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I have a PhD in Health Sciences and a master's degree in Biomedical Engineering with a specialization in Medical Informatics. During my masters’ dissertation at University of Minho, I worked in medical imaging and three-dimensional (3D) reconstruction, specifically in the 3D reconstruction of bone structures from planar radiography images. During this period, I did an oral presentation at the 6th International Symposium on Ambient Intelligence (Salamanca, Spain), which resulted in the publication of a conference paper entitled “3D Reconstruction of Bone Structures Based on Planar radiography”. My master’s degree work was continued through a 9 months’ internship at a startup (PeekMed) whose main goal is to develop a software to help physicians in pre-operative planning of orthopedic surgeries. With this, I developed my expertise in computer vision and image processing. After this internship, I moved to the neurosciences field and started my research career. First, I started working as a research technician in the project “Pharmacogenetics study of the answer to treatment in Attention-Deficit/Hyperactivity Disorder (ADHD) and in Obsessive Compulsive Disorder (OCD)” (an international collaboration between University of Minho, Portugal and Fundación Publica Galega de Medicina Xenómica, Santiago de Compostela, Spain). My main activity was the analysis of functional Magnetic Resonance Imaging (fMRI) data, including the preprocessing steps and statistical analysis. Also, alongside with this job I was also participating in other projects with researchers from the Life and Health Sciences Research Institute (ICVS, University of Minho, Portugal) by doing fMRI analysis. Then, I started my PhD project at ICVS, which was focused in finding MRI biomarkers of cognitive preservation and decline in healthy aging. I developed my skills in neurosciences, statistics, research methodologies and machine learning by attending post-graduate courses. With my PhD project, I started analyzing different types of MRI acquisitions, like diffusion weighted imaging and structural data, which gave me the expertise to analyze different kinds of MRI data. I also developed new analytical tools (involving data science and machine learning skills) which helped reveal new insights about brain's connectivity and which are published in international peer-reviewed journals (Human Brain Mapping, Scientific Reports, Journal of Neuroscience Research). During my PhD, I also collaborated in other neuroimaging projects from ICVS, which resulted in 11 publications, and I also contributed in teaching activities for the Integrated Masters in Biomedical Engineering and Medicine and in postgraduate courses for the PhD and Masters in Health Sciences. Furthermore, I also participated in pop-science activities. In November 2021, I successfully defended my PhD thesis, with the classification of Muito Bom. Currently, I am collaborating as a researcher with Centro Clínico Académico – Braga and ICVS and my current lines of research focus on the use of new neuroimaging tools to discover new brain biomarkers of cognitive decline that could help promote healthier cognitive ageing.
Identificação

Identificação pessoal

Nome completo
Ana Isabel de Araújo Coelho

Nomes de citação

  • Coelho, Ana

Identificadores de autor

Ciência ID
E612-E3B3-2758
ORCID iD
0000-0001-8489-5750

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2017/05/24 - 2021/11/24
Concluído
Doctorate Program in Health Sciences (Doutoramento)
Universidade do Minho Escola de Medicina, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
"The human brain connectome in aging: MRI biomarkers of congnitive preservation and decline" (TESE/DISSERTAÇÃO)
Muito Bom
2010/09 - 2015/12
Concluído
Integrated Masters in Biomedical Engineering (Mestrado)
Especialização em Medical Informatics
Universidade do Minho Escola de Engenharia, Portugal
"A 3D computer assisted Orthopedic Surgery Planning approach based on planar radiography" (TESE/DISSERTAÇÃO)
17
Percurso profissional

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2022/05/02 - Atual Data Scientist MediaProbe, Portugal
2016/11/28 - 2017/04/18 Research Technician Fundación Ramón Domínguez, Espanha
2015/09/01 - 2016/05/31 Software Developer PeekMed, Portugal
Projetos

Projeto

Designação Financiadores
2022/01/01 - Atual Influence of sex and gender on the stress response: going beyond the binary framework for improving personalized healthcare
PTDC/EMD-EMD/1140/2020
Bolseiro de Doutoramento
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2022/01/01 - Atual Social memory and its neural correlates in multiple sclerosis
EXPL/MEC-NEU/0888/2021
Bolseiro de Doutoramento
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Fundação para a Ciência e a Tecnologia
2022/01 - Atual Social memory and its neural correlates in multiple sclerosis
EXPL/MEC-NEU/0888/2021
Fundação para a Ciência e a Tecnologia
2022/01/01 - 2023/12/31 A influência do sexo e do género na resposta ao stress: ultrapassar o paradigma binário para melhorar os cuidados de saúde personalizados
EXPL/PSI-GER/1030/2021
Universidade do Minho, Portugal

Institut d'Investigació Biomèdica de Bellvitge, Espanha

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Coelho, Ana; Pedro S Moreira; Almeida, Pedro R.; Dias, Nuno. "LSTM-based network churn classification from EDA phasic data". 2023.
    10.1109/cai54212.2023.00115
  2. Coelho, A.; Ribeiro, J.P.; Campos, J.; Silva, S.; Alves, V.. "3D reconstruction of bone structures based on planar radiography". Trabalho apresentado em 6th International Symposium on Ambient Intelligence, Salamanca, 2015.
    Publicado • 10.1007/978-3-319-19695-4_14
Artigo em revista
  1. Torcato Meira; Ana Coelho; Seyda Onat; Luís Ruano; João José Cerqueira. "One-year regional brain volume changes as potential predictors of cognitive function in multiple sclerosis: a pilot study". Irish Journal of Medical Science (1971 -) (2023): https://doi.org/10.1007/s11845-023-03528-x.
    10.1007/s11845-023-03528-x
  2. Vieira, Rita; Reis, Joana; Portugal-Nunes, Carlos; Coelho, Ana; Magalhães, Ricardo; Ferreira, Sónia; Pedro S Moreira; et al. "Anticipatory cues in emotional processing shift the activation of a combined salience sensorimotor functional network in drug-naïve depressed patients". Journal of Affective Disorders 320 (2023): 509-516. http://dx.doi.org/10.1016/j.jad.2022.09.165.
    10.1016/j.jad.2022.09.165
  3. Ana Coelho; Nuno Sousa. "Magnetic resonance elastography of the ageing brain in normal and demented populations: A systematic review". Human Brain Mapping (2022): https://doi.org/10.1002/hbm.25891.
    10.1002/hbm.25891
  4. Ana Coelho; Ricardo Magalhães; Pedro S. Moreira; Liliana Amorim; Carlos Portugal-Nunes; Teresa Castanho; Nadine Correia Santos; Nuno Sousa; Henrique M. Fernandes. "A novel method for estimating connectivity-based parcellation of the human brain from diffusion MRI: Application to an aging cohort". Human Brain Mapping (2022): https://doi.org/10.1002/hbm.25773.
    10.1002/hbm.25773
  5. Reis, Joana Vanessa; Vieira, Rita; Portugal-Nunes, Carlos; Coelho, Ana; Magalhães, Ricardo; Moreira, Pedro; Ferreira, Sónia; et al. "Suicidal Ideation Is Associated With Reduced Functional Connectivity and White Matter Integrity in Drug-Naïve Patients With Major Depression". Frontiers in Psychiatry 13 (2022): http://dx.doi.org/10.3389/fpsyt.2022.838111.
    10.3389/fpsyt.2022.838111
  6. Caetano, Ines; Amorim, Liliana; Castanho, Teresa Costa; Coelho, Ana; Ferreira, Sonia; Portugal-Nunes, Carlos; Soares, Jose Miguel; et al. "Association of amygdala size with stress perception: Findings of a transversal study across the lifespan". European Journal of Neuroscience (2022): https://publons.com/wos-op/publon/51844888/.
    10.1111/EJN.15809
  7. Caetano, Ines; Ferreira, Sonia; Coelho, Ana; Amorim, Liliana; Castanho, Teresa Costa; Portugal-Nunes, Carlos; Soares, Jose Miguel; et al. "Perceived stress modulates the activity between the amygdala and the cortex". Molecular Psychiatry (2022): https://publons.com/wos-op/publon/54653536/.
    10.1038/S41380-022-01780-8
  8. Reis, Joana Vanessa; Vieira, Rita; Portugal-Nunes, Carlos; Coelho, Ana; Magalhaes, Ricardo; Moreira, Pedro; Ferreira, Sonia; et al. "Suicidal Ideation Is Associated With Reduced Functional Connectivity and White Matter Integrity in Drug-Naive Patients With Major Depression". Frontiers in Psychiatry (2022): https://publons.com/wos-op/publon/51887738/.
    10.3389/FPSYT.2022.838111
  9. Coelho, Ana; Fernandes, Henrique M.; Magalhães, Ricardo; Moreira, Pedro S.; Marques, Paulo; Soares, José M.; Amorim, Liliana; et al. "Signatures of white-matter microstructure degradation during aging and its association with cognitive status". Scientific Reports 11 1 (2021): http://dx.doi.org/10.1038/s41598-021-83983-7.
    10.1038/s41598-021-83983-7
  10. Portugal-Nunes, Carlos; Reis, Joana; Coelho, Ana; Moreira, Pedro S.; Castanho, Teresa C.; Magalhães, Ricardo; Marques, Paulo; et al. "The Association of Metabolic Dysfunction and Mood Across Lifespan Interacts With the Default Mode Network Functional Connectivity". Frontiers in Aging Neuroscience 13 (2021): http://dx.doi.org/10.3389/fnagi.2021.618623.
    10.3389/fnagi.2021.618623
  11. Vieira, Rita; Coelho, Ana; Reis, Joana; Portugal-Nunes, Carlos; Magalhães, Ricardo; Ferreira, Sónia; Moreira, Pedro S.; Sousa, Nuno; Bessa, João M.. "White Matter Microstructure Alterations Associated With Paroxetine Treatment Response in Major Depression". Frontiers in Behavioral Neuroscience 15 (2021): http://dx.doi.org/10.3389/fnbeh.2021.693109.
    10.3389/fnbeh.2021.693109
  12. Ferreira, Sónia; Moreira, Pedro S.; Magalhães, Ricardo; Coelho, Ana; Marques, Paulo; Portugal-Nunes, Carlos; Silva, Catarina; Sousa, Nuno; Morgado, Pedro. "Frontoparietal hyperconnectivity during cognitive regulation in obsessive-compulsive disorder followed by reward valuation inflexibility". Journal of Psychiatric Research 137 (2021): 657-666. http://dx.doi.org/10.1016/j.jpsychires.2020.11.008.
    10.1016/j.jpsychires.2020.11.008
  13. Caetano, Inês; Amorim, Liliana; Soares, José M.; Ferreira, Sónia; Coelho, Ana; Reis, Joana; Santos, Nadine C.; et al. "Amygdala size varies with stress perception". Neurobiology of Stress 14 (2021): 100334-100334. http://dx.doi.org/10.1016/j.ynstr.2021.100334.
    10.1016/j.ynstr.2021.100334
  14. Magalhães, Ricardo; Picó-Pérez, Maria; Esteves, Madalena; Vieira, Rita; Castanho, Teresa C.; Amorim, Liliana; Sousa, Mafalda; et al. "Habitual coffee drinkers display a distinct pattern of brain functional connectivity". Molecular Psychiatry (2021): http://dx.doi.org/10.1038/s41380-021-01075-4.
    10.1038/s41380-021-01075-4
  15. Coelho, Ana; Henrique M. Fernandes; Ricardo Magalhães; Pedro S. Moreira; Paulo Marques; José M. Soares; Liliana Amorim; et al. "Reorganization of brain structural networks in aging: A longitudinal study". Journal of Neuroscience Research (2021): https://doi.org/10.1002/jnr.24795.
    10.1002/jnr.24795
  16. Rodrigues, Belina; Coelho, Ana; Portugal-Nunes, Carlos; Magalhães, Ricardo; Moreira, Pedro; Castanho, Costa Teresa; Amorim, Liliana; et al. "Higher Adherence to the Mediterranean Diet Is Associated With Preserved White Matter Integrity and Altered Structural Connectivity.". Frontiers in neuroscience (2020): https://europepmc.org/articles/PMC7434945.
    10.3389/fnins.2020.00786
  17. Amorim, Liliana; Magalhães, R.; Coelho, Ana; Moreira, Pedro Silva; Portugal-Nunes, Carlos; Castanho, Teresa Costa; Marques, P.; Sousa, N.; Santos, N.C.. "Linking sleep quality to brain connectivity: a multimodal MRI approach in normative ageing". Sleep Medicine 64 (2019): S14-S15. http://dx.doi.org/10.1016/j.sleep.2019.11.043.
    10.1016/j.sleep.2019.11.043
  18. Moreira PS; Macoveanu J; Marques P; Coelho A; Magalhães R; Siebner HR; Soares JM; Sousa N; Morgado P. "Altered response to risky decisions and reward in patients with obsessive–compulsive disorder". Journal of psychiatry & neuroscience : JPN (2019): http://europepmc.org/abstract/med/31509362.
    10.1503/jpn.180226
  19. Ferreira S; Veiga C; Moreira P; Magalhães R; Coelho A; Marques P; Portugal-Nunes C; Sousa N; Morgado P. "Reduced Hedonic Valuation of Rewards and Unaffected Cognitive Regulation in Chronic Stress.". Frontiers in neuroscience (2019): http://europepmc.org/abstract/med/31354423.
    10.3389/fnins.2019.00724
  20. Madalena Esteves; Pedro S. Moreira; Paulo Marques; Teresa C. Castanho; Ricardo Magalhães; Liliana Amorim; Carlos Portugal-Nunes; et al. "Asymmetrical subcortical plasticity entails cognitive progression in older individuals". Aging Cell 18 1 (2019): e12857-e12857. https://doi.org/10.1111/acel.12857.
    10.1111/acel.12857
  21. Liliana Amorim; Ricardo Magalhães; Ana Coelho; Pedro Silva Moreira; Carlos Portugal-Nunes; Teresa Costa Castanho; Paulo Marques; Nuno Sousa; Nadine Correia Santos. "Poor Sleep Quality Associates With Decreased Functional and Structural Brain Connectivity in Normative Aging: A MRI Multimodal Approach". Frontiers in Aging Neuroscience 10 (2018): https://doi.org/10.3389%2Ffnagi.2018.00375.
    10.3389/fnagi.2018.00375
  22. Coelho, A.; Marques, P.; Magalhães, R.; Sousa, N.; Neves, J.; Alves, V.. "A knowledge representation and reasoning system for multimodal neuroimaging studies". Inteligencia Artificial 20 59 (2017): 42-52. http://www.scopus.com/inward/record.url?eid=2-s2.0-85015990299&partnerID=MN8TOARS.
    10.4114/intartif.vol20iss59pp42-52
Poster em conferência
  1. Esteves, Madalena; Magalhães, Ricardo; Picó-Perez, Maria; Vieira, Rita; Castanho, Costa Teresa; Amorim, Liliana; Sousa, Mafalda; et al. "Your brain on coffee: psychological and resting-state effects of coffee consumption.". Trabalho apresentado em 12th FENS Forum of Neuroscience, Glasgow UK, 2020.
  2. Ferreira, Sónia; Moreira, Pedro; Magalhaes, Ricardo; Coelho, Ana; Marques, Paulo; Portugal-Nunes, Carlos; Sousa, Nuno; Morgado, Pedro. "Decreased cognitive flexibility impairs decision-making in obsessive-compulsive disorder ¿ a functional magnetic resonance imaging study". Trabalho apresentado em ECNP congress, 2019.
Pré-impressão
  1. Magalhães, Ricardo; Gonçalves, Nuno; Sousa, Rui; Coelho, Ana; Soares-Cunha, Carina; Moreira, Pedro; Marques, Paulo; et al. "Impact of prenatal synthetic glucocorticoid exposure on the adolescent brain". 2023. http://dx.doi.org/10.1101/2023.04.14.536872.
    10.1101/2023.04.14.536872
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2015/06 3D Reconstruction of Bone Structures Based on Planar radiography 6th International Symposium on Ambient Intelligence
Bioinformatic, Intelligent System and Educational Technology Research Group of the University of Salamanca (Salamanca, Espanha)

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2021/06 - 2021/06 Online course
Oficina (workshop)
IDEA Sequence Programming
Siemens Healthcare GmbH, Alemanha
2021/06 - 2021/06 Online course
Oficina (workshop)
A Arte de Comunicar em Público
Universidade do Minho, Portugal
2021/05 - 2021/05 Online course
Oficina (workshop)
Introduction to Structural Equation Modeling
CenterStat by Curran-Bauer Analytics, Estados Unidos
2021/04 - 2021/04 Online course
Oficina (workshop)
Improving Deep Neural Networks: Hyperparameter Tuning, Regularization and Optimization
Coursera, Estados Unidos
2021/03 - 2021/03 Online course
Oficina (workshop)
Neural Networks and Deep Learning
Coursera, Estados Unidos
2020/12 - 2020/12 Poster presentation: Coelho, A., Fernandes, H. M., Magalhães, R., Moreira, P. S., Marques, P., Soares, J. M., Amorim, L., Portugal-Nunes, C., Castanho, T., Santos, N. C., Sousa, N. "The human brain connectome in aging: MRI biomarkers of cognitive preservation and decline".
Encontro
NeRD Annual Retreat, Online
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2020/10 - 2020/10 Course
Oficina (workshop)
Computational Data Analysis
Universidade do Minho Escola de Medicina, Portugal
2020/02 - 2020/02 Course
Oficina (workshop)
Being a Bio-Entrepreneur
Universidade do Minho Escola de Medicina, Portugal
2019/11 - 2019/11 Poster presentation: Coelho, A., Fernandes, H. M., Magalhães, R., Moreira, P. S., Amorim, L., Portugal-Nunes, C., Castanho, T., Santos, N. C.,Sousa, N. "A novel method for estimating connectivity-based parcellation of the human brain from diffusion MRI".
Encontro
NeRD Annual Retreat, Guimarães, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/07 - 2019/07 Course
Oficina (workshop)
9th Lisbon Machine Learning School
Instituto Superior Técnico Departamento de Engenharia e Gestão, Portugal

Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento em Lisboa, Portugal

Instituto de Telecomunicações, Portugal
2019/06 - 2019/06 Poster presentation: Coelho, A., Fernandes, H. M., Magalhães, R., Moreira, P. S., Sousa, N. "A novel method for estimating connectivity-based parcellation of the human brain from diffusion MRI".
Congresso
25th OHBM Annual Meeting, Rome, Italy
Organization for Human Brain Mapping (OHBM), Estados Unidos
2019/04 - 2019/04 Participation in the contest for science communication "Dance your PhD" from the Life and Health Sciences Research Institute (ICVS) Open Day with the video (awarded as best video) "Neurofeedback Awakens: The Attack of the Obsessive Mind" (https://photos.app.goo.gl/hNRygfR6cpRKcCUh8).
Encontro
ICVS Open Day
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/04 - 2019/04 Course
Oficina (workshop)
QuantaLab Workshop in Quantum Computation
Universidade do Minho Escola de Ciências, Portugal
2019/01 - 2019/01 Course
Oficina (workshop)
Advanced Methods for Reproducible Science Workshop
University of Bristol, Reino Unido
2018/12 - 2018/12 Poster presentation: Coelho, A., Magalhães, R., Moreira, P. S., Amorim, L., Sousa, N. "Micro-structural white matter differences in healthy aging: a longitudinal study".
Encontro
NeRD Annual Retreat, Guimarães, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/01 - 2018/01 Course
Oficina (workshop)
Biostatistics in Health Sciences
Universidade do Minho Escola de Medicina, Portugal
2017/11 - 2017/11 Poster presentation: Coelho, A., Marques, P., Magalhães, R., Moreira, P. S., Sousa, N. "Changes in structural connectome during healthy aging: a longitudinal study"
Encontro
NeRD Annual Retreat, Guimarães, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/11 - 2017/11 Course
Oficina (workshop)
Research Methodologies
Universidade do Minho Escola de Medicina, Portugal
2017/09 - 2017/09 Course
Oficina (workshop)
Fundamentals in Neuroscience
Universidade do Minho Escola de Medicina, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2021 - Atual "Neuroimaging Lab" part of the Imaging curricular unit Integrated Masters Degree in Biomedical Engineering (Mestrado integrado) Universidade do Minho Escola de Engenharia, Portugal
2020 - Atual DCBM course (Da clínica à biologia molecular) Integrated Masters Degree in Medicine (Mestrado integrado) Universidade do Minho Escola de Medicina, Portugal
2019 - Atual "Neuroimaging Lab" part of the Fundamentals in Neuroscience course PhD/Masters degree in Health Sciences Universidade do Minho Escola de Medicina, Portugal
Distinções

Prémio

2019 Dance your PhD Award
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal