Anabela Pinto Rolo (8710-919C-E2A5)

Curriculum Vitae

Anabela Pinto Rolo

Anabela Rolo, Ph.D. is an Associate Professor in the Department of Life Sciences, University of Coimbra, Portugal and Investigator at the Center for Neurosciences and Cell Biology from the same University. Her research interests are focused on the pathophysiological mechanisms of mitochondrial dysfunction and human health, particularly on the signaling pathways that regulate mitochondrial turnover expertise in metabolic diseases. Anabela Rolo has published over 97 papers with an h factor of 33 and 62,67 citations per paper on average. She is currently on the Editorial Board for the journals Toxicology and Applied Pharmacology and Toxicology Mechanisms and Methods. Anabela Rolo is supervisor of one ongoing PhD, has co-supervised 5 PhD theses, supervised 5 MSc dissertations and co-supervised 13. Participates and/or participated as researcher in 12 projects. She was trained as a Biologist at the University of Coimbra, Portugal from where she also received her Ph.D. and postdoctoral training in Biochemical Toxicology at the University of Minnesota, Duluth, USA and Cellular Biology at the University of California, Davis, USA.

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Identificação

Identificação pessoal

Nome completo: Anabela Pinto Rolo

Nomes de citação

Rolo AP
Rolo A

Identificadores de autor

Ciência ID: 8710-919C-E2A5
ORCID iD: 0000-0003-3535-9630

Endereços de correio eletrónico

anpiro@ci.uc.pt (Profissional)

Domínios de atuação

Ciências Naturais - Ciências Biológicas - Biologia Celular

Formação

	Grau	Classificação
2003 Concluído	Doutoramento em Biologia Celular (Doutoramento) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Cholestasis and hepatic ischemia: bile acids therapy. Cellular mechanisms with relevance to mitochondrial function." (TESE/DISSERTAÇÃO)	Unanimidade com louvor e distinção
1999/07/31 Concluído	Licenciatura em Biologia (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "na" (TESE/DISSERTAÇÃO)	18 valores

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2009 - 2013	Investigador Auxiliar (carreira) (Investigação)	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

2006 - 2009	Pós-doutorado (Investigação)	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

2003 - 2006	Pós-doutorado (Investigação)	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Docência no Ensino Superior

	Categoria Profissional Instituição de acolhimento	Empregador
2015 - 2022/12/31	Professor Auxiliar (Docente Universitário)	Universidade de Coimbra, Portugal

2013 - 2015	Professor Auxiliar (Docente Universitário)	Universidade de Aveiro, Portugal
	Universidade de Aveiro Departamento de Biologia, Portugal
2007 - 2013	Professor Auxiliar Convidado (Docente Universitário)	Universidade de Aveiro, Portugal
	Universidade de Aveiro Departamento de Biologia, Portugal
1998 - 1999	Assistente (Docente Universitário)	Universidade de Coimbra, Portugal
	Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Projetos

Projeto

	Designação	Financiadores
2018 - Atual	FRUITIFY - Use of blueberry juice as a nutraceutical strategy targeting gut dysbiosis to prevent the progression from prediabetes to diabetes PTDC/SAU-NUT/31712/2017 Investigador Instituto Biomédico de Investigação da Luz e da Imagem, Portugal	Concluído
2016 - 2019	EXERCISING THE FUTURE: VOLUNTARY EXERCISE DURING GESTATIONAL DIABETES AS A MEANS TO IMPROVE MITOCHONDRIAL FUNCTION IN THE OFFSPRING PTDC/DTP-DES/1082/2014 Investigador	Fundação para a Ciência e a Tecnologia Concluído
2016 - 2019	THE INTERPLAY BETWEEN CAMP AND SIRTUINS AS A NEXUS OF MITOCHONDRIAL AND METABOLIC CONTROL PTDC/BIM-MEC/6911/2014 Investigador Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2013 - 2014	Chronic effects of silver nanoparticles (AgNPs) on rat liver, kidney and heart mitochondrial function NA Investigador	Concluído
2010 - 2013	LONG-TERM BENEFICIAL INFLUENCE OF EARLY METABOLIC CONTROL: PREVENTION OF HYPERGLYCEMIC MEMORY TROUGH STIMULATION OF BIOENERGETICS PTDC/QUIBIQ/ 103514/2008 Investigador Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2010 - 2013	Mechanisms underlying the effects of nitric oxide on neural stem cell proliferation in brain injury PTDC/SAU-NEU/102612/2008 Investigador Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2011 - 2012	ABILITY OF A MITOCHONDRIAL IMPROVER, BERBERINE, TO ATTENUATE PARKINSON ´S DISEASE NA Investigador	Concluído
2008 - 2010	MODULATION OF METABOLIC PATHWAYS INVOLVED IN MITOCHONDRIAL OXIDATIVE STRESS CAUSED BY HYPERGLYCEMIC CONDITIONS:RELEVANCE FOR DIABETES PREVENTION PTDC/QUIM/72826/2006 Investigador Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2007 - 2010	DISTURBANCE OF THE PHYSIOLOGIC PATHWAYS AND MOLECULAR MECHANISMS REGULATING ENERGY HOMEOSTASIS IN OBESITY AND METABOLIC SYNDROME: SEARCHING NEW STRATEGIES AND THERAPEUTIC TARGETS PTDC/SAU-OSM/72443/2006 Investigador Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2007 - 2008	IN VITRO ASSESSMENT OF SILVER NANOPARTICLES TOXICITY IN HEPATIC MITOCHONDRIAL FUNCTION FA8655-07- 1-3047 Investigador	Concluído
2007 - 2007	13C NMR ISOTOPOMER ANALYSIS OF INTERMEDIARY METABOLISM IN A ADRIAMYCIN HEART FAILURE MODEL 1774-602-6050-7901 Investigador	National Heart Lung and Blood Institute Concluído
2002 - 2005	COLESTASE E ESTEATOSE HEPÁTICA: TERAPIA COM ÁCIDOS BILIARES. MECANISMOS CELULARES COM RELEVÂNCIA NA FUNÇÃO MITOCONDRIAL POCTI/CBO/42486/2001 Investigador Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluído

Produções

Publicações

Artigo em revista	Machado, Ivo F.; Miranda, Raul G.; Dorta, Daniel J.; Rolo, Anabela P.; Palmeira, Carlos M.. "Targeting Oxidative Stress with Polyphenols to Fight Liver Diseases". Antioxidants 12 6 (2023): 1212. http://dx.doi.org/10.3390/antiox12061212. 10.3390/antiox12061212 Lopes, Cátia R.; Silva, Joana S.; Santos, Joana; Rodrigues, Matilde S.; Madeira, Daniela; Oliveira, Andreia; Moreira-de-Sá, Ana; et al. "Downregulation of Sirtuin 1 Does Not Account for the Impaired Long-Term Potentiation in the Prefrontal Cortex of Female APPswe/PS1dE9 Mice Modelling Alzheimer’s Disease". International Journal of Molecular Sciences 24 8 (2023): 6968. http://dx.doi.org/10.3390/ijms24086968. 10.3390/ijms24086968 Machado, Ivo F.; Palmeira, Carlos M.; Rolo, Anabela P.. "Preservation of Mitochondrial Health in Liver Ischemia/Reperfusion Injury". Biomedicines 11 3 (2023): 948. http://dx.doi.org/10.3390/biomedicines11030948. 10.3390/biomedicines11030948 Teodoro, João S.; Da Silva, Rui T.; Machado, Ivo F.; Panisello-Roselló, Arnau; Roselló-Catafau, Joan; Rolo, Anabela P.; Palmeira, Carlos M.. "Shaping of Hepatic Ischemia/Reperfusion Events: The Crucial Role of Mitochondria". Cells 11 4 (2022): 688. http://dx.doi.org/10.3390/cells11040688. 10.3390/cells11040688 Amorim, João A.; Coppotelli, Giuseppe; Rolo, Anabela P.; Palmeira, Carlos M.; Ross, Jaime M.; Sinclair, David A.. "Mitochondrial and metabolic dysfunction in ageing and age-related diseases". Nature Reviews Endocrinology (2022): http://dx.doi.org/10.1038/s41574-021-00626-7. 10.1038/s41574-021-00626-7 Teixeira da Silva, Rui; Machado, Ivo F.; Teodoro, João S.; Panisello-Roselló, Arnau; Roselló-Catafau, Joan; Rolo, Anabela P.; Palmeira, Carlos M.. "PEG35 as a Preconditioning Agent against Hypoxia/Reoxygenation Injury". International Journal of Molecular Sciences 23 3 (2022): 1156. http://dx.doi.org/10.3390/ijms23031156. 10.3390/ijms23031156 Nunes, Sara; Viana, Sofia D.; Preguiça, Inês; Alves, André; Fernandes, Rosa; Teodoro, João S.; Matos, Patrícia; et al. "Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics". Nutrients 13 12 (2021): 4192. http://dx.doi.org/10.3390/nu13124192. 10.3390/nu13124192 Teodoro, João S.; Machado, Ivo F.; Castela, Ana C.; Amorim, João A.; Jarak, Ivana; Carvalho, Rui A.; Palmeira, Carlos M.; Rolo, Anabela P.. "Chenodeoxycholic Acid Has Non-Thermogenic, Mitodynamic Anti-Obesity Effects in an In Vitro CRISPR/Cas9 Model of Bile Acid Receptor TGR5 Knockdown". International Journal of Molecular Sciences 22 21 (2021): 11738. http://dx.doi.org/10.3390/ijms222111738. 10.3390/ijms222111738 Piochi, Luiz F.; Machado, Ivo F.; Palmeira, Carlos M.; Rolo, Anabela P.. "Sestrin2 and mitochondrial quality control: Potential impact in myogenic differentiation". Ageing Research Reviews 67 (2021): 101309. http://dx.doi.org/10.1016/j.arr.2021.101309. Publicado • 10.1016/j.arr.2021.101309 Oliveira, Raúl P.; Machado, Ivo F.; Palmeira, Carlos M.; Rolo, Anabela P.. "The potential role of sestrin 2 in liver regeneration". Free Radical Biology and Medicine 163 (2021): 255-267. http://dx.doi.org/10.1016/j.freeradbiomed.2020.12.027. 10.1016/j.freeradbiomed.2020.12.027 Machado, Ivo F.; Teodoro, João S.; Castela, Ana C.; Palmeira, Carlos M.; Rolo, Anabela P.. "miR-378a-3p Participates in Metformin’s Mechanism of Action on C2C12 Cells under Hyperglycemia". International Journal of Molecular Sciences 22 2 (2021): 541. http://dx.doi.org/10.3390/ijms22020541. 10.3390/ijms22020541 Nunes, Sara; Viana, Sofia D.; Preguiça, Inês; Alves, André; Fernandes, Rosa; Teodoro, João S.; Figueirinha, Artur; et al. "Blueberry Consumption Challenges Hepatic Mitochondrial Bioenergetics and Elicits Transcriptomics Reprogramming in Healthy Wistar Rats". Pharmaceutics 12 11 (2020): 1094. http://dx.doi.org/10.3390/pharmaceutics12111094. 10.3390/pharmaceutics12111094 Teodoro, João S.; Amorim, João A.; Machado, Ivo F.; Castela, Ana C.; Steegborn, Clemens; Sinclair, David A.; Rolo, Anabela P.; Palmeira, Carlos M.. "The Soluble Adenylyl Cyclase Inhibitor LRE1 Prevents Hepatic Ischemia/Reperfusion Damage Through Improvement of Mitochondrial Function". International Journal of Molecular Sciences 21 14 (2020): 4896. http://dx.doi.org/10.3390/ijms21144896. 10.3390/ijms21144896 Teodoro, João S.; Silva, Rui; Aguiar, António; Sobral, Abílio J. F. N.; Rolo, Anabela P.; Palmeira, Carlos M.. "Exploration of the cellular effects of the high-dose, long-term exposure to coffee roasting product furan and its by-product cis-2-butene-1,4-dial on human and rat hepatocytes". Toxicology Mechanisms and Methods 30 7 (2020): 536-545. http://dx.doi.org/10.1080/15376516.2020.1780361. 10.1080/15376516.2020.1780361 Makrecka-Kuka, Marina; Liepinsh, Edgars; Murray, Andrew J.; Lemieux, Hélène; Dambrova, Maija; Tepp, Kersti; Puurand, Marju; et al. "Altered mitochondrial metabolism in the insulin-resistant heart". Acta Physiologica 228 3 (2020): http://dx.doi.org/10.1111/apha.13430. 10.1111/apha.13430 Gomes P; Viana SD; Nunes S; Rolo AP; Palmeira CM; Reis F. "The yin and yang faces of the mitochondrial deacetylase sirtuin 3 in age-related disorders.". Ageing research reviews (2020): http://europepmc.org/abstract/med/31740222. 10.1016/j.arr.2019.100983 Milton-Laskibar, I.; Aguirre, L.; Gómez-Zorita, S.; Rolo, A. P.; Portillo, M. P.. "The influence of dietary conditions in the effects of resveratrol on hepatic steatosis". Food & Function 11 11 (2020): 9432-9444. http://dx.doi.org/10.1039/d0fo01943g. 10.1039/d0fo01943g Machado, Ivo F.; Teodoro, João S.; Palmeira, Carlos M.; Rolo, Anabela P.; Machado IF; Teodoro JS; Palmeira CM; Rolo AP. "miR-378a: a new emerging microRNA in metabolism". Cellular and molecular life sciences : CMLS (2020): http://europepmc.org/abstract/med/31748917. Publicado • 10.1007/s00018-019-03375-z Martins RM; Teodoro JS; Furtado E; Oliveira RC; Tralhão JG; Rolo AP; Palmeira CM. "Mild hypothermia during the reperfusion phase protects mitochondrial bioenergetics against ischemia-reperfusion injury in an animal model of ex-vivo liver transplantation-an experimental study.". International journal of medical sciences (2019): http://europepmc.org/abstract/med/31588197. 10.7150/ijms.34617 Palmeira CM; Teodoro JS; Amorim JA; Steegborn C; Sinclair DA; Rolo AP. "Mitohormesis and metabolic health: The interplay between ROS, cAMP and sirtuins.". Free radical biology & medicine (2019): http://europepmc.org/abstract/med/31349039. 10.1016/j.freeradbiomed.2019.07.017 Martins RM; Teodoro JS; Furtado E; Rolo AP; Palmeira CM; Tralhão JG. "Evaluation of bioenergetic and mitochondrial function in liver transplantation.". Clinical and molecular hepatology (2019): http://europepmc.org/abstract/med/30897898. 10.3350/cmh.2018.0087 Panisello-Roselló A; Alva N; Flores M; Lopez A; Castro Benítez C; Folch-Puy E; Rolo A; et al. "Aldehyde Dehydrogenase 2 (ALDH2) in Rat Fatty Liver Cold Ischemia Injury.". International Journal of Molecular Sciences (2018): http://europepmc.org/abstract/med/30131474. 10.3390/ijms19092479 Panisello-Roselló A; Lopez A; Folch-Puy E; Carbonell T; Rolo A; Palmeira C; Adam R; Net M; Roselló-Catafau J. "Role of aldehyde dehydrogenase 2 in ischemia reperfusion injury: An update.". World journal of gastroenterology (2018): http://europepmc.org/abstract/med/30038465. 10.3748/wjg.v24.i27.2984 Pereira LC; Cabral Miranda LF; Franco-Bernardes MF; Tasso MJ; Duarte FV; Inácio Varela AT; Rolo AP; Marques Palmeira CM; Dorta DJ. "Mitochondrial damage and apoptosis: Key features in BDE-153-induced hepatotoxicity.". Chemico-biological interactions (2018): http://europepmc.org/abstract/med/29935161. 10.1016/j.cbi.2018.06.021 Teodoro JS; Varela AT; Duarte FV; Gomes AP; Palmeira CM; Rolo AP. "Indirubin and NAD+ prevent mitochondrial ischaemia/reperfusion damage in fatty livers.". European journal of clinical investigation (2018): http://europepmc.org/abstract/med/29603199. 10.1111/eci.12932 Martins RM; Teodoro JS; Furtado E; Rolo AP; Palmeira CM; Tralhão JG. "Recent insights into mitochondrial targeting strategies in liver transplantation.". International journal of medical sciences (2018): http://europepmc.org/abstract/med/29483816. 10.7150/ijms.22891 Teodoro JS; Nunes S; Rolo AP; Reis F; Palmeira CM. "Therapeutic Options Targeting Oxidative Stress, Mitochondrial Dysfunction and Inflammation to Hinder the Progression of Vascular Complications of Diabetes.". Frontiers in physiology (2018): http://europepmc.org/abstract/med/30705633. 10.3389/fphys.2018.01857 Egea, J.; Fabregat, I.; Frapart, Y.M.; Ghezzi, P.; Görlach, A.; Kietzmann, T.; Kubaichuk, K.; et al. "Corrigendum to “European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)”". Redox Biology 14 (2018): 694-696. http://www.scopus.com/inward/record.url?eid=2-s2.0-85032289195&partnerID=MN8TOARS. 10.1016/j.redox.2017.10.001 Martins, R.M.; Rolo, A.P.; Teodoro, J.S.; Furtado, E.; Oliveira, R.C.; Tralhão, J.G.; Palmeira, C.M.. "Addition of berberine to preservation solution in an animal model of ex vivo liver transplant preserves mitochondrial function and bioenergetics from the damage induced by ischemia/reperfusion". International Journal of Molecular Sciences 19 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85040938454&partnerID=MN8TOARS. 10.3390/ijms19010284 Panisello-Roselló, A.; Verde, E.; Lopez, A.; Flores, M.; Folch-Puy, E.; Rolo, A.; Palmeira, C.; et al. "Cytoprotective mechanisms in fatty liver preservation against cold ischemia injury: A comparison between IGL-1 and HTK". International Journal of Molecular Sciences 19 2 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85041019515&partnerID=MN8TOARS. 10.3390/ijms19020348 Alexandrino H; Rolo A; Teodoro JS; Donato H; Martins R; Serôdio M; Martins M; et al. "Bioenergetic adaptations of the human liver in the ALPPS procedure - how liver regeneration correlates with mitochondrial energy status.". HPB : The Official Journal of the International Hepato Pancreato Biliary Association (2017): http://europepmc.org/abstract/med/28941575. 10.1016/j.hpb.2017.08.005 Egea, Javier; Fabregat, Isabel; Frapart, Yves M.; Ghezzi, Pietro; Görlach, Agnes; Kietzmann, Thomas; Kubaichuk, Kateryna; et al. "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)". Redox Biology 13 (2017): 94-162. http://dx.doi.org/10.1016/j.redox.2017.05.007. 10.1016/j.redox.2017.05.007 Milton-Laskibar I; Aguirre L; Fernández-Quintela A; Rolo AP; Soeiro Teodoro J; Palmeira CM; Portillo MP. "Lack of Additive Effects of Resveratrol and Energy Restriction in the Treatment of Hepatic Steatosis in Rats.". Nutrients (2017): http://europepmc.org/abstract/med/28696376. 10.3390/nu9070737 Duarte FV; Amorim JA; Varela AT; Teodoro JS; Gomes AP; Cunha RA; Palmeira CM; Rolo AP. "Adenosine receptors: regulatory players in the preservation of mitochondrial function induced by ischemic preconditioning of rat liver.". (2017): http://europepmc.org/abstract/med/27848069. 10.1007/s11302-016-9548-x Pereira LC; Duarte FV; Varela ATIF; Rolo AP; Palmeira CMM; Dorta DJ. "Exposure to BDE-153 induces autophagy in HepG2 cells.". (2017): http://europepmc.org/abstract/med/28396260. 10.1016/j.tiv.2017.04.005 Zaouali MA; Panisello A; Lopez A; Castro C; Folch E; Carbonell T; Rolo A; et al. "GSK3ß and VDAC Involvement in ER Stress and Apoptosis Modulation during Orthotopic Liver Transplantation.". (2017): http://europepmc.org/abstract/med/28282906. 10.3390/ijms18030591 Pereira LC; Duarte FV; Varela AT; Rolo AP; Palmeira CM; Dorta DJ. "An autophagic process is activated in HepG2 cells to mediate BDE-100-induced toxicity.". (2017): http://europepmc.org/abstract/med/27234317. 10.1016/j.tox.2016.05.022 Amorim, J.A.; Canas, P.M.; Tomé, A.R.; Rolo, A.P.; Agostinho, P.; Palmeira, C.M.; Cunha, R.A.; et al. "Mitochondria in Excitatory and Inhibitory Synapses have Similar Susceptibility to Amyloid-ß Peptides Modeling Alzheimer's Disease". Journal of Alzheimer's Disease 60 2 (2017): 525-536. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029613373&partnerID=MN8TOARS. 10.3233/JAD-170356 Rossetti A; Togliatto G; Rolo AP; Teodoro JS; Granata R; Ghigo E; Columbano A; Palmeira CM; Brizzi MF. "Unacylated ghrelin prevents mitochondrial dysfunction in a model of ischemia/reperfusion liver injury.". Cell death discovery (2017): http://europepmc.org/abstract/med/29354291. 10.1038/cddiscovery.2017.77 Teodoro JS; Gomes AP; Varela AT; Duarte FV; Rolo AP; Palmeira CM. "Hepatic and skeletal muscle mitochondrial toxicity of chitosan oligosaccharides of normal and diabetic rats.". (2016): http://europepmc.org/abstract/med/27790925. 10.1080/15376516.2016.1222643 Teodoro JS; Rolo AP; Jarak I; Palmeira CM; Carvalho RA. "The bile acid chenodeoxycholic acid directly modulates metabolic pathways in white adipose tissue in vitro: insight into how bile acids decrease obesity.". (2016): http://europepmc.org/abstract/med/27488269. 10.1002/nbm.3583 Alexandrino H; Varela AT; Teodoro JS; Martins MA; Rolo AP; Tralhão JG; Palmeira CM; Castro E Sousa F. "Mitochondrial bioenergetics and posthepatectomy liver dysfunction.". (2016): http://europepmc.org/abstract/med/27138992. 10.1111/eci.12639 Teodoro JS; Silva R; Varela AT; Duarte FV; Rolo AP; Hussain S; Palmeira CM. "Low-dose, subchronic exposure to silver nanoparticles causes mitochondrial alterations in Sprague-Dawley rats.". (2016): http://europepmc.org/abstract/med/27171910. 10.2217/nnm-2016-0049 Görlach A; Dimova EY; Petry A; Martínez-Ruiz A; Hernansanz-Agustín P; Rolo AP; Palmeira CM; Kietzmann T. "Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved?". (2015): http://europepmc.org/abstract/med/26339717. 10.1016/j.redox.2015.08.016 Pantazi E; Zaouali MA; Bejaoui M; Folch-Puy E; Ben Abdennebi H; Varela AT; Rolo AP; Palmeira CM; Roselló-Catafau J. "Sirtuin 1 in rat orthotopic liver transplantation: an IGL-1 preservation solution approach.". (2015): http://europepmc.org/abstract/med/25684941. 10.3748/wjg.v21.i6.1765 Pantazi, E.; Bejaoui, M.; Zaouali, M.A.; Folch-Puy, E.; Rolo, A.P.; Panisello, A.; Palmeira, C.M.; Roselló-Catafau, J.. "Losartan activates sirtuin 1 in rat reduced-size orthotopic liver transplantation". World Journal of Gastroenterology 21 26 (2015): 8021-8031. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937022268&partnerID=MN8TOARS. 10.3748/wjg.v21.i26.8021 Duarte FV; Amorim JA; Palmeira CM; Rolo AP. "Regulation of Mitochondrial Function and its Impact in Metabolic Stress.". (2015): http://europepmc.org/abstract/med/25973983. 10.2174/0929867322666150514095910 Pantazi E; Folch-Puy E; Bejaoui M; Panisello A; Varela AT; Rolo AP; Palmeira CM; Roselló-Catafau J. "PPARa Agonist WY-14643 Induces SIRT1 Activity in Rat Fatty Liver Ischemia-Reperfusion Injury.". (2015): http://europepmc.org/abstract/med/26539534. 10.1155/2015/894679 Teodoro JS; Zouhar P; Flachs P; Bardova K; Janovska P; Gomes AP; Duarte FV; et al. "Enhancement of brown fat thermogenesis using chenodeoxycholic acid in mice.". (2014): http://europepmc.org/abstract/med/24310401. 10.1038/ijo.2013.230 Teodoro JS; Varela AT; Rolo AP; Palmeira CM. "High-fat and obesogenic diets: current and future strategies to fight obesity and diabetes.". (2014): http://europepmc.org/abstract/med/24842072. 10.1007/s12263-014-0406-6 Carmo MR; Menezes AP; Nunes AC; Pliássova A; Rolo AP; Palmeira CM; Cunha RA; Canas PM; Andrade GM. "The P2X7 receptor antagonist Brilliant Blue G attenuates contralateral rotations in a rat model of Parkinsonism through a combined control of synaptotoxicity, neurotoxicity and gliosis.". (2014): http://europepmc.org/abstract/med/24508709. 10.1016/j.neuropharm.2014.01.045 Duarte FV; Palmeira CM; Rolo AP. "The Role of microRNAs in Mitochondria: Small Players Acting Wide.". (2014): http://europepmc.org/abstract/med/25264560. 10.3390/genes5040865 Gomes AP; Price NL; Ling AJ; Moslehi JJ; Montgomery MK; Rajman L; White JP; et al. "Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.". (2013): http://europepmc.org/abstract/med/24360282. 10.1016/j.cell.2013.11.037 Duarte, F.V.; Gomes, A.P.; Teodoro, J.S.; Varela, A.T.; Moreno, A.J.M.; Rolo, A.P.; Palmeira, C.M.. "Dibenzofuran-induced mitochondrial dysfunction: Interaction with ANT carrier". Toxicology in Vitro 27 8 (2013): 2160-2168. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885795993&partnerID=MN8TOARS. 10.1016/j.tiv.2013.08.009 Rossato, L.G.; Costa, V.M.; Vilas-Boas, V.; De Lourdes Bastos, M.; Rolo, A.; Palmeira, C.; Remião, F.. "Therapeutic concentrations of mitoxantrone elicit energetic imbalance in H9c2 cells as an earlier event". Cardiovascular Toxicology 13 4 (2013): 413-425. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890559945&partnerID=MN8TOARS. 10.1007/s12012-013-9224-0 Teodoro, J.S.; Duarte, F.V.; Gomes, A.P.; Varela, A.T.; Peixoto, F.M.; Rolo, A.P.; Palmeira, C.M.. "Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: A possible role for SirT3 activation". Mitochondrion 13 6 (2013): 637-646. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884937949&partnerID=MN8TOARS. 10.1016/j.mito.2013.09.002 Teodoro, J.S.; Rolo, A.P.; Palmeira, C.M.. "The NAD ratio redox paradox: Why does too much reductive power cause oxidative stress?". Toxicology Mechanisms and Methods 23 5 (2013): 297-302. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878533789&partnerID=MN8TOARS. 10.3109/15376516.2012.759305 Teodoro, J.S.; Gomes, A.P.; Varela, A.T.; Duarte, F.V.; Rolo, A.P.; Palmeira, C.M.. "Uncovering the beginning of diabetes: The cellular redox status and oxidative stress as starting players in hyperglycemic damage". Molecular and Cellular Biochemistry 376 1-2 (2013): 103-110. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874278002&partnerID=MN8TOARS. 10.1007/s11010-012-1555-9 Hubbard, B.P.; Gomes, A.P.; Dai, H.; Li, J.; Case, A.W.; Considine, T.; Riera, T.V.; et al. "Evidence for a common mechanism of SIRT1 regulation by allosteric activators". Science 339 6124 (2013): 1216-1219. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874721105&partnerID=MN8TOARS. 10.1126/science.1231097 Gomes, A.P.; Duarte, F.V.; Nunes, P.; Hubbard, B.P.; Teodoro, J.S.; Varela, A.T.; Jones, J.G.; et al. "Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis". Biochimica et Biophysica Acta - Molecular Basis of Disease 1822 2 (2012): 185-195. http://www.scopus.com/inward/record.url?eid=2-s2.0-83255163155&partnerID=MN8TOARS. 10.1016/j.bbadis.2011.10.008 Rolo, A.P.; Teodoro, J.S.; Palmeira, C.M.. "Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis". Free Radical Biology and Medicine 52 1 (2012): 59-69. http://www.scopus.com/inward/record.url?eid=2-s2.0-84655169624&partnerID=MN8TOARS. 10.1016/j.freeradbiomed.2011.10.003 Palmeira, C.M.; Rolo, A.P.; Teodoro JS; Palmeira CM; Rolo AP; Teodoro, João Soeiro; Palmeira, Carlos Marques; Rolo, Anabela Pinto. "Mitochondrial membrane potential fluctuations associated with the metabolic states of mitochondria". Methods in Molecular Biology 810 (2012): 89-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-82355170970&partnerID=MN8TOARS. 10.1007/978-1-61779-382-0_6 Price, N.L.; Gomes, A.P.; Ling, A.J.Y.; Duarte, F.V.; Martin-Montalvo, A.; North, B.J.; Agarwal, B.; et al. "SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function". Cell Metabolism 15 5 (2012): 675-690. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860477354&partnerID=MN8TOARS. 10.1016/j.cmet.2012.04.003 Duarte, F.V.; Teodoro, J.S.; Rolo, A.P.; Palmeira, C.M.. "Exposure to dibenzofuran triggers autophagy in lung cells". Toxicology Letters 209 1 (2012): 35-42. http://www.scopus.com/inward/record.url?eid=2-s2.0-84155176935&partnerID=MN8TOARS. 10.1016/j.toxlet.2011.11.029 Teodoro, J.S.; Rolo, A.P.; Palmeira, C.M.. "Hepatic FXR: Key regulator of whole-body energy metabolism". Trends in Endocrinology and Metabolism 22 11 (2011): 458-466. http://www.scopus.com/inward/record.url?eid=2-s2.0-82455164172&partnerID=MN8TOARS. 10.1016/j.tem.2011.07.002 Varela, A.T.; Rolo, A.P.; Palmeira, C.M.. "Fatty liver and ischemia/reperfusion: Are there drugs able to mitigate injury?". Current Medicinal Chemistry 18 32 (2011): 4987-5002. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054860029&partnerID=MN8TOARS. 10.2174/092986711797535164 Nunes, P.M.; Jones, J.G.; Rolo, A.P.; Palmeira, C.M.M.; Carvalho, R.A.. "Ursodeoxycholic acid treatment of hepatic steatosis: A 13C NMR metabolic study". NMR in Biomedicine 24 9 (2011): 1145-1158. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054069550&partnerID=MN8TOARS. 10.1002/nbm.1672 Duarte, F.V.; Simões, A.M.; Teodoro, J.S.; Rolo, A.P.; Palmeira, C.M.. "Exposure to dibenzofuran affects lung mitochondrial function in vitro". Toxicology Mechanisms and Methods 21 8 (2011): 571-576. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053260979&partnerID=MN8TOARS. 10.3109/15376516.2011.576714 Rolo, A.P.; Gomes, A.P.; Palmeira, C.M.. "Regulation of mitochondrial biogenesis in metabolic syndrome". Current Drug Targets 12 6 (2011): 872-878. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955575803&partnerID=MN8TOARS. 10.2174/138945011795529056 Teodoro, J.S.; Simões, A.M.; Duarte, F.V.; Rolo, A.P.; Murdoch, R.C.; Hussain, S.M.; Palmeira, C.M.. "Assessment of the toxicity of silver nanoparticles in vitro: A mitochondrial perspective". Toxicology in Vitro 25 3 (2011): 664-670. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952039156&partnerID=MN8TOARS. 10.1016/j.tiv.2011.01.004 Varela, A.T.; Simões, A.M.; Teodoro, J.S.; Duarte, F.V.; Gomes, A.P.; Palmeira, C.M.; Rolo, A.P.. "Indirubin-3'-oxime prevents hepatic I/R damage by inhibiting GSK-3ß and mitochondrial permeability transition". Mitochondrion 10 5 (2010): 456-463. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955424602&partnerID=MN8TOARS. 10.1016/j.mito.2010.04.006 Simes, A.M.; Duarte, F.V.; Teodoro, J.S.; Rolo, A.P.; Palmeira, C.M.. "Exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin and tetraethyl lead affects lung mitochondria bioenergetics". Toxicology Mechanisms and Methods 20 1 (2010): 1-6. http://www.scopus.com/inward/record.url?eid=2-s2.0-77149123078&partnerID=MN8TOARS. 10.3109/15376510903527916 Rolo, A.P.; Teodoro, J.S.; Peralta, C.; Rosello-Catafau, J.; Palmeira, C.M.. "Prevention of I/R injury in fatty livers by ischemic preconditioning is associated with increased mitochondrial tolerance: The key role of ATPsynthase and mitochondrial permeability transition". Transplant International 22 11 (2009): 1081-1090. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349668693&partnerID=MN8TOARS. 10.1111/j.1432-2277.2009.00916.x Rolo, A.P.; Palmeira, C.M.; Cortopassi, G.A.. "Biosensor plates detect mitochondrial physiological regulators and mutations in vivo". Analytical Biochemistry 385 1 (2009): 176-178. http://www.scopus.com/inward/record.url?eid=2-s2.0-57749174647&partnerID=MN8TOARS. 10.1016/j.ab.2008.10.002 Varela, A.T.; Gomes, A.P.; Simões, A.M.; Teodoro, J.S.; Duarte, F.V.; Rolo, A.P.; Palmeira, C.M.. "Indirubin-3'-oxime impairs mitochondrial oxidative phosphorylation and prevents mitochondrial permeability transition induction". Toxicology and Applied Pharmacology 233 2 (2008): 179-185. http://www.scopus.com/inward/record.url?eid=2-s2.0-56049123388&partnerID=MN8TOARS. 10.1016/j.taap.2008.08.005 Teodoro, J.S.; Rolo, A.P.; Duarte, F.V.; Simões, A.M.; Palmeira, C.M.. "Differential alterations in mitochondrial function induced by a choline-deficient diet: Understanding fatty liver disease progression". Mitochondrion 8 5-6 (2008): 367-376. http://www.scopus.com/inward/record.url?eid=2-s2.0-54949089576&partnerID=MN8TOARS. 10.1016/j.mito.2008.07.008 Palmeira, C.M.; Rolo, A.P.; Berthiaume, J.; Bjork, J.A.; Wallace, K.B.. "Hyperglycemia decreases mitochondrial function: The regulatory role of mitochondrial biogenesis". Toxicology and Applied Pharmacology 225 2 (2007): 214-220. http://www.scopus.com/inward/record.url?eid=2-s2.0-36048941086&partnerID=MN8TOARS. 10.1016/j.taap.2007.07.015 Moreira, P.I.; Rolo, A.P.; Sena, C.; Seiça, R.; Oliveira, C.R.; Santos, M.S.. "Insulin attenuates diabetes-related mitochondrial alterations: A comparative study". Medicinal Chemistry 2 3 (2006): 299-308. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746153746&partnerID=MN8TOARS. 10.2174/157340606776930754 Rolo, A.P.; Palmeira, C.M.. "Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress". Toxicology and Applied Pharmacology 212 2 (2006): 167-178. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645765312&partnerID=MN8TOARS. 10.1016/j.taap.2006.01.003 Teodoro, J.; Rolo, A.P.; Oliveira, P.J.; Palmeira, C.M.. "Decreased ANT content in Zucker fatty rats: Relevance for altered hepatic mitochondrial bioenergetics in steatosis". FEBS Letters 580 8 (2006): 2153-2157. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645241135&partnerID=MN8TOARS. 10.1016/j.febslet.2006.02.078 Palmeira, C.M.; Rolo, A.P.. "Mitochondrially-mediated toxicity of bile acids". Toxicology 203 1-3 (2004): 1-15. http://www.scopus.com/inward/record.url?eid=2-s2.0-4444311570&partnerID=MN8TOARS. 10.1016/j.tox.2004.06.001 Oliveira, P.J.; Rolo, A.P.; Sardão, V.A.; Monteiro, P.; Gonçalves, L.; Providência, L.A.; Palmeira, C.M.; Moreno, A.J.M.. "Advantages in the use of carvedilol versus propranolol for the protection of cardiac mitochondrial function". Revista Portuguesa de Cardiologia 23 10 (2004): 1291-1298. http://www.scopus.com/inward/record.url?eid=2-s2.0-10644236410&partnerID=MN8TOARS. Rolo, A.P.; Palmeira, C.M.; Holy, J.M.; Wallace, K.B.. "Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: The switch between apoptosis and necrosis". Toxicological Sciences 79 1 (2004): 196-204. http://www.scopus.com/inward/record.url?eid=2-s2.0-2442644019&partnerID=MN8TOARS. 10.1093/toxsci/kfh078 Oliveira, P.J.; Seica, R.; Santos, D.L.; Rolo, A.P.; Sardao, V.A.; Ferreira, F.M.L.; Palmeira, C.M.; Santos, M.S.; Moreno, A.J.M.. "Vitamin E or coenzyme Q10 administration is not fully advantageous for heart mitochondrial function in diabetic goto kakizaki rats". Mitochondrion 3 6 (2004): 337-345. http://www.scopus.com/inward/record.url?eid=2-s2.0-1942484378&partnerID=MN8TOARS. 10.1016/j.mito.2004.02.005 Oliveira, P.J.; Esteves, T.; Rolo, A.P.; Palmeira, C.M.; Moreno, A.J.M.. "Carvedilol Inhibits the Mitochondrial Permeability Transition by an Antioxidant Mechanism". Cardiovascular Toxicology 4 1 (2004): 11-20. http://www.scopus.com/inward/record.url?eid=2-s2.0-1942486470&partnerID=MN8TOARS. 10.1385/CT:4:1:11 Rolo, Anabela P.; Oliveira, Paulo J.; Moreno, Antonio J.; Palmeira, Carlos M.; Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.; Palmeira, C.M.. "Chenodeoxycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: protective role of carvedilol". Mitochondrion 2 4 (2003): 305-311. http://dx.doi.org/10.1016/s1567-7249(03)00007-2. 10.1016/s1567-7249(03)00007-2 Ferreira, F. M.; Oliveira, P. J.; Rolo, A. P.; Santos, M. S.; Moreno, A. J.; da Cunha, M. F.; Seiça, R.; Palmeira, C. M.. "Cholestasis induced by chronic treatment with a-naphthyl-isothiocyanate (ANIT) affects rat renal mitochondrial bioenergetics". Archives of Toxicology 77 4 (2003): 194-200. http://dx.doi.org/10.1007/s00204-003-0441-3. 10.1007/s00204-003-0441-3 Rolo, A.P.; Palmeira, C.M.; Wallace, K.B.. "Mitochondrially mediated synergistic cell killing by bile acids". Biochimica et Biophysica Acta - Molecular Basis of Disease 1637 1 (2003): 127-132. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037454711&partnerID=MN8TOARS. 10.1016/S0925-4439(02)00224-7 Oliveira, P.J.; Rolo, A.P.; Seiça, R.; Santos, M.S.; Palmeira, C.M.; Moreno, A.J.. "Reduction in cardiac mitochondrial calcium loading capacity is observable during a-naphthylisothiocyanate-induced acute cholestasis: A clue for hepatic-derived cardiomyopathies?". Biochimica et Biophysica Acta - Molecular Basis of Disease 1637 1 (2003): 39-45. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037454702&partnerID=MN8TOARS. 10.1016/S0925-4439(02)00212-0 Oliveira, P.J.; Seiça, R.; Coxito, P.M.; Rolo, A.P.; Palmeira, C.M.; Santos, M.S.; Moreno, A.J.M.. "Enhanced permeability transition explains the reduced calcium uptake in cardiac mitochondria from streptozotocin-induced diabetic rats". FEBS Letters 554 3 (2003): 511-514. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242541631&partnerID=MN8TOARS. 10.1016/S0014-5793(03)01233-X Palmeira, C.M.; Ferreira, F.M.; Rolo, A.P.; Oliveira, P.J.; Santos, M.S.; Moreno, A.J.; Cipriano, M.A.; Martins, M.I.; Seiça, R.. "Histological changes and impairment of liver mitochondrial bioenergetics after long-term treatment with a-naphthyl-isothiocyanate (ANIT)". Toxicology 190 3 (2003): 185-196. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042133192&partnerID=MN8TOARS. 10.1016/S0300-483X(03)00163-X Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Pameira, C.M.. "Protection against post-ischemic mitochondrial injury in rat liver by silymarin or TUDC". Hepatology Research 26 3 (2003): 217-224. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042167601&partnerID=MN8TOARS. 10.1016/S1386-6346(03)00108-6 Destainville, A.; Rolo, A.; Champion, E.; Bernache-Assollant, D.. "Synthesis and characterization of beta tricalcium phosphate". Key Engineering Materials 240-242 (2003): 489-492. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037247010&partnerID=MN8TOARS. Oliveira, P.J.; Esteves, T.; Rolo, A.P.; Monteiro, P.; Gonçalves, L.; Palmeira, C.M.; Moreno, A.J.. "Carvedilol: Relation between antioxidant activity and inhibition of the mitochondrial permeability transition". Revista Portuguesa de Cardiologia 22 1 (2003): 55-62. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346034614&partnerID=MN8TOARS. Oliveira, P.J.; Rolo, A.P.; Seiça, R.; Santos, M.S.; Palmeira, C.M.; Moreno, A.J.. "Chronic cholestasis and cardiac mitochondrial function in wistar rats: A model for cardiovascular alterations in chronic liver disease?". Revista Portuguesa de Cardiologia 22 1 (2003): 67-75. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344951202&partnerID=MN8TOARS. Oliveira, P.J.; Rolo, A.P.; Seiça, R.; Santos, M.S.; Palmeira, C.M.; Moreno, A.J.M.. "Cardiac mitochondrial calcium loading capacity is severely affected after chronic cholestasis in Wistar rats". Journal of Investigative Medicine 51 2 (2003): 86-94. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037338705&partnerID=MN8TOARS. Rolo, A.P.; Oliveira, P.J.; Seiça, R.; Santos, M.S.; Moreno, A.J.; Palmeira, C.M.. "Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of a-naphthylisothiocyanate". Toxicology and Applied Pharmacology 182 1 (2002): 20-26. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036070550&partnerID=MN8TOARS. 10.1006/taap.2002.9434 Rolo, A.P.; Palmeira, C.M.; Wallace, K.B.. "Interactions of combined bile acids on hepatocyte viability: Cytoprotection or synergism". Toxicology Letters 126 3 (2002): 197-203. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037033967&partnerID=MN8TOARS. 10.1016/S0378-4274(01)00464-7 Oliveira, P.J.; Rolo, A.P.; Seiça, R.; Sardão, V.; Monteiro, P.; Gonçalves, L.; Providência, L.; et al. "Impact of diabetes on induction of the mitochondrial permeability transition.". Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 21 6 (2002): 759-766. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036616238&partnerID=MN8TOARS. Oliveira, P.J.; Rolo, A.P.; Monteiro, P.; Conçalves, L.; Palmeira, C.M.; Moreno, A.J.. "Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase - What role in myocardial ischemia and reperfusion?". Revista Portuguesa de Cardiologia 21 12 (2002): 1447-1455. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036998602&partnerID=MN8TOARS. Rolo, A.P.; Oliveira, P.J.; Seiça, R.; Santos, M.S.; Moreno, A.J.; Palmeira, C.M.. "Disruption of mitochondrial calcium homeostasis after chronic a-naphthylisothiocyanate administration: Relevance for cholestasis". Journal of Investigative Medicine 50 3 (2002): 193-200. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036092085&partnerID=MN8TOARS. Oliveira, P.J.; Rolo, A.P.; Palmeira, C.M.; Moreno, A.J.M.. "Carvedilol reduces mitochondrial damage induced by hypoxanthine/xanthine oxidase: Relevance to hypoxia/reoxygenation injury". Cardiovascular Toxicology 1 3 (2001): 205-213. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035750084&partnerID=MN8TOARS. 10.1385/CT:1:3:205 Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Palmeira, C.M.. "Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria". Bioscience Reports 21 1 (2001): 73-80. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034899577&partnerID=MN8TOARS. 10.1023/A:1010438202519 Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Palmeira, C.M.. "Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore". Biochemical Pharmacology 61 11 (2001): 1449-1454. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035370544&partnerID=MN8TOARS. 10.1016/S0006-2952(01)00620-7 Oliveira, P.J.; Rolo, A.P.; Sardão, V.A.; Coxito, P.M.; Palmeira, C.M.; Moreno, A.J.M.. "Carvedilol in heart mitochondria - Protonophore or opener of the mitochondrial KATP channels?". Life Sciences 69 2 (2001): 123-132. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035371154&partnerID=MN8TOARS. 10.1016/S0024-3205(01)01109-2 Oliveira, P.J.; Coxito, P.M.; Rolo, A.P.; Santos, D.L.; Palmeira, C.M.; Moreno, A.J.M.. "Inhibitory effect of carvedilol in the high-conductance state of the mitochondrial permeability transition pore". European Journal of Pharmacology 412 3 (2001): 231-237. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035793307&partnerID=MN8TOARS. 10.1016/S0014-2999(01)00745-2 Oliveira, P.J.; Rolo, A.P.; Seiãça, R.; Palmeira, C.M.; Santos, M.S.; Moreno, A.J.M.. "Decreased susceptibility of heart mitochondria from diabetic GK rats to mitochondrial permeability transition induced by calcium phosphate". Bioscience Reports 21 1 (2001): 45-53. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034905572&partnerID=MN8TOARS. Rolo, A.P.; Palmeira, C.M.. "Cholestasis and mitochondrial dysfunction: A review". Toxic Substance Mechanisms 19 2 (2000): 83-98. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034458883&partnerID=MN8TOARS. 10.1080/10769180052008878 Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Palmeira, C.M.. "Bile acids affect liver mitochondrial bioenergetics: Possible relevance for cholestasis therapy". Toxicological Sciences 57 1 (2000): 177-185. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033852206&partnerID=MN8TOARS.
Capítulo de livro	Teodoro, João Soeiro; Rolo, Anabela Pinto; Palmeira, Carlos Manuel Marques. "Mitochondrial Bioenergetic Assays as a Standard Protocol for Toxicological and Metabolic Assessment". In Methods in Molecular Biology, 231-241. Springer US, 2021. 10.1007/978-1-0716-1091-6_16 Teodoro, João S.; Machado, Ivo F.; Palmeira, Carlos M.; Rolo, Anabela P.. "Determination of Oxidative Phosphorylation Complexes Activities". In Methods in Molecular Biology, 17-31. Springer US, 2021. 10.1007/978-1-0716-1433-4_2 Rolo AP. "Evaluation of mitochondrial membrane potential using fluorescent dyes or a membrane-permeable cation (TPP+) electrode in isolated mitochondria and intact cells". In Immunometabolism: Methods and Protocols. Springer, 2020. No prelo Amorim, Joao Alves; Teodoro, Joao Soeiro; Palmeira, Carlos Marques; Rolo, Anabela Pinto. "Sirtuins and Bile Acids: Potential Anti-obesity Strategies Targeting Mitochondria". In Anti-Obesity Drug Discovery and Development: Volume 4, 57-97. BENTHAM SCIENCE PUBLISHERS, 2018. 10.2174/9781681085586118040005 Alexandrino, Henrique; Rolo, Anabela; Tralhão, José Guilherme; Castro e Sousa, Francisco; Palmeira, Carlos. "Mitochondria in Liver Regeneration: Energy Metabolism and Posthepatectomy Liver Dysfunction". In Mitochondrial Biology and Experimental Therapeutics, 127-152. Springer International Publishing, 2018. Publicado • 10.1007/978-3-319-73344-9_8 Teodoro, João S.; Duarte, Filipe V.; Rolo, Anabela P.; Palmeira, Carlos M.. "Mitochondria as a Target for Safety and Toxicity Evaluation of Nutraceuticals". In Nutraceuticals, 387-400. Elsevier, 2016. 10.1016/b978-0-12-802147-7.00028-0 Duarte, Filipe V.; Palmeira, Carlos M.; Rolo, Anabela P.. "The Emerging Role of MitomiRs in the Pathophysiology of Human Disease". In Advances in Experimental Medicine and Biology, 123-154. Springer International Publishing, 2015. 10.1007/978-3-319-22671-2_8 Teodoro, João S.; Palmeira, Carlos M.; Rolo, Anabela P.. "Determination of Oxidative Phosphorylation Complexes Activities". In Methods in Molecular Biology, 71-84. Springer New York, 2015. 10.1007/978-1-4939-1875-1_7 Palmeira, Carlos M.; Duarte, Filipe V.; Teodoro, João S.; Varela, Ana T.; Rolo, Anabela P.. "Biomarkers of mitochondrial dysfunction and toxicity". In Biomarkers in Toxicology, 847-861. Elsevier, 2014. 10.1016/b978-0-12-404630-6.00051-8
Edição de número de revista	Rolo AP. "Metabolic Diseases: Drugs and Mitochondrial Targets". Current Medicinal Chemistry (2015): Publicado • 10.2174/092986732220150722123617
Livro	Palmeira, C.M.; Rolo, A.P.. Mitochondrial Regulation: Methods and Protocols. Springer. 2015. Publicado • 10.1007/978-1-4939-1875-1 • Editor

Atividades

Orientação

	Título / Tema Papel desempenhado	Curso (Tipo) Instituição / Organização
2021 - Atual	Role of epigenetic remodelling in liver regeneration Orientador	Biociências (Doutoramento)
2020/09 - 2021/11	The role of Sestrin-2 in cellular adaptation to hypoxic stress Orientador	Cellular and Molecular Biology (Mestrado) Universidade de Coimbra, Portugal
2020 - 2021	The potential role of sestrin 2 in liver regeneration Orientador	Universidade de Coimbra, Portugal
2020 - 2020	Programa Estágios de Verão - Gabinete de Saídas Profissionais da Universidade de Coimbra Orientador
2020 - 2020	Programa Estágios de Verão - Gabinete de Saídas Profissionais da Universidade de Coimbra Orientador
2020 - 2020	Sestrin2 and mitochondrial quality control: potential impact in myogenic differentiation Orientador	Universidade de Coimbra, Portugal
2019 - 2019	Sestrina 2 e modulação da função mitocondrial Orientador
2018 - 2019	Modulation of complex I and oxidative capacity in cells under metabolic stress: the crosstalk between miR-378 and metformin Orientador	Biologia Celular e Molecular (Mestrado) Universidade de Coimbra, Portugal
2015 - 2019	Understanding the underlying mechanisms regulating aging and longevity Coorientador	Biociências (Doutoramento) Universidade de Coimbra, Portugal
2014 - 2019	Detoxification of fuel oversupply in WAT through metabolic futile cycling induced by bile acids Coorientador	Universidade de Coimbra, Portugal
2018 - 2018	Programa Estágios de Verão - Gabinete de Saídas Profissionais da Universidade de Coimbra Orientador	Universidade de Coimbra, Portugal
2018 - 2018	Efeitos da metformina na mitofagia, função mitocondrial e metabolismo dos mioblastos C2C12 Orientador
2017 - 2018	Effects of blueberry juice on the evolution of hepatic dysfunction in an animal model of prediabetes Coorientador	Bioquímica Universidade de Coimbra, Portugal
2017 - 2017	Mitohormesis como estratégia terapêutica – expressão de mitoDsRed em células C2C12 para otimização do modelo experimental Orientador
2016 - 2017	The role of dynamins and dynamin-related protein 1 (Drp 1) in the regulation of mitochondrial and peroxisomal fission Coorientador	Biologia Celular e Molecular (Mestrado) Universidade de Coimbra, Portugal
2016 - 2017	Sestrin 2-mediated mitophagy: potential regulation of mitohormesis and promotion of metabolic health Orientador	Biologia Celular e Molecular (Mestrado) Universidade de Coimbra, Portugal
2016 - 2017	Effects of bariatric surgery on glycation and vascular remodeling in an obese diabetic animal model Coorientador	Bioquímica (Mestrado) Universidade de Coimbra, Portugal
2016 - 2017	Alteration of dopaminergic signaling after carotid body denervation in the modulation of adipose tissue function in the metabolic syndrome Coorientador
2016 - 2016	Programa Estágios de Verão - Gabinete de Saídas Profissionais da Universidade de Coimbra Orientador	Universidade de Coimbra, Portugal
2014 - 2015	Remodeling of white adipose tissue and metabolic disease Orientador	Bioquímica (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014 - 2015	Dissecting signaling pathways that control glia migration in the developing Drosophila retina Coorientador	Biologia Molecular e Celular (Mestrado) Universidade de Aveiro Departamento de Biologia, Portugal
2014 - 2015	Role of the sphingomyelinase Isc1p in the regulation of iron homeostasis in Saccharomyces cerevisiae Coorientador	Biologia Molecular e Celular (Mestrado) Universidade de Aveiro Departamento de Biologia, Portugal
2014 - 2015	O efeito pro´-carcinoge´nico do 17ß-estradiol na captac¸a~o de nutrientes essenciais para as ce´lulas MCF-7 Coorientador	Biologia Molecular e Celular (Mestrado) Universidade de Aveiro Departamento de Biologia, Portugal
2014 - 2015	Characterization of the glial scar tissue in a murine model of spinal cord compression, with focus on hyaluronan Coorientador	Biologia Molecular e Celular (Mestrado) Universidade de Aveiro Departamento de Biologia, Portugal
2014 - 2015	Dissecting the role of Profilin-1 in microglial cell function: the impacto n reactive oxygen species production Coorientador	Biologia Molecular e Celular (Mestrado) Universidade de Aveiro Departamento de Biologia, Portugal
2014 - 2015	Modulation of mitochondrial stress response by Sestrin 2 Orientador	Biologia Molecular e Celular (Mestrado) Universidade de Aveiro Departamento de Biologia, Portugal
2014 - 2014	Modulação do ciclo TG/ (GL+ FFA) como alvo terapêutico na obesidade Orientador	Biologia Molecular e Celular (Mestrado) Universidade de Aveiro, Portugal
2012 - 2012	Efeito do 3-bromopiruvato na pluripotência de células estaminais embrionárias Coorientador	Biologia Molecular e Celular (Mestrado) Universidade de Aveiro, Portugal
2008 - 2012	Regulation of mitochondrial function in ischemia/reperfusion: looking for therapeutic strategies in fatty livers Coorientador	Biologia (Doutoramento) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 - 2012	Unravelling new roles for SIRT1 in mitochondrial biology Coorientador	Biologia (Doutoramento) Universidade de Coimbra, Portugal
2007 - 2012	Physiologic pathways and molecular mechanisms regulating energy homeostasis in diabetes Coorientador	Biociências (Doutoramento) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2012	Dibenzofuran exposure: cellular and mitochondrial damage Coorientador	Biociências (Doutoramento) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2010	Efeitos do tratamento com berberina na sinalização por AMPK e estimulação da função mitocondrial num modelo de obesidade induzida por dieta Coorientador	Biologia Celular e Molecular (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2009	Efeito da metformina na função mitocondrial diabética Coorientador	Biologia Animal (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2009	O efeito do UDCA na terapia anti-colestática: relevância para a função mitocondrial Coorientador	Biologia Animal (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2008	Efeitos do Chitosan na função mitocondrial hepática de ratos Goto-Kakizaki Coorientador	Biologia (Licenciatura/Bacharelato) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2008	Indirubina altera a fosforilação oxidativa mitocondrial e previne a indução de permeabilidade transitória Coorientador	Biologia (Licenciatura/Bacharelato) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006 - 2007	Alteração da função mitocondrial como consequência da exposição a dioxinas e outros poluentes ambientais Coorientador	Biologia (Licenciatura/Bacharelato) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006 - 2007	Tolerância mitocondrial e pré-condicionamento isquémico: importância na prevenção da lesão hepática induzida por isquémia-reperfusão Coorientador	Biologia (Licenciatura/Bacharelato) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006 - 2007	Alteração da função mitocondrial em patologias pulmonares: consequências da exposição a dioxinas e outros poluentes ambientais Coorientador	Bioquímica (Licenciatura/Bacharelato) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006 - 2007	Esteatose hepática: mecanismos celulares com relevância na função mitocondrial Coorientador	Biologia Celular (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2005 - 2006	Toxicidade renal de ácidos biliares ao nível do metabolismo mitocondrial Coorientador	Biologia (Licenciatura/Bacharelato) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2004 - 2005	Disfunção mitocondrial na esteatose hepática Coorientador	Biologia (Licenciatura/Bacharelato) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Participação em evento

	Descrição da atividade Tipo de evento	Nome do evento Instituição / Organização
2020/01/21 - 2020/01/21	Oficina BCM nas escolas – Gabinete de Apoio à Divulgação da Universidade de Coimbra. Atividades teórico-práticas no âmbito da Biologia Celular e Molecular para alunos do 11o ano na Escola Secundária Lima de Faria – Cantanhede. Oficina (workshop)	Universidade de Coimbra, Portugal
2019/05/22 - 2019/05/24	Machado I, Palmeira CM, Rolo AP. Modulation of complex I and oxidative capacity in cells under metabolic stress Congresso	53rd Annual Meeting of the European Society for Clinical Investigation
2019/05/22 - 2019/05/24	Teodoro J, Rolo A, Silva R, Machado I, Rosello-Catafau J, Steegborn C, Palmeira C. Novel avenues of ischemia/reperfusion injury pervention: lessons from a soluble adenylyl cyclase inhibitor and a SirT3 activator.	MitoPorto 2019 - International Symposium of the Consortium for Mitochondrial Research
2019/01/18 - 2019/01/18	Oficina BCM nas escolas – Gabinete de Apoio à Divulgação da Universidade de Coimbra. Atividades teórico-práticas no âmbito da Biologia Celular e Molecular para alunos do 11o ano na Escola Básica e Secundária Dr. Pascoal José de Melo – Ansião. Oficina (workshop)	Universidade de Coimbra, Portugal
2019/01/14 - 2019/01/14	Oficina BCM nas escolas – Gabinete de Apoio à Divulgação da Universidade de Coimbra. Atividades teórico-práticas no âmbito da Biologia Celular e Molecular para alunos do 11o ano na Escola Secundária Lima de Faria – Cantanhede. Oficina (workshop)	Universidade de Coimbra, Portugal
2019 - 2019	Atividades na área do saber – Universidade de Verão 2019 (atividades na área da Biologia Celular e Molecular, dirigidas a alunos do ensino secundário) Outro	Universidade de Coimbra, Portugal
2018/11/14 - 2018/11/18	Amorim J, Tackur S, Bonkowski MS, Rolo AP, Palmeira CM, Sinclair DA. A new mouse model to unravel the mechanism of SIRT1 activation. Congresso	Gerontological Society of America Annual Meeting
2018/11/07 - 2018/11/07	Amorim J, Tackur S, Bonkowski MS, Rolo AP, Palmeira CM, Sinclair DA. An activation-defective mouse mutant as a model to unravel the mechanisms of SIRT1 activators	Fourth Annual Northeast Glenn Foundation Symposium on the Biology of Aging (New Haven, EUA, 7 de novembro de 2018)
2018/10/01 - 2018/10/05	Amorim J, Tackur S, Bonkowski MS, Rolo AP, Palmeira CM, Sinclair DA. An activation-defective mouse mutant as a model to unravel the mechanisms of SIRT1 activators.	Cold Spring Harbor Laboratory: Mechanisms of Aging (Cold Spring Harbor, EUA, 1- 5 de outubro de 2018)
2018/06/19 - 2018/06/20	Nunes S, Castela A, Rolo AP, Palmeira CM, Andre´ MA, Cavadas C, Pintado MM, Reis F. Blueberry juice attenuates liver injury progression in a rat model of diet-induced prediabetes.	1st Meeting in Translational Pharmacology, 38th SEF national meeting/9th SEFF meeting (Santiago de Compostela, Espanha, 19-20 de junho de 2018)
2018/06/04 - 2018/06/07	Teodoro JS, Amorim JA, Silva R, Rolo AP, Steegborn C, Sinclair DA, Palmeira CM. Sirtuin-cAMP crosstalk in metabolic diseases: nucleus versus mitochondria.	19th Biennial Meeting of the Society for Free Radical Research International (Lisboa, 4-7 de junho de 2018)
2018/05/30 - 2018/06/01	Teodoro JS, Rolo AP, Carvalho RA, Palmeira CM. Exploring the role of the bile acid receptor TGR5 in bile acid mediated obesity control: Novel insights from a CRISPR/Cas9 adipocyte model.	52nd Annual Meeting of the European Society for Clinical Investigation (Barcelona, Espanha, 30 de maio - 1 de junho de 2018)
2018/03/08 - 2018/03/10	Martins R, Teodoro J, Rolo A, Furtado E, Palmeira C, Tralha~o JG. Novos fatores de progno´stico precoces na transplantac¸a~o hepa´tica: avaliac¸a~o bioenerge´tica e da func¸a~o mitocondrial.	XXXVIII Congresso Nacional de Cirurgia (Lisboa, 8-10 de marc¸o de 2018)
2018 - 2018	Dia de Investigação do DCV 2018 Outro	Universidade de Coimbra, Portugal
2018 - 2018	Atividades na área do saber – Universidade de Verão 2018 (atividades na área da Biologia Celular e Molecular, dirigidas a alunos do ensino secundário) Outro
2017/05/17 - 2017/05/20	Alexandrino A, Teodoro JS, Donato H, Martins R, Sero^dio M, Martins M, Rolo A, Tralha~o JG, Palmeira C, Castro e Sousa F. Mitochondrial bioenergetics and biogenesis are involved in the regenerative response of the human liver in two-stage hepatectomies.	51st Annual Meeting of the European Society for Clinical Investigation (Ge´nova, Ita´lia, 17-20 de maio de 2017)
2017/03/30 - 2017/04/01	Alexandrino A, Teodoro JS, Donato H, Martins R, Sero^dio M, Martins M, Rolo A, Tralha~o JG, Palmeira C, Castro e Sousa F. Metabolismo Energe´tico nas Hepatectomia a Dois Tempos: Adaptac¸a~o da Func¸a~o Mitocondrial como Feno´meno Central na Regenerac¸a~o Hepa´tica.	Congresso Portugue^s de Hepatologia (Porto, 30-1 de Abril de 2017)
2017/03/16 - 2017/03/18	Martins R, Teodoro J, Rolo A, Furtado E, Palmeira C, Tralha~o JG. Avaliac¸a~o da efica´cia do R5 na preservac¸a~o da atividade mitocondrial na transplantac¸a~o hepa´tica.	XXXVII Congresso Nacional de Cirurgia (Figueira da Foz, 16-18 de marc¸o de 2017)
2017 - 2017	Dia de Investigação do DCV 2017 Outro	Universidade de Coimbra, Portugal
2016/10/24 - 2016/10/26	Alexandrino A, Teodoro JS, Donato H, Martins R, Sero^dio M, Martins M, Rolo A, Tralha~o JG, Palmeira C, Castro e Sousa F. Bioenergetic adaptations of the human liver in two-stage hepatectomy with portal vein ligation – how liver regeneration correlates with mitochondrial energy status.	7th World Congress on Targeting Mitochondria (Berlim, Alemanha, 24-26 de outubro de 2016)
2016/10/13 - 2016/10/15	Martins R, Teodoro J, Rolo A, Furtado E, Palmeira C, Tralha~o JG. Avaliac¸a~o da efica´cia do RM3365 na preservac¸a~o da atividade mitocondrial na transplantac¸a~o hepa´tica.	XIII Congresso Portugue^s de Transplantac¸a~o/ XV Congresso Luso Brasileiro de Transplantac¸a~o/ II Encontro Ibe´rico de Transplantac¸a~o (Porto, 13-15 de outubro, 2016)
2016/10/02 - 2016/10/09	Pereira LC, Duarte FV, Varela AT, Rolo AP, Palmeira CMM, Dorta DJ. Autophagic process is activated in BDE-153-induced toxicity.	14th International Congress of Toxicology (Merida, Me´xico, 2-9 de outubro de 2016)
2016/04/27 - 2016/04/29	Teodoro JS, Varela AT, Duarte FV, Rolo AP, Palmeira CM. Prevention of hepatic ischemia/reperfusion damage in a surgical context: The key role of preservation of mitochondrial function.	50th Annual Scientific Meeting of the European Society for Clinical Investigation (Paris, Franc¸a, 27-29 de abril de 2016)
2016/03/03 - 2016/03/05	Martins R, Teodoro J, Rolo A, Furtado E, Palmeira C, Tralhãoo JG. Liver transplantation: evaluation of mitochondrial activity in animal model.	XXXVI Congresso Nacional de Cirurgia (Lisboa, 3-5 de marc¸o de 2016)
2016 - 2016	Ciência Viva no Laboratório Oficina (workshop)	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2015/09/13 - 2015/09/16	Silva MP, Pereira, LC, Duarte FV, Rolo AP, Palmeira CMM, Dorta DJ. Brominated flame retardant (BDE-47) induces autophagic processes in HepG2 cells.	51st Congress of the European Societies of Toxicology (Porto, 13-16 de setembro de 2015)
2015/09/13 - 2015/09/16	Panzani E, Bejaoui M, Folch-Puy E, Rolo AP, Palmeira CM, Gerousi M, Rosello-Catafau J. Angiotensin II type 1 receptor inhibition and SIRT1 activation in rat reduced- size orthotopic liver transplantation.	17th Congress of the European Society for Organ Transplantation (Bruxelas, Be´lgica, 13-16 de setembro de 2015)
2015/05/27 - 2015/05/30	Varela AT, Duarte FV, Teodoro JS, Gomes AP, Palmeira CM, Rolo AP. Novel strategies to prevent ischemia/reperfusion damage in fatty liver surgery: The effects of NAD(+) and indirubin on mitochondrial function.	49th Annual Scientific Meeting of the European Society for Clinical Investigation (Cluj-Napoca, Rome´nia, 27-30 de maio de 2015)
2015/03/05 - 2015/03/07	Alexandrino H, Varela AT, Oliveira RC, Cardoso J, Duarte FV, Teodoro JS, Rolo A, Cipriano MA, Tralha~o JG, Prado e Castro L, Palmeira C, Castro e Sousa F. Hepatotoxicidade da Quimioterapia: Validac¸a~o de um Modelo Animal.	XXXV Congresso Nacional de Cirurgia (Figueira da Foz, 5-7 de marc¸o de 2015)
2015/02/13 - 2015/02/14	Alexandrino A, Varela AT, Ferreira L, Martins R, Duarte FV, Teodoro JS, Serôdio M, Martins M, Rolo A, Tralhão JG, Palmeira C, Castro e Sousa F. Função Mitocondrial: Factor Relevante na Disfunção Hepatocelular pós-Hepatectomia?	Congresso Português de Hepatologia (Lisboa, 13-14 de fevereiro de 2015)
2015 - 2015	Ciência Viva no Laboratório Oficina (workshop)	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014 - 2014	The effects of Berberine on high fat-fed hepatic rat mitochondrial function: a possible role for Sirt3 Encontro	48th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI) European Society for Clinical Investigation, Países Baixos
2014 - 2014	The Mitochondrial Effects of a Chronic Exposure to a Low-Dose of Silver Nanoparticles Are Rescued by an Antioxidant Encontro	53rd Meeting of the Society of Toxicology Society of Toxicology, Estados Unidos
2014 - 2014	Mitochondria in glutamatergic nerve terminals are selectively affected by exposure to Aß1-42 modeling early Alzheimer's disease Conferência	International Bordeaux Neurocampus / Brain Conference Fédération Bordeaux Neurocampus, França
2014 - 2014	Exposure to silver nanoparticles: can the mitochondrial damage be rescued by an antioxidant? Congresso	XVIII Congress of the Portuguese Biochemical Society Sociedade Portuguesa de Bioquímica, Portugal
2014 - 2014	"Pergunta-me Ciência" Oficina (workshop)	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014 - 2014	"Pergunta-me Ciência" Oficina (workshop)	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2012 - 2012	SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function Simpósio	Keystone Symposia on Molecular and Cellular Biology: Sirtuins in Metabolism, Aging and Disease Keystone Symposia, Estados Unidos
2012 - 2012	Potential Role of SIRT1 preventing mitochondrial dysfunction by maintaining the balance between nuclear and mitochondrial ETC components Simpósio	Keystone Symposia on Molecular and Cellular Biology: Sirtuins in Metabolism, Aging and Disease Keystone Symposia, Estados Unidos
2012 - 2012	New insights into the role of sirtuins in aging and age-related diseases Simpósio	Keystone Symposia on Molecular and Cellular Biology: Sirtuins in Metabolism, Aging and Disease Keystone Symposia, Estados Unidos
2011 - 2011	Generation of an inducible wholebody SIRT1 knockout mouse to probe the mechanisms by which SIRT1 and Resveratrol improve metabolic function Conferência	Cell Symposia: Metabolism & Aging Conference
2011 - 2011	Modulation of adenosine receptors as regulatory elements in preconditioning Congresso	2nd World Congress on Targeting Mitochondria
2011 - 2011	Dibenzofuran-Induced Mitochondrial Dysfunction: Effects of ANT Interaction Congresso	2nd World Congress on Targeting Mitochondria
2011 - 2011	“Hyperglycemic Memory”: Permanent Cellular Damage in a Transient Insult - A Mitochondrial Perspective Congresso	2nd World Congress on Targeting Mitochondria
2010 - 2010	Generation of inducible whole body SIRT1 knockout mice to avoid developmental defects and test the effects of pharmacological SIRT1 activation Conferência	Molecular genetics of Aging, Cold Spring Harbour Laboratories Cold Spring Harbor Laboratory, Estados Unidos
2010 - 2010	Berberine administration stimulates mitochondrial function in a model of diet-induced obesity Conferência	Targeting Mitochondria
2010 - 2010	Mitochondrial-mediated Dibenzofuran toxicity Congresso	XVII National Congress of Biochemistry Sociedade Portuguesa de Bioquímica, Portugal
2010 - 2010	AMPK signaling regulated by Berberine and stimulation of mitochondria function in a model of diet-induced obesity Congresso	XVII National Congress of Biochemistry Sociedade Portuguesa de Bioquímica, Portugal
2010 - 2010	Decreased ANTCypD interaction is associated with the protective effect of indirubin in hepatic preconditioning Congresso	XVII National Congress of Biochemistry Sociedade Portuguesa de Bioquímica, Portugal
2009/04/01 - 2009/04/04	Rosiglitazone/Metformin increases mitochondrial biogenesis in Goto-Kakizaki rats: Bioenergetic consequences for diabetes Congresso	3rd International Congress on Prediabetes and the Metabolic Syndrome
2009 - 2009	Rosiglitazone/Metformin (Avandamet) increases mitochondrial biogenesis in Goto-Kakizaki rats: Bioenergetic consequences for diabetes Conferência	EMBO Lecture Course in Mitochondrial Medicine: from genetics to biological mechanisms and beyond
2009 - 2009	Dibenzofuraninduced mitophagy plays an important role on the inhibition of lung cells proliferation Conferência	EMBO Lecture Course in Mitochondrial Medicine: from genetics to biological mechanisms and beyond
2009 - 2009	Indirubin-3´-oxime prevents hepatic I/R damage by inhibiting GSK-3beta; and mitochondrial permeability transition Conferência	EMBO Lecture Course in Mitochondrial Medicine: from genetics to biological mechanisms and beyond
2009 - 2009	Rosiglitazone/Metformin (Avandamet) increases mitochondrial biogenesis in Goto-Kakizaki rats: Bioenergetic consequences for diabetes Conferência	International Courses on Toxicology: “Mitochondria: between life and death” Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009 - 2009	Dibenzofuraninduced mitophagy plays an important role on the inhibition of lung cells proliferation Conferência	International Courses on Toxicology: “Mitochondria: between life and death” Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009 - 2009	Indirubin-3´-oxime prevents hepatic I/R damage by inhibiting GSK-3beta; and mitochondrial permeability transition Conferência	International Courses on Toxicology: “Mitochondria: between life and death” Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/10/22 - 2008/10/25	Indirubin-3´- oxime prevents hepatic I/R damage by inhibiting GSK-3beta and mitochondrial permeability transition Congresso	XVI National Congress of Biochemistry Universidade dos Açores Centro de Biotecnologia dos Açores, Portugal
2008/10/22 - 2008/10/25	Rosiglitazone/Metformin (Avandamet) increases mitochondrial biogenesis in Goto-Kakizaki rats: Bioenergetic consequences for diabetes Congresso	XVI National Congress of Biochemistry Universidade dos Açores Centro de Biotecnologia dos Açores, Portugal
2008/04/09 - 2008/04/11	Differential alterations in mitochondrial function induced by a choline-deficient diet: understanding fatty liver disease progression Conferência	International Courses on Toxicology 2008 “Metabolic Toxicology: From Pathway to Organism Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/04/09 - 2008/04/11	Exposure to Dibenzofuran affects lung mitochondria bioenergetics and cell proliferation Conferência	International Courses on Toxicology 2008 “Metabolic Toxicology: From Pathway to Organism Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/04/09 - 2008/04/11	Indirubin-3’-oxime impairs mitochondrial oxidative phosphorylation and prevents mitochondrial permeability transition induction Conferência	International Courses on Toxicology 2008 “Metabolic Toxicology: From Pathway to Organism Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/03/16 - 2008/03/20	In vitro assessment of silver nanoparticles toxicity in hepatic mitochondrial function Encontro	47th Annual Meeting of the Society of Toxicology Society of Toxicology, Estados Unidos
2008/02/25 - 2008/02/25	Obesity-related alterations in mitochondrial biogenesis and function: implications for metabolic disease Seminário	Young Scientist Seminar
2007/04/25 - 2007/04/28	Hepatic mitochondrial adenine nucleotide translocator is decreased in Zucker fatty rats: Its potential role for altered mitochondrial bioenergetics in fatty liver disease Congresso	2nd International Congress on "Prediabetes" and the Metabolic Syndrome
2007/04/25 - 2007/04/28	Differential alterations in mitochondrial function induced by a choline-deficient diet: understanding fatty liver disease progression Congresso	2nd International Congress on "Prediabetes" and the Metabolic Syndrome
2007/01/14 - 2007/01/19	Hepatic mitochondrial adenine nucleotide translocator is decreased in Zucker fatty rats: Its potential role for altered mitochondrial bioenergetics in fatty liver disease Conferência	Keystone Symposia on “Obesity: Peripheral and central pathways regulating energy homeostasis”
2006/04/03 - 2006/04/07	Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis Conferência	FEBS Advanced Course “Human and microbial genetics: DNA arrays applied to human parhogens and disease” Federation of European Biochemical Societies, Reino Unido
2006/03/05 - 2006/03/09	Bioenergetic phenotype of NRTI-induced mitochondrial cardiomyopathy Encontro	45th Annual Meeting of the Society of Toxicology Society of Toxicology, Estados Unidos
2006/03/05 - 2006/03/09	Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis Encontro	45th Annual Meeting of the Society of Toxicology Society of Toxicology, Estados Unidos
2006/03/05 - 2006/03/09	Mitochondrial adenine nucleotide translocator expression is decreased in liver cells of Zucker fatty rats: relevance for altered mitochondrial bioenergetics in steatosis Encontro	45th Annual Meeting of the Society of Toxicology Society of Toxicology, Estados Unidos
2005/03/06 - 2005/03/10	Nucleoside analog reverse transcriptase inhibitor (NRTI)-induced mitochondrial depleted cardiac myocytes Encontro	44th Annual Meeting of the Society of Toxicology Society of Toxicology, Estados Unidos
2005/03/06 - 2005/03/10	Hyperglycemia-induced oxidative stress activates the hexosamine pathway and decreases mitochondrial biogenesis Encontro	44th Annual Meeting of the Society of Toxicology Society of Toxicology, Estados Unidos
2004/12/02 - 2004/12/04	Mitochondrial dysfunction as a major determinant in bile acids induced cell death Congresso	XIV Congresso Nacional de Bioquímica Sociedade Portuguesa de Bioquímica, Portugal
2004/03/21 - 2004/03/25	Chenodeoxycholic acid mediates induction of the mitochondrial permeability transition through altered membrane fluidity Encontro	43th Annual Meeting of the Society of Toxicology Society of Toxicology, Estados Unidos
2003/12/04 - 2003/12/06	Hepatic ischemia/reperfusion injury and mitochondrial function: a comparative study between TUDC and silymarin effects Congresso	6th Portuguese Congress on Free Radicals in Chemistry, Biology and Medicine
2003/08/27 - 2003/08/30	Role of mitochondrial dysfunction in combined bile acids-induced cytotoxicity: the switch between apoptosis and necrosis. Conferência	FEBS Advanced Course “Poly-ADP-ribosylation in health and disease” Federation of European Biochemical Societies, Reino Unido
2003/03/09 - 2003/03/13	Mitochondrial mediated cell killing by bile acids Encontro	41st Annual Meeting of the Society of Toxicology Society of Toxicology, Estados Unidos
2003/03/09 - 2003/03/13	Role of mitochondrial dysfunction in combined bile acid-induced apoptosis Encontro	41st Annual Meeting of the Society of Toxicology Society of Toxicology, Estados Unidos
2002/12/05 - 2002/12/07	Potentiation of cell killing by bile acids is mediated by mitochondrial permeability transition induction Congresso	XII Congresso Nacional de Bioquímica Sociedade Portuguesa de Bioquímica, Portugal
2002/09/10 - 2002/09/15	Critical role of mitocondrial protein thiol groups in the inhibitory action of carvedilol on the mitochondrial permeability transition Conferência	12th European Bioenergetics Conference
2002/04/13 - 2002/04/17	Carvedilol: relação entre a actividade antioxidante e inibição da transição de permeabilidade mitocondria Congresso	XXIII Congresso Português de Cardiologia Sociedade Portuguesa de Cardiologia, Portugal
2002/04/13 - 2002/04/17	Mitocôndrias isoladas de cardiomiócitos de ratos com colestase aguda apresentam deficiente acumulação de cálcio Congresso	XXIII Congresso Português de Cardiologia Sociedade Portuguesa de Cardiologia, Portugal
2002/04/13 - 2002/04/17	Colestase crónica e mitocôndrias cardíacas: diminuição da tomada de cálcio por indução da transição de permeabilidade Congresso	XXIII Congresso Português de Cardiologia Sociedade Portuguesa de Cardiologia, Portugal
2002/04/13 - 2002/04/17	A transição de permeabilidade mitocondrial inibe a tomada de cálcio em mitocôndrias cardíacas de ratos diabéticos Congresso	XXIII Congresso Português de Cardiologia Sociedade Portuguesa de Cardiologia, Portugal
2002/04/13 - 2002/04/17	O carvedilol reduz o dano mitocondrial induzido por hipoxantina / xantina oxidase – relevância para a isquémia e reperfusão do miocárdio Congresso	XXIII Congresso Português de Cardiologia Sociedade Portuguesa de Cardiologia, Portugal
2002/04/09 - 2002/04/10	Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism Encontro	Joint Annual Meeting of the Society of Environmental Toxicology & Chemistry, Midwest Chapter & Society of Toxicology, Northland Chapter Society of Environmental Toxicology and Chemistry, Estados Unidos Society of Toxicology, Estados Unidos American College Of Sports Medicine, Estados Unidos Medical Library Association, Estados Unidos
2002/03/17 - 2002/03/21	Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism Encontro	41st Annual Meeting of the Society of Toxicology Society of Toxicology, Estados Unidos
2001/09/27 - 2001/09/29	Mitochondria from diabetic rats’ cardiomyocytes are more resistant to the induction of the permeability transition pore Encontro	2nd European Meeting on Vascular Biology and Medicine
2001/09/02 - 2001/09/07	Chenodeoxycholate induced-mitochondrial dysfunction involves induction of the permeability transition pore: protective effect of carvedilol Conferência	FEBS Advanced Course “Mitochondrial Role in the Cell Life and Death” Federation of European Biochemical Societies, Reino Unido
2001/09/02 - 2001/09/07	Carvedilol inhibits the high conductance state of the permeability transition pore in heart mitochondria carvedilol Conferência	FEBS Advanced Course “Mitochondrial Role in the Cell Life and Death” Federation of European Biochemical Societies, Reino Unido
2001/05/25 - 2001/05/29	Chenodeoxycholate induced-mitochondrial dysfunction involves induction of the permeability transition pore: protective effect of carvedilol Encontro	40th Annual Meeting of the Society of Toxicology Society of Toxicologic Pathology, Estados Unidos
2000/11/09 - 2000/11/11	Decreased susceptibility of heart mitochondria from diabetic GK rats to mitochondrial permeability transition induced by calcium/phosphate Congresso	II Congresso de Investigação em Bioquímica
2000/09/28 - 2000/09/30	Chenodeoxycholate is a potent inducer of the permeability transition pore in liver mitochondria: its importance in cholestasis development Congresso	XII Congresso Nacional de Bioquímica Sociedade Portuguesa de Bioquímica, Portugal
2000/09/28 - 2000/09/30	Carvedilol inhibits the exogenous NADH dehydrogenase in rat heart mitochondria Congresso	XII Congresso Nacional de Bioquímica Sociedade Portuguesa de Bioquímica, Portugal
2000/09/28 - 2000/09/30	Carvedilol in heart mitochondria: protonophore or opener of the mitochondrial KATP channels? Congresso	XII Congresso Nacional de Bioquímica Sociedade Portuguesa de Bioquímica, Portugal
2000/09/28 - 2000/09/30	Inhibitory effect of carvedilol in the high-conductance state of the calcium-sensitive mitochondrial permeability transition pore Congresso	XII Congresso Nacional de Bioquímica Sociedade Portuguesa de Bioquímica, Portugal
2000/04/09 - 2000/04/12	O carvedilol inibe a NADH desidrogenase exógena em mitocôndrias de coração de rato Congresso	XXI Congresso Português de Cardiologia Sociedade Portuguesa de Cardiologia, Portugal
2000/04/07 - 2000/04/12	Impairment of mitochondrial function induced by bile acids: relevance for bile acid therapy Conferência	Mechanisms in Toxicity: EuroConference on New Cellular Targets of Cytotoxic Mechanisms European Science Foundation, França
2000/04/08 - 2000/04/11	Os cardiomiócitos de ratos diabéticos são mais resistentes à indução da transição de permeabilidade mitocondrial Congresso	XXII Congresso Português de Cardiologia Sociedade Portuguesa de Cardiologia, Portugal
2000/03/19 - 2000/03/23	Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy Congresso	39th Annual Meeting of the Society of Toxicology
2000/03/05 - 2000/03/10	Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy Conferência	Expression and regulation of mitochondrial oxidative phosphorylation and disorders in human pathology Federation of European Biochemical Societies, Reino Unido
2000/03/05 - 2000/03/10	Carvedilol inhibits the exogenous NADH dehydrogenase in rat heart mitochondria Conferência	FEBS Advanced Course “Expression and regulation of mitochondrial oxidative phosphorylation and disorders in human pathology” Federation of European Biochemical Societies, Reino Unido

Júri de grau académico

	Tema Tipo de participação	Nome do candidato (Tipo de grau) Instituição / Organização
2020	Avaliação do sistema colinérgico na doença de Alzheimer	António José dos Santos Gabriel (Doutoramento) Universidade de Coimbra, Portugal
2020	Mitochondrial dynamics and mitophagy in cellular models of Parkinson's Disease Presidente do júri	Bruno Miguel Sequeira dos Santos (Mestrado)
2020	Heavy Metal Exposure And Its Effects In Male Reproductive Health: An In Vivo And In Vitro Study Arguente principal	Carolina Matos Carola (Mestrado)
2020	Biological activity of Brassica by-products in cell models of oxidative stress and lipid toxicity Arguente principal	José Pedro Fernandes Castelão Moreira Baptista (Mestrado)
2020	Metabolic modulation in paused-like pluripotency Vogal	Maria Inês Ramalho de Almeida e Sousa (Doutoramento)
2019	Understanding the underlying mechanisms regulating aging and longevity	João Filipe Alves Amorim (Doutoramento) Universidade de Coimbra, Portugal
2019	Illuminating G protein-coupled receptors: a bioluminescence-based method to photoactivate receptor ligands	Ana Carolina Palmeira do Amaral (Mestrado) Universidade de Coimbra, Portugal
2019	P-cadherin role on the mitochondrial biology of breast cancer cells	Margarida Ribeiro da Silva (Mestrado) Universidade de Coimbra, Portugal
2019	Mitochondrial performance during osteoblast differentiation: searching new targets to counteract osteoporosis	Sara Cristiana Alves Valente (Mestrado)
2019	Modulation of complex I and oxidative capacity in cells under metabolic stress: the interplay between miR-378a-3p and metformin	Ivo Manuel Ferreira Machado (Mestrado) Universidade de Coimbra, Portugal
2019	Effect of dual therapy with liraglutide and ghrelin on brain metabolism and intracellular stress in the Huntington's disease R6/2 mouse model	Débora Tatiana de Sousa Mena (Mestrado) Universidade de Coimbra, Portugal
2019	Role of the Adenine Nucleotide Translocator 2 in P19 Embryonal Carcinoma Stem Cells Mitochondrial Profile	Gabriela Lopes Oliveira (Mestrado) Universidade de Coimbra, Portugal
2019	Uncover the mechanism behind miRNA function on cell survival	Marta Filipa Viegas Barão (Mestrado) Universidade de Coimbra, Portugal
2018/09/12	Investigation of genes associated to mitochondrial import and post-translational processing in LHON	Márcia Joana Nascimento Teixeira (Mestrado) Universidade de Coimbra, Portugal
2018	Liver transplantation: new prognostic factors of the regulation of mitochondrial function in ischemia/reperfusion	Rui Miguel Rua Filipe Martins (Doutoramento) Universidade de Coimbra, Portugal
2017/07/18	O-GlcNAcylation represents a “sweet” route to tackle Alzheimer’s disease-related phenotype	Tiffany Santos Pinho (Mestrado) Universidade de Coimbra, Portugal
2017/07/17	Neuronal energy status and Alzheimer's disease: searching for a connection	Diogo Miguel Matos Vila Verde (Mestrado) Universidade de Coimbra, Portugal
2017	O papel do sistema adenosinérgico em modelos animais de estresse crónico e depressão	Nuno Miguel de Jesus Machado (Doutoramento) Universidade de Coimbra, Portugal
2017	O-GlcNAcylation represents a “sweet” route to tackle Alzheimer’s disease-related phenotype	Tiffany Santos Pinho (Mestrado) Universidade de Coimbra, Portugal
2016/11/17	Modulatory effect of dietary pattern, exercise and atorvastatin treatment on eNos, sirtuins and miR-155 expression in the erectile tissue of the aged rat	Bárbara Sofia Ferreira da Rocha (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2016	Functional investigation of OXPHOS assembly factors in Leber's Hereditary optic Neuropathy (LHON)	Maria Inês Arêlo Manso da Fonseca (Mestrado) Universidade de Coimbra, Portugal
2016	Efeito da cirurgia bariática na função endotelial associada à diabetes tipo 2	Diana Cristina Miguel Ribeiro (Mestrado) Universidade de Coimbra, Portugal
2016	Avaliação dos mecanismos moleculares de resistência a hipometilantes em Leucemia Mieloide Aguda	Patrícia Isabel Martins Corredeira (Mestrado) Universidade de Coimbra, Portugal
2016	Endothelial cell's response to proteostatic dysregulation: pursuing the protective action of ghrelin	Daniela Alexandra Dinis Costa (Mestrado) Universidade de Coimbra, Portugal
2016	The importance of cytokinesmediated communication in CSCs’ formation	Marco Rafael Lopes da Cunha (Mestrado) Universidade de Coimbra, Portugal
2016	Functional investigation of OXPHOS assembly factors in Leber's Hereditary optic Neuropathy (LHON	Maria Ine^s Are^lo Manso da Fonseca (Mestrado) Universidade de Coimbra, Portugal
2016	Efeito da cirurgia baria´tica na func¸a~o endotelial associada a` diabetes tipo 2	Diana Cristina Miguel Ribeiro (Mestrado) Universidade de Coimbra, Portugal
2016	Avaliac¸a~o dos mecanismos moleculares da resiste^ncia a hipometilantes em Leucemia Mieloide Aguda	Patri´cia Isabel Martins Corredeira (Mestrado) Universidade de Coimbra, Portugal
2016	Endothelial cell's response to proteostatic dysregulation: pursuing the protective action of ghrelin	Daniela Alexandra Dinis Costa (Mestrado) Universidade de Coimbra, Portugal
2016	The importance of cytokines-mediated communication in CSCs' formation	Marco Rafael Lopes da Cunha (Mestrado) Universidade de Coimbra, Portugal
2016	Modulatory effect of dietary pattern, exercise, and atorvastatin treatment on eNOS, sirtuins and miR-155 expression in the erectile tissue of the aged rat	Ba´rbara Sofia Ferreira da Rocha (Mestrado) Universidade do Porto, Portugal
2015/09/11	Effects of vitamin D deficient and high-fat diets in the diabetic brain: focus on insulin signaling	Guilherme Alvarinhas de Assis Loureiro (Mestrado) Universidade de Coimbra, Portugal
2015/07/14	Doxorubicin cardiotoxicity: Metabolic landscaping of the epigenome	André de Melo Ferreira (Mestrado) Universidade de Coimbra, Portugal
2015	Mitochondria-directed antioxidants as anticancer agents	Katia Queirós Fernandes dos Santos (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015	Effects of vitamin D deficient and high-fat diets in the diabetic brain: focus on insulin signaling Arguente	Guilherme Alvarinhas de Assis Loureiro (Mestrado) Universidade de Coimbra, Portugal
2015	Mitochondrial-directed antioxidants as anti-cancer agents	Katia Queiro´s Fernandes dos Santos (Mestrado) Universidade de Coimbra, Portugal
2015	Doxorubicin cardiotoxicity: Metabolic landscaping of the epigenome	Andre´ de Melo Ferreira (Mestrado) Universidade de Coimbra, Portugal
2015	Energia para a Regeneração Hepática:Bioenergética Mitocondrial e a Patogénese da Insuficiência Hepática Pós-Hepatectomia	Henrique Miguel Marques Bom Borges Alexandrino (Doutoramento) Universidade de Coimbra Faculdade de Medicina, Portugal

Comissão de avaliação

	Descrição da atividade Tipo de assessoria	Instituição / Organização
2019 - 2019	''Research Projects'' Call Avaliador	Hrvatska Zaklada za Znanost, Croácia
2017 - 2017	Grant proposal reviewer Avaliador	Prinses Beatrix Spierfonds, Países Baixos
2017 - 2017	25o Concurso Jovens Cientistas e Investigadores - Mostra Nacional de Cie^ncia – Porto 2017 Avaliador
2016 - 2016	Cooperação Transnacional Hungria, Fundação para a Ciência e a Tecnologia Avaliador
2016 - 2016	''Research Projects'' Call Avaliador	Hrvatska Zaklada za Znanost, Croácia
2015 - 2015	Concurso FCT de Bolsas individuais 2015 - PAINEL DE BIOMEDICINA E MEDICINA BÁSICA Avaliador	Fundação para a Ciência e a Tecnologia, Portugal
2015 - 2015	Concurso FCT de Bolsas individuais 2015 - PAINEL DE BIOMEDICINA E MEDICINA BÁSICA - Audiências Prévias - 2015 Avaliador	Fundação para a Ciência e a Tecnologia, Portugal
2014 - 2014	Concurso FCT de Bolsas individuais 2014 - PAINEL DE BIOMEDICINA E MEDICINA BÁSICA Avaliador	Fundação para a Ciência e a Tecnologia, Portugal
2014 - 2014	Concurso FCT de Bolsas individuais 2014 - PAINEL DE BIOMEDICINA E MEDICINA BÁSICA - Audiências Prévias Avaliador	Fundação para a Ciência e a Tecnologia, Portugal

Curso / Disciplina lecionado

	Disciplina	Curso (Tipo)
2019 - Atual	Fisiologia Celular	(Licenciatura)
2015 - Atual	Laboratórios de Biologia Molecular	(Licenciatura)
2015 - Atual	Toxicidade e Doença	(Mestrado)
2015 - 2019	Fisiologia Humana	(Licenciatura)

Entrevista (jornal / revista)

	Descrição da atividade	Jornal / Forum
2019	Entrevista - Mulheres e Ciência. Faces de Eva. Estudos sobre a Mulher	Faces de Eva

Membro de associação

	Nome da associação	Tipo de participação
2018 - Atual	Toxicology and Applied Pharmacology -corpo editorial
2014 - Atual	Toxicology Mechanisms and Methods -corpo editorial	Corpo editorial de publicação periódica
2012 - Atual	European Association for the Study of Diabetes
2000 - Atual	Sociedade Portuguesa de Bioquímica

Distinções

Outra distinção

2007	L’Oréal for Women in Science
1999	Premio Escolar Avelar Brotero Universidade de Coimbra, Portugal
1998	Bolsa de Estudo por Merito Universidade de Coimbra, Portugal
1997	Bolsa de Estudo por Merito Universidade de Coimbra, Portugal