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Prof. Van Dijck studied biology at KU Leuven. After one postgraduate year in Biotechnology, he started his PhD in the Laboratory of Experimental Endocrinology on steroid-hormone regulated gene expression. After a five-year postdoc in the Laboratory of Molecular Cell Biology, in the lab of Prof. Thevelein, Department of Biology, working on yeast biotechnology, he went to Janssen Pharmaceutica (J&J) to introduce molecular biology work in the Department of Biochemistry, with a focus on the development of high-throughput drug screening for baculovirus produced enzymes and gene expression interference. After 2 and half years, in 1997, he came back to the MCB lab as an independent PI of the Flemish Institute for Biotechnology, VIB. The focus was then on plant trehalose metabolism as well as starting the work on the human fungal pathogen Candida albicans. In 2003 he became associate research professor and full professor in 2013. In his research group there are currently three main research lines. The first focus is on nutrient-induced signal transduction pathways that affect morphogenesis and virulence in Candida species. There are also ongoing activities to identify novel antifungal compounds from either plant essential oils or from soil microbiota fermentation products. The third research topic is on the elucidation of antifungal resistance and tolerance mechanisms with a focus on the emerging human fungal pathogen Candida auris. Prof. Van Dijck published 242 peer reviewed papers and has an H-index in google scholar of 75.
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Identificação

Identificação pessoal

Nome completo
Van Dijck Patrick

Nomes de citação

  • Van Dijck, P

Identificadores de autor

Ciência ID
CB17-DFBC-E679
ORCID iD
0000-0002-1542-897X

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Ciências da Saúde - Doenças Infeciosas

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Holandês (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador independente (B1) Utilizador independente (B2) Utilizador elementar (A2) Utilizador independente (B1) Utilizador elementar (A2)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1)
Formação
Grau Classificação
1985/10/01 - 1991/11/13
Concluído
 Patrick Van Dijck (Doktor (PhD))
Especialização em Molecular Endocrinology
Associatie KU Leuven, Bélgica
"Structural and functional study of the 5'-upstream region of three members of the *2u-globulin gene family in the rat. A comparative study of their interaction with steroid receptors and other nuclear factors" (TESE/DISSERTAÇÃO)
1984/10/01 - 1985/07/12
Concluído
 Patrick Van Dijck (Postgraduate Certificate)
Especialização em Certificate in Biotechnology, medical and biochemical orientation
Associatie KU Leuven, Bélgica
1982/10/01 - 1984/07/10
Concluído
 Patrick Van Dijck (Master Universitario)
Especialização em Physiology and Biochemistry
Associatie KU Leuven, Bélgica
"Ecologische studie van een moerasvegetatie in de Demervallei: kompetitie, zaakbankanalyse en zaakkieming" (TESE/DISSERTAÇÃO)
1980/10/01 - 1982/09/15
Concluído
 Patrick Van Dijck (Bachelor)
Associatie KU Leuven, Bélgica
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
1997/07/01 - 2021/12/31 Investigador principal (carreira) (Investigação) Vlaams Instituut voor Biotechnologie VIB-KU Leuven Center for Microbiology, Bélgica

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2003/10/01 - Atual Professor Catedrático (Docente Universitário) Katholieke Universiteit Leuven, Bélgica
Projetos

Bolsa

Designação Financiadores
2025/08/01 - 2028/07/31 Dissection of sphingolipid-ergosterol interactions to combat polyene resistance in infectious Candida
0095912
Co-Investigador Responsável (Co-IR)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
 Københavns Universitet Novo Nordisk Fondens Center for Grundlæggende Metabolisk Forskning
Em curso
2023/10/01 - 2027/09/30 DeVEnIR: defining vulvovaginal candidiasis - elements of infection and remedy
S006424N
Investigador responsável
Laboratory of Molecular Cell Biology, Bélgica
 Fonds Wetenschappelijk Onderzoek Vlaanderen
Em curso
2022/10/01 - 2026/09/30 Investigation of the molecular mechanism by which iron availability in the mitochondria affect tolerance towards the anti fungal drug fluconazole in the human fungal pathogen Candida albicans
C14/22/075
Investigador responsável
Em curso
2023/01/01 - 2025/12/31 Disrupting drug resistance by exploiting collateral sensitivity to design novel therapeutic strategies for C. auris and C. glabrata infections (CycleDrug).
G0L1622N
Investigador responsável
Em curso
2022/01/01 - 2025/12/31 Investigation of the underlying mechanism by which the PKA and calcineurin pathway regulate stress tolerance in the human fungal pathogen Candida glabrata
G0C0622N
Investigador responsável
Associatie KU Leuven, Bélgica
 Fonds Wetenschappelijk Onderzoek Vlaanderen
Em curso
2022/10/01 - 2025/09/30 Optimization and validation of collateral sensitivity based alternative treatment strategies for multidrug resistant Candidemia
C3/22/007
Investigador responsável
Em curso
2021/10/01 - 2025/09/30 FWO research community: Biology and ecology of bacterial and fungal biofilms in humans
W000921N
Investigador responsável
Fonds Wetenschappelijk Onderzoek Vlaanderen, Bélgica
Em curso
2023/01/01 - 2024/12/31 Yeast cell surface display of PET-hydrolyzing enzymes to degrade PET and pretreat PET-containing organic side streams prior to black soldier fly larvae rearing (PETyFLY)
G0D9723N
Investigador responsável
Fonds Wetenschappelijk Onderzoek Vlaanderen, Bélgica
2022/01/01 - 2023/12/31 Synthesis and transformation of muconic acid into platform molecules starting from biomass (MUCOFORM)
G0G2622N
Investigador responsável
Associatie KU Leuven, Bélgica
 Fonds Wetenschappelijk Onderzoek Vlaanderen
2020/01/01 - 2023/12/31 Investigation towards the importance for virulence and biofilm formation of a novel pathway for glycerol biosynthesis in the human fungal pathogen Candida albicans
G0B1820N
Investigador responsável
Associatie KU Leuven, Bélgica
 Fonds Wetenschappelijk Onderzoek Vlaanderen
Em curso
2020/10/01 - 2022/09/30 Purification, characterisation and valorisation of novel antifungal compounds secreted by soil microorganisms
C3/20/008
Investigador responsável
Associatie KU Leuven, Bélgica
 Katholieke Universiteit Leuven Onderzoeksraad
Em curso
2019/01/01 - 2021/12/31 G-protein-coupled receptors (GPCRs) of human pathogenic fungi and their role on growth, morphogenesis and virulence
G0F8519N
Investigador responsável
Associatie KU Leuven, Bélgica
 Fonds Wetenschappelijk Onderzoek Vlaanderen
Concluído
2017/10/01 - 2021/09/30 Deciphering the network that links nutrient signaling in yeast with growth potential, pH and Ca2+ homeostasis, ageing and lifespan, resistance and virulence
C14/17/063
Investigador responsável
Associatie KU Leuven, Bélgica
 Katholieke Universiteit Leuven Onderzoeksraad
Concluído
2017/10/01 - 2021/09/30 C. albicans and S. aureus catheter infections: clinical implications and therapy
R01AI130170 (NIAID)
Investigador responsável
Foundation for the National Institutes of Health
Concluído
2019/03/15 - 2021/03/14 Postharvest protection of fruit using a natural formulation printed on stickers.
HBC.2019.2143
Investigador responsável
Vlaanderen Agentschap Innoveren & Ondernemen
Concluído
2017/04/01 - 2020/03/31 Stimulating antifungal innate immunity
G0H7816N
Investigador responsável
Associatie KU Leuven, Bélgica
 Fonds Wetenschappelijk Onderzoek Vlaanderen
Concluído

Projeto

Designação Financiadores
2023/11/01 - 2025/05/31 MetaFungal-Metabolism of carboxylic acids in Fungal Infections
PTDC/BIA-MIC/5246/2020
10.54499/PTDC/BIA-MIC/5246/2020
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal

Universidade do Minho Escola de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/08/17 - 2021/12/31 Development of yeast-based biosensors for the detection of cannabinoid compounds.
no number
Investigador responsável
Concluído
2021/01/01 - 2021/06/30 Validation of antifungal activity of probiotic bacteria
no number
Investigador responsável
PROBIBEL
Concluído
Produções

Publicações

Artigo em revista
  1. Qingjuan Zhu; Stefanie Wijnants; Regina Feil; Wouter Van Genechten; Rudy Vergauwen; Odessa Van Goethem; John E. Lunn; et al. "The stress-protectant molecule trehalose mediates fluconazole tolerance in Candida glabrata". Antimicrobial Agents and Chemotherapy (2025): https://doi.org/10.1128/aac.01349-24.
    10.1128/aac.01349-24
  2. Andreas Biront; Mart Sillen; Patrick Van Dijck; Jan Wurm. "Growth Propagation of Liquid Spawn on Non-Woven Hemp Mats to Inform Digital Biofabrication of Mycelium-Based Composites". Biomimetics (2025): https://doi.org/10.3390/biomimetics10010033.
    10.3390/biomimetics10010033
  3. Stef Jacobs; Giorgio Boccarella; Pieter van den Berg; Patrick Van Dijck; Hans Carolus. "Unlocking the potential of experimental evolution to study drug resistance in pathogenic fungi". npj Antimicrobials and Resistance (2024): https://doi.org/10.1038/s44259-024-00064-1.
    10.1038/s44259-024-00064-1
  4. Carolus, Hans; Sofras, Dimitrios; Boccarella, Giorgio; Sephton-Clark, Poppy; Biriukov, Vladislav; Cauldron, Nicholas C.; Lobo Romero, Celia; et al. "Acquired amphotericin B resistance leads to fitness trade-offs that can be mitigated by compensatory evolution in Candida auris". Nature Microbiology 9 12 (2024): 3304-3320. https://doi.org/10.1038/s41564-024-01854-z.
    10.1038/s41564-024-01854-z
  5. Jana Nysten; Arne Peetermans; Dries Vaneynde; Stef Jacobs; Liesbeth Demuyser; Patrick Van Dijck; Joseph Heitman. "The riboflavin biosynthetic pathway as a novel target for antifungal drugs against Candida species". mBio (2024): https://doi.org/10.1128/mbio.02502-24.
    10.1128/mbio.02502-24
  6. Basharat Ali; Anshu Chauhan; Mohit Kumar; Praveen Kumar; Hans Carolus; Celia Lobo Romero; Rudy Vergauwen; et al. "A Comprehensive Analysis of the Lipidomic Signatures in Rhizopus delemar". Journal of Fungi (2024): https://www.mdpi.com/2309-608X/10/11/760.
    10.3390/jof10110760
  7. Carolus, Hans; Sofras, Dimitrios; Boccarella, Giorgio; Jacobs, Stef; Biriukov, Vladislav; Goossens, Louise; Chen, Alicia; et al. "Collateral sensitivity counteracts the evolution of antifungal drug resistance in Candida auris". Nature Microbiology 9 11 (2024): 2954-2969. https://doi.org/10.1038/s41564-024-01811-w.
    10.1038/s41564-024-01811-w
  8. Tristan W. Wang; Dimitrios Sofras; Daniel Montelongo-Jauregui; Telmo O. Paiva; Hans Carolus; Yves F. Dufrêne; Areej A. Alfaifi; et al. "Functional redundancy in Candida auris cell surface adhesins crucial for cell-cell interaction and aggregation". Nature Communications (2024): https://doi.org/10.1038/s41467-024-53588-5.
    10.1038/s41467-024-53588-5
  9. Sinah Tönjes; Evelien Uitterhaegen; Ilse Palmans; Birthe Ibach; Karel De Winter; Patrick Van Dijck; Wim Soetaert; Paul Vandecruys. "Metabolic Engineering and Process Intensification for Muconic Acid Production Using Saccharomyces cerevisiae". International Journal of Molecular Sciences (2024): https://doi.org/10.3390/ijms251910245.
    10.3390/ijms251910245
  10. Chinmayee Awasthy; Zeinab Abdelmoghis Hefny; Wouter Van Genechten; Uwe Himmelreich; Patrick Van Dijck; Erik F.Y. Hom. "Involvement of 2-deoxyglucose-6-phosphate phosphatases in facilitating resilience against ionic and osmotic stress in Saccharomyces cerevisiae". Microbiology Spectrum (2024): https://doi.org/10.1128/spectrum.00136-24.
    10.1128/spectrum.00136-24
  11. Jonas Devos; Patrick Van Dijck; Wouter Van Genechten. "A multi-colour fluorogenic tag and its application in Candida albicans". Microbiology (2024): https://doi.org/10.1099/mic.0.001451.
    10.1099/mic.0.001451
  12. Jana Nysten; Mary Ann Jabra-Rizk; Dimitrios Sofras; Patrick Van Dijck. "One species, many faces: The underappreciated importance of strain diversity". PLOS Pathogens (2024): https://doi.org/10.1371/journal.ppat.1011931.
    10.1371/journal.ppat.1011931
  13. Wouter Van Genechten; Rudy Vergauwen; Patrick Van Dijck. "The intricate link between iron, mitochondria and azoles in Candida species". The FEBS Journal (2023): https://doi.org/10.1111/febs.16977.
    10.1111/febs.16977
  14. Paul Vandecruys; Silke Baldewijns; Mart Sillen; Wouter Van Genechten; Patrick Van Dijck. "Oteseconazole: a long-awaited diversification of the antifungal arsenal to manage recurrent vulvovaginal candidiasis (RVVC)". Expert Review of Anti-infective Therapy (2023): https://doi.org/10.1080/14787210.2023.2233696.
    10.1080/14787210.2023.2233696
  15. Jana Nysten; Jorn Coers; Patrick Van Dijck. "Can we microbe-manage our vitamin acquisition for better health?". PLOS Pathogens (2023): https://doi.org/10.1371/journal.ppat.1011361.
    10.1371/journal.ppat.1011361
  16. Stefanie Wijnants; Jolien Vreys; Jana Nysten; Patrick Van Dijck. "The Cdc25 and Ras1 Proteins of Candida albicans Influence Epithelial Toxicity in a Niche-Specific Way". Journal of Fungi (2023): https://doi.org/10.3390/jof9020201.
    10.3390/jof9020201
  17. Giel Vanreppelen; Jurgen Wuyts; Patrick Van Dijck; Paul Vandecruys. "Sources of Antifungal Drugs". Journal of Fungi (2023): https://doi.org/10.3390/jof9020171.
    10.3390/jof9020171
  18. Giel Vanreppelen; Jana Nysten; Silke Baldewijns; Mart Sillen; Gilbert Donders; Patrick Van Dijck. "Oteseconazole (VIVOJA) for prevention of recurrent vulvovaginal candidiasis". Trends in Pharmacological Sciences (2023): https://doi.org/10.1016/j.tips.2022.10.004.
    10.1016/j.tips.2022.10.004
  19. Rita M. Pinto; Catarina Leal Seabra; Martine De Jonge; M. Cristina L. Martins; Patrick Van Dijck; Salette Reis; Cláudia Nunes. "Antibiofilm Combinatory Strategy: Moxifloxacin-Loaded Nanosystems and Encapsulated N-Acetyl-L-Cysteine". Pharmaceutics (2022): https://doi.org/10.3390/pharmaceutics14112294.
    10.3390/pharmaceutics14112294
  20. Wissal Chebil; Najoua Haouas; Elja Eskes; Paul Vandecruys; Sameh Belgacem; Hichem Belhadj Ali; Hamouda Babba; Patrick Van Dijck. "In Vitro Assessment of Azole and Amphotericin B Susceptibilities of Malassezia spp. Isolated from Healthy and Lesioned Skin". Journal of Fungi (2022): https://doi.org/10.3390/jof8090959.
    10.3390/jof8090959
  21. Meng Zhang; Guangxin Huo; Juncheng Bao; Tomislav Markovic; Patrick Van Dijck; Bart Nauwelaers. "Microwave Interferometric Cytometry for Signal Analysis of Single Yeast Cells". Chemosensors (2022): https://doi.org/10.3390/chemosensors10080318.
    10.3390/chemosensors10080318
  22. Tran Le Cong Huyen Bao Phan; Nathalie Crepin; Filip Rolland; Patrick Van Dijck. "Two trehalase isoforms, produced from a single transcript, regulate drought stress tolerance in Arabidopsis thaliana". Plant Molecular Biology (2022): https://doi.org/10.1007/s11103-022-01243-2.
    10.1007/s11103-022-01243-2
  23. Stefanie Wijnants; Jolien Vreys; Patrick Van Dijck. "Interesting antifungal drug targets in the central metabolism of Candida albicans". Trends in Pharmacological Sciences (2022): https://doi.org/10.1016/j.tips.2021.10.003.
    10.1016/j.tips.2021.10.003
  24. Nicolas Papon; Patrick Van Dijck. "A Complex Microbial Interplay Underlies Recurrent Vulvovaginal Candidiasis Pathobiology". mSystems (2021): https://doi.org/10.1128/mSystems.01066-21.
    10.1128/mSystems.01066-21
  25. Hans Carolus; Stef Jacobs; Celia Lobo Romero; Quinten Deparis; Christina A. Cuomo; Jacques F. Meis; Patrick Van Dijck. "Diagnostic Allele-Specific PCR for the Identification of Candida auris Clades". Journal of Fungi 7 9 (2021): 754-754. https://doi.org/10.3390/jof7090754.
    10.3390/jof7090754
  26. Wouter Van Genechten; Patrick Van Dijck; Liesbeth Demuyser. "Fluorescent toys ‘n’ tools lighting the way in fungal research". FEMS Microbiology Reviews (2021): https://doi.org/10.1093/femsre/fuab013.
    10.1093/femsre/fuab013
  27. Katrien Van Dyck; Eliane Vanhoffelen; Jonas Yserbyt; Patrick Van Dijck; Marco Erreni; Sophie Hernot; Greetje Vande Velde. "Probe-based intravital microscopy: filling the gap between in vivo imaging and tissue sample microscopy in basic research and clinical applications". Journal of Physics: Photonics 3 3 (2021): 032003-032003. https://doi.org/10.1088/2515-7647/ac0804.
    10.1088/2515-7647/ac0804
  28. Purity N. Kipanga; Liesbeth Demuyser; Johannes Vrijdag; Elja Eskes; Petra D’hooge; Josphat Matasyoh; Geert Callewaert; et al. "Investigating the Antifungal Mechanism of Action of Polygodial by Phenotypic Screening in Saccharomyces cerevisiae". International Journal of Molecular Sciences (2021): https://doi.org/10.3390/ijms22115756.
    10.3390/ijms22115756
  29. Wouter Van Genechten; Liesbeth Demuyser; Sam Duwé; Wim Vandenberg; Patrick Van Dijck; Peter Dedecker; Aaron P. Mitchell. "Photochromic Fluorophores Enable Imaging of Lowly Expressed Proteins in the Autofluorescent Fungus Candida albicans". mSphere 6 2 (2021): https://doi.org/10.1128/mSphere.00146-21.
    10.1128/mSphere.00146-21
  30. Hans Carolus; Siebe Pierson; José F. Muñoz; Ana Subotic; Rita B. Cruz; Christina A. Cuomo; Patrick Van Dijck; Anuradha Chowdhary. "Genome-Wide Analysis of Experimentally Evolved Candida auris Reveals Multiple Novel Mechanisms of Multidrug Resistance". mBio 12 2 (2021): https://doi.org/10.1128/mBio.03333-20.
    10.1128/mBio.03333-20
  31. Katrien Van Dyck; Rita M. Pinto; Durgasruthi Pully; Patrick Van Dijck. "Microbial Interkingdom Biofilms and the Quest for Novel Therapeutic Strategies". Microorganisms 9 2 (2021): 412-412. https://doi.org/10.3390/microorganisms9020412.
    10.3390/microorganisms9020412
  32. Xiaoting Zheng; Adam F. Feyaerts; Patrick Van Dijck; Peter Bossier. "Inhibitory Activity of Essential Oils against Vibrio campbellii and Vibrio parahaemolyticus". Microorganisms 8 12 (2020): 1946-1946. https://doi.org/10.3390/microorganisms8121946.
    10.3390/microorganisms8121946
  33. Rosana Alves; Stavroula L. Kastora; Alexandra Gomes-Gonçalves; Nuno Azevedo; Célia F. Rodrigues; Sónia Silva; Liesbeth Demuyser; et al. "Transcriptional responses of Candida glabrata biofilm cells to fluconazole are modulated by the carbon source". npj Biofilms and Microbiomes (2020): https://doi.org/10.1038/s41522-020-0114-5.
    10.1038/s41522-020-0114-5
  34. Wouter Van Genechten; Liesbeth Demuyser; Peter Dedecker; Patrick Van Dijck. "Presenting a codon-optimized palette of fluorescent proteins for use in Candida albicans". Scientific Reports (2020): https://doi.org/10.1038/s41598-020-63308-w.
    10.1038/s41598-020-63308-w
  35. Hans Carolus; Siebe Pierson; Katrien Lagrou; Patrick Van Dijck. "Amphotericin B and Other Polyenes—Discovery, Clinical Use, Mode of Action and Drug Resistance". Journal of Fungi 6 4 (2020): 321-321. https://doi.org/10.3390/jof6040321.
    10.3390/jof6040321
  36. Liesbeth Demuyser; Ilse Palmans; Paul Vandecruys; Patrick Van Dijck; Aaron P. Mitchell. "Molecular Elucidation of Riboflavin Production and Regulation in Candida albicans, toward a Novel Antifungal Drug Target". mSphere 5 4 (2020): https://doi.org/10.1128/mSphere.00714-20.
    10.1128/mSphere.00714-20
  37. Rosana Alves; Scott G. Filler; Cláudia Barata-Antunes; Margarida Casal; Alistair J. P. Brown; Patrick Van Dijck; Sandra Paiva. "Adapting to survive: How Candida overcomes host-imposed constraints during human colonization". PLOS Pathogens (2020): https://doi.org/10.1371/journal.ppat.1008478.
    10.1371/journal.ppat.1008478
  38. Katrien Van Dyck; Mary Ann Jabra-Rizk; Ona Rogiers; Greetje Vande Velde; Patrick Van Dijck. "Let’s shine a light on fungal infections: A noninvasive imaging toolbox". PLOS Pathogens (2020): https://doi.org/10.1371/journal.ppat.1008257.
    10.1371/journal.ppat.1008257
  39. Winnie Kerstens; Anneke Kremer; Michelle Holtappels; Peter Borghgraef; Saskia Lippens; Patrick Van Dijck; Aaron P. Mitchell. "Three-Dimensional Visualization of APEX2-Tagged Erg11 in Saccharomyces cerevisiae Using Focused Ion Beam Scanning Electron Microscopy". mSphere (2020): https://doi.org/10.1128/mSphere.00981-19.
    10.1128/mSphere.00981-19
  40. Rita M Pinto; Daniela Lopes-de-Campos; M Cristina L Martins; Patrick Van Dijck; Cláudia Nunes; Salette Reis. "Impact of nanosystems in Staphylococcus aureus biofilms treatment". FEMS Microbiology Reviews (2019): https://doi.org/10.1093/femsre/fuz021.
    10.1093/femsre/fuz021
  41. Adriana Oliveira Manfiolli; Filipe Silva Siqueira; Thaila Fernanda dos Reis; Patrick Van Dijck; Sanne Schrevens; Sandra Hoefgen; Martin Föge; et al. "Mitogen-Activated Protein Kinase Cross-Talk Interaction Modulates the Production of Melanins in Aspergillus fumigatus". mBio (2019): https://doi.org/10.1128/mBio.00215-19.
    10.1128/mBio.00215-19
  42. Liesbeth Demuyser; Katrien Van Dyck; Bea Timmermans; Patrick Van Dijck. "Inhibition of Vesicular Transport Influences Fungal Susceptibility to Fluconazole". Antimicrobial Agents and Chemotherapy (2019): https://doi.org/10.1128/AAC.01998-18.
    10.1128/AAC.01998-18
  43. Ona Rogiers; Ulrika C. Frising; Sona Kucharíková; Mary Ann Jabra-Rizk; Geert van Loo; Patrick Van Dijck; Andy Wullaert; Michael Lorenz. "Candidalysin Crucially Contributes to Nlrp3 Inflammasome Activation by Candida albicans Hyphae". mBio (2019): https://doi.org/10.1128/mBio.02221-18.
    10.1128/mBio.02221-18
  44. Michelle Holtappels; Jean-Paul Noben; Patrick Van Dijck; Roland Valcke. "Fire blight host-pathogen interaction: proteome profiles of Erwinia amylovora infecting apple rootstocks". Scientific Reports 8 1 (2018): https://doi.org/10.1038/s41598-018-30064-x.
    10.1038/s41598-018-30064-x
  45. Adam F. Feyaerts; Lotte Mathé; Walter Luyten; Stijn De Graeve; Katrien Van Dyck; Lize Broekx; Patrick Van Dijck. "Essential oils and their components are a class of antifungals with potent vapour-phase-mediated anti-Candida activity". Scientific Reports 8 1 (2018): https://doi.org/10.1038/s41598-018-22395-6.
    10.1038/s41598-018-22395-6
  46. Aranka Persyn; Ona Rogiers; Matthias Brock; Greetje Vande Velde; Mohamed Lamkanfi; Ilse D. Jacobsen; Uwe Himmelreich; et al. "Monitoring of Fluconazole and Caspofungin Activity against In Vivo Candida glabrata Biofilms by Bioluminescence Imaging". Antimicrobial Agents and Chemotherapy (2018): https://doi.org/10.1128/AAC.01555-18.
    10.1128/AAC.01555-18
  47. Liesbeth Demuyser; Wouter Van Genechten; Hideaki Mizuno; Sonia Colombo; Patrick Van Dijck. "Introducing fluorescence resonance energy transfer-based biosensors for the analysis of cAMP-PKA signalling in the fungal pathogen Candida glabrata". Cellular Microbiology (2018): e12863-e12863. https://doi.org/10.1111/cmi.12863.
    10.1111/cmi.12863
  48. Jurgen Wuyts; Tom C. Hobman; Patrick Van Dijck; Michelle Holtappels. "Fungal persister cells: The basis for recalcitrant infections?". PLOS Pathogens (2018): https://doi.org/10.1371/journal.ppat.1007301.
    10.1371/journal.ppat.1007301
  49. Ona Rogiers; Michelle Holtappels; Wafi Siala; Mohamed Lamkanfi; Françoise Van Bambeke; Katrien Lagrou; Patrick Van Dijck; Sona Kucharíková. "Anidulafungin increases the antibacterial activity of tigecycline in polymicrobial Candida albicans/Staphylococcus aureus biofilms on intraperitoneally implanted foreign bodies". Journal of Antimicrobial Chemotherapy (2018): https://doi.org/10.1093/jac/dky246.
    10.1093/jac/dky246
  50. Floris Schoeters; Carol A. Munro; Christophe d’Enfert; Patrick Van Dijck; Aaron P. Mitchell. "A High-Throughput Candida albicans Two-Hybrid System". mSphere (2018): https://doi.org/10.1128/mSphere.00391-18.
    10.1128/mSphere.00391-18
  51. Greetje Vande Velde; Sona Kucharíková; Patrick Van Dijck; Uwe Himmelreich. "Bioluminescence imaging increases in vivo screening efficiency for antifungal activity against device-associated Candida albicans biofilms". International Journal of Antimicrobial Agents (2018): https://doi.org/10.1016/j.ijantimicag.2018.03.007.
    10.1016/j.ijantimicag.2018.03.007
  52. Patrick, Van. "Candida glabrata’s Genome Plasticity Confers a Unique Pattern of Expressed Cell Wall Proteins". Journal of Fungi (2018): http://www.mdpi.com/2309-608X/4/2/67.
    10.3390/jof4020067
  53. Patrick, Van. "Antifungal Activity and Synergism with Azoles of Polish Propolis". Pathogens (2018): http://www.mdpi.com/2076-0817/7/2/56.
    10.3390/pathogens7020056
  54. Sanne Schrevens; Griet Van Zeebroeck; Michael Riedelberger; Hélène Tournu; Karl Kuchler; Patrick Van Dijck. "Methionine is required for cAMP-PKA-mediated morphogenesis and virulence of Candida albicans". Molecular Microbiology (2018): https://doi.org/10.1111/mmi.13933.
    10.1111/mmi.13933
  55. Neil Andrew Brown; Sanne Schrevens; Patrick van Dijck; Gustavo Henrique Goldman. "Fungal G-protein-coupled receptors: mediators of pathogenesis and targets for disease control". Nature Microbiology 3 4 (2018): 402-414. https://doi.org/10.1038/s41564-018-0127-5.
    10.1038/s41564-018-0127-5
  56. Eric F. Kong; Christina Tsui; Sona Kucharíková; Patrick Van Dijck; Mary Ann Jabra-Rizk. "Modulation of Staphylococcus aureus Response to Antimicrobials by the Candida albicans Quorum Sensing Molecule Farnesol". Antimicrobial Agents and Chemotherapy 61 12 (2017): https://doi.org/10.1128/AAC.01573-17.
    10.1128/AAC.01573-17
  57. Michelle Holtappels; Erwin Swinnen; Lies De Groef; Jurgen Wuyts; Lieve Moons; Katrien Lagrou; Patrick Van Dijck; Sona Kucharíková. "Antifungal Activity of Oleylphosphocholine on In Vitro and In Vivo Candida albicans Biofilms". Antimicrobial Agents and Chemotherapy 62 1 (2017): https://doi.org/10.1128/AAC.01767-17.
    10.1128/AAC.01767-17
  58. Yuke Cen; Bea Timmermans; Ben Souffriau; Johan M. Thevelein; Patrick Van Dijck. "Comparison of genome engineering using the CRISPR-Cas9 system in C. glabrata wild-type and lig4 strains". Fungal Genetics and Biology 107 (2017): 44-50. https://doi.org/10.1016/j.fgb.2017.08.004.
    10.1016/j.fgb.2017.08.004
  59. Ana Subotic; Erwin Swinnen; Liesbeth Demuyser; Herlinde De Keersmaecker; Hideaki Mizuno; Hélène Tournu; Patrick Van Dijck. "A Bimolecular Fluorescence Complementation Tool for Identification of Protein-Protein Interactions in Candida albicans". G3: Genes|Genomes|Genetics 7 10 (2017): 3509-3520. https://doi.org/10.1534/g3.117.300149.
    10.1534/g3.117.300149
  60. Adam F. Feyaerts; Lotte Mathé; Walter Luyten; Hélène Tournu; Katrien Van Dyck; Lize Broekx; Patrick Van Dijck. "Assay and recommendations for the detection of vapour-phase-mediated antimicrobial activities". Flavour and Fragrance Journal (2017): https://doi.org/10.1002%2Fffj.3400.
    10.1002/ffj.3400
  61. Liesbeth Demuyser; Erwin Swinnen; Alessandro Fiori; Beatriz Herrera-Malaver; Kevin Verstrepen; Patrick Van Dijck; J. Andrew Alspaugh. "Mitochondrial Cochaperone Mge1 Is Involved in Regulating Susceptibility to Fluconazole in Saccharomyces cerevisiae and Candida Species". mBio 8 4 (2017): https://doi.org/10.1128/mBio.00201-17.
    10.1128/mBio.00201-17
  62. Susann Pohlers; Ronny Martin; Thomas Krüger; Daniela Hellwig; Frank Hänel; Olaf Kniemeyer; Hans Peter Saluz; et al. "Lipid Signaling via Pkh1/2 Regulates Fungal CO2 Sensing through the Kinase Sch9". mBio 8 1 (2017): https://doi.org/10.1128/mBio.02211-16.
    10.1128/mBio.02211-16
  63. Lucie Kraidlova; Sanne Schrevens; Hélène Tournu; Griet Van Zeebroeck; Hana Sychrova; Patrick Van Dijck; Geraldine Butler. "Characterization of the Candida albicans Amino Acid Permease Family: Gap2 Is the Only General Amino Acid Permease and Gap4 Is an S-Adenosylmethionine (SAM) Transporter Required for SAM-Induced Morphogenesis". mSphere 1 6 (2016): https://doi.org/10.1128/mSphere.00284-16.
    10.1128/mSphere.00284-16
  64. Wafi Siala; Sona Kucharíková; Annabel Braem; Jef Vleugels; Paul M Tulkens; Marie-Paule Mingeot-Leclercq; Patrick Van Dijck; Françoise Van Bambeke. "The antifungal caspofungin increases fluoroquinolone activity against Staphylococcus aureus biofilms by inhibiting N-acetylglucosamine transferase". Nature Communications 7 1 (2016): https://doi.org/10.1038/ncomms13286.
    10.1038/ncomms13286
  65. Eric F. Kong; Christina Tsui; Sona Kucharíková; David Andes; Patrick Van Dijck; Mary Ann Jabra-Rizk. "Commensal Protection of Staphylococcus aureus against Antimicrobials by Candida albicans Biofilm Matrix". mBio 7 5 (2016): https://doi.org/10.1128/mBio.01365-16.
    10.1128/mBio.01365-16
  66. Prashanth Garapati; Regina Feil; John Edward Lunn; Patrick Van Dijck; Salma Balazadeh; Bernd Mueller-Roeber. "Transcription Factor Arabidopsis Activating Factor1 Integrates Carbon Starvation Responses with Trehalose Metabolism". Plant Physiology 169 1 (2015): 379-390. https://doi.org/10.1104/pp.15.00917.
    10.1104/pp.15.00917
  67. Yuke Cen; Alessandro Fiori; Patrick Van Dijck. "Deletion of the DNA Ligase IV Gene in Candida glabrata Significantly Increases Gene-Targeting Efficiency". Eukaryotic Cell 14 8 (2015): 783-791. https://doi.org/10.1128/EC.00281-14.
    10.1128/EC.00281-14
  68. Eric F. Kong; Sona Kucharíková; Patrick Van Dijck; Brian M. Peters; Mark E. Shirtliff; Mary Ann Jabra-Rizk; G. S. Deepe, Jr.. "Clinical Implications of Oral Candidiasis: Host Tissue Damage and Disseminated Bacterial Disease". Infection and Immunity 83 2 (2015): 604-613. http://dx.doi.org/10.1128/IAI.02843-14.
    10.1128/IAI.02843-14
  69. Kaat De Cremer; Nicolas Delattin; Katrijn De Brucker; Annelies Peeters; Soña Kucharíková; Evelien Gerits; Natalie Verstraeten; et al. "Oral Administration of the Broad-Spectrum Antibiofilm Compound Toremifene Inhibits Candida albicans and Staphylococcus aureus Biofilm FormationIn Vivo". Antimicrobial Agents and Chemotherapy 58 12 (2014): 7606-7610. https://doi.org/10.1128/AAC.03869-14.
    10.1128/AAC.03869-14
  70. Frédérique Van Hauwenhuyse; Alessandro Fiori; Patrick Van Dijck. "Ascorbic Acid Inhibition of Candida albicans Hsp90-Mediated Morphogenesis Occurs via the Transcriptional Regulator Upc2". Eukaryotic Cell 13 10 (2014): 1278-1289. https://doi.org/10.1128/EC.00096-14.
    10.1128/EC.00096-14
  71. Patrick, Van. "The desiccation tolerant secrets of Selaginella lepidophylla: What we have learned so far?". Plant Physiology and Biochemistry (2014):
    10.1016/j.plaphy.2014.04.015
  72. Hélène Tournu; Patrick Van Dijck. "CandidaBiofilms and the Host: Models and New Concepts for Eradication". International Journal of Microbiology 2012 (2012): 1-16. http://dx.doi.org/10.1155/2012/845352.
    10.1155/2012/845352
Poster em conferência
  1. Ghasemi, Faezeh; Cláudia Barata-Antunes; Ataíde, Patrícia; Alves, João; Isabel, Soares-Silva; Alves, Rosana; Gomes-Gonçalves, Alexandra; et al. "Differential affinity and expression patterns among Candida albicans Ato family members". Trabalho apresentado em I CBMA Open Day & II PhD|Bio Symposium, February 02, 2024, University of Minho, Braga, Portugal, 2024.
  2. Ghasemi, Faezeh; Cláudia Barata-Antunes; Ataíde, Patrícia; Alves, João; Isabel, Soares-Silva; Alves, Rosana; Gomes-Gonçalves, Alexandra; et al. Autor correspondente: Ghasemi, Faezeh. "Candida albicans Acetate transporter orthologues (ATOs): docking and expression studies". Trabalho apresentado em UMinho Research & Innovation Open Days, January 30-31, 2024; University of Minho, Braga, Portugal,, 2024.
  3. Patrícia Ataíde; Ghasemi, Faezeh; Cláudia Barata-Antunes; Gomes-Gonçalves, Alexandra; Alves, Rosana; Casal, Margarida; Brown, Alistair; et al. "Fungi and Nutrition: Expression and Subcellular Localization Patters of Ato2 Transport Protein of Candida albicans". Trabalho apresentado em UMinho Research & Innovation Open Days, January 30-31, 2024; University of Minho, Braga, Portugal, 2024.
  4. Ghasemi, Faezeh; Alexandra Gomes-Gonçalves; Vitor Fernandes; Cláudia Barata-Antunes; Alves, Rosana; Alves Joao; Isabel João soares Silva; et al. "The role of Nutrient Transporters in Candida albicans pathogenesis". Trabalho apresentado em IV International Meeting of the Portuguese Society of Genetics (IMPSG)-Braga, Portugal, 2023.
Pré-impressão
  1. Sofras, Dimitrios; Carolus, Hans; Subotic, Ana; Romero, Celia Lobo; Ennis, Craig L.; Hernday, Aaron D.; Nobile, Clarissa J.; Rybak, Jeffrey M.; Van Dijck, Patrick. "A comparative evaluation of CRISPR-Cas9 allele editing systems inCandida auris: challenging research in a challenging bug". 2025. https://doi.org/10.1101/2025.01.09.632232.
    10.1101/2025.01.09.632232
  2. Wouter Van Genechten; Stefanie Wijnants; Jolien Vreys; Patrick Van Dijck. "Differential sensing by theC. albicansGpr1 receptor results in morphogenesis, ß-glucan masking and survival in macrophages". 2022. https://doi.org/10.1101/2022.11.30.518566.
    10.1101/2022.11.30.518566

Outros

Outra produção
  1. Photochromic fluorophores enable imaging of lowly-expressed proteins in the autofluorescent fungus Candida albicans. 2021. Wouter Van Genechten; Liesbeth Demuyser; Sam Duwé; Wim Vandenberg; Patrick Van Dijck; Peter Dedecker. https://doi.org/10.1101/2021.02.26.433138.
    10.1101/2021.02.26.433138
  2. Genome-wide analysis of experimentally evolved Candida auris reveals multiple novel mechanisms of multidrug-resistance. 2020. Hans Carolus; Siebe Pierson; José F. Muñoz; Ana Subotic; Rita B. Cruz; Christina A. Cuomo; Patrick Van Dijck. https://doi.org/10.1101/2020.09.28.317891.
    10.1101/2020.09.28.317891
  3. Innovative Strategies Toward the Disassembly of the EPS Matrix in Bacterial Biofilms. 2020. Pinto, RM; Soares, FA; Reis, S; Nunes, C; Van Dijck, P.
    10.3389/fmicb.2020.00952
  4. Antifungal Activity and Synergism with Azoles of Polish Propolis. 2018. Katarzyna Gucwa; Barbara Kusznierewicz; Slawomir Milewski; Patrick Van Dijck; Piotr Szweda. https://doi.org/10.20944/preprints201805.0122.v1.
    10.20944/preprints201805.0122.v1
Atividades

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2024/11/01 - 2028/10/31 Unlocking the potential of non-conventional yeast: a superior 3-HP production host
Orientador
 Microbial biotechnology (Doutoramento)
Laboratory of Molecular Cell Biology, Bélgica

Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2024/11/01 - 2028/10/31 Investigating the Effectiveness of Digital Bio Fabrication techniques in Architecture
Coorientador
 Bio-architecture (Doutoramento)
Katholieke Universiteit Leuven, Bélgica
2024/03/05 - 2028/03/04 Characterization of the fungal pathogens infecting avocado fruit in Vietnam and tools to prevent this
Orientador
 Post harvest fungal infection (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2023/11/01 - 2027/10/30 Comparative analysis of resistance-fitness evolution in multidrug resistant Candida species: a role for fitness trade-off compensation and hypermutators?
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2021/11/01 - 2026/10/31 Characterization of the sugar metabolism of Candida glabrata and its role virulence
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2022/02/01 - 2026/01/31 Identification and validation of natural antifungal compounds against bread spoilage organisms as a new biopreservative strategy
Orientador
 Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2021/12/23 - 2025/12/22 Development and characterization of a new generation of probiotics to treat vulvovaginal candidiasis, based on yeast cells and ascospores.
Orientador
 Infection biology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2021/11/01 - 2025/10/31 Unraveling the multidrug resistance, drug tolerance, and collateral sensitivity in the emergent nosocomial fungus C. auris using experimental evolution and multi-omics analysis.
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2021/11/01 - 2025/10/31 Exploration and assessment of probiotic treatment of vaginal candidiasis.
Orientador
 Infection biology; host pathogen interaction (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2022/02/17 - 2025/06/30 Role of trehalose biosynthesis in the virulence and stress tolerance of the human fungal pathogens Candida glabrata and Candida auris
Orientador
 Molecular Microbiology (Doutoramento)
2021/10/08 - 2025/06/30 Investigating the role of DOG genes in Saccharomyces cerevisiae and Candida albicans
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2020/10/27 - 2024/12/11 Unlocking the Potential of Riboflavin Biosynthesis in Candida albicans: From Promising Antifungal Target to Valuable Vitamin Source
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2014/10/01 - 2024/07/05 Molecular Genetic and Transcriptomic Meta-Analysis of Yeast Central Metabolism to Identify Potential Antifungal Targets in Candida albicans
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2019/11/01 - 2024/01/05 Mining the microbial dark matter for novel antifungal compounds
Orientador
 Infection Biology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2019/10/01 - 2023/12/15 Evolutionary insights into Candida auris drug resistance: from novel molecular mechanisms to innovative treatment strategies
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2019/01/01 - 2023/11/20 Development and Optimization of an Industrial Yeast for Lactic Acid Production
Orientador
 Microbial physiology and biotechnology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2012/08/01 - 2023/10/12 The promising potential of non-conventional yeast species for industrial applications
Orientador
 Microbial physiology and biotechnology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2018/10/01 - 2023/04/17 Engineering of a second-generation Saccharomyces cerevisiae strain for the production of 2,3-butanediol from biomass
Orientador
 Microbial physiology and biotechnology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2017/01/01 - 2022/06/29 Development of in vivo models to study Candida infections and innate immune responses
Orientador
 Molecular Microbiology, host-pathogen interactions (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2018/01/01 - 2022/06/17 The glucose metabolism of Candida albicans: exploring the importance of glucose phosphorylation for virulence and Ras1 activation
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2017/08/17 - 2022/03/25 Characterization of the Candida glabrata trehalase enzymes
Orientador
 Molecular Microbiology, host-pathogen interactions (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2018/07/23 - 2022/02/08 Staphylococcus aureus implant-associated biofilms: Development of a novel nanoparticle-based drug delivery system
Orientador
 Infection biology, host-pathogen interactions (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2015/09/15 - 2021/11/15 Candida albicans persister cells and the discovery of novel antifungals
Orientador
 Molecular Microbiology, antifungal drugs (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2013/10/01 - 2021/09/27 Role of the cAMP-PKA pathway on adhesion and pathogenicity in the human fungal pathogen Candida glabrata
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2017/09/14 - 2021/09/20 Synergism of Candida albicans and Staphylococcus aureus in an oral infection mouse model - Exploring underlying mechanisms and treatment options
Orientador
 Molecular Microbiology, host-pathogen interactions (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2016/01/01 - 2021/06/21 Development and application of fluorescent proteins for endogenous imaging of lowly-expressed proteins and elucidating the role of the G-protein coupled receptor, Gpr1, in the virulence of Candida albicans
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2015/03/01 - 2020/09/08 Two trehalase isoforms produced from a single transcript: regulation and function in drought stress tolerance in Arabidopsis thaliana
Orientador
 Plant Molecular Biology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2015/01/01 - 2020/09/08 The genetic basis of two polygenic traits in S. cerevisiae: efficient maltotriose fermentation under ethanol stress and high acetic acid accumulation
Orientador
 Microbial physiology and biotechnology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2013/10/01 - 2019/06/25 A high-throughput Candida albicans two-hybrid (C2H) system: screening for antifungal targets with an emphasis on the cell wall homeostasis
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2013/10/01 - 2019/03/01 Striking Essential Oil: Novel tools and new insights to study the biological activities of essential oils (EOs) and their components (EOCs)
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2013/10/01 - 2019/02/22 Towards a better understanding of ERG11 biology in the model organism Saccharomyces cerevisiae and in the opportunistic human pathogen Candida albicans
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2012/10/01 - 2018/09/12 A fluorescence-based tool for protein-protein interactions analysis and identification of novel processes of fluconazole susceptibility in Candida species
Orientador
 Molecular Microbiology
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2013/10/01 - 2017/11/24 Novel regulatory mechanisms of fluconazole susceptibility and biosensor-based analysis of cAMP-PKA signaling in Candida species
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2012/10/01 - 2017/10/03 Immune response and essential oil activity against pathogenic Candida species
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2012/10/01 - 2017/07/06 Unravelling the mechanism of methionine-induced morphogenesis in Candida albicans
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2010/10/01 - 2016/06/29 Characterization of the Gpr1 and calcineurin dependent regulation of stress resistance in Candida glabrata and development of molecular tools in this organism
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2010/09/01 - 2015/12/11 The role of the FKS1 gene in nosocomial Candida albicans isolates' virulence and antifungal resistance
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2009/02/01 - 2014/09/12 Identification and characterisation of candidate genes for abiotic stress tolerance improvement in plants
Orientador
 Plant Molecular Biology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2009/10/01 - 2014/05/07 Validation of the induced protein aggregation technology using calcineurin as a target and analysis of the role of ascorbic acid on morphogenesis in Candida albicans
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2008/10/01 - 2013/05/23 he role of the Arabidopsis trehalase and the trehalose-6-phosphate phosphatases during drought stress, growth and development
Orientador
 Plant Molecular Biology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2010/10/01 - 2011/06/29 Characterization of a family of Arabidopsis trehalose biosynthesis genes and their role in root development and stress tolerance.
Orientador
 Plant Molecular Biology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2004/10/01 - 2011/05/06 The G protein-coupled receptor Gpr1 is involved in the regulation of trehalose metabolism in the fungal pathogen Candida albicans.
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2007/10/01 - 2011/05/04 Development and application of a Candida albicans two-hybrid system.
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2007/10/01 - 2011/03/11 Development of an in vivo rat subcutaneous Candida albicans biofilm model: characterization and application in the search of new anti-biofilm molecules
Orientador
 Molecular Microbiology, host-pathogen interactions (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2006/10/01 - 2011/02/01 Characterization of the cAMP-PKA pathway in Candida glabrata
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2003/10/01 - 2009/02/20 Functional analysis of the trehalose metabolism gene family in Arabidopsis thaliana
Orientador
 Plant Molecular Biology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
2000/10/01 - 2005/02/04 Characterization of the Candida albicans Tps2 and Cpr1 proteins as potential antifungal targets
Orientador
 Molecular Microbiology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica
1999/10/01 - 2004/05/21 Functionele analyse van trehalose-6-fosfaat synthase genen en de identificatie van nieuwe interagerende componenten uit hogere planten via heterologe expressie in gistcellen
Orientador
 Plant Molecular Biology (Doutoramento)
Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica