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M Cristina L Martins (CM) is Principal Investigator and Leader of the BioEngineered Surfaces Group at i3S/INEB (https://www.i3s.up.pt/research-group.php?groupid=106). She is Vice-Director of INEB and Invited Assistant Professor at Instituto de Ciências Biomédicas Abel Salazar (ICBAS) of the University of Porto. In 2020, she was named Fellow of Biomaterials Science and Engineering (FBSE) by the International Union of Biomaterials Science and Engineering Societies (IUSBSE). CM got her PhD in Engineering Sciences at Faculty of Engineering of the University of Porto (FEUP) in 2003. Her PhD studies were performed at INEB and UWEB (University of Washington Engineered Biomaterials), Seattle, USA. Before starting her research career, she also worked in industry. CM is an expert in the development of biomaterial coatings designed at the nanoscale using self-assembled monolayers (SAMs) and biomedical polymers. Her group is investigating the effect of surface immobilized ligands (proteins/peptides, fatty acid like and glycosylated compounds) in the guiding of specific protein/cell binding to control bacterial infection (e.g., in gastric and skin infection or osteomyelitis prevention) and/or medical devices associated thrombus formation. CM published 115 articles in international peer-reviewed journals (h-index = 35 with 4310 citations (SCOPUS; Feb2025)) 1 book, 11 book chapters and 8 filled patents. She was the Principal Investigator of 8 financed projects (from 29) involving bioengineered strategies to fight infection and one, MOBILIsE, financed from European Commission (H2020) under the topic WIDESPREAD-06-2020 - ERA Chairs- MOBILIsE - ongoing). She supervised/co-supervised 10 PD, 16 PhD (3 ongoing) and 23 MSc (1 ongoing) students.
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Identificação

Identificação pessoal

Nome completo
Maria Cristina Teixeira Lopes Costa Pinto Lopes Martins

Nomes de citação

  • Martins, MCL
  • M. Cristina L. Martins

Identificadores de autor

Ciência ID
CF1F-9660-57FF
ORCID iD
0000-0002-6574-4794
Scopus Author Id
7402262354

Endereços de correio eletrónico

  • cmartins@i3s.up.pt (Profissional)

Websites

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Nanotecnologia - Nanomateriais
  • Ciências da Engenharia e Tecnologias - Biotecnologia Industrial - Bioprodutos Biomateriais
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador independente (B1)
Português (Idioma materno)
Formação
Grau Classificação
2003/03/31
Concluído
 Ciências de Engenharia (Doutoramento)
Especialização em Biomedical Engineering
Universidade do Porto Faculdade de Engenharia, Portugal
"Interaction between Blood Proteins and Surfaces: Self-Assembled Monolayers (SAMs) and Biomedical Polymers" (TESE/DISSERTAÇÃO)
 Aprovado por unanimidade
1994
Concluído
 Post-Graduation in Oenology at Universidade Católica Portuguesa and Charles Sturt University, New South Wales, Australia (Pós-Graduação)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
 14
1989
Concluído
 Engenharia Alimentar (Licenciatura)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
"n/a" (TESE/DISSERTAÇÃO)
 14
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2023 - Atual Investigador principal (carreira) (Investigação) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019 - 2023 Investigador principal (carreira) (Investigação) Instituto Nacional de Engenharia Biomédica, Portugal
Instituto Nacional de Engenharia Biomédica, Portugal
2005 - 2019 Investigador Auxiliar (carreira) (Investigação) Instituto Nacional de Engenharia Biomédica, Portugal
Instituto Nacional de Engenharia Biomédica, Portugal
1992 - 1994 Estagiário de Investigação (Investigação) Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2019 - Atual Professor Associado Convidado (Docente Universitário) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2012 - 2019 Assistente Convidado (Docente Universitário) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2010 - 2013 Assistente Convidado (Docente Universitário) Universidade do Porto Faculdade de Engenharia, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2020/01/29 - Atual Vice-Presidente Instituto Nacional de Engenharia Biomédica, Portugal
Instituto Nacional de Engenharia Biomédica, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2017 - Atual Group Leader - BioEngineered Surfaces Group Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017 - 2023 Scientific coordinator of i3S Biointerfaces and Nanotechnology (BN) Core Facility Instituto Nacional de Engenharia Biomédica, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2004 - 2005 Post-Doctoral Investigator, INEB (FCT scholarship) Fundação para a Ciência e a Tecnologia, Portugal
Instituto Nacional de Engenharia Biomédica, Portugal
2003 - 2004 Researcher, INEB (with a contract from EPARIMED Project) Instituto Nacional de Engenharia Biomédica, Portugal
1996/09 - 2003/03/30 PhD Student Fundação para a Ciência e a Tecnologia, Portugal
Universidade do Porto Faculdade de Engenharia, Portugal
(...)
1999/11/01 - 1999/11/29 Visiting Scientist, Prof. Ji Jian’s Lab (Department of Polymer Science, Zhejiang University, Hangzhou, China) Fundação para a Ciência e a Tecnologia, Portugal
Instituto Nacional de Engenharia Biomédica, Portugal
1998/09 - 1999/03 Visiting Scientist, Prof. Buddy Ratner’s Lab (UWEB, University of Washington Engineered Biomaterials, Seattle, Washington, USA) Fundação para a Ciência e a Tecnologia, Portugal
UWEB, University of Washington Engineered Biomaterials, Seattle, Washington, USA, Estados Unidos
(...)
1994 - 1996 Quality Control Manager, Cork industry J.C. Ribeiro, Lda, Portugal
1990 - 1991 Quality Control Manager, Canning Industry Fábrica de Conservas Madrugada, Lda , Portugal
1988 - 1989 Research trainee, Biotechnology company (Gist-Brocades, Delft, Netherland) Gist-Brocades, Países Baixos
Projetos

Projeto

Designação Financiadores
2025/02/01 - Atual BiDress-Bioactive wound Dressing for infected chronic wounds
2023.11469.PEX
Investigador
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Em curso
2021/01/01 - 2026/06/30 MOBILIsE: Molecular Bioengineering in health ERA Chair / H2020
Grant agreement ID: 951723
Investigador responsável
Instituto Nacional de Engenharia Biomédica, Portugal
 European Commission
Em curso
2022/06 - 2025/06 NanoPyl® A breakthrough approach for Helicobacter pylori control
CI22-00115
Investigador
CaixaForum Barcelona
Em curso
2023/03/01 - 2025/02/28 BIOGEN-Biofilm genetic regulation in the treatment of Chronic Wound Infection
2022.04739.PTDC
Investigador
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2021/03 - 2024/02 FETBIO- Fetal-inspired hierarchical biomaterials for regeneration in a harsh microenvironment: the nucleus of the intervertebral disc (FETBIO)
PTDC/BTM-MAT/0438/2020
Co-Investigador Responsável (Co-IR)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2021/03 - 2023/03 Bio2Skin Advanced- Development of a new generation of adhesives with antiseptic, regenerative and adhesive proprieties to prevent and / or treat skin lesions caused by use of conventional medical adhesives. Project in co-promotion with the company BestHealth4U Ltd
NORTE-01-0247-FEDER-047225
Investigador responsável
Instituto Nacional de Engenharia Biomédica, Portugal
Concluído
2018/07/01 - 2022/06 AntINFECT- Bioengineered Advanced Therapies for Problematic Infected Wounds
PTDC/NAN-MAT/31781/2017
Investigador responsável
Instituto Nacional de Engenharia Biomédica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2018/07/03 - 2021/12 Nano4Film: Circumventing surgical removal of biofilms infected implants: a nano-based, selective and targeted approach
POCI-01-0145-FEDER-031444
Investigador
REQUIMTE LAQV Porto, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2017/10 - 2021/09 mCBEEs - Advanced integrative solutions to Corrosion problems beyond microscale: towards long-term durability of miniaturized Biomedical, Electronic and Energy systems / H2020-Marie Sklodowska-Curie actions -ITN 2017
Marie Sklodowska-Curie grant agreement No 764977
Investigador
Instituto Nacional de Engenharia Biomédica, Portugal
 European Commission Marie Sklodowska-Curie Actions
Concluído
2016/06/01 - 2019/12/31 PYLORIBINDERS - Helicobacter pylori specific biomaterials for antibiotic-free treatment/diagnostic of gastric infection <br>
PTDC/CTM-BIO/4043/2014
grant.Provided by PTCRIS: 142674
Investigador responsável
Instituto Nacional de Engenharia Biomédica, Portugal
 Fundação para a Ciência e a Tecnologia

Stichting Weten
Concluído
2014/04/01 - 2016/03/31 Biofunctional coatings for cardiovascular interventional devices / Portugal-China Joint Innovation Centre for Advanced Materials (JICAM2013)
JICAM2013
Investigador responsável
Instituto Nacional de Engenharia Biomédica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2012/03/01 - 2015/08/31 PYLORICIDAL - Engineered biomaterials with Helicobacter PYLORI bacteriCIDAL effect
PTDC/CTM-BPC/121149/2010
grant.Provided by PTCRIS: 121149
Investigador responsável
Instituto Nacional de Engenharia Biomédica, Portugal
 Fundação para a Ciência e a Tecnologia

Stichting Weten
Concluído
2014/03 - 2015/08 SweetMic - Helicobacter pylori entrapment using “sweet” microsponges: a new alternative for gastric infection treatment
Provided by PTCRIS: 133784
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2010/03 - 2013/08 CHITOSAMP - CHITOSan-AntiMicrobial Peptide-based biomaterials for the treatment of osteomyelitis
PTDC/CTM/101484/2008
grant.Provided by PTCRIS: 101484
Investigador
Universidade do Porto Faculdade de Ciências, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
Fundação para a Ciência e a Tecnologia

Stichting Weten
Concluído
2008/03/01 - 2011/08/31 A strategy for preventing H. pylori-associated gastric cancer based on materials with specific receptors to the bacteria - from SAMs to Gly-R chitosan microspheres
PTDC/CTM/65330/2006
grant.Provided by PTCRIS: 65330
Investigador responsável
Instituto Nacional de Engenharia Biomédica, Portugal
 Fundação para a Ciência e a Tecnologia

Stichting Weten
Concluído
2005/05 - 2008/06 Immobilization of ligands to albumin and thrombin on self-assembled monolayers - influence on thrombus formation and inflammatory reactions
Provided by PTCRIS: 55644
Investigador
Fundação para a Ciência e a Tecnologia

Outro

Designação Financiadores
2021/03 - 2022/02 NanoPyl: Lipid Nanoparticles for Massive Eradication of Helicobacter pylori BIP-Proof (Business Ignition Programme) Support program for the development of proof of concept of the University of Porto).
Business Ignition Programme
Investigador
Instituto Nacional de Engenharia Biomédica, Portugal
Concluído
Produções

Publicações

Artigo em conferência
  1. Fonseca DR, Alves PM, Neto E, Custódio B, Guimarães S, Martins M, Gomes A, Gomes P, Pereira R, Freitas P, Parreira P, Ma. "Watch out Helicobacter: chitosan nanoparticles decorated with antimicrobial peptides for gastric infection,". Trabalho apresentado em 36th Workshop of the European Helicobacter and Microbiota Study Group (EHMSG 2023), Antuerpia, 2023.
  2. Fonseca DR, Alves PM, Neto E, Custódio B, Guimarães S, Moura D, Annis F, Martins M, Gomes A, Teixeira C, Gomes P, Pereir. "A BIOMATERIAL APPROACH BASED ON CHITOSAN NANOPARTICLES FUNCTIONALIZED WITH ANTIMICROBIAL PEPTIDES: THE LAST PIECE IN THE PUZZLE AGAINST HELICOBACTER PYLORI". Trabalho apresentado em Gastroenterology, Chicago, 2023.
    Publicado
  3. Seabra C, Pedro N, Nunes C, Reis S, Pereira L, Parreira P, Martins MCL. "NANOPYL®: A BIOENGINEERED APPROACH FOR HELICOBACTER PYLORI MANAGEMENT.". Trabalho apresentado em Gastroenterology 164 (6), S-376 (Sa1367), Chicago, 2023.
    Publicado
  4. M. Cristina L. Martins. "Seabra CL, Nunes C, Reis CA, Gonçalves IC, Reis S, Martins MCL. Anti-Helicobacter pylori activity of lipid nanoparticles loaded with an omega-3 polyunsaturated fatty acid. Helicobacter, 21: 69–177". Trabalho apresentado em 29th International Workshop on Helicobacter and Microbiota in Inflammation and Cancer (EHMSG), Alemanha, 2016.
    Publicado • 10.1111/hel.12344
  5. M. Cristina L. Martins. "Henriques PC, Costa LM, Seabra CL, Silva-Carvalho R, Junqueira-Neto S, Antunes B, Magalhães A, Reis C, Gartner F, Touati E, Gomes J, Martins MCL, Gonçalves IC (2016). Chitosan microspheres can fight Helicobacter pylori gastric infection in mice. Front. Bioeng Biotechnol. Conference Abstract: 10th World Biomaterials Congress. doi: 0.3389/conf.FBIOE.2016.01.02". 2016.
  6. Queirós, R.B.; Gouveia, C.; Martins, M.C.L.; Jorge, P.A.S.. "Self-referenced label free biosensors based on differential fiber optic interferometry". 2014.
    10.1117/12.2040919
  7. Coelho, L.; Queirós, R.B.; Santos, J.L.; Martins, M.C.L.; Viegas, D.; Jorge, P.A.S.. "DNA-Aptamer optical biosensors based on a LPG-SPR optical fiber platform for point-of-care diagnostic". 2014.
    10.1117/12.2040892
  8. M. Cristina L. Martins. "Nogueira F, Goncalves IC; Martins MCL. Helicobacter pylori interaction with mucoadhesive films under gastric conditions. HELICOBACTER. Vol:18; Special Issue:SI Suppl:1; p:97-97;". 2013.
    Publicado
  9. M. Cristina L. Martins. "Goncalves IC, Fernandes M, Magalhães A, Rodrigues IV, Reis CA, Martins MCL. Helicobacter pylori-binding biomaterials as alternative treatment for gastric infection. HELICOBACTER. Vol:18; Special Issue:SI; Suppl:1;p:132-132". 2013.
    Publicado
  10. M. Cristina L. Martins. "Costa F, Maia S, Gomes P, Martins MCL. hLF1-11 synthesis and immobilization onto chitosan thin films to create antimicrobial coatings. JOURNAL OF PEPTIDE SCIENCE. Volume:18; Supplement: 1; S199-S199". 2012.
    Publicado
  11. Costa, F.; Maia, S.; Gomes, P.; Martins, M.C.L.. "Covalent immobilization of human lactoferrin-derived peptide (hLF1-11) for the development of an antimicrobial surface". 2011.
  12. Parreira, P.; Magalhães, A.; Reis, C.A.; Leckb, D.; Martins, M.C.L.. "Engineering surfaces to trigger helicobacter pylori adhesion". 2011.
  13. M. Cristina L. Martins. "Costa F, Maia S, Gomes P, Martins MCL. Covalent immobilization of human lactoferrin-derived peptide (hLF1-11) for the development of an antimicrobial surface: 24th European Conference on Biomaterials, EBS 2011". 2011.
  14. M. Cristina L. Martins. "Gonçalves I, Fernandes M, Magalhães A, Reis CA, Martins MCL. Chitosan microspheres to prevent/remove helicobacter pylori gastric colonization. 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials. 2011, 1p; Code 100603". 2011.
  15. M. Cristina L. Martins. "Parreira P, Reis CA, Magalhães A, Leckband D, Martins MCL. Immobilization of a Specific Receptor for H. pylori Using Model Surfaces. HELICOBACTER. 2009, 14(4):410-411.". 2009.
  16. M. Cristina L. Martins. "Oliveira JR, Martins MCL, Gomes P. Selective O-alkynylation of chitosan: towards “clickable” cationic chitosans. 8th International Meeting of the Portuguese Carbohydrate Group – Glupor 8, Braga (Portugal), September 2009. Book of Abstracts of the Glupor 8". 2009.
  17. Freitas, S.C.; Barbosa, M.A.; Martins, M.C.L.. "Immobilization of thrombin inhibitors on self-assembled monolayers (SAMs)". 2008.
  18. Gonçalves, R.; Martins, M.C.L.; Almeida -Porada, G.; Barbosa, M.. "Functionalization of self -assembled monolayers with the repeate d unit of notch ligands". 2008.
  19. Maciel, J.; Martins, M.C.L.; Barbosa, M.A.. "The influence of cell culture media in the stability of self-assembled monolayers". 2008.
  20. Gonalves, I.C.; Martins, M.C.L.; Barbosa, J.N.; Ratner, B.D.; Barbosa, M.A.. "Influence of plasma proteins in leukocyte adhesion to self-assembled monolayers". 2008.
  21. Martins, M.C.L.; Curtin, S.A.; Freitas, S.C.; Salgueiro, P.; Ratner, B.D.; Barbosa, M.A.. "Immobilization of poly(lysine, leucine) on EG4-terminated SAMs: Effect of peptide concentration on blood deheparinization". 2008.
  22. M. Cristina L. Martins. "Parreira P, Reis CA, Magalhães A, Leckband D, Martins MCL. Helicobacter pylori adhesion to gold, hydrophilic and hydrophobic self-assembled monolayers (SAMs). HELICOBACTER. 2008, 13(5):415-415". 2008.
  23. M. Cristina L. Martins. "Martins, M.C.L. and Curtin, S.A. and Freitas, S.C. and Salgueiro, P. and Ratner, B.D. and Barbosa, M.A. Engineering surfaces for blood deheparinization using an heparin-binding peptide: European Cells and Materials 2007. Volume 14, Issue SUPPL.3, November 2007, Page 96". 2007.
  24. M. Cristina L. Martins. "Gonçalves IC, Martins MCL, Barbosa MA, Naeemi E, Ratner BD. Platelet adhesion and activation modulated by selective adsorption of proteins to self-assembled monolayers. European Cells and Materials. 2007, vol 14, Suppl.3 (page 97).". 2007.
  25. M. Cristina L. Martins. "Barrias CC, Ribeiro CC, Martins MCL, Barbosa MA, Rodrigues D, Miranda MCS. Calcium phosphate microspheres for localised delivery of a therapeutic enzyme. BIOCERAMICS 18. 2006, 309-311: 903-906". 2006.
  26. M. Cristina L. Martins. "Barbosa MA, Martins MCL, Barbosa JN. Interactions of cells and proteins with molecularly designed surfaces. European Cells and Materials Vol. 7. Suppl. 1, 2004 (page 17)". 2004.
Artigo em revista
  1. Pinho, Ana Sofia; Pereira, Renato; Pereira, Mariana; Rai, Akhilesh; Ferreira, Lino; Martins, Maria Cristina Lopes; Parreira, Paula. "Cholesterol Functionalized Nanoparticles Are Effective against Helicobacter pylori, the Gastric Bug: A Proof-of-Concept Study". Advanced Healthcare Materials (2025): https://doi.org/10.1002/adhm.202404065.
    10.1002/adhm.202404065
  2. Costa, Natália A.; Ribeiro, Ana R.; Rossi, André L.; Monteiro, Cláudia; Lisboa-Filho, Paulo N.; Martins, M. Cristina L.. "Effect of NaOH etching and oxygen plasma treatments on surface characteristics and their potential to activate micro-arc oxidized TiO2 coatings". Applied Surface Science 682 (2025): 161748. https://doi.org/10.1016/j.apsusc.2024.161748.
    10.1016/j.apsusc.2024.161748
  3. Costa, B.; Coelho, J.; Silva, V.; Shahrour, H.; Costa, N.A.; Ribeiro, A.R.; Santos, S.G.; et al. "Dhvar5- and MSI78-coated titanium are bactericidal against methicillin-resistant Staphylococcus aureus, immunomodulatory and osteogenic". Acta Biomaterialia 191 (2025): 98-112. https://doi.org/10.1016/j.actbio.2024.11.016.
    10.1016/j.actbio.2024.11.016
  4. Spajic, Ivan; Morais, Miguel Gonçalves; Monteiro, Cláudia; Martins, M. Cristina L.; Pêgo, Ana Paula; Milošev, Ingrid. "Biocompatibility and antibacterial properties of medical stainless steel and titanium modified by alumina and hafnia films prepared by atomic layer deposition". Journal of Materials Science: Materials in Medicine 35 1 (2024): https://doi.org/10.1007/s10856-024-06841-8.
    10.1007/s10856-024-06841-8
  5. Inês Cruz; Stefano Di Bella; Mario D’Oria; Cristina Lagatolla; M. Cristina L. Martins; Cláudia Monteiro. "Vascular Graft Impregnation with a Fosfomycin/Oritavancin Combination to Prevent Early Infection". Pharmaceutics (2024): https://doi.org/10.3390/pharmaceutics16111348.
    10.3390/pharmaceutics16111348
  6. Costa, B.; Alves, P.M.; Fonseca, D.R.; Campos, F.; Monteiro, A.C.; Shahrour, H.; Gomes, A.; et al. "Dhvar5-chitosan nanogels and their potential to improve antibiotics activity". International Journal of Biological Macromolecules 277 (2024): 134059. https://doi.org/10.1016/j.ijbiomac.2024.134059.
    10.1016/j.ijbiomac.2024.134059
  7. Rute Chitas; Diana R. Fonseca; Paula Parreira; M. Cristina L. Martins. "Targeted nanotherapeutics for the treatment of Helicobacter pylori infection". Journal of Biomedical Science (2024): https://doi.org/10.1186/s12929-024-01068-9.
    10.1186/s12929-024-01068-9
  8. Xinyi Li; Jiarong Wang; Yirong Guo; Honglin Qian; Yiduo Chen; Yanchen Chen; Jing Wang; et al. "Non-swelling polyelectrolyte complex hydrogels with tissue-matchable mechanical properties for versatile wet wound closure". Composites Part B: Engineering (2024): https://doi.org/10.1016/j.compositesb.2024.111456.
    10.1016/j.compositesb.2024.111456
  9. Pedro M. Alves; Cristina C. Barrias; Paula Gomes; M. Cristina L. Martins. "How can biomaterial-conjugated antimicrobial peptides fight bacteria and be protected from degradation?". Acta Biomaterialia (2024): https://doi.org/10.1016/j.actbio.2024.04.043.
    10.1016/j.actbio.2024.04.043
  10. Spósito, Larissa; Fonseca, Diana; Gonçalves Carvalho, Suzana; Sábio, Rafael Miguel; Marena, Gabriel Davi; Bauab, Taís Maria; Bagliotti Meneguin, Andréia; et al. "Engineering resveratrol-loaded chitosan nanoparticles for potential use against Helicobacter pylori infection". European Journal of Pharmaceutics and Biopharmaceutics 199 (2024): 114280. https://doi.org/10.1016/j.ejpb.2024.114280.
    10.1016/j.ejpb.2024.114280
  11. Diana R. Fonseca; Rute Chitas; Paula Parreira; M.Cristina L. Martins. "How to manage Helicobacter pylori infection beyond antibiotics: The bioengineering quest". Applied Materials Today 37 (2024): 102123. https://doi.org/10.1016/j.apmt.2024.102123.
    Acesso aberto • Publicado • 10.1016/j.apmt.2024.102123
  12. Luísa Fialho; João Albuquerque; A. Sofia Pinho; Ana Margarida Pereira; Cláudia Monteiro; Nélson Oliveira; Sónia Ferreira; M. Cristina L. Martins. "Exploring innovative adhesive approaches to manage medical adhesive-related skin injuries (MARSI)". International Journal of Adhesion and Adhesives (2024): https://doi.org/10.1016/j.ijadhadh.2024.103636.
    10.1016/j.ijadhadh.2024.103636
  13. Pedro M. Alves; Diana R. Fonseca; Sílvia J. Bidarra; Ana Gomes; Paula Gomes; Cristina C. Barrias; M. Cristina L. Martins. "Norbornene-chitosan nanoparticles with and without a conjugated VEGF-peptide analog to promote vascularization". Materials Today Chemistry (2024): https://doi.org/10.1016/j.mtchem.2024.101942.
    10.1016/j.mtchem.2024.101942
  14. Fonseca DR, Alves PM, Neto E, Custódio B, Guimarães S, Moura D, Annis F, Martins M, Gomes A, Teixeira C, Gomes P, Pereir. "One-pot microfluidics to engineer chitosan nanoparticles conjugated with antimicrobial peptides using “photoclick” chemistry: validation using the gastric bacterium Helicobacter pylori". ACS Applied Materials & Interfaces (2024): https://doi.org/10.1021/acsami.3c18772.
    Acesso aberto • No prelo
  15. Bruno Ribeiro; Ruben Offoiach; Claudia Monteiro; Miguel R. G. Morais; M. Cristina L. Martins; Ana Paula Pêgo; Elisa Salatin; Lorenzo Fedrizzi; Maria Lekka. "Electrodeposition of Zn and Cu Nanoparticles into TiO2 Nanotubes on Ti6Al4V: Antimicrobial Effect against S. Epidermidis and Cytotoxicity Assessment". Micro (2024): https://doi.org/10.3390/micro4010007.
    10.3390/micro4010007
  16. Seabra, Catarina Leal; Pinho, A. Sofia; Nunes, Cláudia; Amorim, Irina; Pedro, Nicole; Henriques, Patrícia; Monteiro, Cláudia; et al. "Paving the way for a non-antibiotic and microbiota friendly therapy for Helicobacter pylori: In vitro and in vivo performance of lipid nanoparticles". Helicobacter 29 1 (2024): https://doi.org/10.1111/hel.13050.
    10.1111/hel.13050
  17. Redondo-Gómez, Carlos; Parreira, Paula; Martins, M. Cristina L.; Azevedo, Helena S.. "Peptide-based self-assembled monolayers (SAMs): what peptides can do for SAMs and vice versa". Chemical Society Reviews (2024): http://dx.doi.org/10.1039/d3cs00921a.
    Acesso aberto • 10.1039/d3cs00921a
  18. Mariana Barbosa; Pedro M. Alves; Fabíola Costa; Cláudia Monteiro; Paula Parreira; Cátia Teixeira; Paula Gomes; Maria Cristina L. Martins. "Influence of Immobilization Strategies on the Antibacterial Properties of Antimicrobial Peptide-Chitosan Coatings". Pharmaceutics (2023): https://doi.org/10.3390/pharmaceutics15051510.
    10.3390/pharmaceutics15051510
  19. Maura Cimino; Paula Parreira; Victoria Leiro; Aureliana Sousa; Raquel M. Gonçalves; Cristina C. Barrias; M. Cristina L. Martins. "Enhancement of hMSC In Vitro Proliferation by Surface Immobilization of a Heparin-Binding Peptide". Molecules (2023): https://doi.org/10.3390/molecules28083422.
    10.3390/molecules28083422
  20. Barbosa, Mariana; Pedro Alves; Costa, Fabíola; Parreira, Paula; Cátia Teixeira; Paula Gomes; M. Cristina L. Martins. Autor correspondente: M. Cristina L. Martins. "Influence of immobilization strategies on the antibacterial properties of Dhvar5-chitosan coatings". (2023):
    Submetido
  21. António Miguel Ramôa; Filipa Campos; Luís Moreira; Cátia Teixeira; Victoria Leiro; Paula Gomes; José das Neves; M. Cristina L. Martins; Cláudia Monteiro. "Antimicrobial peptide-grafted PLGA-PEG nanoparticles to fight bacterial wound infections". Biomaterials Science (2023): https://doi.org/10.1039/D2BM01127A.
    10.1039/D2BM01127A
  22. Yu-xian Lai; Jia-yin Fu; Shao-fei Wu; Ren-yun Li; Jia-qi Hu; You-xiang Wang; M. Cristina L. Martins; et al. "A pDNA/rapamycin nanocomposite coating on interventional balloons for inhibiting neointimal hyperplasia". Journal of Materials Chemistry B (2023): https://doi.org/10.1039/D3TB00344B.
    10.1039/D3TB00344B
  23. Leila Mousavifar; Paula Parreira; Alexis Taponard; Vanessa C. D. Graça; M. Cristina L. Martins; René Roy. "Validation of Selective Capture of Fimbriated Uropathogenic Escherichia coli by a Label-free Engineering Detection System Using Mannosylated Surfaces". ACS Applied Bio Materials (2022): https://doi.org/10.1021/acsabm.2c00838.
    10.1021/acsabm.2c00838
  24. Rute Chitas; Cláudia Nunes; Salette Reis; Paula Parreira; Maria Cristina L. Martins. "How Charge, Size and Protein Corona Modulate the Specific Activity of Nanostructured Lipid Carriers (NLC) against Helicobacter pylori". Pharmaceutics (2022): https://doi.org/10.3390/pharmaceutics14122745.
    10.3390/pharmaceutics14122745
  25. Rita M. Pinto; Catarina Leal Seabra; Martine De Jonge; M. Cristina L. Martins; Patrick Van Dijck; Salette Reis; Cláudia Nunes. "Antibiofilm Combinatory Strategy: Moxifloxacin-Loaded Nanosystems and Encapsulated N-Acetyl-L-Cysteine". Pharmaceutics (2022): https://doi.org/10.3390/pharmaceutics14112294.
    10.3390/pharmaceutics14112294
  26. Pedro M. Alves; Rúben F. Pereira; Beatriz Costa; Natália Tassi; Cátia Teixeira; Victoria Leiro; Cláudia Monteiro; et al. "Thiol–Norbornene Photoclick Chemistry for Grafting Antimicrobial Peptides onto Chitosan to Create Antibacterial Biomaterials". ACS Applied Polymer Materials (2022): https://doi.org/10.1021/acsapm.2c00563.
    10.1021/acsapm.2c00563
  27. Daniela Lopes-de-Campos; Catarina Seabra; Rita M Pinto; M. A. Slowinski; Bruno Sarmento; Claudia Nunes; M. Cristina L. Martins; S. Reis. Autor correspondente: S. Reis. "Targeting and Killing the Ever-Challenging Ulcer Bug". International Journal of Pharmaceutics 617 5 (2022): https://doi.org/10.1016/j.ijpharm.2022.121582.
    Publicado • 10.1016/j.ijpharm.2022.121582
  28. Fonseca, Diana R.; Moura, Ana; Leiro, Victoria; Silva-Carvalho, Ricardo; Estevinho, Berta N.; Seabra, Catarina L.; Henriques, Patrícia C.; et al. "Grafting MSI-78A onto chitosan microspheres enhances its antimicrobial activity". Acta Biomaterialia 137 (2022): 186-198. http://dx.doi.org/10.1016/j.actbio.2021.09.063.
    Publicado
  29. Rai, Akhilesh; Ferrão, Rafaela; Palma, Paulo; Patricio, Tatiana; Parreira, Paula; Anes, Elsa; Tonda-Turo, Chiara; et al. "Antimicrobial peptide-based materials: opportunities and challenges". Journal of Materials Chemistry B 10 (2022): 2384-2429. http://dx.doi.org/10.1039/d1tb02617h.
    Publicado
  30. Yue Huang; Dan Li; Deliang Wang; Xiaohui Chen; Lino Ferreira; M. Cristina L. Martins; Youxiang Wang; Qiao Jin; Dong Wang; Benzhong Tang, Jian Ji.. "NIR-II emissive polymer AIEgen for imaging-guided photothermal elimination of bacterial infection". (2022): https://doi.org/10.1016/j.biomaterials.2022.121579.
    Publicado
  31. Alves, P.M.; Barrias, C.C.; Gomes, P.; Martins, M.C.L.. "Smart biomaterial-based systems for intrinsic stimuli-responsive chronic wound management". Materials Today Chemistry 22 (2021): 100623. http://dx.doi.org/10.1016/j.mtchem.2021.100623.
    Publicado • 10.1016/j.mtchem.2021.100623
  32. Parreira, Paula; Martins, M. Cristina L.. "The biophysics of bacterial infections: Adhesion events in the light of force spectroscopy". The Cell Surface 7 (2021): 100048. http://dx.doi.org/10.1016/j.tcsw.2021.100048.
    10.1016/j.tcsw.2021.100048
  33. Gomes, Ana; Bessa, Lucinda J.; Fernandes, Iva; Ferraz, Ricardo; Monteiro, Cláudia; L. Martins, M. Cristina; Mateus, Nuno; et al. Autor correspondente: L. Martins, M. Cristina. "Disclosure of a Promising Lead to Tackle Complicated Skin and Skin Structure Infections: Antimicrobial and Antibiofilm Actions of Peptide PP4-3.1". Pharmaceutics 13 11 (2021): 1962. http://dx.doi.org/10.3390/pharmaceutics13111962.
    Publicado
  34. Ana Gomes; Lucinda J. Bessa; Iva Fernandes; Ricardo Ferraz; Cláudia Monteiro; M. Cristina L. Martins; Nuno Mateus; et al. "Disclosure of a Promising Lead to Tackle Complicated Skin and Skin Structure Infections: Antimicrobial and Antibiofilm Actions of Peptide PP4-3.1". Pharmaceutics (2021): https://doi.org/10.3390/pharmaceutics13111962.
    10.3390/pharmaceutics13111962
  35. Costa, Bruna; Martínez-de-Tejada, Guillermo; Gomes, Paula A. C.; L. Martins, M. Cristina; Costa, Fabíola. "Antimicrobial Peptides in the Battle against Orthopedic Implant-Related Infections: A Review". Pharmaceutics 13 11 (2021): 1918. http://dx.doi.org/10.3390/pharmaceutics13111918.
    Publicado
  36. Bruna Costa; Guillermo Martínez-de-Tejada; Paula A. C. Gomes; M. Cristina L. Martins; Fabíola Costa. "Antimicrobial Peptides in the Battle against Orthopedic Implant-Related Infections: A Review". Pharmaceutics 13 11 (2021): 1918-1918. https://doi.org/10.3390/pharmaceutics13111918.
    10.3390/pharmaceutics13111918
  37. Pinto, Rita M.; Monteiro, Claudia; Costa Lima, Sofia A.; Casal, Susana; Van Dijck, Patrick; Martins, M. Cristina L.; Nunes, Cláudia; Reis, Salette. "N-Acetyl-l-cysteine-Loaded Nanosystems as a Promising Therapeutic Approach Toward the Eradication of Pseudomonas aeruginosa Biofilms". ACS Applied Materials & Interfaces 13 36 (2021): 42329-42343. http://dx.doi.org/10.1021/acsami.1c05124.
    Publicado • 10.1021/acsami.1c05124
  38. Pereira, Andreia T.; Schneider, Karl H.; Henriques, Patrícia C.; Grasl, Christian; Melo, Sofia F.; Fernandes, Inês P.; Kiss, Herbert; et al. "Graphene Oxide Coating Improves the Mechanical and Biological Properties of Decellularized Umbilical Cord Arteries". ACS Applied Materials & Interfaces 13 28 (2021): 32662-32672. http://dx.doi.org/10.1021/acsami.1c04028.
    Publicado • 10.1021/acsami.1c04028
  39. Matinha-Cardoso, Jorge; Mota, Rita; Gomes, Luciana C.; Gomes, Marisa; Mergulhão, Filipe J.; Tamagnini, Paula; Martins, M. Cristina L.; Costa, Fabíola. "Surface activation of medical grade polyurethane for the covalent immobilization of an anti-adhesive biopolymeric coating". Journal of Materials Chemistry B 9 17 (2021): 3705-3715. http://dx.doi.org/10.1039/d1tb00278c.
    Publicado • 10.1039/d1tb00278c
  40. Andreia Pereira; Patrícia C. Henriques; A. L. Pires; K. H. Schneider; André Pereira; M. Cristina L. Martins; Fernão Magalhães; H. Bergmeister; Inês C. Gonçalves. "Graphene-based materials: the key to a successful application of pHEMA as a blood contacting device". Biomaterials Science (2021): https://doi.org/10.1039/D0BM01699C.
    Publicado
  41. Andreia T. Pereira; Patrícia C. Henriques; Karl H. Schneider; Ana L. Pires; André M. Pereira; Maria Cristina L. Martins; Fernão D. Magalhães; Helga Bergmeister; Inês C. Gonçalves. "Graphene-based materials: the key for the successful application of pHEMA as a blood-contacting device". Biomaterials Science (2021): https://doi.org/10.1039/D0BM01699C.
    10.1039/D0BM01699C
  42. Henriques, Patrícia C.; Costa, Lia M.; Seabra, Catarina L.; Antunes, Bernardo; Silva-Carvalho, Ricardo; Junqueira-Neto, Susana; Maia, André F.; et al. "Orally administrated chitosan microspheres bind Helicobacter pylori and decrease gastric infection in mice". Acta Biomaterialia 114 (2020): 206-220. http://dx.doi.org/10.1016/j.actbio.2020.06.035.
    10.1016/j.actbio.2020.06.035
  43. Monteiro, Cláudia; Fernandes, Hélia; Oliveira, Diana; Vale, Nuno; Barbosa, Mariana; Gomes, Paula; L. Martins, M. Cristina. "AMP-Chitosan Coating with Bactericidal Activity in the Presence of Human Plasma Proteins". Molecules 25 13 (2020): 3046. http://dx.doi.org/10.3390/molecules25133046.
    Publicado • 10.3390/molecules25133046
  44. Costa, Bruna; Mota, Rita; Tamagnini, Paula; L. Martins, M. Cristina; Costa, Fabíola. "Natural Cyanobacterial Polymer-Based Coating as a Preventive Strategy to Avoid Catheter-Associated Urinary Tract Infections". Marine Drugs 18 6 (2020): 279. http://dx.doi.org/10.3390/md18060279.
    Publicado • 10.3390/md18060279
  45. Maura Cimino; Paula Parreira; Sílvia J. Bidarra; Raquel M. Gonçalves; Cristina C. Barrias; M. Cristina L. Martins. "Effect of surface chemistry on hMSC growth under xeno-free conditions". Colloids and Surfaces B: Biointerfaces 189 (2020): 110836-110836. https://doi.org/10.1016/j.colsurfb.2020.110836.
    10.1016/j.colsurfb.2020.110836
  46. Cimino, Maura; Parreira, Paula; Bidarra, Sílvia J.; Gonçalves, Raquel M.; Barrias, Cristina C.; Martins, M. Cristina L.. "Effect of surface chemistry on hMSC growth under xeno-free conditions". Colloids and Surfaces B: Biointerfaces 189 (2020): 110836. http://dx.doi.org/10.1016/j.colsurfb.2020.110836.
    10.1016/j.colsurfb.2020.110836
  47. Paula Parreira; M. Cristina L. Martins. "The biophysics of bacterial infections: adhesion events in the light of force spectroscopy. The Cell Surface: special issue on Biophysics of Microbial Adhesion. 2020.". (2020):
    Aceite para publicação
  48. Paula Parreira; Claudia Monteiro; Vanessa Graça; Joana Gomes; Sílvia Maia; Paula Gomes; Inês C. Gonçalves; M. Cristina L. Martins. "Surface Grafted MSI-78A Antimicrobial Peptide has High Potential for Gastric Infection Management". Scientific Reports (2019): https://doi.org/10.1038/s41598-019-53918-4.
    10.1038/s41598-019-53918-4
  49. Claudia Monteiro; Fabíola Costa; Anna Maria Pirttilä; Mysore V. Tejesvi; M. Cristina L. Martins. "Prevention of urinary catheter-associated infections by coating antimicrobial peptides from crowberry endophytes". Scientific Reports 9 1 (2019): https://doi.org/10.1038/s41598-019-47108-5.
    10.1038/s41598-019-47108-5
  50. Pereira, Andreia T.; Henriques, Patrícia C.; Costa, Paulo C.; Martins, Maria Cristina L.; Magalhães, Fernão D.; Gonçalves, Inês C.. "Graphene oxide-reinforced poly(2-hydroxyethyl methacrylate) hydrogels with extreme stiffness and high-strength". Composites Science and Technology 184 (2019): 107819. http://dx.doi.org/10.1016/j.compscitech.2019.107819.
    10.1016/j.compscitech.2019.107819
  51. Pinto, Rita M; Lopes-de-Campos, Daniela; Martins, M Cristina L; Van Dijck, Patrick; Nunes, Cláudia; Reis, Salette. "Impact of nanosystems in Staphylococcus aureus biofilms treatment". FEMS Microbiology Reviews (2019): http://dx.doi.org/10.1093/femsre/fuz021.
    10.1093/femsre/fuz021
  52. Maitz, Manfred F.; Martins, M. Cristina L.; Grabow, Niels; Matschegewski, Claudia; Huang, Nan; Chaikof, Elliot L.; Barbosa, Mário A.; Werner, Carsten; Sperling, Claudia. "The blood compatibility challenge. Part 4: Surface modification for hemocompatible materials: Passive and active approaches to guide blood-material interactions". Acta Biomaterialia 94 (2019): 33-43. http://dx.doi.org/10.1016/j.actbio.2019.06.019.
    10.1016/j.actbio.2019.06.019
  53. Costa, Bruna; Mota, Rita; Parreira, Paula; Tamagnini, Paula; L. Martins, M. Cristina; Costa, Fabíola. "Broad-Spectrum Anti-Adhesive Coating Based on an Extracellular Polymer from a Marine Cyanobacterium". Marine Drugs 17 4 (2019): 243. http://dx.doi.org/10.3390/md17040243.
    10.3390/md17040243
  54. Barbosa, M.; Costa, F.; Monteiro, C.; Duarte, F.; Martins, M.C.L.; Gomes, P.. "Antimicrobial coatings prepared from Dhvar-5-click-grafted chitosan powders". Acta Biomaterialia 84 (2019): 242-256. http://www.scopus.com/inward/record.url?eid=2-s2.0-85058393291&partnerID=MN8TOARS.
    10.1016/j.actbio.2018.12.001
  55. Barros, D.; Parreira, P.; Furtado, J.; Ferreira-da-Silva, F.; Conde-Sousa, E.; García, A.J.; Martins, M.C.L.; Amaral, I.F.; Pêgo, A.P.. "An affinity-based approach to engineer laminin-presenting cell instructive microenvironments". Biomaterials 192 (2019): 601-611. http://www.scopus.com/inward/record.url?eid=2-s2.0-85059918479&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2018.10.039
  56. Seabra, C.L.; Nunes, C.; Brás, M.; Gomez-Lazaro, M.; Reis, C.A.; Gonçalves, I.C.; Reis, S.; Martins, M.C.L.. "Lipid nanoparticles to counteract gastric infection without affecting gut microbiota". European Journal of Pharmaceutics and Biopharmaceutics 127 (2018): 378-386. http://www.scopus.com/inward/record.url?eid=2-s2.0-85044023662&partnerID=MN8TOARS.
    10.1016/j.ejpb.2018.02.030
  57. Freitas, S.C.; Correa-Uribe, A.; Martins, M.C.L.; Pelaez-Vargas, A.. "Self-Assembled Monolayers for Dental Implants". International Journal of Dentistry 2018 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85042526850&partnerID=MN8TOARS.
    10.1155/2018/4395460
  58. Cimino, M.; Gonçalves, R.M.; Bauman, E.; Barroso-Vilares, M.; Logarinho, E.; Barrias, C.C.; Martins, M.C.L.. "Optimization of the use of a pharmaceutical grade xeno-free medium for in vitro expansion of human mesenchymal stem/stromal cells". Journal of Tissue Engineering and Regenerative Medicine 12 3 (2018): e1785-e1795. http://www.scopus.com/inward/record.url?eid=2-s2.0-85038971432&partnerID=MN8TOARS.
    10.1002/term.2588
  59. Querido, M.M.; Felgueiras, H.P.; Rai, A.; Costa, F.; Monteiro, C.; Borges, I.; Oliveira, D.; Ferreira, L.; Martins, M.C.L.. "Cecropin–Melittin Functionalized Polyurethane Surfaces Prevent Staphylococcus epidermidis Adhesion without Inducing Platelet Adhesion and Activation". Advanced Materials Interfaces 5 24 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85055708783&partnerID=MN8TOARS.
    10.1002/admi.201801390
  60. Cimino, M.; Gonçalves, R.M.; Barrias, C.C.; Martins, M.C.L.. "Xeno-free strategies for safe human mesenchymal stem/stromal cell expansion: Supplements and coatings". Stem Cells International 2017 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85042597689&partnerID=MN8TOARS.
    10.1155/2017/6597815
  61. Parreira, P.; Soares, B.I.G.; Freire, C.S.R.; Silvestre, A.J.D.; Reis, C.A.; Martins, M.C.L.; Duarte, M.F.. "Eucalyptus spp. outer bark extracts inhibit Helicobacter pylori growth: in vitro studies". Industrial Crops and Products 105 (2017): 207-214. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019603764&partnerID=MN8TOARS.
    10.1016/j.indcrop.2017.05.012
  62. Barbosa, M.; Vale, N.; Costa, F.M.T.A.; Martins, M.C.L.; Gomes, P.. "Tethering antimicrobial peptides onto chitosan: Optimization of azide-alkyne “click” reaction conditions". Carbohydrate Polymers 165 (2017): 384-393. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013929503&partnerID=MN8TOARS.
    10.1016/j.carbpol.2017.02.050
  63. Felgueiras, H.P.; Wang, L.M.; Ren, K.F.; Querido, M.M.; Jin, Q.; Barbosa, M.A.; Ji, J.; Martins, M.C.L.. "Octadecyl Chains Immobilized onto Hyaluronic Acid Coatings by Thiol-ene “Click Chemistry” Increase the Surface Antimicrobial Properties and Prevent Platelet Adhesion and Activation to Polyurethane". ACS Applied Materials and Interfaces 9 9 (2017): 7979-7989. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014824553&partnerID=MN8TOARS.
    10.1021/acsami.6b16415
  64. Oliveira, M.I.; Pinto, M.L.; Gonçalves, R.M.; Martins, M.C.L.; Santos, S.G.; Barbosa, M.A.. "Adsorbed Fibrinogen stimulates TLR-4 on monocytes and induces BMP-2 expression". Acta Biomaterialia 49 (2017): 296-305. http://www.scopus.com/inward/record.url?eid=2-s2.0-85007016045&partnerID=MN8TOARS.
    10.1016/j.actbio.2016.11.034
  65. Chang, H.; Zhang, H.; Hu, M.; Chen, J.-Y.; Li, B.-C.; Ren, K.-F.; Martins, M.C.L.; Barbosa, M.A.; Ji, J.. "Stiffness of polyelectrolyte multilayer film influences endothelial function of endothelial cell monolayer". Colloids and Surfaces B: Biointerfaces 149 (2017): 379-387. http://www.scopus.com/inward/record.url?eid=2-s2.0-84995602574&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2016.11.012
  66. Seabra, C.L.; Nunes, C.; Gomez-Lazaro, M.; Correia, M.; Machado, J.C.; Gonçalves, I.C.; Reis, C.A.; Reis, S.; Martins, M.C.L.. "Docosahexaenoic acid loaded lipid nanoparticles with bactericidal activity against Helicobacter pylori". International Journal of Pharmaceutics 519 1-2 (2017): 128-137. http://www.scopus.com/inward/record.url?eid=2-s2.0-85010199517&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2017.01.014
  67. Costa, F.; Sousa, D.M.; Parreira, P.; Lamghari, M.; Gomes, P.; Martins, M.C.L.; F Costa; D M Sousa; M Lamghari; P Gomes; M. Cristina L. Martins. "N-acetylcysteine-functionalized coating avoids bacterial adhesion and biofilm formation". Scientific Reports 7 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85037721926&partnerID=MN8TOARS.
    10.1038/s41598-017-17310-4
  68. Chen, X.-C.; Ren, K.-F.; Lei, W.-X.; Zhang, J.-H.; Martins, M.C.L.; Barbosa, M.A.; Ji, J.. "Self-Healing Spongy Coating for Drug "cocktail" Delivery". ACS Applied Materials and Interfaces 8 7 (2016): 4309-4313. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962576520&partnerID=MN8TOARS.
    10.1021/acsami.5b11602
  69. Gonçalves, I.C.; Magalhães, A.; Costa, A.M.S.; Oliveira, J.R.; Henriques, P.C.; Gomes, P.; Reis, C.A.; Martins, M.C.L.. "Bacteria-targeted biomaterials: Glycan-coated microspheres to bind Helicobacter pylori". Acta Biomaterialia 33 (2016): 40-50. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959468144&partnerID=MN8TOARS.
    10.1016/j.actbio.2016.01.029
  70. Parreira, P.; Fátima Duarte, M.; Reis, C.A.; Martins, M.C.L.. "Helicobacter pylori infection: A brief overview on alternative natural treatments to conventional therapy". Critical Reviews in Microbiology 42 1 (2016): 94-105. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959561260&partnerID=MN8TOARS.
    10.3109/1040841X.2014.892055
  71. Coelho, L.; De Almeida, J.M.M.M.; Santos, J.L.; Da Silva Jorge, P.A.; Martins, M.C.L.; Viegas, D.; Queirós, R.B.. "Aptamer-based fiber sensor for thrombin detection". Journal of Biomedical Optics 21 8 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84983802428&partnerID=MN8TOARS.
    10.1117/1.JBO.21.8.087005
  72. Barbosa, Mariana; Martins, M.; Gomes, Paula. "Grafting Techniques towards Production of Peptide-Tethered Hydrogels, a Novel Class of Materials with Biomedical Interest". Gels 1 2 (2015): 194-218. http://dx.doi.org/10.3390/gels1020194.
    10.3390/gels1020194
  73. Almeida, M.T.; Mesquita, F.S.; Cruz, R.; Osório, H.; Custódio, R.; Brito, C.; Vingadassalom, D.; et al. "Src-dependent tyrosine phosphorylation of non-muscle myosin heavy chain-IIA restricts Listeria monocytogenes cellular infection". Journal of Biological Chemistry 290 13 (2015): 8383-8395. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925760833&partnerID=MN8TOARS.
    10.1074/jbc.M114.591313
  74. Costa, F.M.T.A.; Maia, S.R.; Gomes, P.A.C.; Martins, M.C.L.. "Dhvar5 antimicrobial peptide (AMP) chemoselective covalent immobilization results on higher antiadherence effect than simple physical adsorption". Biomaterials 52 1 (2015): 531-538. http://www.scopus.com/inward/record.url?eid=2-s2.0-84932632783&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2015.02.049
  75. Zhang, H.; Chang, H.; Wang, L.-M.; Ren, K.-F.; Martins, C.M.L.; Barbosa, M.A.; Ji, J.. "Effect of Polyelectrolyte Film Stiffness on Endothelial Cells during Endothelial-to-Mesenchymal Transition". Biomacromolecules 16 11 (2015): 3584-3593. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946761662&partnerID=MN8TOARS.
    10.1021/acs.biomac.5b01057
  76. Monteiro, C.; Pinheiro, M.; Fernandes, M.; Maia, S.; Seabra, C.L.; Ferreira-Da-Silva, F.; Reis, S.; Gomes, P.; Martins, M.C.L.. "A 17-mer Membrane-Active MSI-78 Derivative with Improved Selectivity toward Bacterial Cells". Molecular Pharmaceutics 12 8 (2015): 2904-2911. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938303316&partnerID=MN8TOARS.
    10.1021/acs.molpharmaceut.5b00113
  77. Wang, L.-M.; Chang, H.; Zhang, H.; Ren, K.-F.; Li, H.; Hu, M.; Li, B.-C.; et al. "Dynamic stiffness of polyelectrolyte multilayer films based on disulfide bonds for in situ control of cell adhesion". Journal of Materials Chemistry B 3 38 (2015): 7546-7553. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942426354&partnerID=MN8TOARS.
    10.1039/c5tb01151e
  78. Monteiro, C.; Fernandes, M.; Pinheiro, M.; Maia, S.; Seabra, C.L.; Ferreira-Da-Silva, F.; Costa, F.; et al. "Antimicrobial properties of membrane-active dodecapeptides derived from MSI-78". Biochimica et Biophysica Acta - Biomembranes 1848 5 (2015): 1139-1146. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923289681&partnerID=MN8TOARS.
    10.1016/j.bbamem.2015.02.001
  79. Lopes, D.; Nunes, C.; Martins, M.C.L.; Sarmento, B.; Reis, S.. "Eradication of Helicobacter pylori: Past, present and future". Journal of Controlled Release 189 (2014): 169-186. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904904149&partnerID=MN8TOARS.
    10.1016/j.jconrel.2014.06.020
  80. Gonçalves, I.C.; Henriques, P.C.; Seabra, C.L.; Martins, M.C.L.. "The potential utility of chitosan micro/nanoparticles in the treatment of gastric infection". Expert Review of Anti-Infective Therapy 12 8 (2014): 981-992. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904003586&partnerID=MN8TOARS.
    10.1586/14787210.2014.930663
  81. Costa, F.; Maia, S.; Gomes, J.; Gomes, P.; Martins, M.C.L.. "Characterization of hLF1-11 immobilization onto chitosan ultrathin films, and its effects on antimicrobial activity". Acta Biomaterialia 10 8 (2014): 3513-3521. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903724424&partnerID=MN8TOARS.
    10.1016/j.actbio.2014.02.028
  82. Freitas, S.C.; Maia, S.; Figueiredo, A.C.; Gomes, P.; Pereira, P.J.B.; Barbosa, M.A.; Martins, M.C.L.. "Selective albumin-binding surfaces modified with a thrombin-inhibiting peptide". Acta Biomaterialia 10 3 (2014): 1227-1237. http://www.scopus.com/inward/record.url?eid=2-s2.0-84895067841&partnerID=MN8TOARS.
    10.1016/j.actbio.2013.11.023
  83. Parreira, P.; Shi, Q.; Magalhaes, A.; Reis, C.A.; Bugaytsova, J.; Borén, T.; Leckband, D.; Martins, M.C.L.. "Atomic force microscopy measurements reveal multiple bonds between Helicobacter pylori blood group antigen binding adhesin and Lewis b ligand". Journal of the Royal Society Interface 11 101 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84921665680&partnerID=MN8TOARS.
    10.1098/rsif.2014.1040
  84. Nogueira, F.; Gonçalves, I.C.; Martins, M.C.L.. "Effect of gastric environment on Helicobacter pylori adhesion to a mucoadhesive polymer". Acta Biomaterialia 9 2 (2013): 5208-5215. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872069015&partnerID=MN8TOARS.
    10.1016/j.actbio.2012.09.011
  85. Gonçalves, I.C.; Magalhães, A.; Fernandes, M.; Rodrigues, I.V.; Reis, C.A.; Martins, M.C.L.. "Bacterial-binding chitosan microspheres for gastric infection treatment and prevention". Acta Biomaterialia 9 12 (2013): 9370-9378. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887160912&partnerID=MN8TOARS.
    10.1016/j.actbio.2013.07.034
  86. Parreira, P.; Magalhães, A.; Reis, C.A.; Borén, T.; Leckband, D.; Martins, M.C.L.. "Bioengineered surfaces promote specific protein-glycan mediated binding of the gastric pathogen Helicobacter pylori". Acta Biomaterialia 9 11 (2013): 8885-8893. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885052038&partnerID=MN8TOARS.
    10.1016/j.actbio.2013.06.042
  87. Fernandes, M.; Gonçalves, I.C.; Nardecchia, S.; Amaral, I.F.; Barbosa, M.A.; Martins, M.C.L.. "Modulation of stability and mucoadhesive properties of chitosan microspheres for therapeutic gastric application". International Journal of Pharmaceutics 454 1 (2013): 116-124. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884163785&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2013.06.068
  88. Santos, S.G.; Lamghari, M.; Almeida, C.R.; Oliveira, M.I.; Neves, N.; Ribeiro, A.C.; Barbosa, J.N.; et al. "Adsorbed fibrinogen leads to improved bone regeneration and correlates with differences in the systemic immune response". Acta Biomaterialia 9 7 (2013): 7209-7217. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878315890&partnerID=MN8TOARS.
    10.1016/j.actbio.2013.04.008
  89. Oliveira, J.R.; Martins, M.C.L.; Mafra, L.; Gomes, P.. "Synthesis of an O-alkynyl-chitosan and its chemoselective conjugation with a PEG-like amino-azide through click chemistry". Carbohydrate Polymers 87 1 (2012): 240-249. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054771159&partnerID=MN8TOARS.
    10.1016/j.carbpol.2011.07.043
  90. Martins, M.; Custod´io, R.; Camejo, A.; Almeida, M.T.; Cabanes, D.; Sousa, S.. "Listeria monocytogenes triggers the cell surface expression of Gp96 protein and interacts with its N terminus to support cellular infection". Journal of Biological Chemistry 287 51 (2012): 43083-43093. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871163192&partnerID=MN8TOARS.
    10.1074/jbc.M112.422568
  91. Freitas, S.C.; Cereija, T.B.; Figueiredo, A.C.; Osório, H.; Pereira, P.J.B.; Barbosa, M.A.; Martins, M.C.L.. "Bioengineered surfaces to improve the blood compatibility of biomaterials through direct thrombin inactivation". Acta Biomaterialia 8 11 (2012): 4101-4110. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873959808&partnerID=MN8TOARS.
    10.1016/j.actbio.2012.07.020
  92. Fischer, M.; Baptista, C.P.; Gonçalves, I.C.; Ratner, B.D.; Sperling, C.; Werner, C.; Martins, C.L.; Barbosa, M.A.. "The effect of octadecyl chain immobilization on the hemocompatibility of poly (2-hydroxyethyl methacrylate)". Biomaterials 33 31 (2012): 7677-7685. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865188580&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2012.07.007
  93. Gonçalves, I.; Fernandes, M.; Magalhães, A.; Reis, C.; Martins, C.. "Chitosan microspheres to prevent/remove helicobacter pylori gastric colonization". 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-84887004788&partnerID=MN8TOARS.
  94. Gonçalves, I.C.; Martins, M.C.L.; Barbosa, J.N.; Oliveira, P.; Barbosa, M.A.; Ratner, B.D.. "Platelet and leukocyte adhesion to albumin binding self-assembled monolayers". Journal of Materials Science: Materials in Medicine 22 9 (2011): 2053-2063. http://www.scopus.com/inward/record.url?eid=2-s2.0-80755133542&partnerID=MN8TOARS.
    10.1007/s10856-011-4381-9
  95. Martins, M.C.L.; Ochoa-Mendes, V.; Ferreira, G.; Barbosa, J.N.; Curtin, S.A.; Ratner, B.D.; Barbosa, M.A.. "Interactions of leukocytes and platelets with poly(lysine/leucine) immobilized on tetraethylene glycol-terminated self-assembled monolayers". Acta Biomaterialia 7 5 (2011): 1949-1955. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953868334&partnerID=MN8TOARS.
    10.1016/j.actbio.2011.01.013
  96. Parreira, P.; Magalhaes, A.; Gonaçalves, I.C.; Gomes, J.; Vidal, R.; Reis, C.A.; Leckband, D.E.; Martins, M.C.L.. "Effect of surface chemistry on bacterial adhesion, viability, and morphology". Journal of Biomedical Materials Research - Part A 99 A 3 (2011): 344-353. http://www.scopus.com/inward/record.url?eid=2-s2.0-80055008019&partnerID=MN8TOARS.
    10.1002/jbm.a.33178
  97. Costa, F.; Carvalho, I.F.; Montelaro, R.C.; Gomes, P.; Martins, M.C.L.. "Covalent immobilization of antimicrobial peptides (AMPs) onto biomaterial surfaces". Acta Biomaterialia 7 4 (2011): 1431-1440. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952187401&partnerID=MN8TOARS.
    10.1016/j.actbio.2010.11.005
  98. Gonçalves, R.; Martins, M.C.L.; Oliveira, M.J.; Almeida-Porada, G.; Barbosa, M.A.. "Bioactivity of immobilized EGF on self-assembled monolayers: Optimization of the immobilization process". Journal of Biomedical Materials Research - Part A 94 2 (2010): 576-585. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953815323&partnerID=MN8TOARS.
    10.1002/jbm.a.32723
  99. Oliveira, H.; Fernandez, R.; Pires, L.R.; Martins, M.C.L.; Simões, S.; Barbosa, M.A.; Pêgo, A.P.. "Targeted gene delivery into peripheral sensorial neurons mediated by self-assembled vectors composed of poly(ethylene imine) and tetanus toxin fragment c". Journal of Controlled Release 143 3 (2010): 350-358. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952239026&partnerID=MN8TOARS.
    10.1016/j.jconrel.2010.01.018
  100. Freitas, S.C.; Barbosa, M.A.; Martins, M.C.L.. "The effect of immobilization of thrombin inhibitors onto self-assembled monolayers on the adsorption and activity of thrombin". Biomaterials 31 14 (2010): 3772-3780. http://www.scopus.com/inward/record.url?eid=2-s2.0-77649271932&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2010.01.097
  101. Barbosa, J.N.; Martins, M.C.L.; Freitas, S.C.; Gonçalves, I.C.; Águas, A.P.; Barbosa, M.A.. "Adhesion of human leukocytes on mixtures of hydroxyl- and methyl-terminated self-assembled monolayers: Effect of blood protein adsorption". Journal of Biomedical Materials Research - Part A 93 1 (2010): 12-19. http://www.scopus.com/inward/record.url?eid=2-s2.0-77649225392&partnerID=MN8TOARS.
    10.1002/jbm.a.32480
  102. Oliveira, H.; Pires, L.R.; Fernandez, R.; Martins, M.C.L.; Simões, S.; Pêgo, A.P.. "Chitosan-based gene delivery vectors targeted to the peripheral nervous system". Journal of Biomedical Materials Research - Part A 95 3 A (2010): 801-810. http://www.scopus.com/inward/record.url?eid=2-s2.0-78249240032&partnerID=MN8TOARS.
    10.1002/jbm.a.32874
  103. Maciel, J.; Martins, M.C.L.; Barbosa, M.A.. "The stability of self-assembled monolayers with time and under biological conditions". Journal of Biomedical Materials Research - Part A 94 3 (2010): 833-843. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954806701&partnerID=MN8TOARS.
    10.1002/jbm.a.32746
  104. Carapeto, A.P.; Serro, A.P.; Nunes, B.M.F.; Martins, M.C.L.; Todorovic, S.; Duarte, M.T.; André, V.; Colaço, R.; Saramago, B.. "Characterization of two DLC coatings for joint prosthesis: The role of albumin on the tribological behavior". Surface and Coatings Technology 204 21-22 (2010): 3451-3458. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953715334&partnerID=MN8TOARS.
    10.1016/j.surfcoat.2010.04.022
  105. Martins, M.C.L.; Curtin, S.A.; Freitas, S.C.; Salgueiro, P.; Ratner, B.D.; Barbosa, M.A.. "Molecularly designed surfaces for blood deheparinization using an immobilized heparin-binding peptide". Journal of Biomedical Materials Research - Part A 88 1 (2009): 162-173. http://www.scopus.com/inward/record.url?eid=2-s2.0-57449118932&partnerID=MN8TOARS.
    10.1002/jbm.a.31849
  106. Gonçalves, R.M.; Martins, M.C.L.; Almeida-Porada, G.; Barbosa, M.A.. "Induction of notch signaling by immobilization of jagged-1 on self-assembled monolayers". Biomaterials 30 36 (2009): 6879-6887. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350188310&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2009.09.010
  107. Gonçalves, I.C.; Martins, M.C.L.; Barbosa, M.A.; Ratner, B.D.. "Protein adsorption and clotting time of pHEMA hydrogels modified with C18 ligands to adsorb albumin selectively and reversibly". Biomaterials 30 29 (2009): 5541-5551. http://www.scopus.com/inward/record.url?eid=2-s2.0-68549112719&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2009.06.025
  108. Gonçalves, I.C.; Martins, M.C.L.; Barbosa, M.A.; Naeemi, E.; Ratner, B.D.. "Selective protein adsorption modulates platelet adhesion and activation to oligo(ethylene glycol)-terminated self-assembled monolayers with C18 ligands". Journal of Biomedical Materials Research - Part A 89 3 (2009): 642-653. http://www.scopus.com/inward/record.url?eid=2-s2.0-66249128976&partnerID=MN8TOARS.
    10.1002/jbm.a.32011
  109. Barrias, C.C.; Martins, M.C.L.; Almeida-Porada, G.; Barbosa, M.A.; Granja, P.L.. "The correlation between the adsorption of adhesive proteins and cell behaviour on hydroxyl-methyl mixed self-assembled monolayers". Biomaterials 30 3 (2009): 307-316. http://www.scopus.com/inward/record.url?eid=2-s2.0-55249093830&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2008.09.048
  110. Gonçalves, I.C.; Martins, M.C.L.; Barbosa, M.A.; Naeemi, E.; Ratner, B.D.. "Platelet adhesion and activation modulated by selective adsorption of proteins to self-assembled monolayers". European Cells and Materials 14 SUPPL.3 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-84860903154&partnerID=MN8TOARS.
  111. Martins, M.C.L.; Curtin, S.A.; Freitas, S.C.; Salgueiro, P.; Ratner, B.D.; Barbosa, M.A.. "Engineering surfaces for blood deheparinization using an heparin-binding peptide". European Cells and Materials 14 SUPPL.3 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-84860897456&partnerID=MN8TOARS.
  112. Barrias, C.C.; Ribeiro, C.C.; Martins, M.C.L.; Barbosa, Mario A.; Rodrigues, D.; Sá Miranda, M.C.. "Calcium Phosphate Microspheres for Localised Delivery of a Therapeutic Enzyme". Key Engineering Materials 309-311 (2006): 903-906. http://dx.doi.org/10.4028/www.scientific.net/kem.309-311.903.
    10.4028/www.scientific.net/kem.309-311.903
  113. Rodrigues, S.N.; Gonçalves, I.C.; Martins, M.C.L.; Barbosa, M.A.; Ratner, B.D.. "Fibrinogen adsorption, platelet adhesion and activation on mixed hydroxyl-/methyl-terminated self-assembled monolayers". Biomaterials 27 31 (2006): 5357-5367. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746216936&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2006.06.010
  114. Serro, A.P.; Gispert, M.P.; Martins, M.C.L.; Brogueira, P.; Colaço, R.; Saramago, B.. "Adsorption of albumin on prosthetic materials: Implication for tribological behavior". Journal of Biomedical Materials Research - Part A 78 3 (2006): 581-589. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747426950&partnerID=MN8TOARS.
    10.1002/jbm.a.30754
  115. Carvalho, A.F.; Costa-Rodrigues, J.; Correia, I.; Costa Pessoa, J.; Faria, T.Q.; Martins, C.L.; Fransen, M.; Sá-Miranda, C.; Azevedo, J.E.. "The N-terminal half of the peroxisomal cycling receptor Pex5p is a natively unfolded domain". Journal of Molecular Biology 356 4 (2006): 864-875. http://www.scopus.com/inward/record.url?eid=2-s2.0-31344439778&partnerID=MN8TOARS.
    10.1016/j.jmb.2005.12.002
  116. Ferreira, L.; Evangelista, M.B.; Martins, M.C.L.; Granja, P.L.; Esteves, J.L.; Barbosa, M.A.. "Improving the adhesion of poly(ethylene terephthalate) fibers to poly(hydroxyethyl methacrylate) hydrogels by ozone treatment: Surface characterization and pull-out tests". Polymer 46 23 (2005): 9840-9850. http://www.scopus.com/inward/record.url?eid=2-s2.0-26844540116&partnerID=MN8TOARS.
    10.1016/j.polymer.2005.08.033
  117. Gonçalves, I.C.; Martins, M.C.L.; Barbosa, M.A.; Ratner, B.D.. "Protein adsorption on 18-alkyl chains immobilized on hydroxyl-terminated self-assembled monolayers". Biomaterials 26 18 (2005): 3891-3899. http://www.scopus.com/inward/record.url?eid=2-s2.0-11144307278&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2004.10.006
  118. Barrias, C.C.; Martins, M.C.L.; Miranda, M.C.S.; Barbosa, M.A.. "Adsorption of a therapeutic enzyme to self-assembled monolayers: Effect of surface chemistry and solution pH on the amount and activity of adsorbed enzyme". Biomaterials 26 15 (2005): 2695-2704. http://www.scopus.com/inward/record.url?eid=2-s2.0-10044251257&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2004.07.033
  119. Barbosa, M.A.; Martins, M.C.L.; Barbosa, J.N.. "Interactions of cells and proteins with molecularly designed surfaces". European Cells and Materials 7 SUPPL.1 (2004): http://www.scopus.com/inward/record.url?eid=2-s2.0-84860639031&partnerID=MN8TOARS.
  120. Martins, M.C.L.; Wang, D.; Ji, J.; Feng, L.; Barbosa, M.A.. "Albumin and fibrinogen adsorption on PU-PHEMA surfaces". Biomaterials 24 12 (2003): 2067-2076. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037400503&partnerID=MN8TOARS.
    10.1016/S0142-9612(03)00002-4
  121. Martins, Ma.C.L.; Naeemi, E.; Ratner, B.D.; Barbosa, M.A.. "Albumin adsorption on Cibacron Blue F3G-A immobilized onto oligo(ethylene glycol)-terminated self-assembled monolayers". Journal of Materials Science: Materials in Medicine 14 11 (2003): 945-954. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344629191&partnerID=MN8TOARS.
    10.1023/A:1026394431100
  122. Martins, M.C.L.; Ratner, B.D.; Barbosa, M.A.. "Protein adsorption on mixtures of hydroxyl- and methyl-terminated alkanethiols self-assembled monolayers". Journal of Biomedical Materials Research - Part A 67 1 (2003): 158-171. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344306504&partnerID=MN8TOARS.
  123. Martins, M.C.L.; Fonseca, C.; Barbosa, M.A.; Ratner, B.D.. "Albumin adsorption on alkanethiols self-assembled monolayers on gold electrodes studied by chronopotentiometry". Biomaterials 24 21 (2003): 3697-3706. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038802804&partnerID=MN8TOARS.
    10.1016/S0142-9612(03)00244-8
  124. Martins, M.C.L.; Wang, D.; Ji, J.; Feng, L.; Barbosa, M.A.. "Albumin and fibrinogen adsorption on Cibacron blue F3G-A immobilised onto PU-PHEMA (polyurethane-poly (hydroxyethylmethacrylate)) surfaces". Journal of Biomaterials Science, Polymer Edition 14 5 (2003): 439-455. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038316702&partnerID=MN8TOARS.
    10.1163/156856203766652057
Capítulo de livro
  1. Costa, F.; Teixeira, C.; Gomes, P.; Martins, M.C.L.. "Clinical application of AMPs". In Antimicrobial Peptides, Advances in Experimental Medicine and Biology, 281-298. Springer Singapore, 2019.
    Publicado • 10.1007/978-981-13-3588-4_15
  2. Leiro, V.; Parreira, P.; Freitas, S.C.; Martins, M.C.L.; Pêgo, A.P.. "Conjugation Chemistry Principles and Surface Functionalization of Nanomaterials". 35-66. 2018.
  3. Felgueiras, H.P.; Antunes, J.C.; Martins, M.C.L.; Barbosa, M.A.. "Fundamentals of protein and cell interactions in biomaterials". In Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair, editado por M. Cristina L. Martins; Mario A Barbosa, 1-27. Elsevier, 2018.
    10.1016/b978-0-08-100803-4.00001-2
  4. Parreira, Paula; Leal Seabra, Catarina; Lopes-de-Campos, Daniela; Cristina L. Martins, Maria. "Nonantibiotic-Based Therapeutics Targeting Helicobacter pylori: From Nature to the Lab". In Helicobacter pylori [Working Title]. IntechOpen, 2018.
    10.5772/intechopen.81248
  5. Costa, F.; Gomes, P.; Martins, M.C.L.. "Antimicrobial peptides (AMP) biomaterial coatings for tissue repair". In Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair, editado por M. Cristina L. Martins; Mario A. Barbosa, 329-345. Elsevier, 2017.
    10.1016/b978-0-08-100803-4.00013-9
  6. Lopes, Daniela; Nunes, Claudia; Martins, M. Cristina; Sarmento, Bruno; Reis, Salette. "Targeting strategies for the treatment of Helicobacter pylori infections". In Nano based drug delivery, 339-366. IAPC Publishing, 2015.
    10.5599/obp.8.13
  7. Martins, M. Cristina L.; Sousa, Susana R.; Antunes, Joana C.; Barbosa, Mário A.. "Protein Adsorption Characterization". In Nanotechnology in Regenerative Medicine, 141-161. Humana Press, 2011.
    10.1007/978-1-61779-388-2_10
  8. BARBOSA, M A; MARTINS, M C L; BARBOSA, J N. "Cellular response to the surface chemistry of nanostructured biomaterials". In Cellular Response to Biomaterials, 85-113. Elsevier, 2009.
    10.1533/9781845695477.1.85
  9. Martins, Maria. "Properties of soft materials (Appendix B).". In Biomaterials Science – An Introduction to Materials in Medicine, editado por Buddy D. Ratner / University of Washington, Seattle, USA; Allan Hoffman; Frederick Schoen; Jack Lemons. Elsevier Academic Press Inc., San Diego, CA, USA,, 2004.
    Publicado
  10. Martins, Maria. "Biomaterials". In Fundamentos e Aplicações da Biologia, editado por Nelson Lima,; Manuel Mota, 377-397. Lisboa, Portugal: LIDEL, 2003.
    Publicado • 10.1016/b978-0-08-087780-8.00077-2
  11. M. Cristina L. Martins. "1. Barbosa MA, Jian J, Granja PL, Martins CL. Engenharia de biomateriais à escala molecular. In: Materiais 2000 (Ferreira PJ and Fortes A, editors). Lisbon, Portugal: IST Press; p. 391-399. 2003.". 2000.
Livro
  1. Barbosa, M.A.; Martins, M.C.L.; Martins, Maria. Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair. Elsevier. 2017.
    Publicado • 10.1016/C2015-0-01811-1
  2. Barrias, C.C.; Ribeiro, C.C.; Martins, M.C.L.; Barbosa, M.A.; Rodrigues, D.; Miranda, M.C.S.. Calcium phosphate microspheres for localised delivery of a therapeutic enzyme. 2006.
Poster em conferência
  1. Fonseca, Diana R.; Francesca Annis; Ana Moura; Seabra, Catarina Leal; Victoria Leiro; Berta N. Estevinho; Cátia Teixeira; et al. "Beyond antibiotics: Pexiganan A-grafted microspheres to clear H. pylori infection". Trabalho apresentado em 3rd BioIberoamerica 2022, 2022.
  2. Pedro Alves; Ruben Pereira; Natália Fagundes; Cátia Teixeira; Barrias, Cristina; Paula Gomes; Fabíola Costa; M Cristina L Martins. "Antimicrobial peptide immobilization opens the door for improved chitosan-based dressings for chronic infected wounds". Trabalho apresentado em 6th TERMIS World Congress, 2021.
  3. Pedro Alves; Fonseca, Diana R.; Berta Nogueiro Estevinho; Cátia Teixeira; Gomes, Paula; Barrias, Cristina; M. Cristina L. Martins. "‘Wound’n’t it be nice? Spray-dried chitosan microspheres functionalized with antimicrobial peptides to fight infection in chronic wounds". Trabalho apresentado em 4th PhDay – Break borders, build opportunities, 2021.
  4. Fonseca, Diana R.; NETO, ESTRELA; Custódio, Beatriz; Sofia Guimarães; Paulo Freitas; Parreira, Paula; M. Cristina L. Martins. "Chitosan nanoparticles as a powerful biomaterial to kill Helicobacter pylori". Trabalho apresentado em 4th PhDay – Break borders, build opportunities, 2021.
  5. Sandra Gomes; Rute Chitas; Cláudia Nunes; Oliveira, Joaquim Miguel; Reis, Rui L.; M. Cristina L. Martins; Parreira, Paula. "Nanostructured Lipid Carriers performance against Helicobacter pylori by developing a pH-responsive system". Trabalho apresentado em 31st Conference of the European Society for Biomaterials, 2021.
  6. António Ramoa; Luis Moreira; Cátia Teixeira; Leiro, Victoria; Paula Gomes; José das Neves; M. Cristina L. Martins; Claudia Monteiro. "AMP-grafted PLGA-PEG Nanoparticles to Fight Bacterial Wound Infections". Trabalho apresentado em 31st Conference of the European Society for Biomaterials, 2021.
  7. "B. Ribeiro; R. Offoiach; Monteiro, Claudia; E. Salatin; Martins, M.C.L.; A. P. Pego; L. Fedrizzi; M. Lekka . Antibacterial effect of Ti6Al4V modified with Zn- incorporated or Cu-incorporated TiO2 nanotube arrays". Trabalho apresentado em 31st Conference of the European Society for Biomaterials, 2021.
  8. Fonseca, Diana R.; Ana Moura; Seabra, Catarina Leal; Sandra Gomes; Joaquim M Oliveira; Reis, Rui L.; Leiro, Victoria; et al. "Gellan Gum hydrogels as a pH-responsive system to control the gastric delivery of highly effective antimicrobial microspheres against Helicobacter pylori". Trabalho apresentado em 34th Workshop of the European Helicobacter and Microbiota Study Group, 2021.
  9. Pedro Alves; Ruben Pereira; Beatriz Costa; Natália Tassi; Cátia Teixeira; Leiro, Victoria; Paula Gomes; Fabiola Costa; M. Cristina L. Martins. "When dialysis gets ‘mesh’y: removal of adsorbed peptide from high molecular weight chitosan to yield a contact-killing biomaterial". Trabalho apresentado em Doctoral Congress in Engineering 2021, 2021.
  10. Fonseca, Diana R.; Ana Moura; Seabra, Catarina Leal; Leiro, Victoria; Berta N. Estevinho; Cátia Teixeira; Gomes, Paula; Parreira, Paula; M. Cristina L. Martins. "When Helicobacter pylori met pexiganan A-grafted chitosan microspheres: a fateful story". Trabalho apresentado em Doctoral Congress in Engineering 2021, 2021.
  11. Fonseca, Diana R.; Ana Moura; Seabra, Catarina Leal; Leiro, Victoria; Cátia Teixeira; Paula Gomes; Parreira, Paula; M. Cristina L. Martins. "Pexiganan A-grafted chitosan microspheres as the gastric infection management future". Trabalho apresentado em EuroNanoForum 2021, 2021.
  12. Pedro M. Alves; Rúben F. Pereira; B Costa; Natália Fagundes; Cátia teixeira; Paula Gomes; Fabíola Costa; M. Cristina L. Martins. "Efficient antimicrobial peptide tethering onto chitosan via thiol-norbornene photoclick chemistry". Trabalho apresentado em 11th World Biomaterials Congress 2020, 2020.
  13. Andreia Pereira; K. Schneider; S Melo; C. Grasl; M. Cristina L. Martins; H. Bergmeister; Inês C. Gonçalves. "Graphene-reinforced decellularized vessels as cell-free scaffolds for vascular applications". Trabalho apresentado em 11th World Biomaterials Congress 2020, 2020.
  14. Rute Chitas; Catarina Seabra; Cláudia Nunes; Paula Parreira; M. Cristina L. Martins. "Optimization of drug-free nanostructured lipid carriers (NLC) for Helicobacter pylori eradication". Trabalho apresentado em NanoPT 2020, 2020.
  15. Diana R Fonseca; Ana Moura; Catarina Seabra; Victoria Leiro; Berta N. Estevinho; Cátia Teixeira; Paula Gomes; Paula Parreira; M. Cristina L. Martins. "A deadly hug: chitosan microspheres functionalized with MSI-78A antimicrobial peptide kill Helicobacter pylori". Trabalho apresentado em 33rd Workshop of the European Helicobacter and Microbiota Study Group (online), 2020.
  16. Rute Chitas; Catarina Seabra; Claudia Nunes; Paula Parreira; M. Cristina L. Martins. "Counteracting Helicobacter pylori using drug-free nanostructured lipid carriers (NLC).". Trabalho apresentado em 33rd Workshop of the European Helicobacter and Microbiota Study Group (online), 2020.
  17. B Costa; R Mota; P. Parreira ; M. Cristina L. Martins; P Tamagnini; F Costa. "A new strategy to fight catheter associated urinary tract infections using a natural polymer-based coating". Trabalho apresentado em 2nd Portuguese Symposium on Research and Innovations in Urology, 2019.
  18. B Costa; J Cardoso; R Mota; P. Parreira ; P Tamagnini; M. Cristina L. Martins; F Costa. "Broad-spectrum anti-adhesive coating based on a natural marine polymer". Trabalho apresentado em 30th Annual Conference of the European Society for Biomaterials, 2019.
  19. B Costa; R Mota; P. Parreira ; P Tamagnini; M. Cristina L. Martins; F Costa. "Natural Broad-Spectrum Anti-adhesive Coating". Trabalho apresentado em IV Encontro de Biotecnologia Medicinal, 2019.
  20. C Monteiro; F Costa; A M Pirttilä; A M Tejesvi; M. Cristina L. Martins. "Antimicrobial activity of a de novo designed AMP derived from crowberry endophyte after surface covalent immobilization". Trabalho apresentado em IMAP 2019, 9th International Meeting on Antimicrobial Peptides, 2019.
  21. P. Parreira ; C Monteiro; V Graça; J Gomes; P Gomes; I C Gonçalves; M. Cristina L. Martins. "Nanostructured surfaces with high bactericidal effect against Helicobacter pylori". Trabalho apresentado em 29th Annual Conference of the European Society for Biomaterials (ESB 2018), 2018.
  22. F Costa; D A Sousa; P. Parreira ; M Lamghari; P Gomes; M. Cristina L. Martins. "Surface immobilized N-acetyl cysteine avoids bacteria adhesion without preventing cell adhesion and proliferation". Trabalho apresentado em 29th Annual Conference of the European Society for Biomaterials (ESB 2018), 2018.
  23. D Lopes; R M Pinto; S Lima; B Sarmento; M. Cristina L. Martins; C Nunes; S Reis. "Amoxicillin-loaded lipid nanoparticles: towards a therapeutic approach for Helicobacter pylori infections". Trabalho apresentado em NanoBio&Med2017, 2017.
  24. I F Cruz; M T Costa; P. Parreira ; C Pereira; M. Cristina L. Martins; A M Pereira. "Chitosan-coated magnetic nanoparticles as a tool to fight Helicobacter pylori". Trabalho apresentado em E-MRS Fall Meeting, 2017.
  25. M Barbosa; C Monteiro; F Costa; M. Cristina L. Martins; P Gomes. "Tethering of Dhvar5 onto a clickable chitosan derivative for the synthesis of antimicrobial peptide-based coatings". Trabalho apresentado em 28th Annual Conference of the European Society for Biomaterials (ESB 2017), 2017.
  26. P. Parreira ; C Monteiro; V Graça; J Gomes; P Gomes; I C Gonçalves; M. Cristina L. Martins. "Immobilization of an antimicrobial peptide with antibacterial effect against Helicobacter pylori". Trabalho apresentado em 6th China-Europe Symposium on Biomaterials in Regenerative Medicine-CESB2017, 2017.
  27. M Barbosa; C Monteiro; F Costa; M. Cristina L. Martins; P Gomes. "Unravelling the azide-alkyne “click” chemistry concept: a promising strategy for the development of antimicrobial peptide-based coatings". Trabalho apresentado em 6th China-Europe Symposium on Biomaterials in Regenerative Medicine-CESB2017, 2017.
  28. A T Pereira; H Bergmeister; C Grasl; M. Cristina L. Martins; F D Magalhães; I C Gonçalves. "Composites of Polymers/carbon nano-fillers for blood contact applications". Trabalho apresentado em 6th China-Europe Symposium on Biomaterials in Regenerative Medicine-CESB2017, 2017.
  29. F Costa; D M Sousa; M Lamghari; P Gomes; M. Cristina L. Martins. "Effect of surface immobilized N-acetylcysteine on bacteria and cell adhesion". Trabalho apresentado em 6th China-Europe Symposium on Biomaterials in Regenerative Medicine-CESB2017, 2017.
  30. A T Pereira; P C Henriques; A M Pinto; M. Cristina L. Martins; F D Magalhães; I C Gonçalves. "Polymers loaded with carbon nano-fillers for blood contact applications". Trabalho apresentado em Graphene, 2017.
  31. A T Pereira; H Bergmeister; C Grasl; M. Cristina L. Martins; F D Magalhães; I C Gonçalves. "Carbon nano-fillers loaded polymers for blood contact applications". Trabalho apresentado em II Jornadas Nacionais de Caracterização de Materiais, 2017.
  32. C L Seabra CL; C Nunes; Gomez-Lazaro; M Correia; J C Machado; I C Gonçalves; C A Reis; S Reis; M. Cristina L. Martins. "Effect of docosahexaenoic acid loaded nanoparticles on the growth of Helicobacter pylori in vitro". Trabalho apresentado em BioImaging 2016 – 5th International Symposium in Applied Bioimaging: Disease in Focus, 2016.
  33. P C Henriques; L M Costa; C Seabra; S Junqueira-Neto;; R Carvalho; B Antunes; A Magalhães; C Reis; F Gartner; E Touati; J Gomes; M. Cristina L. Martins; I C Gonçalves. "Bacteria-binding microspheres to fight Helicobacter pylori gastric infection". Trabalho apresentado em BioImaging 2016 – 5th International Symposium in Applied Bioimaging: Disease in Focus, 2016.
  34. C L Seabra; C Nunes; C A Reis; I C Gonçalves; S Reis; M. Cristina L. Martins. "Anti-Helicobacter pylori activity of lipid nanoparticles loaded with an omega-3 polyunsaturated fatty acid". Trabalho apresentado em XXIXth International Workshop on Helicobacter & Microbiota in Inflammation and Cancer, 2016.
  35. P C Henriques; L M Costa; C Seabra; S Junqueira-Neto; R Carvalho, B Antunes; A Magalhães; C Reis; F Gartner; E Touati; J Gomes; M. Cristina L. Martins; I C Gonçalves. "Bacteria-binding microspheres to fight Helicobacter pylori gastric infection". Trabalho apresentado em XXIXth International Workshop on Helicobacter & Microbiota in Inflammation and Cancer, 2016.
  36. D Oliveira; N Vale; P Gomes; M. Cristina L. Martins; C Monteiro. "MSI-78 (4-20) immobilization on chitosan ultrathin films and its antimicrobial properties". Trabalho apresentado em 6th Thesingle Biofilm Conference, 2016.
  37. F Costa; M Barbosa; P Gomes; M. Cristina L. Martins. "Antimicrobial peptide (Dhvar5) covalent immobilization parameters influence antimicrobial activity of the coating". Trabalho apresentado em 34th European Peptide Symposium and the 8th International Peptide Symposium, 2016.
  38. D Oliveira; N Vale; P Gomes; M. Cristina L. Martins; C Monteiro; D Oliveira; N Vale; P Gomes. "Antimicrobial coating based on MSI-78 (4-20) immobilization on chitosan ultrathin films". Trabalho apresentado em 34th European Peptide Symposium and the 8th International Peptide Symposium, 2016.
  39. M Querido, A Rai; A P Felgueiras; L Ferreira; M. Cristina L. Martins. "Influence of Cecropin-Melittin antimicrobial coating in platelet adhesion/activation to biomaterials". Trabalho apresentado em VI International Conference on Antimicrobial Research (ICAR 2016), 2016.
  40. M Querido; A Rai; H P Felgueiras; L Ferreira; M. Cristina L. Martins. "Influence of Cecropin-Melittin antimicrobial coating in platelet adhesion/activation to biomaterials". Trabalho apresentado em 7th Symposium on Bioengineering- Faculdade de Engenharia da Universidade do Porto, 2016.
  41. C Monteiro; F Fernandes; M Pinheiro; M Maia; C Seabra; F Ferreira da Silva; F Costa; S Reis; P Gomes; M. Cristina L. Martins. "A 17-mer membrane-active MSI-78 derivative with improved selectivity towards bacterial cells". Trabalho apresentado em 27th European Conference on Biomaterials, 2015.
  42. M. Cristina L. Martins; M Cimino; E Bauman; R M Gonçalves; F Belda; C C Barrias. "Human Mesenchymal Stem Cells expansion under xeno-free conditions for regenerative therapies". Trabalho apresentado em 27th European Conference on Biomaterials, 2015.
  43. M. Cristina L. Martins; F Costa; S Maia; P Gomes. "Antimicrobial Peptide Immobilization for the development of an antibacterial coating". Trabalho apresentado em The eCM XVI Congress, 2015.
Tese / Dissertação
  1. M. Cristina L. Martins. "Interaction between Blood Proteins and Surfaces: Self-Assembled Monolayers (SAMs) and Biomedical Polymers". Doutoramento, Universidade do Porto Faculdade de Engenharia, 2003.

Propriedade Intelectual

Patente
  1. M. Cristina L. Martins. 2018. "Rita Matos, Fabiola Costa, Paula Tamagnini and Martins MCL. USES OF CYANOBACTERIUM EXTRACELLULAR POLYMER, COMPOSITIONS, COATED SURFACES OR ARTICLES. (PCT/IB2019/051904 with priority date: 08.03.2018)".
    Concedida/Emitida
  2. M. Cristina L. Martins. 2018. "Seabra CL; Nunes C, Reis S, Martins MCL. NANOSTRUCTURATED LIPID CARRIERS, METHODS AND USES THEREOF. WO2018002853 (with priority date: 2016.06.28)".
    Concedida/Emitida
  3. M. Cristina L. Martins. 2013. "Martins MCL, Gonçalves IC, Gomes P, Oliveira JR, Reis AC, Magalhães A. Microspheres for treating helicobacter pylori infections. WO 2013164652 A3 (2013-11-07)".
Pedido provisório de patente
  1. 2024. "Martins MCL, Parreira P, Pinho AS, Fonseca D, Pereira R. Sterols for use in the management of Helicobacter sp".
    Protegido
  2. 2022. "Martins MCL, Parreira P, Chitas R, Albumin interaction with Helicobacter spp. (PPP 20222004283212 / with priority date: 07.12.2022)".
    Protegido
  3. 2022. "Martins MCL, Pereira R, Parreira P, Ferreira L, Rai A, Pereira M, CHOLESTEROL/ETHYLENE GLYCOL GOLD NANOPARTICULES FOR TREATMENT OF HELICOBACTER PYLORI INFECTION ((PPP 20222004188852 / with priority date: 11.11.2022)".
  4. 2022. "Martins MCL, Monteiro C, Pereira A, Rocha M, Batista I. MAGNETIC NANOPARTICLE DELIVERY SYSTEM (PPP 20221000002945 / with priority date: 29.07.2022)".
    Protegido
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/09/15 Bioengineered biomaterial coatings based on antimicrobial peptides to fight bacterial infections (Keynote) 8th China-Europe Symposium on Biomaterials in Regenerative Medicine (CESB 2024).
(Nuremberg, Alemanha)
2024/09/12 The potential utility of chitosan micro/nanoparticles in the treatment of gastric infection (Keynote) 37th Workshop of the European Helicobacter and Microbiota Study Group (EHMSG 2024).
European Helicobacter and Microbiota Study Group (Porto, Portugal)
2024/05/26 Multifunctional biomaterials for blood contacting and cardiovascular applications (Keynote) 12th World Biomaterials Congress (WBC 2024).
THE KOREAN SOCIETY FOR BIOMATERIALS (Daegu, Coreia do Sul)
2022/04 Nanostructured lipid carriers (NLC) against Helicobacter pylori: A nano approach to fight a big problem 3rd BioIberoamerica 2022
2021/09 Breaking the barrier: N-acetyl-cysteine- loaded nanoparticles as a strategy to disrupt bacterial biofilms 31st Conference of the European Society for Biomaterials
2021/09 The quest for survival in the highly proteolytic environment of a skin chronic wound: a case for efficient antimicrobial peptide conjugation 31st Conference of the European Society for Biomaterials
2021/09 Pexiganan-A grafted chitosan microparticles & Helicobacter pylori: a bitter love story 31st Conference of the European Society for Biomaterials (Online). September 2021
2021/05 Improving Nanostructured Lipid Carriers activity against Helicobacter pylori: development of pH-responsive systems for gastric settings 14.º Encontro de Jovens Investigadores da U.PORTO
(Portugal)
2021/05 AMP-PLGA nanoparticles to fight bacterial wound infections 14.º Encontro de Jovens Investigadores da U.PORTO
2021/03 The bittersweet symphony of Pexiganan-A grafted chitosan microparticles & Helicobacter pylori ANNIC- Applied Nanotechnology and Nanoscience International Conference (online)
2021/03 Fighting Helicobacter pylori with drug-free nanostructured lipid carriers (NLC) ANNIC- Applied Nanotechnology and Nanoscience International Conference (online)
2021/03 AMP-PLGA nanoparticles to fight bacterial wound infections XII Symposium on Bioengineering
2020/12 Graphene oxide-reinforced poly(2-hydroxyethyl methacrylate) hydrogels with extreme stiffness and high-strength Advanced Materials Conference (online)
2020/12 Antibiotic-Free Chitosan Microparticles for Helicobacter pylori infection management. 11th World Biomaterials Conference (online)
2020/10 Fatal attraction: chitosan microspheres decorated with MSI-78A kill Helicobacter pylori NanoPT 2020 (online)
2020/06 Surface Grafted MSI-78A antimicrobial peptide has high potential for gastric infection management BioNano Innovation 2020 (online)
2020 Impact of surface conjugation on the bactericidal activity of antimicrobial peptides (Keynote) 17th Iberian Peptide Meeting
(Madrid, Spain)
2020 Reduction in viable surface-adhered bacteria promoted by efficient conjugation of antimicrobial peptide (Dhvar5) onto chitosan EUGLOH Annual Student Research Conference 2020
2019 Antimicrobial Coatings to Prevent Biomaterials-Associated Infection V Semana de Bioengenharia - IST- Instituto Superior Tecnico
(Lisboa, Portugal)
2019 Antibiotic-free Lipid Nanoparticles for Gastric Infection Management XXXIInd International Workshop on Helicobacter and Microbiota in Inflammation and Cancer
(Austria)
2019 NanoPyl: smart and “friendly” antibiotic-free lipid nanoparticles for gastric infection management NanoMed Europe (Nanomedicine; European Technology Platform on Nanomedicine – ETPN Association)
(Braga, Portugal)
2018 AntiMicrobial Peptide (AMP)-chitosan coatings to avoid biomaterials-associated infection: influence of AMP characteristics and immobilization strategy. Advanced Materials and Surfaces for Tissue Replacement and Regeneration in Health (Keynote) XVII Brazilian MRS Meeting
(Natal-RN, Brazil)
2018 Biofunctional coatings for cardiovascular interventional devices. The 3nd Sino-Portugal Advanced Materials Innovation Forum, Hangzhou, China (Invited Speaker) 3nd Sino-Portugal Advanced Materials Innovation Forum
(Hangzhou, China)
2018 Biomaterial Coatings to Fight Infection. (Invited) ‘Tissue Engineering’ School of Medical Science and Technology
(Kharagpur, India)
2018 Bioengineered Strategies to fight gastric infection Cancer Seminars. i3S-Instituto de investigação e Inovação em Saude
(Porto, Portugal)
2018 Aplicação da nanotecnologia no tratamento específico da infecção por Helicobacter pylori Conferências em Oncobiologia 2018
(Porto, Portugal)
2018 Lipid-based nanoparticles that counteract gastric infection without affecting gut microbiota. BioMedEng18 conference
(Imperial College London, UK)
2018 Lipid-based nanoparticles that counteract gastric infection burden 29th Annual Conference of the European Society for Biomaterials (ESB 2018)
(Maastricht, Netherlands)
2018 Bactericidal nanostructured surfaces with high impact against Helicobacter pylori NanoPT2018- NanoPortugal International conference
(Lisboa, Portugal)
2017 N-acetyl cysteine functionalized chitosan film avoids bacteria adhesion without preventing cell adhesion and proliferation AMBA 2017: Advanced Materials for Biomedical Applications
(Ghent, Belgium)
2017 Antimicrobial activity of MSI-78 (4-20) immobilized on chitosan ultrathin films 28th Annual Conference of the European Society for Biomaterials (ESB 2017)
(Athens, Greece)
2017 Docosahexaenoic acid loaded nanoparticles to fight Helicobacter pylori infection 28th Annual Conference of the European Society for Biomaterials (ESB 2017)
(Athens, Greece)
2017 Octadecyl chains immobilized onto hyaluronic acid coatings by thiol-ene "click chemistry" increase the surface antimicrobial properties and prevent platelet adhesion and activation to polyurethane 28th Annual Conference of the European Society for Biomaterials (ESB 2017)
(Athens, Greece)
2017 Nanodelivery system to fight Helicobacter pylori gastric infection 6th China-Europe Symposium on Biomaterials in Regenerative Medicine-CESB2017
(Porto, Portugal)
2017 Octadecyl chains immobilized onto hyaluronic acid coatings by thiol-ene "click chemistry" increase the surface antimicrobial properties and prevent platelet adhesion and activation to polyurethane 6th China-Europe Symposium on Biomaterials in Regenerative Medicine-CESB2017
(Porto, Portugal)
2017 Immobilization of Cecropin-melittin antimicrobial peptide onto polyurethane to prevent infections without inducing thrombus formation 6th China-Europe Symposium on Biomaterials in Regenerative Medicine-CESB2017
(Porto, Portugal)
2016 Biomaterial Coatings for cardiovascular interventional devices 2nd Sino-Portuguese Advanced Materials Innovation Forum
(Aveiro, Portugal)
2016 Nanostructured Biomaterials to Fight Infection i3S-Instituto de investigação e Inovação em Saude
(Porto, Portugal)
2016 Development of biomaterials for the treatment of Helicobacter pylori gastric infection Bionanosystems for pharmaceutical and cosmetic applications
(Braga, Portugal)
2016 A Surface to attach to... II Semana de Bioengenharia, IST- Instituto Superior Tecnico
(Lisboa, Portugal)
2016 Bioengineered biomaterials to fight Helicobacter pylori infection and prevent gastric cancer Nano World Cancer Day
(Braga, Portugal)
2016 Anti-Helicobacter pylori activity of docosahexaenoic acid loaded nanostructured lipid carrier MAD-Nano2016
(Madeira Island, Portugal)
2016 The effect of covalent immobilization on the antibacterial activity of an Antimicrobial peptide (Dhvar5) VI International Conference on Antimicrobial Research (ICAR 2016)
(Torremolinos-Malaga, Spain)
2016 The antibactericidal effect of docosahexaenoic acid-loaded nanostructured lipid carriers against Helicobacter pylori VI International Conference on Antimicrobial Research (ICAR 2016)
(Torremolinos-Malaga, Spain)
2016 Chitosan microspheres can fight Helicobacter pylori gastric infection in mice 10th World Congress of Biomaterials
(Montreal, Canada)
2015 NanoBiomaterials to control infection and thrombus formation Portugal-China Biomaterials Seminar
(Hangzhou, China)
2015 Bioengineered Surfaces to Fight Gastric Infection 4º Encontro de Biotecnologia Microbiana e Farmacêutica
(Porto, Portugal)
2015 Mesa redonda: O segredo do Sucesso Profissional. Jornadas de Biotecnologia - Escola Superior de Biotecnologia. Universidade Católica Portuguesa
(Porto, Portugal)
2015 Helicobacter pylori-Binding Small Chitosan Microparticles that Penetrate Gastric Mucosa 27th European Conference on Biomaterials
(Krakow, Poland)
2015 Impact of different immobilization parameters on Dhvar5 antibacterial activity 3rd Stevens Conference on Bacteria-Material Interactions
(Hoboken, New Jersey, USA)
2015 Antimicrobial properties of short membrane-active peptides derived from MSI-78 5th China-Europe Symposium on Biomaterials in Regenerative Medicine
(Hangzhou, China)
2015 Fibrinogen-modified chitosan as an immunomodulatory biomaterial 5th China-Europe Symposium on Biomaterials in Regenerative Medicine
(Hangzhou, China)
2014 Anti-thrombogenic and anti-infective biomaterial coatings 1st Sino-Portugal Advanced Materials Innovation Forum
(Hangzhou, China)
2014 Anti-infective coatings based on covalent immobilization of antimicrobial peptides (AMPs) XIV Iberian Peptide (EPI) Meeting
(Bilbao, Spain)
2014 Bioengineered surfaces to fight infection i3s 4th Annual Meeting
(Povoa do Varzim, Portugal)
2014 Characterization of Membrane-active antimicrobial peptide derived from MSI-78 Antibiotic Alternatives for the New Millennium
(London, UK)
2014 Antimicrobial properties of membrane-active dodecapeptides derived from MSI-78 ICAR – International Conference on Antimicrobial Research
(Madrid, Spain)
2014 Helicobacter pylori-targeted biomaterials to prevent gastric cancer ICAR – International Conference on Antimicrobial Research
(Madrid, Spain)
2014 Characterization of hLF1-11 immobilization onto chitosan ultrathin films, and its effects on antimicrobial activity ICAR – International Conference on Antimicrobial Research
(Madrid, Spain)
2014 Nanoengineered biomaterials to fight gastric infection: exploring the glycan-adhesin specific interaction 26th European Conference on Biomaterials
(Liverpool, UK)
2013 Fibrinogen adsorption improved bone regeneration and correlated with differences in the systemic immune response 25th European Conference on Biomaterials
(Madrid, Spain)
2013 How sugars can make chitosan microspheres H. pylori specific 25th European Conference on Biomaterials
(Madrid, Spain)
2013 Immobilization of an Antimicrobial Peptide – Dhvar5 – for the development of an antibacterial coating 25th European Conference on Biomaterials
(Madrid, Spain)
2013 Engineered biomaterials to prevent/treat gastric infection CESB2013 - China Europe Symposium on Biomaterials in Regenerative Medicine
(Sorrento, Italy)
2013 Bacterial-Binding Chitosan Microspheres for Gastric Infection Treatment and Prevention EUCHIS 2013 - International Conference of the European Chitin Society
(Porto, Portugal)
2012 Tethering of a synthetic antimicrobial peptide for the development of an antimicrobial coating II International Conference on Antimicrobial Research (ICAR 2012)
(Lisboa, Portugal)
2012 Bioengineered surfaces designed to promote Helicobacter pylori adhesion via adhesin-carbohydrate specific recognition II International Conference on Antimicrobial Research (ICAR 2012)
(Lisboa, Portugal)
2012 Chitosan microspheres for Helicobacter pylori infection treatment and prevention of gastric colonization II International Conference on Antimicrobial Research (ICAR 2012)
(Lisboa, Portugal)
2011 Engineering surfaces to modulate biological responses Nanotechnology and Nanomedicine course
(Braga, Portugal)
2011 Engineering surfaces to trigger Helicobacter pylori adhesion 24th European Conference on Biomaterials
(Dublin, Ireland)
2011 Chitosan Microspheres to Prevent/Remove Helicobacter pylori Gastric Colonization 24th European Conference on Biomaterials
(Dublin, Ireland)
2010 BioEngineered Surfaces for Specific Biological Responses XI Jornadas de Biologia Aplicada
(Braga, Portugal)
2010 Macrophage Adhesion to CH3-, OH- and EG4-terminated Self-Assembled Monolayers: influence of serum proteins and adsorbed fibronectin 23rd European Conference on Biomaterials
(Tampere, Finland)
2009 Self-Assembled Monolayers (SAMs) 10th Advanced Summer Course in Cell-Materials Interactions: Self-assembly: from nature to clinics. / Biological Applications of Self-Assembled Monolayers
(Porto, Portugal)
2009 The role of protein adsorption in the cells/biomaterials interactions Atelier de Formation 194 (Inserm) Tissue engineering: study of the interfaces cell/tissue/material
(Saint-Raphael, France)
2009 Platelet and Leukocyte Adhesion to Albumin Binding Surfaces 2nd Chinese-European Symposium on Biomaterials in Regenerative Medicine
(Barcelona, Spain)
2009 Binding Albumin to Improve Hemocompatibility: from Model Surfaces to Real-World Polymers 22nd European Conference on Biomaterials
(Lausane, CH)
2009 Engineering Notch Signaling at the Nanoscale 22nd European Conference on Biomaterials
(Lausane, CH)
2008 Interacções Biológicas com Superfícies Nanoestruturadas Encontro Ciência em Portugal; Ciência 2008,, Fundação Calouste Gulbenkian
(Lisboa, Portugal)
2008 Nanostructured Surfaces: From Blood Contact Materials to Helicobacter pylori Workshop on Infection @ IBMC.INEB.IPATIMUP joint Workshops
(Porto, Portugal)
2008 Molecularly Designed Surfaces for Blood Deheparinization SIBB BioBCN2008, 3rd Iberian Biomaterials Congress
(Barcelona, Spain)
2008 Adhesion of Human Leukocytes on Mixtures of Hydroxyl- and Methyl-Terminated Self-Assembled Monolayers SIBB BioBCN2008, 3rd Iberian Biomaterials Congress
(Barcelona, Spain)
2008 Adsorption of fibronectin and vitronectin to mixed self-assembled monolayers SIBB BioBCN2008, 3rd Iberian Biomaterials Congress
(Barcelona, Spain)
2008 Surface Characterization of Nanostructured Surfaces to Induce Selective Apoptosis of Leukemic Cells SIBB BioBCN2008, 3rd Iberian Biomaterials Congress
(Barcelona, Spain)
2008 Molecularly Designed Surfaces for Blood Deheparinization SIBB BioBCN2008, 3rd Iberian Biomaterials Congress
(Barcelona, Spain)
2007 Cell-biomaterial interactions at the nanoscale: how does the cell see the surface? “Nanotechnology in Medicine: Diagnosis and Therapy”
(Vigo, Spain)
2007 NanoEngineered Surfaces for Biomedical Applications Seminários de Nanobiotecnologia (MIT-Portugal)
(Lisboa, Portugal)
2007 NanoEngineering that lives Seminários - Curso de Bioengenharia @ Escola Superior de Biotecnologia (UCP)
(Porto, Portugal)
2006 Selective protein adsorption and platelet adhesion – A molecularly designed surface with C18 ligands 20th European Conference on Biomaterials
(Nantes, France)
2006 Molecularly designed surfaces for selective heparin adsorption 20th European Conference on Biomaterials
(Nantes, France)
2006 Nanoengineered surfaces for blood contact 1st Sino-Portugal Workshop on Health Sciences and Biotechnology
(Hangzhou, China)
2006 Engineered surfaces for selective albumin adsorption 1st Chinese-European Symposium Biomaterials in Regenerative Medicine
(Suzhou, China)
2005 Calcium phosphate microspheres for localised delivery of a therapeutic enzyme 18th Annual Meeting of the International Society for Ceramics in Medicine
(Kyoto, Japan)
2005 The use of model self-assembled monolayers in the elucidation of the role of proteins and white blood cells in blood-material interactions Micro’05Biotec’05
(Povoa do Varzim, Portugal)
2005 Molecularly designed surfaces for albumin selective adsorption European Society for Biomaterials Conference
(Sorrento, Italy)
2005 Adsorption of a therapeutic enzyme to self-assembled monolayers European Society for Biomaterials Conference
(Sorrento, Italy)
2004 Strategies to increase the haemocompatibility of biomaterials 5th Advanced Course in Cell-Material Interactions
(Portugal)
2004 "Interacções entre proteínas do sangue e superfícies modelo" (Interactions between blood proteins and model surfaces) Jornadas ICEMS 2004 – Materiais e Tecnologias para Aplicações Biomédicas
(Lisboa, Portugal)
2004 Protein Adsorption and Leukocyte Adhesion on Self-Assembled Monolayers of Alkanethiols- The Role of the Functional Group and Electrical Charge 9th Seminar and Meeting on Ceramics, Cells and Tissues
(Faenza, Italy)
2004 Protein Adsorption and Leukocyte Adhesion on Molecularly Designed Surfaces III Congresso Latino Americano de Órgãos Artificiais e Biomateriais
(S. Paulo, Brazil)
2004 Protein adsorption on 18-alkyl chains immobilized on self-assembled monolayers II Iberian Congress on Biomaterials and Biosensors – BioÉvora2004
(Évora, Portugal)
2004 Selective albumin adsorption on molecularly design surfaces II Iberian Congress on Biomaterials and Biosensors – BioÉvora2004
(Évora, Portugal)
2004 Interactions of cells and proteins with molecularly designed surfaces European Cells and Materials V - The cell biomaterial reaction
(Davos, Switzerland)
2001 Haemocompatibility of the plasticized PVC used for blood bags 1st International Materials Symposium (Materials’2001)
(Coimbra, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2024/09/01 - Atual Wound-responsive dressing for delivery of bioactive molecules
Orientador
 Mestrado em Aplicações em Biotecnologia e Biologia Sintética- FCUP Universidade do Porto (Mestrado)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/01 - Atual Hybrid hydrogel based on antimicrobial peptide-grafted nanoparticles to treat infected diabetic foot ulcer
Coorientador
 Doctoral Programme in Biomedical Sciences, ICBAS, Portugal. (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/01 - Atual Bactericidal nano-decoys: an attractive approach to fight Helicobacter pylori.
Coorientador
 Doctoral Programme in Biomedical Sciences, ICBAS, Portugal. (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/03 - Atual Covalent immobilization of antimicrobial peptides (AMPs) onto porous titanium oxide surfaces: a new strategy to fight infections and its impact on osteogenic and degradation properties of dental implants.
Orientador
 Doctoral program under regime of cotutelle between Universidade do Porto (PhD in Biomedical Engineering – PRODEB) and Universidade Estadual Paulista “Júlio de Mesquita Filho” (PhD in Materials Science and Technology). (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal

Universidade Estadual Paulista Júlio de Mesquita Filho, Brasil
2019/01 - 2024/10 On the trail of drug free nanostructured lipid carriers selective interaction with Helicobacter pylori
Orientador
 Biotecnologia Molecular e Celular Aplicada às Ciências da Saúde (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/12 - 2024/05 Bioengineered Strategies to Prevent Orthopedic Implant Infections using Antimicrobial Peptides
Coorientador
 Engenharia Biomédica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2019/12/01 - 2024/01 Breaking the classic antibiotic barrier: Micro and nanoparticles for Helicobacter pylori management
Orientador
 Engenharia Biomédica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2019/12/01 - 2024 BioHeal - Bioactivatable modular dressing for chronic infected wounds
Orientador
 Engenharia Biomédica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2022/07 - 2023/12 Developing of an antimicrobial coating to prevent vascular graft infections.
Coorientador
 Mestrado em engenharia biomedica (Mestrado)
Universidade do Minho, Portugal
2023/02 - 2023/09/15 Temperature Sensitive Nanoparticles for Antimicrobial Peptide Controlled Release
Orientador
 Mestrado em Bioengenharia - Ramo Bioengenharia Molecular (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/02 - 2022/11 Development of innovative systems for the treatment of infected wounds
Coorientador
 Mestrado em Engenharia Biomédica (MEB) (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2018/01 - 2022/02 Staphylococcus aureus implant ­associated biofilms: Development of a novel nanoparticle­ based drug delivery system
Coorientador
 Biotecnologia Molecular e Celular Aplicada às Ciências da Saúde (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/02 - 2021/10 Developing an antimicrobial coating to prevent abdominal aortic graft infections (AGIs)
Orientador de Ana Manuela Sá Guimarães
 Mestrado em Bioengenharia - Ramo Bioengenharia Molecular (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2020/02 - 2021/10 Improving Nanostructured Lipid Carriers activity: development of pH-responsive systems for gastric settings
Coorientador de Sandra Gomes
 Bioengenharia (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2020/02 - 2021/10 Antimicrobial nanoparticles to fight bacterial wound infection
Coorientador de Antonio Ramoa
 Bioengenharia (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2019/10 - 2020/10 After the antibiotic era: effect of Nanostructured Lipid Carriers against Helicobacter pylori biofilms
Coorientador
 Bioengenharia (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2019/02 - 2020/10 Bioengineered decoys for Helicobacter pylori
Coorientador
 Engenharia Biomédica (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2016/10 - 2020/04 Graphene based materials for blood contacting devices
Coorientador
 Biologia Básica e Aplicada (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/02 - 2020/02 SAAP 148 antimicrobial and osteoimmunomodulatory activity in solution and in PLGA coatings
Coorientador
 Bioengenharia (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2013/09 - 2018/04 CLAMP – CLick chemistry as a tool to create AntiMicrobial Peptide based material
Coorientador
 Engenharia Biomédica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2017 - 2018 Antibiotic free nano/microparticles to fight Helicobacter pylori
Orientador
 Engenharia Biomédica (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2017 - 2018 Interaction of chitosan microspheres with human gastrointestinal microbiota
Coorientador
 Engenharia Biomédica (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2016 - 2017 Development of antimicrobial coatings based on antimicrobial peptides
Coorientador
 Bioengenharia (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2013 - 2017 Lipid-based Nanostrategies to fight Helicobacter pylori gastric infection
Orientador
 Ciências Biomédicas (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 - 2017 Effect of industrial GMP human plasma derived supplement on hMSC behaviour
Orientador
 Engenharia Biomédica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2015/02 - 2016/10 Coatings based on antimicrobial peptides for prevention of bone implant associated infections
Coorientador
 Engenharia Biomédica (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2015/02 - 2016/07 Prevention of intravascular catheter-related infections
Orientador
 Engenharia Biomédica (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2010 - 2015 Surface-immobilized Antimicrobial Peptides (AMPs) for prevention of implant-related osteomyelitis
Orientador
 Engenharia Biomédica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2011/02 - 2013/10 Antimicrobial Peptides against Helicobacter pylori
Orientador
 Engenharia Biomédica (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2007 - 2013 Engineering surfaces to enhance Helicobacter pylori specific binding
Orientador
 Engenharia Biomédica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2006 - 2012 Molecular design of surfaces towards more effective anticoagulation strategies for blood-contacting medical devices
Orientador
 Engenharia Biomédica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2009 - 2011 Blood compatibility of albumin-binding poly(2-hydroxyethyl methacrylate)
Orientador
 Engenharia Biomédica (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2009 - 2011 Ultrathin films as a plateform to study Helicobacter pylori adhesion to chitosan
Orientador
 Engenharia Biomédica (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2010/03 - 2010/11 Development of Notch Signaling Biomaterials as a tool to control stem cell behavior
Coorientador
 Engenharia Biomédica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2003 - 2009 Molecularly engineered materials for selective albumin binding to reduce the risk of thrombus formation
Coorientador
 Engenharia Biomédica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2005 - 2008 Application of ellipsometry to study the interactions between proteins and surface thin films
Coorientador
 Engenharia Biomédica (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2003 - 2005 Effect of surface chemical modification on hydrophilicity, protein adsorption and platelet adhesion
Coorientador
 Engenharia Biomédica (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2024/12/02 - 2024/12/06 Advanced Training Course in Molecular Bioengineering - Molecularly engineered interfaces: from biosensing to emergent biomedical applications (Co-Chair) (2024)
Oficina (workshop) (Coorganizador)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/10/25 - 2023/10/27 Atomic Force Microscopy applied to Life Sciences | 3rd Ed. (Co-Chair) (2023)
Oficina (workshop)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/06/25 - 2023/06/25 Bio2SkinAdvanced webinar: Benefits of the new generation of adhesives on the treatment of wounds (Co-Chair) (2023)
Conferência (Coorganizador)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/01/27 - 2023/01/27 MOBILIsE Launch event: Molecular Bioengineering: Challenges in Industrial and Clinical Translation (Chair) (2023)
Outro (Presidente da Comissão Organizadora)
 Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/09/05 - 2021/09/09 31st Conference of the European Society for Biomaterials that will be held in Porto, Portugal, from September 5-9, 2021 (Co-Chair) (2021/09/05)
2019/11/06 - 2019/11/08 Course Atomic Force Microscopy applied to Life Sciences | 2nd Ed - Porto, Portugal - Co-chair (2019/11/06 - 2019/11/08)
Oficina (workshop)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/05/21 - 2017/05/24 6th China-Europe Symposium on Biomaterials in Regenerative Medicine – CESB2017, Porto, Portugal - Symposium Co-Chair (2017/05/21 - 2017/05/24)
Simpósio
2013 - 2013 Engineered Surfaces for Protein-Biomaterial Interactions – Module on the Marie Curie project IB2; 7-18 2013; Porto, Portugal - Coordinator of the Training Program (2013 - 2013) Instituto Nacional de Engenharia Biomédica, Portugal
2009/06/22 - 2009/06/26 10th Advanced Course on Cell-Materials Interactions. Self-Assembly: from Nature to Clinics, Porto, Portugal - Organizing Committee (2009/06/22 - 2009/06/26)
2008/06/16 - 2008/06/20 9th Advanced Course on Cell-Materials Interactions. Bioinspired Matrices for Tissue Regeneration, Porto, Portugal - Organizing Committee (2008/06/16 - 2008/06/20)
2007/06/18 - 2007/06/22 8th Advanced Course on Cell-Materials Interactions. Inflammation in Tissue Repair and regeneration, Porto, Portugal - Organizing Committee & Coordinator of the Topic B of Lab Session (Effect of Surface Chemistry on Human Leukocyte Adhesion); (2007/06/18 - 2007/06/22)
2006/06/19 - 2006/06/23 7th Advanced Course on Cell-Materials Interactions. Regenerative Medicine; Porto, Portugal – Organizing Committee (2006/06/19 - 2006/06/23)
2005/06/20 - 2005/06/24 6th Advanced Course on Cell-Materials Interactions at Molecular Level; Porto, Portugal – Scientist in Charge (2005/06/20 - 2005/06/24)
2004/07/05 - 2004/07/09 5th Advanced Course on Cell-Materials Interactions; Porto, Portugal – Organizing Committee; (2004/07/05 - 2004/07/09)

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2024/12 New insights into Helicobacter Pylori bacteriophages´ role and applications.
Arguente
 Rute Vanessa Novais Ferreira (Doutoramento)
Universidade do Minho Departamento de Engenharia Biológica, Portugal
2024/06 Combinatory effect of antimicrobial and immunomodulatory peptides functionalized onto poly(vinyl alcohol)-cellulosic compounds electrospun mats for the treatment of chronic wounds
Arguente principal
 Marta Albertina Fernandes Teixeira (Doutoramento)
Universidade do Minho Departamento de Engenharia Têxtil, Portugal
2023/10/30 Antimicrobial flexible coating material for the car sharing segment of the automotive industry
Arguente principal
 Tiago Miguel Castro Costa (Doutoramento)
Universidade do Minho Escola de Ciências da Saúde, Portugal
2023/05 Innovative Nanoparticles for Targeted Therapy Delivery in Gastrointestinal Cancer
Arguente
 Francisca Oliveira Mesquita Diniz (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/04 Electrochemical immunosensors for detection of neurodegenerative diseases biomarkers
Arguente principal
 Pedro Jorge da Silva Carneiro (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2020/02 Surface biofunctionalization of polycaprolactone fibrous meshes for skeletal and neural tissue advanced therapies Marta Alexandra Rodrigues Casanova (Doutoramento)
Universidade do Minho, Portugal
2017/12 Delivery of siRNAs directed to CDX2: a strategy to revert gastric intestinal metaplasia Ana Adelaide Direito Sadio (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
2017/10 Functionalized nanoparticles for targeted gene delivery to the nervous system Carla Marina Pereira Gomes (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2017/10 Studies of interphase formation between biomolecules and metal and oxide surfaces in aqueous environment Marta Pereira Pinheiro (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2015/07 Poly(¿-glutamic acid) (¿-PGA) and ¿-PGA/chitosan polyelectrolyte complexes for cartilage regeneration Joana Isabel da Costa Antunes (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2015/02 Molecularly designed self-assembling matrices for applications in regenerative medicine Daniela Sofia Dias Ferreira (Doutoramento)
Universidade do Minho, Portugal
2014/12 Development of vascular grafts of bacterial cellulose Alexandre Filipe Leitão (Doutoramento)
Universidade do Minho, Portugal
2013/12 Immobilization of biomolecules into biodegradable polymeric based substrates for selective recruitment and adhesion of cells for tissue engineering applications Catarina de Almeida Custódio (Doutoramento)
Universidade do Minho, Portugal
2013/01 Controlled release of tethered peptides from alginate hydrogels via enzymatic linker degradation Mariana Moreira Barbosa (Mestrado)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2012/04 Design of novel bone regenerative therapeutic strategies based on macrophage released factores: from model surfaces to an in vivo delivery system Joana Maciel Soares (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2008/12 Development of quantitative microparticle-based assays for DNA hybridization Sofia de Medina Aires Martins (Doutoramento)
2007/05 Albumin and fibronectin adsorption and osteoblast adhesion on titanium oxides Susana Sousa Mendes de Freitas (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2024 - Atual Biomaterials Advances (JOURNAL EDITORIAL BOARD )

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2013 - Atual Molecular Biointerfaces Bioengenharia (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2013 - Atual Advanced Experimental Techniques Course Biotecnologia Molecular e Celular Aplicada às Ciências da Saúde (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013 - 2018 Tissue Engineering module GABBA Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2013 - 2015 Nanotechnology in Health Bioengenharia (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2010 - 2013 Nanomedicine (restructuring of the course) Bioengenharia (Mestrado integrado) Universidade do Porto Faculdade de Engenharia, Portugal
2009 - 2013 Nanostructured Materials (restructuring of the course) Bioengenharia (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2021 - Atual French Foundation for Medical Research (FRM - Fondation pour la Recherche Médicale) for Projects in Regenerative Medicine
2017 - Atual Portuguese Foundation for Science and Technology (FCT) for projects in the scope of transnational researcher mobility
2006 - Atual Referee of several journals in biomedical engineering area: Acta Biomaterialia/Biomaterials; Journal of Biomedical Materials Research A; Journal of Materials Science: Materials in Medicine; Journal of the Royal Society Interface; Langmuir; Biomatter; Colloids and Surfaces B: Biointerfaces; Drug Delivery
2014 - 2014 Portuguese Foundation for Science and Technology (FCT) for PhD and Post-Doc scholarship attribution in the area of Nanotecnologia Fundação para a Ciência e a Tecnologia, Portugal
2013 - 2013 Portuguese Foundation for Science and Technology (FCT) for PhD and Post-Doc scholarship attribution in the area of Bioengenharia e Biotecnologia
2011 - 2012 Portuguese Foundation for Science and Technology (FCT) for PhD and Post-Doc scholarship attribution in the area of Ciências da Saúde

Tutoria

Tópico Nome do aluno
2025/02/01 - Atual BiDress- Bioactive and Biodegradable wound Dressing for infected chronic wounds (2023.08230.CEECIND) Luisa Fialho
2011/10 - 2024/12 Antimicrobial coatings based on chitosan-antimicrobial peptides for the prevention of bone implant-associated infection. FCT: SFRH/BPD/79439/2011 Cláudia Monteiro, Post-Doctoral Researcher
2021/01 - 2024/10 Outsmarting bacterial infections: targeted nano/micro biomaterials to eradicate Helicobacter pylori infection. CEECIND/01210/2018 Paula Parreira (Junior Researcher)
2021/02 - 2022/06 Bioengineered Advanced Therapies for Problematic Infected Wounds João Albuquerque Costa (Junior Researcher)
2019/03 - 2022/03 In situ resorbable Antimicrobial Peptides (AMP)-gel coating for orthopaedic infection prevention. CEECIND/01921/2017 Fabíola Moutinho (Junior Researcher)
2021/07 - 2021/11 Bio2Skin Advanced Ana Margarida Pereira (Junior Researcher)
2017/09 - 2020/01 Development of antibiotic-free biomateriais for the erradication of Helicobacter pylori infection: NORTE-01-0145-FEDER-000012 Paula Parreira, Post-Doctoral Researcher
2019/02 - 2019/11 Antibiotic Free Nano/Microparticles to Fight Helicobacter pylori. INEB Project: PYLORIBINDERS PTDC/CTM-BIO/4043/2014 Diana Patricia Ribeiro Fonseca, Research assistant
2018/11 - 2019/11 Bioengineered Advanced Therapies for Problematic Infected Wounds. INEB Project: AntINFECT POCI-01-0145-FEDER-031781 Pedro Miguel Pinto Basto Alves, Research assistant
2016/05 - 2019/02 Development of antimicrobial coatings. Project: NORTE-01-0145-FEDER-000012 Fabíola Costa Moutinho, Post-Doctoral Researcher
2017/07 - 2018/11 Helicobacter pylori specific biomaterials for antibiotic-free treatment of gastric infection: Nanofitins® (NF) immobilization onto gold nanoparticles (AuNP). Project: PYLORIBINDERS PTDC/CTM-BIO/4043/2014 Catarina Seabra, Post-Doctoral Researcher
2014/10 - 2016/03 Biofunctional Coatings for Cardiovascular Interventional Devices. Project JICAM2013 Helena Felgueiras, Post-Doctoral Researcher
2016/02/01 - 2016/02/29 Antimicrobial activity of an AMP immobilized on EG4 self-assembled monolayers (SAMs) Tejesvi Mysore Vishakante Gowda, PhD, Senior Research Fellow
2014/06 - 2015/11 Engineered biomaterials with Helicobacter pylori bactericidal effect: Antimicrobial peptides immobilized on Chitosan Micro/Nanoparticles. INEB Project: PTDC/CTM-BPC/121149/2010 Ricardo Emanuel Silva Carvalho, Research assistant
2014/02 - 2014/08 Engineered biomaterials with Helicobacter pylori bactericidal effect: Antimicrobial peptides immobilized on self assembled monolayers (AMPs-SAMs). INEB Project: PTDC/CTM-BPC/121149/2010 Vanessa Graça, Research assistant
2013/02 - 2013/12 Engineered biomaterials with Helicobacter PYLORI bacteriCIDAL effect: Antimicrobial peptides chitosan microspheres (AMPs-ChMic). Project: PTDC/CTM-BPC/121149/2010 Joana Gomes, Post-Doctoral Researcher
2010/01 - 2013/05 Glycosylation of mucoadhesive microspheres to eliminate Helicobacter pylori gastric colonization. FCT Fellow Inês Gonçalves, Post-Doctoral Researcher
2011 - 2012 Helicobacter pylori adhesion to chitosan microspheres in the presence and absence of gastric mucins & The effect of small antimicrobial peptides (AMP) before and after chitosan immobilization onto Staphylococcus aureus Mariana Fernandes, Research assistant
2009 - 2010 Immobilization of glycosylated compounds on chitosan. INEB Project: PTDC/CTM/65330/2006 José Ricardo Oliveira, Research assistant
2008/03 - 2008/07 Adhesion studies of Helicobacter pylori to nanostructured surfaces. INEB Gisela Ferreira, Research assistant
2008/03 - 2008/07 Leukocyte and platelet adhesion o heparin-binding nanostructured surfaces. INEB Vanessa Ochoa-Mendes, Research assistant
2007/11 - 2008/06 Development of crosslinked chitosan microspheres with capacity to resist to the stomach acidic conditions and release antibodies for Helicobacter pylori. INEB Stefania Nardecchia, Research assistant
2006 - 2007 Heparin binding surfaces. INEB Pedro Salgueiro, Research assistant
Distinções

Prémio

2023 Best oral communication ( Pedro Alves) at the 33rd Conference of the European Society for Biomaterials (ESB 2023), September 2023, Davos, Switzerland
2021 1st prize on the "Business Ignition Programme 2020"
Banco Santander Portugal, Portugal

Universidade do Porto, Portugal
2020 Best Poster Award (Diana Fonseca). A deadly hug: chitosan microspheres functionalized with MSI-78A antimicrobial peptide kill Helicobacter pylori. 33rd Workshop of the European Helicobacter and Microbiota Study Group (online), September 2020
2020 Best oral presentation (Pedro Alves). Reduction in viable surface-adhered bacteria promoted by efficient conjugation of antimicrobial peptide (Dhvvar5) onto chitosan. 1st edition of EUGLOH Annual Student Research Conference, September 2020
2018 ANTIBIOCOAT project - Best innovation Project Award in the scope of the RESOLVE-Health Awards 2018 (Team: Fabiola Costa/ Martins MCL / Rita Mota/ Paula Tamagnini)
2017 ANTIBIOCOAT project - SRS Advogados AWARD in the scope of the I3S-Hovione Capital Health Innovation Prize (Team: Rita Matos, Fabiola Costa, Paula Tamagnini and Martins MCL (September 2017)
2017 Best Poster Award (Fabíola Costa). Effect of surface immobilized N-acetylcysteine on bacteria and cell adhesion. 6th China-Europe Symposium on Biomaterials in Regenerative Medicine-CESB20. Costa F, Sousa DM, Lamghari M, Gomes P, Martins MCL
2013 Best Poster Award (Fabíola Costa). Enhancement of chitosan antibacterial properties by antimicrobial peptide grafting. EUCHIS 2013 - International Conference of the European Chitin Society, Porto, Portugal. Costa F, Maia S, Gomes P, Martins MCL
2011 Costa F, Carvalho IF, Montelaro RC, Gomes P, Martins MCL.Covalent immobilization of antimicrobial peptides (AMPs) onto biomaterial surfaces. Acta Bioamaterialia. 2011; 7 (4): 1431-1440: One of the 6 high quality articles selected by the Acta Biomaterilia
2011 Best Paper published in Journal of Materials Science-Materials in Medicine. "Gonçalves IC, Martins MCL, Barbosa JN, Oliveira P, Barbosa MA, Ratner BD. Platelet and Leukocyte Adhesion to Albumin Binding Self-Assembled Monolayers.
2009 Best Poster Award (Sidónio Freitas). Immobilization of thrombin inhibitors on self-assembled monolayers (SAMs): Effect on the adsorption and activity of thrombin. 22nd European Conference on Biomaterials, Lausane, CH. Freitas SC, Barbosa MA, Martins MCL
2008 Best Poster Award (Raquel Gonçalves). Development of Nanostructured Surfaces to Induce Apoptosis of Leukemic Cells, 9th Advanced Summer Course in Cell-Material Interactions, Porto, Portugal. Goncalves R, Martins MCL, Almeida-Porada G, Barbosa MA
2006 “Pulido Valente Ciência 2006” (Inês Gonçalves) – best research work published in the area “Physics and Engineering – Applications to the study of disease and medical practice”, whose first author is under 35 years old
2005 Best Oral presentation (Inês Gonçalves). Molecularly designed surfaces for albumin selective adsorption. European Society for Biomaterials Conference,11-15 September 2005, Sorrento, Italy. Gonçalves IC, Martins MCL, Barbosa MA, Naeemi E, Ratner BD

Título

2020 Fellow Biomaterials Science and Engineering (FBSE): nomination by the International Union of Societies for Biomaterials Science and Engineering (IUSBSE)