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Dr Henriques completed his master's degree in biomedical engineering and Biophysics in 2012 at the Faculty of Science, University of Lisbon, PT (2007-2012). During the last year of his master, he implemented the main diffusion magnetic resonance imaging (dMRI) algorithms of the large collaborative project Cambridge Centre for Ageing and Neuroscience (cam-can.org). After a brief period as a research assistant at the Institute of Biophysics and Biomedical Engineering, University of Lisbon, PT (2012-2013), Dr Henriques was awarded a fellowship from the Portuguese Foundation for Science and Technology (FCT) to pursue his PhD at the Cognition and Brain Sciences Unit (CBSU), University of Cambridge, UK (2013-2018). His PhD project was focused on exploring the potentials and limitations of advanced dMRI analysis and their application to study microstructural age-related changes (Henriques, University of Cambridge PhD thesis, 2018; Henriques et al., NIMG 2015; Henriques et al., ReScience 2017; Price et al., Nat Commun 2017; Huber et al., Dev Cogn Neurosci 2019; Bergmann et al., NMR Biomed. 2019). After his PhD, Dr Henriques was invited to join the Shamesh Lab at the Champalimaud Foundation, PT (2017-2021) as a postdoctoral fellow. There he exploited the capabilities of the pre-clinical high field scanners to validate different state-of-the-art dMRI models (Henriques et al., MRM 2019) and developed novel methods to extract unique tissue microstructural information from advanced dMRI sequences (Henriques et al., Neurosci Methods 2021). Specifically, he established the Correlation tensor MRI (CTI) - an innovative dMRI methodology that avoids the use of simplified models by characterizing microstructural tissue using different sources of non-Gaussian diffusion (Henriques et al., NIMG 2020; Henriques et al., MRM 2021). Recently, Dr Henriques was awarded a six-year postdoctoral fellowship to continue working at the Champalimaud Foundation to explore the potential of CTI to address the current needs of stroke imaging (Alves et al., NIMG 2022) and the translate it to the clinics (Novello, Henriques et al., NIMG 2022) . Dr Henriques is also an active contributor of the large-scale open-source project diffusion in python (dipy.org) which aim is to promote the reproducibility of research based on dMRI techniques (top 5 collaborator over more than 100 collaborators). During his career, Dr Henriques author in 24 main authorship in peer-reviewed publications (including 10 first-author, 2 last-author, and 6 second-author papers) and in 44 consortium papers. His work was also presented on more than 15 international conferences with a total of 64 abstracts accepted (10 of the 28 first-author abstracts were selected for oral presentations). He was also a supervisor of the Mathematical Biology lectures at the University of Cambridge (having supervised 10 undergraduate students), he supervised 2 master projects, 6 Google Summer of Code projects and he was a jury element of 2 master and 1 doctoral thesis.
Identificação

Identificação pessoal

Nome completo
Rafael Neto Henriques

Nomes de citação

  • Henriques, Rafael

Identificadores de autor

Ciência ID
731E-D1D9-090B
ORCID iD
0000-0002-3891-8189

Endereços de correio eletrónico

  • rafael.henriques@neuro.fchampalimaud.org (Profissional)

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Engenharia Médica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Italiano Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2018/10/03
Concluído
Doctor of Philosophy in Biological Sciences (Doutoramento)
Especialização em Medical Science
University of Cambridge, Reino Unido
"Advanced Methods for Diffusion MRI Data Analysis and their Application to the Healthy Ageing Brain" (TESE/DISSERTAÇÃO)
n/a
2012
Concluído
Mestrado Integrado em Engenharia Biomédica e Biofísica (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Diffusion Kurtosis Imaging of the Healthy Human Brain" (TESE/DISSERTAÇÃO)
17
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2018/10/03 - Atual Pós-doutorado (Investigação) Centro Champalimaud, Portugal
Centro Champalimaud, Portugal
2017/10/01 - 2018/10/02 Assistente de Investigação (carreira) (Investigação) Centro Champalimaud, Portugal
Centro Champalimaud, Portugal
2013/10/01 - 2017/09/30 Estagiário de Investigação (Investigação) University of Cambridge - Cognition and Brain Sciences Unit, Reino Unido
University of Cambridge - Cognition and Brain Sciences Unit, Reino Unido
2012/11/17 - 2013/09/30 Investigador (Investigação) Universidade de Lisboa Instituto de Biofísica e Engenharia Biomédica, Portugal
Universidade de Lisboa Instituto de Biofísica e Engenharia Biomédica, Portugal
2010/06/15 - 2010/09/15 Estagiário de Investigação (Investigação) University of Toronto Oral Dynamics Laboratory, Canadá
University of Toronto Oral Dynamics Laboratory, Canadá
Projetos

Bolsa

Designação Financiadores
2013/01/01 - 2017/09/30 Advanced Methods for Diffusion MRI Data Analysis and their application to the Healthy Ageing Brain
SFRH/BD/89114/2012
Bolseiro de Doutoramento
University of Cambridge - Cognition and Brain Sciences Unit, Reino Unido
Fundação para a Ciência e a Tecnologia
Concluído
2010/10/01 - 2016/03/31 Systems Cognitive Neuroscience of Healthy Ageing: Population-Representative Studies of Functional Plasticity and Neural Change
Bolseiro de Cientista Convidado
University of Cambridge, Reino Unido
Biotechnology and Biological Sciences Research Council
Concluído
2012/01/01 - 2013/09/30 Comprehensive multi-parametric analysis of the limbic system connectivity in post-traumatic epilepsy patients Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2022/06/01 - 2028/06/01 Correlation Tensor MRI: a paradigm shift for stroke management
Investigador Pós-doutorado
Fundação Champalimaud, Portugal
FCT - Fundação para a Ciência e a Tecnologia
Em curso
2017/10/01 - 2021/02/28 Sensing activity-induced cell swellings and ensuing neurotransmitter releases for in-vivo functional imaging sans hemodynamics
Investigador Pós-doutorado
Centro Champalimaud, Portugal
European Research Council
Concluído
2009/10/01 - 2010/07/31 Neuroimaging with MATLAB: MRI Brain Segmentation
Bolseiro de Integração na Investigação
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
Concluído
Produções

Publicações

Artigo em conferência
  1. Villalón-Reina, J.E.; Nir, T.M.; Nourollahimoghadam, E.; Dhinagar, N.; Jahanshad, N.; Thompson, P.M.; Henriques, Rafael. "Evaluating Fiber Orientation Dispersion Measures Computed From Single-Shell Diffusion MRI". Trabalho apresentado em 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), Sydney, 2023.
    Publicado • 10.1109/EMBC40787.2023.10340067
Artigo em revista
  1. Fouto, A.R.; Henriques, Rafael; Golub, M.; Freitas, A.C.; Ruiz-Tagle, A.; Esteves, I.; Gil-Gouveia, R.; et al. "Impact of Truncating Diffusion MRI Scans on Diffusional Kurtosis Imaging". Magnetic Resonance Materials in Physics, Biology and Medicine (2024): https://doi.org/10.1007/s10334-024-01153-y.
    Publicado
  2. Henriques, Rafael; Ianus, Andrada; Novello, Lisa; Jovicich, Jorge; Jespersen, Sune N; Shemesh, Noam. "Efficient PCA denoising of spatially correlated redundant MRI data". Imaging Neuroscience 1 (2023): 1-26. http://dx.doi.org/10.1162/imag_a_00049.
    10.1162/imag_a_00049
  3. Henriques, Rafael; Henson, Richard; Cam-CAN; Correia, Marta Morgado. "Unique information from common diffusion MRI models about white-matter differences across the human adult lifespan". Imaging Neuroscience 1 (2023): 1-25. http://dx.doi.org/10.1162/imag_a_00051.
    10.1162/imag_a_00051
  4. Sandgaard, Anders Dyhr; Kiselev, Valerij G.; Henriques, Rafael Neto; Shemesh, Noam; Jespersen, Sune Nørhøj. "Incorporating the effect of white matter microstructure in the estimation of magnetic susceptibility in ex vivo mouse brain". Magnetic Resonance in Medicine 91 2 (2023): 699-715. http://dx.doi.org/10.1002/mrm.29867.
    10.1002/mrm.29867
  5. Novello, Lisa; Henriques, Rafael Neto; Ianus, Andrada; Feiweier, Thorsten; Shemesh, Noam; Jovicich, Jorge. "In vivo Correlation Tensor MRI reveals microscopic kurtosis in the human brain on a clinical 3T scanner". NeuroImage 254 (2022): 119137. http://dx.doi.org/10.1016/j.neuroimage.2022.119137.
    10.1016/j.neuroimage.2022.119137
  6. Alves, Rita; Henriques, Rafael Neto; Kerkelä, Leevi; Chavarrías, Cristina; Jespersen, Sune N; Shemesh, Noam. "Correlation Tensor MRI deciphers underlying kurtosis sources in stroke". NeuroImage 247 (2022): 118833. http://dx.doi.org/10.1016/j.neuroimage.2021.118833.
    Publicado • 10.1016/j.neuroimage.2021.118833
  7. Simões, Rui V.; Henriques, Rafael N.; Cardoso, Beatriz M.; Fernandes, Francisca F.; Carvalho, Tânia; Shemesh, Noam. "Glucose fluxes in glycolytic and oxidative pathways detected in vivo by deuterium magnetic resonance spectroscopy reflect proliferation in mouse glioblastoma". NeuroImage: Clinical 33 (2022): 102932. http://dx.doi.org/10.1016/j.nicl.2021.102932.
    10.1016/j.nicl.2021.102932
  8. Henriques, Rafael Neto; Jespersen, Sune N.; Shemesh, Noam. "Evidence for microscopic kurtosis in neural tissue revealed by correlation tensor MRI". Magnetic Resonance in Medicine 86 6 (2021): 3111-3130. http://dx.doi.org/10.1002/mrm.28938.
    10.1002/mrm.28938
  9. Henriques, Rafael Neto; Correia, Marta M.; Marrale, Maurizio; Huber, Elizabeth; Kruper, John; Koudoro, Serge; Yeatman, Jason D.; Garyfallidis, Eleftherios; Rokem, Ariel. "Diffusional Kurtosis Imaging in the Diffusion Imaging in Python Project". Frontiers in Human Neuroscience 15 (2021): http://dx.doi.org/10.3389/fnhum.2021.675433.
    10.3389/fnhum.2021.675433
  10. Marc Golub; Rafael Neto Henriques; Rita Gouveia Nunes. "Free-water DTI estimates from single b-value data might seem plausible but must be interpreted with care". Magnetic Resonance in Medicine 85 5 (2021): 2537-2551. https://doi.org/10.1002/mrm.28599.
    10.1002/mrm.28599
  11. Henriques, Rafael; Jespersen, Sune N.; Jones, Derek K.; Veraart, Jelle. "Towards more robust and reproducible Diffusion Kurtosis Imaging". Magnetic Resonance in Medicine 86 3 (2021): 1600-1613. https://doi.org/10.1002/mrm.28730.
    Publicado
  12. Henriques, Rafael N.; Palombo, Marco; Jespersen, Sune N.; Shemesh, Noam; Lundell, Henrik; Ianus, Andrada. "Double diffusion encoding and applications for biomedical imaging". Journal of Neuroscience Methods 348 (2021): 108989. http://dx.doi.org/10.1016/j.jneumeth.2020.108989.
    10.1016/j.jneumeth.2020.108989
  13. Yon, Maxime; Bao, Qingjia; Chitrit, Odélia Jacqueline; Henriques, Rafael Neto; Shemesh, Noam; Frydman, Lucio. "High-Resolution 3D in vivo Brain Diffusion Tensor Imaging at Ultrahigh Fields: Following Maturation on Juvenile and Adult Mice". Frontiers in Neuroscience 14 (2020): http://dx.doi.org/10.3389/fnins.2020.590900.
    10.3389/fnins.2020.590900
  14. Henriques, Rafael. "Correlation tensor magnetic resonance imaging". NeuroImage 211 (2020): 116605. http://dx.doi.org/10.1016/j.neuroimage.2020.116605.
    Acesso aberto • 10.1016/j.neuroimage.2020.116605
  15. Bergmann, Ørjan; Henriques, Rafael; Westin, Carl-Fredrik; Pasternak, Ofer. "Fast and accurate initialization of the free-water imaging model parameters from multi-shell diffusion MRI". NMR in Biomedicine 33 3 (2019): http://dx.doi.org/10.1002/nbm.4219.
    10.1002/nbm.4219
  16. Kerkelä, Leevi; Henriques, Rafael Neto; Hall, Matt G.; Clark, Chris A.; Shemesh, Noam. "Validation and noise robustness assessment of microscopic anisotropy estimation with clinically feasible double diffusion encoding MRI". Magnetic Resonance in Medicine (2019): http://dx.doi.org/10.1002/mrm.28048.
    10.1002/mrm.28048
  17. Henriques, Rafael. "Microscopic anisotropy misestimation in spherical-mean single diffusion encoding MRI". Magnetic Resonance in Medicine (2019): http://dx.doi.org/10.1002/mrm.27606.
    10.1002/mrm.27606
  18. Huber, Elizabeth; Henriques, Rafael Neto; Owen, Julia P.; Rokem, Ariel; Yeatman, Jason D.. "Applying microstructural models to understand the role of white matter in cognitive development". Developmental Cognitive Neuroscience 36 (2019): 100624. http://dx.doi.org/10.1016/j.dcn.2019.100624.
    10.1016/j.dcn.2019.100624
  19. Henriques, Rafael. "Sustainable computational science: the ReScience initiative". PeerJ Computer Science (2017): http://dx.doi.org/10.7717/peerj-cs.142.
    10.7717/peerj-cs.142
  20. Henriques, Rafael. "Age-Related Delay in Visual and Auditory Evoked Responses is Mediated by White- and Gray-matter Differences". Nature Communications (2017):
    10.1038/ncomms15671
  21. Henriques, Rafael. "[Re] Optimization of a free water elimination two-compartment model for diffusion tensor imaging". ReScience (2017):
    10.5281/zenodo.495237
  22. Henriques, Rafael. "Exploring the 3D geometry of the diffusion kurtosis tensor--impact on the development of robust tractography procedures and novel biomarkers.". Neuroimage (2015):
    10.1016/j.neuroimage.2015.02.004
  23. Garyfallidis, Eleftherios; Brett, Matthew; Amirbekian, Bagrat; Rokem, Ariel; van der Walt, Stefan; Descoteaux, Maxime; Nimmo-Smith, Ian. "Dipy, a library for the analysis of diffusion MRI data". Frontiers in Neuroinformatics 8 (2014): http://dx.doi.org/10.3389/fninf.2014.00008.
    10.3389/fninf.2014.00008
  24. Henriques, Rafael. "A comparison of methods for decoupling tongue and lower lip from jaw movements in 3D articulography.". J Speech Lang Hear Res (2013):
    10.1044/1092-4388(2013/12-0016)
Resumo em conferência
  1. Henriques, Rafael; Alves, R.; Ianus, A.; Jespersen, S.N.; Shemesh N.. "Correlation Tensor MRI Directional Metrics in Stroke Improve Lesion Characterization". Trabalho apresentado em 19th European Molecular Imaging Meeting, Porto, 2024.
  2. Villalón-Reina, J.E.; Nir, T.M.; Nourollahimoghadam, E.; Jahanshad, N.; Thompson, P.M.; Henriques, Rafael. "Computing Fiber Orientation Dispersion from Single shell Diffusion MRI". Trabalho apresentado em 29th Annual Meeting of the OHBM, Montreal, 2023.
    Publicado
  3. Henriques, Rafael; Simoes, R.V.; Monteiro, S.; Ianus, A.; Carvalho, T.; Jespersen, S.N.; Shemesh N.. "Correlation Tensor Imaging Enhances Histological Differences Between Mouse Glioblastoma Subtypes". Trabalho apresentado em 2023 ISMRM & ISMRT Annual Meeting, Toronto, 2023.
    Publicado
  4. Simões, R.V.; Henriques, Rafael; Olesen, J.V.; Cardoso, B.M.; Fernandes, F.F.; Carvalho, T.; Jespersen, S.N.; Shemesh N.. "Probing Tumor Heterogeneity in Mouse Glioblastoma with Dynamic Glucose-Enhanced Deuterium Metabolic Imaging". Trabalho apresentado em 2023 ISMRM & ISMRT Annual Meeting, Toronto, 2023.
    Publicado
  5. Ianus, A., ; Palombo, M.; Simões, R.V.; Henriques, Rafael; Carvalho, T.; Shemesh N.. "Soma and Neurite Density Imaging (SANDI) characterizes microscopic differences between two glioma mouse model subtypes.". Trabalho apresentado em 2023 ISMRM & ISMRT Annual Meeting, Toronto, 2023.
    Publicado
  6. Jespersen, S.N.; Alves, R.; Olesen, J.V.; Henriques, R.N.; Shemesh N.. "Exchange-driven Microscopic Kurtosis in Correlation Tensor MRI". Trabalho apresentado em 2023 ISMRM & ISMRT Annual Meeting, Toronto, 2023.
    Publicado
  7. Alves, R.; Henriques, Rafael; Olesen, J.V.; Jespersen, S.N.; Shemesh N.. "Mapping biophysical changes in stroked tissue via the Standard Model with Exchange (SMEX) diffusion model". Trabalho apresentado em 2023 ISMRM & ISMRT Annual Meeting, Toronto, 2023.
    Publicado
  8. Slator, P.J.; Simões, R.V.; Henriques, Rafael; Carvalho, T.; Alexander, D.C.; Shemesh, N.; Ianus, A.. "Characterising glioma heterogeneity with diffusion-relaxation MRI and InSpect". Trabalho apresentado em 2023 ISMRM & ISMRT Annual Meeting, Toronto, 2023.
    Publicado
  9. Bilreiro, C.; Andrade, L.; Henriques, Rafael; Loução, N.; Shemesh, N.; Matos C.. "Diffusion tensor imaging and diffusion kurtosis imaging of the pancreas at 3 Tesla MRI - reproducibility and normal findings". Trabalho apresentado em 108th Scientific Assembly and Annual meeting Radiological Society of North America 2022, Chicago, 2022.
    Publicado
  10. Henriques, Rafael; Simões, R.V.; Monteiro, S.; Carvalho, T.; Jespersen, S.N.; Shemesh, N.. "Correlation Tensor Imaging Reveals Histologic Differences Between Mouse Glioblastoma Subtypes". Trabalho apresentado em ISMRM Workshop on Diffusion MRI: From Research to Clinic, Amsterdam, 2022.
    Publicado
  11. Alves, R.; Henriques, Rafael; Jespersen, S.N.; Shemesh, N.. "Correlation Tensor MRI Unravels Dynamic Alterations in Underlying Kurtosis Sources Along Stroke Progression". Trabalho apresentado em ISMRM Workshop on Diffusion MRI: From Research to Clinic, Amsterdam, 2022.
    Publicado
  12. Henriques, Rafael; Alves, R.,; Jespersen, S.N.; Shemesh, N.. "Three-dimensional characterization of diffusion kurtosis sources". Trabalho apresentado em 2nd Annual Meeting of the ISMRM Iberian Chapter, Lisbon, 2022.
    Publicado
  13. Alves, R.; Henriques, Rafael; Jespersen, S.N.; Shemesh, N.. "Correlation Tensor imaging Disentangles Kurtosis Sources along stroke progression". Trabalho apresentado em 2nd Annual Meeting of the ISMRM Iberian Chapter, Lisbon, 2022.
    Publicado
  14. Henriques, Rafael; Jespersen, Sune N; Shemesh, Noam. "Hybrid PCA denoising - improving PCA denoising in the presence of spatial correlations". Trabalho apresentado em Joint Annual Meeting of the ISMRM-ESMRMB, London, 2022.
    Publicado
  15. Novello, L.; Henriques, Rafael; Andrada Ianus; Feiweier, T.; Shemesh, Noam; Jovicich, J.. "First templates of human brain kurtosis sources: relevance of microscopic kurtosis from Correlation Tensor MRI at 3 Tesla". Trabalho apresentado em Joint Annual Meeting of the ISMRM-ESMRMB, London, 2022.
    Publicado
  16. Alves, Rita; Henriques, Rafael; Jespersen, S.N.; Shemesh, Noam. "Correlation Tensor MRI reveals dynamic changes in diffusion kurtosis sources along stroke progression". Trabalho apresentado em Joint Annual Meeting of the ISMRM-ESMRMB, 2022.
    Publicado
  17. Simões, R.V.; Henriques, Rafael; Cardoso, B.M.; Fernandes, F.; Carvalho, T.; Shemesh, N.. "Modulation of glucose metabolic fluxes according to tumor cell proliferation in mouse glioblastoma subtypes.". Trabalho apresentado em Joint Annual Meeting of the ISMRM-ESMRMB, London, 2022.
    Publicado
  18. Alves, R.; Henriques, Rafael; Kerkelä, L.; Chavarrías C.; Jespersen, S.N.; Shemesh, N.. "Dynamics of Diffusion Kurtosis Sources Along Stroke Progression Revealed by Correlation Tensor Imaging Diffusion". Trabalho apresentado em ISMRM Diffusion Study Group Trainee Day: 24 Hours of Diffusion Around the World (virtual meeting), 2021.
    Publicado
  19. Henriques, Rafael; Jespersen, S.N.; Shemesh N., 2021. "Evidence for microscopic kurtosis in neural tissue revealed by Correlation Tensor MRI". Trabalho apresentado em 1st Annual Meeting of the ISMRM Iberian Chapter (virtual meeting), 2021.
    Publicado
  20. Alves, R.; Henriques, Rafael; Jespersen, S.N.; Shemesh, N.. "Deciphering the underlying sources of diffusion kurtosis in focal ischemia by Correlation Tensor MRI". Trabalho apresentado em 1st Annual Meeting of the ISMRM Iberian Chapter (virtual meeting), 2021.
    Publicado
  21. Simões, R.V.; Henriques, Rafael; Cardoso, B. M.; Olesen, J.L.; Jespersen, S.N.; Shemesh, Noam. "Non-invasive assessment of glycolytic and oxidative metabolism in mouse glioma using DGE 2H-MRS. 2021". Trabalho apresentado em 29th Annual Meeting of the ISMRM (Virtual), Virtual, 2021.
    Publicado
  22. Henriques, Rafael; Correia, M.M.; Marrale, M.; Huber, Elizabeth; Kruper, J.; Koudoro, S.; Yeatman, Jason D.; Garyfallidis, E; Rokem, A.. "Diffusional Kurtosis Imaging in the Diffusion Imaging in Python Project". Trabalho apresentado em 29th Annual Meeting of the ISMRM (Virtual), 2021.
    Publicado
  23. Henriques, Rafael; Jespersen, S.N.; Jones, D.K.; Veraart, J.. "Towards more robust and reproducible Diffusion Kurtosis Imaging". Trabalho apresentado em 29th Annual Meeting of the ISMRM (Virtual), Virtual, 2021.
    Publicado
  24. Henriques, Rafael; Jespersen, S.N.; Shemesh, Noam. "Intra-compartmental kurtosis biases tensor-valued multidimensional diffusion". Trabalho apresentado em 29th Annual Meeting of the ISMRM, Virtual, 2021.
    Aceite para publicação
  25. Alves, R.; Henriques, Rafael; Jespersen, S.N.; Shemesh, Noam. "Resolving the underlying sources of diffusion kurtosis in focal ischemia by Correlation Tensor MRI.". Trabalho apresentado em 29th Annual Meeting of the ISMRM (Virtual), 2021.
    Publicado
  26. Novello, L.; Henriques, Rafael; Ianus, A.; Feiweier, T.; Shemesh, Noam; Jovicich, J.. "Human brain in vivo correlation tensor MRI on clinical 3T system". Trabalho apresentado em 29th Annual Meeting of the ISMRM (Virtual), 2021.
    Publicado
  27. Simoes, R.V.; Henriques, Rafael; Cardoso, B.M.; Carvalho, T.; Shemesh, Noam. "Glucose oxidation rate as a potential marker for GBM staging: correlation with histopathology and cell proliferation in a mouse model". Trabalho apresentado em 29th Annual Meeting of the ISMRM (Virtual), 2021.
    Publicado
  28. Alves, Rita; Henriques, Rafael; Shemesh, Noam. "Improving Stroke Detection with Correlation Tensor MRI". Trabalho apresentado em The Brain Conference “Brain Stroke: Why, how, and hope”, Federation of European Neuroscience Societies, Rungstedgaard, 2021.
  29. Alves, Rita; Henriques, Rafael; Shemesh, Noam. "Mapping Microstructural Dynamics in a Mouse Stroke Model Using Diffusion MRI". Trabalho apresentado em iMed 12.0 Conference, Lisbon, 2020.
    Publicado
  30. Henriques, Rafael; Golub, M.; Nunes, Rita. "Lesion detection using Free-Water elimination DTI - is this technique really specific to free water?". Trabalho apresentado em 28th Annual Meeting of the ISMRM (virtual), 2020.
    Publicado
  31. Henriques, Rafael; Jespersen, S.N.; Shemesh, Noam. "Correlation Tensor Imaging - resolving non-Gaussian diffusion sources of in vivo tissues". Trabalho apresentado em 28th Annual Meeting of the ISMRM (virtual), 2020.
    Publicado
  32. Henriques, Rafael; Olesen, J.L.; Jespersen, S.N.; Shemesh, Noam. "Measuring the full diffusional intra- and inter-compartmental kurtosis tensors using double diffusion encoding". Trabalho apresentado em 28th Annual Meeting of the ISMRM (virtual), 2020.
    Publicado
  33. Grilo, J.M.; Golub, M.; Reimão, S.; Henriques, Rafael; Fouto, A.; Lobo, P.P.; Fabbri, M.; Ferreira, J.J.; Nunes, R.G. "Substantia nigra changes in Parkinson’s Disease: correlation between Neuromelanin contrast and Free Water fraction". Trabalho apresentado em 28th Annual Meeting of the ISMRM (virtual), 2020.
    Publicado
  34. Henriques, Rafael; Veraart, J.. "Promoting the clinical applicability of Diffusion Kurtosis Imaging.". Trabalho apresentado em 25th Annual Meeting of the OHBM, Rome, 2019.
    Publicado
  35. Golub, M.; Henriques, Rafael; Pasternak, O.; Nunes, R.G.. "Open-source algorithm for single-shell free water DTI: potentials and limitations". Trabalho apresentado em 25th Annual Meeting of the OHBM, Rome, 2019.
    Publicado
  36. Kerkelä, Leevi; Henriques, Rafael; Hall, Matt G.; Clark, Chris A.; Shemesh, Noam. "Experimental validation and SNR analysis of a clinical double diffusion encoding sequence.". Trabalho apresentado em 27th Annual Meeting of the ISMRM, Montréal, 2019.
    Publicado
  37. Kerkelä, Leevi; Henriques, Rafael; Hall, Matt G.; Shemesh, Noam; Clark, Chris A.. "Precision of microscopic fractional anisotropy estimation using double diffusion encoding.". Trabalho apresentado em 27th Annual Meeting of the ISMRM, Montréal, 2019.
    Publicado
  38. Simões, R.V.; Caja-Galán, S.; Henriques, Rafael; Costa-Silva, B.; Shemesh, Noam. "Detection of pre-metastatic niches in perfused mouse livers by diffusion-weighted imaging at ultra-high field". Trabalho apresentado em 27th Annual Meeting of the ISMRM, Montréal, 2019.
    Publicado
  39. Yon, M.; Bao, Q.; Henriques, Rafael; Shemesh, Noam; Frydman, L.. "Spatiotemporal Encoding (SPEN) at ultra-high fields: Applications to high resolution (<100 um isotropic) in vivo mouse brain DTI". Trabalho apresentado em 27th Annual Meeting of the ISMRM, Montréal, 2019.
    Publicado
  40. Henriques, Rafael; Tax, C.M.W.; Shemesh, Noam; Veraart, J.. "Biophysical modeling of the white matter: from theory towards clinical practice". Trabalho apresentado em 27th Annual Meeting of the ISMRM, Montréal, 2019.
    Publicado
  41. Henriques, Rafael; Jespersen, S.N.; Shemesh, Noam. "The two-compartment diffusion "standard model" misestimates microscopic anisotropy in-vivo.". Trabalho apresentado em 27th Annual Meeting of the ISMRM, Montréal, 2019.
    Publicado
  42. Duarte, T.; Henriques, Rafael; Nunes, D.; Zeiler, S.R.; Krakauer, J.W.; Shemesh, Noam. "Learning-induced microstructural changes in specific layers of primary motor cortex revealed by diffusion kurtosis tensor imaging.". Trabalho apresentado em 27th Annual Meeting of the ISMRM, Montréal, 2019.
    Publicado
  43. Henriques, Rafael; Sune Jespersen; Noam Shemesh. "Correlation-tensor imaging: resolving different sources of non-Gaussian diffusion". Trabalho apresentado em 27th Annual Meeting of the ISMRM, Montréal., 2019.
    Publicado
  44. Henriques, Rafael; Correia, M.M.; Nunes, R.G.; Ferreira, H.A.. "PCA denoising using random matrix theory provides an optimal compromise between noise suppression and preservation of non-Gaussian diffusion". Trabalho apresentado em Joint Annual Meeting of the ISMRM-ESMRMB, Paris, 2018.
    Publicado
  45. Henriques, Rafael; Shemesh, Noam. "Validity Regimes of the Spherical Mean Technique". Trabalho apresentado em Joint Annual Meeting of the ISMRM-ESMRMB, Paris, 2018.
    Publicado
  46. Henriques, Rafael; Bergmann, Ø.; Rokem, A.; Pasternak, O.; Correia, M.M.. "Exploring the potentials and limitations of improved free-water elimination DTI techniques.". Trabalho apresentado em 25th Annual Meeting of the ISMRM, Honolulu, 2017.
    Publicado
  47. Henriques, Rafael; Correia, Marta. "Interpreting age-related changes based on the mean signal diffusion kurtosis". Trabalho apresentado em 25th Annual Meeting of the ISMRM, Honolulu, 2017.
    Publicado
  48. Rokem, A.; Huber, Elizabeth; Mehta, P.; Henriques, Rafael; Balazinska, M.; Yeatman, J.. "Diffusion Kurtosis Imaging for the Human Connectome Project". Trabalho apresentado em Annual Meeting of the Society for Neuroscience, San Diego, 2016.
    Publicado
  49. Henriques, Rafael; Correia, M.M.; Dell’Acqua, F.. "Tract specific measures from the fODF - a way to characterize simultaneously fiber crossing and dispersion.". Trabalho apresentado em ISMRM's Workshop on Breaking the Barriers of Diffusion MRI, Lisbon, 2016.
    Publicado
  50. Henriques, Rafael; CamCAN; Correia, M.M.. "Reducing inter and intravolume instabilities on diffusion-weighted data for ageing studies". Trabalho apresentado em 22nd Annual Meeting of the OHBM, Geneva, 2016.
    Publicado
  51. Prince, D.; Tyler, L.; Henriques, Rafael; Campbell, K.; Williams, N.; Treder, M.; Taylor, J.; CamCAN; Henson, R.. "Age-Related Delay in Visual and Auditory Evoked Responses is Mediated by White- and Gray-matter Differences.". Trabalho apresentado em 22nd Annual Meeting of the OHBM., Geneva, 2016.
    Publicado
  52. Henriques, Rafael; Correia, M.M.; Dell'Acqua, F.. "Mapping fibre dispersion and tract specific metrics in multiple fibre orientations using multi Bingham distributions". Trabalho apresentado em 24th Annual Meeting of the ISMRM, Singapore, 2016.
    Publicado
  53. Loução, R.; Elsner, K.; Nunes, R.G.; Henriques, Rafael; Correia, M.M.; Ribeiro, A.; Ferreira, H.A.. "Effects of the Number of Diffusion Directions in Diffusion Kurtosis Imaging: a Structural Connectivity Study using in vivo data.". Trabalho apresentado em 24th Annual Meeting of the ISMRM, Singapore, 2016.
    Publicado
  54. Henriques, Rafael; Lacerda, L.; Dell'Acqua, F.; Correia, M.M.. "Fiber direction estimates on diffusion MRI multi-shell protocols - comparison of the performances of DTI, DKI and Richardson-Lucy SD based tractography.". Trabalho apresentado em 32nd Annual Meeting of the ESMRMB, Edinburgh, 2015.
    Publicado
  55. Henriques, Rafael; Ferreira, H.A.; Correia, M.M.. "United Diffusion Kurtosis Imaging Toolbox". Trabalho apresentado em 32nd Annual Meeting of the ESMRMB, Edinburgh, 2015.
    Publicado
  56. Loução, R.; Nunes, R.G.; Henriques, Rafael; Correia, M.M.; Santos Ribeiro, A.; Ferreira, H.A.. "Structural Connectivity based on Diffusion Kurtosis Imaging". Trabalho apresentado em 32nd Annual Meeting of the ESMRMB, Edinburgh, 2015.
    Publicado
  57. Henriques, Rafael; Correia, M.M.; Nunes, R.G.; Ferreira, H.A.. "Resolving crossing fibers and generalizing biomarkers using the diffusion kurtosis tensor.". Trabalho apresentado em 23rd Annual Meeting of the ISMRM, Toronto, 2015.
    Publicado
  58. Henriques, Rafael; Correia, M.M.; Nunes, R.G.; Ferreira, H.A.. "Diffusion Kurtosis Imaging based Tractography". Trabalho apresentado em Joint Annual Meeting of the ISMRM-ESMRMB, Milan, 2014.
    Publicado
  59. Lacerda, L.M.; Ribeiro, A.S.; da Silva, N.A.; Henriques, Rafael; Ferreira, H.A.. "Multimodal Imaging Brain Connectivity Analysis Toolbox.". Trabalho apresentado em Joint Annual Meeting of the ISMRM-ESMRMB, Milan, 2014.
    Publicado
  60. Henriques, Rafael; Correia, M.M.; Nunes, R.G.; Ramalho, J.; Ferreira, H.A.. "Advances on Multi-Compartment Model Simulations to Interpret the 3D Geometry of Diffusion Kurtosis". Trabalho apresentado em 19th Annual Meeting of the OHBM, Seattle, 2013.
    Publicado
  61. Henriques, Rafael; Correia, M.M.; CamCAN. "Towards optimization of diffusion kurtosis imaging to study brain changes with age". Trabalho apresentado em 29th Anual Meeting of the ESMRMB, Lisbon, 2012.
    Publicado
  62. Terband, H.; Van Brenk, F.; Henriques, Rafael; van Lieshout, P.; Maassen, B.; Lowit, A.. "Speech rate strategies in younger and older adults". Trabalho apresentado em Motor Speech Conference 2012, Edegem, 2012.
    Publicado
  63. Henriques, Rafael; van Lieshout, P.. "A Comparison of Methods for Decoupling Tongues and Lips from Jaw Movements in 3D Articulography". Trabalho apresentado em International Conference on Speech Motor Control, Groningen, 2011.
    Publicado
  64. Ribeiro, A.; Fernandes, C.; Salvado, D.; Lacerda, L.; Costa, M.; Henriques, Rafael; Evans, G.; Almeida, P.; Ferreira, H.. "Combined use of Electrocardiography and Accelerometry to evaluate the physical condition of a subject". Trabalho apresentado em Conference on Electronics Telecommunications and Computers, Lisbon, 2011.
    Publicado
Tese / Dissertação
  1. Henriques, Rafael. "Advanced Methods for Diffusion MRI Data Analysis and their Application to the Healthy Ageing Brain". Doutoramento, University of Cambridge - Cognition and Brain Sciences Unit, 2018. https://www.repository.cam.ac.uk/handle/1810/281993.
  2. Henriques, Rafael. "Diffusion Kurtosis Imaging of the Healthy Human Brain". Mestrado, Universidade de Lisboa Faculdade de Ciências, 2012. https://core.ac.uk/download/pdf/12428129.pdf.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/11/07 Diffusion Imaging in Python (DIPY) and its contributions to open and reproducible research MRI together workshop
European Society for Magnetic Resonance in Medicine and Biology
2022/06/07 Diffusion Artefacts and pre-processing Joint Annual Meeting of the ISMRM-ESMRMB
International Society for Magnetic Resonance in Medicine (London, Reino Unido)
2022/01/30 Correlation Tensor MRI - resolving kurtosis sources in health and disease. Microstructural imageries series
New York University (NYU) school of medicine (New York, Estados Unidos)
2021/12/16 Ressonância magnética por contraste de difusão. Biomedical Engineering and Biophysics Seminars
Faculty of Science University of Lisbon (Lisboa, Portugal)
2021/06/10 Diffusion MRI - free water imaging and beyond. CES Weekly talk series.
Clinical & Experimental Sciences (CES) Division. Southampton General Hospital ( Southampton, Reino Unido)
2021/04/04 Correlation Tensor Imaging. UCL Quantitative MRI interest group
University College London (London, Reino Unido)
2021/03/15 Diffusion Kurtosis Imaging & Microstructural Models Annual Dipy workshop (Virtual edition).
Indiana University, Bloomington, USA
2020/11/24 Diffusion MRI with Python Pybrain workshop
Cognition and Brain Sciences Unit, University of Cambridge, UK (Virtual)
2020/08/08 Correlation Tensor Imaging - resolving non-Gaussian diffusion sources of in vivo tissues 28th Annual Meeting of the ISMRM
ISMRM (Paris, França)
2020/08/08 Measuring the full diffusional intra- and inter-compartmental kurtosis tensors using double diffusion encoding 28th Annual Meeting of the ISMRM
ISMRM (Paris, França)
2019/10/15 Correlation Tensor Imaging Clinical Imaging Sciences Centre (CISC) Seminar section
Clinical Imaging Sciences Centre (CISC) (Brighton, Reino Unido)
2019/05/13 Biophysical modeling of the white matter: from theory towards clinical practice ISMRM 27th Annual Meeting & Exhibition
ISMRM (Montreal)
2019/05/11 The two-compartment diffusion "standard model" misestimates microscopic anisotropy in-vivo ISMRM 27th Annual Meeting & Exhibition
ISMRM (Montreal, Canadá)
2019/03/16 Diffusion Representation Techniques and Microstructural Models Dipy workshop
Indiana University, Bloomington, USA (Bloomington, Estados Unidos)
2018/04/24 Validity Regimes of the Spherical Mean Technique Joint Annual Meeting ISMRM-ESMRMB 2018
ISMRM-ESMRMB (Paris, França)
2017/04/27 Interpreting age-related changes based on the mean signal diffusion kurtosis ISMRM 25th Annual Meeting & Exhibition
ISMRM (Honolulu, Estados Unidos)
2015/10/03 Fiber direction estimates on diffusion MRI multi-shell protocols -comparison of the performances of DTI, DKI and Richardson-Lucy SD based tractography ESMRMB 2015, 32nd Annual Scientific Meeting
ESMRMB (Edinburgh, Reino Unido)
2015/06/05 Resolving crossing fibers and generalizing biomarkers using the diffusion kurtosis tensor ISMRM 23rd Annual Meeting & Exhibition
ISMRM (Toronto, Canadá)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2020/01/26 - 2021/02/23 Diffusion Microscopic Anisotropy Estimation in the Brain
Orientador
Biomedical Engineering (Mestrado)
NOVA School of Science and Technology, Portugal
2018/02/01 - 2018/11/27 Implementation of an algorithm for estimating free-water fraction in Diffusion-Weighted Magnetic Resonance Imaging
Coorientador
Instituto Superior Técnico Departamento de Física, Portugal

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2020/06/12 Combined brain language connectivity and intraoperativeneurophysiologic techniques in awake craniotomy for eloquent-area brain tumor resection
Arguente
João Carlos Leote Rebocho (Doutoramento)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
2019/02/18 Integration of Multi-shell Diffusion Imaging derived Metrics in Tractography Reconstructions of Clinical Data
Arguente principal
Joana Rita Simões Guido (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
2018/11/12 Identification of brain connectivity disruptions due to thalamic lesions in early development using Diffusion-Weighted MRI
Arguente principal
Ana Rita Veiga de Oliveira (Mestrado)
Instituto Superior Técnico Departamento de Física, Portugal

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2021/07/31 Interviewed for the Portuguese National Newspaper Público Público

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2023/02/01 - 2024/12/31 Official Google Summer of Code (GSoC) administration. Admin of the "Diffusion in Python" sub-organization of the "Python" organization of the Google Summer of Code (GSoC) program which objective is to support new contributors (typically master or PhD students) into open-source software development by financing 3-months projects.
Membro
Google Inc, Estados Unidos
2020/08/15 - 2022/05/15 I was the elected trainee representative for the Diffusion Study Group (DSG) of the prestigious International Society for Magnetic Resonance in Medicine (ISMRM). The DSG has the mission to facilitate the technological development, evaluation, and clinical application of diffusion MRI.
Membro
International Society for Magnetic Resonance in Medicine, Estados Unidos

Tutoria

Tópico Nome do aluno
2023/06/01 - 2023/09/30 DIPY: Correlation Tensor Magnetic Resonance Imaging Shilpi Prasad
2023/06/01 - 2023/09/30 Generative Synthetic MRI Data Vara Lakshmi
2022/06/01 - 2022/09/30 Improving GPU-accelerated Monte Carlo simulations in Disimpy Joel Hurtado Moreno
2022/06/01 - 2022/09/30 Implementation of White Matter Substrates in Disimpy Renata Cruz
2013/10/15 - 2015/06/15 Mathematical biology - Natural Sciences Tripos - University of Cambridge, UK 10 Students
Distinções

Prémio

2022 Individual Call to Scientific Employment Stimulus (2021.01773.CEECIND)
FCT - Fundação para a Ciência e a Tecnologia, Portugal
2021 Best pre-clinical oral presentation award
1st annual meeting of the ISMRM-IBERIAN chapter , Estados Unidos
2020 Magna Cum Laude Award for the oral presentation: Measuring the full diffusional intra- and inter-compartmental kurtosis tensors using double diffusion encoding.
International Society for Magnetic Resonance in Medicine, Estados Unidos
2020 Summa Cum Laude Merit Award for the oral presentation: Correlation Tensor Imaging - resolving non-Gaussian diffusion sources of in vivo tissues.
International Society for Magnetic Resonance in Medicine, Estados Unidos
2017 Travel grant for a two weeks project at the University of Washington eScience Institute
International Neuroinformatics Coordinating Facility, Suécia
2017 Magna Cum Laude Award for the oral presentation: Interpreting age-related changes based on the mean signal diffusion kurtosis.
International Society for Magnetic Resonance in Medicine, Estados Unidos
2016 Travel Grant to present a poster at ISMRM Workshop on "Breaking the Barries of Diffusion MRI"
Guarantors Of Brain, Reino Unido
2015 Google Summer of Code 2015 participation award
Google Inc, Estados Unidos
2013 PhD research grant (SFRH/BD/89114/2012)
FCT - Fundação para a Ciência e a Tecnologia, Portugal
2009 Integration into Research Grant
FCT - Fundação para a Ciência e a Tecnologia, Portugal

Outra distinção

2022 Reproducibility Research Honourable mention
International Society for Magnetic Resonance in Medicine, Estados Unidos
2022 NeuroImage Cover featuring the original article "In vivo Correlation Tensor MRI reveals microscopic kurtosis in the human brain on a clinical 3T scanner"
Elsevier BV, Países Baixos
2022 Top 10% most downloaded paper during its first 12 months for the original article “Towards more robust and reproducible Diffusion Kurtosis Imaging” submitted at the Journal “Magnetic Resonance in Medicine"
J B Wiley Co, Estados Unidos
2020 Top 10% most downloaded paper during its first 12 months for the original article “Microscopic anisotropy misestimation in spherical-mean Single Diffusion Encoding MRI.” submitted at the Journal “Magnetic Resonance in medicine”
J B Wiley Co, Estados Unidos
2017 25th ISMRM annual meeting Trainee Stipend Award
International Society for Magnetic Resonance in Medicine, Estados Unidos
2017 1st Place for Best Research Project Presentation at the diffusion study group. Poster presentation: Exploring the potentials and limitations of improved free-water elimination DTI techniques.
International Society for Magnetic Resonance in Medicine, Estados Unidos
2017 Marie Sklodowska-Curie Actions Seal of Excellence for the Postdoctoral Fellowship proposal titled “NAPALM: Mapping specific aspects of neuroplasticity using advanced MRI sequences and ultra-field MRI”
European Commission Marie Sklodowska-Curie Actions, Bélgica
2016 24th ISMRM annual meeting Trainee Stipend Award
International Society for Magnetic Resonance in Medicine, Estados Unidos
2015 Certificate of Merit for presenting the poster "United Diffusion Kurtosis Imaging (UDKI) Toolbox"
European Society for Magnetic Resonance in Medicine and Biology, Bélgica
2011 Erasmus student mobility for placements scholarship
European Commission, Bélgica
2009 One of the best 40 first year student (2007/2008) of the Faculty of Science, University of Lisbon
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal