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Dr. Tiago Dantas is an Assistant/Auxiliary Investigator at the i3S (Instituto de Investigação e Inovação em Saúde), supported by a CEEC contract from FCT (ending in 02-2025). He has published 22 manuscripts in peer-reviewed, internationally renowned journals (including Nature Communications, Developmental Cell, Journal of Cell Biology and Cell Reports), 8 of which as a first or co-first author, and 9 as the corresponding or co-corresponding author. His publications have a total of 704 citations and an h-index of 14. Dr Dantas started his scientific career as an Erasmus student investigating centrosome biology in the lab of Prof Ciaran Morrison at the National University of Ireland in Galway. He was then awarded a fellowship from FCT to continue his work in Prof Morrison's lab as a PhD student in 2008. His dissertation focused on the crosstalk between centrosomal proteins and the DNA damage response. After receiving his PhD in Ireland in 2012, Dr Dantas joined the lab of Prof Richard Vallee at Columbia University in New York, USA, where he was funded by the AHA/ASA to study the importance of ciliogenesis and molecular motors in neural stem cell proliferation. In addition, he studied the involvement of Dyneins in human disease. In 2018, Dr Dantas joined IBMC/i3S to start his own line of research funded by FCT. His lab is interested in: A) uncovering cilia-dependent mechanisms that regulate cell cycle progression and proliferation of neural stem cells during brain development; and B) dissecting the underlying causes for the severe cases of Dynein-2-associated skeletal ciliopathies. Throughout his career, Dr Dantas has supervised many students (6 PhD plus 7 Master students, see extended CV for details) and postdocs (Dr. Carla Abreu, Dr. José B Gama and Dr. Sónia Rocha at i3S). He also mentored junior Post-docs and PhD students while in the Vallee lab. He was Examiner in the defense of 1 Undergraduate, 9 Master and 2 PhD theses. He is also an editorial board member of the Communications Biology (Nat. group) and Frontiers in Cellular Neuroscience journals. He edited and organized the "Centrosomes and Cilia" special collection at Communications Biology (Nature PG). 2021: https://www.nature. com/collections/iadheaabic During the last 5 years at i3S, Dr. Dantas was the corresponding author of 3 research articles detailing major breakthroughs in understanding ciliary transport (including a Cell Rep and a JCB that received 1 cover and 1 highlight by experts), 4 review/editorial articles (3 of them as corresponding author), alongside 3 collaborative studies (1 as pre-print, currently under review in JCB; and a Dev Cell that was also awarded the cover; see below for details).
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Identificação

Identificação pessoal

Nome completo
Tiago Jorge Oliveira Gonçalves de Almeida Dantas

Nomes de citação

  • Dantas TJ

Identificadores de autor

Ciência ID
D910-6CF5-834D
ORCID iD
0000-0002-0120-4895

Moradas

  • Institute for Research and Innovation in Health (i3S), Rua Alfredo Allen, 208, 4200-135, Porto, Porto, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Naturais - Ciências Biológicas - Biologia do Desenvolvimento
  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Formação
Grau Classificação
2018/05
Concluído
 Course in Laboratory Animal Science accredited by FELASA following the recommendations for Category C (Outros)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2017/03 - 2017/12
Concluído
 Associate Research Scientist in the lab of Prof. Richard Vallee (NY, USA) (Outros)
Columbia University Irving Medical Center, Estados Unidos
2012/07 - 2017/02
Concluído
 Postdoctoral Researcher in the lab of Prof. Richard Vallee (NY, USA) (Pós-doutoramento)
Columbia University Department of Pathology and Cell Biology, Estados Unidos
2008/01 - 2012/10
Concluído
 PhD in Biochemistry and Cell Biology in Prof. Ciaran Morrison's Lab (Doutoramento)
National University of Ireland Galway, Irlanda
"The Roles of Centrins at the Centrosome and in Genome Maintenance" (TESE/DISSERTAÇÃO)
 Thesis defended and approved without corrections
2012/01 - 2012/01
Concluído
 Selected for internship (during PhD) to perform collaborative work under the Euro-BioImaging Proof-of-Concept program in the laboratory of Prof. Elisa Ferrando-May (Outros)
Universität Konstanz, Alemanha
2003/09 - 2007/12
Concluído
 Applied Biology Degree (Graduated in the top 5) (Licenciatura)
Universidade do Minho Departamento de Biologia, Portugal
 16/20
2007/02 - 2007/07
Concluído
 Undergraduate Final Year Lab Project (Erasmus Program) (Licenciatura)
National University of Ireland Galway, Irlanda
"Development of an inducible DNA double strand break system" (TESE/DISSERTAÇÃO)
 18/20
2005/07 - 2005/07
Concluído
 Voluntary summer project: Treatment of an effluent with halotolerant yeasts, under the supervision of Prof. Isabel Mina (Outros)
Universidade do Minho, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2018/01/10 - Atual Investigador Auxiliar (carreira) (Investigação) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Projetos

Bolsa

Designação Financiadores
2025/04/01 - Atual (Under Evaluation) Zooming into cilia: modeling patient variants to decode inherited retinal disorders pathogenicity and therapeutic insights
eyeCilia
Investigador responsável
Em avaliação
2025/01/01 - Atual Dissecting novel mechanisms governing retrograde transport inside cilia by a ciliopathy-associated kinase (the PI of the Project is a member on my Research Team)
2023.12458.PEX
Orientador
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2023/01/01 - Atual Dissecting the mechanisms regulating the essential roles of the Dynein-2 motor in cilia
2022.01955.PTDC
Investigador responsável
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2023/01/01 - Atual Investigating the drivers of Fanconi Anemia-associated brain malformations (PI is a member of my Research Team)
2022.01964.PTDC
Orientador
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018/07 - 2022/03 Investigating the molecular causes of severe Microcephaly: Primary cilium dependent cell cycle control of neural stem cell proliferation during brain development (POCI grant)
POCI-01-0145-FEDER-029471
Investigador responsável
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Concluído
2015/07 - 2017/06 A Role for Centrosome Positioning in Controlling Neural Progenitor Division
15POST25080068
 American Heart and Stroke Associations
2008/01 - 2011/12 The Roles of Centrins at the Centrosome and in Genome Maintenance
SFRH / BD / 40940 / 2007
 Foundation for Science and Technology, Portugal

Projeto

Designação Financiadores
2019/04 - Atual Primary cilium-dependent cell cycle control of neural stem cell proliferation (FCT CEEC grant)
CEECIND/00771/2017
Investigador responsável
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
Produções

Publicações

Artigo em jornal
  1. "Investigadores portugueses descobrem uma das causas de malformações embrionárias de algumas doenças genéticas", CNN Portugal, 2021, https://bit.ly/3H5rMUr.
  2. "Descoberta uma das causas de malformações embrionárias de algumas doenças genéticas", Diario de Noticias (DN), 2021, https://bit.ly/3I3P7Hq.
  3. "Descoberta uma das causas de malformações embrionárias de algumas doenças genéticas", Observador, 2021, https://bit.ly/3v4CSXu.
Artigo em revista
  1. DANTAS, TIAGO J ; Abreu, Carla M. C.; De-Castro, Maria J. G.; Grosso, Ana Rita; de Sousa Valente, Joao; da Silva Xavier, Gabriela. "25 de Abril Sempre! Portuguese Science and the 50th anniversary of the Carnation Revolution". Communications Biology 7 1 (2024): http://dx.doi.org/10.1038/s42003-024-06229-y.
    10.1038/s42003-024-06229-y
  2. Francisco Gonçalves-Santos; Ana R.G. De-Castro; Diogo R.M. Rodrigues; Maria J.G. De-Castro; Reto Gassmann; Carla M.C. Abreu; TIAGO J DANTAS#. "Hot-wiring dynein-2 establishes roles for IFT-A in retrograde train assembly and motility". Cell Reports (2023): https://doi.org/10.1016/j.celrep.2023.113337.
    10.1016/j.celrep.2023.113337
  3. Francisco Gonçalves-Santos; Maria J. G. De-Castro; Ana R. G. De-Castro ; TIAGO J DANTAS#. Autor correspondente: TIAGO J DANTAS#. "Building train carriages for ciliary transport: (IFT-)A complex task". Communications Biology 6 1 (2023): http://dx.doi.org/10.1038/s42003-023-04426-9.
    10.1038/s42003-023-04426-9
  4. Ana R. G. De-Castro*; Diogo R. M. Rodrigues*; Maria J. De-Castro; Neide Vieira; Cármen Vieira; Ana X. Carvalho; Reto Gassmann; Carla M. C. Abreu#; TIAGO J DANTAS#. Autor correspondente: TIAGO J DANTAS#. "WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing". Journal of Cell Biology 221 1 (2022): https://bit.ly/3oY6nq4.
    10.1083/jcb.202010178
  5. Carla M. Abreu#; TIAGO J DANTAS#. Autor correspondente: TIAGO J DANTAS#. "Coping with centriole loss: pericentriolar material maintenance after centriole degeneration". Communications Biology 4 1 (2021): http://dx.doi.org/10.1038/s42003-021-02243-6.
    10.1038/s42003-021-02243-6
  6. Ana R. G. De-Castro*; Joana Quintas-Gonçalves*; Tiago Ribeiro-Silva ; Diogo R. M. Rodrigues ; Maria J. De-Castro; Carla M. C. Abreu#; TIAGO J DANTAS#. Autor correspondente: TIAGO J DANTAS#. "The IFT20 homolog in Caenorhabditis elegans is required for ciliogenesis and cilia-mediated behavior". microPub Biology (2021): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114103/pdf/25789430-2021-micropub.biology.000396.pdf.
    10.17912/micropub.biology.000396
  7. TIAGO J DANTAS#. Autor correspondente: TIAGO J DANTAS#. "Centrosomes and cilia: always at the center of the action". Communications Biology 3 1 (2020): http://dx.doi.org/10.1038/s42003-020-01519-7.
    10.1038/s42003-020-01519-7
  8. Noopur V. Khobrekar; Sebastian Quintremil; TIAGO J DANTAS; Richard B. Vallee. "The Dynein Adaptor RILP Controls Neuronal Autophagosome Biogenesis, Transport, and Clearance". Developmental Cell 53 2 (2020): 141-153.e4. http://dx.doi.org/10.1016/j.devcel.2020.03.011.
    10.1016/j.devcel.2020.03.011
  9. João Carlos Gonçalves; TIAGO J DANTAS; Richard B. Vallee. "Distinct roles for dynein light intermediate chains in neurogenesis, migration, and terminal somal translocation". The Journal of Cell Biology (2019): jcb.201806112-jcb.201806112. https://doi.org/10.1083/jcb.201806112.
    10.1083/jcb.201806112
  10. Ana Luisa Rodrigues Toste de Carvalho; Alexandros Strikoudis; Hsiao-Yun Liu; Ya-Wen Chen; TIAGO J DANTAS; Richard B. Vallee; Jorge Correia-Pinto; Hans-Willem Snoeck. "Glycogen synthase kinase 3 induces multilineage maturation of human pluripotent stem cell-derived lung progenitors in 3D culture". Development 146 2 (2018): dev171652. http://dx.doi.org/10.1242/dev.171652.
    10.1242/dev.171652
  11. TIAGO J DANTAS (co-corresponding author); Aurelie Carabalona; Daniel Jun Kit Hu; Richard B. Vallee. "Emerging roles for motor proteins in progenitor cell behavior and neuronal migration during brain development". Cytoskeleton 73 10 (2016): Spc1-Spc1. https://doi.org/10.1002%2Fcm.21337.
    10.1002/cm.21337
  12. David J. Doobin; TIAGO J DANTAS (co-corresponding author); Richard B. Vallee. "Microcephaly as a cell cycle disease". Cell Cycle 16 3 (2016): 247-248. https://doi.org/10.1080%2F15384101.2016.1252591.
    10.1080/15384101.2016.1252591
  13. David J. Doobin*; Shahrnaz Kemal*; TIAGO J DANTAS*; Richard B. Vallee. "Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages". Nature Communications 7 (2016): 12551-12551. https://doi.org/10.1038%2Fncomms12551.
    10.1038/ncomms12551
  14. Owen M. Daly; David Gaboriau; Kadin Karakaya; Sinéad King; TIAGO J DANTAS; Pierce Lalor; Peter Dockery; Alwin Krämer; Ciaran G. Morrison. "CEP164-null cells generated by genome editing show a ciliation defect with intact DNA repair capacity". Journal of Cell Science 129 9 (2016): 1769-1774. https://doi.org/10.1242%2Fjcs.186221.
    10.1242/jcs.186221
  15. S. Paige Taylor*; TIAGO J DANTAS*; Ivan Duran; Sulin Wu; Ralph S. Lachman; Michael J. Bamshad; Jay Shendure; et al. "Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome". Nature Communications 6 (2015): 7092-7092. https://doi.org/10.1038%2Fncomms8092.
    10.1038/ncomms8092
  16. TIAGO J DANTAS; Owen M. Daly; Pauline C. Conroy; Martin Tomas; Yifan Wang; Pierce Lalor; Peter Dockery; et al. "Calcium-Binding Capacity of Centrin2 Is Required for Linear POC5 Assembly but Not for Nucleotide Excision Repair". PLoS ONE 8 7 (2013): e68487-e68487. https://doi.org/10.1371%2Fjournal.pone.0068487.
    10.1371/journal.pone.0068487
  17. Yifan Wang; TIAGO J DANTAS; Pierce Lalor; Peter Dockery; Ciaran G. Morrison. "Promoter hijack reveals pericentrin functions in mitosis and the DNA damage response". Cell Cycle 12 4 (2013): 635-646. https://doi.org/10.4161%2Fcc.23516.
    10.4161/cc.23516
  18. Pauline C. Conroy; Chiara Saladino; TIAGO J DANTAS; Pierce Lalor; Peter Dockery; Ciaran G. Morrison. "C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis". Cell Cycle 11 20 (2012): 3769-3778. https://doi.org/10.4161%2Fcc.21986.
    10.4161/cc.21986
  19. TIAGO J DANTAS; Owen M. Daly; Ciaran G. Morrison. "Such small hands: the roles of centrins/caltractins in the centriole and in genome maintenance". Cellular and Molecular Life Sciences 69 18 (2012): 2979-2997. https://doi.org/10.1007%2Fs00018-012-0961-1.
    10.1007/s00018-012-0961-1
  20. TIAGO J DANTAS; Yifan Wang; Pierce Lalor; Peter Dockery; Ciaran G. Morrison. "Defective nucleotide excision repair with normal centrosome structures and functions in the absence of all vertebrate centrins". The Journal of Cell Biology 193 2 (2011): 307-318. https://doi.org/10.1083%2Fjcb.201012093.
    10.1083/jcb.201012093
Capítulo de livro
  1. Julie Yi; Noopur V. Khobrekar; TIAGO J DANTAS; Jie Zhou; Richard B. Vallee. "Imaging of motor-dependent transport in neuronal and nonneuronal cells at high spatial and temporal resolution". In The Neuronal Cytoskeleton, Motor Proteins, and Organelle Trafficking in the Axon, 453-465. Elsevier, 2016.
    10.1016/bs.mcb.2015.06.014
  2. Alexandre D. Baffet*; Aurélie Carabalona*; TIAGO J DANTAS*; David D. Doobin; Daniel J. Hu; Richard B. Vallee. "Cellular and subcellular imaging of motor protein-based behavior in embryonic rat brain". In The Neuronal Cytoskeleton, Motor Proteins, and Organelle Trafficking in the Axon, 349-363. Elsevier, 2016.
    10.1016/bs.mcb.2015.06.013
Recurso online
  1. Teixeira, Vanessa; Singh, Kashish; Gama, José B.; Celestino, Ricardo; Carvalho, Ana Xavier; Pereira, Paulo; Abreu, Carla M.C.; et al. Autor correspondente: Gassmann, Reto. CDR2 is a dynein adaptor recruited by kinectin to regulate ER sheet organization (pre-print). 2024. http://dx.doi.org/10.1101/2024.11.06.622207.
    10.1101/2024.11.06.622207
  2. TIAGO J DANTAS. Edited and organized the "Centrosomes and Cilia" special collection at Communications Biology (Nature PG). 2021. https://www.nature.com/collections/iadheaabic.
Tese / Dissertação
  1. Dantas, Tiago. "The roles of centrins/caltractins at the centrosome and in genome maintenance.". Doutoramento, National University of Ireland Galway, 2012. https://aran.library.nuigalway.ie/handle/10379/5064.

Outros

Outra produção
  1. Cover selected for issue at Journal of Cell Biology. 2022. Maria J. De-Castro; Carla M. C. Abreu; TIAGO J DANTAS. https://rupress.org/jcb/issue/221/1.
  2. Cover selected for issue at Developmental Cell. 2020. Noopur V. Khobrekar; TIAGO J DANTAS; Richard B. Vallee. https://www.cell.com/developmental-cell/issue?pii=S1534-5807(19)X0009-X#.
  3. Image selected for Cover of special issue at Cytoskeleton. 2016. TIAGO J DANTAS. https://onlinelibrary.wiley.com/toc/19493592/2016/73/10.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/11/01 Invited for Round Table Discussion: "Genetic Modification of Embryos" at the XVII Minho Medical Meeting XVII Minho Medical Meeting
University of Minho (Braga, Portugal)
2023/10/16 Hot-wiring dynein-2 establishes roles for IFT-A in retrograde train assembly and motility 12th Meeting on Cilia, Flagella and Centrosomes
(Marseille, França)
2023/09/29 Invited to participate in Round Table Discussion: "Young Leaders in Investigation-Funding Opportunities" at the Global Health Forum 2023, organized by a prior Health Minister of Portugal Global Health Forum 2023
(Lisbon, Portugal)
2023/07/12 Hot-wiring dynein-2 uncovers roles for IFT-A in retrograde train assembly and motility Motors in Quarantine talks
Prof. Anne Straube (Reino Unido)
2022/03/16 Dissecting the mechanisms regulating the essential roles of the Dynein-2 motor in cilia. LYSOCIL CEDOC-NMS I FCM special seminar
Dr. Susana Lopes (Lisbon)
2021/11/16 WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing 35th BSCB GenSoc UK Cilia Network e-symposium
(Reino Unido)
2021/09/16 WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing VU University, Amsterdam
Prof. Erwin Peterman (Países Baixos)
2021/09 Short presentation on: WDR60-mediated dynein-2 loading into cilia is critical for retrograde IFT and transition zone crossing Dynein 2021
(Reino Unido)
2019/09/30 Dyneins: molecular motors critical for neurodevelopment One day meeting on Neurobiology and Neurological Disorders - Discoveries CTR
i3S (Portugal)
2018/08 Cytoplasmic Dyneins: linking molecular motors to human diseases Francis Crick Institute
Dr. Thomas Surrey (Reino Unido)
2018/01 Cytoplasmic Dyneins: linking molecular motors to human diseases XIX edition of the Applied Biology Seminars, Minho University
Organizing committee (Braga, Portugal)
2017/12 Cytoplasmic Dyneins: linking molecular motors to human diseases Columbia Stem Cell Seminars
Columbia Stem Cell Initiative (CSCI) (Estados Unidos)
2016/12/19 Cytoplasmic Dyneins: linking molecular motors to human diseases Instituto de Investigação e Inovação em Saúde (i3S)
Dr. Monica Sousa (Porto, Portugal)
2014/12 Primary cilium-dependent cell cycle control of neural stem cell proliferation during brain development Instituto Gulbenkian de Ciência (IGC) seminar
Dr. Monica Bettencourt-Dias (Oeiras, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2024/01/01 - Atual Dissecting the mechanisms mediating Dynein-2 incorporation into cilia and their implications for ciliopathies
Coorientador de Maria João G. De-Castro
 PhD in Animal Science (Doutoramento)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/01/01 - Atual Dissecting the mechanisms of ciliary gating: interplay between Dynein-2 and the transition zone
Orientador de Ana Rita Gonçalves De Castro (UI/BD/152865/2022)
 PhD in Molecular and Cell Biology (Doutoramento)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/10/01 - Atual Dissecting the NDE1/LIS1-dependent regulation of Dynein-mediated transport in the brain
Orientador de Tiago Xavier Ribeiro (2021.04761.BD)
 PhD Biomedical Sciences (ICBAS, UP) (Doutoramento)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/11/01 - Atual Uncovering the mechanisms regulating the essential roles of Dynein-2 in cilia function
Orientador de Diogo Rafael Marques Rodrigues (SFRH/BD/143985/2019)
 PhD Biomedical Sciences (ICBAS, UP) (Doutoramento)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/10/01 - Atual Functional analysis of novel cargo adaptors for the molecular motor cytoplasmic Dynein-1
Coorientador de Vanessa Alves Teixeira
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/02 - 2023/10/26 Recruitment and loading of Dynein-2 into cilia to ensure signaling functions
Orientador de Luisa de Sousa Fonseca
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Faculdade de Medicina, Portugal
2023/02/06 - 2023/10/09 Investigating a role for the IFT- A complex in the recruitment of molecular motors to neuronal cilia
Orientador de Francisca Bryant-Jorge Dias
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/05 - 2022/10/12 Investigating the regulation of Dynein-2 during cilia-mediated signaling (final score 20/20)
Orientador de Francisco Gonçalves Santos
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/09/01 - 2022/09/30 "Summer with Science", funded by FCT - Foundation for Science and Technology
Orientador de Mariana Sousa
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/06 - 2021/08 Volunteer Internship
Orientador de Maria João G. De-Castro
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/06/14 - 2020/12/02 Ciliary recruitment of the dynein-2 motor and its role in C. elegans sensory functions (final score 20/20)
Orientador de Ana Rita Gonçalves de Castro
 Master in Biomedical Sciences (Mestrado)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018/03 - 2019/11/04 Dissecting the molecular causes of NDE1-associated microcephaly (final score 19/20)
Orientador de Cármen Maria Leal Vieira
 Neurobiology (Mestrado)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018/03/14 - 2018/07/31 Understanding the importance of Dynein-2 in cilia function and its involvement in human diseases
Orientador de Telma Sofia Mota Oliveira (18/19)
 Anatomia Patológica, Citológica e Tanatológica (Licenciatura/Bacharelato)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2012 - 2017 Novel Functions for Dynein Adaptor RILP in Neuronal Autophagy (co-supervisor)
Coorientador de Noopur V. Khobrekar
Columbia University Irving Medical Center, Estados Unidos

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2024/09/12 - 2024/09/12 Invited to Co-Chair the session of "Intraciliary transport and Intraflagellar transport" at the 4-day, European Cilia 2024 Meeting in Dublin (2024/09/10)
Encontro (Outra)
 University College Dublin College of Science, Irlanda
2023 - 2024 Co-organizer of several outreach workshops engaging with high school students as part of National educational programs (such as project “SEI” - Sociedade, Escola e Investigação) and "Brain Week" at i3S and in Public Schools (2023/09 - 2024/06)
Oficina (workshop) (Membro da Comissão Organizadora)
 Câmara Municipal do Porto, Portugal
2023/03/13 - 2023/03/17 Coordinator of a scientific exhibition of the C. elegans nervous system for high-school students (7th to 9th grade) as part of the International Brain Week 2023. (2023/03/13 - 2023/03/17)
Exposição (Coorganizador)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2010/03/14 - 2010/06/19 Instructor for an EMBO practical course: The DT40 cell line as a model vertebrate genetic system (2010/06/14 - 2010/06/19)
Oficina (workshop) (Outra)
 National University of Ireland - Galway National Centre for Biomedical Engineering Science, Irlanda
2005/11 - 2006/11 Treasurer and Organizer of the VIII Seminars (Jornadas) of Applied Biology (2006/11)
Conferência (Membro da Comissão Organizadora)
 Universidade do Minho, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2024/12/10 Targeting EGFR to Modulate Primary Cilia in Prostate Cell Lines Harbouring ETS Rearrangements
Arguente principal
 Sofia de Oliveira Costa (Mestrado)
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2024/11/04 Caenorhabditis elegans as a model to study gene function – identification of genetic modifiers in a C. elegans model of Machado-Joseph disease (MJD)
Arguente principal
 Leonor de Macedo Martins (Mestrado)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2023/10/13 Understanding the Mechanisms of Axonal Adaptation to Physiological Tension
Arguente principal
 Rita Gonçalves Bessa (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/11/23 The interplay between the clustering of basolateral proteins and the organization of the microtubule cytoskeleton in epithelial cells
Arguente principal
 Mariana Gadelho Gonçalves (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/10/12 Evaluation of the work carried out during the probationary year of her PhD: "Comprehensive Dissection of the Interplay between the Tubulin Code and Chromosomal Instability during Mitosis"
Arguente principal
 Joana Filipe Gomes Araújo Macário Monteiro (Outro)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/07/21 Disruption of Ezrin in airway epithelial cell culture affects ciliary dynamics
Arguente principal
 Carlos Filipe Hurtado Serra (Mestrado)
Universidade do Minho, Portugal
2020/01/08 The Hippo/Notch interplay in early chick lung development
Arguente principal
 Carla Sofia Gonçalves (Mestrado)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/11/20 Identification of Novel Conserved Dynein Pathway Genes Using a Genome-wide Synthetic Lethal Screen in C. elegans
Arguente
 Helder Henrique Ribeiro Rocha (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/10/07 Pathogenic variants in movement disorders: modifiers, interactors and disease models
Arguente
 Conceição Pereira (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/01/04 Effect of serotonergic signaling activation in proteostasis modulating using C elegans
Arguente principal
 José Luís de Barros Ferreira Duarte Raposo (Mestrado)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/01/04 Chick lung branching morphogenesis: Hippo’s role and its modulation by Dobutamine
Arguente principal
 Gonçalo Ribeiro Miranda (Mestrado)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/11/27 Dissecting the Role of Caenorhabditis elegans Dynein Light Intermediate Chain in Neuronal Trafficking
Arguente principal
 Cátia Filipa Vieira de Carvalho (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal

Arbitragem científica em conferência

Nome da conferência Local da conferência
2020/08 - 2020/10 3rd PhDay | Back to the Future i3S - Instituto de Investigação e Inovação em Saúde in Porto

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2020/05 - Atual Editorial Board Member of Frontiers in Cellular Neuroscience Frontiers Publications
2018/10 - Atual Editorial Board Member of Communications Biology (2399-3642) Nature/ Springer Science and Business Media LLC

Comissão de avaliação

Descrição da atividade
Tipo de assessoria 		Instituição / Organização Entidade financiadora
2022/10 - 2022/12 Selected as an expert by the EU Commission to evaluate 6x MSCA-PF-2022 grant applications
Avaliador
 European Commission Marie Sklodowska-Curie Actions, Bélgica European Commission Marie Sklodowska-Curie Actions
2021/10 - 2021/12 Selected as an expert by the EU Commission to evaluate 10x MSCA-PF-2021 grant applications
Avaliador
 European Commission Marie Sklodowska-Curie Actions, Bélgica European Commission Marie Sklodowska-Curie Actions

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2022 - Atual Class on "Caenorhabditis elegans as a model organism in Biomedical Reasearch" part of the course Advanced Research Methods for Biomedical Master students Investigação Biomédica (Mestrado integrado) Universidade Nova de Lisboa Medical School, Portugal
2019/10 - Atual Class on Neurodevelopment for the Master students in Neurobiology (Curso de Especialização Tecnológica) Universidade do Porto Faculdade de Medicina, Portugal
2008/09 - 2010/06 Demonstrator in practical classes for the Biochemistry and Medicine degrees Biochemistry (Licenciatura) National University of Ireland Galway, Irlanda

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2022/01/21 Invited interview about molecular motors and their future applications in combination with nanotechnological approaches, entitled "Nanorrobôs prontos para invadir o corpo humano" Jornal Expresso

Membro de associação

Nome da associação Tipo de participação
2012 - 2017 American Society for Cell Biology
2005/04 - 2006/11 President of the Fiscal and Jurisdictional Council of the Applied Biology Student Association President

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2019/11/06 - Atual Invited to be a Member of the Committee responsible for evaluating the posters presentated at the MCBiology PhD 6th edition, Porto Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Distinções

Prémio

2024 "Best Oral Presentation" received by one of my PhD Students (Ana De-Castro) at the Cilia2024 meeting
2019 FCT Scientific Employment (CEEC) grant (6-Years)
Fundação para a Ciência e a Tecnologia, Portugal
2015 Postdoctoral fellowship award from AHA/ASA (American Heart/ Stroke Associations)
American Heart and Stroke Associations , Estados Unidos
2010 Scholarship award to attend the workshop "The Centrosome: Structure, Function and Dynamics"
2008 FCT Doctoral fellowship award (4-Years)
Fundação para a Ciência e a Tecnologia, Portugal
2007 Erasmus scholarship award
European Commission, Bélgica