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Bruno Fernando Bras da Silva. Concluiu o Doutoramento em Doutoramento em Química em 2009/07/31 pela Universidade do Porto e Licenciatura em Química, Ramo Científico em 2004/07/28 pela Faculdade de Ciências da Universidade do Porto. Publicou 31 artigos em revistas especializadas. Recebeu 5 prémios e/ou homenagens. Atua nas áreas da Química de Colóides, Química Física e Ciências Médicas e da Saúde com ênfase em Biotecnologia Médica, nomeadamente no desenvolvimento de métodos não-virais de veículação de genes. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: Lipoplexos; Poliplexos; Lipo-poliplexos; microfluidica; Caracterização; Dispersão de pequeno-ângulo de raios-X e neutrões (SAXS e SANS).
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Identificação

Identificação pessoal

Nome completo
Bruno Fernando Bras da Silva

Nomes de citação

  • Silva, Bruno
  • Silva, Bruno F. B.

Identificadores de autor

Ciência ID
F217-9E30-387B
ORCID iD
0000-0002-8997-6311

Domínios de atuação

  • Ciências Exatas - Química - Química de Colóides
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Diagnóstico e Terapias de Base Genética
  • Ciências Exatas - Química - Química Física

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2009/07/31
Concluído
 Doutoramento em Química (Doutoramento)
Universidade do Porto Faculdade de Ciências, Portugal
"Phase Behavior of Asymmetric Catanionic Surfactants: Equilibrium, phase transitions and microstructure" (TESE/DISSERTAÇÃO)
 Aprovado por unanimidade
2004/07/28
Concluído
 Licenciatura em Química, Ramo Científico (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Estudo do Comportamento Termotrópico de Tensioactivos Cataniónicos e Tensioactivos Gemini" (TESE/DISSERTAÇÃO)
 15
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2015/09/01 - Atual Investigador principal (carreira) (Investigação) International Iberian Nanotechnology Laboratory, Portugal
International Iberian Nanotechnology Laboratory, Portugal
2014/03/15 - 2015/08/31 Investigador visitante (Investigação) University of California Santa Barbara, Estados Unidos
University of California Santa Barbara, Estados Unidos
2013/03/01 - 2014/01/31 Pós-doutorado (Investigação) Lunds Universitet Kemicentrum, Suécia
Lunds Universitet Kemicentrum, Suécia
2011/02/01 - 2013/01/31 Pós-doutorado (Investigação) University of California Santa Barbara, Estados Unidos
University of California Santa Barbara, Estados Unidos
2009/10/01 - 2010/06/30 Pós-doutorado (Investigação) Lunds Universitet Kemicentrum, Suécia
Lunds Universitet Kemicentrum, Suécia
Projetos

Projeto

Designação Financiadores
2018/07/16 - 2021/07/15 Microfluidic Layer-by-layer Assembly of Cationic Liposome - Nucleic Acid Nanoparticles for Gene Delivery
POCI-01-0145-FEDER-032520
Investigador responsável
International Iberian Nanotechnology Laboratory, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
Produções

Publicações

Artigo em revista
  1. Gómez-Varela, A.I.; Gaspar, R.; Miranda, A.; Assis, J.L.; Valverde, R.H.F.; Einicker-Lamas, M.; Silva, B.F.B.; De Beule, P.A.A.. "Fluorescence cross-correlation spectroscopy as a valuable tool to characterize cationic liposome-DNA nanoparticle assembly". Journal of Biophotonics 14 1 (2021): e202000200. http://www.scopus.com/inward/record.url?eid=2-s2.0-85091730406&partnerID=MN8TOARS.
    Publicado • 10.1002/jbio.202000200
  2. Azevedo, M.A.; Cerqueira, M.A.; Fuciños, P.; Silva, B.F.B.; Teixeira, J.A.; Pastrana, L.. "Rhamnolipids-based nanostructured lipid carriers: Effect of lipid phase on physicochemical properties and stability". Food Chemistry 344 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85097087539&partnerID=MN8TOARS.
    10.1016/j.foodchem.2020.128670
  3. Ricardo Gaspar; Filipe Coelho; Bruno F. B. Silva. "Lipid-Nucleic Acid Complexes: Physicochemical Aspects and Prospects for Cancer Treatment". Molecules 25 21 (2020): 5006. https://www.mdpi.com/1420-3049/25/21/5006.
    Acesso aberto • Publicado • 10.3390/molecules25215006
  4. Paris, Juan L.; Coelho, Filipe; Teixeira, Alexandra; Diéguez, Lorena; Silva, Bruno F. B.; Abalde-Cela, Sara. "In Vitro Evaluation of Lipopolyplexes for Gene Transfection: Comparing 2D, 3D and Microdroplet-Enabled Cell Culture". Molecules 25 14 (2020): 3277. http://dx.doi.org/10.3390/molecules25143277.
    Acesso aberto • Publicado • 10.3390/molecules25143277
  5. Ramalheiro, A.; Paris, J.L.; Silva, B.F.B.; Pires, L.R.. "Rapidly dissolving microneedles for the delivery of cubosome-like liquid crystalline nanoparticles with sustained release of rapamycin". International Journal of Pharmaceutics 591 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85092736220&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2020.119942
  6. Silva, Bruno. "Cubosome nanoparticles for enhanced delivery of mitochondria anticancer drug elesclomol and therapeutic monitoring via sub-cellular NAD(P)H multi-photon fluorescence lifetime imaging". Nano Research (2018): https://doi.org/10.1007/s12274-018-2231-5.
    10.1007/s12274-018-2231-5
  7. Silva, Bruno. "Enhanced magnetic microcytometer with 3D flow focusing for cell enumeration". Lab on a chip (2018): https://pubs.rsc.org/en/content/articlehtml/2018/lc/c8lc00486b.
    10.1039/c8lc00486b
  8. Silva, Bruno. "Unravelling a Mechanism of Action for a Cecropin A-Melittin Hybrid Antimicrobial Peptide: The Induced Formation of Multilamellar Lipid Stacks". Langmuir (2018): https://pubs.acs.org/doi/10.1021/acs.langmuir.7b03639.
    10.1021/acs.langmuir.7b03639
  9. Silva, Bruno; Silva, B.F.B.. "SAXS on a chip: from dynamics of phase transitions to alignment phenomena at interfaces studied with microfluidic devices". Physical Chemistry Chemical Physics 19 35 (2017): 23690-23703. http://pubs.rsc.org/-/content/articlehtml/2017/cp/c7cp02736b.
    10.1039/C7CP02736B
  10. Silva, Bruno. "Recent advances in multiple emulsions and their application as templates". Current Opinion in Colloid & Interface Science (2016): http://www.sciencedirect.com/science/article/pii/S135902941630098X.
    10.1016/j.cocis.2016.07.006
  11. Majzoub, Ramsey N.; Chan, Chia-Ling; Ewert, Kai K.; Silva, Bruno F. B.; Liang, Keng S.; Safinya, Cyrus R.. "Fluorescence microscopy colocalization of lipid-nucleic acid nanoparticles with wildtype and mutant Rab5-GFP: A platform for investigating early endosomal events". Biochimica Et Biophysica Acta-Biomembranes 1848 6 (2015): 1308-1318. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000353747500005&KeyUID=WOS:000353747500005.
    10.1016/j.bbamem.2015.03.001
  12. Silva, Bruno F. B.; Zepeda-Rosales, Miguel; Venkateswaran, Neeraja; Fletcher, Bretton J.; Carter, Lester G.; Matsui, Tsutomu; Weiss, Thomas M.; et al. "Nematic Director Reorientation at Solid and Liquid Interfaces under Flow: SAXS Studies in a Microfluidic Device". Langmuir 31 14 (2015): 4361-4371. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000353177200037&KeyUID=WOS:000353177200037.
    10.1021/la5034614
  13. Silva, Bruno F. B.; Majzoub, Ramsey N.; Chan, Chia-Ling; Li, Youli; Olsson, Ulf; Safinya, Cyrus R.. "PEGylated cationic liposome-DNA complexation in brine is pathway-dependent". Biochimica Et Biophysica Acta-Biomembranes 1838 1 (2014): 398-412. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000330814000033&KeyUID=WOS:000330814000033.
    10.1016/j.bbamem.2013.09.008
  14. Majzoub, Ramsey N.; Chan, Chia-Ling; Ewert, Kai K.; Silva, Bruno F. B.; Liang, Keng S.; Jacovetty, Erica L.; Carragher, Bridget; Potter, Clinton S.; Safinya, Cyrus R.. "Uptake and transfection efficiency of PEGylated cationic liposome-DNA complexes with and without RGD-tagging". Biomaterials 35 18 (2014): 4996-5005. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000335095900013&KeyUID=WOS:000335095900013.
    10.1016/j.biomaterials.2014.03.007
  15. Gentile, Luigi; Silva, Bruno F. B.; Lages, Sebastian; Mortensen, Kell; Kohlbrecher, Joachim; Olsson, Ulf. "Rheochaos and flow instability phenomena in a nonionic lamellar phase". Soft Matter 9 4 (2013): 1133-1140. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000312553900015&KeyUID=WOS:000312553900015.
    10.1039/c2sm27101j
  16. Matos, Marta R. A.; Silva, Bruno F. B.; Marques, Eduardo F.. "Chain length mismatch and packing effects on the thermotropic phase behavior of salt-free catanionic surfactants". Journal of Colloid and Interface Science 405 (2013): 134-144. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000321598400019&KeyUID=WOS:000321598400019.
    10.1016/j.jcis.2013.05.029
  17. Shirazi, Rahau S.; Ewert, Kai K.; Silva, Bruno F. B.; Leal, Cecilia; Li, Youli; Safinya, Cyrus R.. "Structural Evolution of Environmentally Responsive Cationic Liposome-DNA Complexes with a Reducible Lipid Linker". Langmuir 28 28 (2012): 10495-10503. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000306441100023&KeyUID=WOS:000306441100023.
    10.1021/la301181b
  18. Gentile, Luigi; Silva, Bruno F. B.; Balog, Sandor; Mortensen, Kell; Olsson, Ulf. "Structural transitions induced by shear flow and temperature variation in a nonionic surfactant/water system". Journal of Colloid and Interface Science 372 (2012): 32-39. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000301320300005&KeyUID=WOS:000301320300005.
    10.1016/j.jcis.2012.01.027
  19. Silva, Bruno F. B.; Marques, Eduardo F.; Olsson, Ulf; Paul, BK; Moulik, SP. "Unusual Phase Behavior in a Two-Component System Catanionic Surfactant-Water: From Lamellar-Lamellar to Vesicle-Micelle Coexistence". Recent Trends in Surface and Colloid Science 12 (2012): 69-84. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000320922700006&KeyUID=WOS:000320922700006.
  20. Silva, Bruno F. B.; Marques, Eduardo F.; Olsson, Ulf. "Aqueous phase behavior of salt-free catanionic surfactants: the influence of solubility mismatch on spontaneous curvature and balance of forces". Soft Matter 7 1 (2011): 225-236. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000285360200030&KeyUID=WOS:000285360200030.
    10.1039/c0sm00477d
  21. Margulis-Goshen, Katrin; Silva, Bruno F. B.; Marques, Eduardo F.; Magdassi, Shlomo. "Formation of solid organic nanoparticles from a volatile catanionic microemulsion". Soft Matter 7 19 (2011): 9359-9365. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000295085700082&KeyUID=WOS:000295085700082.
    10.1039/c1sm05637a
  22. Silva, Bruno F. B.; Marques, Eduardo F.; Olsson, Ulf. "Fusion and fission of catanionic bilayers". Soft Matter 7 5 (2011): 1686-1689. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000287588800021&KeyUID=WOS:000287588800021.
    10.1039/c0sm01269f
  23. Fernandes, Ricardo M. F.; Marques, Eduardo F.; Silva, Bruno F. B.; Wang, Yujie. "Micellization behavior of a catanionic surfactant with high solubility mismatch Composition, temperature, and salt effects". Journal of Molecular Liquids 157 2-3 (2010): 113-118. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000285234500004&KeyUID=WOS:000285234500004.
    10.1016/j.molliq.2010.08.014
  24. Silva, Bruno F. B.; Marques, Eduardo F.; Olsson, Ulf; Pons, Ramon. "Headgroup Effects on the Unusual Lamellar-Lamellar Coexistence and Vesicle-to-Micelle Transition of Salt-Free Catanionic Amphiphiles". Langmuir 26 5 (2010): 3058-3066. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000274636900016&KeyUID=WOS:000274636900016.
    10.1021/1a902963k
  25. Silva, Bruno F. B.; Marques, Eduardo F.; Olsson, Ulf; Linse, Per. "Size, Shape, and Charge of Salt-Free Catanionic Microemulsion Droplets: A Small-Angle Neutron Scattering and Modeling Study". Journal of Physical Chemistry B 113 30 (2009): 10230-10239. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000268231000027&KeyUID=WOS:000268231000027.
    10.1021/jp901752s
  26. Silva, Bruno F. B.; Marques, Eduardo F.; Olsson, Ulf. "Unusual vesicle-micelle transitions in a salt-free catanionic surfactant: Temperature and concentration effects". Langmuir 24 19 (2008): 10746-10754. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000259673500038&KeyUID=WOS:000259673500038.
    10.1021/la801548s
  27. Silva, Bruno F. B.; Marques, Eduardo F.; Olsson, Ulf. "Lamellar miscibility gap in a binary catanionic surfactant-water system". Journal of Physical Chemistry B 111 48 (2007): 13520-13526. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000251291600008&KeyUID=WOS:000251291600008.
    10.1021/jp076321f
  28. Marques, EF; Brito, RO; Wang, YJ; Silva, BFB. "Thermotropic phase behavior of triple-chained catanionic surfactants with varying headgroup chemistry". Journal of Colloid and Interface Science 294 1 (2006): 240-247. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000233863500028&KeyUID=WOS:000233863500028.
    10.1016/j.jcis.2005.07.021
  29. Fernandes, PA; Maia, ARR; Almeida, AAS; Silva, BFB; Ribeiro, CMS; Ribeiro, CFB; Ribeiro, DSM; et al. "New designs for inhibitors of the NF-kappa B: DNA binding". Theoretical Chemistry Accounts 113 4 (2005): 197-204. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000228895500001&KeyUID=WOS:000228895500001.
    10.1007/s00214-005-0628-1
  30. Silva, BFB; Marques, EF. "Thermotropic behavior of asymmetric chain length catanionic surfactants: The influence of the polar head group". Journal of Colloid and Interface Science 290 1 (2005): 267-274. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000231680700033&KeyUID=WOS:000231680700033.
    10.1016/j.jcis.2005.04.012
  31. Fernandes, PA; Cruz, AIS; Maia, ARR; Almeida, AAS; da Silva, AMN; Silva, BFB; Ribeiro, CMS; et al. "Design of 2-cyclopentenone derivatives with enhanced NF-kappa B: DNA binding inhibitory properties". Journal of Molecular Structure-Theochem 685 1-3 (2004): 73-82. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000225007900005&KeyUID=WOS:000225007900005.
    10.1016/j.theochem.2004.06.027
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2020/06/28 Optimizing The Assembly Of Complex Gene Delivery Formulations With Fluorescence Cross Correlation Spectroscopy Controlled Release Society Virtual Annual Meeting
Controlled Release Society (Virtual, Estados Unidos)
2019/07/23 Size-controlled Formation Of Cubosome Nanoparticles Using Microfluidics Controlled Release Society Annual Meeting & Exposition
Controlled Release Society (Valencia, Espanha)
2019/07/18 Fluorescence Cross-Correlation Spectroscopy as a Valuable Tool to Monitor Cationic Liposome-DNA Nanoparticle Assembly 8th Iberian Meeting on Colloids and Interfaces-RICI8
Grupos de Colóides e Interfaces das Sociedades Portuguesa e Espanhola de Química (Aveiro, Portugal)
2019/07/17 Microfluidics for controlled self-assembly of cubosome nanoparticles of tunable size 8th Iberian Meeting on Colloids and Interfaces-RICI8
Grupos de Colóides e Interfaces das Sociedades Portuguesa e Espanhola de Química (Aveiro, Portugal)
2019/07/17 Pathway-dependent effects on the formation of bioreducible polycation-DNA polyplexes in saline media 8th Iberian Meeting on Colloids and Interfaces-RICI8
Grupos de Colóides e Interfaces das Sociedades Portuguesa e Espanhola de Química (Aveiro, Portugal)
2018/12/11 SAXS on a chip: from alignment phenomena at interfaces to dynamics of phase transitions studied with microfluidic devices Workshop - Scattering and Dynamics of Flowing Soft Material
Lund Institute of Advanced Neutron and X-ray Science (LINXS) (Lund, Suécia)
2018/09/07 SAXS on a chip: from alignment phenomena at interfaces to dynamics of phase transitions studied with microfluidic devices 32nd Conference of the European Colloid and Interface Society
European Colloid and Interface Society (Ljubljana, Eslovénia)
2018/05/29 SAXS-on-a-chip: probing the time evolution of the lamellar-microemulsion transition in a microfluidic device EUSMI/SoftComp Annual Meeting 2018
EUSMI and SoftComp (EU infrastructure networks) (Primosten, Croácia)
2018/03/13 Pathway-dependent effects in the complexation of DNA with PEGylated Cationic Liposomes Polyelectrolytes in Chemistry, Biology and Technology 2018
NTU - Nanyang Technological University, Singapore (Singapura, Singapura)
2017/07/07 Soft self-assembled nanostructured nanoparticles for gene and drug delivery VII Iberian Meeting of Colloids and Interface
Grupos de Colóides e Interfaces das Sociedades Espanhola e Portuguesa de Química (Madrid, Espanha)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2020/12/01 - 2024/11/30 Innovative dual-drug loaded cubosomes to tackle Pseudomonas aeruginosa infections in cystic fibrosis airway environment
Coorientador
 Programa Doutoral Engenharia Biomédica (Doutoramento)
Universidade do Minho, Portugal

International Iberian Nanotechnology Laboratory, Portugal
2020/11/01 - 2024/10/31 Chromene-based molecules for triple negative breast cancer therapy: synthesis, nanoencapsulation and biological studies
Coorientador
Universidade do Minho, Portugal

International Iberian Nanotechnology Laboratory, Portugal
2019/10/01 - 2023/11/30 Microfluidics for size-controlled cationic liposome-DNA complexes: going beyond the universal transfection curve
Coorientador
 Física (MAP-FIS) (Doutoramento)
Universidade do Minho, Portugal

International Iberian Nanotechnology Laboratory, Portugal
2019/10/01 - 2021/05 Microfluidics as nanoassemblers of soft self-assembled nanocarriers for drug delivery
Coorientador
 Biofísica e Bionanossistemas (Mestrado)
Universidade do Minho, Portugal

International Iberian Nanotechnology Laboratory, Portugal
2019/01/01 - 2021/04/15 On-site activation of dual delivery systems for enhanced selectivity and biocompatibility of therapeutic systems
Coorientador
 Programa Doutoral em Química (Doutoramento)
Universidade do Minho, Portugal

Universidade de Vigo, Espanha

International Iberian Nanotechnology Laboratory, Portugal
2020/02/10 - 2020/08/25 Exploring Polycation-DNA complexation for gene delivery using Fluorescence Cross-Correlation Spectroscopy
Coorientador de Xhorxhina Shaulli
 Master in Chemistry from the University of Porto (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal

International Iberian Nanotechnology Laboratory, Portugal
2018/11/06 - 2020/06/25 Monoolein cubosome formation using solvent-exchange in bulk and microfluidics: the effect of DODAB and DDAB addition
Coorientador de Maria Margarida da Silva Costa Barros
 Biofísica e Bionanossistemas (Mestrado)
Universidade do Minho, Portugal

International Iberian Nanotechnology Laboratory, Portugal
2017/10/16 - 2019/03/11 Inhaled therapeutic strategies for cystic fybrosis-associated infections using nanoparticles-based drug delivery
Coorientador de Joana Margarida Dias Domingues
 Master in Biotechnology (Mestrado)
Universidade do Minho, Portugal

International Iberian Nanotechnology Laboratory, Portugal
2017/10/02 - 2018/12/04 Microfluidic methods for the controlled preparation of soft self-assembled nanocarriers for drug delivery
Coorientador de Celso Joel Oliveira Ferreira
 Biofísica e Bionanossistemas (Mestrado)
Universidade do Minho, Portugal

International Iberian Nanotechnology Laboratory, Portugal
2017/01/01 - 2017/11/17 Bulk and Microfluidic-Assisted Preparation of Bioreducible Polyplexes for Gene Therapy
Coorientador de Filipe Coelho
 Mestrado em Química (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal

International Iberian Nanotechnology Laboratory, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2018/12/14 Microfluidic platforms for the validation of new targeted therapies for personalised medicine against osteosarcoma
Arguente principal
 Oihane Mitxelena (Doutoramento)
Centro de Estudios e Investigaciones Técnicas de Gipuzkoa, Espanha

Universidad de Navarra, Espanha
2018/01/31 Development and characterization of cellulose based systems for the entrapment and delivery of probiotic bacteria
Arguente
 Poonam Singh (Doutoramento)
Universidade de Coimbra, Portugal
2017/02/17 Combination of Microfluidics with SAXS for the investigation of pharmaceutical formulations
Arguente principal
 Aghiad Ghazal (Doutoramento)
Københavns Universitet Niels Bohr Instituttet, Dinamarca
Distinções

Outra distinção

2012 MRL-Dow travel fellowship
2010 AXA Research Fund Post-Doctoral Grants (recusei devido a conflito de datas com a bolsa Marie Curie IOF)
Fonds AXA pour la Recherche, França
2010 Marie Curie International Outgoing Fellowship
Research Executive Agency, Bélgica

European Commission, Bélgica
2009 Bolsa no estrangeiro de curta duração
Fundação Calouste Gulbenkian, Portugal
2005 Bolsa de Doutoramento
Fundação para a Ciência e a Tecnologia, Portugal