Artigo em revista |
- Sergio Rutella; Jayakumar Vadakekolathu; Francesco Mazziotta; Stephen Reeder; Tung-On Yau; Rupkatha Mukhopadhyay; Benjamin
Dickins; et al. "Signatures of immune dysfunction predict outcomes and define checkpoint blockade-unresponsive microenvironments
in acute myeloid leukemia". Journal of Clinical Investigation (2022): https://doi.org/10.1172/JCI159579.
10.1172/JCI159579
- Tung On Yau; Jayakumar Vadakekolathu; Gemma Ann Foulds; Guodong Du; Benjamin Dickins; Christos Polytarchou; Sergio Rutella.
"Hyperactive neutrophil chemotaxis contributes to anti-tumor necrosis factor-a treatment resistance in inflammatory bowel
disease". Journal of Gastroenterology and Hepatology 37 3 (2022): 531-541. https://doi.org/10.1111/jgh.15764.
10.1111/jgh.15764
- Raquel Alves; Ana Cristina Gonçalves; Sergio Rutella; António M. Almeida; Javier De Las Rivas; Ioannis P. Trougakos; Ana Bela
Sarmento Ribeiro. "Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia—From Molecular Mechanisms to Clinical
Relevance". Cancers 13 19 (2021): 4820-4820. https://doi.org/10.3390/cancers13194820.
10.3390/cancers13194820
- Laura Lestón Pinilla; Aslihan Ugun-Klusek; Sergio Rutella; Luigi A. De Girolamo. "Hypoxia Signaling in Parkinson’s Disease:
There Is Use in Asking “What HIF?”". Biology 10 8 (2021): 723-723. https://doi.org/10.3390/biology10080723.
10.3390/biology10080723
- Uy, Geoffrey L.; Aldoss, Ibrahim; Foster, Matthew C.; Sayre, Peter H.; Wieduwilt, Matthew J.; Advani, Anjali S.; Godwin, John
E.; et al. "Flotetuzumab as salvage immunotherapy for refractory acute myeloid leukemia". Blood 137 6 (2021): 751-762.
http://dx.doi.org/10.1182/blood.2020007732.
10.1182/blood.2020007732
- Raquel Alves; Stephanie E. B. McArdle; Jayakumar Vadakekolathu; Ana Cristina Gonçalves; Paulo Freitas-Tavares; Amélia Pereira;
Antonio M. Almeida; Ana Bela Sarmento-Ribeiro; Sergio Rutella. "Flow cytometry and targeted immune transcriptomics identify
distinct profiles in patients with chronic myeloid leukemia receiving tyrosine kinase inhibitors with or without interferon-a".
Journal of Translational Medicine (2020): https://doi.org/10.1186/s12967-019-02194-x.
10.1186/s12967-019-02194-x
- Cesano, Alessandra; Cannarile, Michael A; Gnjatic, Sacha; Gomes, Bruno; Guinney, Justin; Karanikas, Vaios; Karkada, Mohan;
et al. "Society for Immunotherapy of Cancer clinical and biomarkers data sharing resource document: Volume II—practical challenges".
Journal for ImmunoTherapy of Cancer 8 2 (2020): e001472. http://dx.doi.org/10.1136/jitc-2020-001472.
10.1136/jitc-2020-001472
- Rutella, Sergio; Cannarile, Michael A; Gnjatic, Sacha; Gomes, Bruno; Guinney, Justin; Karanikas, Vaios; Karkada, Mohan; et
al. "Society for Immunotherapy of Cancer clinical and biomarkers data sharing resource document: Volume I—conceptual challenges".
Journal for ImmunoTherapy of Cancer 8 2 (2020): e001389. http://dx.doi.org/10.1136/jitc-2020-001389.
10.1136/jitc-2020-001389
- Rutella, Sergio. "Characteristics of Tumor-Infiltrating Lymphocytes Prior to and During Immune Checkpoint Inhibitor Therapy.".
Frontiers in Immunology (2020): https://europepmc.org/articles/PMC7064638.
10.3389/fimmu.2020.00364
- Rutella, Sergio. "TP53 abnormalities correlate with immune infiltration and are associated with response to flotetuzumab,
an investigational immunotherapy, in acute myeloid leukemia". [] (2020): http://dx.doi.org/10.1101/2020.02.28.961391.
10.1101/2020.02.28.961391
- Rutella, Sergio. "Immune landscapes predict chemotherapy resistance and immunotherapy response in acute myeloid leukemia".
[] (2019): http://dx.doi.org/10.1101/702001.
10.1101/702001
- Sarah Wagner; Jayakumar Vadakekolathu; Sarah K. Tasian; Heidi Altmann; Martin Bornhäuser; A. Graham Pockley; Graham R. Ball;
Sergio Rutella. "A parsimonious 3-gene signature predicts clinical outcomes in an acute myeloid leukemia multicohort study".
Blood Advances 3 8 (2019): 1330-1346. https://doi.org/10.1182/bloodadvances.2018030726.
10.1182/bloodadvances.2018030726
- Rutella, Sergio. "Reverting Immune Suppression to Enhance Cancer Immunotherapy.". Frontiers in Oncology (2019): https://europepmc.org/articles/PMC6985581.
10.3389/fonc.2019.01554
- Jan Davidson-Moncada; Elena Viboch; Sarah Church; Sarah Warren; Sergio Rutella. "Dissecting the Immune Landscape of Acute
Myeloid Leukemia". Biomedicines 6 4 (2018): 110-110. https://doi.org/10.3390/biomedicines6040110.
10.3390/biomedicines6040110
- Sarah Tasian; Martin Bornhäuser; Sergio Rutella. "Targeting Leukemia Stem Cells in the Bone Marrow Niche". Biomedicines
6 1 (2018): 22-22. https://doi.org/10.3390/biomedicines6010022.
10.3390/biomedicines6010022
- Rutella, Sergio. "Capturing the complexity of the immune microenvironment of acute myeloid leukemia with 3D biology technology.".
Journal of Clinical Oncology (2018): http://dx.doi.org/10.1200/jco.2018.36.5_suppl.50.
10.1200/jco.2018.36.5_suppl.50
- Dimitrios Zafeiris; Sergio Rutella; Graham Roy Ball. "An Artificial Neural Network Integrated Pipeline for Biomarker Discovery
Using Alzheimer's Disease as a Case Study". Computational and Structural Biotechnology Journal 16 (2018): 77-87. https://doi.org/10.1016/j.csbj.2018.02.001.
10.1016/j.csbj.2018.02.001
- Matlung, H.L.; Babes, L.; Zhao, X.W.; van Houdt, M.; Treffers, L.W.; van Rees, D.J.; Franke, K.; et al. "Neutrophils Kill
Antibody-Opsonized Cancer Cells by Trogoptosis". Cell Reports 23 13 (2018): 3946-3959.e6. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048859204&partnerID=MN8TOARS.
10.1016/j.celrep.2018.05.082
- Pockley, A.G.; Lindsay, J.O.; Foulds, G.A.; Rutella, S.; Gribben, J.G.; Alexander, T.; Snowden, J.A.. "Immune reconstitution
after autologous hematopoietic stem cell transplantation in Crohn's disease: Current status and future directions. A review
on behalf of the EBMT autoimmune diseases working party and the autologous stem cell transplantation in refractory CD-Low
Intensity Therapy Evaluation study investigators". Frontiers in Immunology 9 APR (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85045004182&partnerID=MN8TOARS.
10.3389/fimmu.2018.00646
- Foulds, G.A.; Vadakekolathu, J.; Abdel-Fatah, T.M.A.; Nagarajan, D.; Reeder, S.; Johnson, C.; Hood, S.; et al. "Immune-phenotyping
and transcriptomic profiling of peripheral blood mononuclear cells from patients with breast cancer: Identification of a 3
gene signature which predicts relapse of triple negative breast cancer". Frontiers in Immunology 9 SEP (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85053153382&partnerID=MN8TOARS.
10.3389/fimmu.2018.02028
- Dimitrios Zafeiris; Jayakumar Vadakekolathu; Sarah Wagner; Alan Graham Pockley; Graham Roy Ball; Sergio Rutella. "Discovery
and application of immune biomarkers for hematological malignancies". Expert Review of Molecular Diagnostics (2017):
1-18. https://doi.org/10.1080/14737159.2017.1381560.
10.1080/14737159.2017.1381560
- Rutella, Sergio. "T-Cell Manipulation Strategies to Prevent Graft-Versus-Host Disease in Haploidentical Stem Cell Transplantation".
Biomedicines (2017): http://www.mdpi.com/2227-9059/5/2/33.
10.3390/biomedicines5020033
- Stroncek DF; Butterfield LH; Cannarile MA; Dhodapkar MV; Greten TF; Grivel JC; Kaufman DR; et al. "Systematic evaluation of
immune regulation and modulation.". (2017): http://europepmc.org/abstract/med/28331613.
10.1186/s40425-017-0223-8
- Ženka J; Caisová V; Uher O; Nedbalová P; Kvardová K; Masáková K; Krejcová G; et al. "Abstracts from the 4th ImmunoTherapy
of Cancer Conference: Prague, Czech Republic. 20–22 March 2017.". (2017): http://europepmc.org/abstract/PMC/PMC5374589.
- Raffaele Frazzi; Charles Auffray; Angela Ferrari; Perla Filippini; Sergio Rutella; Alfredo Cesario. "Integrative systems medicine
approaches to identify molecular targets in lymphoid malignancies". Journal of Translational Medicine 14 1 (2016):
http://dx.doi.org/10.1186/s12967-016-1018-2.
10.1186/s12967-016-1018-2
- Deola, S.; Cugno, C.; Comoli, P.; Guido, I.; Rubert, L.; Zecca, M.; Zanolini, D.; et al. "Evidence for CD19B–CD8T cell interactions
in blood and tissues from patients with GvHD". Bone Marrow Transplantation (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84994673834&partnerID=MN8TOARS.
10.1038/bmt.2016.294
- Sala E; Genua M; Petti L; Anselmo A; Arena V; Cibella J; Zanotti L; et al. "Mesenchymal Stem Cells Reduce Colitis in Mice
via Release of TSG6, Independently of Their Localization to the Intestine.". (2015): http://europepmc.org/abstract/med/25790743.
10.1053/j.gastro.2015.03.013
- Genua M; D'Alessio S; Cibella J; Gandelli A; Sala E; Correale C; Spinelli A; et al. "The urokinase plasminogen activator receptor
(uPAR) controls macrophage phagocytosis in intestinal inflammation.". (2015): http://europepmc.org/abstract/med/24848264.
10.1136/gutjnl-2013-305933
- Locatelli F; Masetti R; Rondelli R; Zecca M; Fagioli F; Rovelli A; Messina C; et al. "Outcome of children with high-risk acute
myeloid leukemia given autologous or allogeneic hematopoietic cell transplantation in the aieop AML-2002/01 study.". (2015):
http://europepmc.org/abstract/med/25387094.
10.1038/bmt.2014.246
- Piscaglia AC; Rutella S; Laterza L; Cesario V; Campanale M; Cazzato IA; Ianiro G; et al. "Circulating hematopoietic stem cells
and putative intestinal stem cells in coeliac disease.". (2015): http://europepmc.org/abstract/med/26160352.
10.1186/s12967-015-0591-0
- Pittari G; Filippini P; Gentilcore G; Grivel JC; Rutella S. "Revving up Natural Killer Cells and Cytokine-Induced Killer Cells
Against Hematological Malignancies.". (2015): http://europepmc.org/abstract/med/26029215.
10.3389/fimmu.2015.00230
- Yadav SK; Gupta RK; Saraswat VA; Rangan M; Thomas MA; Rutella S; Danese S; et al. "Reduced cortical thickness in patients
with acute-on-chronic liver failure due to non-alcoholic etiology.". (2015): http://europepmc.org/abstract/med/26444271.
10.1186/s12967-015-0679-6
- Locatelli, F.; Masetti, R.; Rondelli, R.; Zecca, M.; Fagioli, F.; Rovelli, A.; Messina, C.; et al. "Erratum: Outcome of children
with high-risk acute myeloid leukemia given autologous or allogeneic hematopoietic cell transplantation in the AIEOP AML-2002/01
study (Bone Marrow Transplantation (2015) 15 (320))". Bone Marrow Transplantation 50 2 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84922322688&partnerID=MN8TOARS.
10.1038/bmt.2014.291
- Cugno, C.; Deola, S.; Filippini, P.; Stroncek, D.F.; Rutella, S.; Cugno C; Deola S; et al. "Granulocyte transfusions in children
and adults with hematological malignancies: Benefits and controversies". Journal of Translational Medicine 13 1 (2015):
http://www.scopus.com/inward/record.url?eid=2-s2.0-84960462980&partnerID=MN8TOARS.
10.1186/s12967-015-0724-5
- Li Pira G; Ivaldi F; Starc N; Landi F; Rutella S; Locatelli F; Sacchi N; Tripodi G; Manca F. "A registry of HLA-typed donors
for production of virus-specific CD4 and CD8 T lymphocytes for adoptive reconstitution of immune-compromised patients.". (2014):
http://europepmc.org/abstract/med/25041366.
10.1111/trf.12754
- Filippini P; Rutella S. "Recent advances on cellular therapies and immune modulators for graft-versus-host disease.". (2014):
http://europepmc.org/abstract/med/25196777.
10.1586/1744666X.2014.955475
- Di Nardo M; Locatelli F; Di Florio F; Cecchetti C; Amodeo A; Rutella S; Bertaina A. "Extracorporeal membrane oxygenation as
a bridge to allogeneic T-cell depleted hematopoietic stem cell transplantation in infants with severe combined immune deficiency:
is it feasible?". (2014): http://europepmc.org/abstract/med/25112503.
10.1007/s00134-014-3432-3
- Bertaina A; Merli P; Rutella S; Pagliara D; Bernardo ME; Masetti R; Pende D; et al. "HLA-haploidentical stem cell transplantation
after removal of aß+ T and B cells in children with nonmalignant disorders.". (2014): http://europepmc.org/abstract/med/24869942.
10.1182/blood-2014-03-563817
- Rutella, Sergio. "TUMOUR BIOLOGY.". (2014): http://europepmc.org/abstract/PMC/PMC4046298.
- Rutella S; Valentini CG; Ceccarelli S; Romano MT; Brescia LP; Milano GM; Locatelli F. "Extracorporeal photopheresis for paediatric
patients experiencing graft-versus-host disease (GVHD).". (2014): http://europepmc.org/abstract/med/24780391.
10.1016/j.transci.2014.04.004
- Li Pira G; Ivaldi F; Starc N; Landi F; Locatelli F; Rutella S; Tripodi G; Manca F. "Miniaturized and high-throughput assays
for analysis of T-cell immunity specific for opportunistic pathogens and HIV.". (2014): http://europepmc.org/abstract/med/24477854.
10.1128/CVI.00660-13
- Genua M; Rutella S; Correale C; Danese S. "The triggering receptor expressed on myeloid cells (TREM) in inflammatory bowel
disease pathogenesis.". (2014): http://europepmc.org/abstract/med/25347935.
10.1186/s12967-014-0293-z
- Rutella S; Filippini P; Bertaina V; Li Pira G; Altomare L; Ceccarelli S; Brescia LP; et al. "Mobilization of healthy donors
with plerixafor affects the cellular composition of T-cell receptor (TCR)-aß/CD19-depleted haploidentical stem cell grafts.".
(2014): http://europepmc.org/abstract/med/25179788.
10.1186/s12967-014-0240-z
- Di Nardo, M.; Li Pira, G.; Amodeo, A.; Cecchetti, C.; Giorda, E.; Ceccarelli, S.; Brescia, L.P.; et al. "Adoptive immunotherapy
with antigen-specific T cells during extracorporeal membrane oxygenation (ECMO) for adenovirus-related respiratory failure
in a child given haploidentical stem cell transplantation". Pediatric Blood and Cancer 61 2 (2014): 376-379. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890863790&partnerID=MN8TOARS.
10.1002/pbc.24753
- Di Nardo, M.; Locatelli, F.; Palmer, K.; Amodeo, A.; Lorusso, R.; Belliato, M.; Cecchetti, C.; et al. "Extracorporeal membrane
oxygenation in pediatric recipients of hematopoietic stem cell transplantation: an updated analysis of the Extracorporeal
Life Support Organization experience". Intensive Care Medicine (2014): 1-3. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893926762&partnerID=MN8TOARS.
10.1007/s00134-014-3240-9
- Van De Vijver, E.; Tool, A.T.J.; Sanal, Ö.; Çetin, M.; Ünal, S.; Aytac, S.; Seeger, K.; et al. "Kindlin-3-independent adhesion
of neutrophils from patients with leukocyte adhesion deficiency type III". Journal of Allergy and Clinical Immunology
133 4 (2014): 1215-1218. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897412977&partnerID=MN8TOARS.
10.1016/j.jaci.2013.10.020
- Masetti, R.; Togni, M.; Astolfi, A.; Pigazzi, M.; Indio, V.; Rivalta, B.; Manara, E.; et al. "Whole transcriptome sequencing
of a paediatric case of de novo acute myeloid leukaemia with del(5q) reveals RUNX1-USP42 and PRDM16-SKI fusion transcripts".
British Journal of Haematology (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84896588798&partnerID=MN8TOARS.
10.1111/bjh.12855
- Folgiero, V.; Goffredo, B.M.; Filippini, P.; Masetti, R.; Bonanno, G.; Caruso, R.; Bertaina, V.; et al. "Indoleamine 2,3-dioxygenase
1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia". Oncotarget
5 8 (2014): 2052-2064. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899544576&partnerID=MN8TOARS.
- Balduzzi A; Basso G; Fagioli F; Favre C; Foà R; Lanino E; Locatelli F; et al. "Hematopoietic stem cell transplantation for
children with high-risk acute lymphoblastic leukemia in first complete remission: a report from the AIEOP registry.". (2013):
http://europepmc.org/abstract/med/23445874.
10.3324/haematol.2012.079707
- Danese S; Rutella S; Vetrano S. "Mesenchymal stromal cells in inflammatory bowel disease: conspirators within the 'colitogenic
niche'?". (2013): http://europepmc.org/abstract/med/23263523.
10.1136/gutjnl-2012-303903
- Basso G; Biondi A; Casale F; Fagioli F; Lo Nigro L; Locatelli F; Luciani M; et al. "Results of the AIEOP AML 2002/01 multicenter
prospective trial for the treatment of children with acute myeloid leukemia.". (2013): http://europepmc.org/abstract/med/23673857.
10.1182/blood-2013-03-491621
- Rutella S; Folgiero V; Filippini P; Bertaina V; Masetti R; Zecca M; Pira GL; et al. "Indoleamine 2,3-dioxygenase-1 (IDO1)
expression by childhood acute myeloid leukemias inhibits T-cell production of IFN-¿ and confers an unfavorable prognosis.".
(2013): http://europepmc.org/abstract/PMC/PMC3990306.
- De Cuyper, I.M.; Meinders, M.; Van De Vijver, E.; De Korte, D.; Porcelijn, L.; De Haas, M.; Eble, J.A.; et al. "A novel flow
cytometry-based platelet aggregation assay". Blood 121 10 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84876459471&partnerID=MN8TOARS.
10.1182/blood-2012-06-437723
- Correale, C.; Genua, M.; Vetrano, S.; Mazzini, E.; Martinoli, C.; Spinelli, A.; Arena, V.; et al. "Bacterial sensor triggering
receptor expressed on myeloid cells-2 regulates the mucosal inflammatory response". Gastroenterology 144 2 (2013):
http://www.scopus.com/inward/record.url?eid=2-s2.0-84881191683&partnerID=MN8TOARS.
10.1053/j.gastro.2012.10.040
- Biscetti, F.; Pecorini, G.; Straface, G.; Arena, V.; Stigliano, E.; Rutella, S.; Locatelli, F.; et al. "Cilostazol promotes
angiogenesis after peripheral ischemia through a VEGF-dependent mechanism". International Journal of Cardiology 167
3 (2013): 910-916. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880923164&partnerID=MN8TOARS.
10.1016/j.ijcard.2012.03.103
- Iachininoto, M.G.; Nuzzolo, E.R.; Bonanno, G.; Mariotti, A.; Procoli, A.; Locatelli, F.; De Cristofaro, R.; Rutella, S.. "Cyclooxygenase-2
(COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells". Molecules
18 9 (2013): 10132-10145. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885090543&partnerID=MN8TOARS.
10.3390/molecules180910132
- Locatelli, F.; Moretta, F.; Rutella, S.. "Management of relapsed acute lymphoblastic leukemia in childhood with conventional
and innovative approaches". Current Opinion in Oncology 25 6 (2013): 707-715. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885429550&partnerID=MN8TOARS.
10.1097/CCO.0000000000000011
- Ciarapica, R.; De Salvo, M.; Carcarino, E.; Bracaglia, G.; Adesso, L.; Leoncini, P.P.; Dall'Agnese, A.; et al. "The Polycomb
group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx)".
Oncogene (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84887102995&partnerID=MN8TOARS.
10.1038/onc.2013.471
- Guidi, L.; Felice, C.; Procoli, A.; Bonanno, G.; Martinelli, E.; Marzo, M.; Mocci, G.; et al. "FOXP3+ T regulatory cell modifications
in inflammatory bowel disease patients treated with anti-TNF a agents". BioMed Research International 2013 (2013):
http://www.scopus.com/inward/record.url?eid=2-s2.0-84884220285&partnerID=MN8TOARS.
10.1155/2013/286368
- Masetti, R.; Togni, M.; Astolfi, A.; Pigazzi, M.; Manara, E.; Indio, V.; Rizzari, C.; et al. "DHH-RHEBL1 fusion transcript:
A novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia". Oncotarget
4 10 (2013): 1712-1720. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886741350&partnerID=MN8TOARS.
- Locatelli, F.; Merli, P.; Rutella, S.. "At the bedside: Innate immunity as an immunotherapy tool for hematological malignancies".
Journal of Leukocyte Biology 94 6 (2013): 1141-1157. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888769265&partnerID=MN8TOARS.
10.1189/jlb.0613343
- Rutella, S.; Iudicone, P.; Bonanno, G.; Fioravanti, D.; Procoli, A.; Lavorino, C.; Foddai, M.L.; et al. "Adoptive immunotherapy
with cytokine-induced killer cells generated with a new good manufacturing practice-grade protocol". Cytotherapy 14
7 (2012): 841-850. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863926513&partnerID=MN8TOARS.
10.3109/14653249.2012.681038
- Rutella, S.; Locatelli, F.. "Is there a role for cytokine-induced killer cells in cancer immunotherapy?". Immunotherapy
4 9 (2012): 867-869. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867341013&partnerID=MN8TOARS.
10.2217/imt.12.89
- Filippini, P.; Cesario, A.; Fini, M.; Locatelli, F.; Rutella, S.. "The yin and yang of non-neuronal a7-nicotinic receptors
in inflammation and autoimmunity". Current Drug Targets 13 5 (2012): 644-655. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860486209&partnerID=MN8TOARS.
- Rutella, S.; Locatelli, F.. "Targeting multiple-myeloma-induced immune dysfunction to improve immunotherapy outcomes". Clinical
and Developmental Immunology 2012 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84861015140&partnerID=MN8TOARS.
10.1155/2012/196063
- Filippini, P.; Del Papa, N.; Sambataro, D.; Del Bufalo, A.; Locatelli, F.; Rutella, S.. "Emerging concepts on inhibitors of
indoleamine 2,3-dioxygenase in rheumatic diseases". Current Medicinal Chemistry 19 31 (2012): 5381-5393. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870449163&partnerID=MN8TOARS.
10.2174/092986712803833353
- Danese, S.; Fiorino, G.; Rutella, S.. "Regulatory T-cell therapy for Crohn's disease: In vivo veritas". Gastroenterology
143 5 (2012): 1135-1138. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868028136&partnerID=MN8TOARS.
10.1053/j.gastro.2012.09.019
- Locatelli, F.; Schrappe, M.; Bernardo, M.E.; Rutella, S.. "How i treat relapsed childhood acute lymphoblastic leukemia". Blood
120 14 (2012): 2807-2816. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867286348&partnerID=MN8TOARS.
10.1182/blood-2012-02-265884
- Li Pira, G.; Starc, N.; Conforti, A.; Bertaina, A.; Rutella, S.; Locatelli, F.; Manca, F.. "Lymphocyte proliferation specific
for recall, CMV and HIV antigens in miniaturized and automated format". Journal of Immunological Methods 384 1-2 (2012):
135-142. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865589579&partnerID=MN8TOARS.
10.1016/j.jim.2012.07.022
- Bonanno, G.; Mariotti, A.; Procoli, A.; Folgiero, V.; Natale, D.; De Rosa, L.; Majolino, I.; et al. "Indoleamine 2,3-dioxygenase
1 (IDO1) activity correlates with immune system abnormalities in multiple myeloma". Journal of Translational Medicine
10 1 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84870660898&partnerID=MN8TOARS.
10.1186/1479-5876-10-247
- Chiò, A.; Mora, G.; La Bella, V.; Caponnetto, C.; Mancardi, G.; Sabatelli, M.; Siciliano, G.; et al. "Repeated courses of
granulocyte colony-stimulating factor in amyotrophic lateral sclerosis: Clinical and biological results from a prospective
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Expert Opinion on Therapeutic Patents 15 11 (2005): 1595-1616. http://www.scopus.com/inward/record.url?eid=2-s2.0-27944507804&partnerID=MN8TOARS.
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lipophilic camptothecin analogue gimatecan is very active in vitro in human neuroblastoma: A comparative study with SN38 and
topotecan (Biochemical Pharmacology (2005) 70:8 (1125-1136) DOI: 10.1016/j.bcp.2005.07.009)". Biochemical Pharmacology
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Panminerva Medica 46 1 (2004): 49-59. http://www.scopus.com/inward/record.url?eid=2-s2.0-4143057012&partnerID=MN8TOARS.
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of Transplantation of Human Cord Blood Stem Cells in Preimmune Fetal Sheep: The Intracelomic Cavity (Stem Cells (2003) 21
(638-646))". Stem Cells 22 1 (2004): http://www.scopus.com/inward/record.url?eid=2-s2.0-0346250858&partnerID=MN8TOARS.
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Immunology Letters 94 1-2 (2004): 11-26. http://www.scopus.com/inward/record.url?eid=2-s2.0-3242677783&partnerID=MN8TOARS.
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- Rutella, S.; Bonanno, G.; Pierelli, L.; Mariotti, A.; Capoluongo, E.; Contemi, A.M.; Ameglio, F.; et al. "Granulocyte colony-stimulating
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- Leone, G.; Rutella, S.; Voso, M.T.; Fianchi, L.; Scardocci, A.; Pagano, L.. "In vivo priming with granulocyte colony-stimulating
factor possibly enhances the effect of gemtuzumab-ozogamicin in acute myeloid leukemia: Results of a pilot study". Haematologica
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- Perillo, A.; Ferrandina, G.; Pierelli, L.; Rutella, S.; Mancuso, S.; Scambia, G.. "Cytokines alone for PBPC collection in
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(2004): 743-744. http://www.scopus.com/inward/record.url?eid=2-s2.0-6444236099&partnerID=MN8TOARS.
10.1038/sj.bmt.1704584
- Morosetti, R.; Servidei, T.; Mirabella, M.; Rutella, S.; Mangiola, A.; Maira, G.; Mastrangelo, R.; Koeffler, H.P.. "The PPARgamma
ligands PGJ2 and rosiglitazone show a differential ability to inhibit proliferation and to induce apoptosis and differentiation
of human glioblastoma cell lines.". International journal of oncology 25 2 (2004): 493-502. http://www.scopus.com/inward/record.url?eid=2-s2.0-11344266106&partnerID=MN8TOARS.
- Savarino, A.; Lucia, M.B.; Rastrelli, E.; Rutella, S.; Golotta, C.; Morra, E.; Tamburrini, E.; et al. "Anti-HIV Effects of
Chloroquine: Inhibition of Viral Particle Glycosylation and Synergism with Protease Inhibitors". Journal of Acquired Immune
Deficiency Syndromes 35 3 (2004): 223-232. http://www.scopus.com/inward/record.url?eid=2-s2.0-10744225033&partnerID=MN8TOARS.
10.1097/00126334-200403010-00002
- Di Campli, C.; Piscaglia, A.C.; Pierelli, L.; Rutella, S.; Bonnano, G.; Alison, M.R.; Mariotti, A.; et al. "A human umbilical
cord stem cell rescue therapy in a murine model of toxic liver injury". Digestive and Liver Disease 36 9 (2004): 603-613.
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10.1016/j.dld.2004.03.017
- Ferrandina, G.; Pierelli, L.; Perillo, A.; Rutella, S.; Ludovisi, M.; Leone, G.; Mancuso, S.; Scambia, G.. "Lymphocyte recovery
in advanced ovarian cancer patients after high-dose chemotherapy and peripheral blood stem cell plus growth factor support:
Clinical implications". Clinical Cancer Research 9 1 I (2003): 195-200. http://www.scopus.com/inward/record.url?eid=2-s2.0-12244313414&partnerID=MN8TOARS.
- Rutella, S.; Bonanno, G.; Marone, M.; De Ritis, D.; Mariotti, A.; Voso, M.T.; Scambia, G.; et al. "Identification of a novel
subpopulation of human cord blood CD34 -CD133-CD7-CD45+lineage- cells capable of lymphoid/NK cell differentiation after in
vitro exposure to IL-15". Journal of Immunology 171 6 (2003): 2977-2988. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042333426&partnerID=MN8TOARS.
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- Noia, G.; Pierelli, L.; Bonanno, G.; Monego, G.; Perillo, A.; Rutella, S.; Cavaliere, A.F.; et al. "A Novel Route of Transplantation
of Human Cord Blood Stem Cells in Preimmune Fetal Sheep: The Intracelomic Cavity". Stem Cells 21 6 (2003): 638-646.
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- Piccirillo, N.; De Matteis, S.; Laurenti, L.; Chiusolo, P.; Sorà, F.; Pittiruti, M.; Rutella, S.; et al. "Glutamine-enriched
parenteral nutrition after autologous peripheral blood stem cell transplantation: Effects on immune reconstitution and mucositis".
Haematologica 88 2 (2003): 192-200. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037946768&partnerID=MN8TOARS.
- Rutella, S.; Pierelli, L.; Piccirillo, N.; Sica, S.; Serafini, R.; Chiusolo, P.; Paladini, U.; et al. "Efficacy of granulocyte
transfusions for neutropenia-related infections: Retrospective analysis of predictive factors". Cytotherapy 5 1 (2003):
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10.1080/14653240310000047
- Marone, M.; Bonanno, G.; Rutella, S.; Leone, G.; Scambia, G.; Pierelli, L.. "Survival and cell cycle control in early hematopoiesis:
Role of Bcl-2, and the cyclin dependent kinase inhibitors P27 and P21". Leukemia and Lymphoma 43 1 (2002): 51-57. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036119661&partnerID=MN8TOARS.
10.1080/10428190210195
- Marone, M.; De Ritis, D.; Bonanno, G.; Mozzetti, S.; Rutella, S.; Scambia, G.; Pierelli, L.. "Cell cycle regulation in human
hematopoietic stem cells: From isolation to activation". Leukemia and Lymphoma 43 3 (2002): 493-501. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036122603&partnerID=MN8TOARS.
10.1080/10428190290011967
- Marone, M.; Scambia, G.; Bonanno, G.; Rutella, S.; de Ritis, D.; Guidi, F.; Leone, G.; Pierelli, L.. "Transforming growth
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therapy and allogeneic CD34+ peripheral blood progenitor cells transplantation in an HIV/HCV coinfected patient with acute
myeloid leukemia". Experimental Hematology 30 3 (2002): 279-284. http://www.scopus.com/inward/record.url?eid=2-s2.0-18344365190&partnerID=MN8TOARS.
10.1016/S0301-472X(01)00793-7
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the number of peripheral blood B-cells in vitro mainly by effector cell-mediated mechanisms". Haematologica 87 9 (2002):
918-925. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036738061&partnerID=MN8TOARS.
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factor-ß1 causes transcriptional activation of CD34 and preserves haematopoietic stem/progenitor cell activity". British
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10.1046/j.1365-2141.2002.03604.x
- Lucia, M.B.; Rutella, S.; Golotta, C.; Leone, G.; Cauda, R.. "Differential induction of P-glycoprotein and MRP by rifamycins
in T lymphocytes from HIV-1/tuberculosis co-infected patients [3]". AIDS 16 11 (2002): 1563-1565. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037178330&partnerID=MN8TOARS.
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in HIV-infected patients administered highly active antiretroviral therapy and liposomal doxorubicin". Journal of Acquired
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of low-dose interleukin-2 plus G-CSF/EPO early after autologous PBSC transplantation: Effects on immune recovery and NK activity
in a prospective study in women with breast and ovarian cancer". Bone Marrow Transplantation 30 9 (2002): 571-578.
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10.1038/sj.bmt.1703687
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of glutathione S-transferase (GSTM1 and GSTT1) deletions in adult acute myeloid leukemia". Blood 100 8 (2002): 2703-2707.
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after autologous selected peripheral blood progenitor cell transplantation: Comparison of two CD34+ cell-selection systems".
Transfusion 41 6 (2001): 783-789. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034975957&partnerID=MN8TOARS.
10.1046/j.1537-2995.2001.41060783.x
- Teofili, L.; Martini, M.; Di Mario, A.; Rutella, S.; Urbano, R.; Luongo, M.; Leone, G.; Larocca, L.M.. "Expression of p15ink4b
gene during megakaryocytic differentiation of normal and myelodysplastic hematopoietic progenitors". Blood 98 2 (2001):
495-497. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035880261&partnerID=MN8TOARS.
10.1182/blood.V98.2.495
- De Candia, E.; Hall, S.W.; Rutella, S.; Landolfi, R.; Andrews, R.K.; De Cristofaro, R.. "Binding of Thrombin to Glycoprotein
Ib Accelerates the Hydrolysis of Par-1 on Intact Platelets". Journal of Biological Chemistry 276 7 (2001): 4692-4698.
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10.1074/jbc.M008160200
- Rutella, S.; Pierelli, L.; Rumi, C.; Bonanno, G.; Marone, M.; Sica, S.; Capoluongo, E.; et al. "T-cell apoptosis induced by
granulocyte colony-stimulating factor is associated with retinoblastoma protein phosphorylation and reduced expression of
cyclin-dependent kinase inhibitors". Experimental Hematology 29 4 (2001): 401-415. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035070370&partnerID=MN8TOARS.
10.1016/S0301-472X(01)00617-8
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domain involved in the binding to the platelet glycoprotein Ib". Biochemistry 40 44 (2001): 13268-13273. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035818425&partnerID=MN8TOARS.
10.1021/bi010491f
- Lucia, M.B.; Rutella, S.; Leone, G.; Cauda, R.. "HIV protease inhibitors reduce IL-2 release from normal human phytohaemagglutinin-activated
T cells [1]". AIDS 15 17 (2001): 2339-2341. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035941388&partnerID=MN8TOARS.
10.1097/00002030-200111230-00023
- Lucia, M.B.; Rutella, S.; Leone, G.; Vella, S.; Cauda, R.. "HIV-protease inhibitors contribute to P-glycoprotein efflux function
defect in peripheral blood lymphocytes from HIV-positive patients receiving HAART". Journal of Acquired Immune Deficiency
Syndromes 27 4 (2001): 321-330. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035424103&partnerID=MN8TOARS.
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of autologous peripheral CD34+ cells". Acta Haematologica 105 3 (2001): 179-187. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034913999&partnerID=MN8TOARS.
10.1159/000046562
- Rutella, S.; Pierelli, L.; Bonanno, G.; Mariotti, A.; Sica, S.; Sorà, F.; Chiusolo, P.; et al. "Immune reconstitution after
autologous peripheral blood progenitor cell transplantationEffect of interleukin-15 on T-cell survival and effector functions".
Experimental Hematology 29 12 (2001): 1503-1516. http://www.scopus.com/inward/record.url?eid=2-s2.0-18244381053&partnerID=MN8TOARS.
10.1016/S0301-472X(01)00747-0
- Pierelli, L.; Bonanno, G.; Rutella, S.; Marone, M.; Scambia, G.; Leone, G.. "CD105 (endoglin) expression on hematopoietic
stem/progenitor cells". Leukemia and Lymphoma 42 6 (2001): 1195-1206. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035694705&partnerID=MN8TOARS.
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factor administration and T-cell recovery after peripheral blood progenitor cell transplantation in the treatment of solid
tumors: Results from a randomized comparison of G-CSF and GM-CSF". Transfusion 41 12 (2001): 1577-1585. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035682928&partnerID=MN8TOARS.
10.1046/j.1537-2995.2001.41121577.x
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Impact of CD34-cell selection on immunological reconstitution". Leukemia and Lymphoma 42 6 (2001): 1207-1220. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035696938&partnerID=MN8TOARS.
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c-met proto-oncogene and its ligand, hepatocyte growth factor, in Hodgkin disease". Blood 97 4 (2001): 1063-1069. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035865510&partnerID=MN8TOARS.
10.1182/blood.V97.4.1063
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cell activation molecule hpH4 in HIV-infected patients: Correlation with disease status". AIDS Research and Human Retroviruses
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are enriched in primitive circulating progenitors residing in the G0 phase of the cell cycle and contain all bone marrow and
cord blood CD34+/CD38(low/-) precursors". British Journal of Haematology 108 3 (2000): 610-620. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034117227&partnerID=MN8TOARS.
10.1046/j.1365-2141.2000.01869.x
- De Cristofaro, R.; De Candia, E.; Rutella, S.; Weitz, J.I.. "The Asp272-Glu282 region of platelet glycoprotein IBa interacts
with the heparin-binding site of a-thrombin and protects the enzyme from the heparin-catalyzed inhibition by antithrombin
III". Journal of Biological Chemistry 275 6 (2000): 3887-3895. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034635224&partnerID=MN8TOARS.
10.1074/jbc.275.6.3887
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of autologous peripheral CD34+ cells: Analysis of predictive factors and comparison with unselected progenitor transplants".
British Journal of Haematology 108 1 (2000): 105-115. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033963020&partnerID=MN8TOARS.
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p27 in human primitive proliferating hematopoietic progenitors by autocrine TGF-ß1 is a cell cycle-independent effect and
influences their hematopoietic potential". Blood 95 10 (2000): 3001-3010. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034657830&partnerID=MN8TOARS.
- Rutella, S.; Rumi, C.; Pierelli, L.; Morosetti, R.; Sica, S.; Bonanno, G.; Scambia, G.; Leone, G.. "Granulocyte colony-stimulating
factor perturbs lymphocyte mitochondrial function and inhibits cell cycle progression". Experimental Hematology 28
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10.1016/S0301-472X(00)00164-8
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by recombinant human granulocyte colony-stimulating factor (rHuG-CSF) (multiple letters)". British Journal of Cancer
82 9 (2000): 1610-1611. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034113545&partnerID=MN8TOARS.
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of cyclin-dependent kinase inhibitor p15(INK4B) during normal and leukemic myeloid differentiation". Experimental Hematology
28 5 (2000): 519-526. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034104765&partnerID=MN8TOARS.
10.1016/S0301-472X(00)00139-9
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to apoptosis in T cells recovering after autologous peripheral blood progenitor cell transplantation: Reversal by interleukin-15".
Cytokines, Cellular and Molecular Therapy 6 4 (2000): 189-198. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034431926&partnerID=MN8TOARS.
- Rutella, S.; Plerelli, L.; Bonanno, G.; Scambla, G.; Leone, G.; Rumi, C.. "Homogeneous expression of CXC chemokine receptor
4 (CXCR4) on G-CSF- mobilized peripheral blood CD34+ cells [2]". Blood 95 12 (2000): 4015-4016. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034660404&partnerID=MN8TOARS.
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kinase inhibitors in Bcl-2 and Bcl-x(L)-expressing CD34+-proliferating haematopoietic progenitors". British Journal of
Haematology 110 3 (2000): 654-662. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033777115&partnerID=MN8TOARS.
10.1046/j.1365-2141.2000.02227.x
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(CD36) in B-cell chronic lymphocytic leukemia as an indicator of tumor cell dissemination". Haematologica 84 5 (1999):
419-424. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032874826&partnerID=MN8TOARS.
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CD69 antigen on normal CD4+ and CD8+ lymphocyte subsets and its relationship with the phenotype of responding T-cells". Communications
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10.1002/(SICI)1097-0320(19990615)38:3<95::AID-CYTO1>3.0.CO;2-L
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lymphocyte phenotype and function". Journal of Interferon and Cytokine Research 19 9 (1999): 989-994. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032864809&partnerID=MN8TOARS.
10.1089/107999099313181
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