| Artigo em revista |
- Almeida, Maria. "Cxcl12 deletion in mesenchymal cells increases bone turnover and attenuates the loss of cortical bone caused
by estrogen deficiency in mice.". Journal of bone and mineral research : the official journal of the American Society for
Bone and Mineral Research (2020): https://doi.org/10.1002/jbmr.4002.
10.1002/jbmr.4002
- Almeida, Maria. "Stimulation of Piezo1 by mechanical signals promotes bone anabolism.". eLife (2019): https://europepmc.org/articles/PMC6779475.
10.7554/eLife.49631
- Almeida, Maria. "Elimination of senescent osteoclast progenitors has no effect on the age-associated loss of bone mass in
mice.". Aging cell (2019): https://europepmc.org/articles/PMC6516158.
10.1111/acel.12923
- Almeida, Maria. "Sirtuins and FoxOs in osteoporosis and osteoarthritis.". Bone (2019): https://doi.org/10.1016/j.bone.2019.01.018.
10.1016/j.bone.2019.01.018
- Almeida, Maria. "The Spectrum of Fundamental Basic Science Discoveries Contributing to Organismal Aging.". Journal of bone
and mineral research : the official journal of the American Society for Bone and Mineral Research (2018): https://europepmc.org/articles/PMC6327947.
10.1002/jbmr.3564
- Almeida, Maria. "The YAP/TAZ transcriptional co-activators have opposing effects at different stages of osteoblast differentiation.".
Bone (2018): https://europepmc.org/articles/PMC5970058.
10.1016/j.bone.2018.04.001
- Almeida, Maria. "The Role of FoxOs in Bone Health and Disease.". Current topics in developmental biology (2017): https://doi.org/10.1016/bs.ctdb.2017.10.004.
10.1016/bs.ctdb.2017.10.004
- Marilina Piemontese; Maria Almeida; Alexander G. Robling; Ha-Neui Kim; Jinhu Xiong; Jeff D. Thostenson; Robert S. Weinstein;
et al. "Old age causes de novo intracortical bone remodeling and porosity in mice". JCI Insight 2 17 (2017): https://doi.org/10.1172%2Fjci.insight.93771.
10.1172/jci.insight.93771
- Almeida, Maria. "DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age.". Aging
cell (2017): https://europepmc.org/articles/PMC5506444.
10.1111/acel.12597
- Almeida, Maria. "Estrogens and Androgens in Skeletal Physiology and Pathophysiology.". Physiological reviews (2017):
https://europepmc.org/articles/PMC5539371.
10.1152/physrev.00033.2015
- Almeida, Maria. "The Effects of Aging and Sex Steroid Deficiency on the Murine Skeleton Are Independent and Mechanistically
Distinct.". Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
(2016): https://europepmc.org/articles/PMC5340621.
10.1002/jbmr.3014
- Almeida, Maria. "CathepsinKCre mediated deletion of ßcatenin results in dramatic loss of bone mass by targeting both osteoclasts
and osteoblastic cells.". Scientific reports (2016): https://europepmc.org/articles/PMC5090355.
10.1038/srep36201
- Almeida, Maria. "Deletion of FoxO1, 3, and 4 in Osteoblast Progenitors Attenuates the Loss of Cancellous Bone Mass in a Mouse
Model of Type 1 Diabetes.". Journal of bone and mineral research : the official journal of the American Society for Bone
and Mineral Research (2016): https://europepmc.org/articles/PMC5492385.
10.1002/jbmr.2934
- Almeida, Maria. "Low bone mass and changes in the osteocyte network in mice lacking autophagy in the osteoblast lineage.".
Scientific reports (2016): https://europepmc.org/articles/PMC4827128.
10.1038/srep24262
- Almeida, Maria. "Skeletal inflammation and attenuation of Wnt signaling, Wnt ligand expression, and bone formation in atherosclerotic
ApoE-null mice.". American journal of physiology. Endocrinology and metabolism (2016): https://europepmc.org/articles/PMC6415649.
10.1152/ajpendo.00501.2015
- Almeida, Maria. "Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs.". Molecular endocrinology (Baltimore, Md.)
(2015): https://europepmc.org/articles/PMC4588729.
10.1210/me.2015-1133
- Almeida, Maria. "The Effects of Androgens on Murine Cortical Bone Do Not Require AR or ERa Signaling in Osteoblasts and Osteoclasts.".
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research (2015):
https://europepmc.org/articles/PMC4871247.
10.1002/jbmr.2485
- Almeida, Maria. "Suppression of autophagy in osteocytes does not modify the adverse effects of glucocorticoids on cortical
bone.". Bone (2015): https://europepmc.org/articles/PMC4387016.
10.1016/j.bone.2015.02.005
- Almeida, Maria. "Sirtuin1 (Sirt1) promotes cortical bone formation by preventing ß-catenin sequestration by FoxO transcription
factors in osteoblast progenitors.". The Journal of biological chemistry (2014): https://europepmc.org/articles/PMC4148840.
10.1074/jbc.M114.561803
- Almeida, Maria. "SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass.". Aging cell
(2014): https://europepmc.org/articles/PMC4172519.
10.1111/acel.12220
- Almeida, Maria. "FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation.". Nature
communications (2014): https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24781012/?tool=EBI.
10.1038/ncomms4773
- Almeida, Maria. "The role of estrogen and androgen receptors in bone health and disease.". Nature reviews. Endocrinology
(2013): https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24042328/?tool=EBI.
10.1038/nrendo.2013.179
- Almeida, Maria. "FOXOs attenuate bone formation by suppressing Wnt signaling.". The Journal of clinical investigation
(2013): https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23867625/?tool=EBI.
10.1172/JCI68049
- Almeida, Maria. "Basic biology of skeletal aging: role of stress response pathways.". The journals of gerontology. Series
A, Biological sciences and medical sciences (2013): https://europepmc.org/articles/PMC3779633.
10.1093/gerona/glt079
- Almeida, Maria. "Suppression of autophagy in osteocytes mimics skeletal aging.". The Journal of biological chemistry
(2013): https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23645674/?tool=EBI.
10.1074/jbc.M112.444190
- Almeida, Maria. "Non-nuclear-initiated actions of the estrogen receptor protect cortical bone mass.". Molecular endocrinology
(Baltimore, Md.) (2013): https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23443267/?tool=EBI.
10.1210/me.2012-1368
- Almeida, Maria. "Estrogen receptor-a signaling in osteoblast progenitors stimulates cortical bone accrual.". The Journal
of clinical investigation (2012): https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23221342/?tool=EBI.
10.1172/JCI65910
- Almeida, Maria. "Receptor activator of nuclear factor ¿B ligand (RANKL) protein expression by B lymphocytes contributes to
ovariectomy-induced bone loss.". The Journal of biological chemistry (2012): https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22782898/?tool=EBI.
10.1074/jbc.M112.377945
- Almeida, Maria. "Aging mechanisms in bone.". BoneKEy reports (2012): https://europepmc.org/articles/PMC3659822.
10.1038/bonekey.2012.102
- Almeida, Maria. "Glucocorticoids and tumor necrosis factor a increase oxidative stress and suppress Wnt protein signaling
in osteoblasts.". The Journal of biological chemistry (2011): https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22030390/?tool=EBI.
10.1074/jbc.M111.283481
- Almeida, Maria. "Osteoprotegerin prevents glucocorticoid-induced osteocyte apoptosis in mice.". Endocrinology (2011):
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21771887/?tool=EBI.
10.1210/en.2011-0170
- Almeida, Maria. "Unraveling the role of FoxOs in bone--insights from mouse models.". Bone (2011): https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21664311/?tool=EBI.
10.1016/j.bone.2011.05.023
- Almeida, Maria. "Decreased oxidative stress and greater bone anabolism in the aged, when compared to the young, murine skeleton
with parathyroid hormone administration.". Aging cell (2010): https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20698835/?tool=EBI.
10.1111/j.1474-9726.2010.00616.x
- Almeida, Maria. "Oxidative stress stimulates apoptosis and activates NF-kappaB in osteoblastic cells via a PKCbeta/p66shc
signaling cascade: counter regulation by estrogens or androgens.". Molecular endocrinology (Baltimore, Md.) (2010):
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20685851/?tool=EBI.
10.1210/me.2010-0189
- Almeida, Maria. "Intermittent parathyroid hormone administration counteracts the adverse effects of glucocorticoids on osteoblast
and osteocyte viability, bone formation, and strength in mice.". Endocrinology (2010): https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20410195/?tool=EBI.
10.1210/en.2009-1488
- Almeida, Maria. "Estrogens attenuate oxidative stress and the differentiation and apoptosis of osteoblasts by DNA-binding-independent
actions of the ERalpha.". Journal of bone and mineral research : the official journal of the American Society for Bone
and Mineral Research (2010): https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19821774/?tool=EBI.
10.1359/jbmr.091017
- Almeida, Maria. "FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in
mice.". Cell metabolism (2010): https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20142101/?tool=EBI.
10.1016/j.cmet.2009.12.009
- Almeida, Maria. "The estrogen receptor-alpha in osteoclasts mediates the protective effects of estrogens on cancellous but
not cortical bone.". Molecular endocrinology (Baltimore, Md.) (2010): https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20053716/?tool=EBI.
10.1210/me.2009-0354
- Almeida, Maria. "Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice.".
Aging cell (2009): https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20047574/?tool=EBI.
10.1111/j.1474-9726.2009.00545.x
- Almeida, Maria. "Increased lipid oxidation causes oxidative stress, increased peroxisome proliferator-activated receptor-gamma
expression, and diminished pro-osteogenic Wnt signaling in the skeleton.". The Journal of biological chemistry (2009):
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19657144/?tool=EBI.
10.1074/jbc.M109.023572
- Almeida, Maria. "Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids.". The
Journal of biological chemistry (2007): https://europepmc.org/articles/PMC3119455.
10.1074/jbc.M702810200
- Almeida, Maria. "Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell
factor- to forkhead box O-mediated transcription.". The Journal of biological chemistry (2007): https://doi.org/10.1074/jbc.M702811200.
10.1074/jbc.m702811200
- Almeida, Maria. "Gone with the Wnts: beta-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases
of bone, lipid, and glucose metabolism.". Molecular endocrinology (Baltimore, Md.) (2007): https://doi.org/10.1210/me.2007-0259.
10.1210/me.2007-0259
- Almeida, Maria. "Induction of osteoblast differentiation by selective activation of kinase-mediated actions of the estrogen
receptor.". Molecular and cellular biology (2006): https://europepmc.org/articles/PMC1800724.
10.1128/MCB.01550-06
- Almeida, Maria. "Classical genotropic versus kinase-initiated regulation of gene transcription by the estrogen receptor alpha.".
Endocrinology (2005): https://doi.org/10.1210/en.2005-1314.
10.1210/en.2005-1314
- Almeida, Maria. "Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts
by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT.". The
Journal of biological chemistry (2005): https://doi.org/10.1074/jbc.M502168200.
10.1074/jbc.m502168200
- Almeida, Maria. "Nongenotropic, anti-apoptotic signaling of 1alpha,25(OH)2-vitamin D3 and analogs through the ligand binding
domain of the vitamin D receptor in osteoblasts and osteocytes. Mediation by Src, phosphatidylinositol 3-, and JNK kinases.".
The Journal of biological chemistry (2005): https://doi.org/10.1074/jbc.M410720200.
10.1074/jbc.m410720200
- Almeida, Maria. "Kinase-mediated transcription, activators of nongenotropic estrogen-like signaling (ANGELS), and osteoporosis:
a different perspective on the HRT dilemma.". Kidney international. Supplement (2004): https://doi.org/10.1111/j.1523-1755.2004.09107.x.
10.1111/j.1523-1755.2004.09107.x
- Almeida, Maria. "Regulatory role of endothelium in the expression of genes affecting arterial calcification.". Biochemical
and biophysical research communications (2004): https://doi.org/10.1016/j.bbrc.2004.05.181.
10.1016/j.bbrc.2004.05.181
- Almeida, Maria. "Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex
steroids.". The Journal of clinical investigation (2003): https://europepmc.org/articles/PMC156107.
10.1172/JCI200317261
- Almeida, Maria. "The water-soluble matrix fraction from the nacre of Pinctada maxima produces earlier mineralization of MC3T3-E1
mouse pre-osteoblasts.". Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology (2003):
- Almeida, Maria. "Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima.". European journal
of biochemistry (2002): https://doi.org/10.1046/j.1432-1033.2002.03203.x.
10.1046/j.1432-1033.2002.03203.x
- Almeida, Maria. "Bioactivity of nacre water-soluble organic matrix from the bivalve mollusk Pinctada maxima in three mammalian
cell types: fibroblasts, bone marrow stromal cells and osteoblasts.". Comparative biochemistry and physiology. Part B,
Biochemistry & molecular biology (2002): https://doi.org/10.1016/s1096-4959(01)00524-3.
10.1016/s1096-4959(01)00524-3
- Almeida, Maria. "Comparative effects of nacre water-soluble matrix and dexamethasone on the alkaline phosphatase activity
of MRC-5 fibroblasts.". Journal of biomedical materials research (2001): https://doi.org/10.1002/1097-4636(200111)57:2<306::aid-jbm1172>3.0.co;2-h.
10.1002/1097-4636(200111)57:2<306::aid-jbm1172>3.0.co;2-h
- Almeida, Maria. "Characterization and quantification of chitosan extracted from nacre of the abalone Haliotis tuberculata
and the oyster Pinctada maxima.". Marine biotechnology (New York, N.Y.) (2001): https://doi.org/10.1007/s101260000042.
10.1007/s101260000042
- Almeida, Maria. "Effect of water-soluble matrix fraction extracted from the nacre of Pinctada maxima on the alkaline phosphatase
activity of cultured fibroblasts.". The Journal of experimental zoology (2000): https://doi.org/10.1002/1097-010X(20001215)288:4<327::AID-JEZ5>3.0.CO;2-#.
10.1002/1097-010x(20001215)288:4<327::aid-jez5>3.3.co;2-r
- Almeida, Maria. "Stimulation of bone marrow cells and bone formation by nacre: in vivo and in vitro studies.". Bone
(1999): https://doi.org/10.1016/s8756-3282(99)00141-6.
10.1016/s8756-3282(99)00141-6
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