???global.info.a_carregar???
In 2006, I received my Ph.D. in Evolutionary Biology from the University of Lisbon (as a visiting Ph.D. student at the Service de Systématique Moléculaire, Muséum National d'Histoire Naturelle in Paris, France, and the Institute of Animal Physiology and Genetics in Libechov, Czech Republic). I am a Researcher at iMM working in clinical and translational research in the area of neurodegenerative disorders particularly, motor neuron diseases. I have over 20 years of experience in scientific research in diverse fields: i) clinical neurosciences & neurology; ii) genetics heredity; iii) computer science; iv) oncology and drug resistance; v) evolutionary biology; vi) molecular biology. I have co-authored more than 100 works including 89 indexed in Scopus, h-index = 16 (Google Scholar: h-index=18, i10=33). My work has a Research Interest Score higher than 90% of ResearchGate members. I have participated in 12 R&D projects funded by national and European agencies including, presently, a Horizon 2020 project: Brainteaser. I have been developing collaborations with a diverse network of research teams nationally and internationally. Moreover, I have technical and management expertise (data analysis, project and data management, leadership, teaching, and supervising). I was awarded one prize, four fellowships, and a Ciência 2008 contract. I am a tutor of a Ph.D. student and supervised five MSc students and several undergraduate students. I've taught in one MSc program and two PhD programs. I have been an expert reviewer for 16 international journals.
Ler resumo completo ↓
Identificação

Identificação pessoal

Nome completo
Marta Luísa Gromicho Morgado Silva

Nomes de citação

  • Marta Gromicho

Identificadores de autor

Ciência ID
EA1D-1979-5C3A
ORCID iD
0000-0003-2111-4579
Researcher Id
B-2171-2018
Scopus Author Id
6506583274

Endereços de correio eletrónico

  • martalgms@gmail.com (Profissional)
  • mgromichosilva@medicina.ulisboa.pt (Profissional)

Moradas

  • Instituto de Medicina Molecular. Avenida Professor Egas Moniz, 1649-¿028, Lisbon, Lisboa, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde
  • Ciências Médicas e da Saúde
  • Ciências Naturais - Ciências Biológicas - Biologia da Evolução das Espécies

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2006
Concluído
 Biologia (Doutoramento)
Especialização em Especialidade: Biologia Evolutiva
Universidade de Lisboa, Portugal
"Genome Polyploidisation in the Iberian Fish Complex Squalius Alburnoides. a Case Study of Evolution-in-action Through Hybridisation and No-sexuality: a Cytogenetic Approach" (TESE/DISSERTAÇÃO)
1998
Concluído
 Biologia Aplicada aos Recursos Animais, Variante Marinhos (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"O teste de micronúcleos na pesquisa de efeitos genotoxicológicos da acumulação de metais pesados em peixes" (TESE/DISSERTAÇÃO)
 16 out of 20
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2018/08/01 - Atual Investigador Contratado (Investigação) Instituto de Medicina Molecular, Portugal
2015/07/01 - 2018/07/31 Pós-doutorado (Investigação) Instituto de Medicina Molecular, Portugal
2009/07/01 - 2014/06/30 Investigador Contratado (Investigação) Universidade Nova de Lisboa Centro de Toxicogenómica e Saúde Humana, Portugal
2008/04/01 - 2009/06/30 Pós-doutorado (Investigação) Universidade Nova de Lisboa Centro de Toxicogenómica e Saúde Humana, Portugal
2000/09/01 - 2004/08/31 Investigador (Investigação) Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Lisboa Faculdade de Ciências, Portugal
2004/02/01 - 2004/03/01 Estagiário de Investigação (Investigação) Muséum National d'Histoire Naturelle, França
Muséum National d'Histoire Naturelle, França
2003/03/01 - 2003/04/01 Estagiário de Investigação (Investigação) Muséum National d'Histoire Naturelle, França
Muséum National d'Histoire Naturelle, França
2001/02/01 - 2001/03/01 Estagiário de Investigação (Investigação) Laboratory of Fish Genetics, Institute of Animal Physiology and Genetics of Libechov, República Checa
Laboratory of Fish Genetics, Institute of Animal Physiology and Genetics of Libechov, República Checa

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2007/03/01 - 2008/03/31 Orthopaedic sales representative Salgado Orthopaedics - Artur Salgado, SA., Portugal
2004/09/01 - 2005/06/30 Consultant Fluviatilis, Consultoria Ambiental Lda., Portugal
Projetos

Projeto

Designação Financiadores
2021/01/01 - 2024/12/31 BRAINTEASER - Bringing Artificial Intelligence home for a better care of amyotrophic lateral sclerosis and multiple sclerosis
GA101017598
Investigador
Instituto de Medicina Molecular, Portugal
 Horizon 2020 European Innovation Council Fast Track to Innovation
Em curso
2021/03/01 - 2024/02/28 AIpALS - Modelos Avançados de aprendIzagem para a Previsão do prognóstico na ELA usando perfis de doentes e padrões de progressão da doença
PTDC/CCI-CIF/4613/2020
Investigador
Fundação para a Ciência e a Tecnologia
Em curso
2018/10/04 - 2021/10/03 Avaliação detalhada de microRNA circulantes como biomarcadores de diagnóstico e prognóstico em Esclerose Lateral Amiotrófica
PTDC/MEC-NEU/31195/2017
Instituto de Medicina Molecular, Portugal

Universidade Nova de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2016/07/01 - 2020/03/31 NEUROCLINOMICS2 - Descoberta de marcardores de prognóstico em doenças neurodegenerativas através da integracção de dados clínicos e genómicos
PTDC/EEI-SII/1937/2014
Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento em Lisboa, Portugal

Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento em Lisboa, Portugal

Instituto de Medicina Molecular, Portugal

Instituto de Telecomunicações, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2015/03/01 - 2018/12/31 Base de Dados Web baseada na Ontologia para Compreeender a Esclerose Lateral Amiotrófica
JPND-PS/0001/2013
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2007/08/01 - 2011/04/15 Mecanismos de Resistência ao Imatinib em Leucemia Mielóide Crónica
PTDC/SAU-GMG/71720/2006
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2005/07/01 - 2006/12/31 Estudo de um caso de hibridação introgressiva em peixes ibéricos - um novo paradigma para a biologia evolutiva?
POCI/BIA-BDE/57805/2004
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal

Universidade de Lisboa Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2002/09/01 - 2006/09/30 Estudo da estrutura genética, dinâmica e potencial evolutivo do complexo hibridogenético Leuciscus alburnoides, através de marcadores moleculares
POCTI/BSE/40868/2001
 Fundação para a Ciência e a Tecnologia
Concluído
2001/01/01 - 2003/01/31 A hibridação e a unissexualidade na evolução de um complexo ibérico de peixes: uma abordagem genética e ecológica
POCTI/BIA/11086/2001
 Fundação para a Ciência e a Tecnologia
Concluído

Outro

Designação Financiadores
2016/01/01 - Atual Project MinE: Make it yours!
Project MinE
Investigador
Em curso
2010/04/01 - Atual Biodiversity4All - Associação Biodiversidade Para Todos
BioDiversity4All
Outra
Associação Biodiversidade para Todos - BioDiversity4all, Portugal
Em curso
Produções

Publicações

Artigo em conferência
  1. Alessandro Guazzo; Isotta Trescato; Enrico Longato; Enidia Hazizaj; Dennis Dosso; Guglielmo Faggioli; Giorgio Maria Di Nunzio; et al. "Intelligent Disease Progression Prediction: Overview of iDPP@CLEF 2022". 2022.
    10.1007/978-3-031-13643-6_25
  2. Marta Gromicho. "Peripheral neuropathy in ALS: Phenotype association". 2018.
    https://doi.org/10.1111/jns.12290
  3. Marta Gromicho. "Predicting Non-invasive Ventilation in ALS Patients Using Stratified Disease Progression Groups". 2018.
    10.1109/icdmw.2018.00113
  4. Marta Gromicho. "Development and External Validation of a Prognostic Model Estimating Survival in Individual ALS Patients.". 2016.
    10.1080/21678421.2016.1231971
  5. Marta Gromicho. "Role of ABC transporters in the development of Imatinib resistance". 2009.
Artigo em revista
  1. Susana Pinto; Miguel Oliveira Santos; Marta Gromicho; Michael Swash; Mamede de Carvalho. "Impact of diabetes mellitus on the respiratory function of amyotrophic lateral sclerosis patients". European Journal of Neurology (2024): https://doi.org/10.1111/ene.16129.
    10.1111/ene.16129
  2. Inês Alves; Marta Gromicho; Miguel Oliveira Santos; Susana Pinto; Ana Pronto-Laborinho; Michael Swash; Mamede de Carvalho. "Demographic changes in a large motor neuron disease cohort in Portugal: a 27 year experience". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration (2023): https://doi.org/10.1080/21678421.2023.2220747.
    10.1080/21678421.2023.2220747
  3. Erica Tavazzi; Enrico Longato; Martina Vettoretti; Helena Aidos; Isotta Trescato; Chiara Roversi; Andreia S. Martins; et al. "Artificial intelligence and statistical methods for stratification and prediction of progression in amyotrophic lateral sclerosis: A systematic review". Artificial Intelligence in Medicine (2023): 102588-102588. http://dx.doi.org/10.1016/j.artmed.2023.102588.
    10.1016/j.artmed.2023.102588
  4. Diogo F. Soares; Rui Henriques; Marta Gromicho; Mamede de Carvalho; Sara C. Madeira. "Triclustering-based classification of longitudinal data for prognostic prediction: targeting relevant clinical endpoints in amyotrophic lateral sclerosis". Scientific Reports 13 1 (2023): http://dx.doi.org/10.1038/s41598-023-33223-x.
    10.1038/s41598-023-33223-x
  5. Miguel Oliveira Santos; Marta Gromicho; Susana Pinto; Ana Catarina Pronto-Laborinho; Mamede de Carvalho. "Clinical characteristics in amyotrophic lateral sclerosis with Sub-Saharan Africa ancestry – A Portuguese hospital-based cohort study". Clinical Neurology and Neurosurgery (2023): https://doi.org/10.1016/j.clineuro.2023.107674.
    10.1016/j.clineuro.2023.107674
  6. Ana Rita Oliveira Henriques; Marta Gromicho; Julian Grosskreutz; Magdalena Kuzma-Kozakiewicz; Susanne Petri; Hilmi Uysal; Susana Pinto; et al. "Association of the practice of contact sports with the development of amyotrophic lateral sclerosis". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration (2023): 1-8. http://dx.doi.org/10.1080/21678421.2023.2189911.
    10.1080/21678421.2023.2189911
  7. Susana Pinto; Miguel Oliveira Santos; Marta Gromicho; Michael Swash; Mamede de Carvalho. "Respiratory phenotypes in amyotrophic lateral sclerosis as determined by respiratory questions on the Amyotrophic Lateral Sclerosis Functional Rating Scale–Revised and their relation to respiratory tests". European Journal of Neurology (2023): https://doi.org/10.1111/ene.15765.
    10.1111/ene.15765
  8. Miguel Oliveira Santos; Marta Gromicho; Ana Pronto-Laborinho; Mamede de Carvalho. "Sporadic Spinal-Onset Amyotrophic Lateral Sclerosis Associated with Myopathy in Three Unrelated Portuguese Patients". Brain Sciences (2023): https://doi.org/10.3390/brainsci13020220.
    10.3390/brainsci13020220
  9. Falcão de Campos, Catarina; Gromicho, Marta; Uysal, Hilmi; Grosskreutz, Julian; Kuzma-Kozakiewicz, Magdalena; Oliveira Santos, Miguel; Pinto, Susana; et al. "Trends in the diagnostic delay and pathway for amyotrophic lateral sclerosis patients across different countries". Frontiers in Neurology 13 (2023): http://dx.doi.org/10.3389/fneur.2022.1064619.
    10.3389/fneur.2022.1064619
  10. Marta Gromicho; Miguel Oliveira Santos; Susana Pinto; Michael Swash; Mamede De Carvalho. "The flail-arm syndrome: the influence of phenotypic features". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration (2023): https://doi.org/10.1080/21678421.2022.2164205.
    10.1080/21678421.2022.2164205
  11. Schön, M.; Oliveira Santos, M.; Gromicho, M.; Pinto, S.; Swash, M.; de Carvalho, M.. "Wasted leg syndrome: An atypical slowly-progressive form of lower motor neuron disease". Revue Neurologique 179 1-2 (2023): 114-117. http://dx.doi.org/10.1016/j.neurol.2022.09.007.
    10.1016/j.neurol.2022.09.007
  12. Oliveira Santos, Miguel; Gromicho, Marta; Pinto, Susana; Swash, Michael; de Carvalho, Mamede. "Mild dysphagia does not influence survival in ventilated amyotrophic lateral sclerosis patients". Journal of the Neurological Sciences 442 (2022): 120388. http://dx.doi.org/10.1016/j.jns.2022.120388.
    10.1016/j.jns.2022.120388
  13. Diogo F. Soares; Rui Henriques; Marta Gromicho; Mamede de Carvalho; Sara C. Madeira. "Learning prognostic models using a mixture of biclustering and triclustering: Predicting the need for non-invasive ventilation in Amyotrophic Lateral Sclerosis". Journal of Biomedical Informatics (2022): https://doi.org/10.1016/j.jbi.2022.104172.
    10.1016/j.jbi.2022.104172
  14. Andreia S. Martins; Marta Gromicho; Susana Pinto; Mamede de Carvalho; Sara C. Madeira; Martins, Andreia S.; Gromicho, Marta; et al. "Learning Prognostic Models Using Disease Progression Patterns: Predicting the Need for Non-Invasive Ventilation in Amyotrophic Lateral Sclerosis". IEEE/ACM Transactions on Computational Biology and Bioinformatics 19 5 (2022): 2572-2583. https://doi.org/10.1109/TCBB.2021.3078362.
    10.1109/TCBB.2021.3078362
  15. Cláudia Santos Silva; Marta Gromicho; Miguel Oliveira Santos; Susana Pinto; Michael Swash; Mamede de Carvalho. "Thyroid dysfunction in Portuguese amyotrophic lateral sclerosis patients". Neurological Sciences (2022): https://doi.org/10.1007/s10072-022-06135-3.
    10.1007/s10072-022-06135-3
  16. Marta Gromicho; Tiago Leão; Miguel Oliveira Santos; Susana Pinto; Alexandra M. Carvalho; Sara C. Madeira; Mamede De Carvalho. "Dynamic Bayesian networks for stratification of disease progression in amyotrophic lateral sclerosis". European Journal of Neurology (2022): https://doi.org/10.1111/ene.15357.
    10.1111/ene.15357
  17. Hertel, Nora; Kuzma-Kozakiewicz, Magdalena; Gromicho, Marta; Grosskreutz, Julian; de Carvalho, Mamede; Uysal, Hilmi; Dengler, Reinhard; Petri, Susanne; Körner, Sonja. "Analysis of routine blood parameters in patients with amyotrophic lateral sclerosis and evaluation of a possible correlation with disease progression—a multicenter study". Frontiers in Neurology 13 (2022): http://dx.doi.org/10.3389/fneur.2022.940375.
    10.3389/fneur.2022.940375
  18. Susana Pinto; Marta Gromicho; Miguel Oliveira Oliveira Santos; Michael Swash; Mamede De Carvalho. "Respiratory onset in amyotrophic lateral sclerosis: clinical features and spreading pattern". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration (2022): https://doi.org/10.1080/21678421.2022.2067777.
    10.1080/21678421.2022.2067777
  19. Oliveira Santos, Miguel; Domingues, Sara; Gromicho, Marta; Pinto, Susana; de Carvalho, Mamede. "Impact of SARS-CoV-2 Infection Among Non-Invasive Ventilated ALS Patients". Journal of Neuromuscular Diseases 9 2 (2022): 257-259. http://dx.doi.org/10.3233/jnd-210733.
    10.3233/jnd-210733
  20. de Carvalho, Mamede; Fernandes, Sofia R.; Pereira, Mariana; Gromicho, Marta; Santos, Miguel Oliveira; Alves, Inês; Pinto, Susana; Swash, Michael. "Respiratory function tests in amyotrophic lateral sclerosis: The role of maximal voluntary ventilation". Journal of the Neurological Sciences 434 (2022): 120143. http://dx.doi.org/10.1016/j.jns.2022.120143.
    10.1016/j.jns.2022.120143
  21. Santos Silva, Cláudia; Oliveira Santos, Miguel; Gromicho, Marta; Pronto-Laborinho, Ana; Conceição, Isabel; de Carvalho, Mamede. "Motor neuron disease in three asymptomatic pVal50Met TTR gene carriers". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 23 7-8 (2022): 627-629. http://dx.doi.org/10.1080/21678421.2022.2029899.
    10.1080/21678421.2022.2029899
  22. Cláudia Santos Silva; Miguel Oliveira Santos; Marta Gromicho; Susana Pinto; Michael Swash; Mamede de Carvalho. "Electromyographic findings in primary lateral sclerosis during disease progression". Clinical Neurophysiology 132 12 (2021): 2996-3001. https://doi.org/10.1016/j.clinph.2021.08.022.
    10.1016/j.clinph.2021.08.022
  23. van Rheenen, Wouter; van der Spek, Rick A. A.; Bakker, Mark K.; van Vugt, Joke J. F. A.; Hop, Paul J.; Zwamborn, Ramona A. J.; de Klein, Niek; et al. "Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology". Nature Genetics 53 12 (2021): 1636-1648. http://dx.doi.org/10.1038/s41588-021-00973-1.
    10.1038/s41588-021-00973-1
  24. Marta Gromicho. "Corrigendum: ¿' Fibrinogen as a Predictor of Survival in Amyotrophic Lateral Sclerosis". Frontiers in Cardiovascular Medicine 8 (2021): https://doi.org/10.3389/fcvm.2021.715842.
    10.3389/fcvm.2021.800151
  25. Falcão de Campos, Catarina; Gromicho, Marta; Uysal, Hilmi; Grosskreutz, Julian; Kuzma-Kozakiewicz, Magdalena; Oliveira Santos, Miguel; Pinto, Susana; et al. "Delayed Diagnosis and Diagnostic Pathway of ALS Patients in Portugal: Where Can We Improve?". Frontiers in Neurology 12 (2021): http://dx.doi.org/10.3389/fneur.2021.761355.
    10.3389/fneur.2021.761355
  26. Philippe Corcia; Christian Lunetta; Philippe Couratier; Patrick Vourc'h; Marta Gromicho; Claude Desnuelle; Marie-Hélène Soriani; Susana Pinto; Mamede de Carvalho. "Reply to the letter from Gazulla et al.". European Journal of Neurology (2021): https://doi.org/10.1111/ene.15134.
    10.1111/ene.15134
  27. Morgadinho, João; Pronto-Laborinho, Ana Catarina; Conceição, Vasco A.; Gromicho, Marta; Pinto, Susana; Swash, Michael; de Carvalho, Mamede. "Plasma Creatinine Level Does Not Predict Respiratory Function in Amyotrophic Lateral Sclerosis". Journal of Neuromuscular Diseases 8 5 (2021): 795-799. http://dx.doi.org/10.3233/jnd-200583.
    10.3233/jnd-200583
  28. Ana Catarina Pronto-Laborinho; Catarina S. Lopes; Vasco A. Conceição; Marta Gromicho; Nuno C. Santos; Mamede de Carvalho; Filomena A. Carvalho. "¿' Fibrinogen as a Predictor of Survival in Amyotrophic Lateral Sclerosis". Frontiers in Cardiovascular Medicine 8 (2021): http://dx.doi.org/10.3389/fcvm.2021.715842.
    10.3389/fcvm.2021.715842
  29. Marta Gromicho; Magdalena Kuzma-Kozakiewicz; Katarzyna Szacka; Krzysztof Nieporecki; Peter M. Andersen; Julian Grosskreutz; Susanne Petri; et al. "Motor neuron disease beginning with frontotemporal dementia: clinical features and progression". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration (2021): https://doi.org/10.1080/21678421.2021.1910309.
    10.1080/21678421.2021.1910309
  30. Júlia Costa; Marta Gromicho; Ana Pronto-Laborinho; Conceição Almeida; Ricardo A. Gomes; Ana C. L. Guerreiro; Abel Oliva; Susana Pinto; Mamede de Carvalho. "Cerebrospinal Fluid Chitinases as Biomarkers for Amyotrophic Lateral Sclerosis". Diagnostics 11 7 (2021): 1210-1210. https://doi.org/10.3390/diagnostics11071210.
    10.3390/diagnostics11071210
  31. Philippe Corcia; Christian Lunetta; Philippe Couratier; Patrick Vourc’h; Marta Gromicho; Claude Desnuelle; Marie-Hélène Soriani; Susana Pinto; Mamede de Carvalho. "Familial clustering of PLS and ALS: A supplementary evidence for a continuum". European Journal of Neurology (2021): https://doi.org/10.1111/ene.14960.
    10.1111/ene.14960
  32. Miguel Oliveira Santos; Isabel Castro; José Castro; Marta Gromicho; Mamede de Carvalho. "Assessment of sympathetic sudomotor function in amyotrophic lateral sclerosis with electrochemical skin conductance". Clinical Neurophysiology (2021): https://doi.org/10.1016/j.clinph.2021.05.016.
    10.1016/j.clinph.2021.05.016
  33. Leão, Tiago; Madeira, Sara C.; Gromicho, Marta; de Carvalho, Mamede; Carvalho, Alexandra M.. "Learning dynamic Bayesian networks from time-dependent and time-independent data: Unraveling disease progression in Amyotrophic Lateral Sclerosis". Journal of Biomedical Informatics 117 (2021): 103730. http://dx.doi.org/10.1016/j.jbi.2021.103730.
    10.1016/j.jbi.2021.103730
  34. Pereira, Mariana; Gromicho, Marta; Henriques, Ana; Pronto-Laborinho, Ana Catarina; Grosskreutz, Julian; Kuzma-Kozakiewicz, Magdalena; Petri, Susanne; et al. "Cardiovascular comorbidities in amyotrophic lateral sclerosis". Journal of the Neurological Sciences 421 (2021): 117292. http://dx.doi.org/10.1016/j.jns.2020.117292.
  35. Müller, Marcel; Gromicho, Marta; de Carvalho, Mamede; Madeira, Sara C.. "Explainable models of disease progression in ALS: Learning from longitudinal clinical data with recurrent neural networks and deep model explanation". Computer Methods and Programs in Biomedicine Update 1 (2021): 100018. http://dx.doi.org/10.1016/j.cmpbup.2021.100018.
    10.1016/j.cmpbup.2021.100018
  36. Mamede deCarvalho; Marta Gromicho; Peter Andersen; Julian Grosskreutz; Magdalena Kuzma-Kozakiewicz; Susanne Petri; Hilmi Uysal; Susana Pinto. "Peripheral neuropathy in ALS: phenotype association". Journal of Neurology, Neurosurgery & Psychiatry (2020): https://doi.org/10.1136/jnnp-2020-325164.
    10.1136/jnnp-2020-325164
  37. Uysal, HIlmi; Bilge, Ugur; Ilhanli, Nevruz; Gromicho, Marta; Grosskreutz, Julian; Kuzma-Kozakiewicz, Magdalena; Pinto, Susana; et al. "ALS and fertility: does ALS affect number of children patients have?". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 22 1-2 (2020): 94-100. http://dx.doi.org/10.1080/21678421.2020.1813313.
    10.1080/21678421.2020.1813313
  38. Schijven, Dick; Stevelink, Remi; McCormack, Mark; van Rheenen, Wouter; Luykx, Jurjen J.; Koeleman, Bobby P.C.; Veldink, Jan H.. "Analysis of shared common genetic risk between amyotrophic lateral sclerosis and epilepsy". Neurobiology of Aging 92 (2020): 153.e1-153.e5. http://dx.doi.org/10.1016/j.neurobiolaging.2020.04.011.
    10.1016/j.neurobiolaging.2020.04.011
  39. Oliveira Santos, Miguel; Gromicho, Marta; Pinto, Susana; De carvalho, Mamede. "Clinical characteristics in young-adult ALS – results from a Portuguese cohort study". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 21 7-8 (2020): 620-623. http://dx.doi.org/10.1080/21678421.2020.1790611.
    10.1080/21678421.2020.1790611
  40. Marta Gromicho; Ana Margarida Coutinho; Ana Catarina Pronto-Laborinho; Rita Raposeiro; Joana Tavares; Diana Antunes; Mamede de Carvalho. "Targeted next-generation sequencing study in familial ALS-FTD Portuguese patients negative for C9orf72 HRE". Journal of Neurology (2020): https://doi.org/10.1007/s00415-020-10042-y.
    10.1007/s00415-020-10042-y
  41. Henning, Franclo; Braga, Anna Caroline; Gromicho, Marta; Pinto, Susana; de Carvalho, Mamede. "Authors’ reply: Differences between South African and Portuguese ALS cohorts from an environmental perspective". Journal of the Neurological Sciences 414 (2020): 116932. http://dx.doi.org/10.1016/j.jns.2020.116932.
    10.1016/j.jns.2020.116932
  42. Braga, Anna Caroline; Gromicho, Marta; Pinto, Susana; de Carvalho, Mamede; Henning, Franclo. "A comparative study of South African and Portuguese amyotrophic lateral sclerosis cohorts". Journal of the Neurological Sciences 414 (2020): 116857. http://dx.doi.org/10.1016/j.jns.2020.116857.
  43. Gromicho, Marta; Figueiral, Manuel; Uysal, Hilmi; Grosskreutz, Julian; Kuzma-Kozakiewicz, Magdalena; Pinto, Susana; Petri, Susanne; et al. "Spreading in ALS: The relative impact of upper and lower motor neuron involvement". Annals of Clinical and Translational Neurology 7 7 (2020): 1181-1192. http://dx.doi.org/10.1002/acn3.51098.
    10.1002/acn3.51098
  44. Duque, Tatiana; Gromicho, Marta; Pronto-Laborinho, Ana Catarina; de Carvalho, Mamede. "Transforming growth factor-ß plasma levels and its role in amyotrophic lateral sclerosis". Medical Hypotheses 139 (2020): 109632. http://dx.doi.org/10.1016/j.mehy.2020.109632.
    10.1016/j.mehy.2020.109632
  45. Kuraszkiewicz, B.; Goszczynska, H.; Podsiadly-Marczykowska, T.; Piotrkiewicz, M.; Andersen, P.; Gromicho, M.; Grosskreutz, J.; et al. "Potential Preventive Strategies for Amyotrophic Lateral Sclerosis". Frontiers in Neuroscience 14 (2020): http://dx.doi.org/10.3389/fnins.2020.00428.
    10.3389/fnins.2020.00428
  46. Torrieri, Maria Claudia; Miranda, Bruno; Gromicho, Marta; Pinto, Susana; de Carvalho, Mamede. "Reliability of phrenic nerve conduction study: In healthy controls and in patients with primary lateral sclerosis". Clinical Neurophysiology 131 5 (2020): 994-999. http://dx.doi.org/10.1016/j.clinph.2020.02.010.
    10.1016/j.clinph.2020.02.010
  47. Diekmann, Kristin; Kuzma-Kozakiewicz, Magdalena; Piotrkiewicz, Maria; Gromicho, Marta; Grosskreutz, Julian; Andersen, Peter M.; de Carvalho, Mamede; et al. "Impact of comorbidities and co-medication on disease onset and progression in a large German ALS patient group". Journal of Neurology 267 7 (2020): 2130-2141. http://dx.doi.org/10.1007/s00415-020-09799-z.
    10.1007/s00415-020-09799-z
  48. Bruno Miranda; Marta Gromicho; Mariana Pereira; Susana Pinto; Michael Swash; Mamede de Carvalho. "Diaphragmatic CMAP amplitude from phrenic nerve stimulation predicts functional decline in ALS". Journal of Neurology (2020): https://doi.org/10.1007/s00415-020-09818-z.
    10.1007/s00415-020-09818-z
  49. Silva, Daniela Pimenta; Soeiro E Sá, Mariana; Silveira, Fernando; Pinto, Susana; Gromicho, Marta; Sousa, Ana Berta; Leão, Miguel; De Carvalho, Mamede. "VRK1 variants in two Portuguese unrelated patients with childhood-onset motor neuron disease". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 21 3-4 (2020): 291-295. http://dx.doi.org/10.1080/21678421.2020.1746343.
    10.1080/21678421.2020.1746343
  50. Costa, Júlia; Pronto-Laborinho, Ana; Pinto, Susana; Gromicho, Marta; Bonucci, Sara; Tranfield, Erin; Correia, Catarina; et al. "Investigating LGALS3BP/90¿K glycoprotein in the cerebrospinal fluid of patients with neurological diseases". Scientific Reports 10 1 (2020): http://dx.doi.org/10.1038/s41598-020-62592-w.
    10.1038/s41598-020-62592-w
  51. Campos, Catarina Falcão; Gromicho, Marta; Uysal, Hilmi; Grosskreutz, Julian; Kuzma-Kozakiewicz, Magdalena; Pinto, Susana; Petri, Susanne; de Carvalho, Mamede. "Family history of neurodegenerative disorders in patients with amyotrophic lateral sclerosis: population-based case–control study". Journal of Neurology, Neurosurgery & Psychiatry 91 6 (2020): 671-672. http://dx.doi.org/10.1136/jnnp-2019-322561.
  52. Barc, Krzysztof; Szacka, Katarzyna; Nieporecki, Krzysztof; de Carvalho, Mamede; Gromicho, Marta; Grosskreutz, Julian; Petri, Susanne; et al. "Emotional Lability at Disease Onset Is an Independent Prognostic Factor of Faster Disease Progression in Amyotrophic Lateral Sclerosis". Aging and disease 11 5 (2020): 1021. http://dx.doi.org/10.14336/ad.2019.1120.
    Acesso aberto • 10.14336/ad.2019.1120
  53. Tazelaar, Gijs H P; Boeynaems, Steven; De Decker, Mathias; van Vugt, Joke J F A; Kool, Lindy; Goedee, H Stephan; McLaughlin, Russell L; et al. "ATXN1 repeat expansions confer risk for amyotrophic lateral sclerosis and contribute to TDP-43 mislocalization". Brain Communications 2 2 (2020): http://dx.doi.org/10.1093/braincomms/fcaa064.
    10.1093/braincomms/fcaa064
  54. Pinto, Susana; Gromicho, Marta; Swash, Michael; deCarvalho, Mamede. "Cervical muscle weakness is a marker of respiratory dysfunction in amyotrophic lateral sclerosis". Journal of Neurology, Neurosurgery & Psychiatry 91 3 (2019): 323-324. http://dx.doi.org/10.1136/jnnp-2019-321077.
    10.1136/jnnp-2019-321077
  55. Costa, M.R.; Gromicho, M.; Pronto-Laborinho, A.C.; Miltenberger Miltényi, G.; de Carvalho, M.. "Novel TBK1 LoF variant in a family with upper motor neuron predominant motor neuron disease". Journal of the Neurological Sciences 403 (2019): 117-118. http://dx.doi.org/10.1016/j.jns.2019.06.029.
    10.1016/j.jns.2019.06.029
  56. Pinto, Susana; Gromicho, Marta; de Carvalho, Mamede. "Assessing upper limb function with ALSFRS-R in amyotrophic lateral sclerosis patients". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20 5-6 (2019): 445-448. http://dx.doi.org/10.1080/21678421.2019.1606243.
    10.1080/21678421.2019.1606243
  57. Pronto-Laborinho A; Pinto S; Gromicho M; Pereira M; Swash M; de Carvalho M. "Interleukin-6 and amyotrophic lateral sclerosis.". Journal of the neurological sciences (2019): http://europepmc.org/abstract/med/30682521.
    10.1016/j.jns.2019.01.026
  58. Korner, Sonja; Kammeyer, Johanna; Zapf, Antonia; Kuzma-Kozakiewicz, Magdalena; Piotrkiewicz, Maria; Kuraszkiewicz, Bozenna; Goszczynska, Hanna; et al. "Influence of Environment and Lifestyle on Incidence and Progress of Amyotrophic Lateral Sclerosis in A German ALS Population". Aging and disease 10 2 (2019): 205. http://dx.doi.org/10.14336/ad.2018.0327.
    10.14336/ad.2018.0327
  59. Marta Gromicho; Susana Pinto; Eugeniu Gisca; Ana Catarina Pronto-Laborinho; Peter M. Andersen; Mamede de Carvalho. "Frequency of C9orf72 hexanucleotide repeat expansion and SOD1 mutations in Portuguese patients with amyotrophic lateral sclerosis". Neurobiology of Aging 70 (2018): 325.e7-325.e15. https://doi.org/10.1016/j.neurobiolaging.2018.05.009.
    10.1016/j.neurobiolaging.2018.05.009
  60. Santos MO; Gromicho M; Pinto S; de Carvalho M. "Very late-onset amyotrophic lateral sclerosis in a Portuguese cohort.". Amyotrophic lateral sclerosis & frontotemporal degeneration (2018): http://europepmc.org/abstract/med/30265147.
    10.1080/21678421.2018.1510010
  61. Miltenberger-Miltenyi G; Conceição VA; Gromicho M; Pronto-Laborinho AC; Pinto S; Andersen PM; de Carvalho M. "C9orf72 expansion is associated with accelerated decline of respiratory function and decreased survival in amyotrophic lateral sclerosis.". Journal of neurology, neurosurgery, and psychiatry (2018): http://europepmc.org/abstract/med/29661924.
    10.1136/jnnp-2018-318032
  62. Westeneng HJ; Debray TPA; Visser AE; van Eijk RPA; Rooney JPK; Calvo A; Martin S; et al. "Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model.". The Lancet. Neurology (2018): http://europepmc.org/abstract/med/29598923.
    10.1016/s1474-4422(18)30089-9
  63. Pronto Laborinho, A. C.; Gromicho, M.; Pereira, M.; Lopes, C.; Santos, N.; Carvalho, F.; de Carvalho, M.. "Molecular biomarkers associated with respiratory insufficiency in Amyotrophic Lateral Sclerosis". European Journal of Neurology (2018): https://publons.com/wos-op/publon/14365246/.
  64. Marta Gromicho. "Theme 1 Genetics and genomics". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 18 sup2 (2017): 78-101. http://dx.doi.org/10.1080/21678421.2017.1371515.
    10.1080/21678421.2017.1371515
  65. Pronto-Laborinho, A. C.; Gromicho, M.; Pereira, M.; Pinto, S.; Barros, M. do A.; Swash, M.; Carvalho, M.. "Plasma level of club-cell ( CC -16) predicts outcome in amyotrophic lateral sclerosis". Acta Neurologica Scandinavica 137 2 (2017): 233-237. http://dx.doi.org/10.1111/ane.12851.
    10.1111/ane.12851
  66. Oliveira Santos, Miguel; Caldeira, Inês; Gromicho, Marta; Pronto-Laborinho, Ana; de Carvalho, Mamede. "Brain white matter demyelinating lesions and amyotrophic lateral sclerosis in a patient with C9orf72 hexanucleotide repeat expansion". Multiple Sclerosis and Related Disorders 17 (2017): 1-4. http://dx.doi.org/10.1016/j.msard.2017.06.010.
    10.1016/j.msard.2017.06.010
  67. De Carvalho, Mamede; Ryczkowski, Adam; Andersen, Peter; Gromicho, Marta; Grosskreutz, Julian; Kuzma-Kozakiewicz, Magdalena; Petri, Susanne; Piotrkiewicz, Maria; Miltenberger Miltenyi, Gabriel. "International Survey of ALS Experts about Critical Questions for Assessing Patients with ALS". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 18 7-8 (2017): 505-510. http://dx.doi.org/10.1080/21678421.2017.1349150.
    10.1080/21678421.2017.1349150
  68. Gromicho, Marta; Oliveira Santos, Miguel; Pinto, Anabela; Pronto-Laborinho, Ana; De Carvalho, Mamede. "Young-onset rapidly progressive ALS associated with heterozygous FUS mutation". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 18 5-6 (2017): 451-453. http://dx.doi.org/10.1080/21678421.2017.1299762.
    10.1080/21678421.2017.1299762
  69. Pinto, Susana; Gromicho, Marta; de Carvalho, Mamede. "Sialorrhoea and reversals in ALS functional rating scale". Journal of Neurology, Neurosurgery & Psychiatry 88 2 (2016): 187-188. http://dx.doi.org/10.1136/jnnp-2016-313614.
    10.1136/jnnp-2016-313614
  70. Gonçalves, Margarida; De Carvalho, Mamede; Peixoto, Cristina; Alves, Paula; Barreto, Carmo; Oliva, Abel; Pinto, Susana; et al. "Phosphoneurofilament heavy chain and vascular endothelial growth factor as cerebrospinal fluid biomarkers for ALS". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 18 1-2 (2016): 134-136. http://dx.doi.org/10.1080/21678421.2016.1212894.
    10.1080/21678421.2016.1212894
  71. Gromicho, M.; Magalhães, M.; Torres, F.; Dinis, J.; Fernandes, A.R.; Rendeiro, P.; Tavares, P.; et al. "Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib". Oncology Reports 29 2 (2013): 741-750. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872768729&partnerID=MN8TOARS.
    10.3892/or.2012.2153
  72. Dinis, J.; Silva, V.; Gromicho, M.; Martins, C.; Laires, A.; Tavares, P.; Rendeiro, P.; et al. "DNA damage response in imatinib resistant chronic myeloid leukemia K562 cells". Leukemia and Lymphoma 53 10 (2012): 2004-2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865767542&partnerID=MN8TOARS.
    10.3109/10428194.2012.681654
  73. Rodrigues, A.S.; Dinis, J.; Gromicho, M.; Martins, C.; Laires, A.; Rueff, J.. "Genomics and cancer drug resistance". Current Pharmaceutical Biotechnology 13 5 (2012): 651-673. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860265107&partnerID=MN8TOARS.
    10.2174/138920112799857549
  74. Gromicho, M.; Dinis, J.; Magalhães, M.; Fernandes, A.R.; Tavares, P.; Laires, A.; Rueff, J.; Rodrigues, A.S.. "Development of imatinib and dasatinib resistance: Dynamics of expression of drug transporters ABCB1, ABCC1, ABCG2, MVP, and SLC22A1". Leukemia and Lymphoma 52 10 (2011): 1980-1990. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053211502&partnerID=MN8TOARS.
    10.3109/10428194.2011.584005
  75. Dinis, R.; Gromicho, L.; Martins, S.; Laires, L.; Rueff, A.; Rodrigues, S.. "EVALUATION OF DSBS REPAIR IN IMATINIB RESISTANT CELL LINES". Haematologica (2009): https://publons.com/wos-op/publon/9076275/.
  76. Gromicho, L.; Dinis, J.; Martins, C.; Laires, A.; Rueff, J.; Rodrigues, A.. "ROLE OF ABC TRANSPORTERS IN THE DEVELOPMENT OF IMATINIB RESISTANCE". Haematologica (2009): https://publons.com/wos-op/publon/6803649/.
  77. Gromicho, M.; Coutanceau, J.-P.; Ozouf-Costaz, C.; Collares-Pereira, M.J.. "Contrast between extensive variation of 28S rDNA and stability of 5S rDNA and telomeric repeats in the diploid-polyploid Squalius alburnoides complex and in its maternal ancestor Squalius pyrenaicus (Teleostei, Cyprinidae)". Chromosome Research 14 3 (2006): 297-306. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646060426&partnerID=MN8TOARS.
    10.1007/s10577-006-1047-4
  78. Gromicho, M.; Coelho, M.M.; Alves, M.J.; Collares-Pereira, M.J.. "Cytogenetic analysis of Anaecypris hispanica and its relationship with the paternal ancestor of the diploid-polyploid Squalius alburnoides complex". Genome 49 12 (2006): 1621-1627. http://www.scopus.com/inward/record.url?eid=2-s2.0-34249680658&partnerID=MN8TOARS.
    10.1139/G06-121
  79. Gromicho, M.; Ozouf-Costaz, C.; Collares-Pereira, M.J.. "Lack of correspondence between CMA3-, Ag-positive signals and 28S rDNA loci in two Iberian minnows (Teleostei, Cyprinidae) evidenced by sequential banding". Cytogenetic and Genome Research 109 4 (2005): 507-511. http://www.scopus.com/inward/record.url?eid=2-s2.0-20944445798&partnerID=MN8TOARS.
    10.1159/000084211
  80. Gromicho, M.; Collares-Pereira, M.J.. "Polymorphism of major ribosomal gene chromosomal sites (NOR-phenotypes) in the hybridogenetic fish Squalius alburnoides complex (Cyprinidae) assessed through crossing experiments". Genetica 122 3 (2004): 291-302. http://www.scopus.com/inward/record.url?eid=2-s2.0-8544275345&partnerID=MN8TOARS.
    10.1007/s10709-004-1420-1
  81. Gromicho, M; Ozouf-Costaz, C; Collares-Pereira, MJ. "Molecular versus classical cytogenetic data on the Squalius alburnoides complex (Teleostei, Cyprinidae): What is new?". Cytogenetic and Genome Research 106 1 (2004): 16-16. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000224243600032&KeyUID=WOS:000224243600032.
    10.1159/000078555
  82. Marta Gromicho. "Simultaneous production of triploid and haploid eggs by triploid Squalius alburnoides (Teleostei: Cyprinidae)". Journal of Experimental Zoology Part A: Comparative Experimental Biology 301 7 (2004): 552-558. http://www.scopus.com/inward/record.url?eid=2-s2.0-3442892990&partnerID=MN8TOARS.
    10.1002/jez.a.51
Capítulo de livro
  1. André Ferreira; Sara C. Madeira; Marta Gromicho; Mamede de Carvalho; Susana Vinga; Alexandra M. Carvalho. "Predictive Medicine Using Interpretable Recurrent Neural Networks". 2021.
    10.1007/978-3-030-68763-2_14
  2. Sofia Pires; Marta Gromicho; Susana Pinto; Mamede de Carvalho; Sara C. Madeira. "Patient Stratification Using Clinical and Patient Profiles: Targeting Personalized Prognostic Prediction in ALS". 2020.
    10.1007/978-3-030-45385-5_47
  3. Joana Matos; Sofia Pires; Helena Aidos; Marta Gromicho; Susana Pinto; Mamede de Carvalho; Sara C. Madeira. "Unravelling Disease Presentation Patterns in ALS Using Biclustering for Discriminative Meta-Features Discovery". 2020.
    10.1007/978-3-030-45385-5_46
  4. Soares, Diogo; Henriques, Rui; Gromicho, Marta; Pinto, Susana; de Carvalho, Mamede; Madeira, Sara C.. "Towards Triclustering-Based Classification of Three-Way Clinical Data: A Case Study on Predicting Non-invasive Ventilation in ALS". In Practical Applications of Computational Biology & Bioinformatics, 14th International Conference (PACBB 2020), 112-122. Springer International Publishing, 2020.
    10.1007/978-3-030-54568-0_12
  5. Gromicho, Marta; Rueff, José; Rodrigues, António Sebastião. "Dynamics of Expression of Drug Transporters: Methods for Appraisal". In Methods in Molecular Biology, 75-85. Springer New York, 2016.
    10.1007/978-1-4939-3347-1_6
  6. S., Antnio; Costa, Bruno; Martins, Clia; Gromicho, Marta; G., Nuno; S., Patrcia; Rueff, Jos. "DNA Repair and Resistance to Cancer Therapy". In New Research Directions in DNA Repair. InTech, 2013.
    10.5772/53952
  7. Marta Gromicho. "The evolutionary role of hybridization in an Iberian cyprinid fish – A cytogenetic review, pp. 41-67. In: Fish Cytogenetics, Eds: E. Pisano, C. Ozouf-Costaz, F. Foresti & B. G. Kapoor, Science Publisher, Inc., USA.". 2006.
    10.1201/b10746-3
Poster em conferência
  1. Marta Gromicho. "Delayed diagnosis and diagnostic pathway of ALS patients: where can we improve?". Trabalho apresentado em ENCALS meeting 2021, 2021.
  2. Marta Gromicho. "Electromyographic findings in primary lateral sclerosis: a longitudinal study". Trabalho apresentado em ENCALS meeting 2021, 2021.
  3. Marta Gromicho. "Gamma Prime fibrinogen as a predictor of survival in Amyotrophic Lateral Sclerosis". Trabalho apresentado em ENCALS meeting 2021, 2021.
  4. Marta Gromicho. "COVID-19 pandemic impact on the respiratory function of ALS patients at first visit". Trabalho apresentado em ENCALS meeting 2021, 2021.
  5. Marta Gromicho. "Dynamic Bayesian networks for stratification of disease progression in ALS". Trabalho apresentado em ENCALS meeting 2021, 2021.
  6. Marta Gromicho. "Comparative study of CSF chitinases in ALS: correlation with clinical features". Trabalho apresentado em ENCALS meeting 2021, 2021.
  7. Marta Gromicho. "Comparison of individual disease courses in partner centers of the ONWebDUALS project applying the D50 model". Trabalho apresentado em 31st International Symposium on ALS/MND, 2020.
  8. Marta Gromicho. "Gamma fibrinogen as a predictor of survival in Amyotrophic Lateral Sclerosis". Trabalho apresentado em 31st International Symposium on ALS/MND, 2020.
  9. Marta Gromicho; Campos, Catarina Falcão; Gromicho, Marta; Uysal, Hilmi; Grosskreutz, Julian; Kuzma-Kozakiewicz, Magdalena; Pinto, Susana; Petri, Susanne; de Carvalho, Mamede. "Assessment of microRNAs as biomarkers of disease progression in Amyotrophic Lateral Sclerosis". Trabalho apresentado em 31st International Symposium on ALS/MND, 2020.
    10.1080/21678421.2020.1790611
  10. Marta Gromicho. "Significant events during ALS progression according to the D50 model in the ONWebDUALS cohort". 2019.
    https://doi.org/10.1080/21678421.2019.1646998
  11. Marta Gromicho. "Emotional lability at disease onset is a prognostic factor of faster disease progression in amyotrophic lateral sclerosis.". Trabalho apresentado em ENCALS meeting 2019, 2019.
  12. Marta Gromicho. "The D50 Progression Model for Amyotrophic Lateral Sclerosis: Extension to and Validation in Global Cohorts". Trabalho apresentado em ENCALS meeting 2019, 2019.
  13. Marta Gromicho. "Club-cell protein (CC-16): prognostic biomarker in ALS". 2018.
    10.1080/21678421.2018.1510582
  14. Marta Gromicho. "C9orf72 expansion is associated with accelerated decline of respiratory function and decreased survival in amyotrophic lateral sclerosis". 2018.
    10.1080/21678421.2018.1510572
  15. Marta Gromicho. "The world according to the D50 model of ALS progression". 2018.
    10.1080/21678421.2019.1646998
  16. Marta Gromicho. "ALS with FTD-onset: features and progression pattern". 2018.
    10.1080/21678421.2018.1510580
  17. Marta Gromicho. "Genetic profile of ALS patients in Portugal". 2018.
    10.1080/21678421.2018.1510210
  18. Marta Gromicho. "Peripheral neuropathy in ALS: prevalence and risk factors". 2018.
    10.1080/21678421.2018.1510575
  19. Marta Gromicho. "Fibrinogen and changes in morphology of erythrocytes in amyotrophic lateral sclerosis". 2018.
    10.1080/21678421.2018.1510571
Resumo em conferência
  1. Marta Gromicho. "ALS onset in old people: clinical features and prognosis". 2018.
    10.1080/21678421.2018.1510202
  2. Marta Gromicho. "Methylation status of selected microRNAs in imatinib-sensitive and imatinib-resistant chronic myeloid leukaemia (K562) cell lines". 2013.
    10.1016/S0959-8049(13)70060-1
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/11/10 Expanding the genotype-phenotype diversity of amyotrophic lateral sclerosis. Congresso Português de Neurologia
(Porto, Portugal)
2023/11 1. Perfil fenotípico da doença de neurónio motor associada à expansão do gene c9orf72 em Portugal.Cláudia Santos Silva; Marta Gromicho; Sara Simão; Ana C Pronto-Laborinho; Inês Alves; Susana Pinto; Miguel Oliveira Santos, MDe Carvalho 2. Preditores de sobrevida na fase final da doença esclerose lateral amiotrófica Maria Fortuna Baptista; Marta Gromicho; Miguel Oliveira Santos, Mamede De Carvalho. 3. Red cell distribution width (rdw) in ALS. Ana Laborinho ; CS Lopes ; V Conceição ; Marta Gromicho ; DM Lopes ; NC Santos; F Carvalho; MDe Carvalho Congresso Português de Neurologia
(Porto, Portugal)
2022/12/06 Presentations: 1. The flail-arm syndrome: the influence of phenotypic features 2. Blood neutrophil-to-lymphocyte ratio predicts survival in ALS patients 3. Erythrocyte membrane properties in patients with ALS 4. Relevance of respiratory tests in determining respiratory involvement in ALS 5. The role of maximal voluntary ventilation in evaluating the respiratory function of ALS patients 6. Trends in the diagnostic delay and pathway for ALS patients across different countries 33rd International Symposium on ALS/MND.
2022/11/17 1. Clinical characteristics in amyotrophic lateral sclerosis with Sub-Saharan Africa ancestry a Portuguese hospital-based cohort study 2. Sinais piramidais na esclerose lateral primária 3. Wasted Leg Syndrome: uma forma benigna e rara de doença do neurónio motor com envolvimento de membros inferiores Congresso Nacional de Neurologia
(Aveiro, Portugal)
2022/06/25 Wasted Leg Syndrome: an atypical slow-progressive form of lower motor neuron disease 8th Congress of the European Academy of Neurology, June 25-28, 2022 in Vienna, Austria.
(Vienna, Áustria)
2022/06/20 Evaluation of morphological and elastic changes on erythrocytes and ¿’ fibrinogen as possible predictors of survival in Amyotrophic Lateral Sclerosis 8th International Iberian Biophysics congress, 20th-21st June 2022, Bilbao, Spain
(Bilbao, Espanha)
2021/12 1. Amyotrophic lateral sclerosis in three asymptomatic Val50Met TTR gene carriers 2. Thyroid disease in Portuguese amyotrophic lateral sclerosis patients: a case-control study 3. Spreading pattern in ALS patients with respiratory onset 4. Clinical characteristics of a large motor neuron disease cohort in Portugal: exploring differences from 1994 to 2020 5. Red cell distribution width (RDW) in ALS 6. Delayed diagnosis and diagnostic pathway of ALS patients in Portugal: where can we improve? 7. Is dysphagia a predictive factor for ALS survival 32nd INTERNATIONAL SYMPOSIUM on ALS/MND. 07 -10 December 2021: online
2021/05/12 1. Gamma Prime fibrinogen as a predictor of survival in Amyotrophic Lateral Sclerosis 2. COVID-19 pandemic impact on the respiratory function of ALS patients at first visit 3. Dynamic Bayesian networks for stratification of disease progression in ALS 4. Delayed diagnosis and diagnostic pathway of ALS patients: where can we improve? 5. Comparative study of CSF chitinases in ALS: correlation with clinical features 6. Electromyographic findings in primary lateral sclerosis: a longitudinal study ENCALS meeting 2021
2020/12/09 1. Cardiovascular comorbidities in Amyotrophic Lateral Sclerosis 2. Clinical characteristics in young-adult ALS – results from a Portuguese cohort study 3. Family history of neurodegenerative disorders in patients with amyotrophic lateral sclerosis: a population-based case-control study 4. Gamma fibrinogen as a predictor of survival in Amyotrophic Lateral Sclerosis 5. A comparative study of South African and Portuguese amyotrophic lateral sclerosis cohorts 6. Assessment of microRNAs as biomarkers of disease progression in ALS 31st International Symposium on ALS/MND
2019/12/04 Significant events during ALS progression according to the D50 model in the ONWebDUALS cohort 30th International Symposium on ALS/MND 2019
(Perth, Austrália)
2019/05/15 1. Emotional lability at disease onset is a prognostic factor of faster disease progression in amyotrophic lateral sclerosis. 2. The D50 Progression Model for Amyotrophic Lateral Sclerosis: Extension to and Validation in Global Cohorts ENCALS meeting 2019
(Tours, França)
2018/12/09 ALS Onset in Old People: clinical features and prognosis. Oliveira Santos, M; Gromicho, M; Pinto, M; de Carvalho, M. 29th INTERNATIONAL SYMPOSIUM on ALS/MND. Glasgow. December 2018 29th INTERNATIONAL SYMPOSIUM on ALS/MND
(Glasgow, Reino Unido)
2018/12/08 ONWebDUALS Consortium: Spreading in ALS. Gromicho, M; Pinto, S; Figueiral, M; Madeira, SC; Andersen, PM; Grosskreutz, J; Kuzma-Kozakiewicz, M; Petri, S; Szacka, K; Stubendorff, B; Uysal, H; Swash, M; de Carvalho, M. ENCALS SATELLITE MEETING. Glasgow. December 2018 ENCALS SATELLITE MEETING
(Glasgow, Reino Unido)
2018/12/08 Validation of the D50 Model of ALS Progression in Representative Cohorts from Europe and the USA. Gaur, N; Stubendorff, B; Grehl, T; Moisse, M; van Damme, P; Neuwirth, C; Weber, M; Manera, U; Chio, A; Veldink, J; van den Berg, L; Meyer, T; Koritnik, B; Zidar, J; Wicks, P; Corcia, P; Couratier, P; Gromicho, M; de Carvalho, M; Szacka, K; Kuzma-Kozakiewicz, M; Fartmann, F: Petri, P; Uysal, H; Grosskreutz, J. 29th INTERNATIONAL SYMPOSIUM on ALS/MND. Glasgow. December 201 29th INTERNATIONAL SYMPOSIUM on ALS/MND
(Glasgow, Reino Unido)
2018/12/07 1. Club-cell protein (CC-16): prognostic biomarker in ALS 2. The impact of hand dominance in the ALSFRS-R scoring 3. A diagnostic pathway in patients with amyotrophic lateral sclerosis 4. ALS onset in old people: clinical features and prognosis 5. ALS with FTD-onset: features and progression pattern 6. Regional spreading of bulbar-onset ALS patients: implications of UMN vs LMN 7. Phenotypes 8. Peripheral neuropathy in ALS: prevalence and risk factors 9. Genetic profile of ALS patients in Portugal 29th INTERNATIONAL SYMPOSIUM on ALS/MND
(Glasgow, Reino Unido)
2018/12/07 10. C9orf72 expansion is associated with the accelerated decline of respiratory function and decreased survival in amyotrophic lateral sclerosis 11. Fibrinogen and changes in the morphology of erythrocytes in amyotrophic lateral sclerosis 12. The world according to the D50 model of ALS progression 13. Enhancing the comparability of individual disease courses in partner centers of the ONWebDUALS project using the D50 progression model 14. Factors influencing diagnosis delay in amyotrophic lateral sclerosis 29th INTERNATIONAL SYMPOSIUM on ALS/MND
(Glasgow, Reino Unido)
2018/06/16 Molecular biomarkers associated with respiratory insufficiency in Amyotrophic Lateral Sclerosis 4th Congress of the European Academy of Neurology, 2018, Lisbon, Portugal.
(Lisbon, Portugal)
2018/02/01 Biomarcadores Respiratórios na Abordagem Clínica da Esclerose Lateral Amiotrófica. Pronto-Laborinho, A; Gromicho, M; Pereira, M; Pinto, S; Barros, MA; Swash, M; de Carvalho, M. XXV CONGRESSO de PNEUMOLOGIA do NORTE. Oporto, Feb 2018 XXV CONGRESSO de PNEUMOLOGIA do NORTE
(Porto, Portugal)
2017/11/16 Biomarcadores Respiratórios na Abordagem Clínica da Esclerose Lateral Amiotrófica. Pronto-Laborinho AC, Gromicho M, Pereira M, Lopes CS, Santos NC, Carvalho FA, de Carvalho M. Congresso de Neurologia de 2017 - Alterações Climáticas, Globalização, Ambiente e Neurologia, 15 – 18 November 2017, Lisbon.
2017/11/16 International Survey of ALS Experts about Critical Questions for Assessing Patients with ALS. Miltenyi GM, Ryczkowski A, Andersen P, Gromicho M, Grosskreutz J, Kuzma-Kozakiewicz M, Petri S, Piotrkiewicz M & De Carvalho M. Congresso de Neurologia de 2017 - Alterações Climáticas, Globalização, Ambiente e Neurologia, 15 – 18 November 2017, Lisbon.
2016/12/06 Development and External Validation of a Prognostic Model Estimating Survival in Individual ALS Patients. Westeneng H-J, Debray T, Visser A, Walhout R, Van Rheenen W, Seelen M, Van Eijk R, Dekker AM, et al. 27th International Symposium on ALS/MND. Dublin, Ireland, 7-9 December 2016. 27th International Symposium on ALS/MND
2015/05/29 Do virtual para a natureza: estratégias de comunicação do projecto BioDiversity4All. Gromicho M, Tiago P, Ribeiro F, Ferreira LT, & Dix M. SciCom Pt 2015 – Congresso de Comunicação de Ciência. Lagos, 28-30 May 2015.
2015/04/28 From North to South, from East to West: National and cultural differences of Citizen Science in Europe. A Portuguese case-study. Tiago P, Ferreira LT, Gromicho M & Ribeiro F. Workshop Citizen Science and its science-policy impact – a comparison of International science systems. iDiv- Leipzig, 27-29 Apr 2015.
2013/10/23 BioDiversity4All Project - Connecting people in the Web 2.0 to increase biodiversity knowledge. Tiago P, Ribeiro F, Ferreira LT, Gromicho M & Dix M. European Citizen Science Association Autumn Citizen Science Workshop. Brussels, 22 - 23 Out 2013.
2013/02/18 Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia. Gromicho M. Seminários CIGMH, IHMT, Lisbon, 18 Feb 2013. Seminários CIGMH
(Lisboa, Portugal)
2011/11/11 mRNA expression of drug transporters over time in Chronic Myeloid Leukemia patients sensitive and resistant to Imatinib Gromicho M, Magalhães M, Torres F, Dinis J, Fernandes AR, Rendeiro P, Tavares P, Laires A, Rueff J, Rodrigues AS. 15ª Reunião Anual da Sociedade Portuguesa de Genética Humana, Lisbon, 10-12 November 2011. Reunião Anual da Sociedade Portuguesa de Genética Humana
(Lisboa, Portugal)
2010/09/27 BioDiversity4All Project - Connecting People in the Web 2.0 to increase Biodiversity knowledge. Tiago P, Ribeiro F, Ferreira LT, Gromicho M & Dix M. VESTA-GIS Workshop (Vocational Education and Sectoral Training network on GIS & GI application domains), Instituto Geográfico Português, Lisbon, 27-29 Sep 2010.
2010/07/12 BioDiversity4All Project. Tiago P, Ribeiro F, Ferreira LT, Gromicho M & Dix M. Meeting of GEO-BON (The Group on Earth Observations, Biodiversity Observation Network), Óbidos, 12 Jul 2010.
2006/06/20 Cytogenetic data on a model system of evolution-in-action by hybridization and polyploidy: the fish Squalius alburnoides complex. Gromicho M & Collares-Pereira MJ. 17th European Colloquium on Animal Cytogenetics and Gene Mapping, Lisbon, Portugal, 20th June 2006. European Colloquium on Animal Cytogenetics and Gene Mapping
(Lisboa, Portugal)
2006/03/10 Abordagem citogenética à poliploidização do genoma no complexo Squalius alburnoides, um case-study de evolução em acção. Gromicho M. Encontros de Scientia, Centro de Biologia Ambiental, FCUL, Lisbon, 10 March 2006. Encontros de Scientia, Centro de Biologia Ambiental, FCUL
(Lisboa, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2022/11 - Atual Exercício físico pré-mórbido e declínio da função respiratória em Esclerose Lateral Amiotrófica
Coorientador
 Medicina (Mestrado)
Universidade de Lisboa Faculdade de Medicina, Portugal
2022/10 - Atual Creatine Kinase and respiratory decline in Amyotrophic Lateral Sclerosis: friend or foe?
Coorientador
 Medicina (Mestrado)
Universidade de Lisboa Faculdade de Medicina, Portugal
2022/10 - Atual O Índice de Massa Corporal como fator preditor da progressão da Função Respiratória na Esclerose Lateral Amiotrófica
Coorientador
 Neurociências
Universidade de Lisboa Faculdade de Medicina, Portugal
2021/11 - 2022/09 Factores de risco cardiovasculares na Esclerose Lateral Amiotrófica
Coorientador
 Medicina (Mestrado)
Universidade de Lisboa Faculdade de Medicina, Portugal
2009/09/01 - 2010/09/01 O papel da biotransformação e do transporte celular na resistência ao Imatinib
Orientador
 Genética Molecular e Biomedicina (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2008/09/01 - 2009/06/30 Papel de proteínas transportadoras na resistência ao Imatinib e Dasatinib em Leucemia Mielóide Crónica
Coorientador
 Bioquímica (Licenciatura/Bacharelato)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2022/02/04 Investigating chitotriosidase and glycosyltransferase 8 domain-containing protein 1 in Amyotrophic Lateral Sclerosis
Arguente principal
 Maria Beatriz Ribeiro Felgueiras (Mestrado)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2021/04/08 Identification of microRNAs as biomarkers of therapy failure in Philadelphia Negative Myeloproliferative Neoplasms
Arguente principal
 Daniela Catarina de Castro Dias (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2013/09/01 - 2014/02/01 Princípios de Toxicologia Bioquímica para a Saúde (Mestrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2013/01/01 - 2014/02/01 Genetica humana Genética Humana e Doenças Infecciosas (Doutoramento) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2011/09/01 - 2014/02/01 Genética Humana Ciências da Vida (Curso de doutoramento (conclusão de unidades curriculares)) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2009/02/01 - 2013/06/01 Genética Medicina (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Membro de associação

Nome da associação Tipo de participação
2010/04/01 - Atual BioDiversity4All - Associação Biodiversidade para Todos Membro da direção

Revisão ad hoc de artigos em revista

Nome da revista (ISSN) Editora
2023/11 - 2023/11 Frontiers in Neurology
2023/10 - 2023/10 Current Research in Neurobiology
2023/09 - 2023/09 Journal of Neurology
2023/03 - 2023/03 Biomolecules
2023/03 - 2023/03 Frontiers in Neurology
2023/03 - 2023/03 Journal of the Neurological Sciences
2022/11 - 2022/11 Frontiers in Neurology
2022/10 - 2022/10 Journal of Personalized Medicine
2022/07 - 2022/07 Scientific Reports
2022/06 - 2022/06 Molecular Neurobiology
2022/06 - 2022/06 Phenomics
2022/05 - 2022/05 Scientific Reports
2022/03 - 2022/03 Annals of Medicine
2022 - 2022 Neurology Research International
2021/11 - 2021/11 Frontiers in Neurology
2021/11 - 2021/11 Medicina
2021/10 - 2021/10 Journal of Neurology
2021 - 2021 Journal of the Neurological Sciences
2020/10 - 2020/10 Annals of Translational Medicine
2020 - 2020 The Journal of Integrative Neuroscience
2018/09/19 - 2018/10/23 Translational Neurodegeneration (2047-9158) Springer (Biomed Central Ltd.)
2015 - 2015 Genetic Testing and Molecular Biomarkers

Tutoria

Tópico Nome do aluno
2019/10 - Atual PhD Thesis: Spasticity in Amyotrophic Lateral Sclerosis: predicting and evaluating treatment impact with non-invasive electrical stimulation Mariana Fernandes Alves Pereira
Distinções

Prémio

2021 ENCALS Poster Awards for Best Rapid Fire Poster Presentation
ENCALS - European Network to Cure ALS, Países Baixos

Outra distinção

2008 PosDoc Grant - SFRH/BPD/39046/2007 - Resistance to Imatinib treatment in Chronic Mieloid Leukemia: characterization of the mechanisms involved.
2008 Ciência 2008 contract
Fundação para a Ciência e a Tecnologia, Portugal
2000 PhD Grant - SFRH/BD/1028/2000 - Genome polyploidisation in the Iberian fish complex Squalius alburnoides. A case study of evolution-in-action through hybridisation and non-sexuality: a cytogenetic approach.
1999 Research Grant - PRAXIS/C/BIA/11086/1998