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Identificação

Identificação pessoal

Nome completo
Elin Moe

Nomes de citação

  • Moe, Elin

Identificadores de autor

Ciência ID
C011-929F-A332
ORCID iD
0000-0002-7923-1471

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Exatas - Química - Eletroquímica
  • Ciências Exatas - Química - Química Física
  • Ciências Naturais - Ciências Biológicas - Bioquímica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Norueguês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Português Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B1) Utilizador independente (B2) Utilizador independente (B1)
Formação
Grau Classificação
2020/01 - 2020/06
Concluído
StartUp Research - leading scientists into innovation (Pós-Graduação)
Universidade Nova de Lisboa, Portugal
8 ECTS
2002/04/19
Concluído
PhD (Doutoramento)
University of Tromsø - The Arcitic University of Norway - Department of Medical Biology, Noruega
"The molecular basis for cold adaptation of uracil-DNA N-glycosylase from Atlantic cod (Gadus morhua)" (TESE/DISSERTAÇÃO)
PhD
1997/03/10
Concluído
Master of science (Mestrado)
University of Oslo - Division of Biochemistry, Noruega
"Optimisation of induced expression of human parathyroide hormone (hPTH) in Saccharomyces cerevisiae" (TESE/DISSERTAÇÃO)
Master of science
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2018/11/01 - Atual Investigador Contratado (Investigação) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2014/05/01 - 2018/10/31 Pós-doutorado (Investigação) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2012/04/01 - 2014/04/30 Investigador visitante (Investigação) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2004/02/01 - 2012/03/31 Investigador Contratado (Investigação) University of Tromsø - The Arctic University of Norway, Noruega
University of Tromsø - The Arctic University of Norway - Department of Chemistry, Noruega
2009/01/01 - 2009/03/31 Investigador visitante (Investigação) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2007/09/17 - 2007/10/28 Investigador visitante (Investigação) The Norwegian University of Science and Technology (NTNU), Noruega
NTNU - Department of Clinical and Molecular Medicine, Noruega
2005/10/15 - 2006/03/31 Investigador visitante (Investigação) The European Syncrotron Radiation Facility (ESRF), França
The European Syncrotron Radiation Facility (ESRF), França
2003/09/01 - 2004/01/31 Investigador visitante (Investigação) The European Syncrotron Radiation Facility (ESRF), França
The European Syncrotron Radiation Facility (ESRF), França
2002/04/20 - 2004/01/31 Pós-doutorado (Investigação) University of Tromsø - The Arctic University of Norway, Noruega
University of Tromsø - The Arcitic University of Norway - Department of Medical Biology, Noruega

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2019/01/01 - 2023/12/31 Professor Associado Convidado (Docente Universitário) University of Tromsø - The Arctic University of Norway - Department of Chemistry, Noruega
University of Tromsø - The Arctic University of Norway - Department of Chemistry, Noruega

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
1997/08/20 - 2002/04/19 PhD student University of Tromsø - The Arctic University of Norway, Noruega
University of Tromsø - The Arcitic University of Norway - Department of Medical Biology, Noruega
1996/02/01 - 1997/07/31 Consultant and project leader The council of higher technological education in Norway, Noruega
The council of higher technological education in Norway, Noruega
1991/06/15 - 1993/06/14 Vice president The National union for students in higher technological education, Norway, Noruega
Projetos

Bolsa

Designação Financiadores
2023/11/01 - Atual PhD fellowship: The role of Base Excision Repair (BER) and macromolecular damage protection for extreme radiation resistance of Deinococcus radiodurans.
2023.05520.BD
Orientador
Fundação para a Ciência e a Tecnologia, Portugal
Em curso
2020/10 - Atual PhD fellowship: Unveil the structural basis of the complex between the virulence factor SARS-CoV2 Nsp1 and the host DNA polymerase-alpha, a step forward for the development of new antiviral drugs
Orientador
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
FCT - Fundação para a Ciência e a Tecnologia
Em curso
2022/10/01 - 2032/09/30 PI: From trash to treasure - developing proprietary collagenases for transformation of fish waste into high value products.
IOVPoC-2021-10
Investigador responsável
ITQB NOVA and Camera Municipal Oeiras, Portugal
Em curso
2018/01/01 - 2023/12/11 PhD fellowship: Functional insights into repair of oxidation damaged DNA: from gene expression to structural and biophysical properties
FCT/BD/132966/2017
Orientador
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Fundacao para a Ciencia e a Tecnologia (FCT)
Concluído
2018/01/01 - 2023/04/19 PhD fellowship: Deciphering the molecular mechanisms of DNA end-processing in Base Excision Repair (BER)
PD/BD/13548/2018
Orientador
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2022/08 - 2022/08 Project partner: CaboAcid, Investigating the potential effects of ocean acidification on marine carbonate organisms along the Iberian margin coastal upwelling system.
SEA02-019
Investigador
Eurofleets +
2019/09 - 2022/08 Project partner: IMpaCT - Imaging life from Molecules to cells - building knowledge on Cryo-electron microscopy methodologies (800.000 EUR)
Investigador
European Commission
2018/10/01 - 2021/09/30 Project partner: Biosensors and electrochemical bioreactors based on oxidoreductases: design guided by the biophysical characterization of proteins.
PTDC/BIA-BFS/31026/2017
Investigador
Universidade NOVA de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2018/09 - 2021/08 Project partner: Twin to Illuminate Metals in Biology and Biocatalysis through Biospectroscopy (1.000.000 EUR)
Investigador
European Commission
2020/09 - 2020/11 Project partner: Detect - Development of an Easy, fast-Track and Economical Colorimetric Test for autonomous national diagnosis of COVID-19 (FCT): 35.000 EUR.
Investigador
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
FCT - Fundação para a Ciência e a Tecnologia
Concluído
2020/04/01 - 2020/06/30 Instruct-ERIC internship for PhD student: Structure determination of DNA polymerase I (DrPoll) and DrPoll:DNA complex of Deinococcus radiodurans by cryo-EM
PID: 10934
Investigador
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Instruct-ERIC
Concluído
2015/01 - 2019/12 Portuguese partner and principal investigator of Portuguese contribution: MicroMBT - Discovery and training of microbial biocatalysts for biomass conversion using moving bed technology (MBT) (125.000 EUR from FCT)
Investigador
FCT - Fundação para a Ciência e a Tecnologia, Portugal
Norges forskningsråd
2016/01 - 2019/06 Project proposer and principal investigator: DNA repair from bacteria to man - Insights into structural and mechanistic features of Base Excision Repair (BER) initiation (160.000 EUR)
Investigador responsável
Fundação para a Ciência e a Tecnologia
2014/04 - 2018/10 Project proposer and post doc fellow: Towards a better understanding of Base Excision Repair (BER) initiation
SFRH/BPD/97493/2013
Bolseiro de Pós-Doutoramento
FCT - Fundação para a Ciência e a Tecnologia
2007/01 - 2014/12 Project proposer and principal investigator (career grant from the Research Council of Norway): Protein-protein interactions at atomic levels (700.000 EUR)
Investigador responsável
Research Council of Norway (RCN), Noruega
Norges forskningsråd
2012/04 - 2014/03 Project proposer and Marie Curie individual fellowship holder: The role of Base Excision Repair (BER) for extreme radiation and desiccation resistance of Deinococcus radiodurans (200.000 EUR)
Bolseiro de Investigação
European Commission
2010/01 - 2013/10 Project partner: Small Scale Structural Metallomics Project in Deinococcus radiodurans (133.000 EUR)
Investigador
Fundação para a Ciência e a Tecnologia
2010/01 - 2013/06 Project partner: Oxidative stress response mechanisms in Deinococcus radiodurans (90.000 EUR)
Investigador
Fundacao para a Ciencia e a Tecnologia (FCT)
2008/01 - 2012/12 Project proposer and principal investigator: Functional and structural biology studies of DNA repair proteins from the radiation resistant bacterium Deinococcus radiodurans (180.000 EUR)
Investigador responsável
Research Council of Norway (RCN), Noruega
Norges forskningsråd
2008/01 - 2011/03 Project partner: Iron Metabolism Study in Deinococcus radiodurans- Novel strategies (65.000 EUR)
Investigador
Fundação para a Ciência e a Tecnologia
2006/01 - 2010/12 Project proposer and acting principal investigator: Protein - DNA interactions at atomic levels (345.000 EUR)
Investigador
Research Council of Norway (RCN), Noruega
Norges forskningsråd
2002/01 - 2007/12 Project partner: Structural and energetic aspects of protein DNA-recognition (190.000 EUR)
Investigador
Research Council of Norway (RCN), Noruega
Norges forskningsråd

Projeto

Designação Financiadores
2019/01/01 - 2019/12/31 Molecular, Structural and Cellular Microbiology
UID/CBQ/04612/2019
Universidade NOVA de Lisboa, Portugal

Universidade Nova de Lisboa Microbiologia Molecular Estrutural e Celular, Portugal

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em revista
  1. Salgueiro, Bruno A.; Saramago, Margarida; Tully, Mark D.; Issoglio, Federico; Silva, Sara T. N.; Paiva, Ana C. F.; Arraiano, Cecília M.; et al. "SARS-CoV2 Nsp1 is a metal-dependent DNA and RNA endonuclease". BioMetals (2024): http://dx.doi.org/10.1007/s10534-024-00596-z.
    Publicado • 10.1007/s10534-024-00596-z
  2. Kelly Frade; Celia M. Silveira; Bruno A. Salgueiro; Sónia Mendes; Lígia O. Martins; Carlos Frazão; Smilja Todorovic; Elin Moe. "Biochemical, Biophysical, and Structural Analysis of an Unusual DyP from the Extremophile Deinococcus radiodurans". Molecules 29 2 (2024): 358-358. http://dx.doi.org/10.3390/molecules29020358.
    10.3390/molecules29020358
  3. Carlota J.F. Conceição; Bruno A. Salgueiro; Paulo A. Ribeiro; Maria Raposo; Elin Moe. "Advances in the expression and purification of human PARP1: A user-friendly protocol". Protein Expression and Purification (2023): https://doi.org/10.1016/j.pep.2023.106336.
    10.1016/j.pep.2023.106336
  4. Fernandes, Andreia; Williamson, Adele; Matias, Pedro M.; Moe, Elin. "Structure/function studies of the NAD+-dependent DNA ligase from the poly-extremophile Deinococcus radiodurans reveal importance of the BRCT domain for DNA binding". Extremophiles 27 3 (2023): http://dx.doi.org/10.1007/s00792-023-01309-z.
    10.1007/s00792-023-01309-z
  5. Rollo, Filipe; Martins, Guilherme D.; Gouveia, André G.; Ithurbide, Solenne; Servant, Pascale; Romão, Célia V.; Moe, Elin. "Insights into the role of three Endonuclease III enzymes for oxidative stress resistance in the extremely radiation resistant bacterium Deinococcus radiodurans". Frontiers in Microbiology 14 (2023): http://dx.doi.org/10.3389/fmicb.2023.1266785.
    Acesso aberto • 10.3389/fmicb.2023.1266785
  6. Carlota J. F. Conceição; Elin Moe; Paulo A. Ribeiro; Maria Raposo. "Liposome Formulations for the Strategic Delivery of PARP1 Inhibitors: Development and Optimization". Nanomaterials 13 10 (2023): 1613-1613. https://doi.org/10.3390%2Fnano13101613.
    10.3390/nano13101613
  7. Elin Moe. "Disentangling Unusual Catalytic Properties and the Role of the [4Fe-4S] Cluster of Three Endonuclease III from the Extremophile D. radiodurans". Molecules 27 13 (2022): 4270-4270. http://dx.doi.org/10.3390/molecules27134270.
    10.3390/molecules27134270
  8. Caserta, Giorgio; Zuccarello, Lidia; Barbosa, Catarina; Silveira, Célia M.; Moe, Elin; Katz, Sagie; Hildebrandt, Peter; Zebger, Ingo; Todorovic, Smilja. "Unusual structures and unknown roles of FeS clusters in metalloenzymes seen from a resonance Raman spectroscopic perspective". Coordination Chemistry Reviews 452 (2022): 214287. http://dx.doi.org/10.1016/j.ccr.2021.214287.
    10.1016/j.ccr.2021.214287
  9. Elin Moe; Célia M. Silveira; Lidia Zuccarello; Filipe Rollo; Meike Stelter; Salvatore De Bonis; Catharina Kulka-Peschke; et al. "Human endonuclease III/NTH1: focusing on the [4Fe–4S] cluster and the N-terminal domain". Chemical Communications (2022): https://doi.org/10.1039/D2CC03643F.
    10.1039/D2CC03643F
  10. Amaral C; Antunes W; Moe E; Duarte AG; Lima LMP; Santos C; Gomes IL; et al. "A molecular test based on RT-LAMP for rapid, sensitive and inexpensive colorimetric detection of SARS-CoV-2 in clinical samples". Scientific reports (2021): http://europepmc.org/abstract/med/34385527.
    10.1038/s41598-021-95799-6
  11. Fernandes A; Piotrowski Y; Williamson A; Frade K; Moe E. "Studies of multifunctional DNA polymerase I from the extremely radiation resistant Deinococcus radiodurans: Recombinant expression, purification and characterization of the full-length protein and its large fragment.". Protein expression and purification (2021): http://europepmc.org/abstract/med/34175440.
    10.1016/j.pep.2021.105925
  12. Silveira, Célia M.; Moe, Elin; Fraaije, Marco; Martins, Lígia O.; Todorovic, Smilja. "Resonance Raman view of the active site architecture in bacterial DyP-type peroxidases". RSC Advances 10 19 (2020): 11095-11104. http://dx.doi.org/10.1039/d0ra00950d.
    10.1039/d0ra00950d
  13. Sarre, Aili; Stelter, Meike; Rollo, Filipe; De Bonis, Salvatore; Seck, Anna; Hognon, Cécilia; Ravanat, Jean-Luc; et al. "The three Endonuclease III variants of Deinococcus radiodurans possess distinct and complementary DNA repair activities". DNA Repair 78 (2019): 45-59. http://dx.doi.org/10.1016/j.dnarep.2019.03.014.
    10.1016/j.dnarep.2019.03.014
  14. Fonseca, Bruno M.; Silva, Luis; trindade ines de brito; Moe, Elin; matias pedro; Louro, Ricardo O.; Paquete, Catarina M.. "Optimizing electroactive organisms: the influence of orthologous proteins.". Frontiers in Energy Research (2019):
    10.3389/fenrg.2019.00002
  15. Trindade, I.B.; Silva, J.M.; Fonseca, B.M.; Catarino, T.; Fujita, M.; Matias, P.M.; Moe, E.; Louro, R.O.. "Structure and reactivity of a siderophore-interacting protein from the marine bacterium Shewanella reveals unanticipated functional versatility". Journal of Biological Chemistry 294 1 (2019): 157-167. http://www.scopus.com/inward/record.url?eid=2-s2.0-85059495865&partnerID=MN8TOARS.
    10.1074/jbc.RA118.005041
  16. Frade, K.S.T.; Fernandes, A.C.P.; Silveira, C.M.; Fraza-o, C.; Moe, E.. "A novel bacterial class v dye-decolourizing peroxidase from the extremophile Deinococcus radiodurans: Cloning, expression optimization, purification, crystallization, initial characterization and X-ray diffraction analysis". Acta Crystallographica Section F Structural Biology Communications (2018):
    10.1107/S2053230X18008488
  17. Moe, E.; Rollo, F.; Silveira, C.M.; Sezer, M.; Hildebrandt, P.; Todorovic, S.. "Spectroelectrochemical insights into structural and redox properties of immobilized endonuclease III and its catalytically inactive mutant". Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy 188 (2018): 149-154. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021877544&partnerID=MN8TOARS.
    10.1016/j.saa.2017.06.050
  18. Timmins, J.; Moe, E.. "A Decade of Biochemical and Structural Studies of the DNA Repair Machinery of Deinococcus radiodurans: Major Findings, Functional and Mechanistic Insight and Challenges". Computational and Structural Biotechnology Journal 14 (2016): 168-176. http://www.scopus.com/inward/record.url?eid=2-s2.0-84969815928&partnerID=MN8TOARS.
    10.1016/j.csbj.2016.04.001
  19. Trindade, I.B.; Fonseca, B.M.; Matias, P.M.; Louro, R.O.; Moe, E.. "A putative siderophore-interacting protein from the marine bacterium Shewanella frigidimarina NCIMB 400: Cloning, expression, purification, crystallization and X-ray diffraction analysis". Acta Crystallographica Section:F Structural Biology Communications 72 (2016): 667-671. http://www.scopus.com/inward/record.url?eid=2-s2.0-84986325474&partnerID=MN8TOARS.
    10.1107/S2053230X16011419
  20. Pedersen, H.L.; Johnson, K.A.; Mcvey, C.E.; Leiros, I.; Moe, E.. "Structure determination of uracil-DNA N-glycosylase from Deinococcus radiodurans in complex with DNA". Acta Crystallographica Section D: Biological Crystallography 71 (2015): 2137-2149. http://www.scopus.com/inward/record.url?eid=2-s2.0-84944217343&partnerID=MN8TOARS.
    10.1107/S1399004715014157
  21. Niiranen, L.; Lian, K.; Johnson, K.A.; Moe, E.. "Crystal structure of the DNA polymerase III ß subunit (ß-clamp) from the extremophile Deinococcus radiodurans". BMC Structural Biology 15 1 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84949116365&partnerID=MN8TOARS.
    10.1186/s12900-015-0032-6
  22. Moe, E.; Sezer, M.; Hildebrandt, P.; Todorovic, S.. "Surface enhanced vibrational spectroscopic evidence for an alternative DNA-independent redox activation of endonuclease III". Chemical Communications 51 15 (2015): 3255-3257. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929995537&partnerID=MN8TOARS.
    10.1039/c4cc09498k
  23. Sarre, A.; Ökvist, M.; Klar, T.; Hall, D.R.; Smalås, A.O.; McSweeney, S.; Timmins, J.; Moe, E.. "Structural and functional characterization of two unusual endonuclease III enzymes from Deinococcus radiodurans". Journal of Structural Biology 191 2 (2015): 87-99. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937814533&partnerID=MN8TOARS.
    10.1016/j.jsb.2015.05.009
  24. Lian, K.; Leiros, H.K.S.; Moe, E.. "MutT from the fish pathogen Aliivibrio salmonicida is a cold-active nucleotide-pool sanitization enzyme with unexpectedly high thermostability". FEBS Open Bio 5 (2015): 107-116. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923145313&partnerID=MN8TOARS.
    10.1016/j.fob.2015.01.006
  25. Moe, Elin. "Reduced Hydrophobicity of the Minor Groove Intercalation Loop is Critical for Efficient Catalysis by Cold Adapted Uracil-DNA N-Glycosylase from Atlantic". J Thermodyn Catal (2015): https://www.omicsonline.org/open-access/reduced-hydrophobicity-of-the-minor-groove-intercalation-loop-iscritical-for-efficient-catalysis-by-cold-adapted-uracildna-nglycos-2157-7544-1000155.pdf.
    10.4172/2157-7544.1000155
  26. Assefa, N.G.; Niiranen, L.; Johnson, K.A.; Leiros, H.-K.S.; Smalås, A.O.; Willassen, N.P.; Moe, E.. "Structural and biophysical analysis of interactions between cod and human uracil-DNA N-glycosylase (UNG) and UNG inhibitor (Ugi)". Acta Crystallographica Section D: Biological Crystallography 70 8 (2014): 2093-2100. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905482232&partnerID=MN8TOARS.
    10.1107/S1399004714011699
  27. Sarre, A.; Ökvist, M.; Klar, T.; Moe, E.; Timmins, J.. "Expression, purification and crystallization of two endonuclease III enzymes from Deinococcus radiodurans". Acta Crystallographica Section F:Structural Biology Communications 70 (2014): 1688-1692. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925883762&partnerID=MN8TOARS.
    10.1107/S2053230X14024935
  28. Moe, E.; Hall, D.R.; Leiros, I.; Monsen, V.T.; Timmins, J.; McSweeney, S.. "Structure-function studies of an unusual 3-methyladenine DNA glycosylase II (AlkA) from Deinococcus radiodurans". Acta Crystallographica Section D: Biological Crystallography 68 6 (2012): 703-712. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862161117&partnerID=MN8TOARS.
    10.1107/S090744491200947X
  29. Assefa, N.G.; Niiranen, L.; Willassen, N.P.; Smalås, A.; Moe, E.. "Thermal unfolding studies of cold adapted uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua). A comparative study with human UNG". Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology 161 1 (2012): 60-68. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863749247&partnerID=MN8TOARS.
    10.1016/j.cbpb.2011.09.007
  30. Raeder, I.L.U.; Moe, E.; Willassen, N.P.; Smals, A.O.; Leiros, I.. "Structure of uracil-DNA N-glycosylase (UNG) from Vibrio cholerae: Mapping temperature adaptation through structural and mutational analysis". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 66 2 (2010): 130-136. http://www.scopus.com/inward/record.url?eid=2-s2.0-76349093841&partnerID=MN8TOARS.
    10.1107/S1744309109052063
  31. Altermark, B.; Helland, R.; Moe, E.; Willassen, N.P.; Smalås, A.O.. "Structural adaptation of endonuclease I from the cold-adapted and halophilic bacterium Vibrio salmonicida". Acta Crystallographica Section D: Biological Crystallography 64 4 (2008): 368-376. http://www.scopus.com/inward/record.url?eid=2-s2.0-40749097681&partnerID=MN8TOARS.
    10.1107/S0907444908000097
  32. Ræder, I.L.U.; Leiros, I.; Willassen, N.P.; Smalås, A.O.; Moe, E.. "Uracil-DNA N-glycosylase (UNG) from the marine, psychrophilic bacterium Vibrio salmonicida shows cold adapted features. A comparative analysis to Vibrio cholerae uracil-DNA N-glycosylase". Enzyme and Microbial Technology 42 7 (2008): 594-600. http://www.scopus.com/inward/record.url?eid=2-s2.0-42749092978&partnerID=MN8TOARS.
    10.1016/j.enzmictec.2008.02.005
  33. Altermark, B.; Thorvaldsen, S.; Moe, E.; Smalås, A.O.; Willassen, N.P.. "Sequence comparison and environmental adaptation of a bacterial endonuclease". Computational Biology and Chemistry 31 3 (2007): 163-172. http://www.scopus.com/inward/record.url?eid=2-s2.0-34248532200&partnerID=MN8TOARS.
    10.1016/j.compbiolchem.2007.03.003
  34. Altermark, B.; Niiranen, L.; Willassen, N.P.; Smalås, A.O.; Moe, E.. "Comparative studies of endonuclease I from cold-adapted Vibrio salmonicida and mesophilic Vibrio cholerae". FEBS Journal 274 1 (2007): 252-263. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845602192&partnerID=MN8TOARS.
    10.1111/j.1742-4658.2006.05580.x
  35. Leiros, H.-K.S.; Pey, A.L.; Innselset, M.; Moe, E.; Leiros, I.; Steen, I.H.; Martinez, A.. "Structure of phenylalanine hydroxylase from Colwellia psychrerythraea 34H, a monomeric cold active enzyme with local flexibility around the active site and high overall stability". Journal of Biological Chemistry 282 30 (2007): 21973-21986. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547602017&partnerID=MN8TOARS.
    10.1074/jbc.M610174200
  36. Leiros, I.; Nabong, M.P.; Grøsvik, K.; Ringvoll, J.; Haugland, G.T.; Uldal, L.; Reite, K.; et al. "Structural basis for enzymatic excision of N1-methyladenine and N3-methylcytosine from DNA". EMBO Journal 26 8 (2007): 2206-2217. http://www.scopus.com/inward/record.url?eid=2-s2.0-34247269030&partnerID=MN8TOARS.
    10.1038/sj.emboj.7601662
  37. Lorentzen, M.S.; Moe, E.; Jouve, H.M.; Willassen, N.P.. "Cold adapted features of Vibrio salmonicida catalase: Characterisation and comparison to the mesophilic counterpart from Proteus mirabilis". Extremophiles 10 5 (2006): 427-440. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749873395&partnerID=MN8TOARS.
    10.1007/s00792-006-0518-z
  38. Dennis, R.J.; Micossi, E.; McCarthy, J.; Moe, E.; Gordon, E.J.; Kozielski-Stuhrmann, S.; Leonard, G.A.; McSweeney, S.. "Structure of the manganese superoxide dismutase from Deinococcus radiodurans in two crystal forms". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 62 4 (2006): 325-329. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645762297&partnerID=MN8TOARS.
    10.1107/S1744309106008402
  39. Moe, E.; Leiros, I.; Smalås, A.O.; McSweeney, S.. "The crystal structure of mismatch-specific uracil-DNA glycosylase (MUG) from Deinococcus radiodurans reveals a novel catalytic residue and broad substrate specificity". Journal of Biological Chemistry 281 1 (2006): 569-577. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644855115&partnerID=MN8TOARS.
    10.1074/jbc.M508032200
  40. Larsen, A.N.; Moe, E.; Helland, R.; Gjellesvik, D.R.; Willassen, N.P.. "Characterization of a recombinantly expressed proteinase K-like enzyme from a psychrotrophic Serratia sp.". FEBS Journal 273 1 (2006): 47-60. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644878499&partnerID=MN8TOARS.
    10.1111/j.1742-4658.2005.05044.x
  41. Olufsen, M.; Smalås, A.O.; Moe, E.; Brandsdal, B.O.. "Increased flexibility as a strategy for cold adaptation: A comparative molecular dynamics study of cold- and warm-active uracil DNA glycosylase". Journal of Biological Chemistry 280 18 (2005): 18042-18048. http://www.scopus.com/inward/record.url?eid=2-s2.0-23844458318&partnerID=MN8TOARS.
    10.1074/jbc.M500948200
  42. Leiros, I.; Moe, E.; Smalås, A.O.; McSweeney, S.. "Structure of the uracil-DNA N-glycosylase (UNG) from Deinococcus radiodurans". Acta Crystallographica Section D: Biological Crystallography 61 8 (2005): 1049-1056. http://www.scopus.com/inward/record.url?eid=2-s2.0-25144524607&partnerID=MN8TOARS.
    10.1107/S090744490501382X
  43. Moe, E.; Leiros, I.; Riise, E.K.; Olufsen, M.; Lanes, O.; Smalås, A.; Willassen, N.P.. "Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua)". Journal of Molecular Biology 343 5 (2004): 1221-1230. http://www.scopus.com/inward/record.url?eid=2-s2.0-6344242968&partnerID=MN8TOARS.
    10.1016/j.jmb.2004.09.004
  44. Leiros, I.; Moe, E.; Lanes, O.; Smalås, A.O.; Willassen, N.P.. "The structure of uracil-DNA glycosylase from Atlantic cod (Gadus morhua) reveals cold-adaptation features". Acta Crystallographica - Section D Biological Crystallography 59 8 (2003): 1357-1365. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042568932&partnerID=MN8TOARS.
    10.1107/S0907444903011144
  45. Vad, R.; Moe, E.; Saga, K.; Kvinnsland, A.M.V.; Øyen, T.B.. "High-level production of human parathyroid hormone (hPTH) by induced expression in Saccharomyces cerevisiae". Protein Expression and Purification 13 3 (1998): 396-402. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032146039&partnerID=MN8TOARS.
    10.1006/prep.1998.0912
Capítulo de livro
  1. Trindade, Ines de Brito; Moe, Elin; Luro, Richardo. "Siderophore-interacting proteins". In Encyclopedia of Inorganic and Bioinorganic Chemistry. Wiley, 2020.
    Publicado
Poster em conferência
  1. Maria O. Firmino; Trindade, Inês B.; Fonseca, Bruno M; Moe, Elin; Matias, Pedro M; Louro, Ricardo. "Comparative Analysis of Flavocytochrome c Redox Properties in Pathogenic and Non-pathogenic Shewanella Species". Trabalho apresentado em 48th FEBS Congress – Mining biochemistry for human health and well-being, 2024.
  2. Gholami, S.; Rollo, F.; Moe, Elin. "Bioinformatics study of an unusual Endonuclease III enzyme from the extremely radiation resistant bacterium Deinococcus radiodurans". Trabalho apresentado em Cost Action 21115: Young Investigator Meeting, Application of Computational and Biophysical Methods in Investigating [FeS] Clusters Biochemistry,, 2023.
  3. Shakiba Gholami; Rollo, Filipe; Folgosa, Filipe; Todorovic, Smilja; Moe, Elin. Autor correspondente: Moe, Elin. "Unveiling the role of two unusual Endonuclease III enzymes in the extremophile Deinococus radiodurans.". Trabalho apresentado em CA21115 - Iron-sulphur(FeS) clusters: from chemistry toimmunology. Meeting: FeS clustersfrom chemistry to biology., 2023.
  4. Barbosa, Catarina; Silveira, Célia M. ; Rollo, Filipe; Zuccarello, Lidia; Moe, Elin; Timmins,Joanna; Todorovic, Smilja. "A biophysical view of the fe-s clusters in the dna repair enzymes hNTH1 and UvrC". Trabalho apresentado em 1st CA21115 Meeting - FeS clusters from chemistry to biology and beyond, 2023.
  5. Amaral, Catarina; Morais, Inês; da Silva, Sofia M.; Antunes, Wilson; G. Duarte, Américo; Moe, Elin; Miragaia, Maria ; Serrano, Mónica; Pimentel, Catarina. "From lab to field: low cost saliva tests for mass-screening of SARS-CoV-2". Trabalho apresentado em IV International Conference NOVAhealth Chronic Disease and Infection, 2022.
  6. Martins, Guilherme; Gouveia, André G.; Rollo, Filipe; Moe, Elin; Romao, Celia V. "Unveiling the role of Dps and EndoIII for DNA protection and repair in Deinococcus radiodurans upon exposure to genotoxic stress". Trabalho apresentado em 13th International congress on extremophiles, 2022.
  7. Trindade, Ines de Brito; Hernandez, G.; Rollo, F.; Lebégue, E.; Barriére, F.; Vicente, J.e; Moe, Elin; et al. "Structural and functional characterization of FhuF - a ferric-siderophore reductase from E. coli". Trabalho apresentado em FEBS congress, 2022.
  8. Salgueiro, Bruno; Saramago, Margarida; Matos, Rute; T. N. Silva, Sara; Tully, Mark; Issoglio, FM; Matias, Pedro M.; Moe, Elin; Romão, Célia V.. "Unveiling the molecular mechanism of Nsp1 of SARS-CoV2 and its function in the infection process". Trabalho apresentado em 12th ITQB NOVA PhD Students' Meeting - ITQB- UNL, 2022.
  9. Maria O. Firmino; Trindade, Inês B.; Fonseca, Bruno M; Moe, Elin; Matias, Pedro M; Louro, Ricardo. "Is the flavocytochrome c from pathogenic Shewanella different from those of other Shewanella species?". Trabalho apresentado em TIMB3 Final Meeting, 2022.
  10. Fernandes, A.; Butcher, S.; Moe, Elin. "Structure prediction of DNA polymerase I from poly-extremophile Deinococcus radiodurans (DrPoll) by combining single particle cryo-Electron Microscopy and homology modeling.". 2021.
  11. Fernandes, A.; Williamson, A.; Matias, P.M.; Moe, Elin. "Crystallization and X-ray diffraction analysis of C-terminally truncated NAD+dependent DNA ligase from the poly-extremophile Deinococcus radiodurans with ligation activity and reduced DNA binding.". Trabalho apresentado em Diamond-CCP4 Data Collection and Structure Solution Workshop 2021 (online)., 2021.
  12. Fernandes, A.; Butcher, S.; Moe, Elin. Autor correspondente: Moe, Elin. "Structure determination of Deinococcus radiodurans DNA polymerase I (DrPoll) and DrPoll:DNA complex by cryoEM.". Trabalho apresentado em Microscopy at the Frontiers of Science (MFS) (online)., 2021.
  13. Trindade, I.B.; Hernandez, G.; Rollo, F.; Lebégue, E.; Barriére, F.; Vicente, J.B.; Moe, E; et al. "Function without structure: FhuF - a ghost ferric-siderophore reductase from Escherichia coli.". Trabalho apresentado em A special symposium celebrating the 50th anniversary of the Protein Data Bank (online)., 2021.
  14. Trindade, Inês B.; Didier, Inês; Fonseca, Bruno M; Silva, José M.; Catarino, Teresa; Matias, Pedro M; Moe, Elin; Louro, Ricardo. "Metal uptake in Shewanella: exploring the mechanisms of siderophore recycling". Trabalho apresentado em ISMET 7, 2019.
  15. Fonseca, Bruno M; Silva, Luis; Trindade, Inês B.; Moe, Elin; Matias, Pedro M; Louro, Ricardo; M. Paquete, Catarina. "Optimizing electroactive organisms: the effect of orthologous proteins". Trabalho apresentado em ISMET 7, 2019.
  16. M. Paquete, Catarina; Fonseca, Bruno M; Silva, Luis; Trindade, Inês B.; Moe, Elin; Matias, Pedro M; Louro, Ricardo. "Biological electron transfer processes: the effect of orthologous proteins". Trabalho apresentado em Research conference in Cell Biology of Metals: Organismal Biology of Metals and Related Metal Complexes, 2019.
  17. Trindade, Inês B.; Silva, José M.; Fonseca, Bruno M; Catarino, Teresa; Fujita, Masaki; Matias, Pedro M; Moe, Elin; Louro, Ricardo. "Unraveling the mechanisms of ferric-siderophore reduction: The unforeseen versatility of SfSIP, a Siderophore-Interacting Protein from Shewanella frigidimarina". Trabalho apresentado em Gordon Research conference in Cell Biology of Metals: Organismal Biology of Metals and Related Metal Complexes, 2019.
  18. Borges, P.; Gonçalves, C.; Fernandes, A.; Silva, J.P.; Moe, Elin. Autor correspondente: Moe, Elin. "Purification, crystallization and preliminary X-ray diffraction analysis of a novel marine bacterial collagenase.". Trabalho apresentado em The 8th Meeting of Portuguese Synchrotron Radiation Users, 2019.
  19. Rollo, F.; Silveira C.; Borges P.T.; Todorovic S.; Moe, Elin. Autor correspondente: Moe, Elin. "Structural and biophysical study of native and mutated Endonuclease III enzymes from Deinococcus radiodurans.". Trabalho apresentado em The 8th Meeting of Portuguese Synchrotron Radiation Users, 2019.
  20. Trindade, Inês B.; Fonseca, Bruno M; Moe, Elin; Matias, Pedro M; M. Paquete, Catarina; Louro, Ricardo. "Crystalizing iron pathways: Structure and reactivity of metalloproteins". Trabalho apresentado em IACT (CSIC-UGR), 2019.
  21. Rollo, F.; Silveira, C.M.; Moe, Elin; Todorovic, S.. "Perspectives on Endonucleases III from the extremophile Deinococcus radiodurans.". Trabalho apresentado em TIMB3 Kick-off meeting., 2018.
  22. Trindade, Inês B.; Silva, José M.; Fonseca, Bruno M; Catarino, Teresa; Fujita, Masaki; Matias, Pedro M.; Moe, Elin; Louro, Ricardo. "Unforeseen versatility in ferric-siderophore reduction: the structural & functional characterization of SIP, a Siderophore-Interacting protein from Shewanella frigidimarina". Trabalho apresentado em EuroBIC14, 2018.
  23. Rollo, F.; Silveira, C.M.; Borges, P.T.; Moe, Elin; Todorovic, S.. "Endonuclease III and its mutants: a comparative study of catalytic, electrochemical and spectroscopic properties.". Trabalho apresentado em The 14th European Biological Inorganic Chemistry Conference (EuroBIC), 2018.
  24. Frade, K.; Silveira, C.M.; Fernandes, A.; Frazao, C.; Todorovic, S.; Moe, Elin. "Initial X-ray analysis and spectroscopic characterization of a peroxidase from the extremophile Deinococcus radiodurans.". Trabalho apresentado em 7th Meeting of Portuguese Synchrotron Radiation Users, 2018.
  25. Fernandes, A.; Frade, K.; Carrondo, M.A.; Moe, Elin. "Cloning, expression and purification of DNA polymerase A and NAD+-dependent DNA ligase from Deinococcus radiodurans.". Trabalho apresentado em 7th Meeting of Portuguese Synchrotron Radiation Users, 2018.
  26. Gonçalves, C.; Fernandes, A.; Borges, P.; Silva, J.; Moe, Elin. "Recombinant production and crystallization of a novel marine bacterial collagenase.". Trabalho apresentado em 7th Meeting of Portuguese Synchrotron Radiation Users, 2018.
  27. Rollo, F.; Borges, P.; Silveira, C.M.; Todorovic, S.; Moe, Elin. "Structure of two mutated Endonuclease III from Deinococcus radiodurans.". Trabalho apresentado em 7th Meeting of Portuguese Synchrotron Radiation Users, 2018.
  28. Rollo, Filipe; Silveira, Celia; Timmins, Joanna; Todorovic, Smilja; Moe, Elin. "Structure/function analysis of two mutated Endonuclease III enzymes from the extremophile Deinococcus radiodurans". Trabalho apresentado em 19th SFRRI Biennial Meeting, 2018.
    10.1016/j.freeradbiomed.2018.04.372
  29. Frade, Kelly; Fernandes, Andreia; Silveira, Celia; Frazao, Carlos; Todorovic, Smilja; Moe, Elin. "Biophysical and crystallization analysis of a novel peroxidase from Deinococcus radiodurans". Trabalho apresentado em 19th SFRRI Biennial Meeting, 2018.
    10.1016/j.freeradbiomed.2018.04.379
  30. Trindade. I.B.; Rollo, F.; Matias, P.M.; Moe, E; Louro, R.O.. "Structure and function of FhuF, a ferric-siderophore reductase from Escherichia coli with an unusual 2Fe-2S cluster.". Trabalho apresentado em EMBO workshop: Challenges for magnetic resonance in life sciences, 2018.
  31. Trindade, Inês B.; Fonseca, Bruno M; Silva, José M.; Catarino, Teresa; Matias, Pedro M; Moe, Elin; Louro, Ricardo. "Exploring the molecular mechanisms of siderophore recycling in Shewanella". Trabalho apresentado em ISMET6, 2017.
  32. Trindade, I.B.; Fonseca, B.M.; Silva, J.M.; Catarino, T.; Matias, P.M.; Moe, Elin; Louro, R.O.. "Exploring the molecular mechanisms of siderophore recycling in Shewanella.". Trabalho apresentado em 6th General Meeting of the International Society for Microbial Electrochemistry and Technology (ISMET), 2017.
  33. Rollo, F.; Silveira, C.M.; Sezer, M.; Hildebrandt, P.; Todorovic, S.; Moe, Elin. "Spectroelectrochemical insights into structural and redox properties of immobilized Endonuclease III.". Trabalho apresentado em 1st FeSBioNet COST Training School, Understanding the molecular mechanisms of Fe/S protein biogenesis, 2017.
  34. Trindade, I.B.; Fonseca, B.M.; Silva, J.M.; Catarino, T.; Matias, P.M.; Moe, Elin; Louro, R.O.. "The mysteries of microbial iron piracy: A siderophore-interacting protein from Shewanella frigidimarina.". Trabalho apresentado em Practical training course: Chemistry of Metals in Biological systems, 2017.
  35. Trindade, Inês B.; Fonseca, Bruno M; Silva, José M.; Catarino, Teresa; Matias, Pedro M; Moe, Elin; Louro, Ricardo. "The mysteries of microbial iron piracy: A siderophore interacting protein from Shewanella frigidimarina". Trabalho apresentado em FEBS Practical and Lecture Course - Chemistry of metals in biological systems, 2017.
  36. Silva, J.M.; Trindade, I.B.; Fonseca, B.M.; Matias, P.M.; Louro, R.O.; Moe, Elin. "Abstract publication and poster: Silva, J.M., Trindade, I.B., Fonseca, B.M, Matias, P.M., Louro, R.O. & Moe, E. Crystal structural determination of a putative siderophore interacting protein from the marine bacterium Shewanella frigidimarina.". Trabalho apresentado em 6th ENURS-Day Meeting of Synchontron Radiation Users from Portugal, 2017.
  37. Fernandes, A.; Frade, K.; Carrondo, M.A.; Moe, Elin. "Cloning, Expression, Purification and Crystallization of Base Excision Repair (BER) and ROS scavenging enzymes from Deinococcus radiodurans".". Trabalho apresentado em 6th ENURS-Day Meeting of Synchontron Radiation Users from Portugal, 2017.
  38. Caniço, B.; Rollo, F.; Sarre, A.; Lian, K.; Timmins, J.; Carrondo, M.A.; Moe, Elin. "Structure/function studies of Base Excision Repair (BER) enzymes from the extremophile Deinococcus radiodurans.". Trabalho apresentado em 6th ENURS-Day Meeting of Synchontron Radiation Users from Portugal, 2017.
  39. Silva, José M.; Trindade, Inês B.; Fonseca, Bruno M; Matias, Pedro M; Louro, Ricardo; Moe, Elin. "Crystal structural determination of a putative siderophore interacting protein from the marine bacterium Shewanella frigidimarina". Trabalho apresentado em 6th National Meeting of Portuguese Synchrotron Radiation Users (ENURS), 2017.
  40. Trindade, Inês B.; Fonseca, Bruno M; Matias, Pedro M; Louro, Ricardo; Moe, Elin. "Marine iron scavenging: a siderophore interacting protein from the marine bacterium Shewanella frigidimarina". Trabalho apresentado em ENURS2016, 2016.
  41. Trindade, I.B.; Fonseca, B.M.; Matias, P.M.; Louro, R.O.; Moe, Elin. "Marine iron scavenging: a siderophore-interacting protein from the marine bacterium Shewanella frigidimarina.". Trabalho apresentado em 5th National Meeting of Portuguese Synchrotron Radiation Users (ENURS)., 2016.
  42. Moe, Elin; Leiros, I.; Hall, D.; Sarre, A.; Smals, A.O.; McSweeney, S.; Timmins, J.. "Base Excision Repair (BER) in Deinococcus radiodurans.". Trabalho apresentado em Thomas Lindahl conference on DNA repair, 2015.
  43. Lian, K.; Leiros, H.K.S.; Moe, Elin. "MutT from the fish pathogen Aliivibrio salmonicida is a cold active nucleotide pool sanitization enzyme with an unexpectedly high thermostability.". Trabalho apresentado em 4th National Meeting of Portuguese Synchrotron Radiation Users (ENURS)., 2015.
  44. Moe, Elin; Timmins, J.; Hall, D.; Leiros, I.; McSweeney, S.. "Structure-function studies of DNA repair proteins from Deinococcus radiodurans.". Trabalho apresentado em the 4th International Conference on Structural Genomics, ICSG 2006., 2006.
  45. Moe, Elin; Leiros, I.; Smalas, A.O.; McSweeney, S.. "Structure determination of mismatch specific uracil-DNA glycosylase (MUG) from the radiation resistant bacteria Deinococcus radiodurans.". Trabalho apresentado em The VI European Protein science meeting, Barcelona, Spain., 2005.
Pré-impressão
  1. Inês B. Trindade; Bruno M. Fonseca; Teresa Catarino; Pedro M. Matias; Elin Moe; Ricardo O. Louro. "Flavin-containing siderophore-interacting protein ofShewanella putrefaciensDSM 9451 reveals substrate specificity in ferric-siderophore reduction". 2024. https://doi.org/10.1101/2024.05.13.594011.
    10.1101/2024.05.13.594011
  2. I.B. Trindade; F. Rollo; S. Todorovic; T. Catarino; E. Moe; P.M. Matias; M. Piccioli; R.O. Louro. "The structure of a novel ferredoxin FhuF, a ferric-siderophore reductase from E. coli K-12 with a novel 2Fe-2S cluster coordination". 2023. https://doi.org/10.1101/2023.07.04.547673.
    10.1101/2023.07.04.547673
Recurso online
  1. Salgueiro, B.A.; Frade, K.S.T.; Frazao, C.; Moe, Elin. Crystal Structure determination of Dye-decolorizing Peroxidase (DyP) from Deinoccoccus radiodurans. 2023. https://www.rcsb.org/structure/8RE2.
  2. Salgueiro, B.A.; Frade, K.; Frazao, C.; Matias, P.; Moe, Elin. Crystal Structure determination of Dye-decolorizing Peroxidase (DyP) mutant M190G from Deinoccoccus radiodurans. 2023. https://www.rcsb.org/structure/8RE3.
  3. Trindade, I.B.; Matias, P.M.; Moe, Elin; Louro, R.O.. Ferric-siderophore reduction in Shewanella biscestrii: Structural and functional characterization of SbiSIP reveals unforeseen specificity. 2023. https://www.rcsb.org/structure/unreleased/8C4L.
  4. Borges, Patricia T.; Rollo, F.,; Moe, Elin. Autor correspondente: Moe, Elin. Crystal structure of Deinococcus radiodurans Endonuclease III-1 Y100L variant. 2022. https://www.rcsb.org/structure/8A5C.
  5. Borges, Patricia T.; Rollo, F.,; Moe, Elin. Autor correspondente: Moe, Elin. Crystal structure of Deinococcus radiodurans Endonuclease III-1 R61Q variant. 2022. https://www.rcsb.org/structure/8A5F.
  6. Borges, Patricia T.; Rollo, F.,; Moe, Elin. Autor correspondente: Moe, Elin. Crystal structure of Deinococcus radiodurans Endonuclease III-3 double mutant. 2022. https://www.rcsb.org/structure/8A5G.
  7. Fernandes, A.; Williamson, A.K.; Matias, P.M.; Moe, Elin. Structure of the C-terminally truncated NAD+-dependent DNA ligase from the poly-extremophile Deinococcus radiodurans. 2022. https://www.rcsb.org/structure/8AKA.
  8. Trindade, I.B.; Rollo, F.; Matias, P.M.; Moe, Elin; Louro, R.O.. Crystal Structure of E. coli FhuF. 2022. https://www.rcsb.org/structure/7QP5.
  9. Trindade, I.B.; Moe, Elin; Matias, P.M.. Optimizing electroactive organisms: the effect of orthologous proteins. 2018. https://www.rcsb.org/structure/6HR0.
  10. Trindade, I.B.; Silva, J.P.M.; Matias, P.M.; Moe, Elin. Structure and reactivity of a siderophore-interacting protein from the marine bacterium Shewanella reveals unanticipated functional versatility.. 2018. https://www.rcsb.org/structure/6GEH.
  11. Lian, K.; Leiros, H.-K.S.; Moe, Elin. Structure and function analysis of MutT from the psychrofile fish pathogen Aliivibrio salmonicida and the mesophile Vibrio cholerae. 2014. https://www.rcsb.org/structure/4V14.
  12. Pedersen, H.L.; Johnson, K.A.; Mcvey, C.E.; Leiros, I.; Moe, Elin. Crystal structure determination of uracil-DNA N-glycosylase (UNG) from Deinococcus radiodurans in complex with DNA - new insights into the role of the Leucine-loop for damage recognition and repair.. 2014. https://www.rcsb.org/structure/4UQM.
  13. Niiranen, L.; Lian, K.; Johnson, K.A.; Moe, Elin. Deinococcus radiodurans DNA polymerase III subunit beta. 2014. https://www.rcsb.org/structure/4TRT.
  14. Sarre, A.; Okvist, M.; Klar, T.; Hall, D.; Smalas, A.O.; McSweeney, S.; Timmins, J.; Moe, Elin. Crystal structure of Deinococcus radiodurans Endonuclease III-3. 2014. https://www.rcsb.org/structure/4UOB.
  15. Sarre, A.; Okvist, M.; Klar, T.; Hall, D.; Smalas, A.O.; McSweeney, S.; Timmins, J.; Moe, Elin. Crystal structure of Deinococcus radiodurans Endonuclease III-1. 2014. https://www.rcsb.org/structure/4UNF.
  16. Assefa, N.G.; Niiranen, L.M.K.; Johnson, K.A.; Leiros, H.-K.S.; Smalas, A.O.; Willassen, N.P.; Moe, Elin. Crystal structure of uracil-DNA glycosylase from cod (Gadus morhua) in complex with the proteinaceous inhibitor UGI. 2013. https://www.rcsb.org/structure/4LYL.
  17. Assefa, N.G.; Niiranen, L; Willassen, N.P.; Smalas, A.O.; Moe, Elin. Crystal structure of human uracil-DNA glycosylase D183G/K302R mutant. 2011. https://www.rcsb.org/structure/3TKB.
  18. Moe, Elin; Hall, D.R.; Leiros, I.; Talstad, V.; Timmins, J.; McSweeney, S.. Structure of an unusual 3-Methyladenine DNA Glycosylase II (Alka) from Deinococcus radiodurans. 2011. https://www.rcsb.org/structure/2YG8.
  19. Leiros, H.-K.S.; Pey, A.L.; Innselset, M.; Moe, Elin; Leiros, I.; Steen, I.H.; Martinez, A.. Structure of the cold active phenylalanine hydroxylase from Colwellia psychrerythraea 34H. 2007. https://www.rcsb.org/structure/2V27.
  20. Altermark, B.; Helland, R.; Moe, Elin; Willassen, N.P.; Smalas, A.O.. Structural adaptation of endonuclease I from the cold-adapted and halophilic bacterium Vibrio salmonicida. 2007. https://www.rcsb.org/structure/2PU3.
  21. Raeder, I.L.U.; Moe, Elin; Willassen, N.P.; Smalas, A.O.; Leiros, I.. Crystal structure of Uracil DNA-glycosylase from Vibrio cholerae. 2007. https://www.rcsb.org/structure/2JHQ.
  22. Leiros, I.; Nabong, M.P.; Grosvik, K.; Ringvoll, J.; Haugland, G.T.; Uldal, L.; Reite, K.; et al. 3-methyladenine dna-glycosylase from Archaeoglobus fulgidus. 2007. https://www.rcsb.org/structure/2JHJ.
  23. Dennis, R.,; Micossi, E.; McCarthy, J.; Moe, Elin; Gordon, E.; Leonard, G.; McSweeney, S.. Manganese Superoxide Dismutase (Mn-SOD) from Deinococcus radiodurans. 2006. https://www.rcsb.org/structure/2CDY.
  24. Moe, Elin; Leiros, I.; Smalas, A.O.; McSweeney, S.. The crystal structure of mismatch specific uracil-DNA glycosylase (MUG) from Deinococcus radiodurans. 2005. https://www.rcsb.org/structure/2C2P.
  25. Leiros, I.; Moe, Elin; Smalas, A.O.; McSweeney, S.. The crystal structure of Uracil-DNA N-Glycosylase (UNG) from Deinococcus radiodurans.. 2005. https://www.rcsb.org/structure/2BOO.
  26. Moe, Elin; Leiros, I.; Riise, E.K.; Olufsen, M.; Lanes, O.; Smalas, A.O.; Willassen, N.P.. Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA N-glycosylase (UNG)from atlantic cod (Gadus morhua). 2005. https://www.rcsb.org/structure/1YUO.
  27. Leiros, I.; Moe, Elin; Lanes, O.; Smalas, A.O.; Willassen, N.P.. crystal structure of Uracil-DNA glycosylase from Atlantic cod (Gadus morhua). 2003. https://www.rcsb.org/structure/1OKB.
Resumo em conferência
  1. Frade, K.; Fernandes, A.; Silveira, C.M.; Frazao, C.; Todorovic, S.; Moe, Elin. "Biophysical and crystallization analysis of a novel peroxidase from Deinococcus radiodurans". Trabalho apresentado em The 19th SFRRI Biennial Meeting, Lisbon, 2018.
    Publicado • https://doi.org/10.1016/j.freeradbiomed.2018.04.379
  2. Rolli, F.; Silveira, C.M.; Timmins, J.; Todorovic, S.; Moe, Elin. "Structure/function analysis of two mutated Endonuclease III enzymes from the extremophile Deinococcus radiodurans". Trabalho apresentado em The 19th SFRRI Biennial Meeting, Lisbon, 2018.
    Publicado • https://doi.org/10.1016/j.freeradbiomed.2018.04.372
Tese / Dissertação
  1. Moe, Elin. "The molecular basis for cold adaptation of uracil-DNA N-glycosylase from Atlantic cod (Gadus morhua)". Doutoramento, University of Tromsø - The Arctic University of Norway, 2002.
  2. Moe, Elin. "Optimisation of induced expression of human parathyroide hormone (hPTH) in Saccharomyces cerevisiae". Mestrado, University of Oslo, 1997.
Atividades

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2024/02/23 Discovery of novel marine clostripain-like proteases from Arctic hydrothermal vents: Activation mechanism, substrate utilization and biotechnological aspects.
Arguente principal
Victoria Røyseth (Doutoramento)
Universitetet i Bergen, Noruega
2023/10/03 Unveiling the role of Polyphosphate kinase 1 in the cellular protection against oxidative stress
Arguente principal
Bruno Lopes (batchelor) (Outro)
Instituto Politécnico de Setúbal, Portugal
2022/11/15 Cold-adapted proteases Identifying and characterizing cold-adapted intracellular subtilisin proteases
Arguente principal
Casper Bøyer Rasmussen (Doutoramento)
2021/06/09 Bioprospecting for enzymes from deep sea microorganisms
Arguente
Hasan Arsin. (Doutoramento)
University of Bergen, Faculty of Mathematics and Natural Sciences, Noruega
2019 LytR inhibition, an approach to avoid biofilm formation in Streptococcus dysgalactiae. Subs dysgalactiae.
Arguente principal
João Carlos Paquete Ferreira (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018 The role of Ubiquitin Specific Protease 7 on Latency Associated Nuclear Antigen DNA binding.
Arguente principal
Gonçalo Nunes (Mestrado)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2016 Structural and functional studies on human enzymes involved in hydrogen sulfide breakdown
Arguente principal
André Gutierres (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014 Structure-function analysis of isocitrate dehydrogenase subfamily II: Adaptions to hot and cold.
Arguente
Anita-Elin Fedøy (Doutoramento)
University of Bergen, Department of Biomedicine, Noruega

Arbitragem científica em conferência

Nome da conferência Local da conferência
2021/02 - 2023/02 BIOPROSP_23 Unlocking the potential of biomolecules from marine environments UiT - the arcitic university of Norway

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2019/01/01 - Atual Course responsible: Protein production technology (KJE-3603) (Mestrado) University of Tromsø - The Arctic University of Norway - Department of Chemistry, Noruega
2014 - 2018 Lecturer: Protein production technology (Kje-3603), UiT, Norway Protein production technology (Mestrado) University of Tromsø - The Arctic University of Norway - Department of Chemistry, Noruega
2007 - 2007 Lecturer: Introduction to protein structures (BT8115), NTNU, Norway. Introduction to protein structures (Mestrado) The Norwegian University of Science and Technology (NTNU), Noruega
1998 - 2000 Laboratory teacher: Methods in biotechnology (Mestrado integrado) University of Tromsø - The Arcitic University of Norway - Department of Medical Biology, Noruega
1999 - 1999 Laboratory teacher: Fermentation (Mestrado integrado) University of Tromsø - The Arcitic University of Norway - Department of Medical Biology, Noruega
1996 - 1996 Laboratory assistant: Laboratory course in biochemistry (Mestrado) University of Oslo - Division of Biochemistry, Noruega

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2023/02/09 Interview regarding Innovation price for project: From trash to Treasure. Oeiras Valley Portal
2022/05/23 Publication of the winners of InnOvalley prices from the Municipality of Oeiras Publico
2022/05/20 Presentation of winners of InnOvalley price from Oeiras municipality Expresso

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2023/02 - Atual Member of the board of the Post Doctorate Association (PdA) ITQB NOVA
Coordenador
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2007 - 2011 Member of the local board of the Norwegian Biochemical Society (NBS) at UiT - the arctic university of Norway.
Membro
Distinções

Prémio

2022 PoC Fund Award for project "From Trash to Treasure - developing proprietary collagenases for transformation of fish waste into high value products".
ITQB NOVA and Camera Municipal Oeiras, Portugal
2022 Prémio Investigação Científica em Ciências Militares 2022
Governo da Republica Portuguesa Ministério da Defesa Nacional, Portugal

Estado-Maior-General das Forças Armadas, Portugal

Instituto Universitário Militar, Portugal