Simon Sedej. Works in the area(s) of Medical and Health Sciences with emphasis on Basic Medicine with emphasis on Physiology. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: aging; heart failure; autophagy; caloric restriction mimetics; calcium homeostasis; animal models; .

Identificação pessoal

Nome completo
Simon Sedej

Nomes de citação

  • Sedej, Simon

Identificadores de autor

Ciência ID
BD14-88E4-59EE
ORCID iD
0000-0002-4419-6821

Telefones

Telefone
  • (Österreich) 43 Ext.: 3163857274 (Profissional)

Moradas

  • Auenbruggerplatz 15, 8036, Graz, Graz, Áustria (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Fisiologia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Esloveno (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Alemão Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Italiano Utilizador elementar (A2) Utilizador independente (B1) Utilizador elementar (A2) Utilizador independente (B2) Utilizador elementar (A1)

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2015/10/01 - Atual Professor Associado (Docente Universitário) Medizinische Universität Graz, Áustria

Bolsa

Designação Financiadores
2023/02/01 - 2028/01/31 Vascular health in aging and disease
VASC-HEALTH
Investigador responsável
Em curso
2023/03/01 - 2026/02/28 Integrating exercise and NAD+ metabolism to reduce cardiometabolic risk
INTERACD
Investigador responsável
Em curso
2017/05 - 2020/10 Metabolic Therapy for Managing Diastolic Heart Failure
I 3301
 Austrian Funding Agency (FWF)
2015/02 - 2018/01 Cardioprotective mechanisms in aging
P 27637
 Austrian Funding Agency (FWF)

Publicações

Artigo em revista
  1. Abdellatif, M.; Madeo, F.; Sedej, S.; Kroemer, G.. "Antagonistic pleiotropy: the example of cardiac insulin-like growth factor signaling, which is essential in youth but detrimental in age". Expert Opinion on Therapeutic Targets 27 2 (2023): 87-90. http://www.scopus.com/inward/record.url?eid=2-s2.0-85148455605&partnerID=MN8TOARS.
    10.1080/14728222.2023.2178420
  2. Semeraro, M.D.; Beltrami, A.P.; Kharrat, F.; Almer, G.; Sedej, S.; Renner, W.; Gruber, H.-J.; Curcio, F.; Herrmann, M.. "The impact of moderate endurance exercise on cardiac telomeres and cardiovascular remodeling in obese rats". Frontiers in Cardiovascular Medicine 9 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85146572709&partnerID=MN8TOARS.
    10.3389/fcvm.2022.1080077
  3. Natasa Djalinac; Ewald Kolesnik; Heinrich Maechler; Susanne Scheruebel-Posch; Brigitte Pelzmann; Peter P Rainer; Ines Foessl; et al. "miR-1183 Is a Key Marker of Remodeling upon Stretch and Tachycardia in Human Myocardium". International Journal of Molecular Sciences (2022): https://www.mdpi.com/1422-0067/23/13/6962.
    10.3390/ijms23136962
  4. "Metabolic therapy for managing heart failure with preserved ejection fraction.". Journal of molecular and cellular cardiology (2022): https://doi.org/10.1016/j.yjmcc.2022.04.009.
    10.1016/j.yjmcc.2022.04.009
  5. "Basal oxidation of conserved cysteines modulates cardiac titin stiffness and dynamics.". Redox biology (2022): https://europepmc.org/articles/PMC8971355.
    10.1016/j.redox.2022.102306
  6. "Effects of Atrial Fibrillation on the Human Ventricle.". Circulation research (2022): https://doi.org/10.1161/CIRCRESAHA.121.319718.
    10.1161/circresaha.121.319718
  7. Abdellatif, M.; Madeo, F.; Kroemer, G.; Sedej, S.. "Spermidine overrides INSR (insulin receptor)-IGF1R (insulin-like growth factor 1 receptor)-mediated inhibition of autophagy in the aging heart". Autophagy 18 10 (2022): 2500-2502. http://www.scopus.com/inward/record.url?eid=2-s2.0-85133716509&partnerID=MN8TOARS.
    10.1080/15548627.2022.2095835
  8. Tarkhnishvili, A.; Koentges, C.; Pfeil, K.; Gollmer, J.; Byrne, N.J.; Vosko, I.; Lueg, J.; et al. "Effects of Short Term Adiponectin Receptor Agonism on Cardiac Function and Energetics in Diabetic db/db Mice". Journal of Lipid and Atherosclerosis 11 2 (2022): 161-177. http://www.scopus.com/inward/record.url?eid=2-s2.0-85131640998&partnerID=MN8TOARS.
    10.12997/jla.2022.11.2.161
  9. Abdellatif, M.; Bugger, H.; Kroemer, G.; Sedej, S.. "NAD+ and Vascular Dysfunction: From Mechanisms to Therapeutic Opportunities". Journal of Lipid and Atherosclerosis 11 2 (2022): 111-132. http://www.scopus.com/inward/record.url?eid=2-s2.0-85131306961&partnerID=MN8TOARS.
    10.12997/jla.2022.11.2.111
  10. Abdellatif, M.; Eisenberg, T.; Heberle, A.M.; Thedieck, K.; Kroemer, G.; Sedej, S.. "Cardiac PI3K p110a attenuation delays aging and extends lifespan". Cell Stress 6 8 (2022): 72-75. http://www.scopus.com/inward/record.url?eid=2-s2.0-85141244478&partnerID=MN8TOARS.
    10.15698/cst2022.08.270
  11. Koser, F.; Hobbach, A.J.; Abdellatif, M.; Herbst, V.; Türk, C.; Reinecke, H.; Krüger, M.; Sedej, S.; Linke, W.A.. "Acetylation and phosphorylation changes to cardiac proteins in experimental HFpEF due to metabolic risk reveal targets for treatment". Life Sciences 309 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85139365292&partnerID=MN8TOARS.
    10.1016/j.lfs.2022.120998
  12. Abdellatif, M.; Trummer-Herbst, V.; Heberle, A.M.; Humnig, A.; Pendl, T.; Durand, S.; Cerrato, G.; et al. "Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity". Circulation 145 25 (2022): 1853-1866. http://www.scopus.com/inward/record.url?eid=2-s2.0-85132455132&partnerID=MN8TOARS.
    10.1161/CIRCULATIONAHA.122.059863
  13. Sedej, S.; Abdellatif, M.. "Response by Sedej and Abdellatif to Letter Regarding Article, "fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity"". Circulation 146 24 (2022): E332-E333. http://www.scopus.com/inward/record.url?eid=2-s2.0-85143993447&partnerID=MN8TOARS.
    10.1161/CIRCULATIONAHA.122.062496
  14. "Spermidine supplementation influences mitochondrial number and morphology in the heart of aged mice.". Journal of anatomy (2021): https://doi.org/10.1111/joa.13618.
    10.1111/joa.13618
  15. "NAD+ Metabolism in Cardiac Health, Aging, and Disease.". Circulation (2021): https://doi.org/10.1161/CIRCULATIONAHA.121.056589.
    10.1161/circulationaha.121.056589
  16. "Targeting Cardiovascular Risk Factors Through Dietary Adaptations and Caloric Restriction Mimetics.". Frontiers in nutrition (2021): https://europepmc.org/articles/PMC8514725.
    10.3389/fnut.2021.758058
  17. "Editorial of Special Issue "Sirtuins in Health and Disease".". International journal of molecular sciences (2021): https://europepmc.org/articles/PMC8150691.
    10.3390/ijms22105054
  18. "Loss of autophagy protein ATG5 impairs cardiac capacity in mice and humans through diminishing mitochondrial abundance and disrupting Ca2+ cycling.". Cardiovascular research (2021): https://doi.org/10.1093/cvr/cvab112.
    10.1093/cvr/cvab112
  19. Abdellatif M; Trummer-Herbst V; Koser F; Durand S; Adão R; Vasques-Nóvoa F; Freundt JK; et al. "Nicotinamide for the treatment of heart failure with preserved ejection fraction.". Science translational medicine (2021): http://europepmc.org/abstract/med/33568522.
    10.1126/scitranslmed.abd7064
  20. Helmstadter KG; Ljubojevic-Holzer S; Wood BM; Taheri KD; Sedej S; Erickson JR; Bossuyt J; Bers DM. "CaMKII and PKA-dependent phosphorylation co-regulate nuclear localization of HDAC4 in adult cardiomyocytes.". Basic research in cardiology (2021): http://europepmc.org/abstract/med/33590335.
    10.1007/s00395-021-00850-2
  21. Tomin, T.; Schittmayer, M.; Sedej, S.; Bugger, H.; Gollmer, J.; Honeder, S.; Darnhofer, B.; et al. "Mass spectrometry-based redox and protein profiling of failing human hearts". International Journal of Molecular Sciences 22 4 (2021): 1-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-85100675806&partnerID=MN8TOARS.
    10.3390/ijms22041787
  22. Semeraro, M.D.; Almer, G.; Kaiser, M.; Zelzer, S.; Meinitzer, A.; Scharnagl, H.; Sedej, S.; Gruber, H.-J.; Herrmann, M.. "The effects of long-term moderate exercise and Western-type diet on oxidative/nitrosative stress, serum lipids and cytokines in female Sprague Dawley rats". European Journal of Nutrition (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85111512774&partnerID=MN8TOARS.
    10.1007/s00394-021-02639-4
  23. Schroeder, S.; Hofer, S.J.; Zimmermann, A.; Pechlaner, R.; Dammbrueck, C.; Pendl, T.; Marcello, G.M.; et al. "Dietary spermidine improves cognitive function". Cell Reports 35 2 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85104086914&partnerID=MN8TOARS.
    10.1016/j.celrep.2021.108985
  24. Klionsky, D.J.; Abdel-Aziz, A.K.; Abdelfatah, S.; Abdellatif, M.; Abdoli, A.; Abel, S.; Abeliovich, H.; et al. "Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1". Autophagy 17 1 (2021): 1-382. http://www.scopus.com/inward/record.url?eid=2-s2.0-85102619204&partnerID=MN8TOARS.
    10.1080/15548627.2020.1797280
  25. Ljubojevic-Holzer S; Herren AW; Djalinac N; Voglhuber J; Morotti S; Holzer M; Wood BM; et al. "CaMKIIdC Drives Early Adaptive Ca2+ Change and Late Eccentric Cardiac Hypertrophy.". Circulation research (2020): http://europepmc.org/abstract/med/32821022.
    10.1161/circresaha.120.316947
  26. Sedej, Simon. "Spermidine supplementation and voluntary activity differentially affect obesity-related structural changes in the mouse lung.". American journal of physiology. Lung cellular and molecular physiology (2020): https://doi.org/10.1152/ajplung.00423.2019.
    10.1152/ajplung.00423.2019
  27. Djalinac N; Ljubojevic-Holzer S; Matzer I; Kolesnik E; Jandl K; Lohberger B; Rainer P; et al. "The role of stretch, tachycardia and sodium-calcium exchanger in induction of early cardiac remodelling.". Journal of cellular and molecular medicine (2020): http://europepmc.org/abstract/med/32573098.
    10.1111/jcmm.15504
  28. Sedej, Simon. "Cardiovascular benefits of intermittent fasting.". Cardiovascular research (2020): https://doi.org/10.1093/cvr/cvaa022.
    10.1093/cvr/cvaa022
  29. Hofer DC; Zirkovits G; Pelzmann HJ; Huber K; Pessentheiner AR; Xia W; Uno K; et al. "N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health.". FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2019): http://europepmc.org/abstract/med/31638418.
    10.1096/fj.201801323r
  30. Sedej, Simon. "Corrigendum to "Cardioprotection by spermidine does not depend on structural characteristics of the myocardial microcirculation in aged mice" [Exp Gerontol 199 (2019) 82-88].". Experimental gerontology (2019): https://doi.org/10.1016/j.exger.2019.05.009.
    10.1016/j.exger.2019.05.009
  31. Sedej, Simon. "The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species.". Nature communications (2019): http://europepmc.org/articles/PMC6381180.
    10.1038/s41467-019-08555-w
  32. Sedej, Simon. "Cardioprotection by spermidine does not depend on structural characteristics of the myocardial microcirculation in aged mice.". Experimental gerontology (2019): https://doi.org/10.1016/j.exger.2019.01.026.
    10.1016/j.exger.2019.01.026
  33. Sedej, Simon. "Cardioprotective effects of autophagy induction in sepsis.". Annals of translational medicine (2018): http://europepmc.org/articles/PMC6291539.
    10.21037/atm.2018.10.23
  34. Sedej, Simon. "Autophagy in Cardiovascular Aging.". Circulation research (2018): https://doi.org/10.1161/CIRCRESAHA.118.312208.
    10.1161/circresaha.118.312208
  35. Sedej, Simon. "The Anti-Cancer Multikinase Inhibitor Sorafenib Impairs Cardiac Contractility by Reducing Phospholamban Phosphorylation and Sarcoplasmic Calcium Transients.". Scientific reports (2018): http://europepmc.org/articles/PMC5871797.
    10.1038/s41598-018-23630-w
  36. Sedej S. "Ketone bodies to the rescue for an aging heart?". Cardiovascular research (2018): http://europepmc.org/abstract/med/29293913.
    10.1093/cvr/cvx218
  37. Schweitzer MK; Wilting F; Sedej S; Dreizehnter L; Dupper NJ; Tian Q; Moretti A; et al. "Suppression of Arrhythmia by Enhancing Mitochondrial Ca2+ Uptake in Catecholaminergic Ventricular Tachycardia Models.". JACC. Basic to translational science (2017): http://europepmc.org/abstract/med/29354781.
    10.1016/j.jacbts.2017.06.008
  38. Sedej, Simon. "Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue.". Cell metabolism (2017): http://europepmc.org/abstract/med/28988821.
    10.1016/j.cmet.2017.09.004
  39. Sedej, Simon. "Dietary spermidine for lowering high blood pressure.". Autophagy (2017): http://europepmc.org/abstract/med/28118075.
    10.1080/15548627.2017.1280225
  40. Sedej, Simon. "Cardioprotection and lifespan extension by the natural polyamine spermidine.". Nature medicine (2016): http://europepmc.org/abstract/med/27841876.
    10.1038/nm.4222
  41. Schipke J; Grimm C; Arnstein G; Kockskämper J; Sedej S; Mühlfeld C. "Cardiomyocyte loss is not required for the progression of left ventricular hypertrophy induced by pressure overload in female mice.". (2016): http://europepmc.org/abstract/med/26990078.
    10.1111/joa.12463
  42. Klionsky DJ; Abdelmohsen K; Abe A; Abedin MJ; Abeliovich H; Acevedo Arozena A; Adachi H; et al. "Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).". (2016): http://europepmc.org/abstract/med/26799652.
    10.1080/15548627.2015.1100356
  43. Klionsky, D.J.; Abdelmohsen, K.; Abe, A.; Abedin, M.J.; Abeliovich, H.; Arozena, A.A.; Adachi, H.; et al. "Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356". Autophagy 12 2 (2016): 443-443. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054826264&partnerID=MN8TOARS.
    10.1080/15548627.2016.1147886
  44. Heinzel FR; Hohendanner F; Jin G; Sedej S; Edelmann F. "Myocardial hypertrophy and its role in heart failure with preserved ejection fraction.". (2015): http://europepmc.org/abstract/med/26183480.
    10.1152/japplphysiol.00374.2015
  45. Drexler, M. K.; Wilting, F.; Dreizehnter, L.; Sedej, S.; Moretti, A.; Priori, S.; Kwon, O.; Gudermann, T.; Schredelseker, J.. "Pharmacological activation of mitochondrial Ca2+ uptake suppresses arrhythmogenic events in CPVT cardiomyocytes". Naunyn-Schmiedebergs Archives of Pharmacology 388 (2015): S34-S34. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000359539100135&KeyUID=WOS:000359539100135.
  46. Sedej, Simon; Schmidt, Albrecht; Denegri, Marco; Walther, Stefanie; Matovina, Marinko; Arnstein, Georg; Gutschi, Eva-Maria; et al. "Subclinical Abnormalities in Sarcoplasmic Reticulum Ca2+ Release Promote Eccentric Myocardial Remodeling and Pump Failure Death in Response to Pressure Overload". Journal of the American College of Cardiology 63 15 (2014): 1569-1579. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000334285900017&KeyUID=WOS:000334285900017.
    10.1016/j.jacc.2013.11.010
  47. Sedej, S.; Matovina, M.; Schmidt, A.; Ljubojevic, S.; Heinzel, F. R.; Negri, S.; Napolitano, C.; et al. "Reduced pressure overload-induced myocardial remodeling in K201-treated mice with the R4496C cardiac ryanodine receptor mutation". Cardiovascular Research 103 (2014): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000343730100301&KeyUID=WOS:000343730100301.
    10.1093/cvr/cvu091.70
  48. Eisenberg, Tobias; Schroeder, Sabrina; Andryushkova, Aleksandra; Pendl, Tobias; Kuettner, Victoria; Bhukel, Anuradha; Marino, Guillermo; et al. "Nucleocytosolic Depletion of the Energy Metabolite Acetyl-Coenzyme A Stimulates Autophagy and Prolongs Lifespan". Cell Metabolism 19 3 (2014): 431-444. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000332395500013&KeyUID=WOS:000332395500013.
    10.1016/j.cmet.2014.02.010
  49. Ljubojevic, Senka; Radulovic, Snjezana; Leitinger, Gerd; Sedej, Simon; Sacherer, Michael; Holzer, Michael; Winkler, Claudia; et al. "Early Remodeling of Perinuclear Ca2+ Stores and Nucleoplasmic Ca2+ Signaling During the Development of Hypertrophy and Heart Failure". Circulation 130 3 (2014): 244-U100. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000339392000010&KeyUID=WOS:000339392000010.
    10.1161/CIRCULATIONAHA.114.008927
  50. Ljubojevic, Senka; Radulovic, Snjezana; Sedej, Simon; Kockskaemper, Jens; Pieske, Burkert. "Alterations of Nuclear Ca2+- Dependent Signalling in Heart Failure". Biophysical Journal 106 2 (2014): 115A-115A. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000337000400585&KeyUID=WOS:000337000400585.
  51. Eisenberg, Tobias; Schroeder, Sabrina; Buettner, Sabrina; Carmona-Gutierrez, Didac; Pendl, Tobias; Andryushkova, Aleksandra; Marino, Guillermo; et al. "A histone point mutation that switches on autophagy". Autophagy 10 6 (2014): 1143-1145. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000336970800015&KeyUID=WOS:000336970800015.
    10.4161/auto.28767
  52. Ljubojevic, S.; Radulovic, S.; Sedej, S.; Sacherer, M.; Kockskaemper, J.; Pieske, B.. "Early alterations of nucleoplasmic Ca2+signalling in cardiac hypertrophy". European Journal of Heart Failure 12 (2013): S47-S47. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000332489100167&KeyUID=WOS:000332489100167.
  53. Sacherer, M.; Ljubojevic, S.; Sedej, S.; Sereinigg, M.; Stiegler, P.; Bisping, E.; Moerth, E. M.; et al. "Angiotensin II increases arrhythmogenity of diastolic Ca2+leak in murine and human cardiomyocytes". European Journal of Heart Failure 12 (2013): S38-S38. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000332489100131&KeyUID=WOS:000332489100131.
  54. Sacherer, Michael; Ljubojevic, Senka; Sedej, Simon; Stiegler, Philipp; Sereinigg, Michael; Groschner, Klaus; Antoons, Gudrun; Pieske, Burkert M.; Heinzel, Frank R.. "TRPC3 Channels in Angiotensin II-Induced Calcium- Dependent Arrhythmias in Mouse and Human Cardiomyocytes". Biophysical Journal 104 2 (2013): 434A-434A. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000316074304212&KeyUID=WOS:000316074304212.
  55. Kirsch, Alexander H.; Smaczny, Nicole; Riegelbauer, Viktoria; Sedej, Simon; Hofmeister, Alexander; Stojakovic, Tatjana; Brodmann, Marianne; et al. "REGULATORY T-CELLS MODULATE NEPHROCALCINOSIS IN MICE". Nephrology Dialysis Transplantation 28 (2013): 406-406. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000319498202241&KeyUID=WOS:000319498202241.
  56. Eller, P.; Kirsch, A.; Smaczny, N.; Sedej, S.; Hofmeister, A.; Stojakovic, T.; Brodmann, M.; et al. "Regulatory T-cells modulate ectopic calcification in nephrocalcinosis and dystrophic cardiac calcinosis". European Heart Journal 34 (2013): 508-508. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000327744603101&KeyUID=WOS:000327744603101.
  57. Kirsch, Alexander H.; Smaczny, Nicole; Riegelbauer, Viktoria; Sedej, Simon; Hofmeister, Alexander; Stojakovic, Tatjana; Goessler, Walter; et al. "Regulatory T Cells Improve Nephrocalcinosis but Not Dystrophic Cardiac Calcinosis in DBA/2 Mice". American Journal of Pathology 183 2 (2013): 382-390. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000322611700007&KeyUID=WOS:000322611700007.
    10.1016/j.ajpath.2013.04.012
  58. Sedej, Simon; Klemen, Masa Skelin; Schlueter, Oliver M.; Rupnik, Marjan Slak. "Rab3a Is Critical for Trapping Alpha-MSH Granules in the High Ca2+-Affinity Pool by Preventing Constitutive Exocytosis". Plos One 8 10 (2013): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000326032600114&KeyUID=WOS:000326032600114.
    10.1371/journal.pone.0078883
  59. Sedej, S.; Schipke, J.; Schmidt, A.; Post, H.; Pieske, B.; Muehlfeld, C.. "Left ventricular hypoinnervation is an early event in response to pressure overload-induced myocardial remodelling". European Journal of Heart Failure 12 (2013): S56-S56. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000332489100208&KeyUID=WOS:000332489100208.
  60. Hohendanner, Felix; Ljubojevic, Senka; MacQuaide, Niall; Sacherer, Michael; Sedej, Simon; Biesmans, Liesbeth; Wakula, Paulina; et al. "Intracellular Dyssynchrony of Diastolic Cytosolic [Ca2+] Decay in Ventricular Cardiomyocytes in Cardiac Remodeling and Human Heart Failure". Circulation Research 113 5 (2013): 527-538. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000323322600011&KeyUID=WOS:000323322600011.
    10.1161/CIRCRESAHA.113.300895
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Capítulo de livro
  1. Eisenberg, T.; Abdellatif, M.; Ljubojevic-Holzer, S.; Sedej, S.. "Effects of physiologic inputs on autophagy". 81-95. 2021.
  2. Sedej, Simon. "Autophagy in cardiovascular health and disease". 2020.
    10.1016/bs.pmbts.2020.04.022

Outros

Outra produção
  1. Conserved cysteines in titin sustain the mechanical function of cardiomyocytes. 2020. Herrero-Galán E; Domínguez F; Martínez-Martín I; Sánchez-González C; Vicente N; Lalaguna L; Bonzón-Kulichenko E; et al. http://europepmc.org/abstract/PPR/PPR210938.
    10.1101/2020.09.05.282913

Prémio

2017 Annual Basic Science Award
Österreichische Kardiologische Gesellschaft, Áustria