Artigo em revista |
- Ramos, Helena; Reis-Mendes, Ana; Silva, Marta; Ribeiro, Mafalda; Araújo, Ana Margarida; Borges, Cristiane; Viegas, Olga; et
al. "Exposure Scenarios for Estimating Contaminant Levels in Healthy Sustainable Dietary Models: Omnivorous vs. Vegetarian".
Foods 13 22 (2024): 3659. http://dx.doi.org/10.3390/foods13223659.
Publicado • 10.3390/foods13223659
- Araújo, Ana Margarida; Marques, Sandra; Guedes de Pinho, Paula; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. Autor correspondente:
Araújo, Ana Margarida. "Identification of key neuronal mechanisms triggered by dimethyl fumarate in SH-SY5Y human neuroblastoma
cells through a metabolomic approach". Archives of Toxicology 98 (2024): 1151-1161.
Publicado • 10.1007/s00204-024-03683-9
- Dias-Carvalho, Ana; Margarida-Araújo, Ana; Reis-Mendes, Ana; Sequeira, Catarina Oliveira; Pereira, Sofia Azeredo; Guedes de
Pinho, Paula; Carvalho, Félix; et al. "A Clinically Relevant Dosage of Mitoxantrone Disrupts the Glutathione and Lipid Metabolic
Pathways of the CD-1 Mice Brain: A Metabolomics Study". International Journal of Molecular Sciences 24 17 (2023): 13126.
http://dx.doi.org/10.3390/ijms241713126.
Publicado • 10.3390/ijms241713126
- Araújo, Ana Margarida; Ringeard, Henri; Nunes, Bruno. Autor correspondente: Araújo, Ana Margarida. "Do microplastics influence
the long-term effects of ciprofloxacin on the polychaete Hediste diversicolor? An integrated behavioral and biochemical approach".
Environmental Toxicology and Pharmacology 99 (2023): https://doi.org/10.1016/j.etap.2023.104088.
Publicado • 10.1016/j.etap.2023.104088
- Martins, Zita E.; Ramos, Helena; Araújo, Ana Margarida; Silva, Marta; Ribeiro, Mafalda; Melo, Armindo; Mansilha, Catarina;
et al. "From data to insight: Exploring contaminants in different food groups with literature mining and machine learning
techniques". Current Research in Food Science 7 (2023): 100557. http://dx.doi.org/10.1016/j.crfs.2023.100557.
Publicado • 10.1016/j.crfs.2023.100557
- Dionísio, Flávio; Araújo, Ana Margarida; Duarte-Araújo, Margarida; Bastos, Maria de Lourdes; Guedes de Pinho, Paula; Carvalho,
Félix; Costa, Vera Marisa. "Cardiotoxicity of cyclophosphamide’s metabolites: an in vitro metabolomics approach in AC16 human
cardiomyocytes". Archives of Toxicology 96 (2021): 653-671. https://link.springer.com/article/10.1007/s00204-021-03204-y.
Publicado • 10.1007/s00204-021-03204-y
- Araújo, Ana Margarida; Carvalho, Félix; Guedes de Pinho P.; Carvalho, Márcia. Autor correspondente: Araújo, Ana Margarida.
"Toxicometabolomics: Small Molecules to Answer Big Toxicological Questions". Metabolites (2021): https://www.mdpi.com/2218-1989/11/10/692.
Publicado • 10.3390/metabo11100692
- Araújo, Ana Margarida; Carvalho, Márcia; Costa, Vera Marisa; Duarte, José Alberto; Dinis-Oliveira, Ricardo Jorge; Bastos,
Maria de Lourdes; Guedes de Pinho, Paula; Carvalho, Félix. "In vivo toxicometabolomics reveals multi-organ and urine metabolic
changes in mice upon acute exposure to human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV)". Archives of Toxicology
95 2 (2020): 509-527. http://dx.doi.org/10.1007/s00204-020-02949-2.
Publicado • 10.1007/s00204-020-02949-2
- Vaz, I.; Carvalho, T.; Valente, M.J.; Castro, A.; Araújo, A.M.; Bastos, M.L.; Carvalho, M.. "The interplay between autophagy
and apoptosis mediates toxicity triggered by synthetic cathinones in human kidney cells". Toxicology Letters 331 (2020):
42-52. http://dx.doi.org/10.1016/j.toxlet.2020.05.025.
Publicado • 10.1016/j.toxlet.2020.05.025
- Araújo, Ana Margarida; Bastos, Maria de Lourdes; Carvalho, Félix; Guedes de Pinho, Paula; Carvalho, Márcia. "Effect of temperature
on 3,4-Methylenedioxypyrovalerone (MDPV)-induced metabolome disruption in primary mouse hepatic cells". Toxicology
441 (2020): 152503. http://dx.doi.org/10.1016/j.tox.2020.152503.
Publicado • 10.1016/j.tox.2020.152503
- Enea, Maria; Pereira, Eulália; Peixoto de Almeida, Miguel; Araújo, Ana Margarida; Bastos, Maria de Lourdes; Carmo, Helena.
"Gold nanoparticles induce oxidative stress and apoptosis in human kidney cells". Nanomaterials 10 5 (2020): 995. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279525/.
Publicado • 10.3390/nano10050995
- Amaro, Filipa; Pinto, Joana; Rocha, Sílvia; Araújo, Ana Margarida; Miranda-Gonçalves, Vera; Jerónimo, Carmen; Henrique, Rui;
et al. "Volatilomics reveals potential biomarkers for identification of renal cell carcinoma: an in vitro approach". Metabolites
(2020): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281256/.
Publicado • 10.3390/metabo10050174
- Araújo, Ana Margarida; Enea, Maria; Fernandes, Eduarda; Carvalho, Félix; de Lourdes Bastos, Maria; Carvalho, Márcia; Guedes
de Pinho, Paula. "3,4-Methylenedioxymethamphetamine Hepatotoxicity under the Heat Stress Condition: Novel Insights from in
Vitro Metabolomic Studies". Journal of Proteome Research 19 3 (2020): 1222-1234. http://dx.doi.org/10.1021/acs.jproteome.9b00741.
Publicado • 10.1021/acs.jproteome.9b00741
- Enea M; Araújo AM; Almeida MP; Soares ME; Gonçalves-Monteiro S; Pinho PG; Pereira E; Bastos ML; Carmo H. "A Metabolomic Approach
for the In Vivo Study of Gold Nanospheres and Nanostars after a Single-Dose Intravenous Administration to Wistar Rats.". Nanomaterials
(2019): http://europepmc.org/abstract/med/31726761.
Publicado • 10.3390/nano9111606
- Ana Margarida Araújo; Maria Enea; Félix Carvalho; Bastos ML; Carvalho M; Guedes de Pinho P.. Autor correspondente: Ana Margarida
Araújo. "Hepatic Metabolic Derangements Triggered by Hyperthermia: An In Vitro Metabolomic Study". Metabolites (2019):
https://www.mdpi.com/2218-1989/9/10/228.
Publicado • 10.3390/metabo9100228
- Araújo AM; Carvalho M; Bastos ML; Carvalho F; de Pinho PG. Autor correspondente: Araújo AM. "Metabolic signature of methylone
in primary mouse hepatocytes, at subtoxic concentrations.". Archives of toxicology (2019): http://europepmc.org/abstract/med/31494693.
Publicado • 10.1007/s00204-019-02566-8
- Silva JP; Araújo AM; Guedes de Pinho P; Carmo H; Carvalho F. "Synthetic cannabinoids JWH-122 and THJ-2201 disrupt endocannabinoid-regulated
mitochondrial function and activate apoptotic pathways as a primary mechanism of in vitro nephrotoxicity at in vivo relevant
concentrations.". Toxicological sciences : an official journal of the Society of Toxicology (2019): http://europepmc.org/abstract/med/30796436.
Publicado • 10.1093/toxsci/kfz050
- Daniela Rodrigues; Joana Pinto; Ana Margarida Araújo; Carmen Jeronimo; Rui Henrique; Maria de Lourdes Bastos; Guedes de Pinho
P.; Carvalho M. "GC-MS Metabolomics Reveals Distinct Profiles of Low- and High-Grade Bladder Cancer Cultured Cells". Metabolites
(2019): http://www.mdpi.com/2218-1989/9/1/18.
Publicado • 10.3390/metabo9010018
- Rocha, S.; Araújo, A.M.; Almeida, A.; de Pinho, P.G.; Fernandes, E.. "Development and validation of a gc-ms/ms method for
cis-and trans-resveratrol determination: Application to portuguese wines". Food Analytical Methods 12 7 (2019): 1536-1544.
http://www.scopus.com/inward/record.url?eid=2-s2.0-85071185676&partnerID=MN8TOARS.
Publicado • 10.1007/s12161-019-01482-y
- Silva B; Pereira JA; Cravo S; Araújo AM; Fernandes C; Pinto MMM; de Pinho PG; Remião F. "Multi-milligram resolution and determination
of absolute configuration of pentedrone and methylone enantiomers.". Journal of chromatography. B, Analytical technologies
in the biomedical and life sciences (2018): http://europepmc.org/abstract/med/30336346.
Publicado • 10.1016/j.jchromb.2018.10.002
- Araújo AM; Bastos ML; Fernandes E; Carvalho F; Carvalho M; Guedes de Pinho P. Autor correspondente: Araújo AM. "GC-MS metabolomics
reveals disturbed metabolic pathways in primary mouse hepatocytes exposed to subtoxic levels of 3,4-methylenedioxymethamphetamine
(MDMA).". Archives of toxicology (2018): http://europepmc.org/abstract/med/30255327.
Publicado • 10.1007/s00204-018-2314-9
- Moreira N; Araújo AM; Rogerson F; Vasconcelos I; Freitas V; Pinho PG. "Development and optimization of a HS-SPME-GC-MS methodology
to quantify volatile carbonyl compounds in Port wines.". Food chemistry (2018): http://europepmc.org/abstract/med/30174081.
Publicado • 10.1016/j.foodchem.2018.07.093
- Araújo AM; Moreira N; Lima AR; de Lourdes Bastos M; Carvalho F; Carvalho M; de Pinho PG. Autor correspondente: Araújo AM.
"Analysis of extracellular metabolome by HS-SPME/GC-MS: optimization and application in a pilot study to evaluate galactosamine-induced
hepatotoxicity.". Toxicology letters (2018): http://europepmc.org/abstract/med/29852275.
Publicado • 10.1016/j.toxlet.2018.05.028
- Lima AR; Araújo AM; Pinto J; Jerónimo C; Henrique R; Bastos ML; Carvalho M; Guedes de Pinho P. "Discrimination between the
human prostate normal and cancer cell exometabolome by GC-MS.". Scientific reports (2018): http://europepmc.org/abstract/med/29615722.
Publicado • 10.1038/s41598-018-23847-9
- Lima, Ana Rita; Araújo, Ana; Pinto, Joana; Jerónimo, Carmen; Henrique, Rui; Bastos, Maria de Lourdes; Carvalho, Márcia; Guedes
de Pinho, Paula. "GC-MS-Based Endometabolome Analysis Differentiates Prostate Cancer from Normal Prostate Cells". Metabolites
8 1 (2018): http://www.mdpi.com/2218-1989/8/1/23.
Publicado • 10.3390/metabo8010023
- Rodrigues, D.; Pinto, J.; Araújo, A.M.; Monteiro-Reis, S.; Jerónimo, C.; Henrique, R.; de Lourdes Bastos, M.; de Pinho, P.G.;
Carvalho, M.. "Volatile metabolomic signature of bladder cancer cell lines based on gas chromatography–mass spectrometry".
Metabolomics 14 5 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85045689037&partnerID=MN8TOARS.
Publicado • 10.1007/s11306-018-1361-9
- Araújo AM; Carvalho M; Carvalho F; Bastos ML; Guedes de Pinho P. Autor correspondente: Araújo AM. "Metabolomic approaches
in the discovery of potential urinary biomarkers of drug-induced liver injury (DILI).". Critical Reviews in Toxicology
47 8 (2017): 633-649. http://europepmc.org/abstract/med/28436314.
Publicado • 10.1080/10408444.2017.1309638
- Machado, F.; Dias, M.C.; Pinho, P.G.D.; Araújo, A.M.; Pinto, D.; Silva, A.; Correia, C.; Moutinho-Pereira, J.; Santos, C..
"Photosynthetic performance and volatile organic compounds profile in Eucalyptus globulus after UVB radiation". Environmental
and Experimental Botany 140 (2017): 141-149. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021109795&partnerID=MN8TOARS.
Publicado • 10.1016/j.envexpbot.2017.05.008
- Valente MJ; Araújo AM; Bastos Mde L; Fernandes E; Carvalho F; Guedes de Pinho P; Carvalho M. "Editor's Highlight: Characterization
of Hepatotoxicity Mechanisms Triggered by Designer Cathinone Drugs (ß-Keto Amphetamines).". Toxicological Sciences
(2016): http://europepmc.org/abstract/med/27255387.
Publicado • 10.1093/toxsci/kfw105
- Valente MJ; Araújo AM; Silva R; Bastos Mde L; Carvalho F; Guedes de Pinho P; Carvalho M. "3,4-Methylenedioxypyrovalerone (MDPV):
in vitro mechanisms of hepatotoxicity under normothermic and hyperthermic conditions.". Archives of Toxicology (2016):
http://europepmc.org/abstract/med/26676947.
Publicado • 10.1007/s00204-015-1653-z
- Calejo I; Moreira N; Araújo AM; Carvalho M; Bastos Mde L; de Pinho PG. "Optimisation and validation of a HS-SPME-GC-IT/MS
method for analysis of carbonyl volatile compounds as biomarkers in human urine: Application in a pilot study to discriminate
individuals with smoking habits.". Talanta (2016): http://europepmc.org/abstract/med/26653476.
Publicado • 10.1016/j.talanta.2015.09.070
- Oliveira, Ana Sofia; Fraga, Sónia; Carvalho, Félix; Araújo, Ana Margarida; Costa Pereira, Cristiana; Teixeira, João Paulo;
Bastos, Maria de Lourdes; Guedes de Pinho, Paula. "Chemical characterization and in vitro cyto- and genotoxicity of "legal
high" products containing Kratom (Mitragyna speciosa)". Forensic Toxicology 34 (2016): 213-226. https://link.springer.com/article/10.1007/s11419-015-0305-6.
Publicado • 10.1007/s11419-015-0305-6
- Araújo AM; Carvalho F; Bastos ML; Guedes de Pinho P; Carvalho M. Autor correspondente: Araújo AM. "The hallucinogenic world
of tryptamines: an updated review.". Archives of Toxicology (2015): http://europepmc.org/abstract/med/25877327.
Publicado • 10.1007/s00204-015-1513-x
- Araújo AM; Valente MJ; Carvalho M; Dias da Silva D; Gaspar H; Carvalho F; de Lourdes Bastos M; Guedes de Pinho P. Autor correspondente:
Araújo AM. "Raising awareness of new psychoactive substances: chemical analysis and in vitro toxicity screening of 'legal
high' packages containing synthetic cathinones.". Archives of Toxicology (2014): http://europepmc.org/abstract/med/24903018.
Publicado • 10.1007/s00204-014-1278-7
|
Edição de número de revista |
- Araújo, Ana Margarida. "Advanced metabolic profiling via GC-MS and LC-MS". Metabolites (2024): https://www.mdpi.com/journal/metabolites/special_issues/19CKT2IQ61.
Editor convidado
- Araújo, Ana Margarida; Dimosthenis Andreas Sarigiannis. "Metabolomics: a sensitive approach to unravel the exposome fingerprint".
Frontiers in Toxicology (2023): https://www.frontiersin.org/research-topics/45210/metabolomics-a-sensitive-approach-to-unravel-the-exposome-fingerprint.
Editor convidado
- Araújo, Ana Margarida. "Toxicity Effects of Environmental Pollutants Based on Metabolomics". Toxics (2023): https://www.mdpi.com/journal/toxics/special_issues/toxicity_pollutant_metabolomic.
Editor convidado
- Araújo, Ana Margarida; Franchitto, Nicolas. "Methods and Protocols in Clinical Toxicology: 2023". Frontiers in Toxicology
(2023): https://www.frontiersin.org/research-topics/51847/methods-and-protocols-in-clinical-toxicology-2023.
Editor convidado
- Araújo, Ana Margarida; Márcia Cláudia Dias de Carvalho. "Toxicometabolomics". Metabolites (2022): https://www.mdpi.com/journal/metabolites/special_issues/Toxicometabolomics.
Editor convidado
|
Poster em conferência |
- Sousa, D.; Rocha, V.; Moreira, M.; Amaro, F.; Araújo, A. M.; Carvalho, M.. "Avaliação do potencial anticancerigeno do canabidiol
em células do carcinoma renal humano". Trabalho apresentado em Congresso Nacional dos Farmacêuticos, 2024.
- Araújo, Ana Margarida; Ramos, Helena; Ribeiro, Mafalda; Martins, Zita; Marin-Saez, Jesus; Lopez-Ruiz, Rosalia; Faria, Miguel;
Ferreira, Isabel M.P.L.V.O.. "Examining the impact of a realistic mixture of dietary contaminants on the intestinal barrier
and compounds absorption". Trabalho apresentado em 58th Congress of the European Societies of Toxicology (EUROTOX 2014),
2024.
- Dias-Carvalho, A.; Araújo, A. M.; Reis-Mendes, A.; Sequeira, C. Oliveira; Pereira, S. Azeredo; Guedes de Pinho, P.; Carvalho,
F.; et al. "Mitoxantrone disrupts brain glutathione defense and the metabolic pathways in CD-1 mice". Trabalho apresentado
em 58th Congress of the European Societies of Toxicology (EUROTOX 2014), 2024.
- Araújo, Ana Margarida; RAMOS, HELENA; Ribeiro, Mafalda; Martins, Zita E.; Faria, Miguel Angelo; Ferreira, Isabel M. P. L.
V. O.. "Unveiling a hidden threat: understanding how dietary contaminants shape intestinal barrier health through an in vitro
triple culture model". Trabalho apresentado em 8th International Conference on Food Digestion, 2024.
- Dias-Carvalho, Ana; Araújo, Ana Margarida; Reis-Mendes, A.; Sequeira, CO; Pereira, AS; Guedes de Pinho, Paula; Carvalho, Félix;
et al. "Chemobrain: exploring the impacto f a clinically relevant dose of mitoxantrone in the metabolic profile of CD-1 mice
brain". Trabalho apresentado em EMBO Young Scientists’ Forum (Lisbon), 2023.
- Valente, Maria João; Araújo, Ana Margarida; Carvalho, Félix; Carvalho, Márcia. "Toxicity of amphetamine-type drugs in rat
cardiomyocyte cells involves oxidative stress and the formation of acidic vesicular organelles". Trabalho apresentado em II
TOXRUN International Congress 2023 - No Boundaries for Toxicology: One Health, One Society, One Planet, 2023.
- Sousa, Débora; Amaro, Filipa; Araújo, Ana Margarida; Carvalho, Márcia. "Impact of Cannabidiol on Viability of Normal and Tumorigenic
Human Kidney Cells: are the effects serum-dependent?". Trabalho apresentado em II TOXRUN International Congress 2023 -
No Boundaries for Toxicology: One Health, One Society, One Planet, 2023.
- Martins, Zita E.; Silva, Marta; Ribeiro, Mafalda; Ramos, Helena; Araújo, Ana Margarida; Melo, Armindo; Teixeira, Carla; et
al. "The distribution of contaminants in foods according to the scientific literature mining and machine learning". Trabalho
apresentado em Dare2Change – Innovation-driven Agrifood Business, 2023.
- Araújo, Ana Margarida; Marques, Sandra; Carmo, Helena; Guedes de Pinho, Paula; Carvalho, Félix; Silva, João Pedro. "Application
of a GC-MS metabolomics approach to reveal how sub-toxic concentrations of ciprofloxacin affect the brain". Trabalho apresentado
em 12º National Meeting of Chromatography (12ENC), 2022.
- Bárbara Sousa; Araújo, Ana Margarida; Inês Guimarães; Fátima Rato; Márcia Cláudia Dias de Carvalho. "Impact of COVID-19 pandemic
on the patterns of toxic exposure: a retrospective analysis of Portuguese poison centre database". Trabalho apresentado em
APCF-TOXRUN International Congress 2022, 2022.
- Araújo, Ana Margarida; Sandra Marques; Carmo, Helena; Maria Paula do Amaral Alegria Guedes de Pinho; Carvalho, Félix; João
Pedro Silva. "Can fluoroquinolone affect the brain? - A GC-MS metabolomics approach reveals early neurotoxicity events triggered
by ciprofloxacin"". Trabalho apresentado em 61st Annual meeting and ToxExpo (SOT2022), 2022.
- Amaro, Filipa; Pinto, Joana; Silvia Rocha; Araújo, Ana Margarida; Miranda-Gonçalves, Vera; Jerónimo, Carmen; Henrique, Rui;
et al. "In vitro volatile exometabolome signature of clear cell renal cell carcinoma". Trabalho apresentado em EUROTOX,
2021.
- Araújo, Ana Margarida; Márcia Cláudia Dias de Carvalho; Costa, Vera Marisa; Duarte, José Alberto; Dinis-Oliveira, Ricardo
Jorge; Bastos, Maria de Lourdes; Maria Paula do Amaral Alegria Guedes de Pinho; Carvalho, Félix. "Early pathways of toxicity
triggered by 3,4-methylenedioxypyrovalerone (MDPV) unveiled by in vivo toxicometabolomics". Trabalho apresentado em EUROTOX,
2021.
- Araújo, Ana Margarida; Márcia Cláudia Dias de Carvalho; Costa, Vera Marisa; Duarte, José Alberto; Dinis-Oliveira, Ricardo
Jorge; Bastos, Maria de Lourdes; Maria Paula do Amaral Alegria Guedes de Pinho; Carvalho, Félix. "A translational in vitro
and in vivo metabolomics study reveals altered hepatic metabolic pathways after acute exposure to 3,4-methylenedioxypyrovalerone".
Trabalho apresentado em 17th Annual Conference of Metabolomics Society, 2021.
- Ana Ares Fuentes; Araújo, Ana Margarida; Filipa Amaro; AR Lorenzo; AM Carro; P Fernández; Bastos, Maria de Lourdes; Maria
Paula do Amaral Alegria Guedes de Pinho. "Cytotoxicity studies of synthetic cathinones in a human renal cell model". Trabalho
apresentado em VIII Encontro da Mocidade Investigadora da Universidade de Santiago de Compostela, 2021.
- Araújo, Ana Margarida; Márcia Cláudia Dias de Carvalho; Costa, Vera Marisa; Duarte, José Alberto; Dinis-Oliveira, Ricardo
Jorge; Bastos, Maria de Lourdes; de Pinho, Paula Guedes; Carvalho, Félix. "Application of in vivo metabolomics to evaluate
the early pathways of toxicity triggered by human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV)". Trabalho apresentado
em 16th Annual Conference of Metabolomics Society - Metabolomics Online 2020, 2020.
- Enea, Maria; Araújo, Ana Margarida; Bastos, Maria de Lourdes; Carmo, Helena; Pereira, Eulália. "The effect of star- and sphere-shaped
gold nanoparticles on human kidney HK-2 cells". Trabalho apresentado em IV International Caparica Symposium on Nanoparticles/Nanomaterials
and Applications 2020, 2020.
- Araújo, Ana Margarida; Enea, Maria; Fernandes, Eduarda; Bastos, Maria de Lourdes; Carvalho, Félix; Guedes de Pinho, Paula;
Carvalho, Márcia. "A new strategy for exploring the role of hyperthermia in MDMA-induced toxicity in primary mouse hepatic
cells using GC-MS-based metabolomics". Trabalho apresentado em 55th European Congress of the European Societies of the
Toxicology (EUROTOX2019), 2019.
- Enea, Maria; Araújo, Ana Margarida; Guedes de Pinho, Paula; Pereira, Eulália; Bastos, Maria de Lourdes; Carmo, Helena. "A
metabolomic study of the effect of gold nanostars vs gols nanospheres in Wistar rats after a single dose intravenous administration".
Trabalho apresentado em 55th European Congress of the European Societies of the Toxicology (EUROTOX2019), 2019.
- Araújo, Ana Margarida; Fernandes, Eduarda; Bastos, Maria de Lourdes; Carvalho, Félix; Guedes de Pinho, Paula; Carvalho, Márcia.
"Use of metabolomics for exploring early mechanisms of hepatotoxicity triggered by amphetamine-like drugs". Trabalho apresentado
em 15th Annual Conference of Metabolomics Society (Metabolomics 2019), 2019.
- Araújo, Ana Margarida; Bastos, Maria de Lourdes; Fernandes, Eduarda; Carvalho, Félix; Carvalho, Márcia; Guedes de Pinho, Paula.
"Characterization of hepatic metabolic disturbances caused by subtoxic levels of 3,4-methylenedioxymethamphetamine (MDMA)".
Trabalho apresentado em UCIBIO Annual Meeting, 2018.
- Lima, Ana Rita; Araújo, Ana Margarida; Pinto, Joana; Jerónimo, Carmen; Henrique, Rui; Bastos, Maria de Lourdes; Carvalho,
Márcia; Guedes de Pinho, Paula. "Evaluation of prostate cancer volatilome: an in vitro approach". Trabalho apresentado em
UCIBIO Annual Meeting, 2018.
- Araújo, Ana Margarida; Bastos, Maria de Lourdes; Carvalho, Félix; Carvalho, Márcia; Guedes de Pinho, Paula. "Metabolomic analysis
of the toxicity pathways elicited by subtoxic concentrations of methylone in primary mouse hepatocytes". Trabalho apresentado
em 54th European Congress of the European Societies of the Toxicology (EUROTOX2018), 2018.
- Carvalho, Tiago; Vaz, Isa; Araújo, Ana Margarida; Remião, Fernando; Bastos, Maria de Lourdes; Carvalho, Márcia. "Toxicity
of synthetic cathinones in human kidney (HK-2) cells". Trabalho apresentado em 54th European Congress of the European Societies
of the Toxicology (EUROTOX2018), 2018.
- Vaz, Isa; Castro, Ana; Araújo, Ana Margarida; Valente, Maria João; Guedes de Pinho, Paula; Bastos, Maria de Lourdes; Carvalho,
Márcia. "Autophagy plays a protective role in synthetic cathinones-induced nephrotoxicity". Trabalho apresentado em 54th
European Congress of the European Societies of the Toxicology (EUROTOX2018), 2018.
- Lima, Ana Rita; Araújo, Ana Margarida; Pinto, Joana; Jerónimo, Carmen; Henrique, Rui; Bastos, Maria de Lourdes; Carvalho,
Márcia; Guedes de Pinho, Paula. "Evaluation of prostate cancer volatilome: an in vitro approach". Trabalho apresentado em
54th European Congress of the European Societies of the Toxicology (EUROTOX2018), 2018.
- Araújo, Ana Margarida; Lima, Ana Rita; Bastos, Maria de Lourdes; Carvalho, Félix; Carvalho, Márcia; Guedes de Pinho, Paula.
"Effect of subtoxic and toxic concentrations of galactosamina in the metabolome of primary mouse hepatocytes". Trabalho apresentado
em 53rd European Congress of the European Societies of the Toxicology (EUROTOX2017), 2017.
- Santos Carvalho, A.; Fontes, A.; Santos, N.; Araújo, A.M.; Guedes de Pinho, P.; Cavadas, C.; Carvalho, F.; Ferreira, S.. "Unravelling
the mechanisms of neuronal, hepatic, cardiac and renal cell toxicity of two synthetic cannabinoids, 5F-PB 22 and XLR-11".
Trabalho apresentado em 53rd European Congress of the European Societies of the Toxicology (EUROTOX2017), 2017.
- Valente, Maria João; Araújo, Ana Margarida; Silva, Renata; Amaral, Cristina; Silva, Georgina; Duarte, José Alberto; Fernandes,
Eduarda; et al. "In vitro toxicity of ß-keto amphetamines mechanistic studies in hepatic and neuronal cell models". Trabalho
apresentado em UCIBIO Advisory Board Member, 2017.
- Araújo, Ana Margarida; Valente, Maria João; Dias da Silva, Diana; Carvalho, Márcia; Carvalho, Félix; Bastos, Maria de Lourdes.
"‘Smart’ but not safe: the potential hepatotoxicity of synthetic cathinones". Trabalho apresentado em I Encontro Annual
do Departamento de Ciências Biológicas da Faculdade de Farmácia da Universidade do Porto, 2016.
- Calejo, Isabel; Araújo, Ana Margarida; Moreira, Nathalie; Jerónimo, Carmen; Henrique, Rui; Bastos, Maria de Lourdes; Carvalho,
Márcia; Guedes de Pinho, Paula. "A GC-MS methodology for the determination of potential urinary volatile carbonyl as biomarkers
of prostate cancer". Trabalho apresentado em I Encontro Annual do Departamento de Ciências Biológicas da Faculdade de Farmácia
da Universidade do Porto, 2016.
- Calejo, Isabel; Moreira, Nathalie; Araújo, Ana Margarida; Carvalho, Márcia; Bastos, Maria de Lourdes; Guedes de Pinho, Paula.
"Development and optimisation of a GC methodology with PFBHA derivatization for the determination of volatile carbonyl metabolites
in urine of smokers and non-smokers". Trabalho apresentado em I Encontro Annual do Departamento de Ciências Biológicas
da Faculdade de Farmácia da Universidade do Porto, 2016.
- Bastos, Maria de Lourdes; Valente, Maria João; Araújo, Ana Margarida; Carvalho, Félix; Guedes de Pinho, Paula; Carvalho, Márcia.
"Synthetic cathinones: unveiling the mechanisms for liver injury". Trabalho apresentado em 55th Annual meeting and ToxExpo
(SOT2016), 2016.
- Calejo, Isabel; Moreira, Nathalie; Araújo, Ana Margarida; Carvalho, Márcia; Moreira Barbosa, Catarina; Jerónimo, Carmen; Henrique,
Rui; Bastos, Maria de Lourdes; Guedes de Pinho, Paula. "Development of an analytical method with PFBHA derivatization followed
by headspace SPME-GC/MS for the determination of urinary volatile carbonyl metabolites in patients with prostate cancer".
Trabalho apresentado em 51st Congress of the European Societies of Toxicology (EUROTOX 2015), 2015.
- Valente, Maria João; Araújo, Ana Margarida; Silva, Renata; Bastos, Maia de Lourdes; Carvalho, Félix; Guedes de Pinho, Paula;
Carvalho, Márcia. "Is hyperthermia the triggering factor for hepatotoxicity induced by ‘bath salts’? An in vitro study using
primary cultured rat hepatocytes". Trabalho apresentado em 51st Congress of the European Societies of Toxicology (EUROTOX
2015), 2015.
- Valente, Maria João; Araújo, Ana Margarida; Silva, Renata; Bastos, Maria de Lourdes; Carvalho, Félix; Guedes de Pinho, Paula;
Carvalho, Márcia. "Hepatic oxidative stress induced by methylone and MDPV: a comparison to MDMA". Trabalho apresentado em
51st Congress of the European Societies of Toxicology (EUROTOX 2015), 2015.
- Dias da Silva, Diana; Silva, Maria João; Araújo, Ana Margarida; Valente, Maria João; Carmo, Helena. "Mixtures of benzylpiperazine
(BZP) and 3-trifluoromethylphenylpiperazine (TFMPP) elicit hepatotoxic effects in human HepaRG cells and primary rat hepatocytes".
Trabalho apresentado em 51st Congress of the European Societies of Toxicology (EUROTOX 2015), 2015.
- Bastos, Maria de Lourdes; Valente, Maria João; Araújo, Ana Margarida; Carvalho, Félix; Guedes de Pinho, Paula; Carvalho, Márcia.
"Hyperthermia exacerbates MDPV-induced hepatic oxidative stress". Trabalho apresentado em 54th Annual meeting and ToxExpo
(SOT2015), 2015.
- Araújo, Ana Margarida; Valente, Maria João; Dias da Silva, Diana; Carvalho, Márcia; Carvalho, Félix; Bastos, Maria de Lourdes;
Guedes de Pinho, Paula. "'Smart' but not safe: the potential hepatotoxicity of synthetic cathinones". Trabalho apresentado
em 50th Congress of the European Societies of Toxicology (EUROTOX 2014), 2014.
- Valente, Maria João; Araújo, Ana Margarida; Carvalho, Félix; Bastos, Maria de Lourdes; Guedes de Pinho, Paula; Carvalho, Márcia.
"An insight into the mechanisms underlying the hepatotoxicity of cathinone derivatives". Trabalho apresentado em 50th Congress
of the European Societies of Toxicology (EUROTOX 2014), 2014.
- Araújo, Ana Margarida; Bastos, Maria de Lourdes; Carvalho, Márcia; Carvalho, Félix; Gaspar, Helena; Cardoso Matias, Ana; Guedes
de Pinho, Paula. "Identification of psychoactive substances in “legal highs” marketed in Portugal". Trabalho apresentado em
49th Congress of the European Societies of Toxicology (EUROTOX 2013), 2013.
- Araújo, Ana Margarida; Bastos, Maria de Lourdes; Carvalho, Márcia; Carvalho, Félix; Gaspar, Helena; Cardoso Matias, Ana; Guedes
de Pinho, Paula. "Chemical characterization of “legal highs” marketed in Portuguese ‘smartshops’". Trabalho apresentado em
12th National Congress of Legal Medicine and Forensic Sciences, 2013.
- Silva, Paulo; Agasse, Alice; Conde, Artur; Araújo, Ana Margarida; Delrot, S; Tavares, Rui; Gerós, Hernâni. "Identification,
cloning and characterization of a Olea europaea mannitol dehydrogenase (OeMTD1) and its involvement in salt stress tolerance".
Trabalho apresentado em XVI National Congress of Biochemistry, 2008.
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Recurso online |
- Dionísio, Flávio; Araújo, Ana Margarida; Duarte-Araújo, Margarida; Guedes de Pinho, Paula; Bastos, Maria de Lourdes; Carvalho,
Félix; Costa, Vera Marisa. Cyclophosphamide main bioactivation products cause disturbance in the metabolome of AC16 cardiac
cells at clinically relevant concentrations. 2019. https://sciforum.net/paper/view/conference/6366.
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Resumo em conferência |
- Dias-Carvalho, A.; Araújo, A. M.; Reis-Mendes, A.; Sequeira, C. Oliveira; Pereira, S. Azeredo; de Pinho, P. Guedes; Carvalho,
F.; et al. "Mitoxantrone disrupts brain glutathione defense and the metabolic pathways in CD-1 mice". Trabalho apresentado
em EUROTOX, 2024, 2024.
Publicado • 10.1016/j.toxlet.2024.07.397
- Araújo, Ana Margarida; Ramos, Helena; Ribeiro, Mafalda; Martins, Zita; Marin-Saez, Jesus; Lopez-Ruiz, Rosalia; Faria, Miguel
A.; Ferreira, Isabel M. P. L. V. O.. "Examining the impact of a realistic mixture of dietary contaminants on the intestinal
barrier and compound absorption". Trabalho apresentado em EUROTOX, 2024, 2024.
Publicado • 10.1016/j.toxlet.2024.07.857
- Mota, Carolina; Martins, Zita; Ramos, Helena; Ferreira, Isabel M. P. L. V. O.; Carvalho, Márcia; Araújo, Ana Margarida. "The
unseen ingredients: a systematic review of the prevalence of microplastics and nano plastics in our food". Trabalho apresentado
em III 1H-TOXRUN International Congress, 2024.
Publicado • 10.48797/sl.2024.261
- Valente, Maria João; Araújo, Ana Margarida; Carvalho, Félix; Carvalho, Márcia. "Toxicity of amphetamine-type drugs in rat
cardiomyocyte cells involves oxidative stress and the formation of acidic vesicular organelles". Trabalho apresentado em II
TOXRUN International Congress 2023 - No Boundaries for Toxicology: One Health, One Society, One Planet, Porto,
2023.
Publicado • https://doi.org/10.48797/sl.2023.100
- Sousa, Débora; Amaro, Filipa; Araújo, Ana Margarida; Carvalho, Márcia. "Impact of cannabidiol on viability of normal and tumorigenic
human kidney cells: are the effects serum-dependent?". Trabalho apresentado em II TOXRUN International Congress 2023 -
No Boundaries for Toxicology: One Health, One Society, One Planet, Porto, 2023.
Publicado • https://doi.org/10.48797/sl.2023.29
- Sousa, Bárbara; Araújo, Ana Margarida; Guimarães, Inês; Rato, Fátima; Carvalho, Márcia. "Impact of COVID-19 pandemic on the
patterns of toxic exposure: a retrospective analysis of Portuguese poison centre database". Trabalho apresentado em I TOXRUN
International Congress 2022, Porto, 2022.
Publicado • https://doi.org/10.51126/revsalus.v4iSup.383
- Amaro, F.; Pinto, Joana; Rocha, Sílvia; Araújo, Ana Margarida; Miranda-Gonçalves, Vera; Jerónimo, Carmen; Henrique, Rui; et
al. "In vitro volatile exometabolome signature of clear cell renal cell carcinoma". Trabalho apresentado em EUROTOX,
2021.
Publicado • 10.1016/S0378-4274(21)00497-5
- Araújo, Ana Margarida; Márcia Cláudia Dias de Carvalho; Costa, Vera Marisa; Duarte, José Alberto; Dinis-Oliveira, Ricardo
Jorge; Bastos, Maria de Lourdes; Guedes de Pinho, Paula; Carvalho, Félix. "Early pathways of toxicity triggered by 3,4-methylenedioxypyrovalerone
(MDPV) unveiled by in vivo toxicometabolomics". Trabalho apresentado em EUROTOX, 2021.
Publicado • 10.1016/S0378-4274(21)00553-1
- Dionísio, Flávio; Araújo, Ana Margarida; Araújo, Margarida Duarte; de Pinho, Paula Guedes; Bastos, Maria de Lourdes; Carvalho,
Félix; Costa, Vera Marisa. "The main products of cyclophosphamide bioactivation exert a cardiotoxic effect at clinical important
concentrations in AC16 cardiac cells". Trabalho apresentado em 5th International Electronic Conference on Medical Chemistry,
2019.
Publicado • 10.3390/ecmc2019-06366
- Enea, Maria; Araújo, Ana Margarida; Guedes de Pinho, Paula; Pereira, Eulália; Bastos, Maria de Lourdes; Carmo, Helena. "A
metabolomic study of the effect of gold nanostars vs gols nanospheres in Wistar rats after a single dose intravenous administration".
Trabalho apresentado em 55th European Congress of the European Societies of the Toxicology (EUROTOX2019), Helsinki,
2019.
Publicado • 10.1016/j.toxlet.2019.09.002
- Araújo, Ana Margarida; Enea, Maria; Fernandes, Eduarda; Bastos, Maria de Lourdes; Carvalho, Félix; de Pinho, Paula Guedes;
Márcia Cláudia Dias de Carvalho. "A new strategy for exploring the role of hyperthermia in MDMA-induced toxicity in primary
mouse hepatic cells using GC-MS-based metabolomics". Trabalho apresentado em 55th European Congress of the European Societies
of the Toxicology (EUROTOX2019), Helsinki, 2019.
Publicado • 10.1016/j.toxlet.2019.09.002
- Lima, Ana Rita; Araújo, Ana Margarida; Pinto, Joana; Jerónimo, Carmen; Henrique, Rui; Bastos, Maria de Lourdes; Carvalho,
Márcia; Guedes de Pinho, Paula. "Evaluation of prostate cancer volatilome: an in vitro approach". Trabalho apresentado em
Eurotox, Brussels, 2018.
Publicado • 10.1016/j.toxlet.2018.07.028
- Vaz, Isa; Castro, Ana; Araújo, Ana Margarida; Valente, Maria João; Guedes de Pinho, Paula; Bastos, Maria de Lourdes; Carvalho,
Márcia. "Autophagy plays a protective role in synthetic cathinones-induced nephrotoxicity". Trabalho apresentado em Eurotox,
Brussels, 2018.
Publicado • 10.1016/j.toxlet.2018.06.867
- Carvalho, Tiago; Vaz, Isa; Araújo, Ana Margarida; Remião, Fernando; Bastos, Maria de Lourdes; Carvalho, Márcia. "Toxicity
of synthetic cathinones in human kidney (HK-2) cells". Trabalho apresentado em Eurotox, Brussels, 2018.
Publicado • 10.1016/j.toxlet.2018.06.996
- Araújo, Ana Margarida; Bastos, Maria de Lourdes; Carvalho, Félix; Carvalho, Márcia; Guedes de Pinho, Paula. "Metabolomic analysis
of the toxicity pathways elicited by subtoxic concentrations of methylone in primary mouse hepatocytes". Trabalho apresentado
em Eurotox, Brussels, 2018.
Publicado • 10.1016/j.toxlet.2018.07.026
- Araújo, Ana Margarida; Lima, Ana Rita; Bastos, Maria de Lourdes; Carvalho, Félix; Carvalho, Márcia; Guedes de Pinho, Paula.
"Effect of subtoxic and toxic concentrations of galactosamine in the metabolome of primary mouse hepatocytes". Trabalho apresentado
em Eurotox, Bratislava, 2017.
Publicado • http://dx.doi.org/10.1016/j.toxlet.2017.07.828
- Santos Carvalho, Ana; Fontes, Adriana; Araújo, Ana Margarida; Santos, Nuno; Guedes de Pinho, Paula; Cavadas, Cláudia; Carvalho,
Félix; Ferreira, Sónia. "Unravelling the mechanisms of neuronal, hepatic, cardiac and renal cell toxicity of two synthetic
cannabinoids, 5F-PB 22 and XLR-11". Trabalho apresentado em Eurotox, Bratislava, 2017.
Publicado • http://dx.doi.org/10.1016/j.toxlet.2017.07.239
- Dias da Silva, Diana; Silva, Maria João; Araújo, Ana Margarida; Valente, Maria João; Carmo, Helena. "Mixtures of benzylpiperazine
(BZP) and 3-trifluoromethylphenylpiperazine (TFMPP) elicit hepatotoxic effects in human HepaRG cells and primary rat hepatocytes".
Trabalho apresentado em EUROTOX, Porto, 2015.
Publicado • 10.1016/j.toxlet.2015.08.1012
- Valente, Maria João; Araújo, Ana Margarida; Silva, Renata; Bastos, Maria de Lourdes; Carvalho, Félix; Guedes de Pinho, Paula;
Carvalho, Márcia. "Hepatic oxidative stress induced by methylone and MDPV: a comparison to MDMA". Trabalho apresentado em
EUROTOX, Porto, 2015.
Publicado • 10.1016/j.toxlet.2015.08.765
- Valente, Maria João; Araújo, Ana Margarida; Silva, Renata; Bastos, Maria de Lourdes; Carvalho, Félix; Guedes de Pinho, Paula;
Carvalho, Márcia. "Is hyperthermia the triggering factor for hepatotoxicity induced by ‘bath salts’? An in vitro study using
primary cultured rat hepatocytes". Trabalho apresentado em Eurotox, Porto, 2015.
Publicado • 10.1016/j.toxlet.2015.08.752
- Calejo, Isabel; Moreira, Nathalie; Araújo, Ana Margarida; Carvalho, Márcia; Moreira Barbosa, Catarina; Jerónimo, Carmen; Henrique,
Rui; Bastos, Maria de Lourdes; Guedes de Pinho, Paula. "Development of an analytical method with PFBHA derivatization followed
by headspace SPME-GC/MS for the determination of urinary volatile carbonyl metabolites in patients with prostate cancer".
Trabalho apresentado em Eurotox, Porto, 2015.
Publicado • 10.1016/j.toxlet.2015.08.686
- Valente, Maria João; Araújo, Ana Margarida; Carvalho, Félix; Bastos, Maria de Lourdes; Guedes de Pinho, Paula; Carvalho, Márcia.
"An insight into the mechanisms underlying the hepatotoxicity of cathinone derivatives". Trabalho apresentado em EUROTOX,
Edinburgh, 2014.
Publicado • 10.1016/j.toxlet.2014.06.235
- Araújo, Ana Margarida; Valente, Maria João; Dias da Silva, Diana; Carvalho, Márcia; Carvalho, Félix; Bastos, Maria de Lourdes;
Guedes de Pinho, Paula. "‘Smart’ but not safe: The potential hepatotoxicity of synthetic cathinones". Trabalho apresentado
em EUROTOX, Edinburgh, 2014.
Publicado • 10.1016/j.toxlet.2014.06.254
- Araújo, Ana Margarida; Bastos, Maria de Lourdes; Carvalho, Márcia; Carvalho, Félix; Gaspar, Helena; Cardoso Matias, Ana; Guedes
de Pinho, Paula. "Identification of psychoactive substances in “legal highs” marketed in Portugal". Trabalho apresentado em
EUROTOX, Interlaken, 2013.
Publicado • 10.1016/j.toxlet.2013.05.423
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Tese / Dissertação |
- Araújo, Ana Margarida. "Toxicometabolomics of amphetamines derivatives in in vitro and in vivo models". Doutoramento, Universidade
do Porto Faculdade de Farmácia, 2021. https://hdl.handle.net/10216/133680.
- Araújo, Ana. "Psychoactive substances present in ‘legal highs’ acquired in ‘smartshops’ or via Internet: chemical characterization
and in vitro cytotoxicity studies of synthetic cathinones". Mestrado, Universidade do Porto Faculdade de Medicina, 2013. https://repositorio-aberto.up.pt/handle/10216/77085.
- Araújo, Ana. "Study of mechanisms underlying of Olea europaea to salt and drought. Extraction and analysis of phenolics".
Licenciatura, Universidade do Minho, 2008.
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