Viruses (2019): https://doi.org/10.3390/v11111026.
    10.3390/v11111026
  39. Michael Winkler; Zandrea Ambrose; Sabine Gärtner; Lara Markus; Markus Hoffmann; Inga Nehlmeier; Michael Krawczak; Ulrike Sauermann; Stefan Pöhlmann. "Role of rhesus macaque IFITM3(2) in simian immunodeficiency virus infection of macaques". PLOS ONE (2019): https://doi.org/10.1371/journal.pone.0224082.
    10.1371/journal.pone.0224082
  40. Markus Hoffmann; Svenja Victoria Kaufmann; Carina Fischer; Wiebke Maurer; Anna-Sophie Moldenhauer; Stefan Pöhlmann. "Analysis of Resistance of Ebola Virus Glycoprotein-Driven Entry Against MDL28170, An Inhibitor of Cysteine Cathepsins". Pathogens (2019): https://doi.org/10.3390/pathogens8040192.
    10.3390/pathogens8040192
  41. Manon Laporte; Annelies Stevaert; Valerie Raeymaekers; Talitha Boogaerts; Inga Nehlmeier; Winston Chiu; Mohammed Benkheil; et al. "Hemagglutinin Cleavability, Acid Stability, and Temperature Dependence Optimize Influenza B Virus for Replication in Human Airways". Journal of Virology (2019): https://doi.org/10.1128/JVI.01430-19.
    10.1128/JVI.01430-19
  42. Michael Winkler; Florian Wrensch; Pascale Bosch; Maike Knoth; Michael Schindler; Sabine Gärtner; Stefan Pöhlmann. "Analysis of IFITM-IFITM Interactions by a Flow Cytometry-Based FRET Assay". International Journal of Molecular Sciences 20 16 (2019): 3859-3859. https://doi.org/10.3390/ijms20163859.
    10.3390/ijms20163859
  43. Dhingra A; Ganzenmueller T; Hage E; Suárez NM; Mätz-Rensing K; Widmer D; Pöhlmann S; et al. "Novel Virus Related to Kaposi's Sarcoma-Associated Herpesvirus from Colobus Monkey.". Emerging infectious diseases (2019): http://europepmc.org/abstract/med/31310220.
    10.3201/eid2508.181802
  44. Grewer A; Bleyer M; Mätz-Rensing K; Hahn AS; Rüggeberg T; Babaryka G; Zimmermann A; Pöhlmann S; Kaul A. "Kaposi Sarcoma in Mantled Guereza.". Emerging infectious diseases (2019): http://europepmc.org/abstract/med/31310216.
    10.3201/eid2508.181804
  45. Ruth L. O. Lambertz; Ingo Gerhauser; Inga Nehlmeier; Sarah R. Leist; Heike Kollmus; Stefan Pöhlmann; Klaus Schughart. "Tmprss2 knock-out mice are resistant to H10 influenza A virus pathogenesis". Journal of General Virology 100 7 (2019): 1073-1078. https://doi.org/10.1099/jgv.0.001274.
    10.1099/jgv.0.001274
  46. Korniy N; Goyal A; Hoffmann M; Samatova E; Peske F; Pöhlmann S; Rodnina MV. "Modulation of HIV-1 Gag/Gag-Pol frameshifting by tRNA abundance.". Nucleic acids research (2019): http://europepmc.org/abstract/med/30968122.
    10.1093/nar/gkz202
  47. Wrensch F; Ligat G; Heydmann L; Schuster C; Zeisel MB; Pessaux P; Habersetzer F; et al. "Interferon-Induced Transmembrane Proteins Mediate Viral Evasion in Acute and Chronic Hepatitis C Virus Infection.". Hepatology (Baltimore, Md.) (2019): http://europepmc.org/abstract/med/31062385.
    10.1002/hep.30699
  48. Braun E; Hotter D; Koepke L; Zech F; Groß R; Sparrer KMJ; Müller JA; et al. "Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins.". Cell reports (2019): http://europepmc.org/abstract/med/31091448.
    10.1016/j.celrep.2019.04.063
  49. Teresa Plegge; Jens H. Kuhn; Martin Spiegel; Nadine Krüger; Inga Nehlmeier; Michael Winkler; Mariana González Hernández; Stefan Pöhlmann. "Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of endosomal cathepsins". PLOS ONE (2019): https://doi.org/10.1371/journal.pone.0214968.
    10.1371/journal.pone.0214968
  50. González-Hernández M; Müller A; Hoenen T; Hoffmann M; Pöhlmann S. "Calu-3¿cells are largely resistant to entry driven by filovirus glycoproteins and the entry defect can be rescued by directed expression of DC-SIGN or cathepsin L.". Virology (2019): http://europepmc.org/abstract/med/30999160.
    10.1016/j.virol.2019.03.020
  51. Artur Kaul; Uwe Schönmann; Stefan Pöhlmann. "Seroprevalence of viral infections in captive rhesus and cynomolgus macaques". Primate Biology (2019): https://doi.org/10.5194/pb-6-1-2019.
    10.5194/pb-6-1-2019
  52. Najat Bdeir; Balaji Manicassamy; Prerna Arora; Sabine Gärtner; Markus Hoffmann; Udo Reichl; Stefan Pöhlmann; Michael Winkler. "A system for production of defective interfering particles in the absence of infectious influenza A virus". PLOS ONE (2019): https://doi.org/10.1371/journal.pone.0212757.
    10.1371/journal.pone.0212757
  53. Francisco J. Zapatero-Belinchón; Erik Dietzel; Olga Dolnik; Katinka Döhner; Rui Costa; Barbara Hertel; Barbora Veselkova; et al. "Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors". Viruses (2019): https://www.mdpi.com/1999-4915/11/3/275.
    10.3390/v11030275
  54. Nehls J; Businger R; Hoffmann M; Brinkmann C; Fehrenbacher B; Schaller M; Maurer B; et al. "Release of Immunomodulatory Ebola Virus Glycoprotein-Containing Microvesicles Is Suppressed by Tetherin in a Species-Specific Manner.". Cell reports (2019): http://europepmc.org/abstract/med/30759394.
    10.1016/j.celrep.2019.01.065
  55. Markus Hoffmann; Enrika Schütze; Andreas Bernhard; Lennart Schlaphoff; Artur Kaul; Sandra Schöniger; Stefan Pöhlmann. "Disease Manifestation and Viral Sequences in a Bonobo More Than 30 Years after Papillomavirus Infection". Pathogens 8 1 (2019): 13-13. https://doi.org/10.3390/pathogens8010013.
    10.3390/pathogens8010013
  56. Hannah Kleine-Weber; Mahmoud Tarek Elzayat; Lingshu Wang; Barney S. Graham; Marcel A. Müller; Christian Drosten; Stefan Pöhlmann; Markus Hoffmann; Tom Gallagher. "Mutations in the Spike Protein of Middle East Respiratory Syndrome Coronavirus Transmitted in Korea Increase Resistance to Antibody-Mediated Neutralization". Journal of Virology 93 2 (2019): https://doi.org/10.1128/JVI.01381-18.
    10.1128/JVI.01381-18
  57. Hoffmann M; Nehlmeier I; Brinkmann C; Krähling V; Behner L; Moldenhauer AS; Krüger N; et al. "Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells.". Journal of virology (2019): http://europepmc.org/abstract/med/30429347.
    10.1128/jvi.01821-18
  58. Hannah Kleine-Weber; Mahmoud Tarek Elzayat; Markus Hoffmann; Stefan Pöhlmann. "Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein". Scientific Reports 8 1 (2018): https://doi.org/10.1038/s41598-018-34859-w.
    10.1038/s41598-018-34859-w
  59. Pawel Zmora; Markus Hoffmann; Heike Kollmus; Anna-Sophie Moldenhauer; Olga Danov; Armin Braun; Michael Winkler; Klaus Schughart; Stefan Pöhlmann. "TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1". Journal of Biological Chemistry (2018): jbc.RA118.001273-jbc.RA118.001273. https://doi.org/10.1074/jbc.RA118.001273.
    10.1074/jbc.RA118.001273
  60. Mariana González-Hernández; Markus Hoffmann; Constantin Brinkmann; Julia Nehls; Michael Winkler; Michael Schindler; Stefan Pöhlmann; Terence S. Dermody. "A GXXXA Motif in the Transmembrane Domain of the Ebola Virus Glycoprotein Is Required for Tetherin Antagonism". Journal of Virology 92 13 (2018): https://doi.org/10.1128/JVI.00403-18.
    10.1128/JVI.00403-18
  61. Hoffmann, M.; Pöhlmann, S.. "Cell Entry of Influenza A Viruses: Sweet Talk between HA and CaV1.2". Cell Host and Microbe 23 6 (2018): 697-699. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048635470&partnerID=MN8TOARS.
    10.1016/j.chom.2018.05.019
  62. Constantin Brinkmann; Paul Spearman; Markus Hoffmann; Anastasia Lübke; Inga Nehlmeier; Annika Krämer-Kühl; Michael Winkler; Stefan Pöhlmann. "The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cells". PLOS ONE 12 12 (2017): e0189073-e0189073. https://doi.org/10.1371/journal.pone.0189073.
    10.1371/journal.pone.0189073
  63. "Herpes B virus replication and viral lesions in the liver of a cynomolgus macaque which died from severe disease with rapid onset.". Journal of medical primatology (2017): http://europepmc.org/abstract/med/28439900.
    10.1111/jmp.12269
  64. "Dissecting Multivalent Lectin-Carbohydrate Recognition Using Polyvalent Multifunctional Glycan-Quantum Dots.". Journal of the American Chemical Society (2017): http://europepmc.org/abstract/med/28786666.
    10.1021/jacs.7b05104
  65. "pH Optimum of Hemagglutinin-Mediated Membrane Fusion Determines Sensitivity of Influenza A Viruses to the Interferon-Induced Antiviral State and IFITMs.". Journal of virology (2017): http://europepmc.org/abstract/med/28356532.
    10.1128/jvi.00246-17
  66. "A Polymorphism within the Internal Fusion Loop of the Ebola Virus Glycoprotein Modulates Host Cell Entry.". Journal of virology (2017): http://europepmc.org/abstract/med/28228590.
    10.1128/jvi.00177-17
  67. "Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins.". Journal of virology (2017): http://europepmc.org/abstract/med/27807233.
    10.1128/jvi.01488-16
  68. "Rhesus macaque IFITM3 gene polymorphisms and SIV infection.". PloS one (2017): http://europepmc.org/abstract/med/28257482.
    10.1371/journal.pone.0172847
  69. "Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin.". PloS one (2017): http://europepmc.org/abstract/med/28493964.
    10.1371/journal.pone.0176597
  70. "Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.". PloS one (2017): http://europepmc.org/abstract/med/28636671.
    10.1371/journal.pone.0179177
  71. Pöhlmann, S.; Krüger, A.; Hafezi, W.; Schneider, S.; Gruber, J.; Winkler, M.; Kaul, A.. "Detection systems for antibody responses against herpes B virus". Primate Biology 4 1 (2017): 9-16. http://www.scopus.com/inward/record.url?eid=2-s2.0-85063536995&partnerID=MN8TOARS.
    10.5194/pb-4-9-2017
  72. "The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies.". Journal of Virology (2016): http://europepmc.org/abstract/med/27707924.
    10.1128/jvi.01563-16
  73. "The Role of Phlebovirus Glycoproteins in Viral Entry, Assembly and Release". Viruses (2016): http://www.mdpi.com/1999-4915/8/7/202.
    10.3390/v8070202
  74. "The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases.". Journal of virology (2016): http://europepmc.org/abstract/med/26889029.
    10.1128/jvi.02693-15
  75. "Compact, Polyvalent Mannose Quantum Dots as Sensitive, Ratiometric FRET Probes for Multivalent Protein-Ligand Interactions.". Angewandte Chemie (International ed. in English) (2016): http://europepmc.org/abstract/med/26990806.
    10.1002/anie.201600593
  76. "Evidence that Processing of the Severe Fever with Thrombocytopenia Syndrome Virus Gn/Gc Polyprotein Is Critical for Viral Infectivity and Requires an Internal Gc Signal Peptide.". PloS one (2016): http://europepmc.org/abstract/med/27855227.
    10.1371/journal.pone.0166013
  77. "The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent.". PloS one (2016): http://europepmc.org/abstract/med/26901159.
    10.1371/journal.pone.0149651
  78. "The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells.". PloS one (2016): http://europepmc.org/abstract/med/27028521.
    10.1371/journal.pone.0152134
  79. "Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques.". Journal of Virology (2015): http://europepmc.org/abstract/med/26355090.
    10.1128/jvi.01358-15
  80. "Tetherin Sensitivity of Influenza A Viruses Is Strain Specific: Role of Hemagglutinin and Neuraminidase.". Journal of Virology (2015): http://europepmc.org/abstract/med/26109730.
    10.1128/jvi.00615-15
  81. Wrensch F; Karsten CB; Gnirß K; Hoffmann M; Lu K; Takada A; Winkler M; Simmons G; Pöhlmann S. "Interferon-Induced Transmembrane Protein-Mediated Inhibition of Host Cell Entry of Ebolaviruses.". (2015): http://europepmc.org/abstract/med/26034199.
  82. Zhou Y; Vedantham P; Lu K; Agudelo J; Carrion R Jr; Nunneley JW; Barnard D; et al. "Protease inhibitors targeting coronavirus and filovirus entry.". (2015): http://europepmc.org/abstract/med/25666761.
    10.1016/j.antiviral.2015.01.011
  83. Dahlmann F; Biedenkopf N; Babler A; Jahnen-Dechent W; Karsten CB; Gnirß K; Schneider H; et al. "Analysis of Ebola Virus Entry Into Macrophages.". (2015): http://europepmc.org/abstract/med/25877552.
    10.1093/infdis/jiv140
  84. Hofmann-Winkler H; Gnirß K; Wrensch F; Pöhlmann S. "Comparative Analysis of Host Cell Entry of Ebola Virus From Sierra Leone, 2014, and Zaire, 1976.". (2015): http://europepmc.org/abstract/med/25840443.
    10.1093/infdis/jiv101
  85. Gierer S; Müller MA; Heurich A; Ritz D; Springstein BL; Karsten CB; Schendzielorz A; et al. "Inhibition of proprotein convertases abrogates processing of the middle eastern respiratory syndrome coronavirus spike protein in infected cells but does not reduce viral infectivity.". (2015): http://europepmc.org/abstract/med/25057042.
    10.1093/infdis/jiu407
  86. "TMPRSS2 Isoform 1 Activates Respiratory Viruses and Is Expressed in Viral Target Cells.". PloS one (2015): http://europepmc.org/abstract/med/26379044.
    10.1371/journal.pone.0138380
  87. Wrensch, F.; Karsten, C.B.; Gnirß, K.; Hoffmann, M.; Lu, K.; Takada, A.; Winkler, M.; Simmons, G.; Pöhlmann, S.. "Interferon-Induced Transmembrane Protein-Mediated Inhibition of Host Cell Entry of Ebolaviruses". Journal of Infectious Diseases 212 (2015): S210-S218. http://www.scopus.com/inward/record.url?eid=2-s2.0-84943339110&partnerID=MN8TOARS.
    10.1093/infdis/jiv255
  88. Zmora P; Blazejewska P; Moldenhauer AS; Welsch K; Nehlmeier I; Wu Q; Schneider H; Pöhlmann S; Bertram S. "DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.". (2014): http://europepmc.org/abstract/med/25122802.
    10.1128/JVI.01427-14
  89. Wrensch F; Winkler M; Pöhlmann S. "IFITM proteins inhibit entry driven by the MERS-coronavirus spike protein: evidence for cholesterol-independent mechanisms.". (2014): http://europepmc.org/abstract/med/25256397.
    10.3390/v6093683
  90. Gehring G; Rohrmann K; Atenchong N; Mittler E; Becker S; Dahlmann F; Pöhlmann S; et al. "The clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry.". (2014): http://europepmc.org/abstract/med/24710028.
    10.1093/jac/dku091
  91. Van Breedam W; Pöhlmann S; Favoreel HW; de Groot RJ; Nauwynck HJ. "Bitter-sweet symphony: glycan-lectin interactions in virus biology.". (2014): http://europepmc.org/abstract/med/24188132.
    10.1111/1574-6976.12052
  92. Gnirß K; Fiedler M; Krämer-Kühl A; Bolduan S; Mittler E; Becker S; Schindler M; Pöhlmann S. "Analysis of determinants in filovirus glycoproteins required for tetherin antagonism.". (2014): http://europepmc.org/abstract/med/24721789.
    10.3390/v6041654
  93. Heurich A; Hofmann-Winkler H; Gierer S; Liepold T; Jahn O; Pöhlmann S. "TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein.". (2014): http://europepmc.org/abstract/med/24227843.
    10.1128/JVI.02202-13
  94. Kiene M; Rethi B; Jansson M; Dillon S; Lee E; Lantto R; Wilson C; Pöhlmann S; Chiodi F. "Toll-like receptor 3 signalling up-regulates expression of the HIV co-receptor G-protein coupled receptor 15 on human CD4+ T cells.". (2014): http://europepmc.org/abstract/med/24558379.
    10.1371/journal.pone.0088195
  95. Eckert N; Wrensch F; Gärtner S; Palanisamy N; Goedecke U; Jäger N; Pöhlmann S; Winkler M. "Influenza A virus encoding secreted Gaussia luciferase as useful tool to analyze viral replication and its inhibition by antiviral compounds and cellular proteins.". (2014): http://europepmc.org/abstract/med/24842154.
    10.1371/journal.pone.0097695
  96. Gierer S; Hofmann-Winkler H; Albuali WH; Bertram S; Al-Rubaish AM; Yousef AA; Al-Nafaie AN; et al. "Lack of MERS coronavirus neutralizing antibodies in humans, eastern province, Saudi Arabia.". (2013): http://europepmc.org/abstract/med/24274664.
    10.3201/eid1912.130701
  97. Simmons G; Zmora P; Gierer S; Heurich A; Pöhlmann S. "Proteolytic activation of the SARS-coronavirus spike protein: cutting enzymes at the cutting edge of antiviral research.". (2013): http://europepmc.org/abstract/med/24121034.
    10.1016/j.antiviral.2013.09.028
  98. Bertram S; Dijkman R; Habjan M; Heurich A; Gierer S; Glowacka I; Welsch K; et al. "TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium.". (2013): http://europepmc.org/abstract/med/23536651.
    10.1128/JVI.03372-12
  99. Gierer S; Bertram S; Kaup F; Wrensch F; Heurich A; Krämer-Kühl A; Welsch K; et al. "The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies.". (2013): http://europepmc.org/abstract/med/23468491.
    10.1128/JVI.00128-13
  100. Hofmann H; Li X; Zhang X; Liu W; Kühl A; Kaup F; Soldan SS; et al. "Severe fever with thrombocytopenia virus glycoproteins are targeted by neutralizing antibodies and can use DC-SIGN as a receptor for pH-dependent entry into human and animal cell lines.". (2013): http://europepmc.org/abstract/med/23388721.
    10.1128/JVI.02628-12
  101. Lindemann D; Steffen I; Pöhlmann S. "Cellular entry of retroviruses.". (2013): http://europepmc.org/abstract/med/23884589.
    10.1007/978-1-4614-7651-1_7
  102. Solomon Tsegaye T; Gnirß K; Rahe-Meyer N; Kiene M; Krämer-Kühl A; Behrens G; Münch J; Pöhlmann S. "Platelet activation suppresses HIV-1 infection of T cells.". (2013): http://europepmc.org/abstract/med/23634812.
    10.1186/1742-4690-10-48
  103. "Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.". PLoS Pathogens (2013): http://europepmc.org/abstract/med/24348248.
    10.1371/journal.ppat.1003774
  104. Hofmann-Winkler H; Kaup F; Pöhlmann S. "Host cell factors in filovirus entry: novel players, new insights.". (2012): http://europepmc.org/abstract/med/23342362.
    10.3390/v4123336
  105. Kiene M; Marzi A; Urbanczyk A; Bertram S; Fisch T; Nehlmeier I; Gnirss K; et al. "The role of the alternative coreceptor GPR15 in SIV tropism for human cells.". (2012): http://europepmc.org/abstract/med/22874069.
    10.1016/j.virol.2012.07.012
  106. Kühl A; Pöhlmann S. "How Ebola virus counters the interferon system.". (2012): http://europepmc.org/abstract/med/22958256.
    10.1111/j.1863-2378.2012.01454.x
  107. Gnirss K; Kühl A; Karsten C; Glowacka I; Bertram S; Kaup F; Hofmann H; Pöhlmann S. "Cathepsins B and L activate Ebola but not Marburg virus glycoproteins for efficient entry into cell lines and macrophages independent of TMPRSS2 expression.". (2012): http://europepmc.org/abstract/med/22222211.
    10.1016/j.virol.2011.11.031
  108. Pritschet K; Donhauser N; Schuster P; Ries M; Haupt S; Kittan NA; Korn K; et al. "CD4- and dynamin-dependent endocytosis of HIV-1 into plasmacytoid dendritic cells.". (2012): http://europepmc.org/abstract/med/22209232.
    10.1016/j.virol.2011.11.026
  109. Winkler M; Bertram S; Gnirß K; Nehlmeier I; Gawanbacht A; Kirchhoff F; Ehrhardt C; et al. "Influenza A virus does not encode a tetherin antagonist with Vpu-like activity and induces IFN-dependent tetherin expression in infected cells.". (2012): http://europepmc.org/abstract/med/22952667.
    10.1371/journal.pone.0043337
  110. Bertram S; Heurich A; Lavender H; Gierer S; Danisch S; Perin P; Lucas JM; et al. "Influenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts.". (2012): http://europepmc.org/abstract/med/22558251.
    10.1371/journal.pone.0035876
  111. Bertram S; Glowacka I; Müller MA; Lavender H; Gnirss K; Nehlmeier I; Niemeyer D; et al. "Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease.". (2011): http://europepmc.org/abstract/med/21994442.
    10.1128/JVI.05300-11
  112. Kühl A; Banning C; Marzi A; Votteler J; Steffen I; Bertram S; Glowacka I; et al. "The Ebola virus glycoprotein and HIV-1 Vpu employ different strategies to counteract the antiviral factor tetherin.". (2011): http://europepmc.org/abstract/med/21987761.
    10.1093/infdis/jir378
  113. Kühl A; Hoffmann M; Müller MA; Munster VJ; Gnirss K; Kiene M; Tsegaye TS; et al. "Comparative analysis of Ebola virus glycoprotein interactions with human and bat cells.". (2011): http://europepmc.org/abstract/med/21987760.
    10.1093/infdis/jir306
  114. Pfefferle S; Schöpf J; Kögl M; Friedel CC; Müller MA; Carbajo-Lozoya J; Stellberger T; et al. "The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors.". (2011): http://europepmc.org/abstract/med/22046132.
    10.1371/journal.ppat.1002331
  115. Hofmann H; Pöhlmann S. "DC-SIGN: access portal for sweet viral killers.". (2011): http://europepmc.org/abstract/med/21767807.
    10.1016/j.chom.2011.07.003
  116. Pipirou Z; Powlesland AS; Steffen I; Pöhlmann S; Taylor ME; Drickamer K. "Mouse LSECtin as a model for a human Ebola virus receptor.". (2011): http://europepmc.org/abstract/med/21257728.
    10.1093/glycob/cwr008
  117. Glowacka I; Bertram S; Müller MA; Allen P; Soilleux E; Pfefferle S; Steffen I; et al. "Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response.". (2011): http://europepmc.org/abstract/med/21325420.
    10.1128/JVI.02232-10
  118. Simmons G; Bertram S; Glowacka I; Steffen I; Chaipan C; Agudelo J; Lu K; et al. "Different host cell proteases activate the SARS-coronavirus spike-protein for cell-cell and virus-cell fusion.". (2011): http://europepmc.org/abstract/med/21435673.
    10.1016/j.virol.2011.02.020
  119. Tsegaye TS; Pöhlmann S. "The multiple facets of HIV attachment to dendritic cell lectins.". (2010): http://europepmc.org/abstract/med/20854332.
    10.1111/j.1462-5822.2010.01519.x
  120. Bertram S; Glowacka I; Blazejewska P; Soilleux E; Allen P; Danisch S; Steffen I; et al. "TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza virus in Caco-2 cells.". (2010): http://europepmc.org/abstract/med/20631123.
    10.1128/JVI.00239-10
  121. Zhou Y; Lu K; Pfefferle S; Bertram S; Glowacka I; Drosten C; Pöhlmann S; Simmons G. "A single asparagine-linked glycosylation site of the severe acute respiratory syndrome coronavirus spike glycoprotein facilitates inhibition by mannose-binding lectin through multiple mechanisms.". (2010): http://europepmc.org/abstract/med/20573835.
    10.1128/JVI.00554-10
  122. Bertram S; Glowacka I; Steffen I; Kühl A; Pöhlmann S. "Novel insights into proteolytic cleavage of influenza virus hemagglutinin.". (2010): http://europepmc.org/abstract/med/20629046.
    10.1002/rmv.657
  123. Kühl A; Münch J; Sauter D; Bertram S; Glowacka I; Steffen I; Specht A; et al. "Calcium-modulating cyclophilin ligand does not restrict retrovirus release.". (2010): http://europepmc.org/abstract/med/20134461.
    10.1038/nm0210-155
  124. Glowacka I; Bertram S; Herzog P; Pfefferle S; Steffen I; Muench MO; Simmons G; et al. "Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63.". (2010): http://europepmc.org/abstract/med/19864379.
    10.1128/JVI.01248-09
  125. Chaipan C; Steffen I; Tsegaye TS; Bertram S; Glowacka I; Kato Y; Schmökel J; et al. "Incorporation of podoplanin into HIV released from HEK-293T cells, but not PBMC, is required for efficient binding to the attachment factor CLEC-2.". (2010): http://europepmc.org/abstract/med/20482880.
    10.1186/1742-4690-7-47
  126. Steffen I; Pöhlmann S. "Peptide-based inhibitors of the HIV envelope protein and other class I viral fusion proteins.". (2010): http://europepmc.org/abstract/med/20030613.
    10.2174/138161210790963751
  127. Choi SY; Bertram S; Glowacka I; Park YW; Pöhlmann S. "Type II transmembrane serine proteases in cancer and viral infections.". (2009): http://europepmc.org/abstract/med/19581128.
    10.1016/j.molmed.2009.05.003
  128. Chaipan C; Kobasa D; Bertram S; Glowacka I; Steffen I; Tsegaye TS; Takeda M; et al. "Proteolytic activation of the 1918 influenza virus hemagglutinin.". (2009): http://europepmc.org/abstract/med/19158246.
    10.1128/JVI.02205-08
  129. Gramberg T; Soilleux E; Fisch T; Lalor PF; Hofmann H; Wheeldon S; Cotterill A; et al. "Interactions of LSECtin and DC-SIGN/DC-SIGNR with viral ligands: Differential pH dependence, internalization and virion binding.". (2008): http://europepmc.org/abstract/med/18083206.
    10.1016/j.virol.2007.11.001
  130. Powlesland AS; Fisch T; Taylor ME; Smith DF; Tissot B; Dell A; Pöhlmann S; Drickamer K. "A novel mechanism for LSECtin binding to Ebola virus surface glycoprotein through truncated glycans.". (2008): http://europepmc.org/abstract/med/17984090.
    10.1074/jbc.M706292200
  131. Pöhlmann, S.. "Carbohydrates on HIV: mediators of immune evasion and targets for antiviral intervention". Future HIV Therapy 2 3 (2008): 253-257. http://www.scopus.com/inward/record.url?eid=2-s2.0-52349091831&partnerID=MN8TOARS.
    10.2217/17469600.2.3.253
  132. Marzi A; Möller P; Hanna SL; Harrer T; Eisemann J; Steinkasserer A; Becker S; Baribaud F; Pöhlmann S. "Analysis of the interaction of Ebola virus glycoprotein with DC-SIGN (dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin) and its homologue DC-SIGNR.". (2007): http://europepmc.org/abstract/med/17940955.
    10.1086/520607
  133. Marzi A; Mitchell DA; Chaipan C; Fisch T; Doms RW; Carrington M; Desrosiers RC; Pöhlmann S. "Modulation of HIV and SIV neutralization sensitivity by DC-SIGN and mannose-binding lectin.". (2007): http://europepmc.org/abstract/med/17659761.
    10.1016/j.virol.2007.07.004
  134. Pöhlmann S; Münch J; Aziz S; Reeves JD; Otto C; Leslie GJ; Hofmann H; et al. "A simian immunodeficiency virus V3 loop mutant that does not efficiently use CCR5 or common alternative coreceptors is moderately attenuated in vivo.". (2007): http://europepmc.org/abstract/med/17126374.
    10.1016/j.virol.2006.10.020
  135. Fuller GL; Williams JA; Tomlinson MG; Eble JA; Hanna SL; Pöhlmann S; Suzuki-Inoue K; et al. "The C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signaling cascade.". (2007): http://europepmc.org/abstract/med/17339324.
    10.1074/jbc.M609558200
  136. Münch J; Ständker L; Adermann K; Schulz A; Schindler M; Chinnadurai R; Pöhlmann S; et al. "Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide.". (2007): http://europepmc.org/abstract/med/17448989.
    10.1016/j.cell.2007.02.042
  137. Marzi A; Wegele A; Pöhlmann S. "Modulation of virion incorporation of Ebolavirus glycoprotein: effects on attachment, cellular entry and neutralization.". (2006): http://europepmc.org/abstract/med/16777170.
    10.1016/j.virol.2006.04.038
  138. Chaipan C; Soilleux EJ; Simpson P; Hofmann H; Gramberg T; Marzi A; Geier M; et al. "DC-SIGN and CLEC-2 mediate human immunodeficiency virus type 1 capture by platelets.". (2006): http://europepmc.org/abstract/med/16940507.
    10.1128/JVI.00136-06
  139. Hofmann H; Simmons G; Rennekamp AJ; Chaipan C; Gramberg T; Heck E; Geier M; et al. "Highly conserved regions within the spike proteins of human coronaviruses 229E and NL63 determine recognition of their respective cellular receptors.". (2006): http://europepmc.org/abstract/med/16912312.
    10.1128/JVI.00560-06
  140. Marzi A; Akhavan A; Simmons G; Gramberg T; Hofmann H; Bates P; Lingappa VR; Pöhlmann S. "The signal peptide of the ebolavirus glycoprotein influences interaction with the cellular lectins DC-SIGN and DC-SIGNR.". (2006): http://europepmc.org/abstract/med/16775318.
    10.1128/JVI.02545-05
  141. Caminschi I; Corbett AJ; Zahra C; Lahoud M; Lucas KM; Sofi M; Vremec D; et al. "Functional comparison of mouse CIRE/mouse DC-SIGN and human DC-SIGN.". (2006): http://europepmc.org/abstract/med/16569675.
    10.1093/intimm/dxl011
  142. Gramberg T; Zhu T; Chaipan C; Marzi A; Liu H; Wegele A; Andrus T; Hofmann H; Pöhlmann S. "Impact of polymorphisms in the DC-SIGNR neck domain on the interaction with pathogens.". (2006): http://europepmc.org/abstract/med/16413044.
    10.1016/j.virol.2005.11.033
  143. Gramberg T; Caminschi I; Wegele A; Hofmann H; Pöhlmann S. "Evidence that multiple defects in murine DC-SIGN inhibit a functional interaction with pathogens.". (2006): http://europepmc.org/abstract/med/16297949.
    10.1016/j.virol.2005.10.008
  144. Suzuki-Inoue K; Fuller GL; García A; Eble JA; Pöhlmann S; Inoue O; Gartner TK; et al. "A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.". (2006): http://europepmc.org/abstract/med/16174766.
    10.1182/blood-2005-05-1994
  145. Pöhlmann S; Gramberg T; Wegele A; Pyrc K; van der Hoek L; Berkhout B; Hofmann H. "Interaction between the spike protein of human coronavirus NL63 and its cellular receptor ACE2.". (2006): http://europepmc.org/abstract/med/17037543.
  146. Hofmann H; Marzi A; Gramberg T; Geier M; Pyrc K; van der Hoek L; Berkhout B; Pöhlmann S. "Attachment factor and receptor engagement of SARS coronavirus and human coronavirus NL63.". (2006): http://europepmc.org/abstract/med/17037533.
  147. Pöhlmann S; Reeves JD. "Cellular entry of HIV: Evaluation of therapeutic targets.". (2006): http://europepmc.org/abstract/med/16787241.
    10.2174/138161206777442155
  148. Gramberg T; Hofmann H; Möller P; Lalor PF; Marzi A; Geier M; Krumbiegel M; et al. "LSECtin interacts with filovirus glycoproteins and the spike protein of SARS coronavirus.". (2005): http://europepmc.org/abstract/med/16051304.
    10.1016/j.virol.2005.06.026
  149. Hofmann H; Pyrc K; van der Hoek L; Geier M; Berkhout B; Pöhlmann S. "Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry.". (2005): http://europepmc.org/abstract/med/15897467.
    10.1073/pnas.0409465102
  150. Marzi A; Gramberg T; Simmons G; Möller P; Rennekamp AJ; Krumbiegel M; Geier M; et al. "DC-SIGN and DC-SIGNR interact with the glycoprotein of Marburg virus and the S protein of severe acute respiratory syndrome coronavirus.". (2004): http://europepmc.org/abstract/med/15479853.
    10.1128/JVI.78.21.12090-12095.2004
  151. Hofmann H; Pöhlmann S. "Cellular entry of the SARS coronavirus.". (2004): http://europepmc.org/abstract/med/15381196.
    10.1016/j.tim.2004.08.008
  152. Hofmann H; Geier M; Marzi A; Krumbiegel M; Peipp M; Fey GH; Gramberg T; Pöhlmann S. "Susceptibility to SARS coronavirus S protein-driven infection correlates with expression of angiotensin converting enzyme 2 and infection can be blocked by soluble receptor.". (2004): http://europepmc.org/abstract/med/15194496.
    10.1016/j.bbrc.2004.05.114
  153. Hiebenthal-Millow K; Pöhlmann S; Münch J; Kirchhoff F. "Differential regulation of human immunodeficiency virus type 2 and simian immunodeficiency virus promoter activity.". (2004): http://europepmc.org/abstract/med/15207635.
    10.1016/j.virol.2004.04.007
  154. Hofmann H; Hattermann K; Marzi A; Gramberg T; Geier M; Krumbiegel M; Kuate S; et al. "S protein of severe acute respiratory syndrome-associated coronavirus mediates entry into hepatoma cell lines and is targeted by neutralizing antibodies in infected patients.". (2004): http://europepmc.org/abstract/med/15163706.
    10.1128/JVI.78.12.6134-6142.2004
  155. Pöhlmann S; Davis C; Meister S; Leslie GJ; Otto C; Reeves JD; Puffer BA; et al. "Amino acid 324 in the simian immunodeficiency virus SIVmac V3 loop can confer CD4 independence and modulate the interaction with CCR5 and alternative coreceptors.". (2004): http://europepmc.org/abstract/med/15016843.
    10.1128/JVI.78.7.3223-3232.2004
  156. Pierson TC; Doms RW; Pöhlmann S. "Prospects of HIV-1 entry inhibitors as novel therapeutics.". (2004): http://europepmc.org/abstract/med/15248253.
    10.1002/rmv.435
  157. Otto C; Puffer BA; Pöhlmann S; Doms RW; Kirchhoff F. "Mutations in the C3 region of human and simian immunodeficiency virus envelope have differential effects on viral infectivity, replication, and CD4-dependency.". (2003): http://europepmc.org/abstract/med/14585332.
    10.1016/S0042-6822(03)00513-0
  158. Pöhlmann S; Zhang J; Baribaud F; Chen Z; Leslie GJ; Lin G; Granelli-Piperno A; et al. "Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR.". (2003): http://europepmc.org/abstract/med/12634366.
    10.1128/JVI.77.7.4070-4080.2003
  159. Simmons G; Reeves JD; Grogan CC; Vandenberghe LH; Baribaud F; Whitbeck JC; Burke E; et al. "DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells.". (2003): http://europepmc.org/abstract/med/12504546.
    10.1006/viro.2002.1730
  160. Lin G; Simmons G; Pöhlmann S; Baribaud F; Ni H; Leslie GJ; Haggarty BS; et al. "Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNR.". (2003): http://europepmc.org/abstract/med/12502850.
    10.1128/JVI.77.2.1337-1346.2003
  161. Reeves JD; Gallo SA; Ahmad N; Miamidian JL; Harvey PE; Sharron M; Pohlmann S; et al. "Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics.". (2002): http://europepmc.org/abstract/med/12444251.
    10.1073/pnas.252469399
  162. Turville SG; Cameron PU; Handley A; Lin G; Pöhlmann S; Doms RW; Cunningham AL. "Diversity of receptors binding HIV on dendritic cell subsets.". (2002): http://europepmc.org/abstract/med/12352970.
    10.1038/ni841
  163. Baribaud F; Pöhlmann S; Leslie G; Mortari F; Doms RW. "Quantitative expression and virus transmission analysis of DC-SIGN on monocyte-derived dendritic cells.". (2002): http://europepmc.org/abstract/med/12186897.
    10.1128/JVI.76.18.9135-9142.2002
  164. Baribaud F; Doms RW; Pöhlmann S. "The role of DC-SIGN and DC-SIGNR in HIV and Ebola virus infection: can potential therapeutics block virus transmission and dissemination?". (2002): http://europepmc.org/abstract/med/12223058.
    10.1517/14728222.6.4.423
  165. Münch J; Ständker L; Pöhlmann S; Baribaud F; Papkalla A; Rosorius O; Stauber R; et al. "Hemofiltrate CC chemokine 1[9-74] causes effective internalization of CCR5 and is a potent inhibitor of R5-tropic human immunodeficiency virus type 1 strains in primary T cells and macrophages.". (2002): http://europepmc.org/abstract/med/11897579.
    10.1128/AAC.46.4.982-990.2002
  166. Pöhlmann S; Doms RW. "Evaluation of current approaches to inhibit HIV entry.". (2002): http://europepmc.org/abstract/med/12462149.
    10.2174/1568005024605864
  167. Puffer BA; Pöhlmann S; Edinger AL; Carlin D; Sanchez MD; Reitter J; Watry DD; et al. "CD4 independence of simian immunodeficiency virus Envs is associated with macrophage tropism, neutralization sensitivity, and attenuated pathogenicity.". (2002): http://europepmc.org/abstract/med/11861825.
    10.1128/JVI.76.6.2595-2605.2002
  168. Jameson B; Baribaud F; Pöhlmann S; Ghavimi D; Mortari F; Doms RW; Iwasaki A. "Expression of DC-SIGN by dendritic cells of intestinal and genital mucosae in humans and rhesus macaques.". (2002): http://europepmc.org/abstract/med/11799181.
    10.1128/JVI.76.4.1866-1875.2002
  169. Pöhlmann S; Baribaud F; Doms RW. "DC-SIGN and DC-SIGNR: helping hands for HIV.". (2001): http://europepmc.org/abstract/med/11738974.
    10.1016/S1471-4906(01)02081-6
  170. Soilleux EJ; Morris LS; Lee B; Pöhlmann S; Trowsdale J; Doms RW; Coleman N. "Placental expression of DC-SIGN may mediate intrauterine vertical transmission of HIV.". (2001): http://europepmc.org/abstract/med/11745695.
    10.1002/path.1026
  171. Baribaud F; Pöhlmann S; Sparwasser T; Kimata MT; Choi YK; Haggarty BS; Ahmad N; et al. "Functional and antigenic characterization of human, rhesus macaque, pigtailed macaque, and murine DC-SIGN.". (2001): http://europepmc.org/abstract/med/11581396.
    10.1128/JVI.75.21.10281-10289.2001
  172. Pöhlmann S; Leslie GJ; Edwards TG; Macfarlan T; Reeves JD; Hiebenthal-Millow K; Kirchhoff F; Baribaud F; Doms RW. "DC-SIGN interactions with human immunodeficiency virus: virus binding and transfer are dissociable functions.". (2001): http://europepmc.org/abstract/med/11581425.
    10.1128/JVI.75.21.10523-10526.2001
  173. Baribaud F; Pöhlmann S; Doms RW. "The role of DC-SIGN and DC-SIGNR in HIV and SIV attachment, infection, and transmission.". (2001): http://europepmc.org/abstract/med/11448153.
    10.1006/viro.2001.0975
  174. Meister S; Otto C; Papkalla A; Krumbiegel M; Pöhlmann S; Kirchhoff F. "Basic amino acid residues in the V3 loop of simian immunodeficiency virus envelope alter viral coreceptor tropism and infectivity but do not allow efficient utilization of CXCR4 as entry cofactor.". (2001): http://europepmc.org/abstract/med/11384227.
    10.1006/viro.2001.0852
  175. Pöhlmann S; Baribaud F; Lee B; Leslie GJ; Sanchez MD; Hiebenthal-Millow K; Münch J; Kirchhoff F; Doms RW. "DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus.". (2001): http://europepmc.org/abstract/med/11312337.
    10.1128/JVI.75.10.4664-4672.2001
  176. Pöhlmann S; Soilleux EJ; Baribaud F; Leslie GJ; Morris LS; Trowsdale J; Lee B; Coleman N; Doms RW. "DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans.". (2001): http://europepmc.org/abstract/med/11226297.
    10.1073/pnas.051631398
  177. Detheux M; Ständker L; Vakili J; Münch J; Forssmann U; Adermann K; Pöhlmann S; et al. "Natural proteolytic processing of hemofiltrate CC chemokine 1 generates a potent CC chemokine receptor (CCR)1 and CCR5 agonist with anti-HIV properties.". (2000): http://europepmc.org/abstract/med/11085751.
    10.1084/jem.192.10.1501
  178. Sharron M; Pöhlmann S; Price K; Lolis E; Tsang M; Kirchhoff F; Doms RW; Lee B. "Expression and coreceptor activity of STRL33/Bonzo on primary peripheral blood lymphocytes.". (2000): http://europepmc.org/abstract/med/10891428.
  179. Pöhlmann S; Lee B; Meister S; Krumbiegel M; Leslie G; Doms RW; Kirchhoff F. "Simian immunodeficiency virus utilizes human and sooty mangabey but not rhesus macaque STRL33 for efficient entry.". (2000): http://europepmc.org/abstract/med/10799581.
    10.1128/JVI.74.11.5075-5082.2000
  180. Pöhlmann, S.; Stolte, N.; Münch, J.; Ten Haaft, P.; Heeney, J.L.; Stahl-Hennig, C.; Kirchhoff, F.. "Co-receptor usage of BOB/GPR15 in addition to CCR5 has no significant effect on replication of simian immunodeficiency virus in vivo". Journal of Infectious Diseases 180 5 (1999): 1494-1502. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032703757&partnerID=MN8TOARS.
    10.1086/315097
  181. Pöhlmann S; Flöss S; Ilyinskii PO; Stamminger T; Kirchhoff F. "Sequences just upstream of the simian immunodeficiency virus core enhancer allow efficient replication in the absence of NF-kappaB and Sp1 binding elements.". (1998): http://europepmc.org/abstract/med/9621017.
  182. Kirchhoff F; Pöhlmann S; Hamacher M; Means RE; Kraus T; Uberla K; Di Marzio P. "Simian immunodeficiency virus variants with differential T-cell and macrophage tropism use CCR5 and an unidentified cofactor expressed in CEMx174 cells for efficient entry.". (1997): http://europepmc.org/abstract/med/9261370.
Capítulo de livro
  1. Hoffmann, M.; Hofmann-Winkler, H.; Pöhlmann, S.. "Priming time: How cellular proteases arm coronavirus spike proteins". 71-98. 2018.
Livro
  1. Pohlmann, S.; Simmons, G.. Preface. 2013.
  2. Glowacka, I.; Bertram, S.; Pöhlmann, S.. Cellular entry of the SARS coronavirus: Implications for transmission, pathogenicity and antiviral strategies. 2010.
  3. Steffen, I.; Tsegaye, T.S.; Pöhlmann, S.. Lectin-Like Interactions in Virus-Cell Recognition: Human Immunodeficiency Virus and C-Type Lectin Interactions. 2010.
  4. Pöhlmann, S.. Interactions of Hemorrhagic Fever Viruses with Dendritic Cells. 2008.
  5. Reeves, J.D.; Barr, S.D.; Pöhlmann, S.. Evaluation of current strategies to inhibit HIV entry, integration and maturation. 2006.
  6. Hofmann, H.; Marzi, A.; Gramberg, T.; Geier, M.; Pyrc, K.; Van Der Hoek, L.; Berkhout, B.; Pöhlmann, S.. Attachment factor and receptor engagement of SARS coronavirus and human coronavirus NL63. 2006.
    10.1007/978-0-387-33012-9_37
  7. Pöhlmann, S.; Gramberg, T.; Wegele, A.; Pyrc, K.; Van Der Hoek, L.; Berkhout, B.; Hofmann, H.. Interaction between the spike protein of human coronavirus NL63 and its cellular receptor ACE2. 2006.
    10.1007/978-0-387-33012-9_47

Outros

Outra produção
  1. Probing Multivalent Lectin-Carbohydrate Binding via Multifunctional Glycan-Gold Nanoparticles: Implications for Blocking Virus Infection. 2020. Darshita Budhadev; Emma Poole; Inga Nehlmeier; Yuanyuan Liu; James Hooper; Elizabeth Kalverda; Uchangi Satyaprasad Akshath; et al. https://doi.org/10.26434/chemrxiv.12573701.v1.
    10.26434/chemrxiv.12573701.v1
  2. The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells. 2020. Markus Hoffmann; Hannah Kleine-Weber; Nadine Krüger; Marcel Müller; Christian Drosten; Stefan Pöhlmann. https://doi.org/10.1101/2020.01.31.929042.
    10.1101/2020.01.31.929042
  3. Evidence for influenza B virus hemagglutinin adaptation to the human host: high cleavability, acid-stability and preference for cool temperature. 2019. Manon Laporte; Annelies Stevaert; Valerie Raeymaekers; Talitha Boogaerts; Inga Nehlmeier; Winston Chiu; Mohammed Benkheil; et al. https://doi.org/10.1101/736678.
    10.1101/736678
  4. Development and use of Lentiviral Vectors Pseudotyped with Influenza B Haemagglutinins: application to vaccine immunogenicity, mAb potency and sero-surveillance studies. 2018. Ferrara F; Carnell G; Kinsley R; Bottcher-Friebertshauser E; Pohlmann S; Scott S; Fereidouni S; et al. http://europepmc.org/abstract/PPR/PPR64405.
    10.1101/492785