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Carlos Roca. Completed the Doktor (PhD) in Applied Mathematics in 2009 by Universidad Carlos III de Madrid and Master Universitario in Telecommunication Engineering in 2005 by Universidad Politécnica de Madrid. Is Researcher in Babraham Institute. Published 23 articles in journals. Has 4 section(s) of books. Participates and/or participated as Researcher in 3 project(s). Works in the area(s) of Exact Sciences with emphasis on Computer and Information Sciences with emphasis on Bioinformatics. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: modelling; bioinformatics; network analysis; statistics; transcriptomics; nanomaterials; mathematics; .
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Identificação

Identificação pessoal

Nome completo
Carlos Roca

Nomes de citação

  • Roca, Carlos P.

Identificadores de autor

Ciência ID
F21D-BD45-A5D5
ORCID iD
0000-0003-0230-1926

Websites

Domínios de atuação

  • Ciências Exatas - Ciências da Computação e da Informação - Bioinformática

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Espanhol; Castelhano Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2006 - 2009
Concluído
 Applied Mathematics (Doktor (PhD))
Universidad Carlos III de Madrid, Espanha
 Summa cum laude, unanimous.
2003 - 2005
Concluído
 Telecommunication Engineering (Master Universitario)
Universidad Politécnica de Madrid, Espanha
 Sobresaliente (top grade)
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/01/01 - Atual Investigador (Investigação) Babraham Institute, Reino Unido
University of Cambridge, Reino Unido
2017/11/01 - 2019/03/01 Investigador (Investigação) Vlaams Instituut voor Biotechnologie KU Leuven Center for Cancer Biology, Bélgica
Associatie KU Leuven, Bélgica
2015/08/01 - 2017/10/31 Investigador (Investigação) Aarhus Universitet, Dinamarca
Aarhus Universitet Institut for Bioscience, Dinamarca
2011/12/01 - 2015/07/31 Investigador (Investigação) Universitat Rovira i Virgili, Espanha
Universitat Rovira i Virgili, Espanha
2009/08/01 - 2011/10/01 Investigador (Investigação) Eidgenössische Technische Hochschule Zürich, Suiça
2004/07/01 - 2006/02/28 Investigador (Investigação) National Center for Biotechnology, Espanha

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2005 - 2009 Professor Auxiliar (Docente Universitário) Universidad Carlos III de Madrid Departamento de Matemáticas, Espanha
Universidad Carlos III de Madrid Departamento de Matemáticas, Espanha

Outras Carreiras

Categoria Profissional
Instituição de acolhimento 		Empregador
2001/11/01 - 2004/06/30 Técnico de Informática Grau 2 Nível 2 (Técnico de informática) Military Transport Aircraft Division, EADS-CASA, Espanha
Military Transport Aircraft Division, EADS-CASA, Espanha
Projetos

Projeto

Designação Financiadores
2013/01/01 - Atual MODeling the EnviRonmental and human health effects of Nanomaterials (MODERN)
info:eu-repo/grantAgreement/EC/FP7/309314/EU
Universitat Rovira i Virgili, Espanha
 European Commission
Concluído
2009/03/01 - Atual Quality Collectives: Socially Intelligent Systems for Quality
info:eu-repo/grantAgreement/EC/FP7/231200/EU
Investigador
University of Surrey, Reino Unido
 European Commission
Concluído
2016/07/11 - 2020/03/31 NM-OREO: uso de uma abordagem NM-(bio)molecula cOrona para compReender os mEcanismos de tOxicidade – um estudo de biologia de sistemas de impacto ambiental
PTDC/AAG-MAA/4084/2014
Investigador
Universidade de Aveiro Centro de Estudos do Ambiente e do Mar, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2004 - 2009 3D-EM: Three-Dimensional Electron Microscopy Network of Excellence
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Investigador
European Commission
Concluído
Produções

Publicações

Artigo em conferência
  1. Sánchez, A.; Cuesta, J.A.; Roca, C.P.. "Altruistic behavior pays, or the importance of fluctuations in evolutionary game theory". 2005.
    10.1063/1.2008604
Artigo em revista
  1. Van Nieuwenhove, Erika; Lagou, Vasiliki; Van Eyck, Lien; Dooley, James; Bodenhofer, Ulrich; Roca, Carlos; Vandebergh, Marijne; et al. "Machine learning identifies an immunological pattern associated with multiple juvenile idiopathic arthritis subtypes". Annals of the Rheumatic Diseases 78 5 (2019): 617-628. http://dx.doi.org/10.1136/annrheumdis-2018-214354.
    Publicado • 10.1136/annrheumdis-2018-214354
  2. Susana I.L. Gomes; Carlos P. Roca; Janeck J. Scott-Fordsmand; Mónica J.B. Amorim. "High-throughput transcriptomics: Insights into the pathways involved in (nano) nickel toxicity in a key invertebrate test species". Environmental Pollution 245 (2019): 131-140. https://doi.org/10.1016/j.envpol.2018.10.123.
    10.1016/j.envpol.2018.10.123
  3. Stéphanie Humblet-Baron; John S. Barber; Carlos P. Roca; Aurelie Lenaerts; Pandelakis A. Koni; Adrian Liston. "Murine myeloproliferative disorder as a consequence of impaired collaboration between dendritic cells and CD4 T cells". Blood 133 4 (2019): 319-330. https://doi.org/10.1182/blood-2018-05-850321.
    10.1182/blood-2018-05-850321
  4. Schlenner, Susan; Pasciuto, Emanuela; Lagou, Vasiliki; Burton, Oliver; Prezzemolo, Teresa; Junius, Steffie; Roca, Carlos P; et al. "NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology". Annals of the Rheumatic Diseases 78 3 (2018): 342-349. http://dx.doi.org/10.1136/annrheumdis-2018-213764.
    Publicado • 10.1136/annrheumdis-2018-213764
  5. Susana I. L. Gomes; Carlos P. Roca; Janeck J. Scott-Fordsmand; Mónica J. B. Amorim. "Identifying conserved UV exposure genes and mechanisms". Scientific Reports 8 1 (2018): https://doi.org/10.1038/s41598-018-26865-9.
    10.1038/s41598-018-26865-9
  6. Gomes, Susana I.L.; Gonçalves, Micael F.M.; Bicho, Rita C.; Roca, Carlos P.; Soares, Amadeu M.V.M.; Scott-Fordsmand, Janeck J.; Amorim, Mónica J.B.. "High-throughput gene expression in soil invertebrate embryos – Mechanisms of Cd toxicity in Enchytraeus crypticus". Chemosphere 212 (2018): 87-94. http://dx.doi.org/10.1016/j.chemosphere.2018.08.068.
    Publicado • 10.1016/j.chemosphere.2018.08.068
  7. Susana I. L. Gomes; Carlos P. Roca; Natália Pegoraro; Tito Trindade; Janeck J. Scott-Fordsmand; Mónica J. B. Amorim. "High-throughput tool to discriminate effects of NMs (Cu-NPs, Cu-nanowires, CuNO3, and Cu salt aged): transcriptomics in Enchytraeus crypticus". Nanotoxicology (2018): 1-16. https://doi.org/10.1080/17435390.2018.1446559.
    10.1080/17435390.2018.1446559
  8. Susana I. L. Gomes; Carlos P. Roca; Frank von der Kammer; Janeck J. Scott-Fordsmand; Mónica J. B. Amorim. "Mechanisms of (photo)toxicity of TiO2 nanomaterials (NM103, NM104, NM105): using high-throughput gene expression in Enchytraeus crypticus". Nanoscale (2018): https://doi.org/10.1039/C8NR03251C.
    10.1039/C8NR03251C
  9. Roca, Carlos P.; Gomes, Susana I. L.; Amorim, Mónica J. B.; Scott-Fordsmand, Janeck J.. "Variation-preserving normalization unveils blind spots in gene expression profiling". Scientific Reports 7 1 (2017): http://dx.doi.org/10.1038/srep42460.
    Publicado • 10.1038/srep42460
  10. Susana I. L. Gomes; Carlos P. Roca; Janeck J. Scott-Fordsmand; Mónica J. B. Amorim. "High-throughput transcriptomics reveals uniquely affected pathways: AgNPs, PVP-coated AgNPs and Ag NM300K case studies". Environmental Science: Nano 4 4 (2017): 929-937. https://doi.org/10.1039/C6EN00652C.
    10.1039/C6EN00652C
  11. Chatterjee, Nivedita; Kim, Youngho; Yang, Jisu; Roca, Carlos P.; Joo, Sang-Woo; Choi, Jinhee. "A systems toxicology approach reveals the Wnt-MAPK crosstalk pathway mediated reproductive failure in Caenorhabditis elegans exposed to graphene oxide (GO) but not to reduced graphene oxide (rGO)". Nanotoxicology 11 1 (2016): 76-86. http://dx.doi.org/10.1080/17435390.2016.1267273.
    Publicado • 10.1080/17435390.2016.1267273
  12. Hyun-Jeong Eom; Carlos P. Roca; Ji-Yeon Roh; Nivedita Chatterjee; Jae-Seong Jeong; Ilseob Shim; Hyun-Mi Kim; et al. "A systems toxicology approach on the mechanism of uptake and toxicity of MWCNT in Caenorhabditis elegans". Chemico-Biological Interactions 239 (2015): 153-163. http://dx.doi.org/10.1016/j.cbi.2015.06.031.
    10.1016/j.cbi.2015.06.031
  13. Charles Efferson; Carlos P. Roca; Sonja Vogt; Dirk Helbing. "Sustained cooperation by running away from bad behavior". Evolution and Human Behavior (2015): http://dx.doi.org/10.1016/j.evolhumbehav.2015.05.003.
    10.1016/j.evolhumbehav.2015.05.003
  14. Amorim, M.J.B.; Roca, C.P.; Scott-Fordsmand, J.J.. "Effect assessment of engineered nanoparticles in solid media - Current insight and the way forward". Environmental Pollution (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84949238904&partnerID=MN8TOARS.
    10.1016/j.envpol.2015.08.048
  15. Roca, C.P.; Sánchez, A.; Cuesta, J.A.. "Individual Strategy Update and Emergence of Cooperation in Social Networks". Journal of Mathematical Sociology 36 1 (2012): 1-21. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855934309&partnerID=MN8TOARS.
    10.1080/0022250X.2010.520830
  16. Roca, C.P.; Helbing, D.. "Emergence of social cohesion in a model society of greedy, mobile individuals". Proceedings of the National Academy of Sciences of the United States of America 108 28 (2011): 11370-11374. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960988404&partnerID=MN8TOARS.
    10.1073/pnas.1101044108
  17. Roca, C.P.; Lozano, S.; Arenas, A.; Sánchez, A.. "Topological traps control flow on real networks: The case of coordination failures". PLoS ONE 5 12 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-78650110586&partnerID=MN8TOARS.
    10.1371/journal.pone.0015210
  18. Roca, C.P.; Cuesta, J.A.; Sánchez, A.. "Evolutionary game theory: Temporal and spatial effects beyond replicator dynamics". Physics of Life Reviews 6 4 (2009): 208-249. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350566803&partnerID=MN8TOARS.
    10.1016/j.plrev.2009.08.001
  19. Roca, C.P.; Cuesta, J.A.; Sánchez, A.. "Effect of spatial structure on the evolution of cooperation". Physical Review E - Statistical, Nonlinear, and Soft Matter Physics 80 4 (2009): http://www.scopus.com/inward/record.url?eid=2-s2.0-70350145313&partnerID=MN8TOARS.
    10.1103/PhysRevE.80.046106
  20. Roca, C.P.; Cuesta, J.A.; Sánchez, A.. "Promotion of cooperation on networks? The myopic best response case". European Physical Journal B 71 4 (2009): 587-595. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870781743&partnerID=MN8TOARS.
    10.1140/epjb/e2009-00189-0
  21. Roca, C.P.; Cuesta, J.A.; Snchez, A.. "Imperfect imitation can enhance cooperation". EPL 87 4 (2009): http://www.scopus.com/inward/record.url?eid=2-s2.0-70350242177&partnerID=MN8TOARS.
    10.1209/0295-5075/87/48005
  22. Roca, C.P.; Cuesta, J.A.; Sánchez, A.. "The importance of selection rate in the evolution of cooperation". European Physical Journal: Special Topics 143 1 (2007): 51-58. http://www.scopus.com/inward/record.url?eid=2-s2.0-34249067039&partnerID=MN8TOARS.
    10.1140/epjst/e2007-00070-6
  23. Roca, C.P.; Cuesta, J.A.; Sánchez, A.. "Time scales in evolutionary dynamics". Physical Review Letters 97 15 (2006): http://www.scopus.com/inward/record.url?eid=2-s2.0-33749984231&partnerID=MN8TOARS.
    10.1103/PhysRevLett.97.158701
Capítulo de livro
  1. Brehm, Martin; Kafka, Alexander; Bamler, Markus; Kühne, Ralph; Schüürmann, Gerrit; Sikk, Lauri; Burk, Jaanus; et al. "An Integrated Data-Driven Strategy for Safe-by-Design Nanoparticles: The FP7 MODERN Project". In Advances in Experimental Medicine and Biology, 257-301. Springer International Publishing, 2017.
    Publicado • 10.1007/978-3-319-47754-1_9
  2. Roca, Carlos. "Nanoinformatics for Safe-by-Design Engineered Nanomaterials". 89-107. Royal Society of Chemistry ({RSC, 2012.
    10.1039/9781849735476-00089
  3. Roca, Carlos. "Coordination and Competitive Innovation Spreading in Social Networks". 169â¿¿184-169â¿¿184. Alemanha: Springer Science + Business Media, 2012.
    10.1007/978-3-642-24004-1_9
  4. Roca*, Carlos P.; Rallo, Robert; Fernández, Alberto; Giralt, Francesc. "Chapter 6. Nanoinformatics for Safe-by-Design Engineered Nanomaterials". In Towards Efficient Designing of Safe Nanomaterials, 89-107. Royal Society of Chemistry, 2012.
    Publicado • 10.1039/9781849735476-00089