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Catarina got her PhD in Biomedical Sciences (ICBAS/UP) in 2017 and is currently an Associate Researcher at the Nanomedicine at the Translational Drug Delivery Group, Instituto de Investigação e Inovação em Saúde (I3S), were she leads a team on advanced modelling of musculoskeletal pediatric tumors. Currently she coordinates two projects on the development of a bioengineered 3D model of osteosarcoma, aiming at providing a tool to unravel tumor development, the metastatic process and to screen in a biologically relevant setting novel therapies and targeted nanomedicines. Catarina has been working in the biomedical engineering field for 15 years, being involved in multiple projects in the area of nanotechnology, immunomodulation, musculoskeletal disorders and disease in vitro modelling. She has participated in 10 international and national projects during her career (DISC REGENERATION, RESTORE, GENEGUT, DUO-DIO, EUROSPINE, among others). She has vast national/international network of collaborators from academia (i3S (other research groups), University of Oulu, Shanghai Jiao Tong University School of Medicine, and industry (FINNADVANCE, React4Life). Through her scientific path, Catarina has published 39 articles, displaying a h-index of 19 (source: scopus). She has participated in multiple dissemination actions (>30 participations) both in national and international conferences, building up her reputation and recognition by her peers, as can be perceived by the high number of citations (>1000) and invitations to act as an expert panel reviewer for international funding agencies, examiner, lecturer, invited speaker and integration of scientific and PhD Advisory committees. Catarina has supervised 4 trainees (BSc), 6 master students (two ongoing) and is currently supervising 3 PhD students. Her responsibility towards the scientific endeavor has not been restricted to research, she actively participates in public awareness actions for science dissemination in primary and secondary schools and exhibitions to general population. Catarina has contributed to secure funding of the Liga Portuguesa Contra o Cancro (15K euros) and FCT (50k euros) as Principal Investigator (PI), from Gilead Genese Program (35K euros) as co-PI and from the European Commission (H2020 RESTORE (5.4M Euros) and HORIZON-HLTH-2021-TOOL-06 GENEGUT (4.9M Euros) as a team member. Catarina has been recently elected SPLC-CRS Board Director (2024-2026) and is the vice-chair of the Nanotechnologies for Regenerative Medicine Working group of ETPN (European Technology Platform of Nanomedicines).
Identificação

Identificação pessoal

Nome completo
Ana Catarina Leite Pereira

Nomes de citação

  • Leite Pereira, Catarina

Identificadores de autor

Ciência ID
AA1B-AB56-F09A
ORCID iD
0000-0001-8703-1245

Endereços de correio eletrónico

  • catarina.pereira@i3s.up.pt (Profissional)

Telefones

Telefone
  • (351) 226074900 (Profissional)

Moradas

  • I3S/INEB . Rua Alfredo Allen, 208 , 4200-135, Porto, Porto, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Clínica - Oncologia
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biotecnologia Aplicada à Saúde
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo
  • Ciências Naturais - Ciências Biológicas - Microbiologia
  • Ciências Médicas e da Saúde - Outras Ciências Médicas

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Francês Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2024/10/17 - 2024/12/06
Concluído
Building and Leading Research Teams (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/01/24 - 2023/01/24
Concluído
Data Management Plan & FAIR data management – from plan to practice (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/11/24 - 2022/11/24
Concluído
Course on Life Science Intellectual Property: Management and Exploitation, 1st edition (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020 - 2021
Concluído
Research Ethics & Integrity Course (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
N/A
2020
Frequentou
Workshop: Organoids and Advanced 3D in Vitro Models for Research in Health and Disease (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019
Frequentou
Advanced Course in Flow Cytometry: From basic knowledge to advanced applications (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
N/A
2017/07/19
Concluído
Ciências Biomédicas (Doutoramento)
Universidade do Porto, Portugal
"MESENCHYMAL STEM/STROMAL CELLS RECRUITMENT FOR INTERVERTEBRAL DISC REGENERATION" (TESE/DISSERTAÇÃO)
Aprovada com Distinção
2017
Concluído
6th Advanced Summer School: Interrogations at the Biointerface - Research/Clinical Interface at the Spine (Outros)
Instituto Nacional de Engenharia Biomédica, Portugal
N/A
2015
Concluído
5th Advanced Summer School - The Nano/medicine interface (Outros)
Instituto Nacional de Engenharia Biomédica, Portugal

Institut de Bioenginyeria de Catalunya, Espanha
2013
Concluído
3rd Advanced Summer School - Interrogations at the Biointerface: Inflammation/Repair Interface (Outros)
Instituto Nacional de Engenharia Biomédica, Portugal

Institut de Bioenginyeria de Catalunya, Espanha
N/A
2010
Concluído
Engenharia Biomédica (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
"Biosynthesis of Poly-gamma-Glutamic Acid and its application in Chitosan/gamma-PGA " (TESE/DISSERTAÇÃO)
17
2009
Concluído
1st Advanced Summer School Interrogations at the Biointerface - Cancer/Regeneration Interface (Outros)
Instituto Nacional de Engenharia Biomédica, Portugal

Institut de Bioenginyeria de Catalunya, Espanha
N/A
2008
Concluído
Biologia (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"n/a" (TESE/DISSERTAÇÃO)
14 (Classe c)
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2022/03/01 - Atual Investigador Auxiliar (carreira) (Investigação) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/02/16 - 2023/02/28 Assistente de Investigação (carreira) (Investigação) Instituto Nacional de Engenharia Biomédica, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018/06/01 - 2019/12/31 Assistente de Investigação (carreira) (Investigação) Instituto Nacional de Engenharia Biomédica, Portugal
2017/10/01 - 2018/06/30 Pós-doutorado (Investigação) Instituto Nacional de Engenharia Biomédica, Portugal
2017/03/01 - 2017/08/31 Investigador (Investigação) Instituto Nacional de Engenharia Biomédica, Portugal
2012/01/04 - 2012/12/19 Investigador visitante (Investigação) AO Research Institute Davos, Suiça
AO Research Institute Davos, Suiça
2008/12/28 - 2011/12/31 Investigador (Investigação) Instituto Nacional de Engenharia Biomédica, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2017/09/01 - 2019/12/31 Doctoral Programme Managment Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
(...)
2013/03/01 - 2017/02/28 PhD Student Instituto Nacional de Engenharia Biomédica, Portugal
Instituto Nacional de Engenharia Biomédica, Portugal
(...)
Projetos

Bolsa

Designação Financiadores
2013/03/01 - 2017/02/28 FCT PhD Fellowship: Mesenchymal stem/stromal cells recruitment for invertebral disc regeneration
SFRH/BD/85779/2012
Bolseiro de Doutoramento
Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Associação para a Inovação e Desenvolvimento da FCT
Concluído

Projeto

Designação Financiadores
2022/06 - Atual LITWIN - Crohn’s & Colitis Foundation Research
Litwin
Investigador
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Em curso
2022/01/01 - Atual HORIZON-HLTH-2021-TOOL-06: GENEGUT - Oral delivery of encapsulated RNA nanotherapeutics for targeted treatment of ileal Crohn's disease
GENEGUT 101057491
Investigador
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
European Comission
Em curso
2021 - Atual GILEAD GENESE: DUO-DIU Dispositivo intrauterino para co-libertação de levonorgestrel e de dapivirina
Gilead GÉNESE
Investigador
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Em curso
2023/12/23 - 2025/05/23 MICKEY - Modelling osteosarcoma In vitro: a novel on-Chip platform to unravel KEY mechanisms of lung metastasis towards new therapies development and screening
2023.0009
Investigador responsável
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2022/11/30 - 2023/11/30 Liga Portuguesa Contra o Cancro (LPCC): B2Tek-4OS - Bio-inspired and Bioengineered Technology for OSteosarcoma, unraveling OS to advance in novel targeted therapies
NN 2023-25 CP
Investigador responsável
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Liga Portuguesa Contra o Cancro
Em curso
2020/02/16 - 2022/10 H2020: RESTORE - User-centred smart 3D nanobiomaterial-based scaffold for chondral repair
Investigador
Instituto Nacional de Engenharia Biomédica, Portugal
European Comission
Em curso
2019/01/01 - 2019/12/31 Instituto de Investigação e Inovação em Saúde
UID/BIM/04293/2019
Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2017/03 - 2019/12/31 Norte-01-0145-FEDER-000012: Bioengineered Therapies for infectious diseases and tissue regeneration
Norte-01-0145-FEDER-000012
Investigador Pós-doutorado
Instituto Nacional de Engenharia Biomédica, Portugal
N/A
Concluído
2017 - 2018/12/01 EUROSPINE Task Force 2017: Disc Regeneration, Immuno- and Neuro- modulation
EUROSPINE_5_2017
Bolseiro de Investigação
Instituto Nacional de Engenharia Biomédica, Portugal
EUROSPINE The Spine Society of Europe
Concluído
2015/07/27 - 2016/07/14 EUROSPINE Task Force 2015: Stem cells paracrine action for intervertebral disc regeneration
EUROSPINE TRF_2015
Investigador
Instituto Nacional de Engenharia Biomédica, Portugal
Concluído
2012/01/01 - 2013/12/31 AO SPINE: Mesenchymal stem/stromal cells recruitment for intervertebral disc regeneration
AOSRN-104979
Bolseiro de Doutoramento
AO Research Institute Davos, Suiça

Instituto Nacional de Engenharia Biomédica, Portugal
AOSpine International
Concluído
2008/12/28 - 2012/12/31 FP7 DISC DEGENERATION: Novel biofunctional high porous polymer scaffolds and techniques controlling angiogenesis for the regeneration and repair of the degenerated intervertebral disc
213904
Bolseiro de Investigação
European Commission Seventh Framework Programme for Research and Technological Development
Concluído
Produções

Publicações

Artigo em conferência
  1. Pereira, Ana Catarina Leite; R. Madeira Gonçalves; Peroglio, M.; G. Pattappa; D. Eglin; M. Adolfo Barbosa; M. Alini; Grad, S.. "Stromal Cell-Derived Factor-1 Delivery System: A New Approach for the Recruitment of Mesenchymal Stem Cells in Degenerating Intervertebral Disc". Trabalho apresentado em Global Spine Congress, 2014.
    Publicado • 10.1055/s-0034-1376645
  2. Inês Odila; Pereira, Ana Catarina Leite; Molinos, Maria; R. M. Gonçalves; M. A. Barbosa. "An In Situ Anti-Inflammatory Drug Delivery System for Intervertebral Disks". Trabalho apresentado em Global Spine Congress, Helsínquia, 2012.
    Publicado
  3. Leite Pereira, Catarina; Gonçalves, Raquel Madeira; Dr. Frederico Ferreira-da-Silva; Antunes, Joana C.; Molinos, Maria; Barbosa, Mário Adolfo. Autor correspondente: Barbosa, Mário Adolfo. "Biosynthesis of poly-gamma-glutamic acid and its application in the development of chitosan/poly-gamma-glutamic acid nanoparticles for drug delivery". Trabalho apresentado em 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials, Dublin, 2011.
    Publicado
Artigo em revista
  1. Barbara Ferreira; Cecilia Ferreira; Claudia Martins; Rute Nunes; José das Neves; Leite Pereira, Catarina; Sarmento, Bruno. "Establishment of a 3D Multi-layered In Vitro Model of Inflammatory Bowel Disease". Journal of Controlled Release (2024):
    Acesso aberto • Aceite para publicação
  2. Sofia Costa; João Rodrigues; Carolina Vieira; Sofia Dias; Juliana Viegas; Bruno Sarmento; Leite Pereira, Catarina. Autor correspondente: Leite Pereira, Catarina. "Advancing osteosarcoma 3D modeling in vitro for novel tumor microenvironment-targeted therapies development". Journal of Controlled Release (2024): https://doi.org/10.1016/j.jconrel.2024.10.068.
    Aceite para publicação • https://doi.org/10.1016/j.jconrel.2024.10.068
  3. Viegas, Juliana; Sofia Costa; Sofia Dias; Leite Pereira, Catarina; Sarmento, Bruno. "Patient-Derived Melanoma Immune-Tumoroids as a Platform for Precise High throughput Drug Screening". Advanced Science (2024): https://onlinelibrary.wiley.com/doi/10.1002/advs.202408707.
    Acesso aberto • Publicado • 10.1002/advs.202408707
  4. Marina Couto; Daniela Pereira Vasconcelos; Catarina Leite Pereira; Estrela Neto; Bruno Sarmento; Meriem Lamghari. "Neuro-Immunomodulatory Potential of Nanoenabled 4D Bioprinted Microtissue for Cartilage Tissue Engineering". Advanced Healthcare Materials (2024): https://doi.org/10.1002/adhm.202400496.
    10.1002/adhm.202400496
  5. Cai, Zhengwei; Chen, Zhijie; Tang, Yuan; Cheng, Liang; Qiu, Minglong; Wang, Ningtao; Jiang, Wei; et al. "Bioinspired Bone Seed 3D-Printed Scaffold via Trapping Black Phosphorus Nanosheet for Bone Regeneration". Small Science (2024): http://dx.doi.org/10.1002/smsc.202300357.
    10.1002/smsc.202300357
  6. Daniela Pereira Vasconcelos; Catarina Leite Pereira; Marina Couto; Estrela Neto; Beatriz Ribeiro; Filipe Albuquerque; Alexandra Freitas; et al. "Nanoenabled Immunomodulatory Scaffolds for Cartilage Tissue Engineering". Advanced Functional Materials (2024): https://doi.org/10.1002/adfm.202400627.
    10.1002/adfm.202400627
  7. Ferreira, Bárbara; Barros, Andreia S.; Leite Pereira, Catarina; Viegas, Juliana; das Neves, José; Nunes, Rute; Sarmento, Bruno. "Trends in 3D models of inflammatory bowel disease". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2024): 167042. http://dx.doi.org/10.1016/j.bbadis.2024.167042.
    Publicado • 10.1016/j.bbadis.2024.167042
  8. Leite Pereira, Catarina; Grad, Sibylle; Gonçalves, Raquel M.. "Biomarkers for intervertebral disc and associated back pain: From diagnosis to disease prognosis and personalized treatment". JOR SPINE 6 4 (2023): http://dx.doi.org/10.1002/jsp2.1280.
    10.1002/jsp2.1280
  9. Qimanguli Saiding; Yiyao Chen; Juan Wang; Catarina Leite Pereira; Bruno Sarmento; Wenguo Cui; Xinliang Chen. "Abdominal wall hernia repair: from prosthetic meshes to smart materials". Materials Today Bio (2023): https://doi.org/10.1016/j.mtbio.2023.100691.
    10.1016/j.mtbio.2023.100691
  10. Domingues, Mariana; Leite Pereira, Catarina; Sarmento, Bruno; Castro, Flávia. "Mimicking 3D breast tumor-stromal interactions to screen novel cancer therapeutics". European Journal of Pharmaceutical Sciences (2023): 106560. http://dx.doi.org/10.1016/j.ejps.2023.106560.
    10.1016/j.ejps.2023.106560
  11. Carvalho, Suzana; Silveira, Maria José; Domingues, Mariana; Ferreira, Bárbara; Leite Pereira, Catarina; PalmiraGremião, Maria; Sarmento, Bruno. "Multicellular Quadruple Colorectal Cancer Spheroids as an In Vitro Tool for Anti-angiogenic Potential Evaluation of Nanoparticles". Advanced Therapeutics (2023): 2200282. http://dx.doi.org/10.1002/adtp.202200282.
    10.1002/adtp.202200282
  12. Catarina Leite Pereira; Meriem Lamghari; Bruno Sarmento. "Advances in nanoenabled 3D matrices for cartilage repair". Acta Biomaterialia (2022): https://doi.org/10.1016/j.actbio.2022.07.033.
    10.1016/j.actbio.2022.07.033
  13. Baião, Ana; Dias, Sofia; Soares, Ana Francisca; Leite Pereira, Catarina; Oliveira, Carla; Sarmento, Bruno. "Advances in the use of 3D colorectal cancer models for novel drug discovery". Expert Opinion on Drug Discovery 17 6 (2022): 569-580. http://dx.doi.org/10.1080/17460441.2022.2056162.
    10.1080/17460441.2022.2056162
  14. Neto, Estrela; Monteiro, Ana Carolina; Pereira, Catarina Leite; Simões, Miguel; Conde, João Pedro; Chu, Virginia; Sarmento, Bruno; Lamghari, Meriem. "Micropathological chip modelling the neurovascular unit response to inflammatory bone condition". Advanced Healthcare Materials (2022): 2102305. http://dx.doi.org/10.1002/adhm.202102305.
    Publicado • 10.1002/adhm.202102305
  15. Rodrigues, João; Sarmento, Bruno; Pereira, Catarina Leite. "Osteosarcoma tumor microenvironment: the key for the successful development of biologically relevant 3D in vitro models". In vitro models (2022): http://dx.doi.org/10.1007/s44164-022-00008-x.
    10.1007/s44164-022-00008-x
  16. Jiang, Wei; Hou, Fushan; Gu, Yong; Saiding, Qimanguli; Bao, Pingping; Tang, Jincheng; Wu, Liang; et al. "Local bone metabolism balance regulation via double-adhesive hydrogel for fixing orthopedic implants". Bioactive Materials 12 (2021): 169-184. http://dx.doi.org/10.1016/j.bioactmat.2021.10.017.
    10.1016/j.bioactmat.2021.10.017
  17. Cunha, Carla; Leite Pereira, Catarina; Ferreira, Joana R.; Ribeiro-Machado, Cláudia; Grad, Sibylle; Santos, Susana G.; Gonçalves, Raquel M.. "Therapeutic Strategies for IVD Regeneration through Hyaluronan/SDF-1-Based Hydrogel and Intravenous Administration of MSCs". International Journal of Molecular Sciences 22 17 (2021): 9609. http://dx.doi.org/10.3390/ijms22179609.
    10.3390/ijms22179609
  18. Flávia Castro; Catarina Leite Pereira; Maria Helena Macedo; Andreia Almeida; Maria José Silveira; Sofia Dias; Ana Patrícia Cardoso; et al. "Advances on colorectal cancer 3D models: The needed translational technology for nanomedicine screening". Advanced Drug Delivery Reviews 175 (2021): 113824-113824. https://doi.org/10.1016/j.addr.2021.06.001.
    No prelo • 10.1016/j.addr.2021.06.001
  19. Castro, Flávia; Leite Pereira, Catarina; Macedo, Maria Helena; Almeida, Andreia; Silveira, Maria José; Cardoso, Ana Patricia; Oliveira, Maria José; Sarmento, Bruno. "Advances in Colorectal cancer 3D models: the needed translational technology for nanomedicine screening". Advanced Drug Delivery Reviews (2021):
    Aceite para publicação
  20. Ferreira, Joana Rita; Quelhas Teixeira, Graciosa; Neto, Estrela; Ribeiro-Machado, Cláudia; Silva, Andreia Machado; Caldeira, Joana; Leite Pereira, Catarina; et al. "IL-1ß-pre-conditioned Mesenchymal Stem/stromal Cells’ secretome modulates the inflammatory response and aggrecan deposition in intervertebral disc". eCells & Materials 41 (2021): 431-543. http://dx.doi.org/10.22203/ecm.v041a28.
    Aceite para publicação • 10.22203/ecm.v041a28
  21. Castro, Flávia; Martins, Cláudia; Silveira, Maria José; Moura, Rui Pedro; Leite Pereira, Catarina; Sarmento, Bruno. "Advances on erythrocyte-mimicking nanovehicles to overcome barriers in biological microenvironments". Advanced Drug Delivery Reviews 170 (2021): 312-339. http://dx.doi.org/10.1016/j.addr.2020.09.001.
    10.1016/j.addr.2020.09.001
  22. Castro, Flávia; Pinto, Marta L.; Pereira, Catarina L.; Serre, Karine; Barbosa, Mário A.; Vermaelen, Karim; Gärtner, Fátima; et al. "Chitosan/¿-PGA nanoparticles-based immunotherapy as adjuvant to radiotherapy in breast cancer". Biomaterials 257 (2020): 120218. http://dx.doi.org/10.1016/j.biomaterials.2020.120218.
    10.1016/j.biomaterials.2020.120218
  23. Xu, Yichang; Gu, Yong; Cai, Feng; Xi, Kun; Xin, Tianwen; Tang, Jincheng; Wu, Liang; et al. "Metabolism Balance Regulation via Antagonist-Functionalized Injectable Microsphere for Nucleus Pulposus Regeneration". Advanced Functional Materials 30 52 (2020): 2006333. http://dx.doi.org/10.1002/adfm.202006333.
    10.1002/adfm.202006333
  24. Teixeira, José H.; Pereira, Catarina Leite; Almeida, Maria Inês; Teixeira, Graciosa Q.; Gonçalves, Raquel M.; Barbosa, Mário A.; Santos, Susana G.. "Articular Repair/Regeneration in Healthy and Inflammatory Conditions: From Advanced In Vitro to In Vivo Models". Advanced Functional Materials 30 44 (2020): 1909523. http://dx.doi.org/10.1002/adfm.201909523.
    10.1002/adfm.201909523
  25. Cunha, Carla; Q. Teixeira, Graciosa; Ribeiro-Machado, Cláudia; Leite Pereira, Catarina; Ferreira, Joana R.; Molinos, Maria; G. Santos, Susana; Barbosa, Mário A.; M. Goncalves, Raquel. "Modulation of the In Vivo Inflammatory Response by Pro- Versus Anti-Inflammatory Intervertebral Disc Treatments". International Journal of Molecular Sciences 21 5 (2020): 1730. http://dx.doi.org/10.3390/ijms21051730.
    10.3390/ijms21051730
  26. Flávia Castro; Marta L. Pinto; Rui Almeida; Flávia Pereira; Andreia M. Silva; Leite Pereira, Catarina; Susana G. Santos; et al. "Chitosan/poly(¿-glutamic acid) nanoparticles incorporating IFN-¿ for immune response modulation in the context of colorectal cancer". Biomaterials Science 7 8 (2019): 3386-3403. http://dx.doi.org/10.1039/c9bm00393b.
    10.1039/c9bm00393b
  27. Leite Pereira, Catarina; Quelhas Teixeira, Graciosa; Rita Ferreira, Joana; D'Este, Matteo; Eglin, David; Alini, Maulo; Grad, Sibylle; Barbosa, Mário Adolfo; Gonçalves, Raquel Madeira. "Stromal Cell Derived Factor-1-Mediated Migration of Mesenchymal Stem Cells Enhances Collagen Type II Expression in Intervertebral Disc". Tissue Engineering Part A 24 23-24 (2018): 1818-1830. http://dx.doi.org/10.1089/ten.tea.2018.0131.
    10.1089/ten.tea.2018.0131
  28. Teixeira, Graciosa Q.; Pereira, Catarina Leite; Ferreira, Joana R.; Maia, André F.; Gomez-Lazaro, Maria; Barbosa, Mário A.; Neidlinger-Wilke, Cornelia; Goncalves, Raquel M.. "Immunomodulation of Human Mesenchymal Stem/Stromal Cells in Intervertebral Disc Degeneration". SPINE 43 12 (2018): E673-E682. http://dx.doi.org/10.1097/brs.0000000000002494.
    10.1097/brs.0000000000002494
  29. Antunes, J.C.; Pereira, C.L.; Teixeira, G.Q.; Silva, R.V.; Caldeira, J.; Grad, S.; Gonçalves, R.M.; Barbosa, M.A.. "Poly(¿-glutamic acid) and poly(¿-glutamic acid)-based nanocomplexes enhance type II collagen production in intervertebral disc". Journal of Materials Science: Materials in Medicine 28 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-84996606963&partnerID=MN8TOARS.
    10.1007/s10856-016-5787-1
  30. Castro, F.; Pinto, M.L.; Silva, A.M.; Leite Pereira, Catarina; Teixeira, G.Q.; Gomez-Lazaro, M.; Santos, S.G.; et al. "Pro-inflammatory chitosan/poly(¿-glutamic acid) nanoparticles modulate human antigen-presenting cells phenotype and revert their pro-invasive capacity". Acta Biomaterialia 63 (2017): 96-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-85030032238&partnerID=MN8TOARS.
    10.1016/j.actbio.2017.09.016
  31. Cunha, C.; Almeida, C.R.; Almeida, M.I.; Silva, A.M.; Molinos, M.; Lamas, S.; Pereira, C.L.; et al. "Systemic delivery of bone marrow mesenchymal stem cells for in situ intervertebral disc regeneration". Stem Cells Translational Medicine 6 3 (2017): 1029-1039. http://www.scopus.com/inward/record.url?eid=2-s2.0-85017568310&partnerID=MN8TOARS.
    10.5966/sctm.2016-0033
  32. Teixeira, Graciosa Q.; Leite Pereira, Catarina; Castro, Flávia; Ferreira, Joana R.; Gomez-Lazaro, Maria; Aguiar, Paulo; Barbosa, Mário A.; Neidlinger-Wilke, Cornelia; Goncalves, Raquel M.. "Anti-inflammatory Chitosan/Poly-y-glutamic acid nanoparticles control inflammation while remodeling extracellular matrix in degenerated intervertebral disc". Acta Biomaterialia 42 (2016): 168-179. http://dx.doi.org/10.1016/j.actbio.2016.06.013.
    10.1016/j.actbio.2016.06.013
  33. Ferreira, L.B.; Tavares, C.; Pestana, A.; Pereira, C.L.; Eloy, C.; Pinto, M.T.; Castro, P.; et al. "Osteopontin-a splice variant is overexpressed in papillary thyroid carcinoma and modulates invasive behavior". Oncotarget 7 32 (2016): 52003-52016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84982293109&partnerID=MN8TOARS.
    10.18632/oncotarget.10468
  34. Pereira, C.L.; Teixeira, G.Q.; Ribeiro-Machado, C.; Caldeira, J.; Costa, M.; Figueiredo, F.; Fernandes, R.; et al. "Mesenchymal Stem/Stromal Cells seeded on cartilaginous endplates promote Intervertebral Disc Regeneration through Extracellular Matrix Remodeling". Scientific Reports 6 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84988672665&partnerID=MN8TOARS.
    10.1038/srep33836
  35. Teixeira, G.Q.; Boldt, A.; Nagl, I.; Pereira, C.L.; Benz, K.; Wilke, H.-J.; Ignatius, A.; et al. "A Degenerative/Proinflammatory Intervertebral Disc Organ Culture: An Ex Vivo Model for Anti-inflammatory Drug and Cell Therapy". Tissue Engineering - Part C: Methods 22 1 (2016): 8-19. http://www.scopus.com/inward/record.url?eid=2-s2.0-84954326138&partnerID=MN8TOARS.
    10.1089/ten.tec.2015.0195
  36. Gonçalves, R.M.; Pereira, A.C.L.; Pereira, I.O.; Oliveira, M.J.; Barbosa, M.A.. "Macrophage response to chitosan/poly-(¿-glutamic acid) nanoparticles carrying an anti-inflammatory drug". Journal of Materials Science: Materials in Medicine 26 4 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84925061574&partnerID=MN8TOARS.
    10.1007/s10856-015-5496-1
  37. Antunes, J.C.; Tsaryk, R.; Gonçalves, R.M.; Pereira, C.L.; Landes, C.; Brochhausen, C.; Ghanaati, S.; Barbosa, M.A.; Kirkpatrick, C.J.. "Poly(¿-Glutamic Acid) as an Exogenous Promoter of Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells". Tissue Engineering - Part A 21 11-12 (2015): 1869-1885. http://www.scopus.com/inward/record.url?eid=2-s2.0-84930157502&partnerID=MN8TOARS.
    10.1089/ten.tea.2014.0386
  38. Pereira, C.L.; Gonçalves, R.M.; Peroglio, M.; Pattappa, G.; D'Este, M.; Eglin, D.; Barbosa, M.A.; Alini, M.; Grad, S.. "The effect of hyaluronan-based delivery of stromal cell-derived factor-1 on the recruitment of MSCs in degenerating intervertebral discs". Biomaterials 35 28 (2014): 8144-8153. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903746142&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2014.06.017
  39. Pereira, C.L.; Antunes, J.C.; Gonçalves, R.M.; Ferreira-Da-Silva, F.; Barbosa, M.A.. "Biosynthesis of highly pure poly-¿-glutamic acid for biomedical applications". Journal of Materials Science: Materials in Medicine 23 7 (2012): 1583-1591. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863314791&partnerID=MN8TOARS.
    10.1007/s10856-012-4639-x
  40. Antunes, J.C.; Pereira, C.L.; Molinos, M.; Ferreira-Da-Silva, F.; Dessi, M.; Gloria, A.; Ambrosio, L.; Gonca¸lves, R.M.; Barbosa, M.A.. "Layer-by-layer self-assembly of chitosan and poly(¿-glutamic acid) into polyelectrolyte complexes". Biomacromolecules 12 12 (2011): 4183-4195. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856258191&partnerID=MN8TOARS.
    10.1021/bm2008235
  41. Pereira, C.L.; Gonçalves, R.M.; Ferreira-Da-silva, F.; Antunes, J.C.; Molinos, M.; Barbosa, M.A.. "Biosynthesis of poly-¿-glutamic acid and its application in the development of chitosan/poly-¿-glutamic acid nanoparticles for drug delivery". 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-84887002343&partnerID=MN8TOARS.
Capítulo de livro
  1. Leite Pereira, Catarina. "Organ-on-chip models for other mucosal permeability studies". In Concepts and Models for Drug Permeability Studies,. Elsevier, 2023.
    Aceite para publicação
  2. Pereira, Ana Catarina Leite; Grad, Sibylle; Barbosa, Mário Adolfo; Goncalves, Raquel M.. "Cell recruitment for degenerated intervertebral disc". In Gene and Cell Delivery for Intervertebral Disc Degeneration. CRC Press, 2018.
    Publicado
Livro
  1. Sarmento, Bruno; Leite Pereira, Catarina; das Neves, José. Concepts and Models for Drug Permeability Studies, 2 Edition. 2023.
    Aceite para publicação • Editor
  2. Sarmento, Bruno; Leite Pereira, Catarina; das Neves, José. Concepts and models for drug permeability studies: Cell and tissue based in vitro culture models. Portugal: Elsevier. 2023.
    No prelo
Poster em conferência
  1. Sofia Costa; Sarmento, Bruno; Leite Pereira, Catarina. "Multicellular tumor spheroids: modelling osteosarcoma as an in vitro tool to screen novel therapeutic strategies". Trabalho apresentado em Beyond REMODEL: 3R models for biomedical research, 2023.
  2. Sofia Costa; Sarmento, Bruno; Leite Pereira, Catarina. "Modeling Osteosarcoma as an in vitro 3D tool to screen novel therapies". Trabalho apresentado em 4th Young Scientist Meeting of the Spanish-Portuguese Local Chapter of CRS, 2023.
  3. Leite Pereira, Catarina. "PLGA-based nanoparticles for ibuprofen delivery - Targeting macrophages phenotype to modulate inflammation in cartilage degeneration". Trabalho apresentado em European Technology Platform Nanomedicine - ETPN 2022, 2022.
  4. NETO, ESTRELA; Monteiro, Ana Carolina; Leite Pereira, Catarina; Sarmento, Bruno; Lamghari, Meriem. "Nanodelivery systems to control inflammation in neurovascularized bone-on-a-chip model". Trabalho apresentado em European Technology Platform on Nanomedicine - ETPN 2022, 2022.
  5. Dias, Sofia; Leite Pereira, Catarina; Sarmento, Bruno. "3D Colorectal cancer spheroid model combined with a colon model for drug and nanoparticle safety and efficacy screening". Trabalho apresentado em 5th PhDay - Building Paths: The Science Behind Us, 2022.
  6. Castro, Flávia; Leite Pereira, Catarina; Gonçalves, Raquel; Oliveira, Maria José. "Chitosan/gamma-PGA nanoparticles-based immunotherapy as adjuvant to radiotherapy in breast cancer". Trabalho apresentado em Web Conference “Cancer Biology: from basic to Translational Research”, Portuguese Cancer Ligue, 2020.
  7. Castro, Flávia; Marta Laranjeiro Pinto; Leite Pereira, Catarina; Serre, Karine; Fátima Gartner; Mário Adolfo Barbosa ; Olivier de Wever; Raquel Madeira Gonçalves; Maria José Oliveira. "Reprogramming the breast tumor microenvironment: chitosan and poly(y-glutamic acid) nanoparticles in sight". Trabalho apresentado em 26th Porto Cancer Meeting: The Cancer Ecosystem: From Research to Pathology and Treatment, 2019.
  8. Castro, Flávia; Marta Laranjeiro Pinto; Leite Pereira, Catarina; Serre, Karine; Fátima Gartner; Mário Adolfo Barbosa ; Olivier de Wever; Raquel Madeira Gonçalves; Maria José Oliveira. "Chitosan/poly(y-glutamic acid) nanoparticles and radiotherapy: a winning combination to fight cancer". Trabalho apresentado em ASPIC International Meeting ¿ Current Trends in Immunotherapy Research and Treatment, Salamanca, Spain, 2019.
  9. Leite Pereira, Catarina. "Contribution of Chitosan (Ch) and poly(gamma)-glutamic (PGA) to the immunomodulatory role of Ch/PGA-based nanoparticles.". Trabalho apresentado em European Society for Biomaterials Conference, 2018.
  10. Pereira, Ana Catarina Leite. "SDF-1 mediated-mesenchymal stem cells recruitment: a new perspective for intervertebral disc degeneration treatment". Trabalho apresentado em eCM XVIII: Cartilage & Disc: Repair and Regeneration, 2018.
  11. Leite Pereira, Catarina. "Rat Intervertebral Disc Degeneration and Herniation Model for Local Biomaterial Delivery". Trabalho apresentado em European Society for Biomaterials Conference, 2017.
  12. Leite Pereira, Catarina. "Intervertebral Disc degeneration: cells navigation towards regeneration?". Trabalho apresentado em China-Europe Society for Biomaterials Conference, 2017.
  13. Castro, Flávia; Marta Laranjeiro Pinto; Leite Pereira, Catarina; Mário Adolfo Barbosa ; Raquel Madeira Gonçalves; Maria José Oliveira. "Reeducating antigen-presenting cells: an interferon-gamma delivery system for anticancer therapy". Trabalho apresentado em XI National Congress of the Italian Society of Immunology, clinical Immunology and allergology, Bari, Italy, 2017.
  14. Leite Pereira, Catarina. "Bioimaging Tools Towards the Quantification of Extracellular Matrix Production in Degenerating Intervertebral Discs". Trabalho apresentado em 4th International Symposium in Applied Bioimaging, 2015.
  15. Leite Pereira, Catarina. "Intradiscal application of anti-inflammatory nanoparticles control inflammation while remodel extracellular matrix of degenerated intervertebral disc". Trabalho apresentado em Advanced Summer School: Interrogations at the Biointerface - the Nano/Medicine Interface, 2015.
  16. Leite Pereira, Catarina. "Mesenchymal Stem migration in the intervertebral disc: a new route for regeneration through the activation of endogenous cells and increased matrix production.". Trabalho apresentado em 5th Advanced Summer School Interrogations at the Biointerface, 2015.
  17. Leite Pereira, Catarina. "Comparison of an anti-inflammatory drug delivery system versus MSC therapy to control inflammation in a pro-inflammatory intervertebral disc organ culture system". Trabalho apresentado em International Society for the Study of the Lumbar Spine (ISSLS) Annual Meeting, 2015.
  18. Leite Pereira, Catarina. "Stromal Cell Derived Factor-1-delivery system: a new approach for the recruitment of Mesenchymal Stem Cells in degenerating intervertebral disc". Trabalho apresentado em World Forum for Spine Research, 2014.
  19. Leite Pereira, Catarina. "Mesenchymal Stem Cells Recruitment by SDF-1 delivery in a degenerating Intervertebral Disc". Trabalho apresentado em 1st Symposium in Applied Bioimaging, 2013.
  20. Leite Pereira, Catarina. "Development of a chemoattractant delivery system for MSCs recruitment in the degenerated IVD". Trabalho apresentado em European Orthopaedic Research Society (EORS) Conference, 2012.
  21. Leite Pereira, Catarina. "Chitosan/Poly¿Glutamic Acid Nanoparticles as an anti-inflammatory drug delivery system for intervertebral disc". Trabalho apresentado em 9th World Biomaterials Conference, 2012.
  22. Leite Pereira, Catarina. "Layer-by-layer self-assembly of Chitosan and Poly(¿-glutamic acid) into polyelectrolyte complexes". Trabalho apresentado em 9th World Biomaterials Conference, 2012.
    10.1021/bm2008235
Resumo em conferência
  1. Castro, Flávia; Marta Laranjeiro Pinto; Andreia Machado Silva; Leite Pereira, Catarina; Santos, Susana G.; Barbosa, Mário Adolfo; Olivier de Wever. Autor correspondente: Castro, Flávia. "Harnessing chitosan/Poly(y)-glutamic acid nanoparticles for immunomodulation at the tumour microenvironment". Trabalho apresentado em 5th Biennial Congress of the European Association for Cancer Research (EACR25), Amesterdam, 2018.
    Publicado
  2. Castro, Flávia; Marta Laranjeiro Pinto; Andreia Machado Silva; Leite Pereira, Catarina; Olivier de Wever; Karine Serre; Raquel Madeira Gonçalves; Maria José Oliveira. "Reprogramming antigen-presenting cells: a chitosan/y-PGA nanoparticles for anticancer therapy". Trabalho apresentado em 8th International conference on Tumor Microenvironment: Progression, Therapy & Prevention, Lisbon, 2018.
    Publicado
Tese / Dissertação
  1. Pereira, Ana Catarina Leite. "MESENCHYMAL STEM/STROMAL CELLS RECRUITMENT FOR INTERVERTEBRAL DISC REGENERATION". Doutoramento, Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, 2017.
  2. Pereira, Ana Catarina Leite. "Biosynthesis of Poly-Gamma-Glutamic Acid and Its application in Chitosan/Poly-gamma-glutamic Acid Nanoparticles". Mestrado, Universidade do Porto Faculdade de Engenharia, 2010.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/02/15 Osteosarcoma Multicellular Spheroids Meet Microfluidics: A Tool to Screen New Therapeutical Strategies XVth Spanish-Portuguese Conference on Controlled Drug Delivery Conference
SPLC-CRS (Lisbon, Portugal)
2023/05/08 Invited Speaker at the Third Meeting of the PhD in Biomedical Sciences (ICBAS/UP): “From Biology, through Bioengineering, towards Biomedical applications” Third Meeting of the PhD in Biomedical Sciences
Instituto de Ciências Biomédicas Abel Salazar, University of Porto (Porto, Portugal)
2023/04/19 Invited Speaker at VIII Conferences in Oncology Research: "Bio-inspired and Bioengineered Technology for OSteosarcoma – unraveling OS to advance in novel targeted therapies" VIII Conferences in Oncology Research
Portuguese League Against Cancer (Lisbon, Portugal)
2022/03/31 Invited Speaker at the VII Bioengineering Week IST - Nanomedicine in treatment and diagnosis of diseases: "Nanomedicines for regenerative medicine" VII Bioengineering Week of IST
Instituto Superior Técnico, University of Lisbon (Lisbon, Portugal)
2021/07/26 PLGA-based nanoparticles for ibuprofen delivery - Targeting macrophages phenotype to modulate inflammation in cartilage degeneration Controlled Release Society (CRS) 2021 Virtual Annual Meeting
Controlled Release Society
2018/02/23 Invited Speaker at III Bioengineering Conferences from UTAD: "Bioengineering strategies for intervertebral disc degeneration and low back pain treatment" III Bioengineering Conferences from UTAD
University of Trans-os-Montes e Alto Douro (Vila Real, Portugal)
2017/10/06 Mesenchymal stem/stromal cells present an immunomodulatory role through paracrine mechanism in degenerated but not in healthy IVD Eurospine Congress
(Berlin, Alemanha)
2017/09/07 Hyaluronan-based hydrogel for SDF-1 delivery in the intervertebral disc: insights from an ex vivo model European Society for Biomaterials Conference
IEEE (Atenas, Grécia)
2017/09/06 Chitosan/Poly-gamma-glutamic acid nanoperticles as the backbone of immunomodulatory therapies European Society for Biomaterials Conference
(Atenas, Grécia)
2017 Mesenchymal Stem/Stromal Cells Recruitment from the Cartilaginous Endplate: a new perspective for IVD regenerative strategies through ECM remodeling Tissue Engineering and Regenerative Medicine International Society Conference
AO Research Institute (Davos, Suiça)
2016/10/06 Extracellular Matrix Remodeling in intervertebral Disc by Mesenchymal Stem/Stromal Cells Recruitment from the Cartilaginous Endplate: a new perspective for IVD regenerative strategies Eurospine Congress
(Berlin, Alemanha)
2016/07/30 Local treatment of inflammation in degenerated intervertebral disc using poly(gamma-glutamic acid)-based nanocomplexes promotes extracellular matrix remodeling Tissue Engineering and Regenerative Medicine International Society Conference
(Uppsala, Suécia)
2016/06/30 Intervertebral Disc Regeneration: role of migrating MSCs in the Extracellular Matrix Remodeling Tissue Engineering and Regenerative Medicine International Society Conference
(Uppsala, Suécia)
2016/04/14 A nanotechnology-based therapy to target inflammation in degenerated intervertebral disc: first results from an ex vivo disc organ culture Global Spine Congress/World Forum for Spine Research
(Dubai, Emiratos Árabes Unidos)
2016/03/04 Células estaminais/estromais mesenquimatosas através da endplate cartilaginea: uma nova rota no tratamento da degeneração do disco intervertebral 6º Congresso Nacional da Sociedade Portuguesa de Patologia da Coluna Vertebral
(Vila Nova de Gaia, Portugal)
2015/10/13 Poly(gamma-glutamic acid) and poly(gamma-glutamic acid)-based nanocomplexes enhance type II collagen production in intervertebral disc BIOMAT 2015
WORLD SCIENTIFIC (Ile de Ré, França)
2015/04/09 Intervertebral disc regeneration: the role of MSCs recruitment by hyaluronan-based delivery of SDF-1 in matrix production improvement. BioSpine Congress
IEEE (Berlin, Alemanha)
2015/04/09 Local treatment of inflammation and degeneration of intervertebral disc: ex vivo study of anti-inflammatory drug delivery system based on Chitosan/Poly-(gamma-Glutamic acid) nanoparticles BioSpine Congress
(Berlin, Alemanha)
2014/09/09 Development of a Chemoattractant Delivery System for Mesenchymal Stem Cells Recruitment to Intervertebral Disc 25th European Conference on Biomaterials
(Madrid, Espanha)
2014/09/01 Treatment of a degenerative/pro-inflammatory intervertebral disc organ culture with Chitosan/Poly-¿-glutamic acid nanoparticles carrying and anti-inflammatory drug 26th European Conference on Biomaterials
(Liverpool, Reino Unido)
2011/09/05 Biosynthesis of ¿-Polyglutamic Acid and its application in the development of Chitosan/¿-Polyglutamic Acid Nanoparticles for Drug Delivery 24th European Conference on Biomaterials
(Dublin, Irlanda)
2011/07/08 Development of Chitosan-based Delivery System to recruit Mesenchymal Stem Cells Tissue Engineering and Regenerative Medicine International Society Conference
IEEE (Granada, Espanha)
2011/04/05 Delivery system based on Chitosan/¿-Polyglutamic Polyelectrolyte Complexes recruits Mesenchymal Stem cells. 3rd Chinese-European Symposium on Biomaterials in Regenerative Medicine
(Nanjing, China)
2011/03/23 Chemoattraction of Mesenchymal Stem Cells to intervertebral disc: design and characterization of a chemokine delivery system Global Spine Congress
(Barcelona, Espanha)
2010/09/12 Development of Chitosan/Poly-¿-glutamic Acid Polyelectrolyte Complexes for Intervertebral Disc Degeneration 23rd European Conference on Biomaterials
(Tampere, Finlândia)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2024/09/16 - Atual Ana Cristina Duarte, MSc Candidate - Lung-on-chip platform development to study osteosarcoma metastasis and screening of nanotherapeutics
Orientador
Master (Mestrado)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade de Coimbra, Portugal
2024/09/16 - Atual Maria Francisca Côrte-Real, MSc - Addressing Crohn's disease using bioengineering tools: Comprehensive characterization and validation of an immunocompetent 3D intestinal model as a screening platform for mRNA/siRNA-based therapies
Orientador
Master (Mestrado)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2021/09 - 2025/09 Sofia Dias, PhD Candidate - 3D-CRCol: 3D organotypic ColoRectal Cancer spheroid model with healthy cOLon for drug and nanoparticle safety and efficacy screening
Coorientador de Sofia Dias
Biomedical Sciences (Doutoramento)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/11/01 - 2024/10/31 Diogo Horta, PhD Candidate: A swiss-knife nanotechnology approach to glioblastoma treatment
Coorientador de Diogo de Freitas Horta
Neurosciences (Doutoramento)
Universidade do Porto, Portugal

Universidade do Porto Faculdade de Medicina, Portugal
2024/03/05 - 2024/10/21 ERASMUS+ Student - Ilaria Gasperini, MSc - Approaching Crohn's Disease Treatments based on nanomedicines
Orientador
Medical Biotechnology (Mestrado)
Università degli Studi di Bologna, Itália
2024/02/01 - 2024/06/30 Carolina Vieira, BSc Internship - Development of nanoformulations for Osteossarcoma tumor microenvironment immunomodulation
Orientador
Bioengineering (Iniciação científica)
Universidade do Porto Faculdade de Engenharia, Portugal
2021/06/01 - 2023/01/31 Cristina Santarcangelo, Visiting PhD Candidate: in vitro model system of the intestine to study nutraceuticals properties
Coorientador
University of Napoli Federico II, Itália
2022/07/01 - 2023 Sofia Costa, MSc Candidate: Osteosarcoma (OS) Multicellular Tumor spheroids: modeling OS to address the potential of a nanotechnology-based immunomodulatory strategy in OS treatment
Orientador
Mestrado em Aplicações em Biotecnologia e Biologia Sintética (Mestrado)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
2020/12/01 - 2021/07/31 João Rodrigues, MSc Candidate: Tumor-on-chip for Osteosarcoma (OS) drug screening: development of OS tumor microenvironment (TME)-compartment
Orientador de João Rodrigues
Bioengineering (Mestrado)
Universidade do Porto, Portugal
2021/01/02 - 2021/07/15 Beatriz Ribeiro, Trainee (BSc candidate) - Incorporation of anti-inflammatory nanoparticles in 3D scaffolds for articular cartilage regeneration
Coorientador de Beatriz Ribeiro
BSc (Iniciação científica)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2017/09/18 - 2018/07/11 Rui Almeida (MSc Candidate): Immunomodulatory Nanoparticles for Intervertebral Disc Degeneration
Orientador de Rui Almeida
Mestrado Integrado em Bioengenharia (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2018/04/02 - 2018/06/30 Leonor Correia, Trainee (BSc candidate): Imaging data Analysis of Intervertebral disc from human and bovine tissues
Orientador de Maria Leonor Correia
Mestrado Integrado em Bioengenharia (Licenciatura/Bacharelato)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2018/04/02 - 2018/06/30 Renata Basto, Trainee (BSc candidate): Histological processing and analysis of Intervertebral disc from human and bovine tissues
Orientador de Renata Basto
Mestrado Integrado em Bioenhenharia (Licenciatura/Bacharelato)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2017/02/16 - 2017/07/31 Rui Almeida, Trainee (BSc candidate): Design of nanocapsules based on chitosan/poly-gamma-glutamic acid electrostatic interaction for drug delivery
Coorientador de Rui Almeida
Mestrado Integrado em Bioengenharia (Licenciatura/Bacharelato)
Universidade do Porto Faculdade de Engenharia, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2013 - Atual Porto de Crianças - “Era uma vez…o osso e o sistema Imune: O exército que olha por nós” - with the aim to support the primary schools in their educational program, namely in the bone area. (2013)
Outro (Coorganizador)
Instituto Nacional de Engenharia Biomédica, Portugal
2011 - Atual “O INEB vai à Escola” created with the aim of increasing the awareness of high school students to the field of biomedical engineering and science in general (2011)
Conferência (Coorganizador)
Instituto Nacional de Engenharia Biomédica, Portugal
2022/10/01 - 2023/02/07 Organization of the 4th Spanish-Portuguese Local Chapter of the Controlled Release Society Young Scientist Meeting 2023 (2023/02/06 - 2023/02/07)
Conferência (Presidente da Comissão Organizadora)
Spanish-Portuguese Local Chapter of the Controlled Release Society, Espanha
2014/06/16 - 2014/06/26 INEB 25 ANOS: "A Engenharia Biomédica num Quarteirão de Histórias" A exposição consistiu numa forma divertida de explicar alguns dos principais projetos desenvolvidos no INEB nestes últimos 25 anos, associando-os a uma sardinha. (2014/06/16)
Exposição (Coorganizador)
Instituto Nacional de Engenharia Biomédica, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2011/03/17 - Atual MOSTRA DA UP: The Exhibition of the University of Porto is an annual event that aims to guide and raise awarness of Basic and Secondary Education students and the population in general, about the training offer and work carried out by the organic units belonging to the University of Porto.
Exposição
Universidade do Porto, Portugal
2020/10/14 - 2020/10/15 15th Annual ETPN – European Technology Platform on Nanomedicine event
Congresso
15th Annual Event
European Technology Platform on Nanomedicine, França

Arbitragem científica em conferência

Nome da conferência Local da conferência
2021/12/01 - 2023/06/07 4th SPLC-CRS Young Scientists Meeting - Bridging Science, Delivering Oportunities SPLC-CRS Young Scientist Board
2022/10/01 - 2022/10/04 5th PhDay: “Building Paths: The Science Behind Us” i3S
2022/02/28 - 2022/03 Controlled Release Society (CRS) Annual Meeting and Expo 2022 CRS
2021/04 - 2021/09 31st Conference of the European Society for Biomaterials 2021 ESB/INEB
2021/02 - 2021/03 Controlled Release Society (CRS) Virtual Annual Meeting 2021 CRS
2018/05/01 - 2018/05/30 1st PhDay at i3S - From bench to stage, from desk to forum i3S

Comissão de avaliação

Descrição da atividade
Tipo de assessoria
Instituição / Organização Entidade financiadora
2023/02/01 - Atual Invited External Reviewer for the Research Prize of The Lister Institute of Preventive Medicine
Avaliador
The Lister Institute of Preventive Medicine, Reino Unido The Lister Institute of Preventive Medicine
2023 - Atual Graduate Women in Science (GWIS) National Fellowship Program application 2023 Evaluation
Avaliador
Graduate Women in Science (GWIS) , Estados Unidos
2021 - Atual Invited external grant reviewer for the National Science Centre (NCN) Poland
Avaliador
Narodowe Centrum Nauki

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2022 - Atual "Nanomedicines for regenerative medicine" - Curricular Unit in Nanotechnology in Health of the Biongineering BSc course of ICBAS/UP Bioengineering (Bacharelato) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/09/17 - Atual "Nanomedicine in Regenerative Medicine" in Advanced Course in Nanotechnology, Drug Delivery and Drug Targeting, CESPU Doctoral Program of Biological Sciences Applied to Health (Doutoramento) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2023/03/22 - 2023/03/22 COST ACTION GEMSTONE Trainning Schoool- "In vitro 3D modeling of osteosarcoma at the cellular and ECM level: technical highlights and challenges In vitro 3D modeling (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2022/07/26 €5.4 million project aims to create oral therapy for Crohn's Disease - "researchers will receive 400,000 euros to develop a three-dimensional (3D) model that simulates the "inflamed intestine" of this disease and can be used "to test the effectiveness of nanomedicines" . Expresso
2021/12/22 Interview about the pize of Liga Portuguesa Contra o Cancro (15K euros award) - General Public Dissemination Noticias UP
2019/11/18 i3S: o dia a dia do instituto que vira o cancro do avesso (Cancer dedicated day of i3S) - General Public Dissemination Noticias Magazzine

Entrevista / Programa (rádio / tv)

Programa Tema
2022/07/27 - Atual National News - GENEGUT Press release: dissemination of project goal and focus of i3S team, to the general public European Project Genegut
2021/10 - 2021/10 Porto Canal (National TV Channel) - Somos Academia - Role of science in Postgraduate Studies Research-academia interaction in our research group at Instituto de Investigação e Inovação em Saúde. Scientific training, transversal skills, communication tools and innovation, the key players.

Membro de associação

Nome da associação Tipo de participação
2023/04/01 - Atual ASPIC - Associção Portuguesa de Investigação em Cancro (ASPIC627)
2023/04/01 - Atual EACR - European Association for Cancer Research
2022/01/01 - Atual SPLC-CRS: Spanish-Portuguese Local Chapter of Controled Release Society Young Scientist Board Member
2020 - Atual CRS - Controlled Release Society
2011 - Atual ESB - European Society for Biomaterials
2015 - 2016 AO SPINE

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2022/07 - Atual PhD Advisory Committee member - PhD Candidate Inês Saraiva (FCT Maria de Sousa Fellows, IMM, Faculty of Medicine of University of Lisbon)
Consultor
Universidade de Lisboa Faculdade de Medicina, Portugal
2021/07 - Atual PhD Advisory Committee member - PhD Candidate Emine Kahraman (Doctoral Program in Biomedical Engineering, FEUP)
Consultor
Universidade do Porto Faculdade de Engenharia, Portugal

Revisão ad hoc de artigos em revista

Nome da revista (ISSN) Editora
2023 - Atual SLAS Technology
2021 - Atual Particle and Particle Systems Characterization (1521-4117) Wiley
2021 - Atual Drug Delivery and Translational Research (2190-3948) Springer
2021 - Atual ACS applied materials & interfaces
2020 - Atual Drug Discovery Today (1359-6446) Elsevier
2020 - Atual Acta Biomaterialia (1742-7061) Elsevier
2020 - Atual Biomaterials Science (2047-4830) The Royal Society of Chemistry
2019 - Atual Biomaterials (0142-9612) Elsevier
2018 - Atual European Cells and Materials (1473-2262)
2023/03/01 - 2023/03/26 Wiley-VCH book proposal Wiley-VCH book proposal
Distinções

Prémio

2023 Innovate Competition da iMed Conference® 15.0
AstraZeneca AB, Suécia

Faculdade de Ciências Médicas da Universidade Nova de Lisboa, Portugal
2022 Award Nonô Sarcoma Pediatrico
Liga Portuguesa Contra o Cancro, Portugal
2018 Julia Polak European Doctoral Award
European Society for Biomaterials, França
2016 3rd Place, Best Research Article Award
2015 Best Poster Presentation Award at Advanced Summer School: THE NANO / MEDICINE INTERFACE
2015 AO Spine European Young Researcher Award
AOSpine International, Suiça
2013 Best Poster Presentation Award at the International Symposium in Applied Bioimaging
Instituto Nacional de Engenharia Biomédica, Portugal