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Filipa Lebre. Completed the Mestrado integrado in Ciências Farmacêuticas in 2008 by Universidade de Coimbra and Doutoramento in Doutoramento em Tecnologia Farmacêutica in 2017 by Universidade de Coimbra Faculdade de Farmácia. Is Researcher in International Iberian Nanotechnology Laboratory. Published 21 articles in journals. Has 1 book(s). Organized 4 event(s). Participated in 37 event(s). Co-supervised 3 MSc dissertation(s). Supervised 1 work(s) of course completion of LSc/BSc e co-supervised 5. Has received 3 awards and/or honors. Participates and/or participated as Co-Principal Investigator (Co-PI) in 1 project(s), Post-doc Fellow in 1 project(s), Principal investigator in 1 project(s) and Researcher in 1 project(s). Works in the area(s) of Medical and Health Sciences with emphasis on Medical Biotechnology with emphasis on Biomaterials, Medical and Health Sciences with emphasis on Basic Medicine with emphasis on Immunology, Medical and Health Sciences with emphasis on Medical Biotechnology with emphasis on Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism and Medical and Health Sciences with emphasis on Medical Biotechnology with emphasis on Health-Related Biotechnology. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: nanoparticles; vaccines; chitosan; hepatitis B antigen; DNA; mucosal vaccination; nasal administration; adjuvant association; Domínio/Área Científica::Ciências Médicas::Ciências da Saúde; Molecular Mechanisms of Brain Diseases; Vision and Brain; Aging and Metabolic Dysfunction; Stem Cells Biotechnology; Neurodegenerative disorders; Stem Cells; Mitochondria; Drug Carriers; .
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Identificação

Identificação pessoal

Nome completo
Filipa Lebre

Nomes de citação

  • Lebre, Filipa

Identificadores de autor

Ciência ID
7017-F931-4DE5
ORCID iD
0000-0003-3146-269X
Google Scholar ID
https://scholar.google.com/citations?user=uEqlV6wAAAAJ&hl=en
Scopus Author Id
36480377300

Endereços de correio eletrónico

  • filipa.lebre@inl.int (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais
  • Ciências Médicas e da Saúde - Medicina Básica - Imunologia
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biotecnologia Aplicada à Saúde

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador independente (B1)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador independente (B1)
Formação
Grau Classificação
2023/03/30
Concluído
 Data Integrity and Good Documentation Practices (Outros)
Qualipharma, Espanha
2023/03/23
Concluído
 Deviations, CAPAs & Change Controls (Outros)
Qualipharma, Espanha
2022/11/29 - 2022/11/29
Concluído
 Good Laboratory Practices (GLP) (Outros)
Qualipharma, Espanha
2019
Concluído
 Epigeum training (Outros)
Epigeum, Reino Unido
 Aprovado
2010 - 2017
Concluído
 Doutoramento em Tecnologia Farmacêutica (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
"Development of chitosan-based nanoparticles for nasal immunization against hepatitis B" (TESE/DISSERTAÇÃO)
 Aprovado com Distinção e Louvor
2016
Concluído
 LAST Ireland - Animal surgery course (Outros)
University College Dublin, Irlanda
2012/09/01 - 2013/03/31
Concluído
 Visiting PhD student, Trinity Biomedical Sciences Institute (Outros)
The University of Dublin Trinity College, Irlanda
2012
Concluído
 Vaccine Immunology with Exploration of Immune Response to Mucosal Vaccines (Outros)
Universidade de Coimbra, Portugal
2011
Concluído
 Laboratory Animal Science Course - Cat C (FELASA). (Outros)
Institute for Molecular and Cell Biology, Portugal
2010/05/01 - 2010/06/30
Concluído
 Visiting PhD student (Outros)
Ecole de Pharmacie Gèneve-Lausanne, Suiça
2010
Concluído
 MIT Principles and Practice of Drug Development (Outros)
Center of Neuroscience and Cell Biology, Portugal
2003 - 2008
Concluído
 Ciências Farmacêuticas (Mestrado integrado)
Universidade de Coimbra, Portugal
"Não aplicável" (TESE/DISSERTAÇÃO)
 15 valores
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2021/11/02 - Atual Investigador (Investigação) International Iberian Nanotechnology Laboratory, Portugal
2019/06 - 2020/11/30 Investigador principal (carreira) (Investigação) Science Foundation Ireland, Irlanda
2017/10 - 2019/05 Pós-doutorado (Investigação) Trinity College of Dublin, Irlanda
2014/05 - 2017/09 Assistente de Investigação (carreira) (Investigação) The University of Dublin Trinity College, Irlanda
2010/05 - 2014/04 Investigador (Investigação) Universidade de Coimbra, Portugal
2010/05 - 2014/04 Investigador (Investigação) Center of Neuroscience and Cell Biology, Portugal
Projetos

Bolsa

Designação Financiadores
2010/05/01 - 2014/04/30 DEVELOPMENT OF CHITOSAN-BASED NANOPARTICLES FOR NASAL IMMUNIZATION AGAINST HEPATITIS B
SFRH/BD/64046/2009
Harvard Medical School, Estados Unidos

Universidade de Coimbra Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2021/11 - 2025/01 SiNfONiA
857253
Investigador
International Iberian Nanotechnology Laboratory, Portugal
 Horizon 2020
Em curso
2022 - 2022 Development of advanced 3D in vitro alveolar model and application for nanosafety screening
2022.07049.PTDC
Co-Investigador Responsável (Co-IR)
Não financiado
2019/06/01 - 2020/11/30 Bioactive Drug Incorporation into 3D Bioprinted Scaffolds for Oncological Application
18/IF/6316
Investigador responsável
Johnson & Johnson 3D Bioprinting Center, Irlanda
 Science Foundation Ireland
Concluído
2019/01/01 - 2019/12/31 CNC. IBILI
UID/NEU/04539/2019
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2014/05 - 2019/06 Advanced Materials and BioEngineering Research Centre (AMBER)
SFI/12/RC/2278
Bolseiro de Pós-Doutoramento
Trinity College of Dublin, Irlanda
Concluído
2011/01/01 - 2012/12/31 Strategic Project - LA 1 - 2011-2012
PEst-C/SAU/LA0001/2011
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Lebre, Filipa; Rukmani Sridharan; Michael Sawkins; Daniel Kelly; Fergal O'Brien; Lavelle, Ed C.. "Hydroxyapatite particle size controls the induction of inflammatory responses suggesting the need to specifically tailor particle size for the development of regenerative implants". Trabalho apresentado em Irish Society for Immunology meeting, Dublin, 2015.
    Publicado
  2. Lebre, Filipa; Rukmani Sridharan; Michael Sawkins; Daniel Kelly; Fergal O'Brien; Lavelle, Ed C.. "Immunomodulatory properties of hydroxyapatite particles". Trabalho apresentado em AMBER review, Dublin, 2015.
    Publicado
  3. Bento, Dulce; Lebre, Filipa; Ed Lavelle; Herman Staats; Lima, Maria Conceição Pedroso; Borges, Olga. "Chitosan combined with immunopotentiators as vaccine adjuvants: Are there any advantages?". Trabalho apresentado em 7th Vaccine and ISV Annual Congress, Barcelona, 2013.
    Publicado
Artigo em revista
  1. Sankar, Siva Nemala; Araujo, Guilherme; Fernandes, João; Cerqueira, Fatima; Alpuim, Pedro; Ribeiro, Ana R.; Lebre, Filipa; et al. "Eco-Friendly Production of 2D Ti3C2Tx MXene and Cytotoxicity Mitigation Toward Biomedical Applications". Advanced Materials Interfaces 11 24 (2024): https://doi.org/10.1002/admi.202400203.
    10.1002/admi.202400203
  2. Eleftheria Maria Panagiotou; Anastasios Damdimopoulos; Tianyi Li; Elisabeth Moussaud-Lamodière; Mikael Pedersen; Filipa Lebre; Karin Pettersson; et al. "Exposure to the phthalate metabolite MEHP impacts survival and growth of human ovarian follicles in vitro". Toxicology (2024): http://dx.doi.org/10.1016/j.tox.2024.153815.
    10.1016/j.tox.2024.153815
  3. Jie Hao; Tianyi Li; Manuel Heinzelmann; Elisabeth Moussaud-Lamodière; Filipa Lebre; Kaarel Krjutškov; Anastasios Damdimopoulos; et al. "Effects of chemical in vitro activation versus fragmentation on human ovarian tissue and follicle growth in culture". Human Reproduction Open (2024): http://dx.doi.org/10.1093/hropen/hoae028.
    10.1093/hropen/hoae028
  4. Sandra Jesus; João Panão Costa; Mariana Colaço; Filipa Lebre; Daniela Mateus; Ana Isabel Sebastião; Maria T. Cruz; Ernesto Alfaro-Moreno; Olga Borges. "Exploring the immunomodulatory properties of glucan particles in human primary cells". International Journal of Pharmaceutics (2024): http://dx.doi.org/10.1016/j.ijpharm.2024.123996.
    10.1016/j.ijpharm.2024.123996
  5. S. Costa; V. Vilas-Boas; F. Lebre; J.M. Granjeiro; C.M. Catarino; L. Moreira Teixeira; P. Loskill; E. Alfaro-Moreno; A.R. Ribeiro. "Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials". Trends in Biotechnology (2023): http://dx.doi.org/10.1016/j.tibtech.2023.05.009.
    10.1016/j.tibtech.2023.05.009
  6. Mimmi L. E. Lundahl; Morgane Mitermite; Dylan Gerard Ryan; Sarah Case; Niamh C Williams; Ming Yang; Roisin I Lynch; et al. "Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses". eLife (2022): http://dx.doi.org/10.7554/elife.74690.
    10.7554/elife.74690
  7. Lebre, Filipa; Chatterjee, Nivedita; Costa, Samantha; Fernández-de-Gortari, Eli; Lopes, Carla; Meneses, João; Ortiz, Luís; et al. "Nanosafety: An Evolving Concept to Bring the Safest Possible Nanomaterials to Society and Environment". Nanomaterials 12 11 (2022): 1810. http://dx.doi.org/10.3390/nano12111810.
    10.3390/nano12111810
  8. Lundahl, Mimmi; Lynch, Dylan M.; Barnes, Danielle; McSweeney, Lauren; Gorman, Aoife; Lebre, Filipa; Gordon, Stephen V.; Lavelle, Ed C.; Scanlan, Eoin M.. "Mycobacterial para Hydroxybenzoic Acid-Derivatives (pHBADs) and Related Structures Induce Macrophage Innate Memory". ACS Chemical Biology (2020): http://dx.doi.org/10.1021/acschembio.0c00378.
    10.1021/acschembio.0c00378
  9. Shears, R.K.; Jacques, L.C.; Naylor, G.; Miyashita, L.; Khandaker, S.; Lebre, F.; Lavelle, E.C.; et al. "Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease". Journal of Allergy and Clinical Immunology 145 4 (2020): 1272-1284.e6. http://www.scopus.com/inward/record.url?eid=2-s2.0-85082558281&partnerID=MN8TOARS.
    10.1016/j.jaci.2019.11.039
  10. Lebre, F.; Boland, J.B.; Gouveia, P.; Gorman, A.L.; Lundahl, M.L.E.; I Lynch, R.; O'Brien, F.J.; Coleman, J.; Lavelle, E.C.. "Pristine graphene induces innate immune training". Nanoscale 12 20 (2020): 11192-11200. http://www.scopus.com/inward/record.url?eid=2-s2.0-85085586320&partnerID=MN8TOARS.
    Publicado • 10.1039/c9nr09661b
  11. Lebre, Filipa. "Easy and effective method to generate endotoxin-free chitosan particles for immunotoxicology and immunopharmacology studies". Journal of Pharmacy and Pharmacology (2019): http://dx.doi.org/10.1111/jphp.13082.
    10.1111/jphp.13082
  12. Lebre, Filipa. "Chitosan Plus Compound 48/80: Formulation and Preliminary Evaluation as a Hepatitis B Vaccine Adjuvant". Pharmaceutics (2019): http://dx.doi.org/10.3390/pharmaceutics11020072.
    10.3390/pharmaceutics11020072
  13. Lebre, Filipa. "Exfoliation in Endotoxin-Free Albumin Generates Pristine Graphene with Reduced Inflammatory Properties". Advanced Biosystems (2018): http://dx.doi.org/10.1002/adbi.201800102.
    10.1002/adbi.201800102
  14. Lebre, F.; Pedroso de Lima, M.C.; Lavelle, E.C.; Borges, O.. "Mechanistic study of the adjuvant effect of chitosan-aluminum nanoparticles". International Journal of Pharmaceutics 552 1-2 (2018): 7-15. http://www.scopus.com/inward/record.url?eid=2-s2.0-85053833190&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2018.09.044
  15. Moore, Caroline; Movia, Dania; Smith, Ronan J; Hanlon, Damien; Lebre, Filipa; Lavelle, Ed C.; Byrne, Hugh J; et al. "Industrial grade 2D molybdenum disulphide (MoS2): an in vitro exploration of the impact on cellular uptake, cytotoxicity, and inflammation". 2D Materials 4 2 (2017): 025065-025065.
    Publicado • 10.1088/2053-1583/aa673f
  16. Lebre, F.; Sridharan, R.; Sawkins, M.J.; Kelly, D.J.; O'Brien, F.J.; Lavelle, E.C.; Lebre, Filipa; et al. "The shape and size of hydroxyapatite particles dictate inflammatory responses following implantation". Scientific Reports 7 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85020432907&partnerID=MN8TOARS.
    Publicado • 10.1038/s41598-017-03086-0
  17. Lebre, F.; Bento, D.; Ribeiro, J.; Colaço, M.; Borchard, G.; Pedroso De Lima, M.C.P.; Borges, O.; Lebre, Filipa. "Association of chitosan and aluminium as a new adjuvant strategy for improved vaccination". International Journal of Pharmaceutics 527 1-2 (2017): 103-114. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019758926&partnerID=MN8TOARS.
    Publicado • 10.1016/j.ijpharm.2017.05.028
  18. Lebre, Filipa; Hearnden, Claire H.; Lavelle, Ed C.. "Modulation of Immune Responses by Particulate Materials". Advanced Materials 28 27 (2016): 5525-5541.
    Publicado • 10.1002/adma.201505395
  19. Lebre, F.; Borchard, G.; Faneca, H.; Pedroso de Lima, M. C.; Borges, O.. "Intranasal Administration of Novel Chitosan Nanoparticle/DNA Complexes Induces Antibody Response to Hepatitis B Surface Antigen in Mice". Molecular Pharmaceutics 13 2 (2016): 472-482.
    Publicado • 10.1021/acs.molpharmaceut.5b00707
  20. Lebre, Filipa; Borchard, Gerrit; Lima, Maria Conceição Pedroso; Borges, Olga. "Progress Towards a Needle-Free Hepatitis B Vaccine". Pharmaceutical Research 28 5 (2010): 986-1012.
    Publicado • 10.1007/s11095-010-0314-4
  21. Borges, Olga; Lebre, Filipa; Bento, Dulce; Borchard, Gerrit; Junginger, Hans E.. "Mucosal Vaccines: Recent Progress in Understanding the Natural Barriers". Pharmaceutical Research 27 2 (2009): 211-223.
    Publicado • 10.1007/s11095-009-0011-3
Livro
  1. Lebre, F.; Bento, D.; Jesus, S.; Borges, O.; Lebre, Filipa; Bento, Dulce; Jesus, Sandra; Borges, Olga. Chitosan-Based Nanoparticles as a Hepatitis B Antigen Delivery System. Academic Press: Elsevier. 2012.
    Publicado • 10.1016/B978-0-12-391858-1.00007-1
Poster em conferência
  1. Ana Ribeiro; Samantha Costa; Ana Sofia Nogueira; Lebre, Filipa; Pedro Alpuim; Alfaro, Ernesto. "P02-19 A newly developed microfluidic system designed for the cultivation of 3D epidermis and full-thickness skin, tailored for nanoparticle safety evaluation". Trabalho apresentado em EUROTOX 2024, 2024.
    https://doi.org/10.1016/j.toxlet.2024.07.289
  2. Siva Sankar; João Fernandes; Pedro Alpuim; Lebre, Filipa; Ana Ribeiro; Alfaro, Ernesto; Andrea Capasso. "Towards safer and sustainable MXene production". Trabalho apresentado em EUROTOX 2024, 2024.
    https://doi.org/10.1016/j.toxlet.2024.07.828
  3. Lebre, Filipa. "Integration of TEER sensors on skin-on-chip models for nanotoxicology studies". Trabalho apresentado em EUROoCs, 2024.
  4. Panão Costa, João; Colaço, Mariana; Félix, Paulo; Melo, Alexandra A.; Lebre, Filipa; Cruz M. T.; Alfaro-Moreno, Ernesto; Moreira J. N.; Borges, Olga. "b-glucan polymeric microparticles: innovating cancer immunotherapy through targeted antigen delivery". Trabalho apresentado em 6th Portuguese Association for Cancer Research (ASPIC) International Congress, 2024.
  5. Panão Costa, João; Colaço, Mariana; Félix, Paulo; Melo, Alexandra; Lebre, Filipa; Cruz, Maria Teresa; Alfaro-Moreno, Ernesto; Moreira, João Nuno; Borges, Olga. "ß-glucan polymeric microparticles: innovating cancer immunotherapy through targeted antigen delivery". Trabalho apresentado em 6th ASPIC International Congress, 2024.
  6. Lebre, Filipa. "Multiplexing technology: the key to unveil complex cytokine signalling networks". 2023.
Pré-impressão
  1. Di Nisio, Valentina; Li, Tianyi; Xiao, Zhijie; Papaikonomou, Kiriaki; Damdimopoulos, Anastasios; Végvári, Ákos; Lebre, Filipa; et al. "Silk-Ovarioids: Establishment and characterization of human ovarian primary cells 3D-model system". 2024. https://doi.org/10.1101/2024.07.31.606024.
    10.1101/2024.07.31.606024
  2. Lundahl, Mimmi LE; Mitermite, Morgane; Ryan, Dylan G; Case, Sarah; Williams, Niamh C; Yang, Ming; Lynch, Roisin I; et al. "Macrophage Innate Training Induced by IL-4 and IL-13 Activation Enhances OXPHOS Driven Anti-Mycobacterial Responses". 2021. http://dx.doi.org/10.1101/2021.10.12.463833.
    10.1101/2021.10.12.463833
Resumo em conferência
  1. Lebre, Filipa; Lima, Maria Conceição Pedroso; Borges, Olga. "Immunogenicity of a DNA based Hepatitis B vaccine". Trabalho apresentado em 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbon, 2014.
    Publicado
  2. Lebre, Filipa; Pedroso de Lima, M. C.; Lavelle, Ed C.; Lima, Maria Conceição Pedroso. "Vaccines: Mechanisms of chitosan nanoparticle adjuvancy partially revealed". Trabalho apresentado em XXXVIII Annual Meeting of the Portuguese Society of Immunology, Coimbra, 2014.
    Publicado
  3. Lebre, Filipa; Borchard, Gerrit; Faneca, Henrique; Lima, Maria Conceição Pedroso; Borges, Olga. "Albumin loaded chitosan nanoparticles/DNA complexes for nasal immunization". Trabalho apresentado em AAPS National Biotechnology Conference "Advancing health through innovations in biotherapeutics", San Diego, 2012.
    Publicado
  4. Jesus, Sandra; Bento, Dulce; Lebre, Filipa; Borchard, Gerrit; Borges, Olga. "Understanding the adsorption mechanism of model antigens onto chitosan-based particles". Trabalho apresentado em 38th Annual Meeting & Exposition of the Controlled Release Society, Maryland, 2011.
    Publicado
  5. Jesus, Sandra; Bento, Dulce; Lebre, Filipa; Borchard, Gerrit; Borges, Olga. "Comparison of the adsorption of different model proteins to chitosan-based particles". Trabalho apresentado em III Congress of the Portuguese Society of Pharmaceutical Sciences and IX Spanish-Portuguese Conference on Controlled Drug Delivery - New Trends in Pharmaceutical Sciences, Porto, 2011.
    Publicado
  6. Lebre, Filipa; Borchard, Gerrit; Faneca, Henrique; Lima, Maria Conceição Pedroso; Borges, Olga. "Development of chitosan nanoparticle-DNA complexes for nasal immunization against hepatitis B". Trabalho apresentado em 4th BBBB - Bled International Conference on Pharmaceutical Sciences, Bled, 2011.
    Publicado
  7. Lebre, Filipa; Borchard, Gerrit; Lima, Maria Conceição Pedroso; Borges, Olga. "Development of chitosan nanoparticle-DNA complexes for nasal immunization against hepatitis B - Preliminary results". Trabalho apresentado em Modern Vaccines/Adjuvants Formulations, Cannes, 2010.
    Publicado
  8. Borges, Olga; Lebre, Filipa; Borchard, Gerrit; Junginger, Hans E.. "Model vaccine release profile from different chitosan-based nanoparticles". Trabalho apresentado em 35th Annual Meeting & Exposition of the Controlled Release Society, New York, 2008.
    Publicado
Tese / Dissertação
  1. Lebre, Filipa Raquel Maia Fontes. "Development of chitosan-based nanoparticles for nasal immunization against hepatitis B". Doutoramento, 2017. http://hdl.handle.net/10316/41058.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/11/07 At the crossroad of cell signalling and safety Total-Nanosafe II
INL (Braga, Portugal)
2024/10/25 Excelência em Ensaios: Superando Desafios na Implementação de Boas Práticas de Laboratório Boas Práticas de Laboratório da OCDE
IPQ (Caparica, Portugal)
2024/04/11 Advancing nano-immunotoxicology using high-throughput technologies
Centro de Neurociências e Biologia Celular (Coimbra, Portugal)
2021 Immunomodulation by Nanomaterials Total-Nanosafe
International Iberian Nanotechnology Laboratory (Braga, Portugal)
2017 The Shape and Size of Hydroxyapatite Particles Dictate Inflammatory Responses Following Implantation 6th China-Europe Symposium on Biomaterials and Regenerative Medicine
(Porto, Portugal)
2016 Hydroxyapatite particle size controls the induction of inflammatory responses suggesting the need to specifically tailor particle size for the development of regenerative implants E-MRS 2016 Spring Meeting
European Materials Research Society (Lille, França)
2016 Size regulates the immune responses triggered by hydroxyapatite particles Ireland-Japan Biomaterials & Tissue Engineering Meeting
(Galway, Irlanda)
2016 Tailoring hydroxyapatite particle physicochemical properties to optimise the immunomodulatory properties of regenerative implants
(Galway, Irlanda)
2015 In vitro and in vivo model systems to explore the interaction between biomaterials and the immune system Next generation medical device research theme
(Irlanda)
2013 Nanoparticulas de quitosano: mais que um sistema de entrega? FFUC Seminar
(Coimbra, Portugal)
2013 Chitosan nanoparticles: more than a delivery system? CNC Seminar
CNC (Coimbra)
2013 Nanotechnologies in biomedicine Seminar
Faculty of Medicine in Hradec Kralove (Hradec Kralove, República Checa)
2012 Development of chitosan-based nanoparticles for nasal immunization against hepatitis B Short course "Vaccine Immunology with Exploration of Immune Response to Mucosal Vaccines
(Coimbra)
2011 Association of different immunopotentiators as promising mucosal adjuvants in future 4th International Conference on Immunopotentiators in Modern Vaccines
(Porto)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2023/09 - 2024/09 Glucan and Glucan/Chitosan Nanoparticles as Vaccine adjuvants
Coorientador
 Biotecnologia Farmacêutica (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2023/09 - 2024/09 Lactobionic acid-chitosan Nanoparticles as Delivery Systems for Curcumin
Coorientador
 Biotecnologia Farmacêutica (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2023/09 - 2024/09 Development of an immune skin-on-chip for nanocosmetic applications
Coorientador
 Engenharia Física (Mestrado)
Universidade do Minho Escola de Engenharia, Portugal
2024/05/02 - 2024/06/26 Quantificação de biomarcadores em sistemas microfluídicos
Orientador
 Bioquímica (Licenciatura/Bacharelato)
Universidade do Minho Escola de Engenharia, Portugal
2018 - 2019 Evaluation of the mechanism of trained immunity by pristine graphene
Coorientador
Trinity College of Dublin, Irlanda
2017 - 2018 Exploring the immunomodulatory properties of nanosized graphene flakes for tailoring biomedical applications
Coorientador
Trinity College of Dublin, Irlanda
2016 - 2016 Poly (D,L-Lactide-co-glycolide)-based vaccines against autoimmune diseases
Coorientador
Trinity College of Dublin, Irlanda
2015 - 2016 Immune cell activation using porous nanoparticles to target immunomodulators.
Coorientador
Trinity College of Dublin, Irlanda
2014 - 2014 The role of surface chemistry in inflammasome activation by particulate vaccine adjuvants
Coorientador
Trinity College of Dublin, Irlanda

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2024/03 - 2024/03 Good Laboratory Practices refresher course (2024/03 - 2024/03)
Outro (Outra)
 International Iberian Nanotechnology Laboratory, Portugal
2021/11/11 - 2021/11/12 TOTAL-NANOSAFE:: From Molecules to Public Health (2021/11/11 - 2022/11/12)
Conferência (Membro da Comissão Organizadora)
 International Iberian Nanotechnology Laboratory, Portugal
2011 - 2011 Vaccines and adjuvants: from antigen production to modulation of antigen-specific immune response
Simpósio (Outra)
2009 - 2009 2nd practical training course on chitosan nanoparticles as antigen delivery system for mucosal vaccination
Oficina (workshop) (Outra)

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2024/12/05 - 2024/12/05 ERA Chair Annual Meeting
Conferência
 At the Crossroads of Neuroscience and Immunology
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/11/18 - 2024/11/19 Second workshop on Harmonisation and standardisation of test methods for nano and advanced materials.
Oficina (workshop)
2024/09/08 - 2024/09/11 Congress of the European Societies of Toxicology
Conferência
 EUROTOX 2024
EUROTOX, Bélgica
2024/04/09 - 2024/04/10 Workshop AI in Grant Writing
Oficina (workshop)
 AI in Grant Writing
Global Disruption, Eslovénia
2024/01/04 - 2024/01/29 Host John Hopkins University students to work together in consulting projects using INL technologies
Outro
 Strategy Consulting
Johns Hopkins University Whiting School of Engineering, Estados Unidos
2023/11/22 - 2023/11/23 Workshop on Harmonisation and standardisation of test methods for nano and advanced materials.
Oficina (workshop)
2023/11/08 - 2023/11/09 xMAP Connect Amesterdam
Conferência
 xMAP Connect
Luminex Corporation, Estados Unidos
2023/10/27 - 2023/10/27 GLP workshop at IPQ
Oficina (workshop)
 Temas emergentes no âmbito das BLP da OCDE
Instituto Português da Qualidade, Portugal
2023/09/18 - 2023/09/20 Poster Presentation at Conference on Tools and Tests for Safer-by-Design Nanomaterials
Conferência
 Tools and Tests for Safer-by-Design Nanomaterials
International Iberian Nanotechnology Laboratory, Portugal
2023/07/18 - 2023/07/20 Hands-on training Luminex
Oficina (workshop)
Luminex Corporation, Estados Unidos
2022/06/20 - 2022/06/21 INL Summit 2022/ Transitions
Outro
International Iberian Nanotechnology Laboratory, Portugal
2021/06/20 - 2021/06/23 European Technology Platform on Nanomedicine (ETPN), 17th annual event
2018/11/26 - 2018/12/01 Transition Year Students Program. Series of workshops.
Oficina (workshop)
 TY Program
Trinity College of Dublin, Irlanda
2018/07/11 - 2018/07/12 Workshops about research project management, how you function in teams, understanding industry and communicating your science.
Oficina (workshop)
 EDGE Bootcamp
2018/02/26 - 2018/03/02 Transition Year Students Program. Series of workshops.
Oficina (workshop)
 TY Program
The University of Dublin Trinity College, Irlanda
2018 - 2018 Irish Society for Immunology Meeting
Congresso
2017 - 2017 Irish Society for Immunology Meeting
Congresso
2016 - 2016 Powder Technology Seminar
Congresso
2016 - 2016 Institute of Animal Technology Irish Branch Symposium. Dublin
Congresso
2016 - 2016 TBSI Postdoctoral Research Day
Congresso
2016 - 2016 Exploring the Microbe–Immune System Interface, Microbiology Society Irish Division and Irish Society of Immunology Focused Meeting
Congresso
2016 - 2016 E-MRS Spring Meeting
Congresso
2016 - 2016 Irish Society for Immunology Meeting
Conferência
2015/09/25 - 2015/09/25 Volunteer. EU Researchers’ Nights are public events committed to bringing researchers closer to the public. Discover Research Night
The University of Dublin Trinity College, Irlanda
2015/03/02 - 2015/03/06 Transition Year students week. Series of Workshops. Allow 15 15/16 year olds come into CRANN for a week and experience what it is like to be a scientist.
Oficina (workshop)
 TY Week
Centre for Research on Adaptive Nanostructures and Nanodevices, Irlanda
2015 - 2015 Irish Society for Immunology Meeting
Congresso
2015 - 2015 Radiation Protection Workshop
Oficina (workshop)
2015 - 2015 Science Foundation Ireland Early Career Researcher Forum
Encontro
2014 - 2014 Irish Society for Immunology Meeting
Congresso
2014 - 2014 Chemical Safety Workshop
Oficina (workshop)
2014 - 2014 Biological Safety Workshop
Congresso
2013 - 2013 XXXIX Annual Meeting of the Portuguese Society of Immunology
Congresso
2012 - 2012 AAPS National Biotechnology Conference. San Diego,
Congresso
2012 - 2012 Irish Society for Immunology Meeting
Congresso
2011 - 2011 III Congress of the Portuguese Society of Pharmaceutical Sciences and IX Spanish-Portuguese Conference on Controlled Drug Delivery
Congresso
2011 - 2011 4th BBBB - Bled International Conference on Pharmaceutical Sciences
Congresso
2010 - 2010 Modern Vaccines/Adjuvants Formulations
Congresso

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2023/12/06 Mimicking the inflamed human intestine: a multicellular in vitro model
Arguente principal
 Adriana Fernandes Pereira (Mestrado)
Universidade do Minho Escola de Ciências, Portugal

Entrevista / Programa (rádio / tv)

Programa Tema
2023/12/14 - 2023/12/14 Think Nanosafety Nanosafety

Membro de associação

Nome da associação Tipo de participação
2014 - Atual Irish Society for Immunology
2012/05 - Atual American Association of Pharmaceutical Scientists
2023/04 - 2024/04 AP Tox - Associação Portuguesa de Toxicologia Member
2013 - 2014 Sociedade Portuguesa de Imunologia
2009 - 2014 Ordem dos Farmacêuticos

Tutoria

Tópico Nome do aluno
2012 - 2012 Marcela Oliveira
2012 - 2012 Marta Sintra
2011 - 2011 Ana Lúcia Agostinho
2010 - 2010 Sandra Jesus
2009 - 2009 Sofia Valdeira
Distinções

Outra distinção

2019 SFI Industry Fellowship - 18/IF/6316
Science Foundation Ireland, Irlanda
2010 PhD fellowship - SFRH/BD/64046/2009
Portuguese Foundation for Science and Technology, Portugal
2009 Bolsa de Investigação para apoio a Doutoramento no âmbito da Patologia Infecciosa
GlaxoSmithKline Portuguese Foundation, Portugal