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Mariana Marques (MM, SC: 57204763388, 13 papers, H-index: 4) is a young clinical pathologist researcher whose plasma analytic profiling and metabolic interpretation will be of great value. Moreover, her entrepreneurship spirit and straight connection with medical spin-off companies will be crucial to search for partners interested in the potential patent of FGF21 novel applications, an output expected for FIT-HEART. Her main research interests focus on cardiovascular disease biomarkers and clinical outcomes, including work in aortic stenosis, atrial fibrillation and carotid stenosis. Translational and clinical research methodology, including study design and statistical analysis represent core research skills. She is a Physiology instructor at the Faculty of Medicine of the University of Porto and a Clinical Pathologist at São João University Hospital Center.
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Identificação

Identificação pessoal

Nome completo
Mariana Fragão-Marques

Nomes de citação

  • Fragão-Marques, Mariana

Identificadores de autor

Ciência ID
C41A-D112-1EA7
ORCID iD
0000-0003-1236-0233

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Formação
Grau Classificação
2017/09 - 2023/01
Concluído
 Doutoramento em Ciências Cardiovasculares (Doutoramento)
Universidade do Porto, Portugal
2020/02/15 - 2022/02/15
Concluído
 Clinical Scholars Research Training Program (Pós-Graduação)
Especialização em Clinical Research and Epidemiology
Harvard Medical School, Estados Unidos
2020/10 - 2022/02
Concluído
 Digital Master of Business and Administration (Mestrado)
Universidade do Porto Porto Business School, Portugal
2017
Concluído
 Medical Doctor (Mestrado integrado)
Universidade do Porto Faculdade de Medicina, Portugal
"Risk factors predictive of postoperative atrial fibrillation" (TESE/DISSERTAÇÃO)
 16
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2018 - Atual Assistente Convidado (Docente Universitário) Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal

Outras Carreiras

Categoria Profissional
Instituição de acolhimento 		Empregador
2023/09 - Atual Carreiras / Categorias Subsistentes Novo Nordisk A/S Søborg R&D Centre, Dinamarca
2018/01/01 - 2023 Interno (Médica) Centro Hospitalar Universitário de São João, Portugal
Centro Hospitalar Universitário de São João, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2016 - Atual Researcher Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
Produções

Publicações

Artigo em revista
  1. Mariana Fragão-Marques; Vitorino, R.; Isaac Barroso; Inês Falcão-Pires; Adelino Leite-Moreira; Fábio Trindade. "Pericardial Fluid Annexin A1 Is a Marker of Atrial Fibrillation in Aortic Stenosis: A Proteomics Analysis". Journal of Personalized Medicine (2022): https://www.mdpi.com/2075-4426/12/2/264.
    10.3390/jpm12020264
  2. Mancio, Jennifer; Sousa-Nunes, Fabio; Martins, Rafael; Fragao-Marques, Mariana; Conceicao, Gloria; Pessoa-Amorim, Guilherme; Barros, Antonio S.; et al. "Decoding the radiomic and proteomic phenotype of epicardial adipose tissue associated with adverse left atrial remodelling and post-operative atrial fibrillation in aortic stenosis". European Heart Journal - Cardiovascular Imaging (2022): https://publons.com/wos-op/publon/52722196/.
    10.1093/EHJCI/JEAC092
  3. Pereira-Neves, Antonio; Saramago, Sean; Duarte-Gamas, Luis; Domingues-Monteiro, Diogo; Fragao-Marques, Mariana; Marques-Vieira, Mario; Andrade, Jose P.; Pais, Sandra; Rocha-Neves, Joao. "Mean Platelet Volume Predicts Restenosis After Carotid Endarterectomy". Annals of Vascular Surgery (2022): https://publons.com/wos-op/publon/50068041/.
    10.1016/J.AVSG.2021.08.054
  4. Garcia, Teresa; Fragao-Marques, Mariana; Pimentao, Pedro; Pinto, Martim; Pedro, Ines; Martins, Carlos. "Tranexamic acid in total shoulder arthroplasty under regional anesthesia: a randomized, single blinded, controlled trial". Brazilian Journal of Anesthesiology (2022): https://publons.com/wos-op/publon/28042473/.
    10.1016/J.BJANE.2021.02.011
  5. Mariana Fragão-Marques; Isaac Barroso; Rui Farinha; Isabel M Miranda; Diana Martins; Jennifer Mancio; João Rocha-Neves; et al. "Pericardial NT-Pro-BNP and GDF-15 as Biomarkers of Atrial Fibrillation and Atrial Matrix Remodeling in Aortic Stenosis". Diagnostics (2021): https://www.mdpi.com/2075-4418/11/8/1422.
    10.3390/diagnostics11081422
  6. Fragão-Marques, Mariana. "Red blood cell distribution width is associated with hypoperfusion in carotid endarterectomy under regional anesthesia.". Surgery (2021): https://doi.org/10.1016/j.surg.2021.01.004.
    10.1016/j.surg.2021.01.004
  7. "12th National Scientific Congress SPML,29–31 October 2020, Online, Portugal". Clinical Chemistry and Laboratory Medicine (2021): https://publons.com/publon/51413546/.
    10.1515/CCLM-2021-0360
  8. Machado, I.; Teixeira, S.; Goncalves, D.; Carvalho, M.; Fragao-Marques, M.; Neves, C.; Lopes, M.; Fernandes, S.; Koch, C.. "VON WILLEBRAND DISEASE TYPE 2B AND DDAVP. STILL A TREATMENT DRUG TO AVOID?". Haematologica (2021): https://publons.com/publon/51397808/.
  9. Fragao-Marques, Mariana; Teixeira, Francisco; Mancio, Jennifer; Seixas, Nair; Rocha-Neves, Joao; Falcao-Pires, Ines; Leite-Moreira, Adelino. "Impact of oral anticoagulation therapy on postoperative atrial fibrillation outcomes: a systematic review and meta-analysis". Thrombosis Journal (2021): https://publons.com/wos-op/publon/48485913/.
    10.1186/S12959-021-00342-2
  10. Fragao-Marques, Mariana; Barroso, Isaac; Loureiro, Hugo; Duarte-Gamas, Luis; Pinheiro, Dolores; Guimaraes, Joao T.. "Inflammatory Response Assessment in Patients with COVID-19 Under Extracorporeal Membrane Oxygenation Support". Clinical Laboratory (2021): https://publons.com/wos-op/publon/46820266/.
    10.7754/CLIN.LAB.2020.200916
  11. Fragão-Marques, Mariana. "Red Blood Cell Distribution Width as a 5-Year Prognostic Marker in Patients Submitted to Carotid Endarterectomy.". Cerebrovascular diseases extra (2020): https://europepmc.org/articles/PMC7841742.
    10.1159/000512587
  12. Fragão-Marques, Mariana. "Influence of EPICardial adipose tissue in HEART diseases (EPICHEART) study: Protocol for a translational study in coronary atherosclerosis.". Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology (2020): https://doi.org/10.1016/j.repc.2020.03.017.
    10.1016/j.repc.2020.03.017
  13. Fragão-Marques, Mariana. "Atrial matrix remodeling in atrial fibrillation patients with aortic stenosis.". BMC cardiovascular disorders (2020): https://europepmc.org/articles/PMC7603735.
    10.1186/s12872-020-01754-0
  14. Fragão-Marques, Mariana. "Adverse remodeling in atrial fibrillation following isolated aortic valve replacement surgery.". Perfusion (2020): https://doi.org/10.1177/0267659120949210.
    10.1177/0267659120949210
  15. Fragão-Marques, Mariana. "Gender Differences in Predictors and Long-Term Mortality of New-Onset Postoperative Atrial Fibrillation Following Isolated Aortic Valve Replacement Surgery.". Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia (2020): https://europepmc.org/articles/PMC7801179.
    10.5761/atcs.oa.19-00314
  16. "11th National Scientifc Congress SPML". Clinical Chemistry and Laboratory Medicine (2019): https://publons.com/publon/51413398/.
    10.1515/CCLM-2019-1173
  17. Fragao-Marques, M.; Trindade, F.; Vitorino, R.; Falcao-Pires, I.; Leite-Moreira, A.. "Uncovering new surrogate markers for atrial fibrillation through pericardial fluid proteomics". Clinica Chimica Acta (2019): https://publons.com/wos-op/publon/37638285/.
    10.1016/J.CCA.2019.03.369
  18. Fragão-Marques, Mariana. "Meta-Analysis of Relation of Epicardial Adipose Tissue Volume to Left Atrial Dilation and to Left Ventricular Hypertrophy and Functions.". The American journal of cardiology (2018): https://doi.org/10.1016/j.amjcard.2018.10.020.
    10.1016/j.amjcard.2018.10.020
  19. Fragão-Marques, Mariana. "De novo atrial fibrillation following aortic valve replacement surgery is associated with decreased creatinine clearance and increased C-reactive protein levels: PS025.". Porto biomedical journal (2017): https://europepmc.org/articles/PMC6806850.
    10.1016/j.pbj.2017.07.034
  20. Fragão-Marques, Mariana. "[De novo atrial fibrillation following aortic valve replacement surgery].". Revista portuguesa de cirurgia cardio-toracica e vascular : orgao oficial da Sociedade Portuguesa de Cirurgia Cardio-Toracica e Vascular (2016):
  21. Francisco Vasques-Nóvoa; Catarina Quina-Rodrigues; Rui Cerqueira; Fabiana Baganha; Mariana I Marques; Adelino F Leite-Moreira; Roberto Roncon-Albuquerque. "Abstract 20517: MicroRNA-155: A New Player in Sepsis-Induced Cardiac Dysfunction". Circulation (2014): https://publons.com/publon/52004089/.
    10.1161/CIRC.130.SUPPL_2.20517
Distinções

Prémio

2021 InovPed 2021
2021 Award Angelini Shark Tank 2021
Sociedade Portuguesa de Cirurgia Cardíaca, Torácica e Vascular, Portugal

Outra distinção

2017 Award for best paralel oral session in Surgery
2015 Award for best poster presentation in Cardiology