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PROFILE: A Senior Researcher with extensive experience in Research Project Management within the public and the private sectors. A Highly Collaborative Scientist at the international level with active participation in European Research Networks. A TTO Director with experience and expertise of technology transfer at the academic environment. A Full Professor with teaching skills at the international level. A PhD Degree coupled with a proven track record of publications, patents and contracts with companies. A highly effective negotiator and communicator with great people skills along with strong leadership, problem solving and decision-making abilities and an eye for the bottom-line. ACCOMPLISHMENTS, COLLABORATIONS & LEADERSHIP: I completed my PhD under the supervision of Prof. Víctor S. Martín in the asymmetric synthesis of a variety of biologically active molecules such as lipidic a-amino acids and derivatives, and fused cyclic ethers. I moved to the Vrije Universiteit medisch centrum in Amsterdam (NL), for postdoctoral research with Prof. G. J. Peters getting insight in the molecular pharmacology of anticancer drugs. In 1998, I joined DSM Research in Geleen (NL) to work for three years on the enantioselective membrane separation of pharmaceutically relevant carboxylic acids with Prof. J. G. de Vries. Afterwards, I worked from 2001 to 2003 in Almería (ES) at Deretil in the production of ß-lactam antibiotics. Upon return to the Canary Islands in 2004, I started a screening program aimed at the discovery of new anticancer substances and I successfully established BioLab, an independent research group at ULL. Overall, I coauthored 169 articles in scientific journals collected in the SJR, have participated in numerous congresses with over 200 presentations, co-inventor of 4 granted patents and 1 under evaluation, PI of various competitive funding projects, joined numerous (inter-)national projects, and signed contracts with companies. I have established long-term open collaborations with several academic groups in Europe, Latin-American and Asia. I participate in diverse International Scientific Committees, such as EORTC – Pharmacology and Molecular Mechanisms Group (PAMM) and the Management Committee of COST Actions CM1106, CA15106, CA15135 and CA17104. At BioLab, I have clustered a solid and experienced group of multidisciplinary scientists with expertise in chemistry, biochemistry, pharmacy, engineering and microbiology to develop realistic and collaborative research programs on Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Technology, and Bioprospection of Endemic Plants in the Canary Islands to find therapeutic solutions to human diseases, with a particular focus on -but not limited to- cancer. CONTRIBUTIONS TO SOCIETY: I regularly participate in talks to students from local high schools. I have been interviewed in diverse local and national media to comment on our research and the results. I was appointed Science Communication Manager of COST Action CA17104 and managed all issues related to dissemination of the results of the network including building and keeping updated web pages and social media accounts. I use social media to disseminate the results of our group (@BioLabULL) and from our Institute (@iuboag). Recently, I got the approval of ULL to implement the Transfer Unit BioL4B (BioLab for Business) in order to ease the collaborations with the private sector. TRAINING AND EVALUATION: I have overseen numerous end-of-degree and end-of-master projects, two completed PhD thesis, supervised several postdocs, and over 60 scientific visitors from Europe, Africa and Latin America. I participate as member of the editorial board of diverse scientific journals. I have participated as Advisory Board Member of BioVaria from 2015 to 2017.
Identificação

Identificação pessoal

Nome completo
José Manuel Padrón

Nomes de citação

  • José M. Padrón
  • Padrón, José M.
  • Padrón JM

Identificadores de autor

Ciência ID
FD1A-BFA6-C8FA
ORCID iD
0000-0001-6268-6552
Google Scholar ID
EDAYWm0AAAAJ
Researcher Id
H-5240-2011
Scopus Author Id
7003856521

Telefones

Telefone
  • (+34) 922316502 Ext.: 6126 (Profissional)

Moradas

  • Avenida Astrofísico Francisco Sánchez 2, 38206, La Laguna, La Laguna, Espanha (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia
  • Ciências Exatas - Química - Química Orgânica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2)
Espanhol; Castelhano (Idioma materno)
Formação
Grau Classificação
1991 - 1996/12/17
Concluído
Chemical Structure and Synthesis of Natural Organic Products (Doctor)
Universidad de La Laguna, Espanha
"ASYMMETRICAL SYNTHESIS OF 2,3,5,6-TETRASUBSTITUTED TETRAHYDROFURANS AND LIPIDIC ALPHA-AMINO ACIDS. FIRST SYNTHESIS OF ALPHA-AMINO-ARAQUIDONIC ACID" (TESE/DISSERTAÇÃO)
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2020/12/14 - Atual Professor Catedrático (Docente Universitário) Universidad de La Laguna, Espanha
2017/01/09 - 2020/12/13 Professor Associado (Docente Universitário) Universidad de La Laguna, Espanha
2011/07/01 - 2017/01/08 Professor Auxiliar (Docente Universitário) Universidad de La Laguna, Espanha
2007/01/01 - 2011/06/30 Leitor (Docente Universitário) Universidad de La Laguna, Espanha

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2023/11/08 - Atual Director de Unidade Orgânica Universidad de La Laguna, Espanha
Universidad de La Laguna Instituto Universitario de Bio-Orgánica Antonio González, Espanha
2019/09 - 2023/11/07 Secretary Universidad de La Laguna, Espanha
Universidad de La Laguna Instituto Universitario de Bio-Orgánica Antonio González, Espanha
2013/04 - 2015/05 Director de Unidade Orgânica Universidad de La Laguna, Espanha
Universidad de La Laguna / Technology Transfer Office, Espanha
Projetos

Bolsa

Designação Financiadores
2022/09 - 2026/09 Targeting cell metabolism in pancreatic ductal adenocarcinoma (STARVING)
PID2021-123059OB-I00
Investigador responsável
Ministerio de Economía y Competitividad
Em curso
2020/01 - 2022/09 New therapeutic strategies for the treatment of pancreatic cancer (TheraPanc)
ProID2020010101
Agencia Canaria de Investigación Innovación y Sociedad de la Información
2018/09 - 2022/09 New diagnostic and therapeutic tools against multidrug resistant tumors (STRATAGEM) European Cooperation in Science and Technology
2019/01 - 2021/12 Sustainable Chemistry: from Small Molecules to Complex Functional Systems (SUSCHEM)
PGC2018-094503-B-C22
Gobierno de España Ministerio de Ciencia e Innovación
2018/01 - 2021/12 Inhibition of glutamine metabolism as therapy for pancreatic ductal adenocarcinoma (METAPANC)
Proyecto Agustín de Betancourt
Cabildo Insular de Tenerife
2020/01 - 2021/06 Early pharmacological profile of marine natural products of the Canary Islands' biodiversity (FARMACAN)
EIS 2020 06_ULL
Agencia Canaria de Investigación Innovación y Sociedad de la Información
2019/06 - 2021/05 Preparation of MSC-ITN action Multitargeted therapies against pancreatic ductal adenocarcinoma (PANCNET)
EIN2019-102928
Gobierno de España Ministerio de Ciencia e Innovación
2016/04 - 2020/10 Multi-target paradigm for innovative ligand identification in the drug discovery process (MuTaLig) European Cooperation in Science and Technology
2016/03 - 2020/03 C-H Activation in Organic Synthesis (CHAOS) European Cooperation in Science and Technology
2016/03 - 2019/12 Development of tocopherol-mimetics using environmentally friendly unconventional synthesis methodologies
FCE_1_2014_1_103499
Agencia Nacional de Investigacion e Innovacion
2016/04 - 2019/04 Steroids as an important source for the synthesis of heterosteroids
CB-2015 256495
Consejo Nacional de Ciencia y Tecnología
2015/04 - 2019/04 Enantioselective synthesis of polyoxygenated metabolites with cytotoxic activity
Grupo No. 1063, Proyecto No. 981
Universidad de la República Comisión Sectorial de Investigación
2015/04 - 2018/04 Synthesis of new steroidal derivatives containing heterocycles spiro, substituted or fused to ring C, D or E, and their evaluation as antioxidants and antiproliferative activity
CB-2014 240329
Consejo Nacional de Ciencia y Tecnología
2015/01 - 2017/12 Phytochemical study of Vernonia acuminata
2014-1D4-01
Fondo Nacional De Innovación y Desarrollo Científico y Tecnológico
2014/01 - 2017/12 Anticancer bioprospecting in endemic and native plants Dominicans in the family Asteraceae
2013-1D4-003
Fondo Nacional De Innovación y Desarrollo Científico y Tecnológico
2013/01 - 2016/12 Search for cytotoxic substances from microscopic fungi
CB-2012-01 181820
Consejo Nacional de Ciencia y Tecnología
2013/01 - 2016/12 Phytochemical study of Elekmania buchii
2012-2013-1D3-4
Fondo Nacional De Innovación y Desarrollo Científico y Tecnológico
2012/12 - 2016/05 Improving Biomedical Research and Innovation in the Canary Islands (IMBRAIN) Research Executive Agency
2012/06 - 2016/04 Chemical Approaches to Targeting Drug Resistance in Cancer Stem Cells Research Executive Agency
2013/03 - 2015/02 Development of bioactive molecules using green chemistry methodologies
FCE-2-2011-1-5717
Agencia Nacional de Investigacion e Innovacion
2012/01 - 2014/12 Mechanism of Action of Novel Antitumor Compounds Disruptors of Cell Division
PI11/00840
Instituto de Salud Carlos III
2013/09 - 2014/11 Beyond Imagination: Unveiling the Cellular Universe Fundación Española para la Ciencia y la Tecnología
2012/01 - 2013/06 EORTC-PAMM Group Winter Meeting Ministry of Economy and Competitiveness
2010/12 - 2013/01 Chemoenzymatic synthesis and biological evaluation of oligo-tetrahydrofurans analogous to natural Acetogenins
FCE 2009-3094
Agencia Nacional de Investigacion e Innovacion
2010/04 - 2012/04 Development of new antibacterial and antifungal drugs derived from privileged structures of marine origin
PI43/09
Fundación Canaria de Investigación y Salud
2009/01 - 2012/01 Mechanisms of action of the cytotoxic and/or estrogenic activity of natural phytoestrogens, bioactive lipids and their synthetic analogues
PI2007/021
Agencia Canaria de Investigación Innovación y Sociedad de la Información
2010/01 - 2011/12 Evaluation of molecules of synthetic and natural origin as cytotoxic in search of new leading structures as antitumor drugs
A/025750/09
A/032351/10
Gobierno de Espana Ministerio de Asuntos Exteriores y de Cooperación
2009/01 - 2011/12 Development of new catalytic processes aimed at the synthesis of molecules bioactive
CTQ2008-06806-C02-01/BQU
Gobierno de España
2008/01 - 2011/12 Cooperative Cancer Research Thematic Network (RTICC)
RD06/0020/1046
Instituto de Salud Carlos III
2007/01 - 2011/06 Design, synthesis and antitumor activity of new analogues of privileged structures of marine origin: spisulosin / sphingosine, halogenated cyclic ethers and a,ß-unsaturated ß-hydroxyketones
RYC-2006-001716
Ministerio de Educación y Ciencia
2008/01 - 2011/01 Canary Islands Antitumor Drug Development Network (REDESFAC)
PI01/06
Fundación Canaria de Investigación y Salud
2008/01 - 2011/01 Development of new antitumor drugs derived from privileged structures of marine origin
PI35/06
Fundación Canaria de Investigación y Salud
2005/11 - 2008/11 Efficient construction of privileged structural elements: application to stereoselective synthesis of natural products, biological seeders, and new receptors molecular
CTQ2005-09074-C02-01/BQU
Ministerio de Educación y Ciencia
2006/01 - 2007/12 Obtaining synthetically modified iridoids: theoretical studies and evaluation of their biological activity
A/4014/05
A/6972/06
Gobierno de Espana Ministerio de Asuntos Exteriores y de Cooperación
2006/01 - 2007/12 Stereoselective synthesis of ceramide analogs. Bioactivity evaluation
PROIPRO P20106
Universidad Nacional de San Luis
2006/06 - 2007/06 Implementation of new biological evaluation systems
GC02460601
Gobierno de Canarias
2006 - 2007 Biopolis - Building a European Region
Interreg IIIB 05/MAC/2.3/C14
INTERREG MAC Cooperation Program (Madeira-Azores-Canarias)
2004/05 - 2005/12 Structural and Synthetic Studies of Bioactive Cyclic Ethers of Marine Origin
PPQ2002-04361-C04-02
Gobierno de España
1998/09 - 2001/09 Development of enantioselective receptors for medium to large scale membrane separations of racemic mixtures of carboxylic acid derivatives European Commission
1993/05 - 1996/05 Enantioselective synthesis of biologically active cyclic systems: polyethers, fused g-lactones and 2’,3’-dideoxynucleosides
PB 92-0489
Dirección General de Universidades e Investigación
1993/11 - 1996/01 Endogenous and synthetic inhibitors of phospholipases as medicinal substances European Commission
1991/09 - 1993/12 Total enantioselective synthesis of hemibrevetoxin-b and toxin fragments related
PB 89-0402
Dirección General de Universidades e Investigación

Projeto

Designação Financiadores
2023/01/01 - 2024/06/30 Engaging Libraries of Promising Oxindoles as Tyrosine-Kinase InhibitorS in Cancer Target Therapy
2022.02910.PTDC
Universidad de La Laguna, Espanha

Universidade de Évora, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
Produções

Publicações

Artigo em conferência
  1. Guillermo Valdomir; Juan Ignacio Padrón; Jenny Saldaña; José Manuel Padrón; Gloria Serra; Eduardo Manta; Victor S. Martín; Danilo Davyt. "Synthesis of hybrids compounds by Click Chemistry and their bioactivities". 2013.
    10.5151/chempro-14bmos-r0081-1
  2. Guillermo Valdomir; José M. Padrón; Juan I. Padrón; Víctor S. Martín; Danilo Davyt. "New modular structures constructed by click chemistry". 2013.
    10.5151/chempro-15bmos-bmos2013_201381919619
  3. Markidis, T.; Padron, J.M.; Constantinou, V.; Martin, T.; Martin, V.S.; Kokotos, G.. "Conversion of chiral unsaturated lipidic amino acids into sphingosine analogs and diamines". 1995.
Artigo em revista
  1. Mehul P. Parmar; Anwesha Das; Disha P. Vala; Savan S. Bhalodiya; Chirag D. Patel; Shana Balachandran; Nagesh Kumar Kandukuri; et al. "QSAR, Antimicrobial, and Antiproliferative Study of (R/S)-2-Thioxo-3,4-dihydropyrimidine-5-carboxanilides". ACS Omega (2025): http://dx.doi.org/10.1021/acsomega.4c09899.
    10.1021/acsomega.4c09899
  2. Mónica Martínez-Montiel; Giulia Arrighi; Paloma Begines Aguilar; Aday González-Bakker; Adrián Puerta; Miguel X. Fernandes; Penélope Merino-Montiel; et al. "Multifaceted Sulfonamide-Derived Thiosemicarbazones: Combining Metal Chelation and Carbonic Anhydrases Inhibition in Anticancer Therapy". International Journal of Molecular Sciences (2025): https://www.mdpi.com/1422-0067/26/3/1225.
    10.3390/ijms26031225
  3. Sabotic, Jerica; Puerta, Adrian; Gonzalez-Bakker, Aday; Karnicar, Katarina; Erzar, Eva; Tumpej, Tadeja; Turk, Dusan; Padron, Jose M.. "Fungal lectins show differential antiproliferative activity against cancer cell lines". International Journal of Biological Macromolecules (2025): https://publons.com/wos-op/publon/72692377/.
    10.1016/J.IJBIOMAC.2024.139220
  4. Ahuja-Casarin, Ana I.; Cortes-Percino, Alejandra; Gonzalez-Bakker, Aday; Puerta, Adrian; Merino-Montiel, Penelope; Vega-Baez, Jose Luis; Melendez, Francisco J.; et al. "Development of Steroidal Spiro-Heterocycles Through One-Step Cyclocondensation, Their Evaluation as Antiproliferative Agents". ChemistrySelect (2025): https://publons.com/wos-op/publon/72692372/.
    10.1002/SLCT.202403170
  5. Adrián Puerta; Aday González-Bakker; Eduardo Romanos; Inmaculada Aguilar Domínguez; Mónica Martínez-Montiel; Penélope Merino-Montiel; Raquel P. Herrera; et al. "Multimodal antiproliferative effects of oleanolic acid mitocans: In vitro and in vivo studies". Biochemical Pharmacology (2025): https://publons.com/wos-op/publon/73058493/.
    10.1016/J.BCP.2025.116807
  6. Ana Margarida Janeiro; Aday González-Bakker; José M. Padrón; Carolina S. Marques. "Accessing Promising Passerini Adducts in Anticancer Drug Design". Molecules (2024): https://doi.org/10.3390/molecules29235538.
    10.3390/molecules29235538
  7. Paloma Begines; Alessandro Bonardi; Simone Giovannuzzi; Alessio Nocentini; Paola Gratteri; Viviana De Luca; Aday González-Bakker; et al. "Synthesis and investigation of selective human carbonic anhydrase IX, XII inhibitors using coumarins bearing a sulfonamide or biotin moiety". Chemico-Biological Interactions (2024): https://doi.org/10.1016/j.cbi.2024.111284.
    10.1016/j.cbi.2024.111284
  8. Carolina P. Reyes; Alejandro Ardiles; Laura Anaissi-Afonso; Aday González-Bakker; José M. Padrón; Ignacio A. Jiménez; Félix Machín; Isabel L. Bazzocchi. "Exploring the Anticancer Potential of Phenolic nor-Triterpenes from Celastraceae Species". International Journal of Molecular Sciences (2024): https://doi.org/10.3390/ijms25179470.
    10.3390/ijms25179470
  9. Vanesa Quintana; Aday González-Bakker; Adam N. Khan; Juan I. Padrón; Danilo Davyt; José M. Padrón; Guillermo Valdomir. "Novel tetrahydropyran-triazole hybrids with antiproliferative activity against human tumor cells". Archiv der Pharmazie (2024): https://doi.org/10.1002/ardp.202400431.
    10.1002/ardp.202400431
  10. Carolina S Marques; Aday González-Bakker; José M Padrón. "The Ugi4CR as effective tool to access promising anticancer isatin-based a-acetamide carboxamide oxindole hybrids". Beilstein Journal of Organic Chemistry (2024): https://doi.org/10.3762/bjoc.20.104.
    10.3762/bjoc.20.104
  11. Hamdullah Khadim Sheikh; Cindy Juliet Cristancho Ortiz; Tanzila Arshad; José M. Padrón; Prof. Dr. Haroon Khan. "Advancements in steroidal Pt(II) & Pt(IV) derivatives for targeted chemotherapy (2000–2023)". European Journal of Medicinal Chemistry (2024): http://dx.doi.org/10.1016/j.ejmech.2024.116438.
    10.1016/j.ejmech.2024.116438
  12. Rosalba González-Solís; Guillermo Mendoza; Antero Ramos; Victor M. Bandala; Leticia Montoya; Aday González-Bakker; José M. Padrón; Irene Lagunes; Ángel Trigos. "Antiproliferative and Antibacterial Activity of Polyporoid Fungi from Veracruz, Mexico". International Journal of Medicinal Mushrooms (2024): http://dx.doi.org/10.1615/intjmedmushrooms.2024052840.
    10.1615/intjmedmushrooms.2024052840
  13. Dipakkumar D. Chudasama; Chetan V. Rajput; Manan S. Patel; Jaydeepkumar N. Parekh; Harsh C. Patel; Navin P. Chikhaliya; Adrián Puerta; José M. Padrón; Kesur R. Ram. "Microwave-induced one-pot synthesis of 3-imidazolyl indole clubbed 1,2,3-triazole hybrids as antiproliferative agents and density functional theory study". Archiv der Pharmazie (2024): https://doi.org/10.1002/ardp.202300632.
    10.1002/ardp.202300632
  14. Puerta A; González-Bakker A; Pedro Brandão; Pineiro M; Burke AJ; Giovannetti E; Fernandes MX; Padrón JM. "Early pharmacological profiling of isatin derivatives as potent and selective cytotoxic agents.". Biochemical pharmacology (2024): https://doi.org/10.1016/j.bcp.2024.116059.
    10.1016/j.bcp.2024.116059
  15. Fuentes-Aguilar A; González-Bakker A; Jovanovic M; Stojanov SJ; Puerta A; Gargano A; Jelena Dinic; et al. "Coumarins-lipophilic cations conjugates: Efficient mitocans targeting carbonic anhydrases.". Bioorganic chemistry (2024): https://doi.org/10.1016/j.bioorg.2024.107168.
    10.1016/j.bioorg.2024.107168
  16. Mateusz Olszewski; Maciejewska N; Kallingal A; Chylewska A; Dabrowska AM; Biedulska M; Mariusz Makowski; Padrón JM; Maciej Baginski. "Palindromic carbazole derivatives: unveiling their antiproliferative effect via topoisomerase II catalytic inhibition and apoptosis induction.". Journal of enzyme inhibition and medicinal chemistry (2024): https://europepmc.org/articles/PMC10791108.
    10.1080/14756366.2024.2302920
  17. Vala, Disha P.; Miller, Amy Dunne; Atmasidha, Aditi; Parmar, Mehul P.; Patel, Chirag D.; Upadhyay, Dipti B.; Bhalodiya, Savan S.; et al. "Click-chemistry mediated synthesis of OTBN-1,2,3-Triazole derivatives exhibiting STK33 inhibition with diverse anti-cancer activities". Bioorganic Chemistry (2024): https://publons.com/wos-op/publon/68569645/.
    10.1016/J.BIOORG.2024.107485
  18. Mehul P. Parmar; Disha P. Vala; Savan Bhalodiya; Dipti Upadhyay; Chiragkumar Patel; Subham G. Patel; Srinivasa R. Gandholi; et al. "A green bio-organic catalyst (taurine) promoted one-pot synthesis of (R/S)-2-thioxo-3,4-dihydropyrimidine(TDHPM)-5-carboxanilides: chiral investigations using circular dichroism and validation by computational approaches". RSC Advances (2024): http://dx.doi.org/10.1039/d4ra01391c.
    10.1039/d4ra01391c
  19. Diaz-Vazquez, Eva D.; Cuellar, Micaela A.; Heredia, Micaela D.; Barolo, Silvia M.; Gonzalez-Bakker, Aday; Padron, Jose M.; Buden, Maria E.; Martin, Sandra E.; Uberman, Paula M.. "Palladium nanoparticles for the synthesis of phenanthridinones and benzo[c]chromenes via C-H activation reaction". RSC Advances (2024): https://publons.com/wos-op/publon/68657437/.
    10.1039/D4RA02835J
  20. I. Caroline Vaaland Holmgard; Aday González-Bakker; Eleonora Poeta; Adrián Puerta; Fernandes, M. X.; Barbara Monti; José G. Fernández-Bolaños; et al. "Coumarin–azasugar–benzyl conjugates as non-neurotoxic dual inhibitors of butyrylcholinesterase and cancer cell growth". Organic & Biomolecular Chemistry (2024): http://dx.doi.org/10.1039/d4ob00312h.
    10.1039/d4ob00312h
  21. Gonzalez-Solis, Rosalba; Mendoza, Guillermo; Ramos, Antero; Bandala, Victor M.; Montoya, Leticia; Gonzalez-Bakker, Aday; Padron, Jose M.; Lagunes, Irene; Trigos, Angel. "Antiproliferative and Antibacterial Activity of Polyporoid Fungi from Veracruz, Mexico". International Journal of Medicinal Mushrooms (2024): https://publons.com/wos-op/publon/68417376/.
    10.1615/intjmedmushrooms.2024052840
  22. Sheikh, Hamdullah Khadim; Padron, Jose M.; Arshad, Tanzila; Habib, Uzma; Jamil, Shahnila; Khan, Haroon; Ayub, Khurshid. "New dynamic scoring method for deep evaluation of naloxegol as ß-tubulin binding inhibitor". Pakistan Journal of Pharmaceutical Sciences (2024): https://publons.com/wos-op/publon/71055181/.
    10.36721/PJPS.2024.37.5.REG.949-959.1
  23. Martinez-Lara, Rosa I.; Cobos-Ontiveros, Luis A.; Meza-Ireta, Silvia A.; Martinez-Montiel, Monica; Colin-Lozano, Blanca; Puerta, Adrian; Padron, Jose M.; et al. "Novel Coumarin-Steroid/Terpenoid Hybrids: In Vitro and In Silico Anticancer Studies". Chemistry and Biodiversity (2024): https://publons.com/wos-op/publon/71140004/.
    10.1002/CBDV.202401315
  24. I. Caroline Vaaland; Óscar López; Adrián Puerta; Miguel X. Fernandes; José M. Padrón; José G. Fernández-Bolaños; Magne O. Sydnes; Emil Lindbäck. "Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers". Journal of Enzyme Inhibition and Medicinal Chemistry (2023): https://doi.org/10.1080/14756366.2022.2150762.
    10.1080/14756366.2022.2150762
  25. Tereza Hofmanova; Carolina Marques; Alfonso T. García-Sosa; Óscar López; Luisa Leitzbach; Elisabete P. Carreiro; Aday González-Bakker; et al. "N-Substituted 3-Aminooxindoles and N-Propargyl Derivatives: Potential Biological Activities against Alzheimer’s Disease". Results in Chemistry (2023): https://doi.org/10.1016/j.rechem.2023.101032.
    10.1016/j.rechem.2023.101032
  26. Adrián J. Santiago-Benítez; Adrián Puerta; José M. Padrón; Manuel Norte; José J. Fernández; Antonio Hernández Daranas; Francisco Cen-Pacheco. "Antiproliferative effect of natural and semisynthetic polyethers from Laurencia viridis". Natural Product Research (2023): https://doi.org/10.1080/14786419.2023.2280176.
    10.1080/14786419.2023.2280176
  27. Sutariya TR; Brahmbhatt GC; Atara HD; Parmar NJ; RajniKant; Gupta VK; Irene Lagunes; et al. "An efficient one-pot synthesis and docking studies of bioactive new antiproliferative dispiro[oxindole/acenaphthylenone¿benzofuranone] pyrrolidine scaffolds.". Molecular diversity (2023): https://doi.org/10.1007/s11030-023-10741-4.
    10.1007/s11030-023-10741-4
  28. Subham G. Patel; Paras J. Patel; Dipti B. Upadhyay; Adrián Puerta; Apoorva Malik; Nagesh K. Kandukuri; Rakesh K Sharma; José M. Padrón; Hitendra M. Patel. "Insights into microwave assisted synthesis of spiro-chromeno[2,3-d]pyrimidines using PEG-OSO3H catalyst: DFT study and their antiproliferative activity". Journal of Molecular Structure (2023): https://doi.org/10.1016/j.molstruc.2023.136174.
    10.1016/j.molstruc.2023.136174
  29. María Sol Ballari; Exequiel O. J. Porta; Evelyn Arel Zalazar; Carla M. Borini Etichetti; José M. Padrón; Javier E. Girardini; Guillermo R. Labadie. "Lipophilic modification of salirasib modulates the antiproliferative and antimigratory activity". Bioorganic & Medicinal Chemistry (2023): https://doi.org/10.1016/j.bmc.2023.117417.
    10.1016/j.bmc.2023.117417
  30. Roshanak Shams; Behmanesh A; Mazhar FN; Vaghari AA; Hossein-Khannazer N; Agarwal T; Massoud Vosough; Padrón JM. "Developed Bone Biomaterials Incorporated with MicroRNAs to Promote Bone Regeneration: A Systematic Review, Bioinformatics, and Meta-analysis Study.". ACS biomaterials science & engineering (2023): https://doi.org/10.1021/acsbiomaterials.3c00178.
    10.1021/acsbiomaterials.3c00178
  31. Irene Lagunes; Homero Lumbreras-Martínez; César Espinoza; José M. Padrón; Jorge López-Portillo; Ángel Trigos. "Diversity and bioactivity of sediment-associated fungi from a mangrove forest in Mexico with different conservation conditions". Latin American Journal of Aquatic Research (2023): https://doi.org/10.3856/vol51-issue3-fulltext-2971.
    10.3856/vol51-issue3-fulltext-2971
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  96. Irene Lagunes; Paloma Begines; Adrián Silva; Alexis R. Galán; Adrián Puerta; Miguel X. Fernandes; Inés Maya; et al. "Selenocoumarins as new multitarget antiproliferative agents: Synthesis, biological evaluation and in silico calculations". European Journal of Medicinal Chemistry 179 (2019): 493-501. https://doi.org/10.1016/j.ejmech.2019.06.073.
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  97. Padrón, José. "Antiproliferative potential of 3ß,5a,6ß,7a-tetrahydroxyergosta-8(14),22-diene produced by Acremonium persicinum isolated from an alkaline crater lake in Puebla, Mexico". Natural Product Research (2019): http://dx.doi.org/10.1080/14786419.2019.1669032.
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  98. Elena M. Sánchez-Fernández; M. Isabel García-Moreno; Raquel García-Hernández; José M. Padrón; José M. García Fernández; Francisco Gamarro; Carmen Ortiz Mellet. "Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp2-Iminosugar Glycolipids". Molecules 24 16 (2019): 2882-2882. https://doi.org/10.3390/molecules24162882.
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  99. Sebastián J. Castro; Carina N. Casero; José M. Padrón; Viviana E. Nicotra. "Selective Antiproliferative Withanolides from Species in the Genera Eriolarynx and Deprea". Journal of Natural Products (2019): https://doi.org/10.1021/acs.jnatprod.9b00117.
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  100. Damir Hamulic; Marco Stadler; Steffen Hering; José M. Padrón; Rachel Bassett; Fatima Rivas; Marco A. Loza-Mejía; M. Auxiliadora Dea-Ayuela; Miguel A. González-Cardenete. "Synthesis and Biological Studies of (+)-Liquiditerpenoic Acid A (Abietopinoic Acid) and Representative Analogues: SAR Studies". Journal of Natural Products (2019): https://doi.org/10.1021/acs.jnatprod.8b00884.
    10.1021/acs.jnatprod.8b00884
  101. Dinic, J.; Ríos-Luci, C.; Karpaviciene, I.; Cikotiene, I.; Fernandes, M.X.; Pešic, M.; Padrón, J.M.. "CKT0353, a novel microtubule targeting agent, overcomes paclitaxel induced resistance in cancer cells". Investigational New Drugs (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85067282745&partnerID=MN8TOARS.
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  102. Ingold, M.; Colella, L.; Hernández, P.; Batthyány, C.; Tejedor, D.; Puerta, A.; García-Tellado, F.; et al. "A Focused Library of NO-Donor Compounds with Potent Antiproliferative Activity Based on Green Multicomponent Reactions". ChemMedChem 14 18 (2019): 1669-1683. http://www.scopus.com/inward/record.url?eid=2-s2.0-85071284949&partnerID=MN8TOARS.
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  103. Padrón, J.M.; Emiliano, A.; Castillo, Q.A.. "Secondary Metabolites from Pterocaulon alopecuroides and their Antiproliferative Activities". Pharmacognosy Journal 11 3 (2019): 493-495. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068703450&partnerID=MN8TOARS.
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  104. Luque-Agudo, V.; Albarrán-Velo, J.; Light, M.E.; Padrón, J.M.; Román, E.; Serrano, J.A.; Gil, M.V.. "Synthesis and antiproliferative activity of new 2-glyco-3-nitro-2H-chromenes". Bioorganic Chemistry 87 (2019): 112-116. http://www.scopus.com/inward/record.url?eid=2-s2.0-85062841003&partnerID=MN8TOARS.
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  105. Castillo, Q.A.; Padrón, J.M.; Wojtas, L.; Keramane, M.; Germosén, E.A.. "Koanolide A, antiproliferative germacrane-type sesquiterpene lactone from Koanophyllon gibbosum". Tetrahedron Letters 60 25 (2019): 1640-1642. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065926503&partnerID=MN8TOARS.
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  106. Beer, M.F.; Bivona, A.E.; Alberti, A.S.; Cerny, N.; Reta, G.F.; Martín, V.S.; Padrón, J.M.; et al. "Preparation of sesquiterpene lactone derivatives: Cytotoxic activity and selectivity of action". Molecules 24 6 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85063585006&partnerID=MN8TOARS.
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  107. Sánchez-Tafolla, L.; Padrón, J.M.; Mendoza, G.; Luna-Rodríguez, M.; Fernández, J.J.; Norte, M.; Trigos, Á.. "Antiproliferative activity of biomass extract from Pseudomonas cedrina". Electronic Journal of Biotechnology 40 (2019): 40-44. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065042942&partnerID=MN8TOARS.
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  108. Brahmbhatt, G.C.; Sutariya, T.R.; Atara, H.D.; Parmar, N.J.; Gupta, V.K.; Lagunes, I.; Padrón, J.M.; Murumkar, P.R.; Yadav, M.R.. "New pyrazolyl-dibenzo[b,e][1,4]diazepinones: room temperature one-pot synthesis and biological evaluation". Molecular Diversity (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85066902075&partnerID=MN8TOARS.
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  109. Patel, D.M.; Sharma, M.G.; Vala, R.M.; Lagunes, I.; Puerta, A.; Padrón, J.M.; Rajani, D.P.; Patel, H.M.. "Hydroxyl alkyl ammonium ionic liquid assisted green and one-pot regioselective access to functionalized pyrazolodihydropyridine core and their pharmacological evaluation". Bioorganic Chemistry 86 (2019): 137-150. http://www.scopus.com/inward/record.url?eid=2-s2.0-85060495712&partnerID=MN8TOARS.
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  110. Filipovic, N.R.; Ristic, P.; Janjic, G.; Klisuric, O.; Puerta, A.; Padrón, J.M.; Donnard, M.; Gulea, M.; Todorovic, T.R.. "Silver-based monomer and coordination polymer with organic thiocyanate ligand: Structural, computational and antiproliferative activity study". Polyhedron 173 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85072584514&partnerID=MN8TOARS.
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  111. Padrón, José M.. "Naphthol-derived Betti bases as potential SLC6A14 blockers". Journal of Molecular and Clinical Medicine (2019): http://dx.doi.org/10.31083/j.jmcm.2019.02.7181.
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  112. Padrón, José M.. "Inhibition of glutamine metabolism as a therapeutic approach against pancreatic ductal adenocarcinoma". (2019):
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  113. Padrón, José M.. "Facts and myths of selective casein kinase 1e inhibition". Journal of Molecular and Clinical Medicine (2018): http://dx.doi.org/10.31083/j.jmcm.2018.04.401.
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  114. Padrón, José M.. "Bioprospecting of fungi with antiproliferative activity from the mangrove sediment of the Tampamachoco coastal lagoon, Veracruz, Mexico". Scientia Fungorum (2018): http://dx.doi.org/10.33885/sf.2018.48.1234.
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  115. Padrón, José M.. "A Small Molecule Tubulin Depolymerizing Agent Identi¿ed by a Phenotypic Drug Discovery Approach". Journal of Molecular and Clinical Medicine (2018): http://dx.doi.org/10.31083/j.jmcm.2018.02.003.
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  116. Padrón, José M.. "Differential mechanism of action of the CK1e inhibitor GSD0054". Journal of Molecular and Clinical Medicine (2018): http://dx.doi.org/10.31083/j.jmcm.2018.02.004.
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  117. Laura L. Romero-Hernández; Penélope Merino-Montiel; Socorro Meza-Reyes; José Luis Vega-Baez; Óscar López; José M. Padrón; Sara Montiel-Smith. "Synthesis of unprecedented steroidal spiro heterocycles as potential antiproliferative drugs". European Journal of Medicinal Chemistry 143 (2018): 21-32. https://doi.org/10.1016/j.ejmech.2017.10.063.
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  118. Begines, P.; Oliete, A.; López, Ó.; Maya, I.; Plata, G.B.; Padrón, J.M.; Fernández-Bolaños, J.G.. "Chalcogen-containing phenolics as antiproliferative agents". Future Medicinal Chemistry 10 3 (2018): 319-334. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041956361&partnerID=MN8TOARS.
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  119. Shnyreva, A.V.; Shnyreva, A.A.; Espinoza, C.; Padrón, J.M.; Trigos, Á.. "Antiproliferative activity and cytotoxicity of some medicinal wood-destroying mushrooms from Russia". International Journal of Medicinal Mushrooms 20 1 (2018): 1-11. http://www.scopus.com/inward/record.url?eid=2-s2.0-85044057437&partnerID=MN8TOARS.
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  120. Elshaflu, H.; Todorovic, T.R.; Nikolic, M.; Lolic, A.; Višnjevac, A.; Hagenow, S.; Padrón, J.M.; et al. "Selenazolyl-hydrazones as novel selective MAO inhibitors with antiproliferative and antioxidant activities: Experimental and In-silico studies". Frontiers in Chemistry 6 JUL (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85053084992&partnerID=MN8TOARS.
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  121. Luque-Agudo, V.; Padrón, J.M.; Román, E.; Serrano, J.A.; Gil, M.V.; V. Luque-Agudo; José M. Padrón; et al. "Antiproliferative activity of new 2-glyco-3-nitro-1,2-dihydroquinolines and quinolines synthesized under solventless conditions promoted by neutral alumina". New Journal of Chemistry 42 22 (2018): 18342-18347. http://www.scopus.com/inward/record.url?eid=2-s2.0-85056143649&partnerID=MN8TOARS.
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  122. Sharma, M.G.; Vala, R.M.; Patel, D.M.; Lagunes, I.; Fernandes, M.X.; Padrón, J.M.; Ramkumar, V.; Gardas, R.L.; Patel, H.M.. "Anti-Proliferative 1,4-Dihydropyridine and Pyridine Derivatives Synthesized through a Catalyst-Free, One-Pot Multi-Component Reaction". ChemistrySelect 3 43 (2018): 12163-12168. http://www.scopus.com/inward/record.url?eid=2-s2.0-85057018343&partnerID=MN8TOARS.
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  123. Castro, S.J.; García, M.E.; Padrón, J.M.; Navarro-Vázquez, A.; Gil, R.R.; Nicotra, V.E.. "Phytochemical Study of Senecio volckmannii Assisted by CASE-3D with Residual Dipolar Couplings and Isotropic 1H/13C NMR Chemical Shifts". Journal of Natural Products 81 11 (2018): 2329-2337. http://www.scopus.com/inward/record.url?eid=2-s2.0-85055654825&partnerID=MN8TOARS.
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  124. Valdomir, G.; Fernández, M.D.L.A.; Lagunes, I.; Padrón, J.I.; Martín, V.S.; Padrón, J.M.; Davyt, D.; et al. "Oxa/thiazole-tetrahydropyran triazole-linked hybrids with selective antiproliferative activity against human tumour cells". New Journal of Chemistry 42 16 (2018): 13784-13789. http://www.scopus.com/inward/record.url?eid=2-s2.0-85051416897&partnerID=MN8TOARS.
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  125. Morales-Amador, A.; de Vera, C.R.; Márquez-Fernández, O.; Daranas, A.H.; Padrón, J.M.; Fernández, J.J.; Souto, M.L.; Norte, M.. "Pinnatifidenyne-derived ethynyl oxirane acetogenins from laurencia viridis". Marine Drugs 16 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85040325981&partnerID=MN8TOARS.
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  126. Ingold, M.; Dapueto, R.; Victoria, S.; Galliusi, G.; Batthyàny, C.; Bollati-Fogolín, M.; Tejedor, D.; et al. "A green multicomponent synthesis of tocopherol analogues with antiproliferative activities". European Journal of Medicinal Chemistry 143 (2018): 1888-1902. http://www.scopus.com/inward/record.url?eid=2-s2.0-85033406746&partnerID=MN8TOARS.
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  127. Almada-Taylor, G.; Díaz-Rubio, L.; Salazar-Aranda, R.; de Torres, N.W.; Uranga-Solis, C.; Delgadillo-Rodríguez, J.; Ramos, M.A.; et al. "Biological activities of extracts from aerial parts of Salvia pachyphylla epling ex munz". Plants 7 4 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85060198000&partnerID=MN8TOARS.
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  128. Mendoza, Z.; Lorenzo-Luis, P.; Scalambra, F.; Padrón, J.M.; Romerosa, A.. "One Step Up in Antiproliferative Activity: The Ru-Zn Complex [RuCp(PPh3)2-µ-dmoPTA-1¿P:2¿2N,N'-ZnCl2](CF3SO3)". European Journal of Inorganic Chemistry 2018 43 (2018): 4684-4688. http://www.scopus.com/inward/record.url?eid=2-s2.0-85055727702&partnerID=MN8TOARS.
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  129. Martínez-Pascual R; Meza-Reyes S; Vega-Baez JL; Merino-Montiel P; Padrón JM; Mendoza Á; Montiel-Smith S. "Novel synthesis of steroidal oximes and lactams and their biological evaluation as antiproliferative agents.". (2017): http://europepmc.org/abstract/med/28396219.
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  130. Padrón, José M.. "Antiproliferative Activity and Effect on GABAA Receptors of Callitrisic Acid Derivatives". Planta Medica International Open (2017): http://dx.doi.org/10.1055/s-0043-119889.
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  131. Podolski-Renic A; Bankovic J; Dinic J; Ríos-Luci C; Fernandes MX; Ortega N; Kovacevic-Grujicic N; et al. "DTA0100, dual topoisomerase II and microtubule inhibitor, evades paclitaxel resistance in P-glycoprotein overexpressing cancer cells.". (2017): http://europepmc.org/abstract/med/28502672.
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  132. Labana BM; Brahmbhatt GC; Sutariya TR; Parmar NJ; Padrón JM; Kant R; Gupta VK. "Efficient synthesis and biological evaluation of new benzopyran-annulated pyrano[2,3-c]pyrazole derivatives.". (2017): http://europepmc.org/abstract/med/28293833.
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  133. Avanzo, R.E.; Padrón, J.M.; D'Accorso, N.B.; Fascio, M.L.. "Synthesis and in vitro antiproliferative activities of (5-aryl-1,2,4-oxadiazole-3-yl) methyl D-ribofuranosides". Bioorganic and Medicinal Chemistry Letters 27 16 (2017): 3674-3677. http://www.scopus.com/inward/record.url?eid=2-s2.0-85024120200&partnerID=MN8TOARS.
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  134. Gómez-Palomino, A.; Pellicena, M.; Krämer, K.; Romea, P.; Urpí, F.; Aullón, G.; Padrón, J.M.; et al. "Total synthesis of (+)-herboxidiene/GEX 1A". Organic and Biomolecular Chemistry 15 8 (2017): 1842-1862. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013927958&partnerID=MN8TOARS.
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  135. Casado-Sánchez, A.; Martín-Santos, C.; Padrón, J.M.; Mas-Ballesté, R.; Navarro-Ranninger, C.; Alemán, J.; Cabrera, S.. "Effect of electronic and steric properties of 8-substituted quinolines in gold(III) complexes: Synthesis, electrochemistry, stability, interactions and antiproliferative studies". Journal of Inorganic Biochemistry 174 (2017): 111-118. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021198502&partnerID=MN8TOARS.
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  136. Roldán-Peña, J.M.; Alejandre-Ramos, D.; López, Ó.; Maya, I.; Lagunes, I.; Padrón, J.M.; Peña-Altamira, L.E.; et al. "New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents". European Journal of Medicinal Chemistry 138 (2017): 761-773. http://www.scopus.com/inward/record.url?eid=2-s2.0-85024490154&partnerID=MN8TOARS.
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  137. Mendoza, Z.; Lorenzo-Luis, P.; Scalambra, F.; Padrón, J.M.; Romerosa, A.. "Enhancement of the antiproliferative activity of [RuCp(PPh3)2(dmoPTA-1¿P)]+: Via its coordination to one {CoCl2} unit: Synthesis, crystal structure and properties of [RuCp(PPh3)2-µ-dmoPTA-1¿P:2¿2 N, N '-CoCl2](OTf)·0.25H2O". Dalton Transactions 46 25 (2017): 8009-8012. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021749428&partnerID=MN8TOARS.
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  138. Zenaida Mendoza; Pablo Lorenzo-Luis; Franco Scalambra; José M. Padrón; Antonio Romerosa. "Enhancement of the antiproliferative activity of [RuCp(PPh3)2(dmoPTA-1¿P)]+via its coordination to one {CoCl2} unit: synthesis, crystal structure and properties of [RuCp(PPh3)2-µ-dmoPTA-1¿P:2¿2N,N'-CoCl2](OTf)·0.25H2O". Dalton Transactions 46 25 (2017): 8009-8012. https://doi.org/10.1039/C7DT01741C.
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  139. Alma Fuentes-Aguilar; Laura L. Romero-Hernández; Ailed Arenas-González; Penélope Merino-Montiel; Sara Montiel-Smith; Socorro Meza-Reyes; José Luis Vega-Báez; et al. "New selenosteroids as antiproliferative agents". Organic & Biomolecular Chemistry 15 23 (2017): 5041-5054. https://doi.org/10.1039/C7OB00458C.
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  140. Luque-Agudo, V.; Albarran-Velo, J.; Fernandez-Bolanos, J. G.; Lopez, O.; Light, M. E.; Padron, J. M.; Lagunes, I.; et al. "Synthesis and antiproliferative activity of sulfa-Michael adducts and thiochromenes derived from carbohydrates". New Journal of Chemistry 41 8 (2017): 3154-3162. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000401529600039&KeyUID=WOS:000401529600039.
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  141. Febles M; Montalvão S; Crespín GD; Norte M; Padrón JM; Tammela P; Fernández JJ; Daranas AH. "Synthesis and biological evaluation of crown ether acyl derivatives.". (2016): http://europepmc.org/abstract/med/27765506.
    10.1016/j.bmcl.2016.09.066
  142. Padrón, José; Couttolenc, A.; Espinoza, C.; Fernández, J.J.; Norte, M.; Plata, G.B.; Padrón, J.M.; Shnyreva, A.; Trigos, Á.. "Antiproliferative effect of extract from endophytic fungus Curvularia trifolii isolated from the "Veracruz Reef System" in Mexico.". Pharmaceutical Biology 54 8 (2016): 1392-1397. http://europepmc.org/abstract/med/27102888.
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  143. Padrón, José. "ent-Labdane Diterpenoids from the Aerial Parts of Eupatorium obtusissmum.". (2016): http://europepmc.org/abstract/med/27023255.
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  144. Cabrera-Benítez NE; Pérez-Roth E; Ramos-Nuez Á; Sologuren I; Padrón JM; Slutsky AS; Villar J. "Inhibition of endotoxin-induced airway epithelial cell injury by a novel family of pyrrol derivates.". (2016): http://europepmc.org/abstract/med/26999659.
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  145. Sánchez-Fernández EM; Gonçalves-Pereira R; Rísquez-Cuadro R; Plata GB; Padrón JM; García Fernández JM; Ortiz Mellet C. "Influence of the configurational pattern of sp(2)-iminosugar pseudo N-, S-, O- and C-glycosides on their glycoside inhibitory and antitumor properties.". (2016): http://europepmc.org/abstract/med/26850915.
    10.1016/j.carres.2016.01.006
  146. Ortega-Rivas, A.; Padrón, J.M.; Valladares, B.; Elsheikha, H.M.. "Acanthamoeba castellanii: A new high-throughput method for drug screening in vitro". Acta Tropica 164 (2016): 95-99. http://www.scopus.com/inward/record.url?eid=2-s2.0-84986917816&partnerID=MN8TOARS.
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  147. Silveira-Dorta, G.; Álvarez-Méndez, S.J.; Martín, V.S.; Padrón, J.M.. "One-pot synthesis of enantiomerically pure N-protected allylic amines from N-protected a-amino esters". Beilstein Journal of Organic Chemistry 12 (2016): 957-962. http://www.scopus.com/inward/record.url?eid=2-s2.0-84976351133&partnerID=MN8TOARS.
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  148. Barad, H.A.; Sutariya, T.R.; Brahmbhatt, G.C.; Parmar, N.J.; Lagunes, I.; Padrón, J.M.; Murumkar, P.; Sharma, M.K.; Yadav, M.R.. "A catalyst- and solvent-free multicomponent synthesis and docking study of some new antiproliferative: N 5-allyl-quinolylpyrido[2,3- b] [1,4]benzodiazepinone precursors". New Journal of Chemistry 40 6 (2016): 4931-4939. http://www.scopus.com/inward/record.url?eid=2-s2.0-84974622015&partnerID=MN8TOARS.
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  149. Arenas-González, A.; Mendez-Delgado, L.A.; Merino-Montiel, P.; Padrón, J.M.; Montiel-Smith, S.; Vega-Báez, J.L.; Meza- Reyes, S.. "Synthesis of monomeric and dimeric steroids containing [1,2,4]triazolo[1,5-a]pyrimidines". Steroids 116 (2016): 13-19. http://www.scopus.com/inward/record.url?eid=2-s2.0-84989853847&partnerID=MN8TOARS.
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  150. Luque-Agudo, V.; González Gutiérrez, A.M.; Lagunes, I.; López Galindo, F.; Padrón, J.M.; Román, E.; Serrano, J.A.; Gil, M.V.. "Synthesis and antiproliferative activity of peracetylated 2-amino-1,2-dideoxy-1-nitro-D-glycero-L-manno and D-glycero-D-talo heptitols". Bioorganic Chemistry 69 (2016): 71-76. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988943729&partnerID=MN8TOARS.
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  151. Espinoza, C.; Couttolenc, A.; Fernández, J.J.; Norte, M.; Plata, G.B.; Padrón, J.M.; Shnyreva, A.; Trigos, Á.. "Brefeldin-a: An antiproliferative metabolite of the fungus curvularia trifolii collected from the veracruz coral reef system, Mexico". Journal of the Mexican Chemical Society 60 2 (2016): 79-82. http://www.scopus.com/inward/record.url?eid=2-s2.0-84987746799&partnerID=MN8TOARS.
  152. Mendoza, Z.; Lorenzo-Luis, P.; Serrano-Ruiz, M.; Martín-Batista, E.; Padrón, J.M.; Scalambra, F.; Romerosa, A.. "Synthesis and Antiproliferative Activity of [RuCp(PPh3)2(HdmoPTA)](OSO2CF3)2 (HdmoPTA = 3,7-H-3,7-Dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane)". Inorganic Chemistry 55 16 (2016): 7820-7822. http://www.scopus.com/inward/record.url?eid=2-s2.0-84982151658&partnerID=MN8TOARS.
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  153. Olsen, J.I.; Plata, G.B.; Padrón, J.M.; López, Ó.; Bols, M.; Fernández-Bolaños, J.G.. "Selenoureido-iminosugars: A new family of multitarget drugs". European Journal of Medicinal Chemistry 123 (2016): 155-160. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979573555&partnerID=MN8TOARS.
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  157. Nieto, D.; Bruña, S.; González-Vadillo, A.M.; Perles, J.; Carrillo-Hermosilla, F.; Antiñolo, A.; Padrón, J.M.; Plata, G.B.; Cuadrado, I.. "Catalytically Generated Ferrocene-Containing Guanidines as Efficient Precursors for New Redox-Active Heterometallic Platinum(II) Complexes with Anticancer Activity". Organometallics 34 22 (2015): 5407-5417. http://www.scopus.com/inward/record.url?eid=2-s2.0-84948669073&partnerID=MN8TOARS.
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  158. Silveira-Dorta, G.; Sousa, I.J.; Fernandes, M.X.; Martín, V.S.; Padrón, J.M.. "Synthesis and identification of unprecedented selective inhibitors of CK1e". European Journal of Medicinal Chemistry 96 (2015): 308-317. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928012550&partnerID=MN8TOARS.
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  161. Frías, M.; Padrõn, J.M.; Alemán, J.. "Dienamine and friedel-crafts one-pot synthesis, and antitumor evaluation of diheteroarylalkanals". Chemistry - A European Journal 21 22 (2015): 8237-8241. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929378304&partnerID=MN8TOARS.
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  162. Urosa, A.; Marcos, I.S.; Díez, D.; Padrón, J.M.; Basabe, P.. "Synthesis of Luffarin L and 16- epi -Luffarin L Using a Temporary Silicon-Tethered Ring-Closing Metathesis Reaction". Journal of Organic Chemistry 80 12 (2015): 6447-6455. http://www.scopus.com/inward/record.url?eid=2-s2.0-84934948334&partnerID=MN8TOARS.
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  163. Calcatierra, Veronica; Lopez, Oscar; Fernandez-Bolanos, Jose G; Plata, Gabriela B; Padron, Jose M. "Phenolic thio- and selenosemicarbazones as multi-target drugs.". European journal of medicinal chemistry 94 (2015): 63-72. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:25752525&KeyUID=MEDLINE:25752525.
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  164. Sutariya, T. R.; Labana, B. M.; Parmar, N. J.; Kant, R.; Gupta, V. K.; Plata, G. B.; Padron, J. M.. "Efficient synthesis of some new antiproliferative N-fused indoles and isoquinolines via 1,3-dipolar cycloaddition reaction in an ionic liquid". New Journal of Chemistry 39 4 (2015): 2657-2668. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000352543800042&KeyUID=WOS:000352543800042.
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  165. Martín, M.; Urosa, A.; Marcos, I.S.; Díez, D.; Padrón, J.M.; Basabe, P.. "Biomimetic synthesis of two salmahyrtisanes: Salmahyrtisol A and hippospongide A". Journal of Organic Chemistry 80 9 (2015): 4566-4572. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928911570&partnerID=MN8TOARS.
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  166. Cedrón JC; Ravelo ÁG; León LG; Padrón JM; Estévez-Braun A. "Antiproliferative and Structure Activity Relationships of Amaryllidaceae Alkaloids.". (2015): http://europepmc.org/abstract/med/26263960.
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  168. Garcia, Manuela E.; Nicotra, Viviana E.; Oberti, Juan C.; Rios-Luci, Carla; Leon, Leticia G.; Marler, Laura; Li, Guannan; et al. "Antiproliferative and quinone reductase-inducing activities of withanolides derivatives". European Journal of Medicinal Chemistry 82 (2014): 68-81. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000339039100006&KeyUID=WOS:000339039100006.
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  169. Carballo, Ruben M.; Leon, Leticia G.; Quijano-Quinones, Ramiro F.; Mena-Rejon, Gonzalo J.; Martin, Victor S.; Padron, Jose M.; Padron, Juan I.; et al. "Antiproliferative Evaluation of N-sulfonyl-2-alkyl-six Membered Azacycles. A QSAR Study". Medicinal Chemistry 10 6 (2014): 571-579. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000340643500004&KeyUID=WOS:000340643500004.
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  170. Valdomir, Cuillermo; Padron, Juan I.; Padron, Jose M.; Martin, Vctor S.; Davyt, Danilo. "Oxazole/Thiazole and Triazole Hybrids Based on alpha-Amino Acids". Synthesis-Stuttgart 46 18 (2014): 2451-2462. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000342565800007&KeyUID=WOS:000342565800007.
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  171. Duchowicz, Pablo R.; Bennardi, Daniel O.; Bacelo, Daniel E.; Bonifazi, Evelyn L.; Rios-Luci, Carla; Padron, Jose M.; Burton, Gerardo; Misico, Rosana I.. "QSAR on antiproliferative naphthoquinones based on a conformation-independent approach". European Journal of Medicinal Chemistry 77 2 (2014): 176-184. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000335874800020&KeyUID=WOS:000335874800020.
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  172. Silveira-Dorta, Gaston; Donadel, Osvaldo J.; Martin, Victor S.; Padron, Jose M.. "Direct Stereoselective Synthesis of Enantiomerically Pure anti-beta-Amino Alcohols". Journal of Organic Chemistry 79 15 (2014): 6775-6782. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000339983300003&KeyUID=WOS:000339983300003.
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  173. Silveira-Dorta, Gaston; Martin, Victor S.; Padron, Jose M.. "Direct Synthesis of Polybenzylated Glutamic Acid Monoesters: Disambiguation of N,N-Dibenzylglutamic Acid alpha- and gamma-Benzyl Esters". Synlett 25 15 (2014): 2166-2170. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000342570700015&KeyUID=WOS:000342570700015.
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  174. Trigos A; Espinoza C; Martínez M; Márquez O; León LG; Padrón JM; Norted M; et al. "Antiproliferative activity of epi-cercosporin in human solid tumor cell lines.". Natural Product Communications 8 2 (2013): 187-189. http://europepmc.org/abstract/med/23513725.
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  175. Reta, Guillermo F.; Chiaramello, Alejandra I.; Garcia, Celina; Leon, Leticia G.; Martin, Victor S.; Padron, Jose M.; Tonn, Carlos E.; Donadel, Osvaldo J.. "Derivatives of grindelic acid: From a non-active natural diterpene to synthetic antitumor derivatives". European Journal of Medicinal Chemistry 67 (2013): 28-38.
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  176. del Solar, Virginia; Quinones-Lombrana, Adolfo; Cabrera, Silvia; Padron, Jose M.; Rios-Luci, Carla; Alvarez-Valdes, Amparo; Navarro-Ranninger, Carmen; Aleman, Jose. "Expanding the synthesis of new trans-sulfonamide platinum complexes: Cytotoxicity, SAR, fluorescent cell assays and stability studies". Journal of Inorganic Biochemistry 127 (2013): 128-140.
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  177. Cordova-Guerrero, I.; San Andres, Lucia; Leal-Orozco, Alma E.; Padron, Jose M.; Cornejo-Bravo, J. M.; Leon, Francisco. "New strategy toward the diverted synthesis of oxidized abietane diterpenes via oxidation of 6,7-dehydroferruginol methyl ether with dimethyldioxirane". Tetrahedron Letters 54 33 (2013): 4479-4482.
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  178. Martin Santos, Cecilia; Cabrera, Silvia; Rios-Luci, Carla; Padron, Jose M.; Lopez Solera, Isabel; Quiroga, Adoracion G.; Medrano, Maria A.; Navarro-Ranninger, Carmen; Aleman, Jose. "Novel clioquinol and its analogous platinum complexes: importance, role of the halogen substitution and the hydroxyl group of the ligand". Dalton Transactions 42 37 (2013): 13343-13348.
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  179. Sousa, Ines J.; Padron, Jose M.; Fernandes, Miguel X.. "Generation of artificial neural networks models in anticancer study". Neural Computing & Applications 23 3-4 (2013): 577-582.
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  180. Silveira-Dorta, Gaston; Sousa, Ines J.; Rios-Luci, Carla; Martin, Victor S.; Fernandes, Miguel X.; Padron, Jose M.. "Molecular docking studies of the interaction between propargylic enol ethers and human DNA topoisomerase II alpha". Bioorganic & Medicinal Chemistry Letters 23 19 (2013): 5382-5384.
    10.1016/j.bmcl.2013.07.055
  181. Serrano-Ruiz, Manuel; Manuel Aguilera-Saez, Luis; Lorenzo-Luis, Pablo; Padron, Jose M.; Romerosa, Antonio. "Synthesis and antiproliferative activity of the heterobimetallic complexes [RuClCp(PPh3)-mu-dmoPTA-1 kappa P:2 kappa N-2,N '-MCl2] (M = Co, Ni, Zn; dmoPTA=3,7-dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane)". Dalton Transactions 42 31 (2013): 11212-11219.
    10.1039/c3dt50829c
  182. Karpaviciene, Ieva; Cikotiene, Inga; Padron, Jose M. "Synthesis and antiproliferative activity of alpha-branched alpha,beta-unsaturated ketones.". European journal of medicinal chemistry 70 (2013): 568-78.
    10.1016/j.ejmech.2013.10.041
  183. Reta GF; Tonn CE; Ríos-Luci C; León LG; Pérez-Roth E; Padrón JM; Donadel OJ; et al. "Cytotoxic bioactivity of some phenylpropanoic acid derivatives.". Natural Product Communications 7 10 (2012): 1341-1346. http://europepmc.org/abstract/med/23157005.
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  184. Rios-Luci, Carla; Bonifazi, Evelyn L.; Leon, Leticia G.; Montero, Juan C.; Burton, Gerardo; Pandiella, Atanasio; Misico, Rosana I.; Padron, Jose M.. "beta-Lapachone analogs with enhanced antiproliferative activity". European Journal of Medicinal Chemistry 53 (2012): 264-274.
    10.1016/j.ejmech.2012.04.008
  185. Cabrera-Benitez, Nuria E.; Perez-Roth, Eduardo; Casula, Milena; Ramos-Nuez, Angela; Rios-Luci, Carla; Rodriguez-Gallego, Carlos; Sologuren, Ithaisa; et al. "Anti-Inflammatory Activity of a Novel Family of Aryl Ureas Compounds in an Endotoxin-Induced Airway Epithelial Cell Injury Model". Plos One 7 11 (2012):
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  186. Garcia, Manuela E.; Barboza, Gloria E.; Oberti, Juan C.; Rios-Luci, Carla; Padron, Jose M.; Nicotra, Viviana E.; Estevez-Braun, Ana; Ravelo, Angel G.. "Antiproliferative activity of withanolide derivatives from Jaborosa cabrerae and Jaborosa reflexa. Chemotaxonomic considerations". Phytochemistry 76 (2012): 150-157.
    10.1016/j.phytochem.2011.12.018
  187. Bordón, E.; León, L.G.; Ríos-Luci, C.; Lara, P.C.; Padrón, J.M.. "In vitro synergistic interaction between DTA0100 and radiation in human cancercell lines". Anti-Cancer Agents in Medicinal Chemistry 12 8 (2012): 988-993. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866413012&partnerID=MN8TOARS.
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  188. Nieto, Daniel; Gonzalez-Vadillo, Ana M.; Bruna, Sonia; Pastor, Cesar J.; Rios-Luci, Carla; Leon, Leticia G.; Padron, Jose M.; Navarro-Ranninger, Carmen; Cuadrado, Isabel. "Heterometallic platinum(II) compounds with beta-aminoethylferrocenes: synthesis, electrochemical behaviour and anticancer activity". Dalton Transactions 41 2 (2012): 432-441.
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  189. Padrón, José M.. "Reactivity and biological properties of a series of cytotoxic PtI2(amine)2 complexes, either cis or trans configured". Inorganic Chemistry 51 3 (2012): 1717-1726. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856689931&partnerID=MN8TOARS.
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  190. "Abietane diterpenoids from some salvia species: Chemical transformations and antiproliferative activity". Planta Medica (2012): https://publons.com/wos-op/publon/19048554/.
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  191. León LG; Giovannetti E; Alecci C; Giancola F; Funel N; Zucali P; Peters GJ; et al. "Antiproliferative effects of novel aliphatic acetogenin analogs against aggressive solid tumor cell lines.". In Vivo 25 2 (2011): 203-207. http://europepmc.org/abstract/med/21471536.
  192. Aleman, Jose; del Solar, Virginia; Alvarez-Valdes, Amparo; Rios-Luci, Carla; Padron, Jose M.; Navarro-Ranninger, Carmen. "Novel N-sulfonamide trans-platinum complexes: synthesis, reactivity and in vitro evaluation". Medchemcomm 2 8 (2011): 789-793.
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  193. Esteve, Judit; Lorente, Adriana; Romea, Pedro; Urpi, Felix; Rios-Luci, Carla; Padron, Jose M.. "Synthesis and Biological Evaluation of 1-Deoxy-5-hydroxysphingosine Derivatives". European Journal of Organic Chemistry 5 (2011): 960-967.
    10.1002/ejoc.201001268
  194. Rios-Luci, Carla; Leon, Leticia G.; Mena-Cruz, Adrian; Perez-Roth, Eduardo; Lorenzo-Luis, Pablo; Romerosa, Antonio; Padron, Jose M.. "Antiproliferative activity of dmoPTA-Ru(II) complexes against human solid tumor cells". Bioorganic & Medicinal Chemistry Letters 21 15 (2011): 4568-4571.
    10.1016/j.bmcl.2011.05.116
  195. Rios-Luci, Carla; Dominguez-Kelly, Raquel; Leon, Leticia G.; Diaz-Rodriguez, Elena; Freire, Raimundo; Pandiella, Atanasio; Cikotiene, Inga; Padron, Jose M.. "A modular approach to trim cellular targets in anticancer drug discovery". Bioorganic & Medicinal Chemistry Letters 21 22 (2011): 6641-6645.
    10.1016/j.bmcl.2011.09.069
  196. Leon, Leticia G.; Giovannetti, Elisa; Alecci, Claudia; Giancola, Fiorella; Funel, Niccola; Zucali, Paolo; Peters, Godefridus J.; Manuel Padron, Jose. "Cytotoxicity of Aliphatic Acetogenin Analogs against two of the most Aggressive Solid Tumors". The FASEB Journal (2011): https://publons.com/wos-op/publon/11842720/.
  197. Rios-Luci, Carla P.; Leon, Leticia G.; Perez-Roth, Eduardo; Padron, Jose M.. "Endoreduplication induced by a novel family of DNA Topoisomerase II inhibitors". The FASEB Journal (2011): https://publons.com/wos-op/publon/28244206/.
  198. José M. Padrón. "Antimicrobial Drug Resistance (2 volumes). Edited by Douglas L. Mayers.". ChemMedChem 5 6 (2010): 960-961. http://dx.doi.org/10.1002/cmdc.201000025.
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  199. Rudys, Simonas; Rios-Luci, Carla; Perez-Roth, Eduardo; Cikotiene, Inga; Padron, Jose M.. "Antiproliferative activity of novel benzo b 1,6 naphthyridines in human solid tumor cell lines". Bioorganic & Medicinal Chemistry Letters 20 5 (2010): 1504-1506.
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  200. Bonifazi, Evelyn L.; Rios-Luci, Carla; Leon, Leticia G.; Burton, Gerardo; Padron, Jose M.; Misico, Rosana I.. "Antiproliferative activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol". Bioorganic & Medicinal Chemistry 18 7 (2010): 2621-2630.
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  201. Messori, Luigi; Casini, Angela; Gabbiani, Chiara; Michelucci, Elena; Cubo, Leticia; Rios-Luci, Carla; Padron, Jose M.; Navarro-Ranninger, Carmen; Quiroga, Adoracion G.. "Cytotoxic Profile and Peculiar Reactivity with Biomolecules of a Novel "Rule-Breaker" Iodidoplatinum(II) Complex". Acs Medicinal Chemistry Letters 1 8 (2010): 381-385.
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  202. Machin, Ruben P.; Veleiro, Adriana S.; Nicotra, Viviana E.; Oberti, Juan C.; Padron, Jose M.. "Antiproliferative Activity of Withanolides against Human Breast Cancer Cell Lines". Journal of Natural Products 73 5 (2010): 966-968.
    10.1021/np9006734
  203. Tereza Rojo de Almeida, Maria; Rios-Luci, Carla; Padron, Jose M.; Palermo, Jorge A.. "Antiproliferative terpenoids and alkaloids from the roots of Maytenus vitis-idaea and Maytenus spinosa". Phytochemistry 71 14-15 (2010): 1741-1748.
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  204. Garcia, Celina; Leon, Leticia G.; Pungitore, Carlos R.; Rios-Luci, Carla; Daranas, Antonio H.; Montero, Juan C.; Pandiella, Atanasio; et al. "Enhancement of antiproliferative activity by molecular simplification of catalpol". Bioorganic & Medicinal Chemistry 18 7 (2010): 2515-2523.
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  205. Leon, Leticia G.; Rios-Luci, Carla; Tejedor, David; Perez-Roth, Eduardo; Montero, Juan C.; Pandiella, Atanasio; Garcia-Tellado, Fernando; Padron, Jose M.. "Mitotic Arrest Induced by a Novel Family of DNA Topoisomerase II Inhibitors". Journal of Medicinal Chemistry 53 9 (2010): 3835-3839.
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  206. Rios Luci, Carla Patricia; Leon, Leticia G.; Montero, Juan C.; Tejedor, David; Pandiella, Atanasio; Garcia-Tellado, Fernando; Padron, Jose M.. "Mitotic arrest induced by propargylic enol ethers derivatives". The FASEB Journal (2010): https://publons.com/wos-op/publon/28244207/.
  207. José G. Napolitano; Manuel Norte; José M. Padrón; José J. Fernández; Antonio Hernández Daranas; Napolitano, J.G.; Norte, M.; et al. "Belizeanolide, a Cytotoxic Macrolide from the Dinoflagellate Prorocentrum belizeanum". Angew. Chem. 121 4 (2009): 810-813. http://dx.doi.org/10.1002/ange.200804023.
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  208. Pudziuvelyte, Erika; Rios-Luci, Carla; Leon, Leticia G.; Cikotiene, Inga; Padron, Jose M.. "Synthesis and antiproliferative activity of 2,4-disubstituted 6-aryl-7H-pyrrolo 3,2-d pyrimidin-7-one 5-oxides". Bioorganic & Medicinal Chemistry 17 14 (2009): 4955-4960.
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  209. Leon, Leticia G.; Donadel, Osvaldo J.; Tonn, Carlos E.; Padron, Jose M.. "Tessaric acid derivatives induce G(2)/M cell cycle arrest in human solid tumor cell lines". Bioorganic & Medicinal Chemistry 17 17 (2009): 6251-6256.
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  210. Hubeek, I.; Comijn, E.M.; Van der Wilt, C.L.; Merriman, R.L.; Padron, J.M.; Kaspers, G.J.L.; Peters, G.J.. "CI-994 (N-acetyl-dinaline) in combination with conventional anti-cancer agents is effective against acute myeloid leukemia in vitro and in vivo". Oncology Reports 19 6 (2008): 1517-1523. http://www.scopus.com/inward/record.url?eid=2-s2.0-48849094081&partnerID=MN8TOARS.
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  211. Leon, Leticia G.; Machin, Ruben P.; Rodriguez, Carmen M.; Ravelo, Jose L.; Martin, Victor S.; Padron, Jose M.. "gamma-lactones alpha,beta- and beta,gamma-fused to carbocycles as novel antiproliferative drugs". Bioorganic & Medicinal Chemistry Letters 18 19 (2008): 5171-5173.
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  212. Leon, Leticia G.; Carballo, Ruben M.; Vega-Hernandez, Maria C.; Miranda, Pedro O.; Martin, Victor S.; Padron, Juan I.; Padron, Jose M.. "ß'-Hydroxy-a,ß-Unsaturated Ketones: A new pharmacophore for the design of anticancer drugs. Part 2". Chemmedchem 3 11 (2008): 1740-1747.
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  213. "In vitro antiproliferative activity of Xanthones and Guttiferones from Securidaca spp". Planta Medica (2008): https://publons.com/wos-op/publon/11927107/.
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  214. Sousa, I; Kairys, V; Padron, J. M.; Fernandes, M. X.. "Identification of molecular targets in anti-cancer therapy using protein-ligand docking". Planta Medica (2008): https://publons.com/wos-op/publon/19048555/.
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  215. Bijnsdorp IV; Comijn EM; Padron JM; Gmeiner WH; Peters GJ. "Mechanisms of action of FdUMP[10]: metabolite activation and thymidylate synthase inhibition.". Oncology reports (2007): http://europepmc.org/abstract/med/17549381.
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  216. I. Cordova; L. G. Leon; F. Leon; L. San Andres; J. G. Luis; J. M. Padron. "Synthesis and Antiproliferative Activity of Novel Sugiol ß-Amino Alcohol Analogues.". ChemInform 38 12 (2007): http://dx.doi.org/10.1002/chin.200712191.
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  217. Bijnsdorp, I.V.; Comijn, E.M.; Padron, J.M.; Gmeiner, W.H.; Peters, G.J.; Bijnsdorp, I. V.; Comijn, E. M.; et al. "Mechanisms of action of FdUMP[10]: Metabolite activation and thymidylate synthase inhibition". Oncology Reports 18 1 (2007): 287-291. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548017882&partnerID=MN8TOARS.
    10.3892/or.18.1.287
  218. Pungitore, C.R.; Padrón, J.M.; Leon, L.G.; García, C.; Ciuffo, G.M.; Martin, V.S.; Tonn, C.E.; et al. "Inhibition of DNA topoisomerase I and growth inhibition of human cancer cell lines by an oleanane from Junellia aspera (Verbenaceae)". Cellular and Molecular Biology 53 3 (2007): 13-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-84965098356&partnerID=MN8TOARS.
    10.1170/T791
  219. Leon, Leticia G.; Carballo, Ruben M.; Vega-Hernandez, Maria C.; Martin, Victor S.; Padron, Juan I.; Padron, Jose M.. "Antiproliferative activity of 2-alkyl-4-halopiperidines and 2-alkyl-4-halo-1,2,5,6-tetrahydropyridines in solid tumor cell lines". Bioorganic & Medicinal Chemistry Letters 17 10 (2007): 2681-2684.
    10.1016/j.bmcl.2007.03.010
  220. Leon, Leticia G.; Miranda, Pedro O.; Martin, Victor S.; Padron, Juan I.; Padron, Jose M.. "Antiproliferative activity of 4-chloro-5,6-dihydro-2H-pyrans. Part 2: Enhancement of drug cytotoxicity". Bioorganic & Medicinal Chemistry Letters 17 11 (2007): 3087-3090.
    10.1016/j.bmcl.2007.03.045
  221. Sanhueza, Carlos A.; Mayato, Carlos; Machin, Ruben P.; Padron, Jose M.; Dorta, Rosa L.; Vazquez, Jesus T.. "Cytotoxic effects of C-glycosides in HOS and HeLa cell lines". Bioorganic & Medicinal Chemistry Letters 17 13 (2007): 3676-3681.
    10.1016/j.bmcl.2007.04.060
  222. Pungitore, Carlos R.; Leon, Leticia G.; Garcia, Celina; Martin, Victor S.; Tonn, Carlos E.; Padron, Jose M.. "Novel antiproliferative analogs of the Taq DNA polymerase inhibitor catalpol". Bioorganic & Medicinal Chemistry Letters 17 5 (2007): 1332-1335.
    10.1016/j.bmcl.2006.11.086
  223. Donadel, Osvaldo J.; Martin, Tomas; Martin, Victor S.; Padron, Jose M.. "Samarium(II) promoted stereoselective synthesis of antiproliferative cis-beta-alkoxy-gamma-alkyl-gamma-lactones". Bioorganic & Medicinal Chemistry Letters 17 1 (2007): 18-21.
    10.1016/j.bmcl.2006.10.005
  224. Carrillo, R.; León, L.G.; Martín, T.; Martín, V.S.; Padrón, J.M.. "Synthesis and antiproliferative activity of (2R,3R)-disubstituted tetrahydropyrans. Part 2: Effect of side chain homologation". Bioorganic and Medicinal Chemistry Letters 17 3 (2007): 780-783. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846214455&partnerID=MN8TOARS.
    10.1016/j.bmcl.2006.10.066
  225. "Isolation, chemical transformations, and antiproliferative activity against human cancer cell lines of abietane cliterpenes from two Mexican Salvia species". Planta Medica (2007): https://publons.com/wos-op/publon/19048556/.
  226. Jose M. Padron; Pedro O. Miranda; Juan I. Padron; Victor S. Martin. "ß'-Hydroxy-a,ß-Unsaturated Ketones: A New Pharmacophore for the Design of Anticancer Drugs.". ChemInform 37 28 (2006): http://dx.doi.org/10.1002/chin.200628059.
    10.1002/chin.200628059
  227. Miranda, Pedro O.; Padron, Jose M.; Padron, Juan I.; Villar, Jesus; Martin, Victor S.. "Prins-type synthesis and SAR study of cytotoxic alkyl chloro dihydropyrans". Chemmedchem 1 3 (2006): 323-329.
    10.1002/cmdc.200500057
  228. Padron, J. M.. "Sphingolipids in anticancer therapy". Current Medicinal Chemistry 13 7 (2006): 755-770.
    10.2174/092986706776055553
  229. Crisostomo, F. R. P.; Carrillo, R.; Leon, L. G.; Martin, T.; Padron, J. M.; Martin, V. S.. "Molecular simplification in bioactive molecules: Formal synthesis of (+)-muconin". Journal of Organic Chemistry 71 6 (2006): 2339-2345.
    10.1021/jo0524674
  230. Miranda, P. O.; Leon, L. G.; Martin, V. S.; Padron, J. I.; Padron, J. M.; Pedro O. Miranda; Leticia G. Leon; et al. "One-pot synthesis and SAR study of cis-2,6-dialkyl-4-chloro-tetrahydropyrans". Bioorganic & Medicinal Chemistry Letters 16 12 (2006): 3135-3138. http://dx.doi.org/10.1002/chin.200637123.
    10.1016/j.bmcl.2006.03.064
  231. Cordova, I.; Leon, L. G.; Leon, F.; San Andres, L.; Luis, J. G.; Padron, J. M.. "Synthesis and antiproliferative activity of novel sugiol beta-amino alcohol analogs". European Journal of Medicinal Chemistry 41 11 (2006): 1327-1332.
    10.1016/j.ejmech.2006.06.001
  232. Crisostomo, F. R. P.; Padron, J. M.; Martin, T.; Villar, J.; Martin, V. S.. "A short and efficient enantiomeric synthesis of antitumor fused tetrahydrofurans". European Journal of Organic Chemistry 8 (2006): 1910-1916.
    10.1002/ejoc.200500842
  233. Padron, J. M.; Peters, G. J.. "Cytotoxicity of sphingoid marine compound analogs in mono- and multilayered solid tumor cell cultures". Investigational New Drugs 24 3 (2006): 195-202.
    10.1007/s10637-005-3691-5
  234. Padron, J. M.; Donadel, O. J.; Leon, L. G.; Martin, T.; Martin, V. S.. "Enhancement of drug cytotoxicity by silicon containing groups". Letters in Drug Design & Discovery 3 1 (2006): 29-34.
    10.2174/157018006775240944
  235. Guerrero, Iva N. C.; Andres, Lucia S.; Leon, Leticia G.; Machin, Ruben P.; Padron, Jose M.; Luis, Javier G.; Delgadillo, Jose. "Abietane diterpenoids from Salvia pachyphylla and S-Clevelandii with cytotoxic activity against human cancer cell lines". Journal of Natural Products 69 12 (2006): 1803-1805.
    10.1021/np060279i
  236. Padrón, J.M.; Miranda, P.O.; Padrón, J.I.; Martín, V.S.. "ß'-Hydroxy-a,ß-unsaturated ketones: A new pharmacophore for the design of anticancer drugs". Bioorganic and Medicinal Chemistry Letters 16 8 (2006): 2266-2269. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644807115&partnerID=MN8TOARS.
    10.1016/j.bmcl.2006.01.023
  237. Carrillo, R.; León, L.G.; Martín, T.; Martín, V.S.; Padrón, J.M.. "Synthesis and antiproliferative activity of (2R,3R)-disubstituted tetrahydropyrans". Bioorganic and Medicinal Chemistry Letters 16 23 (2006): 6135-6138. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750531635&partnerID=MN8TOARS.
    10.1016/j.bmcl.2006.08.094
  238. Padron, J. M.; Tejedor, D.; Santos-Exposito, A.; Garcia-Tellado, F.; Martin, V. S.; Villar, J.. "Antiproliferative activity in HL60 cells by tetrasubstituted pyrroles: a structure-activity relationship study". Bioorganic & Medicinal Chemistry Letters 15 10 (2005): 2487-2490.
    10.1016/j.bmcl.2005.03.069
  239. Padron, J. M.; Tejedor, D.; Santos-Exposito, A.; Garcia-Tellado, F.; Villar, J.; Martin, V. S.. "Synthesis and anti-breast cancer activity of tetrasubstituted pyrrole derivatives". Letters in Drug Design & Discovery 2 7 (2005): 529-532.
    10.2174/157018005774479122
  240. Donadel, O. J.; Martin, T.; Martin, V. S.; Villar, J.; Padron, J. M.. "The tert-butyl dimethyl silyl group as an enhancer of drug cytotoxicity against human tumor cells". Bioorganic & Medicinal Chemistry Letters 15 15 (2005): 3536-3539.
    10.1016/j.bmcl.2005.05.126
  241. "Modulation of cytotoxicity by the tert-butyl dimethyl silyl group". Annals of Oncology (2005): https://publons.com/wos-op/publon/5550727/.
  242. "Development of new anticancer drugs from secondary metabolites of marine origin". Journal of Biotechnology (2005): https://publons.com/wos-op/publon/5550722/.
  243. "Secondary metabolites of marine origin in the development of novel anticancer agents.". Clinical Cancer Research (2005): https://publons.com/wos-op/publon/5550719/.
  244. "Induction of apoptosis by fused tetrahydrofuranes". Annals of Oncology (2005): https://publons.com/wos-op/publon/19048558/.
  245. Al-Madhoun, A. S.; van der Wilt, C. L.; Loves, W. J. P.; Padron, J. M.; Eriksson, S.; Talianidis, I.; Peters, G. J.. "Detection of an alternatively spliced form of deoxycytidine kinase mRNA in the 2 '-2 '-difluorodeoxycytidine (gemcitabine)-resistant human ovarian cancer cell line AG6000". Biochemical Pharmacology 68 4 (2004): 601-609.
    10.1016/j.bcp.2004.05.007
  246. "Inhibition of the activity of the native ¿-aminobutyric acidA receptor by metabolites of thyroid hormones: correlations with molecular modeling studies". Brain Research (2004): https://publons.com/wos-op/publon/4260544/.
    10.1016/J.BRAINRES.2003.12.043
  247. Lambers, M.; Beijer, F. H.; Padron, J. M.; Toth, I.; de Vries, J. G.. "Highly selective hydroformylation of the cinchona alkaloids". Journal of Organic Chemistry 67 14 (2002): 5022-5024.
    10.1021/jo0255173
  248. Schmieder-van de Vondervoort, L.; Bouttemy, S.; Padron, J. M.; Le Bras, J.; Muzart, J.; Alsters, P. L.. "Chromium catalyzed oxidation of (homo-)allylic and (homo-)propargylic alcohols with sodium periodate to ketones or carboxylic acids". Synlett 2 (2002): 243-246.
    UNSP 1437-2096,E;2002,0,02,0243,0246,ftx,en;G33001ST.pd
  249. Baragaña, B.; Blackburn, A.G.; Breccia, P.; Davis, A.P.; De Mendoza, J.; Padrón-Carrillo, J.M.; Prados, P.; et al. "Enantioselective transport by a steroidal guanidinium receptor". Chemistry - A European Journal 8 13 (2002): 2931-2936. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037007877&partnerID=MN8TOARS.
    10.1002/1521-3765(20020703)8:13<2931::AID-CHEM2931>3.0.CO;2-H
  250. Kokotos, G.; Constantinou-Kokotou, V.; Padrón, J.M.; Peters, G.J.; Padron, J. M.; Peters, G. J.. "Synthesis and in vitro cytotoxicity of novel long chain busulphan analogues". Bioorganic and Medicinal Chemistry Letters 11 6 (2001): 861-863. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035953059&partnerID=MN8TOARS.
    10.1016/S0960-894X(01)00084-1
  251. Markidis, T.; Padron, J.M.; Martin, V.S.; Peters, G.J.; Kokotos, G.. "Synthesis and in vitro cytotoxicity of long chain 2-amino alcohols and 1,2-diamines". Anticancer Research 21 4 A (2001): 2835-2839. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035149524&partnerID=MN8TOARS.
  252. "Chromium catalyzed oxidations of alcohols with sodium periodate.". Abstracts of Papers of the American Chemical Society (2001): https://publons.com/wos-op/publon/19048559/.
  253. Padrón, J.M.; Van Der Wilt, C.L.; Smid, K.; Smitskamp-Wilms, E.; Backus, H.H.J.; Pizao, P.E.; Giaccone, G.; et al. "The multilayered postconfluent cell culture as a model for drug screening". Critical Reviews in Oncology/Hematology 36 2-3 (2000): 141-157. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033795717&partnerID=MN8TOARS.
    10.1016/S1040-8428(00)00083-4
  254. Backus, H.H.J.; Pinedo, H.M.; Wouters, D.; Padrón, J.M.; Molders, N.; Van Der Wilt, C.L.; Van Groeningen, C.J.; et al. "Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates". International Journal of Cancer 87 6 (2000): 771-778. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033845077&partnerID=MN8TOARS.
    10.1002/1097-0215(20000915)87:6<771::AID-IJC2>3.0.CO;2-V
  255. Padrón, J.M.; Martin, V.S.; Hadjipavlou-Litina, D.; Noula, C.; Constantinou-Kokotou, V.; Peters, G.J.; Kokotos, G.; et al. "Synthesis, in vitro cytotoxicity and in vivo anti-inflammatory activity of long chain 3-amino-1,2-diols". Bioorganic and Medicinal Chemistry Letters 9 6 (1999): 821-826. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033594158&partnerID=MN8TOARS.
    10.1016/S0960-894X(99)00084-0
  256. Padrón, J.M.; Van Moorsel, C.J.A.; Bergman, A.M.; Smitskamp-Wilms, E.; Van Der Wilt, C.L.; Peters, G.J.. "Selective cell kill of the combination of gemcitabine and cisplatin in multilayered postconfluent tumor cell cultures". Anti-Cancer Drugs 10 5 (1999): 445-452. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033437203&partnerID=MN8TOARS.
    10.1097/00001813-199906000-00003
  257. Kokotos, G.; Padron, J. M.; Martin, T.; Gibbons, W. A.; Martin, V. S.. "A general approach to the asymmetric synthesis of unsaturated lipidic alpha-amino acids. The first synthesis of alpha-aminoarachidonic acid". Journal of Organic Chemistry 63 11 (1998): 3741-3744.
    10.1021/jo9715128
  258. Padron, J. M.; Kokotos, G.; Martin, T.; Markidis, T.; Gibbons, W. A.; Martin, V. S.; Padrón, J.M.; et al. "Enantiospecific synthesis of alpha-amino acid semialdehydes: a key step for the synthesis of unnatural unsaturated and saturated alpha-amino acids". Tetrahedron-Asymmetry 9 19 (1998): 3381-3394. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032476172&partnerID=MN8TOARS.
    10.1016/s0957-4166(98)00354-1
  259. Padron, JM; Kokotos, G; Markidis, T; Peters, GJ; Martin, VS. "Unsaturated lipidic a-amino acids derivatives, a novel class of antisignalling agents with cytotoxic activity in vitro". Annals of Oncology (1998): https://publons.com/wos-op/publon/19048560/.
  260. Ramírez, M.A.; Padrón, J.M.; Palazón, J.M.; Martín, V.S.. "Stereocontrolled Synthesis of Cyclic Ethers by Intramolecular Hetero-Michael Addition. 6. A Computational Study of the Annelation to 2,3-Disubstituted Tetrahydropyrans". Journal of Organic Chemistry 62 14 (1997): 4584-4590. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030852861&partnerID=MN8TOARS.
    10.1021/jo961925t
  261. Betancort, J.M.; Martín, V.S.; Padrón, J.M.; Palazón, J.M.; Ramírez, M.A.; Soler, M.A.. "Stereocontrolled Synthesis of Cyclic Ethers by Intramolecular Hetero-Michael Addition. 5. Synthesis of All Diastereoisomers of 2,3,5,6-Tetrasubstituted Tetrahydropyrans". Journal of Organic Chemistry 62 14 (1997): 4570-4583. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030876792&partnerID=MN8TOARS.
    10.1021/jo9619241
  262. Kokotos, G.; Padron, J. M.; Noula, C.; Gibbons, W. A.; Martin, V. S.. "A general approach to the enantiomeric synthesis of lipidic alpha-amino acids, peptides and vicinal amino alcohols". Tetrahedron-Asymmetry 7 3 (1996): 857-866.
    10.1016/0957-4166(96)00084-5
  263. "AN ENANTIOSELECTIVE APPROACH TO THE SYNTHESIS OF POLYCYCLIC ETHERS". Anales de Quimica-international Edition (1993): https://publons.com/wos-op/publon/4260583/.
Capítulo de livro
  1. Padrón, José M.. "Synthesis of Highly Substituted Cyclic Ethers and ¿-Lactones in Their Enantiomeric Forms by Stereoselective Cyclizations". 1997.
    10.1002/chin.199927276
Poster em conferência
  1. Rita Gonçalves-Pereira; Elena M. Sánchez-Fernández; Gabriela B. Plata; José M. Padrón; Terry D. Butters; José M. García Fernández; Carmen Ortiz Mellet. "Antitumor activity of new sp2-iminosugars: Influence of the configurational pattern and the aglycone nature". Trabalho apresentado em 11th International Meeting of the Portuguese Carbohydrate Group – GLUPOR 11 and 6th Iberian Carbohydrate Meeting, 2015.
Pré-impressão
  1. Olszewski M; Maciejewska N; Kallingal A; Chylewska A; Dabrowska AM; Biedulska M; Makowski M; Padrón JM; Baginski M. "Symmetrically substituted carbazole derivatives exert antiproliferative effects through catalytic inhibition of topoisomerase II and apoptosis induction". 2023. http://europepmc.org/abstract/PPR/PPR648902.
    10.21203/rs.3.rs-2807303/v1
  2. Carolina Marques; Aday González-Bakker; José M Padrón. "The Ugi4CR as effective tool to access promising anticancer isatin-based a-acetoamide carboxamide oxindole hybrids". 2023. https://doi.org/10.3762/bxiv.2023.60.v1.
    10.3762/bxiv.2023.60.v1

Propriedade Intelectual

Patente
  1. Padrón, José M.. 2014. "Cyclopentanone compounds, method for obtaining them and their use in the preparation of a drug used for treating inflammatory diseases associated with cellular fibrotic and apoptotic processes".
  2. Padrón, José M.. 2013. "Use of a chemical compound derived from a 1,2,3,5-tetrasubstituted pyrole in the preparation of a drug for use in treating inflammatory diseases involving processes of cellular apoptosis".
  3. Padrón, José M.. 2012. "Pyrimidine urea-derived compound for treating inflammatory diseases".
  4. Padrón, José M.. 2001. "Method for producing carboxylic acids by alcohol oxidation".

Outros

Outra produção
  1. Antiproliferative Activity of Cucurbitaceae Species Extracts from Southeast of Mexico. 2019. Morales-Vela K; Pérez-Sánchez FC; Padron JM; Márquez-Fernández O. http://europepmc.org/abstract/PPR/PPR88761.
    10.20944/preprints201908.0127.v1
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2018/12/01 - 2023/07/27 Catalytic Synthesis of Bioactive Nitrogen Heterocycles
Coorientador
Universidade de Évora, Portugal

Universidad de La Laguna - Campus Anchieta, Espanha

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2011/09 Isolamento e Caracterização de Princípios Activos de Plantas Superiores para o Combate À Tuberculose
Arguente
Sandra Cristina Gonçalves Gouveia (Doutoramento)
Universidade da Madeira, Portugal
Distinções

Prémio

2005 1st Young Cancer Investigators Award
Instituto Canario de Investigación del Cáncer, Espanha
2005 Premio "Ilustre Colegio Oficial de Farmacéuticos de Cádiz"
Academia Iberoamericana de Farmacia, Espanha