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María de la Luz Cádiz Gurrea. Publicou 24 artigos em revistas especializadas. Possui 3 capítulo(s) de livros.
Identificação

Identificação pessoal

Nome completo
María de la Luz Cádiz Gurrea

Nomes de citação

  • Cádiz-Gurrea, María de la Luz

Identificadores de autor

Ciência ID
BC1F-EAC8-C092
ORCID iD
0000-0002-2613-4889
Google Scholar ID
https://scholar.google.com/citations?user=FkI16MEAAAAJ&hl=es
Researcher Id
K-9398-2014
Scopus Author Id
55454378200

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Espanhol; Castelhano (Idioma materno)
Inglês Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2)
Português Utilizador elementar (A2) Utilizador independente (B1) Utilizador elementar (A2) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2013/10/01 - 2018/03/23
Concluído
 2018 (Doktor (PhD))
Especialização em Chemistry
Universidad de Granada, Espanha
"Caracterización, purificación y evaluación de la bioactividad de fitoquímicos obtenidos de fuentes naturales" (TESE/DISSERTAÇÃO)
 Cum laude
2011/12/11
Concluído
 Máster Oficial en Biotecnología (Postgraduate Certificate)
Universidad de Granada - Campus de Fuentenueva, Espanha
"ACTIVIDAD ANTIOXIDANTE Y CARACTERIZACIÓN POR HPLC-ESI-TOF-MS DE COMPUESTOS FENÓLICOS CONTENIDOS EN EXTRACTOS METANÓLICOS DE VEGETALES DE LA FAMILIA SOLANACEAE" (TESE/DISSERTAÇÃO)
2009/06/09
Concluído
 Biología (Licence)
Universidad de Granada - Campus de Fuentenueva, Espanha
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/07/01 - 2021/06/30 Pós-doutorado (Investigação) Universidad de Granada, Espanha
Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto, Portugal
(...)
2013/10/01 - 2018/01/09 Investigador (Investigação) Universidad de Granada - Campus de Fuentenueva, Espanha
Universidad de Granada - Campus de Fuentenueva, Espanha
2008/10/01 - 2010/06/30 Estagiário de Investigação (Investigação) Fundación Pública Andaluza para la investigación Biosanitaria Andalucía Oriental, Espanha
Hospital General Básico de Motril, Espanha
Produções

Publicações

Artigo em revista
  1. Ana Margarida Silva; Diana Pinto; Iva Fernandes; Victor de Freitas; María de la Luz Cádiz-Gurrea; Paulo Costa; Cristina Delerue-Matos; Francisca Rodrigues. "An Insight into Kiwiberry Leaf Valorization: Phenolic Composition, Bioactivity and Health Benefits". Molecules (2021): https://doi.org/10.3390/molecules26082314.
    10.3390/molecules26082314
  2. Álvaro Fernández-Ochoa; Francisco Javier Leyva-Jiménez; María De la Luz Cádiz-Gurrea; Sandra Pimentel-Moral; Antonio Segura-Carretero. "The Role of High-Resolution Analytical Techniques in the Development of Functional Foods". International Journal of Molecular Sciences 22 6 (2021): 3220-3220. https://doi.org/10.3390/ijms22063220.
    10.3390/ijms22063220
  3. María de la Luz Cádiz-Gurrea; Diana Pinto; Cristina Delerue-Matos; Francisca Rodrigues. "Olive Fruit and Leaf Wastes as Bioactive Ingredients for Cosmetics—A Preliminary Study". Antioxidants (2021): https://doi.org/10.3390/antiox10020245.
    10.3390/antiox10020245
  4. de la Luz Cádiz-Gurrea, M.; Sinan, K.I.; Zengin, G.; Bene, K.; Etienne, O.K.; Leyva-Jiménez, F.J.; Fernández-Ochoa, Á.; et al. "Bioactivity assays, chemical characterization, ADMET predictions and network analysis of Khaya senegalensis A. Juss (Meliaceae) extracts". Food Research International 139 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85098466181&partnerID=MN8TOARS.
    10.1016/j.foodres.2020.109970
  5. Pinto, D.; Cádiz-Gurrea, M.D.L.L.; Garcia, J.; Saavedra, M.J.; Freitas, V.; Costa, P.; Sarmento, B.; Delerue-Matos, C.; Rodrigues, F.. "From soil to cosmetic industry: Validation of a new cosmetic ingredient extracted from chestnut shells". Sustainable Materials and Technologies 29 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85108501727&partnerID=MN8TOARS.
    10.1016/j.susmat.2021.e00309
  6. Salehi, B.; Quispe, C.; Butnariu, M.; Sarac, I.; Marmouzi, I.; Kamle, M.; Tripathi, V.; et al. "Phytotherapy and food applications from Brassica genus". Phytotherapy Research (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85101966769&partnerID=MN8TOARS.
    10.1002/ptr.7048
  7. Pinto, D.; Cádiz-Gurrea, M.D.L.L.; Vallverdú-Queralt, A.; Delerue-Matos, C.; Rodrigues, F.. "Castanea sativa shells: A review on phytochemical composition, bioactivity and waste management approaches for industrial valorization". Food Research International 144 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85104596943&partnerID=MN8TOARS.
    10.1016/j.foodres.2021.110364
  8. Ibrahime Sinan, K.; Aktumsek, A.; de la Luz Cádiz-Gurrea, M.; Leyva-Jiménez, F.J.; Fernández-Ochoa, Á.; Segura-Carretero, A.; Glamocilja, J.; et al. "A Prospective of Multiple Biopharmaceutical Activities of Procyanidins-Rich Uapaca togoensis Pax Extracts: HPLC-ESI-TOF-MS Coupled with Bioinformatics Analysis". Chemistry and Biodiversity (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85108354561&partnerID=MN8TOARS.
    10.1002/cbdv.202100299
  9. María Villegas-Aguilar; María Cádiz-Gurrea; David Arráez-Román; Antonio Segura-Carretero. "Comparative Evaluation of the Total Antioxidant Capacities of Plant Polyphenols in Different Natural Sources". Medical Sciences Forum 2 1 (2020): 1-1. https://doi.org/10.3390/CAHD2020-08614.
    10.3390/CAHD2020-08614
  10. María del Carmen Villegas-Aguilar; Francisco Javier Leyva-Jiménez; María de la Luz Cádiz-Gurrea; Antonio Segura-Carretero; David Arráez-Román. "Comprehensive Analysis of Antioxidant Compounds from Lippia citriodora and Hibiscus sabdariffa Green Extracts Attained by Response Surface Methodology". Antioxidants 9 12 (2020): 1175-1175. https://doi.org/10.3390/antiox9121175.
    10.3390/antiox9121175
  11. Francisco Javier Leyva-Jiménez; Jesús Lozano-Sánchez; María de la Luz Cádiz-Gurrea; Álvaro Fernández-Ochoa; David Arráez-Román; Antonio Segura-Carretero. "Spray-Drying Microencapsulation of Bioactive Compounds from Lemon Verbena Green Extract". Foods (2020): https://doi.org/10.3390/foods9111547.
    10.3390/foods9111547
  12. Francisco Javier Leyva-Jiménez; Jesús Lozano-Sánchez; Álvaro Fernández-Ochoa; María de la Luz Cádiz-Gurrea; David Arráez-Román; Antonio Segura-Carretero. "Optimized Extraction of Phenylpropanoids and Flavonoids from Lemon Verbena Leaves by Supercritical Fluid System Using Response Surface Methodology". Foods 9 7 (2020): 931-931. https://doi.org/10.3390/foods9070931.
    10.3390/foods9070931
  13. María de la Luz Cádiz-Gurrea; Álvaro Fernández-Ochoa; Francisco Javier Leyva-Jiménez; Noelia Guerrero-Muñoz; María del Carmen Villegas Aguilar; Sandra Pimentel-Moral; Fernando Ramos-Escudero; Antonio Segura-Carretero. "LC-MS and Spectrophotometric Approaches for Evaluation of Bioactive Compounds from Peru Cocoa By-Products for Commercial Applications". Molecules (2020): https://www.mdpi.com/1420-3049/25/14/3177.
    10.3390/molecules25143177
  14. Álvaro Fernández-Ochoa; Rosa Quirantes-Piné; Isabel Borrás-Linares; María de la Luz Cádiz-Gurrea; Marta E. Alarcón Riquelme; Carl Brunius; Antonio Segura-Carretero. "A Case Report of Switching from Specific Vendor-Based to R-Based Pipelines for Untargeted LC-MS Metabolomics". Metabolites (2020): https://doi.org/10.3390/metabo10010028.
    10.3390/metabo10010028
  15. María del Carmen Villegas Aguilar; Álvaro Fernández-Ochoa; María de la Luz Cádiz-Gurrea; Sandra Pimentel-Moral; Jesús Lozano Sánchez; David Arraez-Roman; Antonio Segura-Carretero. "Pleiotropic Biological Effects of Dietary Phenolic Compounds and their Metabolites on Energy Metabolism, Inflammation and Aging". Molecules (2020): https://www.mdpi.com/1420-3049/25/3/596.
    10.3390/molecules25030596
  16. Salehi, B.; Konovalov, D.A.; Fru, P.; Kapewangolo, P.; Peron, G.; Ksenija, M.S.; Cardoso, S.M.; et al. "Areca catechu—From farm to food and biomedical applications". Phytotherapy Research (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85081931635&partnerID=MN8TOARS.
    10.1002/ptr.6665
  17. de la Luz Cádiz-Gurrea, M.; Zengin, G.; Leyva-Jiménez, F.J.; Fernández-Ochoa, Á.; Sinan, K.I.; Cakilcioglu, U.; Babacan, E.Y.; et al. "A comparative assessment of biological activities of Gundelia dersim Miller and Gundelia glabra Vitek, Yüce & Ergin extracts and their chemical characterization via HPLC-ESI-TOF-MS". Process Biochemistry 94 (2020): 143-151. http://www.scopus.com/inward/record.url?eid=2-s2.0-85083698584&partnerID=MN8TOARS.
    10.1016/j.procbio.2020.04.002
  18. Cádiz-Gurrea, M.D.L.L.; Villegas-Aguilar, M.D.C.; Leyva-Jiménez, F.J.; Pimentel-Moral, S.; Fernández-Ochoa, Á.; Alañón, M.E.; Segura-Carretero, A.. "Revalorization of bioactive compounds from tropical fruit by-products and industrial applications by means of sustainable approaches". Food Research International 138 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85094098713&partnerID=MN8TOARS.
    10.1016/j.foodres.2020.109786
  19. Fernández-Ochoa, Á.; Brunius, C.; Borrás-Linares, I.; Quirantes-Piné, R.; Cádiz-Gurrea, M.D.L.L.; Alarcón Riquelme, M.E.; Segura-Carretero, A.. "Metabolic Disturbances in Urinary and Plasma Samples from Seven Different Systemic Autoimmune Diseases Detected by HPLC-ESI-QTOF-MS". Journal of Proteome Research 19 8 (2020): 3220-3229. http://www.scopus.com/inward/record.url?eid=2-s2.0-85088435065&partnerID=MN8TOARS.
    10.1021/acs.jproteome.0c00179
  20. Pinto, D.; De La Luz Cádiz-Gurrea, M.; Sut, S.; Ferreira, A.S.; Leyva-Jimenez, F.J.; Dall'acqua, S.; Segura-Carretero, A.; Delerue-Matos, C.; Rodrigues, F.. "Valorisation of underexploited Castanea sativa shells bioactive compounds recovered by supercritical fluid extraction with CO2: A response surface methodology approach". Journal of CO2 Utilization 40 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85088036157&partnerID=MN8TOARS.
    10.1016/j.jcou.2020.101194
  21. Mariló Olivares-Vicente; Noelia Sánchez-Marzo; José Antonio Encinar; María de la Luz Cádiz-Gurrea; Jesús Lozano-Sánchez; Antonio Segura-Carretero; David Arraez-Roman; et al. "The Potential Synergistic Modulation of AMPK by Lippia citriodora Compounds as a Target in Metabolic Disorders". Nutrients 11 12 (2019): 2961-2961. https://doi.org/10.3390/nu11122961.
    10.3390/nu11122961
  22. María Luz Cádiz-Gurrea; Gokhan Zengin; Ozlem Kayacik; Devina Lobine; Mohamad Fawzi Mahomoodally; Francisco Javier Leyva-Jiménez; Antonio Segura-Carretero. "Innovative perspectives on Pulicaria dysenterica extracts: phyto-pharmaceutical properties, chemical characterization and multivariate analysis". Journal of the Science of Food and Agriculture (2019): https://doi.org/10.1002/jsfa.9875.
    10.1002/jsfa.9875
  23. Bahare Salehi; Zeliha; Bilge Sener; Mehtap Kilic; Arun K. Jugran; Nunziatina De Tommasi; Chiara Sinisgalli; et al. "Berberis Plants—Drifting from Farm to Food Applications, Phytotherapy, and Phytopharmacology". Foods (2019): https://www.mdpi.com/2304-8158/8/10/522.
    10.3390/foods8100522
  24. Noelia Sánchez-Marzo; Jesús Lozano-Sánchez; María de la Luz Cádiz-Gurrea; María Herranz-López; Vicente Micol; Antonio Segura-Carretero. "Relationships Between Chemical Structure and Antioxidant Activity of Isolated Phytocompounds from Lemon Verbena". Antioxidants (2019): https://doi.org/10.3390/antiox8080324.
    10.3390/antiox8080324
  25. Francisco Javier Leyva-Jiménez; Jesús Lozano-Sánchez; María de la Luz Cádiz-Gurrea; David Arráez-Román; Antonio Segura-Carretero. "Functional Ingredients based on Nutritional Phenolics. A Case Study against Inflammation: Lippia Genus". Nutrients 11 7 (2019): 1646-1646. https://doi.org/10.3390/nu11071646.
    10.3390/nu11071646
  26. María de la Luz Cádiz-Gurrea; Ignacio Fernández de las Nieves; Luis Manuel Aguilera Saez; Salvador Fernández-Arroyo; Laurence Legeai-Mallet; Mohamed Bouaziz; Antonio Segura-Carretero. "Bioactive Compounds from Theobroma cacao: Effect of Isolation and Safety Evaluation". Plant Foods for Human Nutrition 74 1 (2019): 40-46. https://doi.org/10.1007/s11130-018-0694-x.
    10.1007/s11130-018-0694-x
  27. Francisco Javier Leyva-Jimenez; Jesus Lozano-Sanchez; Isabel Borras-Linares; María de la Luz Cadiz-Gurrea; Elaheh Mahmoodi-Khaledi. "Potential antimicrobial activity of honey phenolic compounds against Gram positive and Gram negative bacteria". LWT 101 (2019): 236-245. https://doi.org/10.1016/j.lwt.2018.11.015.
    10.1016/j.lwt.2018.11.015
  28. María de la Luz Cádiz-Gurrea; Jesús Lozano-Sánchez; Álvaro Fernández-Ochoa; Antonio Segura-Carretero. "Enhancing the Yield of Bioactive Compounds from Sclerocarya birrea Bark by Green Extraction Approaches". Molecules (2019): https://www.mdpi.com/1420-3049/24/5/966.
    10.3390/molecules24050966
  29. Salehi, B.; Iriti, M.; Vitalini, S.; Antolak, H.; Pawlikowska, E.; Kregiel, D.; Sharifi-Rad, J.; et al. "Euphorbia-derived natural products with potential for use in health maintenance". Biomolecules 9 8 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85070773450&partnerID=MN8TOARS.
    10.3390/biom9080337
  30. de la Luz Cádiz-Gurrea, M.; Micol, V.; Joven, J.; Segura-Carretero, A.; Fernández-Arroyo, S.. "Different behavior of polyphenols in energy metabolism of lipopolysaccharide-stimulated cells". Food Research International 118 (2019): 96-100. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041947185&partnerID=MN8TOARS.
    10.1016/j.foodres.2018.02.027
  31. Marco Ciulu; María de la Luz Cádiz-Gurrea; Antonio Segura-Carretero. "Extraction and Analysis of Phenolic Compounds in Rice: A Review". Molecules (2018): http://www.mdpi.com/1420-3049/23/11/2890.
    10.3390/molecules23112890
  32. Cádiz-Gurrea, M.D.L.L.; Olivares-Vicente, M.; Herranz-López, M.; Román-Arráez, D.; Fernández-Arroyo, S.; Micol, V.; Segura-Carretero, A.. "Bioassay-guided purification of Lippia citriodora polyphenols with AMPK modulatory activity". Journal of Functional Foods 46 (2018): 514-520. http://www.scopus.com/inward/record.url?eid=2-s2.0-85047317115&partnerID=MN8TOARS.
    10.1016/j.jff.2018.05.026
  33. Salehi, B.; Valussi, M.; Jugran, A.K.; Martorell, M.; Ramírez-Alarcón, K.; Stojanovic-Radic, Z.Z.; Antolak, H.; et al. "Nepeta species: From farm to food applications and phytotherapy". Trends in Food Science and Technology 80 (2018): 104-122. http://www.scopus.com/inward/record.url?eid=2-s2.0-85051648983&partnerID=MN8TOARS.
    10.1016/j.tifs.2018.07.030
  34. López, M.; Blasco, L.; Gato, E.; Perez, A.; Fernández-Garcia, L.; Martínez-Martinez, L.; Fernández-Cuenca, F.; et al. "Response to bile salts in clinical strains of Acinetobacter baumannii lacking the adeABC efflux pump: Virulence associated with quorum sensing". Frontiers in Cellular and Infection Microbiology 7 MAY (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85027518561&partnerID=MN8TOARS.
    10.3389/fcimb.2017.00143
  35. Cádiz-Gurrea, M.L.; Borrás-Linares, I.; Lozano-Sánchez, J.; Joven, J.; Fernández-Arroyo, S.; Segura-Carretero, A.. "Cocoa and grape seed byproducts as a source of antioxidant and anti-inflammatory proanthocyanidins". International Journal of Molecular Sciences 18 2 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85012195873&partnerID=MN8TOARS.
    10.3390/ijms18020376
  36. López, M.; Mayer, C.; Fernández-García, L.; Blasco, L.; Muras, A.; Ruiz, F.M.; Bou, G.; et al. "Quorum sensing network in clinical strains of A. baumannii: AidA is a new quorum quenching enzyme". PLoS ONE 12 3 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85016077838&partnerID=MN8TOARS.
    10.1371/journal.pone.0174454
  37. Fernández-Arroyo, S.; Huete-Toral, F.; De Lara, M.J.P.; De La Luz Cádiz-Gurrea, M.; Legeai-Mallet, L.; Micol, V.; Segura-Carretero, A.; Joven, J.; Pintor, J.. "The impact of polyphenols on chondrocyte growth and survival: A preliminary report". Food and Nutrition Research 59 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84943614151&partnerID=MN8TOARS.
    10.3402/fnr.v59.29311
  38. Cádiz-Gurrea, M.L.; Fernández-Arroyo, S.; Segura-Carretero, A.. "Pine bark and green tea concentrated extracts: Antioxidant activity and comprehensive characterization of bioactive compounds by HPLC-ESI-QTOF-MS". International Journal of Molecular Sciences 15 11 (2014): 20382-20402. http://www.scopus.com/inward/record.url?eid=2-s2.0-84910124337&partnerID=MN8TOARS.
    10.3390/ijms151120382
  39. Morales-Soto, A.; García-Salas, P.; Rodríguez-Pérez, C.; Jiménez-Sánchez, C.; Cádiz-Gurrea, M.D.L.L.; Segura-Carretero, A.; Fernández-Gutiérrez, A.. "Antioxidant capacity of 44 cultivars of fruits and vegetables grown in Andalusia (Spain)". Food Research International 58 (2014): 35-46. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893831508&partnerID=MN8TOARS.
    10.1016/j.foodres.2014.01.050
  40. Cádiz-Gurrea, M.L.; Lozano-Sanchez, J.; Contreras-Gámez, M.; Legeai-Mallet, L.; Fernández-Arroyo, S.; Segura-Carretero, A.. "Isolation, comprehensive characterization and antioxidant activities of Theobroma cacao extract". Journal of Functional Foods 10 (2014): 485-498. http://www.scopus.com/inward/record.url?eid=2-s2.0-84910117941&partnerID=MN8TOARS.
    10.1016/j.jff.2014.07.016
  41. Villar, M.; Cano, M.E.; Gato, E.; Garnacho-Montero, J.; Miguel Cisneros, J.; Ruíz De Alegría, C.; Fernández-Cuenca, F.; et al. "Epidemiologic and clinical impact of acinetobacter baumannii colonization and infection: A reappraisal". Medicine (United States) 93 5 (2014): 202-210. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907960520&partnerID=MN8TOARS.
    10.1097/MD.0000000000000036
  42. Cádiz-Gurrea, M.D.L.L.; Fernández-Arroyo, S.; Joven, J.; Segura-Carretero, A.. "Comprehensive characterization by UHPLC-ESI-Q-TOF-MS from an Eryngium bourgatii extract and their antioxidant and anti-inflammatory activities". Food Research International 50 1 (2013): 197-204. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868579859&partnerID=MN8TOARS.
    10.1016/j.foodres.2012.09.038
Capítulo de livro
  1. Fernández-Ochoa, Á.; Leyva-Jiménez, F.J.; Pimentel-Moral, S.; del Carmen Villegas-Aguilar, M.; Alañón, M.E.; Segura-Carretero, A.; de la Luz Cádiz-Gurrea, M.. "Revalorisation of Agro-Industrial Wastes into High Value-Added Products". 229-245. 2021.
    10.1007/978-3-030-61837-7_14
  2. Rodrigues, F.; Cádiz-Gurrea, M.L.; Nunes, M.A.; Pinto, D.; Vinha, A.F.; Linares, I.B.; Oliveira, M.B.P.P.; Carretero, A.S.. "Cosmetics". 393-427. 2018.
  3. de la Luz Cádiz Gurrea, M.; Pardo, E.A.; Román, D.A.; Arroyo, S.F.; Molina, V.M.; Roche, E.; Carretero, A.S.. "Bioactive compounds from lippia citriodora: Application in diseases prevention". 183-220. 2017.
  4. De La Luz Cádiz-Gurrea, M.; Fernández-Arroyo, S.; Joven, J.; Menéndez, J.A.; Micol, V.; Segura-Carretero, A.. "Proanthocyanidins in agro-industrial by-products: Health benefits". 63-114. 2015.

Outros

Outra produção
  1. Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia. 2021. Martin, L.; Kaci, N.; Benoist-Lasselin, C.; Mondoloni, M.; Decaudaveine, S.; Estibals, V.; Cornille, M.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85102609371&partnerID=MN8TOARS.
    10.1101/2021.02.18.431801
Atividades

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2015/10/01 - 2019/09/30 Organización de las I-IV Jornadas/I-II Congreso Nacional de Investigadores en Formación: Fomentando la interdisciplinariedad (2019/06/25 - 2019/06/27)
Congresso (Coorganizador)
 Universidad de Granada, Espanha
Distinções

Prémio

2017 Best Poster Award 1st Prize