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I am a senior researcher and the coordinator of the CHAIN biobank at the NMS-UNL. I hold a Bachelor of Engineering in Biomedical Materials Science & Engineering and a Ph.D. in Biomaterials from Queen Mary University of London (sponsored by Johnson&Johnson, UK), where I investigated alternative radiopacity for orthopaedic cements during total hip replacement surgeries. I was awarded a prestigious Marie Curie fellowship to conduct research on cemented hip arthroplasty at the Orthopaedics department of Lund University Hospital (Sweden), where I worked within a multidisciplinary team of orthopaedic surgeons, biomaterials scientists and biologists. During this period, I supervised and co-supervised master¿s and Ph.D. students, collaborated with orthopaedic companies in Scandinavia and academic partners at Aarhus University (Denmark) on joint research projects, all of which yielded high-quality publications in peer-reviewed international journals. Post Marie Curie, I focused my research on the optimization of biomaterials for vertebroplasty (Bupa funding) at the Centre for Orthopaedic Biomechanics, University of Bath, UK. Then moved to Lisbon and worked at the Rheumatology research unit at Instituto de Medicina Molecular where I investigated the nanostructural properties of osteoporotic bone in a mouse model, winning the prestigious European Calcified Tissue Society award. This research project marked the beginning of my independent research path as a PI. Currently, I´m the coordinator of the CHAIN Biobank at NOVA Medical School, UNL, responsible for its implementation and functioning and an integrated researcher at CHRC, NMS, UNL.
Identificação

Identificação pessoal

Nome completo
Saba Abdulghani

Nomes de citação

  • Saba Abdulghani

Identificadores de autor

Ciência ID
E319-65B5-8402
ORCID iD
0000-0003-4537-8691
Scopus Author Id
16314729600

Moradas

  • Rua do Instituto Bacteriológico, nº5 , 1150-082 , Lisboa, Lisboa, Portugal (Profissional)

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Engenharia dos Materiais - Engenharia dos Materiais
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais
  • Ciências Médicas e da Saúde
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Árabe (Idioma materno)
Inglês (Idioma materno)
Sueco Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2022/02/21 - 2022/03/08
Em curso
Ready for BioData Management?: Data Stewardship for Life Sciences Training Program (Outros)
Especialização em BioData Management
BioData.pt, Portugal
2021/11/13 - 2021/11/27
Concluído
PRE-ANALYTICAL PHASES OF BIOBANKING (Outros)
Especialização em PRE-ANALYTICAL PHASES OF BIOBANKING
BBMRI-ERIC, Áustria
2020/04/01 - 2020/06/01
Concluído
Essentials of Biobanking Course (Outros)
Especialização em Biobanking
The University of British Columbia, Canadá

International Society for Biological and Environmental Repositories, Canadá
2018/10/01 - 2018/10/02
Concluído
Workshop on Infrared Microspectroscopy applications in biomedical research (Outros)
Especialização em Infrared Microspectroscopy-Synchrotron
ALBA Synchrotron, Espanha
1999/09/20 - 2003/05/01
Concluído
Biomedical Materials Sciences (Doctor of Philosophy)
Queen Mary University of London, Reino Unido
1996/01/09 - 1999/06/25
Concluído
Biomedical Materials Science and Engineering (Bachelor)
Especialização em Biomaterials
Queen Mary University of London - Mile End Campus, Reino Unido
2:I
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2020/02/01 - Atual Pós-doutorado (Investigação) Universidade Nova de Lisboa Comprehensive Health Research Centre, Portugal
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
2018/01/11 - 2020/01/10 Investigador Contratado (Investigação) Instituto Politécnico de Leiria Centro para o Desenvolvimento Rápido e Sustentado de Produto, Portugal
2010/11/24 - 2013/05/24 Pós-doutorado (Investigação) Instituto de Medicina Molecular, Portugal
Instituto de Medicina Molecular, Portugal
2006/07/01 - 2007/11/20 Investigador Auxiliar (carreira) (Investigação) University of Bath Department of Mechanical Engineering, Reino Unido

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2020/09/01 - Atual Biobank Coordinator Universidade Nova de Lisboa Comprehensive Health Research Centre, Portugal
Universidade Nova de Lisboa Comprehensive Health Research Centre, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2008/02/01 - 2009/02/01 Post-doctoral researcher Instituto de Medicina Molecular, Portugal
2003/06/01 - 2006/06/20 Marie Curie Research Fellow: A Study of the Factors Determining Penetration of Polymethyl Methacrylate Bone Cement into Trabecular Bone: biomaterials and biomechanics Lunds Universitet, Suécia
Projetos

Bolsa

Designação Financiadores
2022/01/01 - 2023/12/31 The effects of whole-body vibration (WBV) on the management of osteoporosis in early menopausal women (INTENSE)
CHRC -UID/04923/2020
Investigador responsável
Universidade Nova de Lisboa Comprehensive Health Research Centre, Portugal
Universidade Nova de Lisboa Comprehensive Health Research Centre Escola Nacional Saúde Pública
Em curso
2022/05/03 - 2022/05/06 Using SAXS to investigate the effects of early menopause on the nanostructural properties of osteoporotic bone
2021095457
Investigador responsável
Universidade Nova de Lisboa Comprehensive Health Research Centre, Portugal
ALBA Synchrotron
Em curso
2020/02/04 - 2020/02/05 Exploiting Small-angle X-ray Scattering at ALBA to understand osteoporotic bone nanostructure and to enable the next generation of scaffolds for bone tissue generation
2019093949
Investigador responsável
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
ALBA Synchrotron
Concluído
2019/03/19 - 2019/03/20 Exploiting Small-angle X-ray Scattering at ALBA to understand bone microstructure and to enable the next generation of scaffolds for bone tissue generation
2018093021
Investigador responsável
Instituto Politécnico de Leiria Centro para o Desenvolvimento Rápido e Sustentado de Produto, Portugal
ALBA Synchrotron
Concluído
2019/02/27 - 2019/03/02 Exploiting Infra-Red Spectroscopy at ALBA to understand bone microstructure and to enable the next generation of scaffolds for bone tissue generation
2018093100
Investigador responsável
Instituto Politécnico de Leiria Centro para o Desenvolvimento Rápido e Sustentado de Produto, Portugal
ALBA Synchrotron
Concluído
2018/12/01 - 2019/01/11 biomaterials from nature (fromNature)
C518186118-00111256
Investigador responsável
Instituto Politécnico de Leiria Centro para o Desenvolvimento Rápido e Sustentado de Produto, Portugal
Em curso

Outro

Designação Financiadores
2021/03/11 - 2021/03/12 Using SAXS to investigate the effects of early menopause on the nanostructural properties of osteoporotic bone
2020094595
Investigador responsável
Universidade Nova de Lisboa Comprehensive Health Research Centre, Portugal
ALBA Synchrotron
Em curso
Produções

Publicações

Artigo em conferência
  1. Abdulghani, S.; Kjellson, F.; Behiri, J.C.. "Physical and radiopaque characterisation of acrylic bone cements containing an organobismuth compound as a radiopacifier". 2004.
  2. Kjellson, F.; Brudeli, B.; Abdulghani, S.; McCarthy, I.. "Mechanical properties of an acrylic bone cement with a monomer soluble contrast media". 2004.
  3. Abdulghani, S.; Behiri, J.C.. "Static mechanical properties of acrylic bone cements containing an organobismuth compound as a radiopacifier". 2004.
Artigo em revista
  1. Lopes, David G.; Henriques, Ana Rita; Santos-Dias, Margarida; Nunes-da-Silva, Catarina; Gonçalves, Juliana; de Sousa, Rute D.; Abdulghani, Saba; et al. "Staff SARS-CoV-2 Seroprevalence and Mental Health as Key Factors in University Response to COVID-19 Pandemic". Frontiers in Public Health 9 (2021): http://dx.doi.org/10.3389/fpubh.2021.689919.
    Acesso aberto • Publicado • 10.3389/fpubh.2021.689919
  2. Abdulghani, Saba; Mitchell, Geoffrey R.. "Biomaterials for In Situ Tissue Regeneration: A Review". Biomolecules 9 11 (2019): 750. http://dx.doi.org/10.3390/biom9110750.
    Publicado • 10.3390/biom9110750
  3. Abdulghani, Saba. "Tools to define and evaluate morphology mapping, a route to complex structures using direct digital manufacturing". AIP Conference Proceedings (2019): http://dx.doi.org/10.1063/1.5114229.
    10.1063/1.5114229
  4. Abdulghani, Saba. "Biofabrication for osteochondral tissue regeneration: bioink printability requirements". Journal of Materials Science: Materials in Medicine (2019): http://dx.doi.org/10.1007/s10856-019-6218-x.
    10.1007/s10856-019-6218-x
  5. Vidal, B.; Pinto, A.; Galvão, M.J.; Santos, A.R.; Rodrigues, A.; Cascão, R.; Abdulghani, S.; et al. "Bone histomorphometry revisited". Acta Reumatologica Portuguesa 37 4 (2012): 294-300. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876301488&partnerID=MN8TOARS.
  6. Caetano-Lopes, J.; Nery, A.M.; Canhão, H.; Duarte, J.; Cascão, R.; Rodrigues, A.; Perpétuo, I.P.; et al. "Chronic arthritis leads to disturbances in the bone collagen network". Arthritis Research and Therapy 12 1 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-77649302076&partnerID=MN8TOARS.
    10.1186/ar2908
  7. Ørskov, M.; Abdulghani, S.; McCarthy, I.; Søballe, K.; Flivik, G.. "Comparison of flanged and unflanged acetabular cup design: An experimental study using ceramic and cadaveric acetabuli". Acta Orthopaedica 81 5 (2010): 556-562. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957897086&partnerID=MN8TOARS.
    10.3109/17453674.2010.519167
  8. Caetano-Lopes, J.; Nery, A.M.; Henriques, R.; Canhão, H.; Duarte, J.; Amaral, P.M.; Vale, M.; et al. "Chronic arthritis directly induces quantitative and qualitative bone disturbances leading to compromised biomechanical properties". Clinical and Experimental Rheumatology 27 3 (2009): 475-482. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349116274&partnerID=MN8TOARS.
  9. Abdulghani, S.; Caetano-Lopes, J.; Canhão, H.; Fonseca, J.E.. "Biomechanical effects of inflammatory diseases on bone-rheumatoid arthritis as a paradigm". Autoimmunity Reviews 8 8 (2009): 668-671. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349276643&partnerID=MN8TOARS.
    10.1016/j.autrev.2009.02.021
  10. Abdulghani, S.; Wang, J.-S.; McCarthy, I.; Flivik, G.. "The influence of initial pressurization and cup introduction time on the depth of cement penetration in an acetabular model". Acta Orthopaedica 78 3 (2007): 333-339. http://www.scopus.com/inward/record.url?eid=2-s2.0-34347401193&partnerID=MN8TOARS.
    10.1080/17453670710013889
  11. Kjellson, F.; Abdulghani, S.; Tanner, K.E.; McCarthy, I.D.; Lidgren, L.. "Effect of iodixanol particle size on the mechanical properties of a PMMA based bone cement". Journal of Materials Science: Materials in Medicine 18 6 (2007): 1043-1051. http://www.scopus.com/inward/record.url?eid=2-s2.0-34248995287&partnerID=MN8TOARS.
    10.1007/s10856-006-0116-8
  12. Xu, H.; Abdulghani, S.; Behiri, J.; Sabokbar, A.. "Osteolytic potential of triphenyl bismuth as an alternative contrast medium in acrylic bone cement". Journal of Biomedical Materials Research - Part B Applied Biomaterials 75 1 (2005): 64-73. http://www.scopus.com/inward/record.url?eid=2-s2.0-25844459980&partnerID=MN8TOARS.
    10.1002/jbm.b.30277
  13. Abdulghani, S.; Nazhat, S.N.; Behiri, J.C.; Deb, S.. "Effect of triphenyl bismuth on glass transition temperature and residual monomer content of acrylic bone cements". Journal of Biomaterials Science, Polymer Edition 14 11 (2003): 1229-1242. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344035321&partnerID=MN8TOARS.
    10.1163/156856203322553455
  14. Deb, S.; Abdulghani, S.; Behiri, J.C.. "Radiopacity in bone cements using an organo-bismuth compound". Biomaterials 23 16 (2002): 3387-3393. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035989712&partnerID=MN8TOARS.
    10.1016/S0142-9612(02)00039-X
Livro
  1. Wang, J.-S.; Tanner, K.E.; Abdulghani, S.; Lidgren, L.. Indentation testing of a bone defect filled with two different injectable bone substitutes. 2005.
Poster em conferência
  1. Abdulghani, Saba. "Bone mineral density distribution in early osteoporotic bone". Trabalho apresentado em European calcified tissue society congress, 2013.
    10.1530/boneabs.1.PP328
Resumo em conferência
  1. Abdulghani, Saba. "UNDERSTANDING THE NANOSTRUCTURAL CHANGES IN OSTEOPOROTIC BONE USING SMALL ANGLE X-RAY SCATTERING IN A MOUSE MODEL". Trabalho apresentado em 8th Meeting of Portuguese Synchrotron Radiation Users, Porto, 2019.
    Aceite para publicação
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2021/06/28 The implementation of CHAIN BIOBANK at NOVA Medical School. . Oral presentation, 28-30 June 2021.
Portuguese Foundation for Science and Technology - FCT (Lisbon, Portugal)
2020/11/19 The implementation of CHAIN-BIOBANK at NOVA medical school 1st Comprehensive Health Research Centre Annual Summit
Comprehensive health research Centre, NOVA medical school, UNL (Portugal, Polónia)
2019/06/28 Understanding the nanostructural changes in osteoporotic bone using small angle X-ray scattering in an animal model of osteoporosis The 8th Meeting of Portuguese Synchrotron Radiation Users (ENURS 2019)
University of Porto (Porto, Portugal)
2018/10/12 Biomaterials and Biomechanics: applications in the World of Orthopaedics CFTC-IBEB Initiative: Soft Matter in Biomedicine
Faculty of Science, institute of biophysics and biomedical engineering (lisbon, Portugal)
2018/06/11 A framework of materials for 4d printing 19th World Congress on Materials Science and Engineering
(barcelona, Espanha)
2018/06/08 The use of time-resolved small-angle x-ray scattering techniques to evaluate the molecular organisation changes in 3d printed TPU 7th Meeting of Portuguese Users of Synchrotron Radiation, Lisbon 08 June 2018,
FCT-NOVA LISBOA, Lisbon-Portugal (Lisbon, Portugal)
2013/05/18 Structural and mechanical evaluation of the mineral and organic phases in osteoporotic bone using an animal model of osteoporosis European calcified tissue society congress
European calcified tissue society (Lisbon, Portugal)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2018/09/01 - 2019/09/06 The design and manufacture of a dynamic, multi-modal phantom of a life-size mouse using direct digital manufacturing techniques.
Coorientador
2010/12/01 - 2011/11/01 Structural and mechanical evaluation of osteoporotic bone using animal and human models
Coorientador
Biomedical engineering (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2005/04/01 - 2006/04/01 The influence of pore-interconnectivity in cancellous bone on cement infiltration and spreading
Coorientador
Biomedical Engineering (Mestrado)
Lunds Universitet Tekniska Högskola, Suécia

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2019/10/30 Master degree defense: Upregulation of Wnt regulators is associated with low bone mass in elderly Portuguese men and women
Arguente
DOMINIK KÖNIG GUERREIRO (Mestrado)
Universidade Nova de Lisboa Centro de Física e Investigação Tecnológica, Portugal
2018/11 NEW MARKERS, PREVALENCE AND BURDEN OF OSTEOPOROSIS AND FRAGILITY FRACTURES
Vogal
Ana Maria Rodriguese (Doutoramento)
Universidade de Lisboa, Portugal

Arbitragem científica em conferência

Nome da conferência Local da conferência
2021/06/25 - 2021/06/25 9th National Meeting of Portuguese Users of Synchrotron Radiation -ENURS Centre for Rapid and Sustainable Product Development, Polytechnic Institute of Leiria
2020/05/19 - 2020/05/24 World Biomaterials Conference University of Glasgo, Scotland

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2021/02/27 - Atual Frontiers in Materials Frontiers

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2020/09/01 - Atual Core methodologies of Research: Biobanks. Nova Medical School doctoral program Core methodologies of Research: Biobanks. (Doutoramento) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Distinções

Prémio

2021 Comprehensive Health Research Centre Research Award
Universidade Nova de Lisboa Comprehensive Health Research Centre, Portugal
2010 Saba Abdulghani
European Calcified Tissue Society, Reino Unido
2004 Saba Abdulghani
European Commission, Bélgica