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João O. Malva is a neuroscientist with research experience in fundamental mechanisms of neuromodulation, neuroprotection, neuroinflammation and neural stem cell-based repair. In the last decade, he strongly invested in neuroscience aspects of ageing and its implications to societal impact. He is the founder of Ageing@Coimbra consortium, a Reference Site of the Innovation Partnership on Active and Healthy Ageing. This strong network activity at regional and european level launched the basis for the negotiation of the admission of the University of Coimbra as a Core Partner of EIT Health. João Malva acted as President of the Portuguese Society for Neuroscience (2007-2011), has acted as a member of the University Senate, Assembly and Scientific Council of the Faculty of Medicine and Institute of Interdisciplinary Research of the University of Coimbra. He is currently elected member of the Parliament of the Municipality of Coimbra.
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Identificação

Identificação pessoal

Nome completo
João Malva

Nomes de citação

  • Malva, João
  • Malva JO
  • João O. Malva

Identificadores de autor

Ciência ID
ED13-3899-FF98
ORCID iD
0000-0002-5438-4447

Telefones

Telefone
  • 239480029 (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Português (Idioma materno)
Francês Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A2) Utilizador independente (B1)
Espanhol; Castelhano Utilizador independente (B1) Utilizador independente (B2) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2009/12/06
Concluído
 Biomedicina (Título de Agregado)
Especialização em Biomedicina
Universidade de Coimbra Faculdade de Medicina, Portugal
1997
Concluído
 Biologia (Doutoramento)
Especialização em Especialidade: Biologia Celular
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Acção Moduladora do Glutamato Nos Terminais Nervosos do Hipocampo de Rato - Identificação de um Receptor de Cainato na Subregião Ca3" (TESE/DISSERTAÇÃO)
1983/09/01 - 1987/07/31
Concluído
 Biologia (Licenciatura)
Universidade de Coimbra, Portugal
 15
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2016/01 - Atual Investigador Coordenador (carreira) (Investigação) Universidade de Coimbra, Portugal
2015 - 2018 Investigador visitante (Investigação) Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brasil
Faculdade de Medicina da Universidade Federal do Ceara, Brasil
2002/03 - 2016/01 Investigador principal (carreira) (Investigação) Universidade de Coimbra Faculdade de Medicina, Portugal
1999/06 - 2002/03 Investigador Auxiliar (carreira) (Investigação) Universidade de Coimbra Faculdade de Medicina, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
1997/06 - 1999/03 Professor Auxiliar (Docente Universitário) Universidade do Minho, Portugal
1989/10 - 1997/06 Assistente (Docente Universitário) Universidade do Minho, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2016 - Atual Coordenação ou direção de centro de investigação, departamento ou equivalente Universidade de Coimbra, Portugal
2021/09/01 - 2022/08/31 Member Scientific Council Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2013 - 2015 Subdirector de Unidade Orgânica Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2020/07/01 - Atual Membro de Conselho Científico Universidade de Coimbra, Portugal
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2015 - 2017 Membro de Conselho Científico Universidade de Coimbra, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
2011 - 2014 Membra de Assembleia de Faculdade (secretário) Universidade de Coimbra, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
Projetos

Bolsa

Designação Financiadores
1997/06/01 - 1997/11/30 Não disponível
PRAXIS XXI/BPD/11786/97
 Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2019/01/01 - Atual Ageing@EITHealth PhD School
20588
Investigador responsável
Universidade de Coimbra Faculdade de Medicina, Portugal
 Comissão Europeia
Em curso
2023/01/01 - 2026/12/31 CHAngeing: Connected Hubs in Ageing: Healthy Living to Protect Cerebrovascular Function
HORIZON-WIDERA-2022-ACCESS-04-01
Investigador responsável
Universidade de Coimbra Faculdade de Medicina, Portugal
Em curso
2023/03/12 - 2026/03/11 Desigualdades sócio-espaciais na demência
2022.04684.PTDC
Universidade de Coimbra, Portugal

Universidade NOVA de Lisboa, Portugal

Universidade de Aveiro, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2021/01/01 - 2025/12/31 Centro de Inovação em Biomedicina e Biotecnologia - Laboratório Associado
LA/P/0058/2020
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2021/01/01 - 2025/12/31 Center for Innovative Biomedicine and Biotechnology - Associate Laboratory
10.54499/LA/P/0058/2020
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2020/01/01 - 2023/12/31 EIT Health Ageing PhD School
...
Investigador responsável
Universidade de Coimbra Faculdade de Medicina, Portugal
 EIT Health
Em curso
2020/11/01 - 2022/12/31 Healthy loneliness - Development of a training program for improving QoL of seniors living in loneliness through educational activities
2020-1-ES01-KA204-083167
Investigador responsável
Universidade de Coimbra, Portugal
Em curso
2021/01/01 - 2021/12/31 URBHEALTH: Urbanisation and Health Summer Course and MOOC
210801
Centro de Estudos em Geografia e Ordenamento do Território, Portugal
 EIT Health
Em curso
2018/07/26 - 2021/07/25 Neurotoxicidade do metilmercúrio nos nichos neurogénicos do cérebro adulto: neurogeneração crónica e declínio cognitivo.
PTDC/MED-TOX/31699/2017
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018/07/01 - 2021/06/30 Neurotoxicity of methylmercury in the neurogenic niches of the adult brain (MercuMemory)
FCT-POCI-01-0145-FEDER-031699
Investigador responsável
Universidade de Coimbra Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2020/01/01 - 2020/12/31 Healthy Loneliness
20515
Investigador
Universidade de Coimbra Faculdade de Medicina, Portugal
 Comissão Europeia
Em curso
2020/01/01 - 2020/12/31 MercuMemory: Methylmercury neurotoxicity in adult brain neurogenic niches: chronic neurogeneration and cognitive decline.
POCI-01-0145-FEDER-031699
Concluído
2015/07 - 2020/06 Enhancing Research in Ageing at the University of Coimbra
grant.669088
Investigador responsável
Universidade de Coimbra Faculdade de Medicina, Portugal
 European Commission
Em curso
2019/01/01 - 2019/12/31 CNC. IBILI
UID/NEU/04539/2019
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal

Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2018/01/31 - 2019/12/31 Caregiving and Ageing Reimagined for Europe (CARE)
18256
19156
Investigador
Universidade de Coimbra Faculdade de Medicina, Portugal
 Comissão Europeia
Concluído
2018/01/01 - 2019/12/31 Healthy Life Style Quarters for Cities and Citizens (HeaLIQs4Cities)
18036
19142
Investigador
Universidade de Coimbra Faculdade de Medicina, Portugal
 Comissão Europeia
Concluído
2015/06 - 2017/05 Stimulating Innovative Polypharmacy Management in the Elderly (SIMPATHY)
663082
 EU Framework Programme for Research and Innovation Health Demographic Change and Wellbeing
2015/06 - 2016/05 Multidisciplinary Institute for Ageing
grant.664629
Investigador responsável
Universidade de Coimbra Faculdade de Medicina, Portugal
 European Commission
2014/04/01 - 2015/09/30 A sabedoria do faminto: modulação por ghrelina da neurogénese e da sua relação com a memória
EXPL/NEU-SCC/1193/2013
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2014/03/01 - 2015/09/30 Ageing@Coimbra: Um Centro de Co-localização na Rede Europeia de Conhecimento e Inovação para o Envelhecimento Saudável e Ativo
EIT-KIC/IVE/0043/2013
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Administração Regional de Saúde do Centro IP, Portugal

Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal

Universidade de Coimbra, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2014/04 - 2015/09 Hunger wisdom: ghrelin modulation of adult neurogenesis and its relationship with memory
Provided by PTCRIS: 134218
 Fundação para a Ciência e a Tecnologia, I.P.
2014/03 - 2015/09 Ageing@Coimbra: A Co-location Centre in the European Knowledge and Innovation Network for Active and Healthy Ageing
Provided by PTCRIS: 135805
 Fundação para a Ciência e a Tecnologia, I.P.
2010/05/01 - 2013/12/31 Alimentos Fucncionais para Neuroprotecção: um papel para o Hypericum perforatum
PTDC/AGR-ALI/105169/2008
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade do Minho, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal

Universidade Católica Portuguesa, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2010/05 - 2013/12 Functional foods for neuroprotection: a role to Hypericum perforatum (Hyperi-Food)
Provided by PTCRIS: 105169
 Fundação para a Ciência e a Tecnologia, I.P.
2010/02 - 2013/07 NPwhY - Innervation and angiogenesis for the benefit of osteogenesis: the involvement of NPY neuronal pathway in bone repair
Provided by PTCRIS: 101469
PTDC/SAU-OSM/101469/2008
Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Faculdade de Medicina, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Garvan Institute of Medical Research, Austrália

Centre Hospitalier Universitaire Vaudois Service de pharmacologie clinique, Suiça

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia, I.P.

Fundação para a Ciência e a Tecnologia
Concluído
2010/04/01 - 2013/06/30 Regeneração cardíaca com células vasculares embrionárias e uma matriz biomimética
PTDC/SAU-BEB/098468/2008
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2010/04/01 - 2013/06/30 Papel da comunicação intercelular entre células endoteliais e celulas estaminais neurais na "stemness" e a neurogénese: novos alvos terapeuticos para a reparação cerebral
PTDC/SAU-NEU/101783/2008
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2010/04 - 2013/06 Heart regeneration by embryonic vascular cells and a biomimetic scaffold
Provided by PTCRIS: 98468
 Fundação para a Ciência e a Tecnologia, I.P.
2010/04 - 2013/06 Role of intercellular communication between endothelial and stem cells in stemness and neurogenesis: new targets for brain repair therapies.
Provided by PTCRIS: 101783
 Fundação para a Ciência e a Tecnologia, I.P.
2010/04/01 - 2013/03/31 Histamina versus anti-histamínicos: novos moduladores da neurogénese?
PTDC/SAU-NEU/104415/2008
Provided by PTCRIS: 104415
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2011/01/01 - 2012/12/31 Projecto Estratégico - LA 1 - 2011-2012
PEst-C/SAU/LA0001/2011
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2007/11 - 2010/10 Search for the molecular basis of transthyretin involvement in the biology of the nervous system.
Provided by PTCRIS: 64437
 Fundação para a Ciência e a Tecnologia, I.P.
2007/05/01 - 2010/09/30 Alterações na Microglia e Neurónios do Hipocampo Induzidas por Metanfetamina: Papel das Citocinas Pró-inflamatórias e do Neuropeptídeo Y
PTDC/SAU-FCF/67053/2006
Universidade do Porto Faculdade de Farmácia, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2007/05 - 2010/09 Microglial and Neuronal Changes in the Hippocampus Induced by Methamphetamine: Role of Pro-inflammatory Cytokines and Neuropeptide Y
Provided by PTCRIS: 67053
 Fundação para a Ciência e a Tecnologia, I.P.
2007/05/01 - 2010/04/30 Células estaminais da região subventricular na reparação cerebral em epilepsia do lobo temporal
PTDC/SAU-NEU/68465/2006
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2007/05 - 2010/04 Subventricular zone stem cells as a tool for brain repair in temporal lobe epilepsy
Provided by PTCRIS: 68465
 Fundação para a Ciência e a Tecnologia, I.P.
2005/09 - 2008/08 Neo-neurogenesis and Microglia in Temporal Lobe Epilesy: Role of Pro-inflammatory Cytokines and Neuropeptide Y in Neuroprotection of New Neurons
Provided by PTCRIS: 58492
POCI/SAU-NEU/58492/2004
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia, I.P.

Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em revista
  1. Reinaldo B. Oriá; Raul S. Freitas; Cássia R. Roque; José Carlos R. Nascimento; Ana Paula Silva; João O. Malva; Richard L. Guerrant; Michael P. Vitek. "ApoE Mimetic Peptides to Improve the Vicious Cycle of Malnutrition and Enteric Infections by Targeting the Intestinal and Blood-Brain Barriers". Pharmaceutics (2023): https://doi.org/10.3390/pharmaceutics15041086.
    10.3390/pharmaceutics15041086
  2. Tyciane S. Nascimento; Daniel V. Pinto; Ronaldo pereira dias; Ramon S. Raposo; Paulo Iury Gomes Nunes; Cássia R. Roque; Flavia Santos; et al. "Chronic Methylmercury Intoxication Induces Systemic Inflammation, Behavioral, and Hippocampal Amino Acid Changes in C57BL6J Adult Mice". International Journal of Molecular Sciences (2022): https://www.mdpi.com/1422-0067/23/22/13837.
    10.3390/ijms232213837
  3. Azul, Anabela Marisa; Almendra, Ricardo; Quatorze, Marta; Loureiro, Adriana; Reis, Flávio; Tavares, Rui; Mota-Pinto, Anabela; et al. "Unhealthy lifestyles, environment, well-being and health capability in rural neighbourhoods: a community-based cross-sectional study". BMC Public Health 21 1 (2021): http://dx.doi.org/10.1186/s12889-021-11661-4.
    10.1186/s12889-021-11661-4
  4. Leocádio, Paola Caroline L.; Lopes, Synara C.; Dias, Ronaldo P.; Alvarez-Leite, Jacqueline I.; Guerrant, Richard L.; Malva, João O.; Oriá, Reinaldo B.. "The Transition From Undernutrition to Overnutrition Under Adverse Environments and Poverty: The Risk for Chronic Diseases". Frontiers in Nutrition 8 (2021): http://dx.doi.org/10.3389/fnut.2021.676044.
    10.3389/fnut.2021.676044
  5. Novo, João P.; Martins, Beatriz; Raposo, Ramon S.; Pereira, Frederico C.; Oriá, Reinaldo B.; Malva, João O.; Fontes-Ribeiro, Carlos. "Cellular and Molecular Mechanisms Mediating Methylmercury Neurotoxicity and Neuroinflammation". International Journal of Molecular Sciences 22 6 (2021): 3101. http://dx.doi.org/10.3390/ijms22063101.
    10.3390/ijms22063101
  6. Raposo RDS; Pinto DV; Moreira R; Dias RP; Fontes Ribeiro CA; Oriá RB; Malva JO. "Methylmercury Impact on Adult Neurogenesis: Is the Worst Yet to Come From Recent Brazilian Environmental Disasters?". Frontiers in aging neuroscience (2020): http://europepmc.org/abstract/med/33328968.
    10.3389/fnagi.2020.591601
  7. Pinto DV; Raposo RS; Matos GA; Alvarez-Leite JI; Malva JO; Oriá RB. "Methylmercury Interactions With Gut Microbiota and Potential Modulation of Neurogenic Niches in the Brain.". Frontiers in neuroscience (2020): http://europepmc.org/abstract/med/33224022.
    10.3389/fnins.2020.576543
  8. Bousquet J; Anto JM; Bachert C; Haahtela T; Zuberbier T; Czarlewski W; Bedbrook A; et al. "ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice.". Allergy (2020): http://europepmc.org/abstract/med/32512619.
    10.1111/all.14422
  9. Oriá RB; Empadinhas N; Malva JO. "Editorial: Interplay Between Nutrition, the Intestinal Microbiota and the Immune System.". Frontiers in immunology (2020): http://europepmc.org/abstract/med/32849628.
    10.3389/fimmu.2020.01758
  10. Cortes L; Malva J; Rego AC; Pereira CF. "Calcium Signaling in Aging and Neurodegenerative Diseases 2019.". International journal of molecular sciences (2020): http://europepmc.org/abstract/med/32046230.
    10.3390/ijms21031125
  11. Santana P; Freitas Â; Stefanik I; Costa C; Oliveira M; Rodrigues TC; Vieira A; et al. "Advancing tools to promote health equity across European Union regions: the EURO-HEALTHY project.". Health research policy and systems (2020): http://europepmc.org/abstract/med/32054540.
    10.1186/s12961-020-0526-y
  12. Bédard A; Antó JM; Fonseca JA; Arnavielhe S; Bachert C; Bedbrook A; Bindslev-Jensen C; et al. "Correlation between work impairment, scores of rhinitis severity and asthma using the MASK-air® App.". Allergy (2020): http://europepmc.org/abstract/med/31995656.
    10.1111/all.14204
  13. Marcus Oliveira; Gabriela Arrifano; Amanda Lopes-Araújo; Leticia Santos-Sacramento; Priscila Y. Takeda; Anthony DC; João O. Malva; Maria Elena Crespo-Lopez. "What Do Microglia Really Do in Healthy Adult Brain?". Cells (2019): https://www.mdpi.com/2073-4409/8/10/1293.
    10.3390/cells8101293
  14. Reis F; Sá-Moura B; Guardado D; Couceiro P; Catarino L; Mota-Pinto A; Veríssimo MT; et al. "Development of a Healthy Lifestyle Assessment Toolkit for the General Public.". Frontiers in medicine (2019): http://europepmc.org/abstract/med/31316985.
    10.3389/fmed.2019.00134
  15. Bédard A; Basagaña X; Anto JM; Garcia-Aymerich J; Devillier P; Arnavielhe S; Bedbrook A; et al. "Mobile technology offers novel insights into the control and treatment of allergic rhinitis: The MASK study.". The Journal of allergy and clinical immunology (2019): http://europepmc.org/abstract/med/30951790.
    10.1016/j.jaci.2019.01.053
  16. Bousquet J; Bedbrook A; Czarlewski W; Onorato GL; Arnavielhe S; Laune D; Mathieu-Dupas E; et al. "Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma.". Clinical and translational allergy (2019): http://europepmc.org/abstract/med/30911372.
    10.1186/s13601-019-0252-0
  17. Menditto E; Costa E; Midão L; Bosnic-Anticevich S; Novellino E; Bialek S; Briedis V; et al. "Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study.". Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2019): http://europepmc.org/abstract/med/30597673.
    10.1111/cea.13333
  18. Augusto-Oliveira M; Arrifano GPF; Malva JO; Crespo-Lopez ME. "Adult Hippocampal Neurogenesis in Different Taxonomic Groups: Possible Functional Similarities and Striking Controversies.". Cells (2019): http://europepmc.org/abstract/med/30764477.
    10.3390/cells8020125
  19. Bousquet J; Illario M; Farrell J; Batey N; Carriazo AM; Malva J; Hajjam J; et al. "The Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Ageing.". Translational medicine @ UniSa (2019): http://europepmc.org/abstract/med/31360670.
  20. Bosnic-Anticevich, Sinthia; Costa, Elisio; Menditto, Enrica; Lourenço, Olga; Novellino, Ettore; Bialek, Slawomir; Briedis, Vitalis; et al. "ARIA pharmacy 2018: Allergic rhinitis care pathways for community pharmacy". (2019): http://hdl.handle.net/10400.6/9359.
    10.1111/all.13701
  21. Bousquet, J Jean; Schünemann, Holger J; Togias, Alkis; Erhola, Marina; Hellings, Peter W; Zuberbier, Torsten; Agache, Ioana; et al. "Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases". (2019): http://hdl.handle.net/10400.6/9365.
    10.1186/s13601-019-0279-2
  22. Bousquet, Jean; Pham-Thi, Nhân; Bedbrook, Anna; Agache, Ioana; Annesi-Maesano, Isabella; Ansotegui, Ignacio; Anto, Josep M; et al. "Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 1)". (2019): http://hdl.handle.net/10400.6/9366.
    10.21037/jtd.2019.08.64
  23. Bousquet J; Arnavielhe S; Bedbrook A; Bewick M; Laune D; Mathieu-Dupas E; Murray R; et al. "MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence.". Clinical and translational allergy (2018): http://europepmc.org/abstract/med/30386555.
    10.1186/s13601-018-0227-6
  24. Oriá RB; Malva JO; Foley PL; Freitas RS; Bolick DT; Guerrant RL. "Revisiting Inbred Mouse Models to Study the Developing Brain: The Potential Role of Intestinal Microbiota.". Frontiers in Human Neuroscience (2018): http://europepmc.org/abstract/med/30283311.
    10.3389/fnhum.2018.00358
  25. Bousquet J; Hellings PW; Agache I; Amat F; Annesi-Maesano I; Ansotegui IJ; Anto JM; et al. "Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology.". The Journal of allergy and clinical immunology (2018): http://europepmc.org/abstract/med/30273709.
    10.1016/j.jaci.2018.08.049
  26. Samreth D; Arnavielhe S; Ingenrieth F; Bedbrook A; Onorato GL; Murray R; Almeida R; et al. "Geolocation with respect to personal privacy for the Allergy Diary app - a MASK study.". The World Allergy Organization Journal (2018): http://europepmc.org/abstract/med/30061979.
    10.1186/s40413-018-0194-3
  27. Malva JO; Amado A; Rodrigues A; Mota-Pinto A; Cardoso AF; Teixeira AM; Todo-Bom A; et al. "The Quadruple Helix-Based Innovation Model of Reference Sites for Active and Healthy Ageing in Europe: The Ageing@Coimbra Case Study.". Frontiers in medicine (2018): http://europepmc.org/abstract/med/29868588.
    10.3389/fmed.2018.00132
  28. McIntosh J; Alonso A; MacLure K; Stewart D; Kempen T; Mair A; Castel-Branco M; et al. "A case study of polypharmacy management in nine European countries: Implications for change management and implementation.". PloS one (2018): http://europepmc.org/abstract/med/29668763.
    10.1371/journal.pone.0195232
  29. Bousquet J; Agache I; Aliberti MR; Angles R; Annesi-Maesano I; Anto JM; Arnavielhe S; et al. "Transfer of innovation on allergic rhinitis and asthma multimorbidity in the elderly (MACVIA-ARIA) - EIP on AHA Twinning Reference Site (GARD research demonstration project).". Allergy (2018): http://europepmc.org/abstract/med/28600902.
    10.1111/all.13218
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    10.1023/A:1025618324593
  105. Rebola N; Pinheiro PC; Oliveira CR; Malva JO; Cunha RA. "Subcellular localization of adenosine A(1) receptors in nerve terminals and synapses of the rat hippocampus.". (2003): http://europepmc.org/abstract/med/14499945.
    10.1016/S0006-8993(03)03247-5
  106. Rego AC; Monteiro NM; Silva AP; Gil J; Malva JO; Oliveira CR. "Mitochondrial apoptotic cell death and moderate superoxide generation upon selective activation of non-desensitizing AMPA receptors in hippocampal cultures.". (2003): http://europepmc.org/abstract/med/12887678.
    10.1046/j.1471-4159.2003.01898.x
  107. Malva JO; Vieira AP; Ambrósio AF; Oliveira CR. "Cobalt staining of hippocampal neurons mediated by non-desensitizing activation of AMPA but not kainate receptors.". (2003): http://europepmc.org/abstract/med/12858045.
    10.1097/00001756-200305060-00014
  108. Silva AP; Carvalho AP; Carvalho CM; Malva JO. "Functional interaction between neuropeptide Y receptors and modulation of calcium channels in the rat hippocampus.". (2003): http://europepmc.org/abstract/med/12623227.
    10.1016/S0028-3908(02)00382-9
  109. Pinheiro PS; Rodrigues RJ; Silva AP; Cunha RA; Oliveira CR; Malva JO. "Solubilization and immunological identification of presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in the rat hippocampus.". (2003): http://europepmc.org/abstract/med/12499049.
    10.1016/S0304-3940(02)01217-X
  110. Silva, Ana P.; Pinheiro, Paulo S.; Carvalho, Arsélio P.; Carvalho, Caetana M.; Jakobsen, Birthe; Zimmer, Jens; Malva, João O.; et al. "Activation of neuropeptide Y receptors is neuroprotective against excitotoxicity in organotypic hippocampal slice cultures". (2003): http://hdl.handle.net/10316/12831.
    10.1523/JNEUROSCI.1510-05.2005
  111. Malva, J.O.; Vieira, A.P.; Oliveira, C.R.; Malva JO; Vieira AP; Oliveira CR. "Understanding the physiology of glutamate receptors by use of a protocol for neuronal staining". American Journal of Physiology - Advances in Physiology Education 27 1-4 (2003): 78-85. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346502965&partnerID=MN8TOARS.
  112. Sequeira, S.M.; Malva, J.O.; Carvalho, A.P.; Carvalho, C.M.. "Presynaptic N-methyl-D-aspartate receptor activation inhibits neurotransmitter release through nitric oxide formation in rat hippocampal nerve terminals". Molecular Brain Research 89 1-2 (2001): 111-118. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035906241&partnerID=MN8TOARS.
    10.1016/S0169-328X(01)00069-9
  113. Silva, A.P.; Carvalho, A.P.; Carvalho, C.M.; Malva, J.O.. "Modulation of intracellular calcium changes and glutamate release by neuropeptide Y1 and Y2 receptors in the rat hippocampus: Differential effects in CA1, CA3 and dentate gyrus". Journal of Neurochemistry 79 2 (2001): 286-296. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034770180&partnerID=MN8TOARS.
    10.1046/j.1471-4159.2001.00560.x
  114. Silva, A.P.; Malva, J.O.; Ambrósio, A.F.; Salgado, A.J.; Carvalho, A.P.; Carvalho, C.M.. "Role of kainate receptor activation and desensitization on the [Ca2+]i changes in cultured rat hippocampal neurons". Journal of Neuroscience Research 65 5 (2001): 378-386. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035448626&partnerID=MN8TOARS.
    10.1002/jnr.1164
  115. Ambrósio, A.F.; Silva, A.P.; Malva, J.O.; Soares-da-Silva, P.; Carvalho, A.P.; Carvalho, C.M.. "Inhibition of glutamate release by BIA 2-093 and BIA 2-024, two novel derivatives of carbamazepine, due to blockade of sodium but not calcium channels". Biochemical Pharmacology 61 10 (2001): 1271-1275. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035873841&partnerID=MN8TOARS.
    10.1016/S0006-2952(01)00584-6
  116. Ambrósio, A.F.; Silva, A.P.; Malva, J.O.; Mesquita, J.F.; Carvalho, A.P.; Carvalho, C.M.. "Role of desensitization of AMPA receptors on the neuronal viability and an the [Ca2+](i) changes in cultured rat hippocampal neurons". European Journal of Neuroscience 12 6 (2000): 2021-2031. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034042462&partnerID=MN8TOARS.
    10.1046/j.1460-9568.2000.00091.x
  117. Ambrósio, A.F.; Silva, A.P.; Araújo, I.; Malva, J.O.; Soares-da-Silva, P.; Carvalho, A.P.; Carvalho, C.M.. "Neurotoxic/neuroprotective profile of carbamazepine, oxcarbazepine and two new putative antiepileptic drugs, BIA 2-093 and BIA 2-024". European Journal of Pharmacology 406 2 (2000): 191-201. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034644868&partnerID=MN8TOARS.
    10.1016/S0014-2999(00)00659-2
  118. A. Cunha, R.; Malva, J.O.; Ribeiro, J.A.. "Pertussis toxin prevents presynaptic inhibition by kainate receptors of rat hippocampal [3H]GABA release". FEBS Letters 469 2-3 (2000): 159-162. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034629239&partnerID=MN8TOARS.
    10.1016/S0014-5793(00)01272-2
  119. Cunha, R.A.; Malva, J.O.; Ribeiro, J.A.. "Kainate receptors coupled to G(i)/G(o) proteins in the rat hippocampus". Molecular Pharmacology 56 2 (1999): 429-433. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032793961&partnerID=MN8TOARS.
  120. Ambrósio, A.F.; Silva, A.P.; Malva, J.O.; Soares-Da-Silva, P.; Carvalho, A.P.; Carvalho, C.M.. "Carbamazepine inhibits L-type Ca2+ channels in cultured rat hippocampal neurons stimulated with glutamate receptor agonists". Neuropharmacology 38 9 (1999): 1349-1359. http://www.scopus.com/inward/record.url?eid=2-s2.0-18244425608&partnerID=MN8TOARS.
    10.1016/S0028-3908(99)00058-1
  121. Malva, João O.; Ambrósio, António F.; Carvalho, Arsélio P.; Carvalho, Caetana M.. "Increase of the intracellular Ca2+ concentration mediated by transport of glutamate into rat hippocampal synaptosomes: characterization of the activated voltage sensitive Ca2+ channels". (1998): http://hdl.handle.net/10316/5472.
  122. Malva, João O.; Carvalho, Arsélio P.; Carvalho, Caetana M.. "Kainate receptors in hippocampal CA3 subregion: evidence for a role in regulating neurotransmitter release". (1998): http://hdl.handle.net/10316/5471.
  123. Malva, J.O.; Carvalho, A.P.; Carvalho, C.M.. "Commentary: Kainate receptors in hippocampal CA3 subregion: Evidence for a role in regulating neurotransmitter release". Neurochemistry International 32 1 (1998): 1-6. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031606083&partnerID=MN8TOARS.
    10.1016/S0197-0186(97)00046-6
  124. Malva, J.O.; Ambrsio, A.F.; Carvalho, A.P.; Carvalho, C.M.. "Commentary: Increase of the intracellular Ca2+ concentration mediated by transport of glutamate into rat hippocampal synaptosomes: Characterization of the activated voltage sensitive Ca2+ channels". Neurochemistry International 32 1 (1998): 7-16. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031594364&partnerID=MN8TOARS.
    10.1016/S0197-0186(97)00048-X
  125. Sequeira, S.M.; Ambrósio, A.F.; Malva, J.O.; Carvalho, A.P.; Carvalho, C.M.. "Modulation of glutamate release from rat hippocampal synaptosomes by nitric oxide". Nitric Oxide - Biology and Chemistry 1 4 (1997): 315-329. http://www.scopus.com/inward/record.url?eid=2-s2.0-0345451156&partnerID=MN8TOARS.
    10.1006/niox.1997.0144
  126. Ambrósio, A.F.; Malva, J.O.; Carvalho, A.P.; Carvalho, C.M.. "Inhibition of N-, P/Q- and other types of Ca2+ channels in rat hippocampal nerve terminals by the adenosine A1 receptor". European Journal of Pharmacology 340 2-3 (1997): 301-310. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344813710&partnerID=MN8TOARS.
    10.1016/S0014-2999(97)01451-9
  127. Malva, J.O.; Carvalho, A.P.; Carvalho, C.M.. "Domoic acid induces the release of glutamate in the rat hippocampal CA3 sub-region". NeuroReport 7 7 (1996): 1330-1334. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029679826&partnerID=MN8TOARS.
  128. Malva, J.; Carvalho, A.; Çarvalho, C.. "Identification of a presynaptic kainate receptor which modules the exocytotic release of glutamate in rat hippocampal CA3 synaptosomes". FASEB Journal 10 3 (1996): http://www.scopus.com/inward/record.url?eid=2-s2.0-33748975701&partnerID=MN8TOARS.
  129. Carvalho, C.; Ambrócio, A.; Malva, J.; Carvlho, A.. "Modulation oh intracellular ca2+ and exocytotic glulamate release by adhnosinh a1 rhchptor activation in the hippocampus". FASEB Journal 10 3 (1996): http://www.scopus.com/inward/record.url?eid=2-s2.0-25744431605&partnerID=MN8TOARS.
  130. Ambrósio, A.F.; Malva, J.O.; Carvalho, A.P.; Carvalho, C.M.. "Modulation of Ca2+ channels by activation of adenosine A1 receptors in rat striatal glutamatergic nerve terminals". Neuroscience Letters 220 3 (1996): 163-166. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030595814&partnerID=MN8TOARS.
    10.1016/S0304-3940(96)13252-3
  131. Carvalho, C.M.; Ferreira, I.L.; Duarte, C.B.; Malva, J.O.; Tretter, L.; Adam-Vizi, V.; Carvalho, A.P.. "Relation of [Ca2+]i to dopamine release in striatal synaptosomes: role of Ca2+ channels". Brain Research 669 2 (1995): 234-244. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028839020&partnerID=MN8TOARS.
  132. Malva, J.O.; Ambrósio, A.F.; Cunha, R.A.; Ribeiro, J.A.; Carvalho, A.P.; Carvalho, C.M.. "A functionally active presynaptic high-affinity kainate receptor in the rat hippocampal CA3 subregion". Neuroscience Letters 185 2 (1995): 83-86. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028912732&partnerID=MN8TOARS.
  133. Carvalho, C.M.; Malva, J.O.; Duarte, C.B.; Carvalho, A.P.. "Characterization of voltage-sensitive Ca2+ channels activated by presynaptic glutamate receptor stimulation in hippocampus". Annals of the New York Academy of Sciences 757 (1995): 457-459. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029129986&partnerID=MN8TOARS.
    10.1111/j.1749-6632.1995.tb17505.x
  134. Malva, J.O.; Carvalho, A.P.; Carvalho, C.M.. "Modulation of dopamine and noradrenaline release and of intracellular Ca2+ concentration by presynaptic glutamate receptors in hippocampus". British Journal of Pharmacology 113 4 (1994): 1439-1447. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027968075&partnerID=MN8TOARS.
  135. Malva, J.O.; Lopes, M.C.F.; Vale, M.G.P.; Carvalho, A.P.. "Action of antiestrogens on the (Ca2+ + Mg2+)-ATPase and Na+/Ca2+ exchange of brain cortex membranes". Biochemical Pharmacology 40 8 (1990): 1877-1884. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025196039&partnerID=MN8TOARS.
Artigo em revista (magazine)
  1. Malva J. "Necrotic-like BV-2 microglial cell death due to methylmercury exposure", Front Pharmacol . , 2022
    10.3389/fphar.2022.1003663
Capítulo de livro
  1. João O. Malva; Ricardo Moreira; Corte Real Martins, Beatriz; Ramon Raposo; Frederico Pereira; Reinaldo Oriá; Carlos Fontes Ribeiro. "Neuroinflammation and ageing". In Assessments, Treatments and Modelling in Aging and Neurological Disease: The Neuroscience of Aging, editado por Elsevier, 139-151. Academic Press - Elsevier, 2021.
    Publicado
  2. João O. Malva; Beatriz Martins; Ricardo Moreira; Novo, João Pedro; Frederico C. Pereira; Ramon Raposo; Reinaldo oriá; Fontes Ribeiro CA. "Neuroinflammation in the elderly". In Assessments, Treatments and Modeling in Aging and Neurological Disease: The Neuroscience of Aging, editado por Colin Martin; Victor Preedy; Rajkumar Rajendram, 139-148. Londres, Reino Unido: Academic Press - Elsevier, 2021.
    Publicado
  3. Pinto, A; Veríssimo, M.; Malva, João. Autor correspondente: Pinto, A. "Patologia Cardíaca Crónica no Idoso". In Manual do Cuidador - Envelhecimento Ativo e Saudável. Coimbra, Portugal: Imprensa da Universidade de Coimbra, 2019.
    Publicado
  4. Malva JO. "Neurogénese e Terapia Celular do Cérebro". In Neurociências, editado por Rego AC; Duarte CB; Oliveira CR, 641-662. Portugal: Lidel, 2017.
    Publicado
  5. Valero, Jorge; Eiriz, Maria Francisca; Santos, Tiago; Neiva, Ismael; Ferreira, Raquel; Malva, João O.. "Microglia: The Bodyguard and the Hunter of the Adult Neurogenic Niche". In Advances in Stem Cell Research, 245-279. Humana Press, 2012.
    Publicado • 10.1007/978-1-61779-940-2_14
  6. Grade, Sofia; Agasse, Fabienne; Bernardino, Liliana; Malva, João O.. "Functional Identification of Neural Stem Cell-Derived Oligodendrocytes". In Methods in Molecular Biology, 165-178. Humana Press, 2012.
    10.1007/978-1-61779-815-3_11
  7. Malva JO. "Inflammation and neurogenesis". In Encyclopedia of Neuroscience, 2676-2680. Heidelberg, Alemanha: Springer, 2008.
    Publicado
  8. Malva, João O.; Bernardino, Liliana. "Inflammation and Neuronal Susceptibility to Excitotoxic Cell Death". In Interaction Between Neurons and Glia in Aging and Disease, 3-35. Springer US, 2007.
    10.1007/978-0-387-70830-0_1
  9. Agasse, Fabienne; Bernardino, Liliana; Malva, João O.. "Subventricular Zone Cells as a Tool for Brain Repair". In Interaction Between Neurons and Glia in Aging and Disease, editado por Malva JO, 81-108. Springer US, 2007.
    10.1007/978-0-387-70830-0_4
Edição de livro
  1. Aging. Aging: from Fundamental Biology to Societal Impact. Elsevier. 2023.
    10.1016/c2020-0-00576-1 • Editor
  2. Pinto, Anabela Mota; Veríssimo, Manuel; Malva, João. Manual do Cuidador. Imprensa da Universidade de Coimbra. 2019.
    10.14195/978-989-26-1851-7
  3. Santana, Paula (ed.). Atlas of population health in European Union regions. Imprensa da Universidade de Coimbra. 2017.
    10.14195/978-989-26-1463-2
  4. Malva JO. Polypharmacy Management by 2030: a patient safety challenge. Coimbra, Portugal. 2017.
    Publicado • Editor
  5. Malva JO. Interaction Between Neurons and Glia in Aging and Disease. Springer US. 2007.
    10.1007/978-0-387-70830-0
Poster em conferência
  1. Élisa Fonseca; Novo, João Pedro; Corte Real Martins, Beatriz; Raposo, Ramon; Frederico C. Pereira; Reinaldo B. Oriá; Carlos Fontes-Ribeiro; João O. Malva. "Neurotoxicity and molecular effects of acute Methylmercury exposure in Microglial Cells". Trabalho apresentado em XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  2. Élisa Fonseca; Novo, João Pedro; Corte Real Martins, Beatriz; Raposo, Ramon; Frederico C. Pereira; Reinaldo B. Oriá; Fontes Ribeiro C; João O. Malva. "Acute Methylmercury exposure induces Neurotoxicity and Microglial Cell Death". Trabalho apresentado em V Symposium Portuguese Glial Network 2021, 2021.
  3. Novo, João Pedro; Beatriz Martins; Ramon Raposo; Frederico C. Pereira; Reinaldo Oriá; João O. Malva; Fontes Ribeiro CA. "The Effect Of Methylmercury On Microglia Inflammatory Responses". Trabalho apresentado em SPF Meeting 2021, 2021.
  4. Beatriz Martins; Novo, João Pedro; Ricardo Moreira; Ramon Raposo; Frederico C. Pereira; Reinaldo Oriá; João O. Malva; Fontes Ribeiro CA. "The Impact Of Methylmercury On Microglia-Derived Neuroinflammation And Neurogenesis". Trabalho apresentado em I International CAPES Print Symposium in Neurosciences and III Simpósio Luso-Brasileiro de Neurociências, 2020.
  5. Beatriz Martins; Novo, João Pedro; João O. Malva; Fontes Ribeiro CA; Ana Paula Pereira da Silva Martins; Frederico Pereira; Reinaldo oriá. "Mercumemory: the effect of methylmercury exposure in microglia-mediated neuroinflammation". Trabalho apresentado em XIV European Meeting on Glial Cells in Health and Disease, 2019.
  6. Beatriz Martins; Novo, João Pedro; Ana Paula Pereira da Silva Martins; Frederico Pereira; Reinaldo oriá; Fontes Ribeiro CA; João O. Malva. "Unraveling the effect of methylmercury exposure in neuroinflammation and neurogenesis". Trabalho apresentado em Sociedade Portuguesa de Neurociências Meeting, 2019.
  7. Martins, Beatriz; João O. Malva; Fontes Ribeiro CA; Pereira, Frederico. "UNRAVELING THE EFFECT OF METHYLMERCURYEXPOSURE IN NEUROINFLAMMATION". Trabalho apresentado em XIV European Meeting on Glial Cells in Health and Disease., 2018.
  8. Xapelli S; Agasse F; Ribeiro FF; Bernardino L; Schitine CS; Heimann A; Ferro ES; et al. "Induction of oligodendrogenesis by hemopressin in subventricular zone neural stem cell cultures". Trabalho apresentado em ISN/ FENS School 2013, Kolymbari, Creta, Grécia, 2013.
  9. Xapelli S; Agasse F; Ribeiro FF; Bernardino L; Schitine CS; Heimann A; Ferro ES; et al. "Hemopressin as a regulator of oligodendrogenesis in neural stem cell cultures from the subventricular zone". Trabalho apresentado em EMBO Young Scientists¿ Forum, Lisboa, Portugal, 2013.
  10. Xapelli S; Sardà L; Bernardino L; Santos T.; Schitine CS; Cortes L; De Melo Reis RA; et al. "The endocannabinoid system promotes proliferation and neuronal differentiation in murine subventricular zone cell cultures". Trabalho apresentado em 8th World congress of IBRO, Florença, Itália, 2011.
  11. Xapelli S; De Melo Reis RA; Bernardino L; Agasse F; Schitine CS; Cortes L; Heimann A; Ferro ES; Malva JO. "Endocannabinoids mediate neurogenesis in murine subventricular zone Stem/Progenitor Cell Cultures". Trabalho apresentado em 6th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies (SPCE-TC), Biocant-Cantanhede, Portugal, 2011.
  12. Bernardino L; Eiriz MF; Santos T.; Xapelli S; Grade S; Rosa A; Cortes L; et al. "Histamine as a promising proneurogenic factor on subventricular zone stem cells: a new approach for brain repair". Trabalho apresentado em 8th World congress of IBRO, Florença, Itália, 2011.
  13. Santos T.; Ferreira R.; Maia J; Xapelli S; Cortes L; Agasse F; Bragança J; et al. "Neuronal differentiation of neural stem cells by a novel retinoic acid-loaded nanoparticles delivery system". Trabalho apresentado em 8th World congress of IBRO, Florença, Itália, 2011.
  14. Santos T.; Ferreira R.; Maia J; Xapelli S; Cortes L; Agasse F; Bragança J; et al. "Retinoic Acid-Loaded Nanoparticles Induce Neuronal Differentiation of Neural Stem cells". Trabalho apresentado em 12th Meeting of the Portuguese Society for Neuroscience (SPN), Lisboa, Portugal, 2011.
  15. Bernardino L; Eiriz MF; Santos T.; Xapelli S; Grade S; Rosa A; Cortes L; et al. "Histamine as a proneurogenic factor on subventricular zone: a new approach for brain repair therapies". Trabalho apresentado em 12th Meeting of the Portuguese Society for Neuroscience (SPN), Lisboa, Portugal, 2011.
  16. Xapelli S; Bernardino L; Cortes L; Schitine CS; Ferro ES; De Melo Reis RA; Agasse F; Malva JO. "Activation of type 1 cannabinoid receptor (CB1R) induce neurogenesis in the murine subventricular zone". Trabalho apresentado em International Symposium: Stem Cells in Biology and Disease (Estools), Lisboa, Portugal, 2010.
  17. Eiriz MF; Bernardino L; Xapelli S; Grade S; Rosa A; Cortes L; Agasse F; Ferreira L.; Malva JO. "Histamine-releasing PLGA microparticles as a tool to impel brain repair". Trabalho apresentado em International Symposium: Stem Cells in Biology and Disease (Estools), Lisboa, Portugal, 2010.
  18. Schitine CS; Agasse F; Xapelli S; Silva AP; De Melo Reis RA; De Mello FG; Malva JO. "AMPA and ampakines as proneurogenic modulators of progenitors derived from subventricular zone". Trabalho apresentado em FeSBE 2009, XXIV Annual Meeting, São Paulo, Brasil, 2009.
  19. Xapelli S; Bernardino L; Ferreira R.; Grade S; Silva AP; Cavadas C; Grouzmann E; et al. "Interactions between NPY and BDNF in neuroprotection against excitotoxicity: a role for neuron-microglia crosstalk?". Trabalho apresentado em 10th Meeting of the Portuguese Society for Neuroscience (SPN), Ofir, Portugal, 2007.
  20. Cristóvão AJ; Xapelli S; Ferreira R.; Silva B; Grade S; Pinheiro PS; Malva JO. "Zinc in excitotoxic injury in rat hippocampus: role of AMPA and kainate receptors in zinc-induced neuronal and glial cell death". Trabalho apresentado em International Society for Zinc Biology Meeting, Siena, Itália, 2006.
  21. Xapelli S; Hamilton T; Malva JO; Colmers WF. "NPY modulation of Backpropagation-Activated Calcium Currents (BAC) of neocortical layer 5 pyramidal cells". Trabalho apresentado em Bordeaux PENS Training Center, European Synapse Summer School, Bordeaux, França, 2006.
  22. Xapelli S; Bernardino L; Silva AP; Salgado JR; Cavadas C; Grouzmann E; Poulsen FR; et al. "Implication of BDNF in the neuroprotective effect of NPY in mouse hippocampal slice cultures exposed to excitotoxic insults". Trabalho apresentado em 8th International NPY meeting, St. Petersburg, Estados Unidos, 2006.
  23. Pinheiro PS; Xapelli S; Ferreira R.; Cristóvão AJ; Malva JO. "Zinc in excitotoxic injury of CA3 pyramidal neurons of the rat hippocampus: effect on AMPA and kainate receptors at postsynaptic and presynaptic sites". Trabalho apresentado em 9th International Symposium on Metal Ions in Biology and Medicine, Lisboa, Portugal, 2006.
  24. Silva AP; Lourenço J; Xapelli S; Ferreira R.; Oliveira CR; Kristiansen H; Woldbye DP; Malva JO. "Cross-talk between neuropeptide Y and PKC in the modulation of glutamate release in the hippocampus of kainate-induced epileptic rats". Trabalho apresentado em 8th International NPY meeting, St. Petersburg, Estados Unidos, 2006.
  25. Álvaro, Ana Rita ; Raquel Santiago; Pereira, Ana Paula da Silva; Joao O. Malva; Eric Grouzmann; Ana Luísa Carvalho; António F. Ambrósio; et al. "Neuropeptide Y Receptors Modulate [Ca2+]i Changes In Retinal Neural Cells". Trabalho apresentado em The Association for Research in Vision and Ophthalmology¿ (ARVO), 2005.
  26. Xapelli S; Silva AP; Ferreira R.; Bernardino L; Pinheiro P; Zimmer J; Oliveira CR; Malva JO. "NPY Y1 and Y2 receptors activation can rescue neurons following the application of an excitotoxic insult with kainate in rat organotypic hippocampal slice cultures". Trabalho apresentado em Neuro-glia Interaction in Aging and Disease (FENS/Blackwell Summer School), Ofir, Portugal, 2005.
  27. Lourenço J; Xapelli S; Oliveira CR; Malva JO; Silva AP. "Involvement of Protein Kinase C in the modulation of glutamate release mediated by neuropeptide Y2 receptors in the hippocampus of epileptic rats". Trabalho apresentado em Neuro-glia Interaction in Aging and Disease (FENS/Blackwell Summer School), Ofir, Portugal, 2005.
  28. Silva AP; Lourenço J; Xapelli S; Oliveira CR; Malva JO. "Protein kinase C signalling is involved in the modulation of glutamate release mediated by neuropeptide Y2 receptors in the hippocampus of epileptic rats". Trabalho apresentado em 9th Annual meeting of The Portuguese Society for Neuroscience, Luso, Portugal, 2005.
  29. Xapelli S; Bernardino L; Poulsen FR; Jakobsen B; Zimmer J; Malva JO. "A activação do receptor Y2 do NPY protege culturas organotípicas de hipocampo de murganho contra agressões excitotóxicas". Trabalho apresentado em IV Congress of Research in Medicine, Coimbra, Portugal, 2004.
  30. Xapelli S; Bernardino L; Poulsen FR; Jakobsen B; Zimmer J; Malva JO. "Neuropeptide Y2 receptor activation protect mouse organotypic hippocampal slice cultures against excitotoxic insults". Trabalho apresentado em 3rd INMED/TINS Conference (The multiple facets of Gabaregic synapses), La Ciotat, França, 2004.
  31. Xapelli S; Bernardino L; Poulsen FR; Jakobsen B; Zimmer J; Malva JO. "Effect of neuropeptide Y2 receptor activation in AMPA-mediated neuronal death and Brain Derived Neurotrophic Factor expression in mouse organotypic hippocampal slice cultures". Trabalho apresentado em New molecular stratagies to treat neurodegenerative diseases (FEBS advanced course), Ofir, Portugal, 2004.
  32. Xapelli S; Silva AP; Bernardino L; Jakobsen B; Zimmer J; Oliveira CR; Malva JO. "Neuroprotection by neuropeptide Y activation in excitotoxicity and epilepsy". Trabalho apresentado em Brain Damage Repair, Lisboa, Portugal, 2004.
  33. Xapelli S; Bernardino L; Silva AP; Jakobsen B; Zimmer J; Malva JO. "Activation of neuropeptide Y2 and Y5 receptor is neuroprotective against excitotoxicity induced by AMPA in mouse organotypic hippocampal slice cultures". Trabalho apresentado em 7th International NPY meeting, Coimbra, Portugal, 2004.
  34. Malva JO; Silva AP; Xapelli S; Pinheiro PS; Cavadas C; Oliveira CR. "Modulation of presynaptic excitability by kainate and NPY receptors in the rat hippocampus: relevance for epileptogenesis and neuroprotection". Trabalho apresentado em 1st Neuroscience Symposium, Natal, Brasil, 2004.
  35. Silva AP; Xapelli S; Oliveira CR; Malva JO. "Functional interaction between NPY receptors and modulation of glutamate release in control and epileptic rat hippocampus". Trabalho apresentado em 1st Neuroscience Symposium, Natal, Brasil, 2004.
  36. Xapelli S; Bernardino L; Silva AP; Poulsen FR; Jakobsen B; Oliveira CR; Malva JO; Zimmer J. "Involvement of neuropeptide Y2 receptor in neuroprotection and decrease of Brain Derived Neurotrophic Factor expression under excitotoxicity in mouse organotypic hippocampal slice cultures". Trabalho apresentado em XIV Meeting of Portuguese Biochemical Society, Vilamoura, Portugal, 2004.
  37. Xapelli S; Silva AP; Pinheiro PS; Cavadas C; Oliveira CR; Malva JO. "Sub-cellular synaptic distribution of NPY Y2 and Y5 receptor subtypes and NPY levels in rat hippocampal subregions". Trabalho apresentado em 8th Annual meeting of The Portuguese Society for Neuroscience, Curia, Portugal, 2003.
  38. Silva AP; Xapelli S; Oliveira CR; Malva JO. "Modulation of glutamate release by neuropeptide Y receptors activation in hippocampal nerve terminals of control and epileptic rats". Trabalho apresentado em 8th Annual meeting of The Portuguese Society for Neuroscience, Curia, Portugal, 2003.
Relatório
  1. Pardal, António; Peixoto, E.; Quatorze, Marta; Azul, AM; Ramalho-Santos, José; João O. Malva; Santana, Paula; Almendra, Ricardo; Loureiro, Adriana. 2019. DEL09 - Final 2019 Activity report. HeaLIQs4Cities Technical Report.
Resumo em conferência
  1. Fonseca, Élisa; Novo, João Pedro; Corte Real Martins, Beatriz; Raposo, Ramon; Pereira, Frederico; Oriá, Reinaldo B.; Fontes Ribeiro C; João O. Malva. "Necrotic-like BV-2 Microglial cell death induced by acute exposure to Methylmercury". Trabalho apresentado em FENS Forum 2022, Paris, 2022.
    Submetido
  2. Fonseca, Élisa; Novo, João Pedro; Corte Real Martins, Beatriz; Raposo, Ramon; Sardão, Vilma; Oliveira, Paulo; Pereira, Frederico; et al. "BV-2 Microglial cell death induced by acute exposure to Methylmercury". Trabalho apresentado em 56th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI 2022), Bari, 2022.
    Submetido
  3. Fernandez-Llimos, Fernando; Figueiredo, Isabel V.; Castel-Branco, Margarida; Cardoso, Filipa L.; Veríssimo, Manuel; Ribeiro, Carlos F.; Malva, João. "SIMPATHY Consortium. Polypharmacy and Adherence: Key Components of Integrated Care: The case of Portugal". Trabalho apresentado em 16th International Conference on Integrated Care (ICIC16), Barcelona, 2016.
    Publicado
  4. Castel-Branco, Margarida; Caramona, M. Margarida; Malva, João; Veríssimo, Manuel; Fernandez-Llimos, Fernando; Figueiredo, Isabel V.; Caramona, Margarida; et al. "Contribution to creating a Good Practice Guideline for home visits to isolated polypharmacy elderly". Trabalho apresentado em 9th PCNE Working Conference, Mechelen, 2015.
    Publicado
  5. Xapelli S; Agasse F; Ribeiro FF; Bernardino L; Schitine CS; Heimann AS; Ferro ES; et al. "Hemopressin promotes oligodendrogenesis in murine subventricular zone cell cultures". Trabalho apresentado em 24th Biennial Meeting of the International Society for Neurochemistry and the American Society for Neurochemistry, Cancún, 2013.
    Publicado • 10.1111/jnc.12186
  6. Xapelli S; Agasse F; Bernardino L; Schitine CS; Heimann AS; Ferro ES; De Melo Reis RA; Malva JO. "Hemopressin promotes neurogenesis and oligodendrogenesis in murine subventricular zone cell cultures". Trabalho apresentado em Neuroscience 2012 (SfN Meeting), New Orleans, 2012.
    Publicado
  7. Xapelli S; Sardà-Arroyo L; Bernardino L; Santos T.; Schitine CS; Agasse F; Malva JO. "(R)-(+)-Methanandamide stimulates neurogenesis in neural stem/progenitor cell cultures derived from postnatal rodent subventricular zone". Trabalho apresentado em FENS Forum 2012, Barcelona, 2012.
    Publicado
  8. Xapelli S; Sarda L; Bernardino L; Santos T.; Agasse F; Malva JO. "Activation of the cannabinoid CB1 receptor promotes proliferation and neuronal differentiation in murine subventricular zone cell cultures". Trabalho apresentado em 10th European Meeting on Glial Cells in Health and Disease, Prague, 2011.
    Publicado • 10.1002/glia.21210
  9. Xapelli S; Bernardino L; Cortes L; Schitine CS; Ferro ES; De Melo Reis RA; Agasse F; Malva JO. "Type 1 Cannabinoid Receptor Activation Induces Neuronal Differentiation of Subventricular Zone Stem/Progenitor Cell Cultures". Trabalho apresentado em 18th Biennial Meeting of the International Society for Developmental Neuroscience, Estoril, 2010.
    Publicado • 10.1016/j.ijdevneu.2010.07.075
  10. Bernardino L; Eiriz MF; Xapelli S; Grade S; Rosa A.; Cortes L; Agasse F; Ferreira L.; Malva JO. "Histamine is a Proneurogenic Factor on Subventricular Zone Stem/Progenitor Cells: A New Approach for Brain Repair Therapies". Trabalho apresentado em 18th Biennial Meeting of the International Society for Developmental Neuroscience, Estoril, 2010.
    Publicado • 10.1016/j.ijdevneu.2010.07.074
  11. Xapelli S; De Melo Reis RA; Schitine CS; Cortes L; Heimann AS; Ferro ES; Agasse F; Bernardino L; Malva JO. "Cannabinoid type 1 receptor-mediated modulation of murine subventricular zone neurogenesis". Trabalho apresentado em Neuroscience 2010 (SfN Meeting), San Diego, 2010.
    Publicado
  12. Xapelli S; Bernardino L; Cortes L; Schitine CS; De Melo Reis RA; Agasse F; Malva JO. "Type 1 cannabinoid receptor (CB1R) activation promotes neuronal differentiation in murine subventricular zone cell cultures". Trabalho apresentado em FENS Forum 2010, Amsterdão, 2010.
    Publicado
  13. Malva JO; Bernardino L; Eiriz MF; Xapelli S; Grade S; Rosa A.; Cortes L; Agasse F; Ferreira L.. "Histamine-releasing PLGA microparticles promote neuronal differentiation from neural stem cell cultures". Trabalho apresentado em Neuroscience 2010 (SfN Meeting), San Diego, 2010.
    Publicado
  14. Schitine CS; Agasse F; Xapelli S; Silva AP; Reis RAM; De Mello FG; Malva JO. "Ampakines as proneurogenic modulators in murine subventricular zone cell cultures". Trabalho apresentado em Neuroscience 2010 (SfN Meeting), San Diego, 2010.
    Publicado
  15. Bernardino L; Eiriz MF; Xapelli S; Grade S; Rosa A.; Cortes L; Agasse F; Ferreira L.; Malva JO. "Histamine promotes neurogenesis in subventricular zone cell cultures: a new approach for brain repair therapies". Trabalho apresentado em FENS Forum 2010, Amsterdão, 2010.
    Publicado
  16. Bernardino L; Eiriz MF; Xapelli S; Grade S; Cortes L; Agasse F; Ferreira L.; Malva JO. "Histamine released from biocompatible microparticles induce neurogenesis in the murine subventricular zone". Trabalho apresentado em Neuroscience 2009 (SfN Meeting), Chicago, 2009.
    Publicado
  17. Xapelli S; Bernardino L; Ferreira R.; Grade S; Silva AP; Salgado JR; Cavadas C; et al. "Neuroprotective interactions between neuropeptide Y and brain-derived neurotrophic factor: a role for microglia". Trabalho apresentado em FENS Forum 2008, Génova, 2008.
    Publicado
  18. Xapelli S; Bernardino L; Ferreira R.; Grade S; Silva AP; Cavadas C; Grouzmann E; et al. "Interaction between neurons and microglia in NPY and BDNF-mediated neuroprotection against excitotoxicity". Trabalho apresentado em Neuroscience 2007 (SfN Meeting), San Diego, 2007.
    Publicado
  19. Xapelli S; Bernardino L; Silva AP; Cavadas C; Grouzmann E; Poulsen FR; Jakobsen B; et al. "NPY triggers neuroprotection mechanisms following excitotoxic insults in mouse organotypic hippocampal slice cultures". Trabalho apresentado em Neuroscience 2005 (SfN Meeting), Washington, 2005.
    Publicado
  20. Silva AP; Xapelli S; Ferreira R.; Bernardino L; Pinheiro PS; Zimmer J; Oliveira CR; Malva JO. "Activation of neuropeptide Y1 or Y2 receptors can prevent the excitotoxicity induced by kainate in rat organotypic hippocampal slice cultures". Trabalho apresentado em Neuroscience 2005 (SfN Meeting), Washington, 2005.
    Publicado
  21. Vezzani A; Bernardino L; Xapelli S; Silva AP; Poulsen FR; Jakobsen B; Oliveira CR; Zimmer J; Malva JO. "Distinct tumor necrosis factor-alpha (TNF-a) receptor subtypes modulate neuronal survival to excitotoxic injury in mouse organotypic hippocampal slice cultures". Trabalho apresentado em Neuroscience 2005 (SfN Meeting), Washington, 2005.
    Publicado
  22. Xapelli S; Silva AP; Pinheiro PS; Cavadas C; Jakobsen B; Zimmer J; Grouzmann E; Oliveira CR; Malva JO. "Up-regulation of neuropeptide Y2 receptors and Neuropetide Y levels following kainate injection in rats". Trabalho apresentado em FENS Forum 2004, Lisboa, 2004.
    Publicado
  23. Silva AP; Xapelli S; Bernardino L; Poulsen FR; Jakobsen B; Oliveira CR; Malva JO; Zimmer J. "Neuroprotection and decreased of brain derived neurotrophic factor expression mediated by neuropeptide Y2 receptor activation in mouse organotypic hippocampal slice cultures". Trabalho apresentado em Neuroscience 2004 (SfN Meeting), San Diego, 2004.
    Publicado
  24. Malva JO; Bernardino L; Xapelli S; Silva AP; Jakobsen B; Poulsen FR; Oliveira CR; Zimmer J. "Activation of microglia in excitotoxic lesions in organotypic slice cultures of the mouse hippocampus". Trabalho apresentado em Neuroscience 2004 (SfN Meeting), San Diego, 2004.
    Publicado
  25. Bernardino L; Xapelli S; Poulsen FR; Jakobsen B; Zimmer J; Duarte EP; Malva JO. "Effect of Tumor necrosis factor-alpha and Interleukin-1 beta in AMPA-mediated neuronal death in mouse organotypic hippocampal slice cultures". Trabalho apresentado em FENS Forum 2004, Lisboa, 2004.
    Publicado
  26. Silva AP; Xapelli S; Cavadas C; Ffrench-Mullen JM; Oliveira CR; Malva JO. "Modulation of glutamate release and expression of neuropeptide Y receptors in epileptic rats". Trabalho apresentado em Neuroscience 2003 (SfN Meeting), New Orleans, 2003.
    Publicado
Tese / Dissertação
  1. Barbosa, Joana Santos. "In vivo single cell analysis reveals distinct behavior of neural stem and progenitor cells in homeostasis and regeneration in the adult brain". Doutoramento, 2015. http://hdl.handle.net/10316/26444.
  2. Grade, Sofia Cristina de Morais. "Strategies for the use of neural stem cells in brain repair". Doutoramento, 2012. http://hdl.handle.net/10316/21224.
  3. Neiva, Ismael. "Modulatory effects of the chemokine Fractalkine in a model of endotoxin-induced microglial activation". Mestrado, 2012. http://hdl.handle.net/10316/25150.
  4. Rosa, Alexandra Isabel Freitas. "Role of intercellular communication between endothelial and stem cells in stemness and neurogenesis : focus on the soluble factor angiopoietin-1 and direct contact via lamimim-1/a6ß1 integrin and connexin 43 as new targets for brain repair". Doutoramento, 2011. http://hdl.handle.net/10316/17778.
  5. Ferreira, Raquel Margarida da Silva. "Contribution of microglia to neural inflammation : neuropeptide y modulates interleukin-1ß-induced microglia activation". Doutoramento, 2010. http://hdl.handle.net/10316/18175.
  6. Domingues, Helena Sofia de Azevedo. "Role of TH1 and TH17 CD4+ T cell subsets in the pathogenesis of experimental autoimmune encephalomyelitis". Doutoramento, 2010. http://hdl.handle.net/10316/13895.
  7. Silva, Bruno Alexandre Cordeiro. "Potencial neuroprotector de extractos e compostos isolados de Hypericum perforatum". Doutoramento, 2008. http://hdl.handle.net/1822/7605.
  8. Pinheiro, Paulo César da Silva. "Presynaptic kainate receptors in the hippocampus : a critical role for GluR7 at the mossy fiber synapse". Doutoramento, 2006. http://hdl.handle.net/10316/10149.
  9. Silva, Ana Paula Pereira da. "Neurotoxicidade e neuroprotecção no hipocampo : papel dos receptores do neuropeptídeo Y". Doutoramento, 2003. http://hdl.handle.net/10316/10158.
  10. Malva, João José Oliveira. "Acção moduladora do glutamato nos terminais nervosos do hipocampo de rato : identificação de um receptor de cainato na sub-região CA3". Doutoramento, 1997. http://hdl.handle.net/10316/10186.

Propriedade Intelectual

Patente
  1. Xapelli S; Reis R; Malva JO. 2013. "Oligodendrocyte differentiation". Portugal.
    Expirada
  2. Malva JO; Schitine C; Agasse F; Xapelli S; Silva AP; Reis R. 2010. "Process for treating neural stem cells based on ampakines and/or other modulators of ionotropic glutamate receptors, compositions thereof and their use in CNS conditions". Portugal.
    Expirada
Atividades

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2012 - 2015 In vivo single cell analysis reveals distinct behavior of neural stem and progenitor cells in homeostasis and regeneration in the adult brain
Coorientador de Joana Santos Barbosa
Universidade de Coimbra Faculdade de Medicina, Portugal
2010 - 2014 Migration and differentiation of neuronal precursors in the postnatal brain: insights from the subventricular zone and cerebellum
Orientador de Maria Francisca Santos Eiriz
Universidade Nova de Lisboa, Portugal
2010 - 2013 Methamphetamine-induced hippocampal dysfunction: the role of pro-inflammatory cytokines and neuropeptide Y
Coorientador de Joana Teresa Ferreira Gonçalves
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 - 2013 Strategies for the use of neural stem cells in brain repair
Orientador de Sofia Cristina Soares de Morais Grade
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 - 2011 Role of intercelular communication between endotelial and stem cells in stemness and neurogenesis
Coorientador de Alexandra Isabel Freitas Rosa
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2011 Neuropeptide Y modulates interleukin-1beta-induced microglia activation
Orientador de Raquel Margarida da Silva Ferreira
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006 - 2010 Role of TH1 and TH17 CD4+ T cells subsets in the pathogenesis of experimental autoimmune encephalomyelitis
Coorientador de Helena Sofia de Azevedo Domingues
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2004 - 2008 Inflammation in excitotoxic neuronal death and survival: onvolvement of tumor necrosis factor-alpha and interleukin-1beta
Orientador de Liliana Inácio Bernardino
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2004 - 2008 Neuroprotective and antiepileptic role of neuropeptide Y
Orientador de Sara Alves Xapelli
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2003 - 2007 Neuroprotective potential of extracts and compounds isolated from Hypericum perforatum
Coorientador de Bruno Alexandre Cordeiro Silva
Universidade do Minho Escola de Ciências, Portugal
2002 - 2006 Presynaptic kainate receptors in the hippocampus: a critical role for GluR7 at the mossy fiber synapse
Orientador de Paulo César da Silva Pinheiro
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2000 - 2003 Neurotoxicity and neuroprotection in the hippocampus: role of neuropeptide Y receptors
Coorientador de Ana Paula Pereira da Silva
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2019 Christiane Costa Aquino
Arguente
 Christiane Costa Aquino (Doutoramento)
Universidade Federal do Ceará, Brasil
2018 António José Braga Gomes Osório Gomes Salgado
Arguente
 António José Braga Gomes Osório Gomes Salgado (Agregação)
Universidade do Minho Escola de Medicina, Portugal
2018 Raúl de Sousa Freitas
Arguente
 Raúl de Sousa Freitas (Doutoramento)
2017 Andreia de Faria Martins Rosa
Presidente do júri
 Andreia de Faria Martins Rosa (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2015 Ana Sofia Simões Bento Baptista
Vogal
 Ana Sofia Simões Bento Baptista (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2015 Rita Isabel Pedro Aroeira
Arguente
 Rita Isabel Pedro Aroeira (Doutoramento)
Universidade de Lisboa Faculdade de Medicina, Portugal
2015 Casper Gotzche
Arguente
 Casper Gotzche (Doutoramento)
Københavns Universitet Afdeling for Almen Medicin, Dinamarca
2014 Filipa Solange Parreira Lourenço Cardoso
Arguente
 Filipa Solange Parreira Lourenço Cardoso (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2014 António Pinto-Duarte
Arguente
 António Pinto-Duarte (Doutoramento)
Universidade de Lisboa Faculdade de Medicina, Portugal
2013 Clara Maria Pires Costa de Bastos Monteiro
Arguente
 Clara Maria Pires Costa de Bastos Monteiro (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
2012 Helder Rui Cardoso da Cruz
Arguente
 Helder Rui Cardoso da Cruz (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
2012 Catarina Sofia Oliveira Miranda
Arguente
 Catarina Sofia Oliveira Miranda (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011 Armando Cardoso
Arguente
 Armando Cardoso (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
2010 Joana Catarina Cravo Lourenço
Vogal
 Joana Catarina Cravo Lourenço (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010 Márcia Maria de Almeida Aranha
Arguente
 Márcia Maria de Almeida Aranha (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2010 Hamad Ali
Arguente
 Hamad Ali (Doutoramento)
Newcastle University, Reino Unido
2009 Paula Margarida Gomes Canas
Vogal
 Paula Margarida Gomes Canas (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 Robert Nunan
Arguente
 Robert Nunan (Doutoramento)
Solent University, Reino Unido
2009 Michael Decressac
Arguente
 Michael Decressac (Doutoramento)
Université de Poitiers, França
2008 Marta Sofia Carvalho Teixeira Pinto
Arguente
 Marta Sofia Carvalho Teixeira Pinto (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
2007 Ana Filipa Duarte Nunes
Arguente
 Ana Filipa Duarte Nunes (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2007 Diana Lina Jerónimo da Cunha Reis
Arguente
 Diana Lina Jerónimo da Cunha Reis (Doutoramento)
Universidade de Lisboa Faculdade de Medicina, Portugal
2006 Adelaide Maria Afonso Fernandes
Arguente
 Adelaide Maria Afonso Fernandes (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2005 Henrique Manuel Paixão dos Santos Girão
Vogal
 Henrique Manuel Paixão dos Santos Girão (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2000 António Francisco Rosa Gomes Ambrósio
Vogal
 António Francisco Rosa Gomes Ambrósio (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Comissão de avaliação

Descrição da atividade
Tipo de assessoria 		Instituição / Organização Entidade financiadora
2020 - Atual Millenium Science Initiative
Avaliador
 Millenium Science Initiative, Chile
2020 - Atual National Science Center
Avaliador
 National Science Center, Polónia National Science Center
2017 - Atual Bolsas D. Manuel de Mello
Avaliador
 José de Mello Saúde
2015 - Atual Dutch Diabetes Foundation
Avaliador
 Dutch Diabetes Foundation
2015 - Atual Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Avaliador
 Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brasil Conselho Nacional de Desenvolvimento Científico e Tecnológico
2014 - Atual Multisclerosis Research Australia
Avaliador
 Multisclerosis Research Australia, Austrália Multisclerosis Research Australia
2012 - Atual La Comisión Nacional de Investigación Científica y Tecnológica
Avaliador
 La Comisión Nacional de Investigación Científica y Tecnológica (CONICYT), Chile La Comisión Nacional de Investigación Científica y Tecnológica (CONICYT)
2007 - Atual Agency for Science, Technology and Research (A*STAR)
Avaliador
 Agency for Science, Technology and Research (A*STAR) , Singapura Agency for Science, Technology and Research (A*STAR)
2021/01/01 - 2021/01/31 Roteiro Nacional de Infraestruturas _ FCT Aviso 04/SAICT/2020 (PO Norte) Universidade de Coimbra, Portugal
2016/09 - 2016/12 Presidente de Comissão de Avaliação de Unidade de Investigação Científica, HARC, Lodz, Polónia
Avaliador
 Comissão Europeia, Bélgica
2016/09 - 2016/12 Comissão de Avaliação de Unidade de Investigação, ITRIBiS, Sevilha, Espanha; REGPOT
Avaliador
 Comissão Europeia, Bélgica
2013 - 2015 FISM, Italian Multiple Sclerosis Foundation
Avaliador
 Associazione Italiana Sclerosi Multipla, Itália Associazione Italiana Sclerosi Multipla
2014/06 - 2014/09 ERA-Net Neuron
Avaliador
 Comissão Europeia, Bélgica
2012 - 2013 Alzheimer’s Association
Avaliador
 Alzheimer's Association, Estados Unidos Alzheimer's Association
2006 - 2009 Health Research Board
Avaliador
 Health Research Board, Irlanda Health Research Board

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2022/01/01 - Atual Consultor da Fundação La Caixa, em Portugal, para a área do Envelhecimento Obra Social La Caixa, Espanha

Membro de associação

Nome da associação Tipo de participação
2013/01/17 - Atual Ageing@Coimbra Coordenador
2016 - 2019 Reference Site Collaborative Network Treasurer and member of the Executive Committee
2015/03 - 2015/12 InnoStars, EIT Health Deputy Director
2007/05 - 2011/05 Sociedade Portuguesa de Neurociências (SPN) Presidente de Direção
Distinções

Outra distinção

2019 Ageing@Coimbra, Reference Site 4 estrelas
European Innovation Partnership on Active and Healthy Ageing (EIP on AHA), Bélgica
2016 Ageing@Coimbra, Reference Site 3 estrelas
European Innovation Partnership on Active and Healthy Ageing (EIP on AHA), Bélgica
2013 Ageing@Coimbra, Reference Site 2 estrelas
European Innovation Partnership on Active and Healthy Ageing (EIP on AHA), Bélgica