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Sofia Azeredo Gaspar Pereira (SAP) completed her PhD in Pharmacology (2010) and is Associated Professor with aggregation at NOVA Medical School, NMS Universidade Nova de Lisboa. She is/has been Vice-director of the PhD Program in Biomedicine, Coordinator of the Therapeutic Drug Monitoring and Responsible for the Analytical Facility. She is a researcher at iNOVA4Health FCT Research Unit. SAP is a pharmacologist and the head of the Renal, Cardiovascular and Metabolic Pharmacology lab at NOVA Medical School. SAP leads a research in close colaboration with 2 Main Hospital Centers in Lisboan affiliated to NMS - ULSO e ULS Jão José in biomarkers and clinical pharmacology studies for better outcomes. She lead pio pioneer work in finding a novel target in resistant hypertension associated with sleep apnea. SAP research fous AhR as a druggable target in cardiovascular-renal disease spectrum. She investigates AhR involvement in fibrosis and metabolic adaptations to microenvironmental conditions. She also lead pioneer work showing the relation between fibrosis of the peritoneal membrane and ocorrunce of MAjor Cardiovascula events. Her team has also being involved with engeneering groups to find point-of-care sensors to better managment of Renal disease. SAP is/has been a member of two European networks on hypertension and Kidney disease; she integrates the network Pharmacological regulation of NRF2 in non communicable diseases; She is a member of the working group translational nephrology at the Portuguese Society of Nephrology; She is/has been PI of a patent of a compound to treat diseases associated with HDL-dysfunction; member of the team of 2 clinical trials Her team has identified mechanisms of toxicity for 5 drugs and a biomarker of kidney disease progression conducting research in experimental models ( rodents, zebra fish, 3D cell culture) and clinical studies. She has been collaborating (since 2001) with Clinical Teams from Hospitals in Lisbon Area, with several common publications. Applying a mechanistically-oriented approach, Sofia´s team has identified populations of patients that are at higher risk for adverse drug reactions towards precision therapy (eg. gender differences, menopause).
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Identificação

Identificação pessoal

Nome completo
Sofia Azeredo Gaspar Pereira

Nomes de citação

  • Pereira, Sofia A.

Identificadores de autor

Ciência ID
6B13-7601-73A2
ORCID iD
0000-0002-8456-9995
Google Scholar ID
https://scholar.google.com.br/citations?user=UJ6bS8QAAAAJ&hl=pt-PT&authuser=1
Scopus Author Id
35190948700

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2022/12
Concluído
 Aggregated in Health Sciences, Biomedicine (Título de Agregado)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2011 - 2011
Concluído
 Pos doctoral, Netherlands, Training on LC-MS methodologies (Pós-doutoramento)
Slotervaart Hospital - Department of Pharmacy & Pharmacology, Países Baixos
2010/03/03 - 2010/09/06
Concluído
 USA, NCTR, Postdoctoral Training in Epigenetics/Toxicology (Pós-doutoramento)
National Center for Toxicological Research, Estados Unidos
2006/01 - 2010/01/14
Concluído
 Pharmacology (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
"Monitorização das concentrações plasmáticas de efavirenz: critérios de aplicabilidade à prática clínica e efeitos do fármaco a longo termo/Therapeutic drug monitoring of Efavirenz: criteria and long-term drug effects" (TESE/DISSERTAÇÃO)
 Maximal
2002 - 2002
Concluído
 Short-term formation - Quantification of drugs by HPLC (Outros)
Hospital Clínic de Barcelona, Espanha
2001 - 2002
Concluído
 Graduation Thesis: Development and validation of a HPLC method to quantify efavirenz plasma concentration in HIV-infected patients (Outros)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2002
Concluído
 Bioquímica (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2011/03/01 - 2011/10/09 Pós-doutorado (Investigação) MC Slotervaart, Países Baixos
MC Slotervaart, Países Baixos
2010/05/01 - 2010/08/06 Pós-doutorado (Investigação) National Center for Toxicological Research, Estados Unidos

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2024/01 - Atual Professor Associado (Docente Universitário) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2012 - 2022 Professor Auxiliar (Docente Universitário) Universidade Nova de Lisboa, Portugal
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/02 - Atual Group Leader at Renal, Cardiovascular and Metabolic Pharmacology lab Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2022/01 - Atual Head of Pharmacology 1 Integrated Master in Medicine Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019 - Atual Coordinator of the Pedagogic Comission of the 2nd year of the Integrated Master Degree in Medicine Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2018 - Atual Vice-director of the PhD Program in Biomedicine Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2016 - Atual Responsible for the Analytical Facility Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2014 - Atual Coordinator of the Therapeutic Drug Monitoring Unit Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019 - 2022 Head of the Curricular Unit "General Pharmacology" of the Integrated Master degree in Medicine Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2018 - 2021 Head of the Curricular Unit "Aging and chronic diseases: from molecular mechanisms to therapies" of the Master's Degree NOVA Biomedical Research Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2022 - Atual Assistant Professor with aggregation in Health Sciences, Biomedicine Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2021 - Atual co-Group Leader at iNOVA4Health FCT Research Unit Cardiometabolic diseases Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
2019 - 2021 co-Group Leader Translational Pharmacology lab Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2006/10/02 - 2010/01/14 PhD student Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2002/10/01 - 2002/11/01 Research fellow Hospital Clínic de Barcelona, Espanha
2001/10/01 - 2002/03/31 PRODEPT grant graduationThesis Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Projetos

Bolsa

Designação Financiadores
2024 - Atual Precision Urology: Metabolic Phenotype of patients with Metabolic Syndrome Traits and Recurrent Nephrolithiasis -Metabolomics and Recurrence Assessement
FFI31/2024
Investigador responsável
Em curso
2002 - 2003 Clinical efficacy and therapeutic drug monitoring of antiretroviral drugs in HIV infected patients taking rifamycins
POCTI/FCB/42664/2001
Bolseiro de Investigação
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2001 - 2002 Development and validation of a HPLC method to quantify efavirenz plasma concentration in HIV-infected patients
PRODEPT
Bolseiro de Investigação
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Concluído

Projeto

Designação Financiadores
2023/09/01 - Atual Life Sciences for a Healthy and Sustainable Future
LA/P/0087/2020
10.54499/LA/P/0087/2020
Universidade Nova de Lisboa Molecular Structural and Cellular Microbiology, Portugal

Universidade Nova de Lisboa, Portugal

GREEN-IT, Portugal

Instituto de Biologia Experimental e Tecnológica, Portugal

Instituto Gulbenkian de Ciência, Portugal

Universidade de Lisboa Centro de Estudos Comparatistas, Portugal

Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal

Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2023 - Atual Mass spectrometry & Machine Learning pipeline to tackle Chronic Kidney Disease & Resistant Hypertension: a guide for patient subtyping & precision medicine
FCT 2022.06292.PTDC
Investigador
Fundação para a Ciência e a Tecnologia
Em curso
2021 - Atual Muscle up with intermittent hypoxia: a matter of intensity, gender and metabolism
iNOVA4Health- IUDB/004462/2020/TL2/P2
Investigador responsável
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal

iNOVA4Health, Portugal
iNOVA4Health

Fundação para a Ciência e a Tecnologia
Em curso
2023/09/01 - 2024/09/01 LUMINA - Desenvolvimento de um protótipo "point-of-care" portátil para a análise de urina.
IPL/IDI&CA2023/LUMINA_ISEL
Instituto Politécnico de Lisboa Grupo de Investigação e de Aplicações em Microelectrónica Optoelectrónica e Sensores, Portugal
 Instituto Politécnico de Lisboa
Em curso
2018/10/01 - 2021/09/30 AhR-CYP1A:1 linking environmental exposure and sleep apnea to improve arterial hypertension management
PTDC/MED-TOX/30418/2017
Investigador responsável
Universidade Nova de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018/10/01 - 2021/09/30 Photonic biosensor for point of care and early diagnostics of acute kidney injury
PTDC/NAN-OPT/31311/2017
Investigador
Instituto Politécnico de Lisboa Instituto Superior de Engenharia de Lisboa, Portugal

Universidade Nova de Lisboa UNINOVA Instituto de Desenvolvimento de Novas Tecnologias, Portugal

Universidade Nova de Lisboa, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2016 - 2020 Diagnosis, monitoring and prevention of exposure-related non-communicable diseases (DiMoPEx/CA15129)).
CA15129
Investigador
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
 European Cooperation in Science and Technology
Concluído
2017 - 2019 Efficacy of olive oil and phenolic compounds in reversing hypertension induced by chronic intermittent hypoxia
201707-05-30
iNOVA4Health, Portugal
 iNOVA4Health
Concluído
2016 - 2019 (per)Sulfidomics: benchmarking mechanisms underlying drug toxicity and drug resistance in precision medicine
UID/Multi/04462/2013
iN4H_201601-02-021
Investigador responsável
iNOVA4Health, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2016 - 2019 AhR: a therapeutic target for co-morbidities associated with chronic intermittent hypoxia
PAULIF
Investigador
Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior

Gouvernement francais Ministère de l'Enseignement supérieur de la Recherche et de l'Innovation
Concluído
2016 - 2018 (Clinical Trial) Variability of sulfotransferase 1A1 activity in humans: an approach to improve predictive drug response
2016-001395-29
NCT03182595:
Investigador
Hospital da Luz Lisboa, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Hospital da Luz Lisboa
Em curso
2016 - 2018 Targeting monocytes as angiogenesis promoters in cancer- New application for old drugs
Inova4health 201707-05-35
Investigador responsável
Concluído
2016 - 2017 Kidney tubular lesion in HIV patients
PGG/032/2015
Investigador
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
 Gilead Sciences Lda
Concluído
2013/06/01 - 2016/12/31 From small bioactive molecules to an integrated OMICS approach: Mass Spectrometry tools for mechanistic insights into drug-like and functional properties, toxicity, and stress responses
RECI/QEQ-MED/0330/2012
Investigador
Universidade de Lisboa Centro de Química Estrutural, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Centro Hospitalar de Lisboa Central EPE, Portugal

Hospital Professor Doutor Fernando Fonseca EPE, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2014/03/18 - 2015/09/17 HivKIomics - new insights on tubular injury and nephrotoxicity diagnosis and prediction in HIV-infected patients
EXPL/DTP-FTO/1792/2013
Investigador
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Hospital Professor Doutor Fernando Fonseca EPE, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2014/04/01 - 2015/06/30 Point of care testing of cardiovascular disease markers - detection of homocystein-thiolactone
EXPL/DTP-PIC/1758/2013
Investigador
Egas Moniz Cooperativa de Ensino Superior CRL, Portugal

Centro de Investigação Interdisciplinar Egas Moniz, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2013 - 2015 HIV nefromics: new markers of nephrotoxicity induced by antiretrovirals in hiv+ patients
SPN2013
Investigador
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
 Sociedade Portuguesa de Nefrologia
2012 - 2015 Zebrafish as a biomedical tool to evaluate drug toxicity
FCG121986
Investigador
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
 Fundação Calouste Gulbenkian
Concluído
2013/11/02 - 2014/11/01 TeachIng an olD drug nEw tricks: re-profiling An anti-HIV drug as an HDL modulator
EXPL/DTP-FTO/0204/2012
Investigador responsável
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Universidade de Lisboa Faculdade de Farmácia, Portugal

Centro Hospitalar de Lisboa Central EPE, Portugal

Hospital Professor Doutor Fernando Fonseca EPE, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2011/03/15 - 2014/09/14 Hepatic toxicity in HIV-infected individuals exposed to nevirapine
PTDC/SAU-TOX/111663/2009
Investigador
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Centro Hospitalar de Lisboa Central EPE, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2010 - 2013 Bioactivation routes of the anti - HIV drug Nevirapine: identification of reactive metabolites and mutagenic potential
PTDC/QUI-QUI/113910/2009
Investigador
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2002 - 2004 Implementation of a laboratory for therapeutic drug monitoring of antiretroviral drugs in HIV infected patients
CNLCS2002
Bolseiro de Investigação
Fundação para a Ciência e a Tecnologia
Concluído

Outro

Designação Financiadores
2017 - 2020 AhR-CYP1A: linking environmental exposure and sleep apnea to improve arterial hypertension management
PTDC/MED-TOX/30418/2017
Universidade Nova de Lisboa Medical School, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
Produções

Publicações

Artigo em conferência
  1. Alessandro Fantoni; Miguel Fernandes; J. Fidalgo; Karina Soto; Pereira SA; A. Moreno; C. Domingos; et al. "The LUMINA setup for a light-based urine monitoring and analysis". 2024.
    10.1117/12.3022182
  2. Gracio, Patricia C.; Goncalves-Dias, Clara; Lopes-Coelho, Filipa; Monteiro, Emilia C.; Serpa, Jacinta; da Silva, Claudia L.; Pereira, Sofia A.. "Changes in N-acetyltransferase 8 in kidney tubular cell: injury, recovery and mesenchymal stromal cell-based therapy". 2019.
    10.1109/enbeng.2019.8692517
  3. Gonçalves-Dias, Clara; Campos, P; Diogo, Lucília N.; Trigo, D; Correia, M João; Lemos, AR; Monteiro, Emília C.; Soto, Karina; Pereira, Sofia. "MP312 Kidney disease progression in HIV-infected patients related with the detoxification of endogenous electrophilic species.". Trabalho apresentado em 54th ERA-EDTA Congress, 2017.
  4. Pereira, Sofia; Pereira SA; Pereira, Sofia A.. "Epigenetic Markers of Hepatotoxicity: A Nevirapine Story". Trabalho apresentado em 41st Annual Meeting of Environmental-Mutagen-Society, 2010.
    https://doi.org/10.1002/em.20625
  5. Pereira SA; RM Corte-Real; T Branco; F Lampreia; I Germano; U Caixas; E.C. Monteiro. "Efavirenz plasma concentrations - Is gender important?". 2004.
Artigo em revista
  1. Francesca Polli; Rosaceleste Zumpano; Gianluca Zanellato; Pereira SA; Alessandro Fantoni; Franco Mazzei; M.Gabriela G. Almeida. "Optimization of a gold electrodeposited platform for the development of electrochemical immunosensors". Electrochimica Acta 518 (2025): https://novaresearch.unl.pt/en/publications/28ee2cdd-2b43-49dc-bf46-1b801e8f4e6b.
    10.1016/j.electacta.2025.145787
  2. de Melo Junior, Antonio Ferreira; Escouto, Leonardo; Pimpão, António B.; Peixoto, Pollyana; Brasil, Girlandia; Ronchi, Silas Nascimento; Pereira, Sofia Azeredo; Bissoli, Nazaré Souza. "Anabolic-androgen steroids: A possible independent risk factor to Cardiovascular, Kidney and Metabolic Syndrome". Toxicology and Applied Pharmacology 495 (2025): 117238. https://doi.org/10.1016/j.taap.2025.117238.
    10.1016/j.taap.2025.117238
  3. Catarina Domingos; Alessandro Fantoni; Miguel Fernandes; Jorge Fidalgo; Sofia Azeredo Pereira. "Low-Cost Raman Spectroscopy Setup Combined with a Machine Learning Model". Sensors (2025): https://doi.org/10.3390/s25030659.
    10.3390/s25030659
  4. Inês Guerra Mollet; Ricardo Viana-Soares; Catarina Cardoso-Pires; Nuno L. Soares; João Pedro Marto; Marcelo Mendonça; Cláudia S.F. Queiroga; et al. "Identification of human circulating factors following remote ischemic conditioning (RIC)". Free Radical Biology And Medicine 224 (2024): 23-38. https://novaresearch.unl.pt/en/publications/7bb934a5-d39f-46c4-ae11-299540048947.
    10.1016/j.freeradbiomed.2024.08.017
  5. Fernandes, Joana L.; Martins, Fátima O.; Olea, Elena; Prieto-Lloret, Jesus; Braga, Patrícia C.; Sacramento, Joana F.; Sequeira, Catarina O.; et al. "Chronic Intermittent Hypoxia-Induced Dysmetabolism Is Associated with Hepatic Oxidative Stress, Mitochondrial Dysfunction and Inflammation". Antioxidants 12 11 (2023): 1910. http://dx.doi.org/10.3390/antiox12111910.
    Publicado • 10.3390/antiox12111910
  6. Martins, Ana Rita; Azeredo-Lopes, Sofia; Pereira, Sofia Azeredo; Moreira, Inês; Weigert, André Luíz. "Klotho and lean mass as novel cardiovascular risk factors in hemodialysis patients". Clinical Kidney Journal 16 12 (2023): 2587-2596. http://dx.doi.org/10.1093/ckj/sfad166.
    Publicado • 10.1093/ckj/sfad166
  7. Baltazar, Pedro; de Melo Junior, Antonio Ferreira; Fonseca, Nuno Moreira; Lança, Miguel Brito; Faria, Ana; Sequeira, Catarina O.; Teixeira-Santos, Luísa; et al. "Oxalate (dys)Metabolism: Person-to-Person Variability, Kidney and Cardiometabolic Toxicity". Genes 14 9 (2023): 1719. http://dx.doi.org/10.3390/genes14091719.
    Publicado • 10.3390/genes14091719
  8. Dias-Carvalho, Ana; Margarida-Araújo, Ana; Reis-Mendes, Ana; Sequeira, Catarina Oliveira; Pereira, Sofia Azeredo; Guedes de Pinho, Paula; Carvalho, Félix; et al. "A Clinically Relevant Dosage of Mitoxantrone Disrupts the Glutathione and Lipid Metabolic Pathways of the CD-1 Mice Brain: A Metabolomics Study". International Journal of Molecular Sciences 24 17 (2023): 13126. http://dx.doi.org/10.3390/ijms241713126.
    Publicado • 10.3390/ijms241713126
  9. Zhang, Junmin; Wang, Rong; Pereira, Sofia Azeredo. "Editorial: Drug metabolism and transport: the Frontier of personalized medicine". Frontiers in Pharmacology 14 (2023): http://dx.doi.org/10.3389/fphar.2023.1246827.
    Publicado • 10.3389/fphar.2023.1246827
  10. Pimpão, António; Sousa, Cátia; Correia, M João; Coelho, Nuno; Monteiro, EC; Melo Junior, AF; Pereira, Sofia A.. "Control of Arterial Hypertension by the AhR Blocker CH-223191: A Chronopharmacological Study in Chronic Intermittent Hypoxia Conditions". Advances in Experimental Medicine and Biology 147 (2023):
    Publicado • https://doi.org/10.1007/978-3-031-32371-3_4
  11. Pepe, Bruno; Prazeres, Teresa; Carnevale, Andreia; Calça, Rita; Matias, Patricia; Branco, Patricia; Azeredo-Lopes, Sofia; Pereira, Sofia Azeredo; Martins, Ana Rita. "#3546 “SURPRISE QUESTION”: IS IT A USEFUL TOOL IN CKD STAGES 4 TO 5?". Nephrology Dialysis Transplantation 38 Supplement (2023): http://dx.doi.org/10.1093/ndt/gfad063c_3546.
    Publicado • 10.1093/ndt/gfad063c_3546
  12. Mauricio, Miguel Nuno Petrucci; Merino, Jaime Hernán; Carnevale, Andreia; Pereira, Sofia Azeredo; Martins, Ana Rita; Calça, Rita; Matias, Patricia; et al. "#2674 ASSOCIATION BETWEEN SARCOPENIA, BODY COMPOSITION AND FRAILTY IN PERITONEAL DIALYSIS PATIENTS: A MULTI-CENTRIC STUDY". Nephrology Dialysis Transplantation 38 Supplement (2023): http://dx.doi.org/10.1093/ndt/gfad063b_2674.
    Publicado • 10.1093/ndt/gfad063b_2674
  13. Branco, Patrícia; Calça, Rita; Martins, Ana Rita; Mateus, Catarina; Jervis, Maria João; Gomes, Daniel Pinto; Azeredo-Lopes, Sofia; et al. "Fibrosis of Peritoneal Membrane, Molecular Indicators of Aging and Frailty Unveil Vulnerable Patients in Long-Term Peritoneal Dialysis". International Journal of Molecular Sciences 24 5 (2023): 5020. http://dx.doi.org/10.3390/ijms24055020.
    10.3390/ijms24055020
  14. Branco, Patrícia; Martins, Ana Rita; Calça, Rita; Mateus, Catarina; Jervis, Maria João; Rodrigues, Anabela; Lopes, Sofia Azeredo; et al. "Alpha-klotho and peritoneal membrane status: A hypothesis generating study". European Journal of Clinical Investigation 53 3 (2022): http://dx.doi.org/10.1111/eci.13903.
    10.1111/eci.13903
  15. Lopes-Coelho, Filipa; Martins, Filipa; Hipólito, Ana; Conde, Sílvia V.; Pereira, Sofia A.; Gonçalves, Luís G.; Serpa, Jacinta. "A Metabolic Signature to Monitor Endothelial Cell Differentiation, Activation, and Vascular Organization". Biomedicines 10 9 (2022): 2293. http://dx.doi.org/10.3390/biomedicines10092293.
    10.3390/biomedicines10092293
  16. Filipa Lopes-Coelho; Sofia Nunes; Filipa Martins; Ana Hipolito; Sofia Gouveia-Fernandes; Germana Domingues; Bernardete F. Melo; et al. "Propranolol therapy for cerebral cavernous malformations". World Academy of Sciences Journal 4 3 (2022): https://novaresearch.unl.pt/en/publications/2de56f91-0662-4c59-94ee-de2b4003af30.
    10.3892/wasj.2022.158
  17. Correia, Maria João; Pimpão, António B.; Fernandes, Dalila G. F.; Morello, Judit; Sequeira, Catarina O.; Calado, Joaquim; Antunes, Alexandra M. M.; et al. "Cysteine as a Multifaceted Player in Kidney, the Cysteine-Related Thiolome and Its Implications for Precision Medicine". Molecules 27 4 (2022): 1416. http://dx.doi.org/10.3390/molecules27041416.
    Publicado • 10.3390/molecules27041416
  18. Carecho, Rafael; Figueira, Inês; Terrasso, Ana Paula; Godinho-Pereira, Joana; de Oliveira Sequeira, Catarina; Pereira, Sofia Azeredo; Milenkovic, Dragan; et al. "Circulating (Poly)phenol Metabolites: Neuroprotection in a 3D Cell Model of Parkinson's Disease". Molecular Nutrition & Food Research (2021): 2100959. http://dx.doi.org/10.1002/mnfr.202100959.
    10.1002/mnfr.202100959
  19. Coelho, N. R.; Pimpão, A. B.; Correia, M. J.; Rodrigues, T. C.; Monteiro, E. C.; Morello, J.; Pereira, S. A.. "Pharmacological blockage of the AHR-CYP1A1 axis: a call for in vivo evidence". Journal of Molecular Medicine 100 2 (2021): 215-243. http://dx.doi.org/10.1007/s00109-021-02163-2.
    Publicado • 10.1007/s00109-021-02163-2
  20. Correia, Maria João; Pimpão, António B.; Lopes-Coelho, Filipa; Sequeira, Catarina O.; Coelho, Nuno R.; Gonçalves-Dias, Clara; Barouki, Robert; et al. "Aryl Hydrocarbon Receptor and Cysteine Redox Dynamics Underlie (Mal)adaptive Mechanisms to Chronic Intermittent Hypoxia in Kidney Cortex". Antioxidants 10 9 (2021): 1484. http://dx.doi.org/10.3390/antiox10091484.
    Publicado • 10.3390/antiox10091484
  21. Nunes, Sofia C.; Ramos, Cristiano; Santos, Inês; Mendes, Cindy; Silva, Fernanda; Vicente, João B.; Pereira, Sofia A.; et al. "Cysteine Boosts Fitness Under Hypoxia-Mimicked Conditions in Ovarian Cancer by Metabolic Reprogramming". Frontiers in Cell and Developmental Biology 9 (2021): http://dx.doi.org/10.3389/fcell.2021.722412.
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  87. Dias C; Marinho A; Morello J; Almeida G; Caixas U; Soto K; Monteiro E; et al. "Monitoring of the lactonase activity of paraoxonase-1 enzyme in HIV-1-infection.". Journal of the International AIDS Society 17 (2014): 19682. http://europepmc.org/abstract/med/25397432.
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  88. Marinho A; Dias C; Antunes A; Caixas U; Branco T; Marques M; Monteiro E; Pereira S. "Sex differences in apolipoprotein A1 and nevirapine-induced toxicity.". Journal of the International AIDS Society (2014): http://europepmc.org/abstract/med/25394082.
    10.7448/IAS.17.4.19575
  89. Afonso, Lara P.; Dias, Clara G.; Marinho, Aline T.; Esteves, Adriana; Jacinto, Ana R.; Pintado, Petra; Lopes, Susana S.; et al. "Paraoxonase as part of endogenous free-radical scavenging system in zebrafish (abstract EUROTOX 2014)". Toxicology Letters 229 (2014): S41. https://doi.org/10.1016/j.toxlet.2014.06.185.
    10.1016/j.toxlet.2014.06.185
  90. Dias, Clara G.; Marinho, Aline T.; Caixas, Umbelina; Faustino, Inês; Antunes, Alexandra M.M.; Marques, M. Matilde; Monteiro, Emília C.; Pereira, Sofia A.. "Thiol status in HIV-infected patients: The effect of nevirapine metabolism (abstract EUROTOX 2014)". Toxicology Letters 229 (2014): S95. http://dx.doi.org/10.1016/j.toxlet.2014.06.352.
    10.1016/j.toxlet.2014.06.352
  91. Diogo, Lucilia; Faustino, Inês; Afonso, Ricardo; Pereira, Sofia; Monteiro, Emilia; Santos, Ana. "Oral voluntary ingestion as a stress free alternative to orogastric gavage: The example of losartan chronic administration (abstract EUROTOX 2014)". Toxicology Letters 229 (2014): S166-S167. http://dx.doi.org/10.1016/j.toxlet.2014.06.572.
    10.1016/j.toxlet.2014.06.572
  92. Pinheiro, Pedro F.; Marinho, Aline T.; Antunes, Alexandra M.M.; Marques, M. Matilde; Castro, Matilde F.; Pereira, Sofia A.; Miranda, Joana P.. "Sex differences in hepatic and intestinal contributions for nevirapine biotransformation (abstract EUROTOX 2014)". Toxicology Letters 229 (2014): S240-S241. http://dx.doi.org/10.1016/j.toxlet.2014.06.803.
    10.1016/j.toxlet.2014.06.803
  93. Grilo, Nádia M.; Batalha, Vânia L.; Lopes, Luisa V.; Marques, M. Matilde; Monteiro, Emília C.; Antunes, Alexandra M.M.; Pereira, Sofia A.. "An animal model to explore efavirenz toxicokinetics and its relation to neurological phenotype (abstract EUROTOX 2014)". Toxicology Letters 229 (2014): S244. http://dx.doi.org/10.1016/j.toxlet.2014.06.813.
    10.1016/j.toxlet.2014.06.813
  94. Marinho, Aline T.; Dias, Clara G.; Pinheiro, Pedro F.; Antunes, Alexandra M.M.; Marques, M. Matilde; Monteiro, Emília C.; Miranda, Joana P.; Pereira, Sofia A.. "PON-1 activity as a protective player in nevirapine hepatotoxicity: Data comparison in 2D and 3D cell cultures (abstract EUROTOX 2014)". Toxicology Letters 229 (2014): S134-S135. http://dx.doi.org/10.1016/j.toxlet.2014.06.476.
    10.1016/j.toxlet.2014.06.476
  95. Grilo, Nádia M.; Charneira, Catarina; Pereira, Sofia A.; Monteiro, Emília C.; Marques, M. Matilde; Antunes, Alexandra M.M.. "Bioactivation to an aldehyde metabolite—Possible role in the onset of toxicity induced by the anti-HIV drug abacavir". Toxicology Letters 224 3 (2014): 416-423. http://dx.doi.org/10.1016/j.toxlet.2013.10.036.
    10.1016/j.toxlet.2013.10.036
  96. Marinho, Aline T.; Godinho, Ana L. A.; Novais, David A.; Antunes, Alexandra M. M.; Marques, M. Matilde; Ramos, Teresa; Dias, Clara G.; Monteiro, Emília C.; Pereira, Sofia A.. "Development and validation of an HPLC-UV method for quantifying nevirapine and its main phase I metabolites in human blood". Analytical Methods 6 5 (2014): 1575. http://dx.doi.org/10.1039/c3ay41911h.
    10.1039/c3ay41911h
  97. Dias, Clara G.; Batuca, Joana R.; Marinho, Aline T.; Caixas, Umbelina; Monteiro, Emília C.; Antunes, Alexandra M. M.; Pereira, Sofia A.. "Quantification of the arylesterase activity of paraoxonase-1 in human blood". Anal. Methods 6 1 (2014): 289-294. http://dx.doi.org/10.1039/c3ay41527a.
    10.1039/c3ay41527a
  98. Pereira, Sofia A.. "An animal model to explore efavirenz toxicokinetics and its relation to neurological phenotype". Toxicology Letters (2014): https://publons.com/publon/11121372/.
    10.1016/J.TOXLET.2014.06.813
  99. Pereira, Sofia A.. "Oral voluntary ingestion as a stress free alternative to orogastric gavage: The example of losartan chronic administration". Toxicology Letters (2014): https://publons.com/publon/20372513/.
    10.1016/J.TOXLET.2014.06.572
  100. Dias, Clara G.; Marinho, Aline T.; Caixas, Umbelina; Faustino, Ines; Antunes, Alexandra M. M.; Matilde Marques, M.; Monteiro, Emilia C.; Pereira, Sofia A.. "Thiol status in HIV-infected patients: The effect of nevirapine metabolism". Toxicology Letters (2014): https://publons.com/publon/11121375/.
    10.1016/J.TOXLET.2014.06.352
  101. Marinho, Aline T.; Dias, Clara G.; Pinheiro, Pedro F.; Antunes, Alexandra M. M.; Matilde Marques, M.; Monteiro, Emilia C.; Miranda, Joana P.; Pereira, Sofia A.. "PON-1 activity as a protective player in nevirapine hepatotoxicity: Data comparison in 2D and 3D cell cultures". Toxicology Letters (2014): https://publons.com/publon/5063325/.
    10.1016/J.TOXLET.2014.06.476
  102. Marinho, Aline T.; Godinho, Ana L. A.; Novais, David A.; Antunes, Alexandra M. M.; Matilde Marques, M.; Ramos, Teresa; Dias, Clara G.; Monteiro, Emilia C.; Pereira, Sofia A.. "Development and validation of an HPLC-UV method for quantifying nevirapine and its main phase I metabolites in human blood". Analytical Methods (2014): https://publons.com/publon/4396366/.
    10.1039/C3AY41911H
  103. Pinheiro, Pedro F.; Marinho, Aline T.; Antunes, Alexandra M. M.; Matilde Marques, M.; Castro, Matilde F.; Pereira, Sofia A.; Miranda, Joana P.. "Sex differences in hepatic and intestinal contributions for nevirapine biotransformation". Toxicology Letters (2014): https://publons.com/publon/5063382/.
    10.1016/J.TOXLET.2014.06.803
  104. Dias, Clara G.; Batuca, Joana R.; Marinho, Aline T.; Caixas, Umbelina; Monteiro, Emilia C.; Antunes, Alexandra M. M.; Pereira, Sofia A.. "Quantification of the arylesterase activity of paraoxonase-1 in human blood". Analytical Methods (2014): https://publons.com/publon/4396365/.
    10.1039/C3AY41527A
  105. Harjivan, Shrika G.; Charneira, Catarina; Pereira, Sofia A.; Espadas, Guadalupe; Sabido, Eduard; Beland, Frederick A.; Matilde Marques, M.; Antunes, Alexandra M. M.; Pereira SA. "Covalent histone modification by nevirapine: Potential association with non-AIDS defining cancers". Abstracts of Papers of the American Chemical Society (2014): https://publons.com/publon/10388528/.
  106. Afonso, Lara P.; Dias, Clara G.; Marinho, Aline T.; Esteves, Adriana; Jacinto, Ana R.; Pintado, Petra; Lopes, Susana S.; et al. "Paraoxonase as part of endogenous free-radical scavenging system in zebrafish". Toxicology Letters (2014): https://publons.com/publon/13118814/.
    10.1016/J.TOXLET.2014.06.185
  107. Wanke, Riccardo; Harjivan, Shrika G.; Pereira, Sofia A.; Marques, M. Matilde; Antunes, Alexandra M.M.. "The role of competitive binding to human serum albumin on efavirenz–warfarin interaction: a nuclear magnetic resonance study". International Journal of Antimicrobial Agents 42 5 (2013): 443-446. http://dx.doi.org/10.1016/j.ijantimicag.2013.06.023.
    10.1016/j.ijantimicag.2013.06.023
  108. Marinho, A. T.; Rodrigues, P. M.; Caixas, U.; Antunes, A. M. M.; Branco, T.; Harjivan, S. G.; Marques, M. M.; Monteiro, E. C.; Pereira, S. A.. "Differences in nevirapine biotransformation as a factor for its sex-dependent dimorphic profile of adverse drug reactions". Journal of Antimicrobial Chemotherapy 69 2 (2013): 476-482. http://dx.doi.org/10.1093/jac/dkt359.
    10.1093/jac/dkt359
  109. Miranda, J.P.; Pinheiro, P.F.; Marinho, A.T.; Harjivan, S.G.; Castro, M.; Pereira, S.A.; Antunes, A.M.M.; Marques, M.M.. "3D hepatocyte cultures: A useful tool in the study of Nevirapine bioactivation and toxicity (abstract EUROTOX 2013)". Toxicology Letters 221 (2013): S174. http://dx.doi.org/10.1016/j.toxlet.2013.05.384.
    10.1016/j.toxlet.2013.05.384
  110. Grilo, Nádia M.; Antunes, Alexandra M.M.; Caixas, Umbelina; Marinho, Aline T.; Charneira, Catarina; Conceição Oliveira, M.; Monteiro, Emília C.; Matilde Marques, M.; Pereira, Sofia A.. "Monitoring abacavir bioactivation in humans: Screening for an aldehyde metabolite". Toxicology Letters 219 1 (2013): 59-64. http://dx.doi.org/10.1016/j.toxlet.2013.02.021.
    10.1016/j.toxlet.2013.02.021
  111. Kromdijk, W.; Pereira, S.A.; Rosing, H.; Mulder, J.W.; Beijnen, J.H.; Huitema, A.D.R.. "Development and validation of an assay for the simultaneous determination of zidovudine, abacavir, emtricitabine, lamivudine, tenofovir and ribavirin in human plasma using liquid chromatography–tandem mass spectrometry". Journal of Chromatography B 919-920 (2013): 43-51. http://dx.doi.org/10.1016/j.jchromb.2013.01.005.
    10.1016/j.jchromb.2013.01.005
  112. Miranda, J. P.; Pinheiro, P. F.; Marinho, A. T.; Harjivan, S. G.; Castro, M.; Pereira, S. A.; Antunes, A. M. M.; Marques, M. M.. "3D hepatocyte cultures: A useful tool in the study of Nevirapine bioactivation and toxicity". Toxicology Letters (2013): https://publons.com/publon/5063334/.
    10.1016/J.TOXLET.2013.05.384
  113. Marinho, A. T.; Antunes, A. M. M.; Caixas, U.; Branco, T.; Godinho, A. L. A.; Oliveira, M. C.; Marques, M. M.; et al. "Haptenation of the antiretroviral drug nevirapine upon bioactivation in man". PROCEEDINGS OF THE 6TH EUROPEAN CONGRESS OF PHARMACOLOGY (2013): 155-158. https://publons.com/publon/11121354/.
    10.1016/j.tox.2012.06.013
  114. Charneira, Catarina; Pereira, Sofia A.; Antunes, Alexandra M. M.; Matilde Marques, M.; Catarina Charneira; Pereira SA; Alexandra M. M. Antunes; M. Matilde Marques. "Estrogen-induced systemic lupus erythematosus: Understanding the role of protein adducts in autoimmunity". Abstracts of Papers of the American Chemical Society (2013): https://publons.com/publon/11121338/.
  115. Caixas, Umbelina; Antunes, Alexandra M.M.; Marinho, Aline T.; Godinho, Ana L.A.; Grilo, Nádia M.; Marques, M. Matilde; Oliveira, M. Conceição; et al. "Evidence for nevirapine bioactivation in man: Searching for the first step in the mechanism of nevirapine toxicity". Toxicology 301 1-3 (2012): 33-39. http://dx.doi.org/10.1016/j.tox.2012.06.013.
    10.1016/j.tox.2012.06.013
  116. Charneira, C; Grilo, NM; Pereira, SA; Godinho, ALA; Monteiro, EC; Marques, MM; Antunes, AMM. "N-terminal valine adduct from the anti-HIV drug abacavir in rat haemoglobin as evidence for abacavir metabolism to a reactive aldehydein vivo". British Journal of Pharmacology 167 6 (2012): 1353-1361. http://dx.doi.org/10.1111/j.1476-5381.2012.02079.x.
    10.1111/j.1476-5381.2012.02079.x
  117. Caixas, U.; Ferreira, J.; Marinho, A. T.; Faustino, I.; Grilo, N. M.; Lampreia, F.; Germano, I.; Monteiro, E. C.; Pereira, S. A.. "Long-term maraviroc use as salvage therapy in HIV-2 infection". Journal of Antimicrobial Chemotherapy 67 10 (2012): 2538-2539. http://dx.doi.org/10.1093/jac/dks240.
    10.1093/jac/dks240
  118. Grilo, Nadia M.; Antunes, Alexandra M. M.; Caixas, Umbelina; Gouveia, Sandra; Conceicao Oliveira, M.; Marinho, Aline T.; Monteiro, Emilia C.; Matilde Marques, M.; Pereira, Sofia A.. "Hemoglobin adducts from the antiretroviral abacavir in HIV-infected patients as evidence of bioactivation". Abstracts of Papers of the American Chemical Society (2012): https://publons.com/publon/11121320/.
  119. Charneira, Catarina; Godinho, Ana L. A.; Oliveira, M. Conceição; Pereira, Sofia A.; Monteiro, Emília C.; Marques, M. Matilde; Antunes, Alexandra M. M.. "Reactive Aldehyde Metabolites from the Anti-HIV Drug Abacavir: Amino Acid Adducts as Possible Factors in Abacavir Toxicity". Chemical Research in Toxicology 24 12 (2011): 2129-2141. http://dx.doi.org/10.1021/tx200337b.
    10.1021/tx200337b
  120. Antunes, Alexandra M. M.; Godinho, Ana L. A.; Pereira, Sofia A.; Surratt, Gordon; da Costa, Goncalo Gamboa; Beland, Frederick A.; Matilde Marques, M.. "Nevirapine metabolism to 4-formyl-nevirapine: Possible role in nevirapine toxicity". Abstracts of Papers of the American Chemical Society (2011): https://publons.com/publon/11121358/.
  121. Pereira, S. A.; Batuca, J. R.; Caixas, U.; Branco, T.; Delgado-Alves, J.; Germano, I.; Lampreia, F.; Monteiro, E. C.. "Effect of efavirenz on high-density lipoprotein antioxidant properties in HIV-infected patients". British Journal of Clinical Pharmacology 68 6 (2009): 891-897. http://dx.doi.org/10.1111/j.1365-2125.2009.03535.x.
    10.1111/j.1365-2125.2009.03535.x
  122. Pereira, Sofia A.; Caixas, Umbelina; Branco, Teresa; Germano, Isabel; Lampreia, Fátima; Papoila, Ana L.; Monteiro, Emília C.. "Efavirenz concentrations in HIV-infected patients with and without viral hepatitis". British Journal of Clinical Pharmacology 66 4 (2008): 551-555. http://dx.doi.org/10.1111/j.1365-2125.2008.03238.x.
    10.1111/j.1365-2125.2008.03238.x
  123. Pereira SA; Teresa Branco; Umbelina Caixas; Rita M. Corte-Real; Isabel Germano; Fátima Lampreia; E.C. Monteiro; et al. "Intra-individual variability in efavirenz plasma concentrations supports therapeutic, drug monitoring based on quarterly sampling in the first year of therapy". Therapeutic Drug Monitoring 30 1 (2008): 60-66. https://novaresearch.unl.pt/en/publications/8b1a93ad-17ae-4f01-9fd0-fdf9f8ea0599.
    10.1097/FTD.0b013e318160ce76
  124. Pereira, SA; Batuca, J; Caixas, U; Branco, T; Germano, I; Lampreia, F; Delgado-Alves, J; Monteiro, EC. "HIV and antioxidant lipoprotein-associated effect. Is there a correlation?". Journal of the International AIDS Society 11 Suppl 1 (2008): P96-P96. http://dx.doi.org/10.1186/1758-2652-11-S1-P96.
    10.1186/1758-2652-11-s1-p96
  125. Carneiro, Fernando F.; Oliveira, Mara Lúcia C.; Netto, Guilherme F.; Galvão, Luis A.C.; Cancio, Jacira A.; Bonini, Estela M.; Corvalan, Carlos F.. "Meeting Report: Development of Environmental Health Indicators in Brazil and Other Countries in the Americas". Environmental Health Perspectives 114 9 (2006): 1407-1408. http://dx.doi.org/10.1289/ehp.8486.
    10.1289/ehp.8486
  126. Pereira, Sofia A.; Branco, Teresa; Corte-Real, Rita M.; Germano, Isabel; Lampreia, Fatima; Caixas, Umbelina; Monteiro, Emilia C.. "Long-term and concentration-dependent beneficial effect of efavirenz on HDL-cholesterol in HIV-infected patients". British Journal of Clinical Pharmacology 61 5 (2006): 601-604. http://dx.doi.org/10.1111/j.1365-2125.2006.02619.x.
    10.1111/j.1365-2125.2006.02619.x
  127. Pereira, S. A.; Corte-Real, R. M.; Branco, T.; Germano, I.; Lampreia, F.; Caixas, U.; Monteiro, E. C.. "Target plasma concentration for efavirenz in HIV-infected patients". Fundamental & Clinical Pharmacology (2004): https://publons.com/publon/28485541/.
Artigo em revista (magazine)
  1. Pereira, Sofia A.; Pereira, Sofia. "Estudos de iniciativa do investigador nas estratégias de otimização terapêutica.", Revista "O Hospital", 2017, https://issuu.com/apdhpublicacoes/docs/revista-hospital-x.
Capítulo de livro
  1. Clara Gonçalves-Dias; Catarina O. Sequeira; João Vicente; M. João Correia; Nuno R. Coelho; Judit Morello; AMM Antunes; et al. "A Mechanistic-Based and Non-invasive Approach to Quantify the Capability of Kidney to Detoxify Cysteine-Disulfides". 109-120. Springer, 2021.
    10.1007/978-3-030-63908-2_8
  2. João Filipe Raposo; José A. Belo; Sílvia V. Conde; Monteiro, EC; José Silva Nunes; Pereira, Sofia A.; Gabriela A. Silva; Maria Paula Macedo. "B From a classical to a new nova perspective on cardiometabolic diseases". In From Life Molecules to Global Health, 261-290. PRINCIPIA, 2021.
    Publicado
  3. Clara Gonçalves-Dias; Catarina O. Sequeira; João B. Vicente; Maria João Correia; Coelho, NR; Morello, Judit; Antunes, Alexandra; et al. "A Mechanistic-Based and Non-Invasive Approach to Quantify the Capability of Kidney to Detoxify Cysteine-Disulfide". In Urinomics. Springer International Publishing AG, 2020.
    No prelo
  4. Coelho, Nuno R.; Dias, Clara G.; João Correia, M.; Grácio, Patrícia; Serpa, Jacinta; Monteiro, Emília C.; Diogo, Lucília N.; Pereira, Sofia A.. "Cysteine Oxidative Dynamics Underlies Hypertension and Kidney Dysfunction Induced by Chronic Intermittent Hypoxia". In Advances in Experimental Medicine and Biology, 83-88. Springer International Publishing, 2018.
    10.1007/978-3-319-91137-3_10
  5. Pereira, Sofia A.; Wanke, Riccardo; Marques, M. Matilde; Monteiro, Emília C.; Antunes, Alexandra M.M.; Pereira, S.A.; Wanke, R.; et al. "Insights into the Role of Bioactivation Mechanisms in the Toxic Events Elicited by Non-nucleoside Reverse Transcriptase Inhibitors". In Advances in Molecular Toxicology Volume 6, 1-39. Elsevier, 2012.
    10.1016/b978-0-444-59389-4.00001-x
  6. Pereira, Sofia A.. "HDL in HIV infection: the effect of the antiretroviral efavirenz on HDL-quality and quantity.". In Advances in medicine and biology. Nova Science Publishers, Inc, 2012.
    Publicado
  7. "Understanding the Molecular Basis for the Hazards Associated with Nevirapine Treatment, in: L.V". In Advances in Medicine and Biology. NovaPublishers, 2012.
    Publicado
Poster em conferência
  1. Teixeira-Santos, Luísa; Sousa, Cátia; Birne, Rita; Silva Sousa, Henrique; Branco, Patrícia; Monteiro, Emilia C.; Pereira, Sofia A.. "“Nephrologists’ Perspectives On Aligning Pharmacokinetics Academic Education With Clinical Practice”". Trabalho apresentado em Encontro Renal 2024 - XXXVIII Congresso Português de Nefrologia, 2024.
  2. António B. Pimpão; Correia, M João; Mecha, Elsa; Sequeira O. C.; FERNANDES, DALILA; Ana Teresa Serra; Silva, Sandra; et al. Autor correspondente: Pereira, Sofia. "OHTyr Mitigates CIH-induced Hypertension: AhR Signaling and Cysteine Pathways". Trabalho apresentado em European Respiratory Society (ERS) Research Seminar - Sleep apnoea and its consequences: from animal models to precision medicine, 2024.
  3. Figueira, Inês; Carecho, Rafael; Terrasso, Ana Paula; Godinho-Pereira, Joana; de Oliveira Sequeira, Catarina; Pereira, Sofia A.; Milenkovic, Dragan; et al. "Low-molecular-weight (poly)phenol metabolites preconditioning attenuates dopaminergic degeneration in a 3D cellular model of Parkinson's disease". Trabalho apresentado em 3rd International Conference on Food Bioactives and Health (FBHC), 2022.
  4. Carecho, Rafael; Figueira, Inês; Terrasso, Ana Paula; Godinho-Pereira, Joana; de Oliveira Sequeira, Catarina; Pereira, Sofia A.; Milenkovic, Dragan; et al. "Neuroprotective effects of circulating (poly)phenol metabolites in MPP(+)-stimulated dopaminergic neurons". Trabalho apresentado em 10th International Conference on Polyphenols and Health (ICPH2022), 2022.
  5. Carecho, Rafael; Figueira, Inês; Terrasso, Ana Paula; Godinho-Pereira, Joana; de Oliveira Sequeira, Catarina; Pereira, Sofia A.; Milenkovic, Dragan; et al. "Low-molecular weight (poly)phenol metabolites found in circulation trigger pre-conditioning mechanisms protecting a 3D cell model of Parkinson's disease from an oxidative insult". Trabalho apresentado em International Conference on Alzheimer¿s and Parkinson¿s Diseases and related neurological disorders (AD/PD 2022), 2022.
  6. Monteiro, EC; Coelho, Nuno; Tomkiewcz, Céline; Correia, M João; Pimpão, António; Barouki, Robert; Coumoul, Xavier; Pereira, Sofia A.. "P19-ARYL HYDROCARBON RECEPTOR ANTAGONISTS - A NEW ENTRY IN ANTIHYPERTENSIVE ARMAMENTARIUM OF OBSTRUCTIVE SLEEP APNEA?". Trabalho apresentado em ESH-ISH Joint Meeting - Hypertension meeting participation, 2021.
  7. Marto, Natália; Morello, Judit; Antunes, AMM; Monteiro, EC; Pereira, Sofia A.. "Phenotyping SULT in Man: a Simple Metric Using Paracetamol as Probe". Trabalho apresentado em ASPET Annual Meeting at EB 2021, 2021.
  8. Correia, M João; Coelho, Nuno; Elsa Mecha; Sandra Silva; Bronze, Maria; Monteiro, EC; Pereira, Sofia A.. "Olive oil and arterial hypertension (htn): a focus on hydroxytyrosol". Trabalho apresentado em II Conference NOVASaude Nutrition, 2021.
  9. Branco, Patrícia; Martins, Ana Rita Mateus; Coelho, Rita Alexandre; Pinto, Daniel G; Mateus, Catarina; Calça, Rita; Sequeira CO; Morello, Judit; Pereira, Sofia A.. "A Pilot Evaluation of Thiol Metabolome in Peritoneal Dialysate as an Indicator of Peritoneal Fibrosis (PO1247)". Trabalho apresentado em Kidney Week 2020, 2020.
  10. Fernandes D.G.H.; Coelho N.R.; Correia, M João; Tomé C.S.; Sequeira CO; Monteiro, EC; Matias P.M.; Pereira, Sofia A.; Vicente, João B.. "The six W´s of protein cysteinylation in the kidney.". Trabalho apresentado em 10th ITQB NOVA PhD Students Meeting, 2020.
  11. Sequeira CO; Caixas, Umbelina; Pereira, Sofia A.; Maravilha, C.; Casella, I.; Soto, K.; Branco, T.; et al. "Anti-Mullerian hormone a plausible indicator of cardiometabolic risk in HIV-infected women (PE10/6)". Trabalho apresentado em EACS 2019, 2019.
  12. Cipriano, Madalena; Pinheiro, Pedro F.; Sequeira, Catarina; Santos, Jorge M.; Oliveira, Nuno G.; Rodrigues, Joana S; Antunes, Alexandra M.; et al. "The integrated assessment of nevirapine biotransformation unveils the biocompetence of a 3D in vitro model of human hepatocyte-like cells for liver function studies". Trabalho apresentado em 11th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, 2019.
    10.3389/978-2-88945-675-8
  13. Marinho, Aline T.; Batuca, Joana R.; Miranda, Joana P; Caixas, Umbelina; Branco, Teresa; Soto, Karina; Bourbon, M; et al. "The potential of Nevirapine metabolites to treat HDL dysfunction-related diseases". Trabalho apresentado em International Atherosclerosis Society - HDL workshop 2019: structure, novel functions and therapeutic applications, 2019.
  14. Judit Morello; Sara M. Teixeira; Joao Rodrigues; Sara Maia; Atlas Sardoo; Rita Pinheiro Torres; Pereira SA; et al. "Diagnosis of Inflammatory Rheumatic Diseases: Preliminary Approach by Urine Metabolomics". Trabalho apresentado em Annual Meeting of the American College of Rheumatology, 2019.
  15. Gonçalves-Dias, Clara; Soto, K; Sancho-Martinez, SM; Correia, M João; Coelho, Nuno; Prieto-Vicente, M; Monteiro, EC; López-Hernández, FJ; Pereira, Sofia A.. "Changes in mercapturates of cysteinedisulfides associate to acute kidney injury induced by cisplatin and gentamicin". Trabalho apresentado em ISN World Congress of Nephrology 2019, 2019.
  16. José Pedro Costa; Caixas, Umbelina; Sequeira CO; Morello, Judit; Sofia Azeredo-Lopes; Cláudia Á.F. Nunes; Teresa Branco; et al. "Urinary kynurenine-to-tryptophan ratio is not related to sex-hormones signature in HIV-infected woman at menopausal transition age". Trabalho apresentado em iMEDConference 11, 2019.
  17. Pereira, Sofia. "Blockade of AhR reverts systemic hypertension induced by chronic intermittent hypoxia in rats". Trabalho apresentado em AhR Meeting, Paris, France, 2018.
  18. Pereira, Sofia. "Renal cysteine-disulfide stress is a common feature of cardiometabolic diseases". Trabalho apresentado em I NoTeS Congress – Novel Therapeutic Strategies for Noncommunicable Diseases, Porto, Portugal, 2018.
  19. Pereira, Sofia. "Mercapturates of cysteine-S-disulfides in kidney dysfunction in HIV-infection". Trabalho apresentado em 1st Workshop on Human Biomonitoring in Portugal (1st HBM-PT), Lisbon, Portugal, 2018.
  20. Pereira, Sofia. "Mercapturates of cysteine-S-disulfides for risk assessment of exposure-related hypertension and kidney dysfunction". Trabalho apresentado em DiMoPEx Working Groups Meeting, 2nd International conference on Pollution in living and working environments and health, Bentivoglio, Italy, 2017.
    https://www.journalhealthpollution.org/doi/pdf/10.5696/2156-9614.8.17.1
  21. Pereira, Sofia. "Mercapturate pathway and kidney disease progression in HIV-patients: a 1-year prospective study". Trabalho apresentado em ISN World Congress of Nephrology 2017, México., 2017.
  22. Nádia Grilo; Maria Correia; Catarina Sequeira; Shrika G Harjivan; Umbelina Caixas; Lucilia Diogo; M Matilde Marques; et al. "Monitoring of 8-hydroxy-efavirenz concentrations for management of mood changes". Trabalho apresentado em International Congress of Drug Therapy in HIV Infection, Glasgow, 2016.
    http://dx.doi.org/10.7448/IAS.19.8.21487
  23. Pereira, Sofia. "S-protein thiol-omics to assess the redox-modulation effects of antiretroviral drugs". Trabalho apresentado em International Congress of Drug Therapy in HIV Infection, Glasgow, 2016.
    10.7448/IAS.19.8.21487
  24. Lemos, Ana Rita; Dias, Clara G.; Coelho, Nuno R.; Casimiro, Nelson F; Bourbon, Mafalda; Pereira, Sofia A.. "Molecular targeting of proteins by homocysteine: implications in familial and clinical hypercholesterolemia.". Trabalho apresentado em iMed 7.0 Conference, 2015.
  25. Soto, Karina; Dias, CG; Campos, P; Lemos, Ana R.; Marinho, Aline T.; Papoila, AL; Pereira, Sofia A.. "Paraoxonase-1 in early kidney dysfunction in HIV+ patients under protease inhibitors". Trabalho apresentado em ISN World Congress of Nephrology, 2015.
Recurso online
  1. Pereira, Sofia. Zebrafish is an attractive model to anticipate drug-induced renal injury in humans.. 2018. https://atlasofscience.org/zebrafish-is-an-attractive-model-to-anticipate-drug-induced-renal-injury-in-humans/.
Resumo em conferência
  1. M. João Correia; António B. Pimpão; Elsa Mecha; M Rita Ventura; Beatriz Martins; Teresa Serra; Sousa, Cátia; et al. "A METABOLOMIC APPROACH REVEALS THAT HYDROXYTYROSOL IMPACTS TRYPTOPHAN METABOLISM IN A RAT MODEL OF HYPERTENSION ASSOCIATED TO OBSTRUTIVE SLEEP APNEA". Trabalho apresentado em 53rd Meeting of the Portuguese Society of Pharmacology, Coimbra, 2023.
  2. Pereira, Sofia. "The antihypertensive effect of ahr antagonist is related to circadian variation of blood pressure in chronic intermittent hypoxia condition [oral presentation]". Trabalho apresentado em L Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXVIII Reunião de Farmacologia Clínica/ XIX Reunião de Toxicologia, Coimbra, 2020.
  3. Pereira, Sofia. "Hydroxytyrol prevents increase in systolic blood pressure induced by chronic intermittent hypoxia [oral presentation]". Trabalho apresentado em XLIX Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXVII Reunião de Farmacologia Clínica/ XVIII Reunião de Toxicologia, Porto, 2019.
  4. Pereira, Sofia. "Pharmacological blocking of AhR reduces hypertension induced by chronic intermittent hypoxia [oral presentation]". Trabalho apresentado em XLIX Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXVII Reunião de Farmacologia Clínica/ XVIII Reunião de Toxicologia, Porto, 2019.
  5. Pereira, Sofia. "Urinary mercapturates of cysteine-disulfides decrease in models of drug-induced acute kidney injury [oral presentation]". Trabalho apresentado em XLIX Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXVII Reunião de Farmacologia Clínica/ XVIII Reunião de Toxicologia, Porto, 2019.
  6. Morello, Judit; M. Teixeira, Sara; Rodrigues, João; Maia, Sara; Mashayekhi Sardoo, Atlas; Pinheiro Torres, Rita; Pereira, Sofia; et al. "Diagnosis of Inammatory Rheumatic Diseases: Preliminary Approach by Urine Metabolomics". Trabalho apresentado em 2019 ACR/ARP Annual Meeting, 2019.
  7. Pereira, Sofia. "Metabolomics of drug-induced renal injury in zebrafish larvae. [oral presentation]". Trabalho apresentado em XLVII meeting of thePortuguese Society of Pharmacology, 2018.
  8. Pereira, Sofia. "Enzymes involved in cysteine metabolism underlie hypoxia adaptation in ovarian cancer [oral presentation]". Trabalho apresentado em 8th International conference on Tumor Microenvironment, 2018.
    10.1007/s12307-018-0212-6
  9. Pereira, Sofia. "Mercapturatos de dissulfetos de cisteína como marcadores de progressão de doença renal: comparação entre dois modelos animais de pré-diabetes [oral presentation]". Trabalho apresentado em 14º Congresso Português de Diabetes (Rev Port Diab 2018, 13(1) Suppl:37-40), 2018.
  10. Pereira, Sofia. "AhR: linking environmental exposure and sleep apnea to improve arterial hypertension management [oral presentation]". Trabalho apresentado em I NoTeS Congress – Novel Therapeutic Strategies for Noncommunicable Diseases, Porto, 2018.
  11. Pereira, Sofia. "Cysteine disulfide stress is a common mechanism in kidney injury associated to metabolic inflammation models [oral communication]". Trabalho apresentado em XXXI Congresso Português de Nefrologia, Vilamoura, 2018.
  12. Pereira, Sofia. "Cysteine oxidative dynamics underlies hypertension and kidney dysfunction induced by chronic intermittent hypoxia [oral presentation]". Trabalho apresentado em XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXVI Reunião de Farmacologia Clínica/ XVII Reunião de Toxicologia, Lisbon, 2018.
  13. Pereira, Sofia. "AhR metabolic pathway in hypertension induced by chronic intermittent hypoxia [oral presentation]". Trabalho apresentado em XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXVI Reunião de Farmacologia Clínica/ XVII Reunião de Toxicologia, Lisbon, 2018.
  14. Pereira, Sofia. "Effect of chronic intermittent hypoxia in the temporal variation of mercapturates of cysteineS-disulfides [oral presentation]". Trabalho apresentado em XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXVI Reunião de Farmacologia Clínica/ XVII Reunião de Toxicologia, Lisbon, 2018.
  15. Pereira, Sofia. "Is zebrafish a good model to assess drug-induced renalinjury? [inivited oral presentation]". Trabalho apresentado em 3rd InternationalConference on Urine Omics and 2nd International Caparica Conference inTranslational Nephrology, 2017.
  16. Pereira, Sofia. "Comparison of a marker of kidney disease progression between two animal models of pre-diabetes [oral presentation]". Trabalho apresentado em Renal disease in obesity and diabetes. Advances in pathogenesis and therapeutics – Diabesity Working Group, Lisbon, 2017.
  17. Pereira, Sofia. "Cysteine oxidation in kidney: the effect of short and long-term exposure to chronic intermittent hypoxia [1 minute elevator talk]". Trabalho apresentado em EMBO Workshop: Thiol oxidation in toxicity and signaling, Sant Feliu de Guïxols, 2017.
  18. Pereira, Sofia. "Cysteine oxidation in the underlying mechanisms of kidney fibrosis induced by chronic intermittent hypoxia [oral presentation]". Trabalho apresentado em XXth Meeting of the International Society of Arterial Chemoreception (ISAC), Baltimore, 2017.
  19. Pereira, Sofia. "S-thiolated protein profile is influenced by efavirenz [oral presentation]". Trabalho apresentado em XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXV Reunião de Farmacologia Clínica/ XVI Reunião de Toxicologia, Coimbra, 2017.
  20. Pereira, Sofia. "Temporal and tissue dependent effects of Efavirenz exposure: implications for its neurotoxicity [oral presentation]". Trabalho apresentado em XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXV Reunião de Farmacologia Clínica/ XVI Reunião de Toxicologia, Coimbra, 2017.
  21. Pereira, Sofia. "uNAC as a novel marker of kidney disease progression in HIV-patients [oral presenation]". Trabalho apresentado em XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXV Reunião de Farmacologia Clínica/ XVI Reunião de Toxicologia, Coimbra, 2017.
  22. Pereira, Sofia. "Kidney cysteine redox cycle in rats exposed to chronic intermittent hypoxia [oral presentation]". Trabalho apresentado em XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXV Reunião de Farmacologia Clínica/ XVI Reunião de Toxicologia, Coimbra, 2017.
  23. Pereira, Sofia. "Molecular targeting of proteins by homocysteine in hypercholesterolemia [oral presentation]". Trabalho apresentado em . XLVI Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXIII Reunião de Farmacologia Clínica/ XV Reunião de Toxicologia, 2016.
  24. Pereira, Sofia. "Modulation of paraoxonase-1 by nevirapine: comparison between three in vitro models [oral presentation]". Trabalho apresentado em XLVI Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXIII Reunião de Farmacologia Clínica/ XV Reunião de Toxicologia, 2016.
  25. Pereira, Sofia. "Urinary N-acetylated cysteine-disulfides as indicators of kidney disease progression in HIV-infected patients [oral presentation]". Trabalho apresentado em 7th European Congress of Pharmacology (EPHAR), 2016.
  26. Pereira, Sofia. "Efavirenz biotransformation at the onset of mood changes in HIV-infected male patients [oral presentation]". Trabalho apresentado em XLVI Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXIV Reunião de Farmacologia Clínica/ XV Reunião de Toxicologia, Porto, 2016.
  27. Dias, Clara G.; Diogo, Lucília N.; Campos, Pedro; Lemos, Ana R.; Monteiro, Emília C.; Soto, Karina; Pereira, Sofia A.. "Urinary N-acetyl cysteine-disulfides and kidney disease progression in HIV-infected patients: a prospective study (Abstract)". 2016.
    Publicado
  28. Pereira, Sofia. "Monitoring glomerular function in zebrafish larvae (Danio rerio) exposed to nephrotoxic drugs. [oral presentation]". Trabalho apresentado em XLV meeting of the Portuguese Society of Pharmacology, 2015.
  29. Dias, Clara G.; Casimiro, Nelson; Coelho, Nuno; Lemos, Ana R.; Monteiro, Emília C.; Soto, Karina; Pereira, Sofia A.. "Serum non-protein bound homocysteine levels are related with chronic kidney disease progression in HIV-infected patients". 2015.
    Publicado
  30. Pereira, Sofia. "The role of Nevirapine phase I metabolites in the renal function of HIV-infected patients [oral presentation]". Trabalho apresentado em 1st International Caparica Conference in Translational Nephrology & 18th Portuguese Symposium on Renal Diseases, 2014.
  31. Pereira, Sofia. "Antivíricos diretos e imunossupressores: interações [invited oral presentation]". Trabalho apresentado em Workshop Hepatite C - Inovação Farmacologia e Transplantação, 2014.
  32. Pereira, Sofia A.. "Thiol status in HIV-infected patients: the effect of nevirapine metabolism.". 2014.
    DOI: 10.1016/j.toxlet.2014.06.352
  33. Pereira, Sofia A.. "PON-1 activity as a protective player in nevirapine hepatotoxicity: data comparison in 2D and 3D cell cultures.". 2014.
    DOI: 10.1016/j.toxlet.2014.06.476
  34. Pereira, Sofia A.. "Paraoxonase as part of endogenous free-radical scavenging system in zebrafish". 2014.
    DOI: 10.1016/j.toxlet.2014.06.185
  35. Pereira, Sofia A.; Inês Varanda de Jesus Faustino; Lucilia Diogo; Ricardo A. Afonso; Pereira SA; E.C. Monteiro; Ana Isabel Santos. "Oral voluntary ingestion as a stress free alternative to orogastric gavage: The example of losartan chronic administration.". 2014.
    DOI: 10.1016/j.toxlet.2014.06.572
  36. Pereira, Sofia A.. "3D hepatocyte cultures: A useful tool in the study of Nevirapine bioactivation and toxicity.". Trabalho apresentado em 49th Congress of the European Societies of Toxicology (EUROTOX), 2013.
  37. Pereira, Sofia. "Relevance of CYP2C19 genotypes in Nevirapine biotransformation [oral presentation]". Trabalho apresentado em European Society of Pharmacogenomics and Theranostics (ESPT) Second Conference. Pharmacogenomics: from Cell to Clinic, 2013.
  38. Pereira, Sofia. "Effect of chronic exposure to the antiretroviral drug nevirapine on paraoxonase-1 activities in HIV-infected patients [oral presentation]". Trabalho apresentado em 2nd International Conference on Occupational & Environmental Toxicology, 2013.
  39. Pereira, Sofia. "Biomedical models for translational research [invited oral presentation]". Trabalho apresentado em 3º Congresso Internacional de Enfermagem Veterinária, 2013.
  40. Pereira SA; E.C. Monteiro. "Hemoglobin adducts from the antiretroviral abacavir in HIV-infected patients as evidence of bioactivation [oral presentation]". Trabalho apresentado em 244th ACS National Meeting & Exposition, Philadelphia, 2012.
  41. Pereira, Sofia. "Antiretrovirals and Cardiovascular disease [invited oral presentation]". Trabalho apresentado em Santa Marta Lisbon Summer Meeting, 2012.
Tese / Dissertação
  1. Pereira, Sofia de Azeredo. "Drug Monitoring of Efavirenz -applicability criteria and long-term pharmacokinetic/pharmacodynamic relations". Doutoramento, Universidade Nova de Lisboa Faculdade de Ciências Médicas, 2009. http://hdl.handle.net/10362/5210.

Propriedade Intelectual

Patente
  1. Pereira, Sofia A.; Maria Emilia Carreira Saraiva Monteiro (5918-54A6-FAA0); Aline Teixeira Marinho. 2019. "2-hydroxy-nevirapine analogues or derivatives for use in the treatment of diseases related to high density lipoprotein dysfunction. PPI 2019/20066".

Outros

Outra produção
  1. Mitoxantrone disrupts brain glutathione defence and the metabolic pathways in CD-1 mice. 2024. AD Carvalho; AM Araújo; A Reis-Mendes; CO Sequeira; Pereira SA; PG de Pinho; F Carvalho; et al. https://novaresearch.unl.pt/en/publications/240e7193-6a24-4f56-91e4-75f986b4e81a.
    10.1016/j.toxlet.2024.07.397
  2. Association Between Sarcopenia, Body Composition and Frailty in Peritoneal Dialysis Patients. A Multi-centric Study. 2023. MNP Mauricio; JH Merino; A Carnevale; Pereira SA; AR Martins; R Calça; P Matias; et al. https://novaresearch.unl.pt/en/publications/6b8ce74c-378b-4637-9ec0-c8c793d43f26.
  3. "surprise Question". Is It a Useful Tool in Ckd Stages 4 to 5?. 2023. B Pepe; T Prazeres; A Carnevale; R Calca; P Matias; P Branco; Sofia Mucharreira de Azeredo Lopes; Pereira SA; AR Martins. https://novaresearch.unl.pt/en/publications/c5708652-627f-428a-a4b6-ae62ba4053fa.
  4. Aryl hydrocarbon receptor antagonists - a new entry in antihypertensive armamentarium of obstructive sleep apnea?. 2021. Pereira SA; Nuno R. Coelho; Celine Tomkiewcz; Maria Joao Correia; Antonio B. Pimpao; Robert Barouki; Xavier Coumoul; et al. https://novaresearch.unl.pt/en/publications/53cdf1c1-8bfa-4732-8d69-e835b48bc6ce.
  5. Platelet-lymphocyte ratio as a short-term treatment-response predictor in schizophrenia's relapse. 2019. Ines Carreira Figueiredo; Ines Cargaleiro; Stephanie Mueller; Aguiar P.; Joana R Batuca; Pereira SA; Lucilia Diogo; Ilinca Ureche-Angelescu; E.C. Monteiro. https://novaresearch.unl.pt/en/publications/6527fc22-da62-4659-b971-73837deba614.
  6. KIDNEY DISEASE PROGRESSION IN HIV-INFECTED PATIENTS RELATED WITH THE DETOXIFICATION OF ENDOGENOUS ELECTROPHILIC SPECIES. 2017. Clara Dias; Pedro Campos; Lucilia Diogo; Diva Trigo; Maria Joao Correia; Ana Lemos; E.C. Monteiro; Karina Soto; Pereira SA. https://novaresearch.unl.pt/en/publications/c0be8f8e-d7bc-42e4-b0a4-96dc01936af1.
  7. Monitoring of 8-hydroxy-efavirenz concentrations for management of mood changes. 2016. Nádia Grilo; Maria Correia; Catarina Sequeira; Shrika G Harjivan; Umbelina Caixas; Lucilia Diogo; M Matilde Marques; et al. https://novaresearch.unl.pt/en/publications/d64cf9ee-431f-450a-bb5c-006a503625a9.
  8. IS THERE A ROLE FOR SOLUBLE alpha-KLOTHO IN KIDNEY AND IMMUNE DYSFUNCTION OF HIV-INFECTEDPATIENTS?. 2016. Pedro Campos; Clara G Dias; Sara Maia; Pereira SA; Ana Pires; Karina Soto. https://novaresearch.unl.pt/en/publications/44bffc04-8162-4488-917c-efcadf40539d.
  9. Sex differences in hepatic and intestinal contributions for nevirapine biotransformation. 2014. Aline Teixeira Marinho; Pereira SA; Pereira, Sofia. https://novaresearch.unl.pt/en/publications/536b5e84-a9bc-4105-ba0f-9ef2105fc200.
    DOI: 10.1016/j.toxlet.2014.06.803
  10. Monitoring of the lactonase activity of paraoxonase-1 enzyme in HIV-1-infection. 2014. Pereira SA; E.C. Monteiro; Umbelina de Jesus Albino Caixas; Judit Morello; Aline Teixeira Marinho; Clara Lúcia Gonçalves Dias. https://novaresearch.unl.pt/en/publications/634c6fad-d170-44e8-ab69-74796eb409af.
  11. An animal model to explore efavirenz toxicokinetics and its relation to neurological phenotype. 2014. Pereira SA; E.C. Monteiro. https://novaresearch.unl.pt/en/publications/b5db4ae5-daf5-4c5a-b91c-83007777b01d.
    10.1016/j.toxlet.2014.06.813
  12. Thiol status in HIV-infected patients: The effect of nevirapine metabolism. 2014. Inês Varanda de Jesus Faustino; Aline Teixeira Marinho; Clara Lúcia Gonçalves Dias; Umbelina de Jesus Albino Caixas; Pereira SA; E.C. Monteiro. https://novaresearch.unl.pt/en/publications/834768f1-7bc8-4598-87b5-55c902c26d71.
    10.1016/j.toxlet.2014.06.352
  13. Sex differences in apolipoprotein A1 and nevirapine-induced toxicity. 2014. Pereira SA; E.C. Monteiro; Clara Lúcia Gonçalves Dias; Aline Teixeira Marinho. https://novaresearch.unl.pt/en/publications/1919760a-1152-4c90-ac77-6fd3853bc7b4.
    10.7448/IAS.17.4.19575
  14. PON-1 activity as a protective player in nevirapine hepatotoxicity: Data comparison in 2D and 3D cell cultures. 2014. Aline Teixeira Marinho; Clara Lúcia Gonçalves Dias; Pereira SA; E.C. Monteiro. https://novaresearch.unl.pt/en/publications/fa585f80-cf47-47f4-a21b-6ecdebdb704a.
    10.1016/j.toxlet.2014.06.476
  15. 3D hepatocyte cultures: A useful tool in the study of Nevirapine bioactivation and toxicity. 2013. Pereira SA. https://novaresearch.unl.pt/en/publications/3f026dba-afe2-4f84-b45b-b5d77ffd642b.
  16. Mass spectrometric detection of hemoglobin adducts from the anti-HIV drug nevirapine and its metabolite 12-hydroxy-nevirapine in rats. Abstracts of Papers of the American Chemical Society. 2010. E.C. Monteiro; Pereira SA; Marques, Matilde; Godinho, Ana L. A.; Oliveira, Conceicao; Pereira, Sofia A.; Monteiro, Emilia C.; Beland, Frederick A.; Antunes, Alexandra M. M.. https://novaresearch.unl.pt/en/publications/6362d1d6-812d-425d-97d3-c107d81d38ae.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2025/02 Cysteine and peritoneal membrane fibrosis: a hypothesis-generating study. 55ª Reunião da Sociedade Portuguesa de Farmacologia
(Porto, Portugal)
2025 Renal transcriptomic signature controlled by the AhR in a model of arterial hypertension induced by Chronic intermittent hypoxia Annual meeting of the Portuguese Society of Pharmacology / XLIII Meeting of Clinical Pharmacology / XXIV Meeting of Toxicology
(Porto, Portugal)
2025 Changes induced in oxalate metabolism in rat by Chronic intermittent hypoxia LV Annual meeting of the Portuguese Society of Pharmacology / XLIII Meeting of Clinical Pharmacology / XXIV Meeting of Toxicology
(Porto, Portugal)
2024 NRF2 targeting in arterial hypertension associated with sleep apnea 8th BenBedPhar Scientific Meeting
(Lisbon, Portugal)
2024 AHR Signaling and Cysteine Metabolism in Chronic Intermittent Hypoxia-Induced Hypertension 6th International AHR Meeting
(Düsseldorf, Alemanha)
2024 Aryl Hydrocarbon Receptor And Cysteine Metabolism In Liver: Impact Of The Chronicity Of Intermittent Hypoxia LIV Annual meeting of the Portuguese Society of Pharmacology / XLII Meeting of Clinical Pharmacology / XXIII Meeting of Toxicology
(Lisbon, Portugal)
2023/03/21 Environmental Phenotypes of Kidney related diseases LS4Future Meeting
(Vimeiro, Portugal)
2023/02/03 Core concepts in pharmacokinetics for the integrated Master´s degree in medicine: a multidisciplinary approach 53rd Meeting of the Portuguese Society of Pharmacology
Portuguese Society of Pharmacology (Coimbra, Portugal)
2023 Hydroxytyrosol (Ohtyr) Reverts Renal Aryl Hydrocarbon Receptor (Ahr) Canonical Activation Induced By Chronic Intermittent Hypoxia LIII Annual meeting of the Portuguese Society of Pharmacology / XLI Meeting of Clinical Pharmacology / XXII Meeting of Toxicology
(Lisbon, Portugal)
2022/10/11 Activation of the aryl hydrocarbon receptor in the kidney. Implications & Consequences Translational Nephrology Building the bridge from the bench-to-bedside
Portuguese Society of Nephrology (Setúbal)
2022/06 Renal functinal Reserve - how to assess it? II Rim do desportista, Hospital das Forças Armadas, Lisboa Rim Desportista
Hospital das forças Armadas
2022 Pharmacometabolomics of sulfonation: Urinary metabolite profile can predict sulfonation capacity in man. 40ª Reunião de Farmacologia Clínica e 21ª Reunião de Toxicologia./ XXXIX Reunião de Farmacologia Clínica/ XX Reunião de Toxicologia
Porto Palácio by The Editory - The Editory Collection Hotels (Porto, Portugal)
2022 Renal AHR-CYP1A1 activation by chronic intermittent hypoxia is related to arterial hypertension and depends on IH chronicity and chronobiology XXI ISAC Meeting
(Lisbon, Portugal)
2022 The Antihypertensive Effect of Hydroxytyrosol in A Model of Hypertension Induced by Chronic Intermittent Hypoxia is Associated with Tryptophan Metabolism XXI ISAC Meeting
(Lisbon, Portugal)
2021/02/19 CYSTEINE OXIDATION IS A PUTATIVE AHR ACTIVATOR IN KIDNEY CORTEX (MAL)ADAPTATION TO CHRONIC INTERMITTENT HYPOXIA CONDITIONS SPF Meeting 2021
Sociedade Portuguesa de Farmacologia; Faculdade de Farmácia da Universidade de Lisboa (Lisbon, Portugal)
2021/02/19 NOVEL MECHANISMS IN ANGIOGENESIS: OXIDATIVE STRESS AS A PROMOTER OF MONOCYTE-TO-ENDOTHELIAL CELL DIFFERENTIATION AND ENDOTHELIAL CELL ACTIVATION SPF Meeting 2021
Sociedade Portuguesa de Farmacologia; Faculdade de Farmácia da Universidade de Lisboa (Lisbon, Portugal)
2021/02/17 IMPACT OF CHRONIC INTERMITTENT HYPOXIA ON TRYPTOPHAN METABOLISM SPF Meeting 2021
Sociedade Portuguesa de Farmacologia; Faculdade de Farmácia da Universidade de Lisboa (Lisbon, Portugal)
2021/02/17 PHARMACOLOGICAL PATHWAYS OF THE AHR ANTAGONIST CH-223191 IN KIDNEY IN A MODEL OF ARTERIAL HYPERTENSION ASSOCIATED TO SLEEP APNEA SPF Meeting 2021
Sociedade Portuguesa de Farmacologia; Faculdade de Farmácia da Universidade de Lisboa (Lisbon, Portugal)
2021 Why is the AhR pathway activated at kidney in a model of hypertension associated to obstructive sleep apnea? A focus on tryptophan metabolism XXXV Congresso Português de Nefrologia
Sociedade Portuguesa Nefrologia (Vilamora)
2021 A bet in olive oil: hydroxytyrosol reverts increased blood pressure and cysteine disulfides induced by chronic intermittent hypoxia ISAC XXI VIRTUAL KICKOFF MEETING
Nova Medical School
2021 Hydroxytyrosol is a potential modulator of cysteine redox dynamics and controls increased blood pressure in a model of hypertension associated to obstructive sleep apnea 3rd NMS Symposium on Chronic Diseases and Translational Science
CEDOC (Lisbon, Portugal)
2021 Aryl hydrocarbon receptor antagonists - a new entry in antihypertensive armamentarium of obstructive sleep apnea? ESH-ISH Joint Meeting
(Glasgow, Reino Unido)
2021 Why is the AhR pathway activated at kidney in a model of hypertension associated to obstructive sleep apnea? A focus on tryptophan metabolism Renal Meeting
(Vilamoura, Portugal)
2020 Effect of hydroxytyrosol in hypertension induced by chronic intermittent hypoxia L Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXVIII Reunião de Farmacologia Clínica/ XIX Reunião de Toxicologia
Faculdade de Farmácia da Universidade de Coimbra (Coimbra, Portugal)
2020 The antihypertensive effect of AHR antagonist is related to circadian variation of blood pressure in Chronic Intermittent Hypoxia condition L Reunião Anual da Sociedade Portuguesa de Farmacologia/ XXXVIII Reunião de Farmacologia Clínica/ XIX Reunião de Toxicologia
(Coimbra, Portugal)
2020 Kidney participation in drug metabolism – opportunities to investigate new players in hypertension 1ª Reunião do ´´Núcleo de Nefrologia de Translação´´
Sociedade Portuguesa Nefrologia (Coimbra, Portugal)
2020 Lesson within Framework of international communication and cooperation between educators/ teachers of clinical pharmacology.
Masaryk University – Fakulty of Medicine (Brno, República Checa)
2019/05/10 Phenotyping the mercapturate pathway to address kidney tubular function. Casual Friday with Science
Centro de estudos de doenças crónicas, Universidade Nova de Lisboa Faculdade de Ciências Médicas (Lisboa, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2022/09/01 - Atual Determinants of the activation of the AhR-Cyp1a1 axis in kidney in arterial hypertension associated to obstructive sleep apnea: a matter of agonist and intermittent hypoxia
Orientador
 Health Sciences (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2020/09/01 - Atual Precision Urology: Metabolic Phenotype of Patients with Metabolic Syndrome and Recurrent Nephrolithiasis
Coorientador
 Health Sciences - Medicine (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2018/09/01 - Atual Emerging roles of (per)Sulfidome in Kidney Disease
Coorientador
 Molecular Biosciences (Doutoramento)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2017/09 - 2022/03/24 Hydroxytyrosol and hypertension associated with chronic intermittent hypoxia: impact and contribution of AhR alternative pathway
Orientador de Maria João Andrade Correia
 Biomedicine (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2017 - 2022 Variability of sulfotransferase 1A1 (SULT1A1) activity in humans: an approach to improve predictive drug response.
Coorientador de Natália Carvalheira de Freitas Marto
 Medicine (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2020 - 2021/01 Targeting AhR metabolic circuitry for better management of arterial hypertension in obstructive sleep apneia.
Orientador de António Pimpão
 Genética Molecular e Biomedicina (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017 - 2021 Monocytes as neoangiogenesis promoters and anti-cancer targets.
Coorientador de Filipa Lopes Coelho
 Mechanisms of disease and Regenerative Medicine (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2015 - 2020 Systemic Lupus Erythematosus: development of methodologies based on the technique of mass spectrometry for the diagnosis / prognosis of the disease.
Coorientador de Catarina Sofia Romão Charneira
 Chemistry (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2020 Aryl hydrocarbon receptor (AhR): a therapeutic target for systemic hypertension associated with chronic intermittent hypoxia.
Coorientador de Nuno Filipe Ramos Coelho
 Mecanismos de Doença e Medicina Regenerativa (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2014 - 2019 Investigating the role of the mercapturate pathway in kidney function for the identification of an early indicator tubular dysfunction.
Orientador de Clara Lúcia Gonçalves Dias
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2014 - 2019 Cysteine, a facilitator of hypoxia adaptation and a promoter of drug resistance- a new route to better diagnose and treat ovarian cancer patients.
Coorientador de Ana Sofia de Almeida da Costa Nunes
 Mecanismos de Doença e Medicina Regenerativa (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2014 - 2018 Teaching an old drug new tricks: reprofiling of nevirapine as an HDL modulator. Individual PhD Fellowship SFRH/BD/92191/2013
Orientador de Aline Teixeira Marinho
 Mechanisms of Disease and Regenerative Medicine (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2016/10 - 2017 Changes in N-acetyltransferase 8 in kidney tubular cell: Injury, recovery and mesenchymal stem/stromal cell treatment.
Orientador de Patrícia Canotilho dos Santos Grácio
 Ciências de Engenharia - Engenharia Biomédica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013 - 2017 The anti-HIV drug Efavirenz: a challenge on molecular mechanisms of drug associated neurocognitive disorders. Individual PhD Fellowship SFRH/BD/86791/2012.
Orientador de Nádia Filipa Marques Grilo
 Ciências da Vida (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2015 - 2016 S-thiolated protein profile to assess the redox modulation effects of antiretroviral drugs.
Orientador de Maria João Correia
 Genética Molecular e Biomedicina (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014 - 2015 Molecular targeting of proteins by homocysteine in clinical and familial hypercholesterolemia.
Orientador de Ana Rita Lemos
 Genética Molecular e Biomedicina (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014 - 2015 Usefulness of zebrafish model to assessglomerular and tubular alterationsinduced by tenofovir.
Coorientador de Rita Gorgulho
 Genética Molecular e Biomedicina (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013 - 2015 Zebrafish as a model for toxicological studies: is there a role for Paraoxonase?
Orientador de Lara Andreia Pires Afonso
 Biologia Humana e Ambiente (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
2012 - 2013 Nevirapine biotransformation in a type II diabetes model.
Orientador de Patricia Marques Rodrigues
 Biotecnologia (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012 - 2013 HDL in HIV-1 infection: a quality perspective through paraoxonase-1 activities.
Orientador de Clara Dias
 Genética Molecular e Biomedicina (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012 - 2013 New insights on nevirapine use: A mechanistic perspective of its toxic events.
Orientador de Aline Teixeira Marinho
 Ciências Biomédicas (Mestrado)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2011 - 2012 Protein adducts from the anti-HIV drug abacavir – possible biomarkers of drug toxicity.
Orientador de Nádia Filipa Marques Grilo
 Genética Molecular e Biomedicina (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2024/02/07 - 2024/02/09 Organisation of the 54th Meeting of the Portuguese Society of Pharmacology, 42nd Meeting of Clinical Pharmacology and 23rd Meeting of Toxicology (2024/02/07 - 2024/02/09)
Encontro (Membro da Comissão Organizadora)
 Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2014 - 2015 Organization of the Meeting of the Portguese Society of Pharmacology 2015 (2015 - 2015)
Encontro (Membro da Comissão Organizadora)
 Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2021 - Atual Chair of Cardiovascular & Renal Pharmacology session
Congresso
 3rd NMS Symposium on Chronic Diseases and Translational Science
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
2014 - Atual Pariticipation in the OPEN DAYS of the institute (outreach activities).
Outro
 CEDOC Open Days
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
2021/04/11 - 2021/04/14 ESH-ISH Joint Meeting - Hypertension meeting participation
Encontro
 ESH-ISH Joint Meeting
2012 - 2020 Chariwomen at several (pharmacology, cancer, toxicology) sessions at SPF meetings
Encontro
 SPF meeting
Sociedade Portuguesa de Farmacologia, Portugal
2019/09/04 - 2019/09/06 Co-author of one of the works presented: Effect of cysteinyl- S-conjugates on the function and structure of human enzymes involved in hydrogen sulfide metabolism
Encontro
 NOVABiophysica
Universidade Nova de Lisboa, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2022/07/20 In Vivo Phenotyping of Sult1a enzymes in man: implications for precision medicine
Orientador
 Natália Marto (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2022/02/23 "Nose-to-brain Delivery of Lacosamide, Levetiracetam and Zonisamide and the Impact of BCRP Efflux: an In Vitro/In Vivo Approach".
Arguente
 Joana Carrapiço Gonçalves (Doutoramento)
Universidade de Coimbra, Portugal
2021/12/20 "Targeting the carotid bodies to treat obesity"
Arguente
 Bernardete Sofia Freitas de Melo. (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2021/01/26 "Development of point-of-care tests using enzyme (NiR & PON) based electrochemical biosensors."
Vogal
 Tiago Carvalho Monteiro (Mestrado)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2020/12/09 The neurotoxicity of doxorubicin and mitoxantrone: chemobrain studies using infant, adult, and old mice.
Arguente
 Ana Rita Constantino Dias de Carvalho (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/01 Evaluation to recognition of foreign qualifications at the level of Doctorate of the thesis “Regulation of Clostridium acetobutylicum glutamine synthetase glnA gene”. Ivo Pedro Fierro-Monti (Doutoramento)
2020 Metabolomics of Menopause in HIV-infected women
Arguente
 Cláudia Nunes (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
2019/11/28 Characterization and modulation of the Renin-Angiotensin System in Diabetic Retinopathy.
Arguente
 Brigite Ladeira Cabrita (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/02/19 Bioanalytical tools for unraveling part of the puzzle of the biochemical phenomena in epilepsy: neuromediators and antiepileptic drugs
Arguente
 Beatriz Marques da Fonseca (Doutoramento)
Universidade da Beira Interior, Portugal
2017 Estratégias in vitro e in vivo para o estudo da bioativação do fármaco anti-HIV Etravirina
Arguente
 Ana Godinho (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 Development of three-dimensional umbilical cord-derived cell culture for differentiation into hepatocyte-like cells: a potential breakthrough in toxicological drug screening
Arguente
 Madalena Cipriano (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015 Bioactivação do fármaco anti-VIH Nevirapina: quantificação por espectrometria de massa de alta resolução de adutos covalentes formados com a hemoglobina.
Arguente
 Catarina Oliveira (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014 Evaluation of the therapeutic potential of the umbilical cord tissue-derived mesenchymal stromal cells (UCX®) 3D cultures for tissue regeneration
Arguente
 Sérgio Camões (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
2012 Metabolitos fenólicos do fármaco anti-HIV Nevirapina: Mecanismos de bioactivação em culturas 3D de hepatócitos de rato
Arguente
 Pedro Pinheiro (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Arbitragem científica em conferência

Nome da conferência Local da conferência
2015 - Atual Meeting of the Portuguese Society of Pharmacology Faculdade de Ciências Médicas de Lisboa
2021/06/16 - 2021/06/18 Third CEDOC Symposium on Chronic Diseases and Translational Science CEDOC-NMS
2021/02/17 - 2021/02/17 3rd NMS Symposium on Chronic Diseases and Translational Science CEDOC|NMS
2017 - 2017 VI in4Med Faculdade de Medicina, Universidade de Coimbra

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2021/10/31 - Atual MPDI - Special Issue "Small Molecules: A Field of Opportunities for Differential Diagnosis and Precision Medicine" (1420-3049)
2021/09/30 - Atual Frontiers in Pharmacology - Non-Cytochrome P450 Enzymes and Extra-Hepatic Drug Metabolism: Challenges and Opportunities (1663-9812 ) Frontiers
2020/02/20 - 2020/02/20 Frontiers - Metabolomics in Toxicology: From Mechanistic Elucidation to Preventive and Therapeutic Strategies Frontiers
2019/03/31 - 2019/03/31 High-throughput - Special Issue "Adductomics: Elucidating the Environmental Causes of Disease" (2571-5135) MDPI

Comissão de avaliação

Descrição da atividade
Tipo de assessoria 		Instituição / Organização Entidade financiadora
2022 - Atual 2022 PhD grant evaluation in the area of Biomedicine
Avaliador
 Fundação para a Ciência e a Tecnologia, Portugal
2013 - Atual Prize Astrazeneca Innovate Foundation at iMed Conference.
Avaliador
 Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2021/09/30 - 2021/10/02 Juri - Best poster - 12 Topics in Rheumatology meeting Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2021 - 2021 PhD grant evaluation in the area of Clinical Medicine and Health Sciences.
Avaliador
 Fundação para a Ciência e a Tecnologia, Portugal
2020/03 - 2020/04 ´´RESEARCH 4 COVID-19``: Evaluation of R&D projects and initiatives that respond to the needs of the National Health Service (SNS) in response to this and future pandemics in a very short time horizon.
Avaliador
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
2020/03/06 - 2020/03/07 Juri - Best poster - 12 Topics in Rheumatology meeting Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2012 - 2015 Pfizer Prizes for biomedical research projects in Portugal
Avaliador
 Universidade Nova de Lisboa Faculdade de Ciências Médicas
2012 - 2012 Evaluation Panel of PhD programme in Life Sciences
Avaliador
 Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2020 - Atual Teaching in Curricular Unit of Integrative Biomedicine of Biomedicine PhD 1st Year BIOMEDICINE PhD Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2020 - Atual Clinical pharmacology within the framework of international communication and cooperation between educators/ teachers of clinical pharmacology. Medicine (Bachelor (1.º ciclo de estudos)) Masarykova univerzita, República Checa
2018 - Atual Master NOVA Biomedical Research. Curriular Unit "Aging and chronic diseases: from molecular mechanisms to therapies" NOVA Biomedical Research (Mestrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2013 - Atual Integrated Master Degree in Medicine. Nuclear curricular unit "Infection: aetiology, pathogenesis and therapeutics; practical classes, elaboration and correction of tests". Medicina (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2012 - Atual Integrated Master Degree in Medicine. Nuclear curricular unit "General Pharmacology; theoretical and practical classes, elaboration and correction of tests". Medicina (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2012 - Atual Integrated Master Degree in Medicine. Nuclear curricular unit of Phatophysiology and Therapeutic Targets; theoretical and practical classes, elaboration and correction of tests. Medicina (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2012 - Atual PhD Program "Life Sciences". Lecture Translational Research. Ciências da Vida (Doutoramento) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2020/06/05 - 2020/06/06 Seminar - NOVA Biomedical Research Master Seminars (Mestrado)
2016 - 2017 Integrated Master Degree in Medicine. Optional curricular unit "Methods for the quantification of endogenous metabolites in biological fluids" Medicina (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2015 - 2017 Master in Clinical Trials and Medical Affairs Master em Monitorização de Ensaios Clínicos e Medical Affairs (Mestrado) Centro de Estudos Superiores da Indústria Farmacêutica, Portugal
2013 - 2015 Integrated Master Degree in Medicine. Optional curricular unit "Translational Medicine in Chronic Diseases and Aging". Topic: "Pharmacogenomics, ratios of metabolites and metabolic phenotypes". Medicina (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2013 - 2015 PhD Program "Mechanisms of Disease and Regenerative Medicine". Curricular unit "Degenerative and Chronic Diseases" . Topic: "Drug toxicity as mechanism of disease. The roleof antiretroviral drug toxicity: from cell to clinic". Mecanismos de Doença e Medicina Regenerativa (Doutoramento) Universidade do Algarve, Portugal

Universidade Nova de Lisboa, Portugal
2012 - 2013 Integrated Master Degree in Medicine. Topics: "Pharmacokinetics", Drug toxicity", "Drugs inhibiting Cellular Proliferation", "Variability in Drug Response" Medicina (Mestrado integrado) Universidade do Algarve, Portugal
2006 - 2007 Postgraduate Course in Monitoring of Clinical Trials. Lecture in Pharmacokinetics Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2019/11/15 Environmental changes: Pollution as an atherogenic factor Journal NewsFarma CONGRESSO (XXVII Congresso Português de Aterosclerose)

Membro de associação

Nome da associação Tipo de participação
2022 - Atual COST Action CA20121 Bench to Bedside transition for Pharmacological regulation of NRF2 in non communicable diseases Member
2016 - Atual Portuguese Society of Nephrology
2007 - Atual Portuguese Society of Pharmacology
2020 - 2024 CA19115 - Network for blood pressure research in children and adolescents. (https://www.cost.eu/actions/CA19115/#tabs|Name:overview) Member
2020 - 2024 CA19127 - Cognitive decline in Nephro-Neurology: European Cooperative Target. (https://www.cost.eu/actions/CA19127/#tabs|Name:overview) Member
2016 - 2020 Diagnosis, Monitoring and Prevention of exposure related non-communicable diseases, DiMoPEx (CA 15129) Member
2005 - 2011 SIDAnet Portuguese Association Secretary

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2023/02 - Atual NMS Research area Cardiovasular, renal and metabolic diseases
Coordenador
 Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019/04/24 - Atual Coordinator of the Pedagogical Committee of the 2nd year of the Integrated Master in Medicine.
Coordenador
 Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2021 - 2021 Selection of abstracts at iMed Conference® 13.0
Consultor
 Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2018 - 2019 Development of guidelines and evaluation structure for the course: Thesis within the scope of the PhD in Biomedicine PhD
Presidente / Vice-presidente
 Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2014 - 2019 Member of the Scientific Committee of the Faculdade de Ciências Médicas de Lisboa
Membro
 Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2022 - 2023 Jury for the application procedure for the PhD in Biomedicine Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019 - 2020/07/02 Evaluation of the Student Rita Coelho at PROJECT IN CELL AND MOLECULAR BIOLOGY discipline Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019 - 2020/07/02 Evaluation of the student Joana Reis at PROJECT IN CELL AND MOLECULAR BIOLOGY discipline Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/07/09 - 2020 Analysis, evaluation and selection of doctoral applications in biomedicine -5th edition (Academic year of 2019/2020). Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019/07 - 2019/07 Jury on evaluation of master thesis plan of 2 students on NBR master course. Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019/05/24 - 2019/05/24 International selection procedure for hiring a Doctorate under Articles 18 and 20 of Decree-Law No. 57/2016, of 29 August, amended by Law No. 57/2017. (Aviso n.º 9148/2019) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019 - 2019 Evaluation of doctoral intention in medicine of the project´´The effect of preoperative dexamethasone on postimplantation syndrome after endovascular aneurysm repair - protocol for a randomized controlled trial´´ from the student Ana Rita Pinho Soares Ferreira. Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2016 - 2016 Jury of the public tender to contrat a Superior Technician at Faculdade de Ciências Médicas de Lisboa. Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2014 - 2014 Evaluation of the experimental period of the Superior Technician Inês Varanda de Jesus Faustino Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2011 - 2011 Jury of the public tender to contrat a Superior Technician at Faculdade de Ciências Médicas de Lisboa. Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Tutoria

Tópico Nome do aluno
2020 - Atual Portugal Clinical Scholars Research Training (PTCSRT) Clara Matos
Distinções

Prémio

2024 Prémio DAVITA 2024. Klotho and learn mass as novel cardiovascular risk factors in hemodialysis patients. Best work in hemodialysis
2024 Prémio Baxter 2024. Fibrosis of Peritoneal Membrane, Molecular Indicators of Aging and Frailty Unveil Vulnerable Patients in Long-Term Peritoneal Dialysis. Best work in Peritoneal Dialysis.is
2024 Prémio Dr. Carlos Lima para investigação clínica. Alpha-klotho and peritoneal membrane status: A hypothesis generating study.
2022 Best work submitted in Basic Nephrology
2022 DeCastro-Heymans-Neil Award" Best Oral Presentation 3rd Prize (for best oral presentation) Renal AHR-CYP1A1 activation by chronic intermittent hypoxia is related to arterial hypertension and depends on its chronicity.
2022 Bolsa de Investigação em Urologia 2022
Sociedade Portuguesa de Neurologia, Portugal
2022 Precision Urology: Metabolic Phenotype of Patients with Metabolic Syndrome Traits and Recurrent Nephrolithiasis – Metabolomics and Recurrence Assessment
2021 Best work submitted in Basic Nephrology
Sociedade Portuguesa de Nefrologia, Portugal
2017 Best work submitted in Basic Nephrology
Sociedade Portuguesa de Nefrologia, Portugal
2017 Travel Grant. Thiol oxidation in toxicity and signaling workshop organized by EMBO
2015 Gilead GÉNESE Portugal Program. PGG/032/2015 – Renal tubular lesion in HIV-infected patients: progression and interaction. (PGG/032/2015).
Gilead Sciences Lda, Portugal
2013 Project: HIV-Nefromics - Novel markers of antiretroviral induced nephrotoxicity in HIV infected patients
Sociedade Portuguesa de Nefrologia, Portugal
2013 Best Oral Presentation on the "2nd International Conference on Occupational & Environmental Toxicology", Journals of Toxicology and Environmental Health and Taylor & Francis Group
2013 Honoroble mention for best poster on the "5.0 iMed Conference"
2011 ERASMUS Movility Grant for training at the Pharmacy & Pharmacology Department of Slotervaart Hospital, Amsterdam, Holland
2009 Research Fellowship Luso-American Development Foundation (FLAD)
2004 Best oral presentation - clinical case. VI Jornadas de Infecção pelo VIH
Sociedade Portuguesa de Medicina Interna, Portugal
2002 BIC fellowship
Fundação para a Ciência e a Tecnologia, Portugal
2001 Program of stays in superior education (Prodept). PRODEP III MEDIDA 3 ACÇÃO, public call n1/3.2/PRODEP/2002
2001 PRODEPT fellowship

Outra distinção

2018 Prémio melhor comunicação em painel Clara G. Dias, Nuno R. Coelho, Maria J. Correia, Filipa Lopes-Coelho, Maria J. Meneses, Inês Sousa-Lima, Jacinta Serpa, Maria P. Macedo, Karina Soto, Emília C. Monteiro, Sofia A. Pereira. Renal cysteine-disulfide stress