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Identificação

Identificação pessoal

Nome completo
celso almeida

Nomes de citação

  • almeida, celso

Identificadores de autor

Ciência ID
F91D-9473-15C2
ORCID iD
0000-0002-5935-612X

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Espanhol; Castelhano Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador proficiente (C1)
Alemão Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2011
Concluído
Pharmaceutical Biology / Search novel bioactive secondary metabolites/ from marine fungi (Doutoramento)
Rheinische Friedrich Wilhelms Universität Bonn Fachgruppe Pharmazie, Alemanha
"Novel Secondary Metabolites from Endophytic Marine-derived Fungi (http://hss.ulb.uni-bonn.de/2011/2434/2434.htm)" (TESE/DISSERTAÇÃO)
Magna cum laude
2005
Concluído
Master in Biodiversity and Natural Products (Mestrado)
Universiteit Leiden, Países Baixos
"“Development of a screening method for anthranilate synthase inhibitors & screening for antifungal activity in plants and microflora”." (TESE/DISSERTAÇÃO)
15
2003
Concluído
Biologia (ramo investigação) (Licenciatura)
Universidade de Aveiro, Portugal

Université de Liège, Bélgica
"Two research projects at the University of Liège, Belgium (one year Erasmus program performed in laboratories)" (TESE/DISSERTAÇÃO)
14
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2022/09/01 - 2023/12/30 Investigador Contratado (Investigação) GreenCoLab, Portugal
GreenCoLab, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2020/03/01 - 2022/08/30 Fundador e CEO ENDOBIOS, Portugal
ENDOBIOS, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2018/09/02 - 2020/03/31 Pos doc in the subject of intracellular symbioses of endobacteria in Fungi Universidade de Lisboa Faculdade de Ciências, Portugal
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
2016/03/01 - 2018/09/01 Pos doc in the subject of intracellular symbioses of endobacteria in Fungi Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2014/07/16 - 2016/02/28 Pos doc Marie Curie, european project MICROSMETICS Fundación MEDINA, Espanha
2012/09/01 - 2014/07/15 Pos doc in the subject of intracellular symbioses of endobacteria in Fungi Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
2011/12/01 - 2012/06/30 Pos doc in a project for the search of new antimalaric, antitumoral and antimicrobial natural products from tropical plant endophytic fungi Universidad de Panamá, Panamá
2003/02/03 - 2003/07/30 Internship with the project: ‘Extraction and isolation of Julyprosine and Julyprosopine, two alkaloids from Prosopis juliflora sp.’. Université de Liège, Bélgica
2001/09/14 - 2002/07/30 First semester – ‘Production, Purification and Kinetic analysis of 2 B-lactamases, AmpC P99 and CMY-2’, Second semester – ‘Contribution for the survey of the PR-1D gene at the time of the S.A.R. mec Université de Liège, Bélgica
Projetos

Bolsa

Designação Financiadores
2012/09/01 - 2020/03/30 Endobacterial Mutualistic Symbiosis in Fungi and their Biotechnological Applications
Investigador responsável
Universidade de Lisboa Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Em curso

Projeto

Designação Financiadores
2014/07/01 - 2016/02/29 MICROSMETICS
Investigador
Fundación Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Espanha
European Commission Seventh Framework Programme for Research and Technological Development People
Concluído
Produções

Publicações

Artigo em revista
  1. Mamdouh Nabil Samy; Géraldine Le Goff; Philippe Lopes; Katerina Georgousaki; Sentiljana Gumeni; Celso Almeida; Victor Gonzalez-Menendez; et al. "Elastase inhibitory activity of secondary metabolites from the fungus Virgaria nigra CF-231658". Natural Product Research (2022): https://doi.org/10.1080/14786419.2021.1899175.
    10.1080/14786419.2021.1899175
  2. Celso Almeida. "A potential third-order role of the host endoplasmic reticulum as a contact site in interkingdom microbial endosymbiosis and viral infection". Environmental Microbiology Reports (2021): https://doi.org/10.1111/1758-2229.12938.
    10.1111/1758-2229.12938
  3. Celso Almeida; Margarida D. Amaral. "A central role of the endoplasmic reticulum in the cell emerges from its functional contact sites with multiple organelles". Cellular and Molecular Life Sciences (2020): https://doi.org/10.1007/s00018-020-03523-w.
    10.1007/s00018-020-03523-w
  4. Almeida, Celso; Mackenzie, Thomas Andrew; González-Menéndez, Víctor; de Pedro, Nuria; Pérez-Victoria, Ignacio; Crespo, Gloria; Martín, Jesús; et al. "Laccaridione C, a Bioactive Polyketide from the Fungus Montagnula sp.". Planta Medica International Open 6 02 (2019): e57-e62. http://dx.doi.org/10.1055/a-1032-3346.
    Acesso aberto • Publicado • 10.1055/a-1032-3346
  5. Georgousaki, K.; Tsafantakis, N.; Gumeni, S.; González-Menéndez, V.; de Pedro, N.; Tormo, J.R.; Almeida, C.; et al. "Cercospora sp. as a source of anti-aging polyketides targeting 26S proteasome and scale-up production in submerged bioreactor". Journal of Biotechnology 301 (2019): 88-96. http://www.scopus.com/inward/record.url?eid=2-s2.0-85067227388&partnerID=MN8TOARS.
    10.1016/j.jbiotec.2019.05.015
  6. Samy, M.N.; Goff, G.L.; Lopes, P.; Georgousaki, K.; Gumeni, S.; Almeida, C.; González, I.; et al. "Osmanicin, a polyketide alkaloid isolated from streptomyces osmaniensis CA-244599 inhibits elastase in human fibroblasts". Molecules 24 12 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85067301104&partnerID=MN8TOARS.
    10.3390/molecules24122239
  7. Celso Almeida; Cristina Silva Pereira; Victor Gonzalez-Menendez; Gerald Bills; Javier Pascual; Marina Sánchez-Hidalgo; Stefan Kehraus; Olga Genilloud; Frank E. Löffler. "Unveiling Concealed Functions of Endosymbiotic Bacteria Harbored in the Ascomycete Stachylidium bicolor". Applied and Environmental Microbiology 84 15 (2018): https://doi.org/10.1128/AEM.00660-18.
    10.1128/AEM.00660-18
  8. Almeida, C.; Pérez-Victoria, I.; González-Menéndez, V.; De Pedro, N.; Martín, J.; Crespo, G.; Mackenzie, T.; et al. "Non-geminal Aliphatic Dihalogenation Pattern in Dichlorinated Diaporthins from Hamigera fusca NRRL 35721". Journal of Natural Products 81 6 (2018): 1488-1492. http://www.scopus.com/inward/record.url?eid=2-s2.0-85049031171&partnerID=MN8TOARS.
    10.1021/acs.jnatprod.8b00041
  9. Celso Almeida; Gerald Bills; Víctor González-Menéndez; Jesús Martin; José R. Tormo; Olga Genilloud. "Time-Dependent Production of the Bioactive Peptides Endolides A and B and the Polyketide Mariline A from the Sponge-Derived Fungus Stachylidium bicolor 293K04". Fermentation 3 3 (2017): 45-45. https://doi.org/10.3390%2Ffermentation3030045.
    10.3390/fermentation3030045
  10. Fisch, K.M.; Pereira, C.S.; Genilloud, O.; Almeida, C.; Schäberle, T.F.. "Draft genome sequence of Burkholderia contaminans 293K04B, an endosymbiont of the spongederived fungus Stachylidium bicolor". Genome Announcements 5 45 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85034577887&partnerID=MN8TOARS.
    10.1128/genomeA.01142-17
  11. El Maddah, F.; Kehraus, S.; Nazir, M.; Almeida, C.; König, G.M.. "Insights into the Biosynthetic Origin of 3-(3-Furyl)alanine in Stachylidium sp. 293 K04 Tetrapeptides". Journal of Natural Products 79 11 (2016): 2838-2845. http://www.scopus.com/inward/record.url?eid=2-s2.0-84999143759&partnerID=MN8TOARS.
    10.1021/acs.jnatprod.6b00601
  12. Almeida, C.; El Maddah, F.; Kehraus, S.; Schnakenburg, G.; König, G.M.. "Endolides A and B, vasopressin and serotonin-receptor interacting N-methylated peptides from the sponge-derived fungus stachylidium sp.". Organic Letters 18 3 (2016): 528-531. http://www.scopus.com/inward/record.url?eid=2-s2.0-84957564504&partnerID=MN8TOARS.
    10.1021/acs.orglett.5b03553
  13. Schmitz, A.; Kehraus, S.; Schäberle, T.F.; Neu, E.; Almeida, C.; Roth, M.; König, G.M.. "Corallorazines from the myxobacterium corallococcus coralloides". Journal of Natural Products 77 1 (2014): 159-163. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893045851&partnerID=MN8TOARS.
    10.1021/np400740u
  14. Bouhired, S.M.; Crüsemann, M.; Almeida, C.; Weber, T.; Piel, J.; Schäberle, T.F.; König, G.M.. "Biosynthesis of phenylnannolone A, a multidrug resistance reversal agent from the halotolerant myxobacterium Nannocystis pusilla B150". ChemBioChem 15 5 (2014): 757-765. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896388151&partnerID=MN8TOARS.
    10.1002/cbic.201300676
  15. Almeida, C.; Ortega, H.; Higginbotham, S.; Spadafora, C.; Arnold, A.E.; Coley, P.D.; Kursar, T.A.; Gerwick, W.H.; Cubilla-Rios, L.. "Chemical and bioactive natural products from microthyriaceae sp., an endophytic fungus from a tropical grass". Letters in Applied Microbiology 59 1 (2014): 58-64. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902347352&partnerID=MN8TOARS.
    10.1111/lam.12245
  16. Almeida, C.; El Aouad, N.; Martín, J.; Pérez-Victoria, I.; González-Menéndez, V.; Platas, G.; De La Cruz, M.; et al. "Graminin B, a furanone from the fungus Paraconiothyrium sp.". Journal of Antibiotics 67 5 (2014): 421-423. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901486925&partnerID=MN8TOARS.
    10.1038/ja.2014.11
  17. Almeida, C.; Eguereva, E.; Kehraus, S.; König, G.M.. "Unprecedented polyketides from a marine sponge-associated Stachylidium sp.". Journal of Natural Products 76 3 (2013): 322-326. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875479559&partnerID=MN8TOARS.
    10.1021/np300668j
  18. Almeida, C.; Hemberger, Y.; Schmitt, S.M.; Bouhired, S.; Natesan, L.; Kehraus, S.; Dimas, K.; et al. "Marilines A-C: Novel phthalimidines from the sponge-derived fungus Stachylidium sp.". Chemistry - A European Journal 18 28 (2012): 8827-8834. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863468188&partnerID=MN8TOARS.
    10.1002/chem.201103278
  19. Almeida, C.; Part, N.; Bouhired, S.; Kehraus, S.; König, G.M.. "Stachylines A-D from the sponge-derived fungus stachylidium sp". Journal of Natural Products 74 1 (2011): 21-25. http://www.scopus.com/inward/record.url?eid=2-s2.0-79951521698&partnerID=MN8TOARS.
    10.1021/np1005345
  20. Almeida, C.; Kehraus, S.; Prudêncio, M.; König, G.M.. "Marilones A-C, phthalides from the sponge-derived fungus Stachylidium sp.". Beilstein Journal of Organic Chemistry 7 (2011): 1636-1642. http://www.scopus.com/inward/record.url?eid=2-s2.0-82955222303&partnerID=MN8TOARS.
    10.3762/bjoc.7.192
  21. Almeida, C.; Eguereva, E.; Kehraus, S.; Siering, C.; König, G.M.. "Hydroxylated sclerosporin derivatives from the marine-derived fungus cadophora malorum". Journal of Natural Products 73 3 (2010): 476-478. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950454619&partnerID=MN8TOARS.
    10.1021/np900608d
  22. Almeida, C.; Elsaedi, S.; Kehraus, S.; König, G.M.. "Novel bisabolane sesquiterpenes from the marine-derived fungus Verticillium tenerum". Natural Product Communications 5 4 (2010): 507-510. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953009544&partnerID=MN8TOARS.
  23. Bauvois, C.; Ibuka, A.S.; Celso, A.; Alba, J.; Ishii, Y.; Frère, J.-M.; Galleni, M.. "Kinetic properties of four plasmid-mediated AmpC ß-lactamases". Antimicrobial Agents and Chemotherapy 49 10 (2005): 4240-4246. http://www.scopus.com/inward/record.url?eid=2-s2.0-25844511801&partnerID=MN8TOARS.
    10.1128/AAC.49.10.4240-4246.2005
Distinções

Prémio

2021 EU EIT Health InnoStars Awards (Prémio para a Startup ENDOBIOS)
EIT Health, Alemanha
2020 EU EIT Health InnoStars Awards (Prémio para a Startup ENDOBIOS)
EIT Health, Alemanha

Outra distinção

2009 ASP meeting student travel award (50th American Society of Pharmacognosy conference, Honolulu, june 200), for presenting the work NOVEL SECONDARY METABOLITES FROM THE SPONGE-DERIVED FUNGUS STACHYLIDIUM SP.; TRACKING BACTERIAL ENDOSYMBIONTS
American Society of Pharmacognosy, Estados Unidos
2009 PSE student travel award (6th European Conference for Marine Natural Products, July 2009) given to the work: NOVEL SECONDARY METABOLITES FROM THE SPONGE-DERIVED FUNGUS STACHYLIDIUM SP.; TRACKING BACTERIAL ENDOSYMBIONTS