Artigo em revista |
- Paloma Begines; Alessandro Bonardi; Simone Giovannuzzi; Alessio Nocentini; Paola Gratteri; Viviana De Luca; Aday González-Bakker;
et al. "Synthesis and investigation of selective human carbonic anhydrase IX, XII inhibitors using coumarins bearing a sulfonamide
or biotin moiety". Chemico-Biological Interactions (2024): https://doi.org/10.1016/j.cbi.2024.111284.
10.1016/j.cbi.2024.111284
- Carolina P. Reyes; Alejandro Ardiles; Laura Anaissi-Afonso; Aday González-Bakker; José M. Padrón; Ignacio A. Jiménez; Félix
Machín; Isabel L. Bazzocchi. "Exploring the Anticancer Potential of Phenolic nor-Triterpenes from Celastraceae Species". International
Journal of Molecular Sciences (2024): https://doi.org/10.3390/ijms25179470.
10.3390/ijms25179470
- Vanesa Quintana; Aday González-Bakker; Adam N. Khan; Juan I. Padrón; Danilo Davyt; José M. Padrón; Guillermo Valdomir. "Novel
tetrahydropyran-triazole hybrids with antiproliferative activity against human tumor cells". Archiv der Pharmazie (2024):
https://doi.org/10.1002/ardp.202400431.
10.1002/ardp.202400431
- Carolina S Marques; Aday González-Bakker; José M Padrón. "The Ugi4CR as effective tool to access promising anticancer isatin-based
a-acetamide carboxamide oxindole hybrids". Beilstein Journal of Organic Chemistry (2024): https://doi.org/10.3762/bjoc.20.104.
10.3762/bjoc.20.104
- Hamdullah Khadim Sheikh; Cindy Juliet Cristancho Ortiz; Tanzila Arshad; José M. Padrón; Prof. Dr. Haroon Khan. "Advancements
in steroidal Pt(II) & Pt(IV) derivatives for targeted chemotherapy (2000–2023)". European Journal of Medicinal Chemistry
(2024): http://dx.doi.org/10.1016/j.ejmech.2024.116438.
10.1016/j.ejmech.2024.116438
- Rosalba González-Solís; Guillermo Mendoza; Antero Ramos; Victor M. Bandala; Leticia Montoya; Aday González-Bakker; José M.
Padrón; Irene Lagunes; Ángel Trigos. "Antiproliferative and Antibacterial Activity of Polyporoid Fungi from Veracruz, Mexico".
International Journal of Medicinal Mushrooms (2024): http://dx.doi.org/10.1615/intjmedmushrooms.2024052840.
10.1615/intjmedmushrooms.2024052840
- Dipakkumar D. Chudasama; Chetan V. Rajput; Manan S. Patel; Jaydeepkumar N. Parekh; Harsh C. Patel; Navin P. Chikhaliya; Adrián
Puerta; José M. Padrón; Kesur R. Ram. "Microwave-induced one-pot synthesis of 3-imidazolyl indole clubbed 1,2,3-triazole hybrids
as antiproliferative agents and density functional theory study". Archiv der Pharmazie (2024): https://doi.org/10.1002/ardp.202300632.
10.1002/ardp.202300632
- Puerta A; González-Bakker A; Pedro Brandão; Pineiro M; Burke AJ; Giovannetti E; Fernandes MX; Padrón JM. "Early pharmacological
profiling of isatin derivatives as potent and selective cytotoxic agents.". Biochemical pharmacology (2024): https://doi.org/10.1016/j.bcp.2024.116059.
10.1016/j.bcp.2024.116059
- Fuentes-Aguilar A; González-Bakker A; Jovanovic M; Stojanov SJ; Puerta A; Gargano A; Jelena Dinic; et al. "Coumarins-lipophilic
cations conjugates: Efficient mitocans targeting carbonic anhydrases.". Bioorganic chemistry (2024): https://doi.org/10.1016/j.bioorg.2024.107168.
10.1016/j.bioorg.2024.107168
- Mateusz Olszewski; Maciejewska N; Kallingal A; Chylewska A; Dabrowska AM; Biedulska M; Mariusz Makowski; Padrón JM; Maciej
Baginski. "Palindromic carbazole derivatives: unveiling their antiproliferative effect via topoisomerase II catalytic inhibition
and apoptosis induction.". Journal of enzyme inhibition and medicinal chemistry (2024): https://europepmc.org/articles/PMC10791108.
10.1080/14756366.2024.2302920
- Vala, Disha P.; Miller, Amy Dunne; Atmasidha, Aditi; Parmar, Mehul P.; Patel, Chirag D.; Upadhyay, Dipti B.; Bhalodiya, Savan
S.; et al. "Click-chemistry mediated synthesis of OTBN-1,2,3-Triazole derivatives exhibiting STK33 inhibition with diverse
anti-cancer activities". Bioorganic Chemistry (2024): https://publons.com/wos-op/publon/68569645/.
10.1016/J.BIOORG.2024.107485
- Mehul P. Parmar; Disha P. Vala; Savan Bhalodiya; Dipti Upadhyay; Chiragkumar Patel; Subham G. Patel; Srinivasa R. Gandholi;
et al. "A green bio-organic catalyst (taurine) promoted one-pot synthesis of (R/S)-2-thioxo-3,4-dihydropyrimidine(TDHPM)-5-carboxanilides:
chiral investigations using circular dichroism and validation by computational approaches". RSC Advances (2024): http://dx.doi.org/10.1039/d4ra01391c.
10.1039/d4ra01391c
- Diaz-Vazquez, Eva D.; Cuellar, Micaela A.; Heredia, Micaela D.; Barolo, Silvia M.; Gonzalez-Bakker, Aday; Padron, Jose M.;
Buden, Maria E.; Martin, Sandra E.; Uberman, Paula M.. "Palladium nanoparticles for the synthesis of phenanthridinones and
benzo[c]chromenes via C-H activation reaction". RSC Advances (2024): https://publons.com/wos-op/publon/68657437/.
10.1039/D4RA02835J
- I. Caroline Vaaland Holmgard; Aday González-Bakker; Eleonora Poeta; Adrián Puerta; Fernandes, M. X.; Barbara Monti; José G.
Fernández-Bolaños; et al. "Coumarin–azasugar–benzyl conjugates as non-neurotoxic dual inhibitors of butyrylcholinesterase
and cancer cell growth". Organic & Biomolecular Chemistry (2024): http://dx.doi.org/10.1039/d4ob00312h.
10.1039/d4ob00312h
- Gonzalez-Solis, Rosalba; Mendoza, Guillermo; Ramos, Antero; Bandala, Victor M.; Montoya, Leticia; Gonzalez-Bakker, Aday; Padron,
Jose M.; Lagunes, Irene; Trigos, Angel. "Antiproliferative and Antibacterial Activity of Polyporoid Fungi from Veracruz, Mexico".
International Journal of Medicinal Mushrooms (2024): https://publons.com/wos-op/publon/68417376/.
- I. Caroline Vaaland; Óscar López; Adrián Puerta; Miguel X. Fernandes; José M. Padrón; José G. Fernández-Bolaños; Magne O.
Sydnes; Emil Lindbäck. "Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition
by tacrine-iminosugar heterodimers". Journal of Enzyme Inhibition and Medicinal Chemistry (2023): https://doi.org/10.1080/14756366.2022.2150762.
10.1080/14756366.2022.2150762
- Tereza Hofmanova; Carolina Marques; Alfonso T. García-Sosa; Óscar López; Luisa Leitzbach; Elisabete P. Carreiro; Aday González-Bakker;
et al. "N-Substituted 3-Aminooxindoles and N-Propargyl Derivatives: Potential Biological Activities against Alzheimer’s Disease".
Results in Chemistry (2023): https://doi.org/10.1016/j.rechem.2023.101032.
10.1016/j.rechem.2023.101032
- Adrián J. Santiago-Benítez; Adrián Puerta; José M. Padrón; Manuel Norte; José J. Fernández; Antonio Hernández Daranas; Francisco
Cen-Pacheco. "Antiproliferative effect of natural and semisynthetic polyethers from Laurencia viridis". Natural Product
Research (2023): https://doi.org/10.1080/14786419.2023.2280176.
10.1080/14786419.2023.2280176
- Sutariya TR; Brahmbhatt GC; Atara HD; Parmar NJ; RajniKant; Gupta VK; Irene Lagunes; et al. "An efficient one-pot synthesis
and docking studies of bioactive new antiproliferative dispiro[oxindole/acenaphthylenone¿benzofuranone] pyrrolidine scaffolds.".
Molecular diversity (2023): https://doi.org/10.1007/s11030-023-10741-4.
10.1007/s11030-023-10741-4
- Subham G. Patel; Paras J. Patel; Dipti B. Upadhyay; Adrián Puerta; Apoorva Malik; Nagesh K. Kandukuri; Rakesh K Sharma; José
M. Padrón; Hitendra M. Patel. "Insights into microwave assisted synthesis of spiro-chromeno[2,3-d]pyrimidines using PEG-OSO3H
catalyst: DFT study and their antiproliferative activity". Journal of Molecular Structure (2023): https://doi.org/10.1016/j.molstruc.2023.136174.
10.1016/j.molstruc.2023.136174
- María Sol Ballari; Exequiel O. J. Porta; Evelyn Arel Zalazar; Carla M. Borini Etichetti; José M. Padrón; Javier E. Girardini;
Guillermo R. Labadie. "Lipophilic modification of salirasib modulates the antiproliferative and antimigratory activity". Bioorganic
& Medicinal Chemistry (2023): https://doi.org/10.1016/j.bmc.2023.117417.
10.1016/j.bmc.2023.117417
- Roshanak Shams; Behmanesh A; Mazhar FN; Vaghari AA; Hossein-Khannazer N; Agarwal T; Massoud Vosough; Padrón JM. "Developed
Bone Biomaterials Incorporated with MicroRNAs to Promote Bone Regeneration: A Systematic Review, Bioinformatics, and Meta-analysis
Study.". ACS biomaterials science & engineering (2023): https://doi.org/10.1021/acsbiomaterials.3c00178.
10.1021/acsbiomaterials.3c00178
- Irene Lagunes; Homero Lumbreras-Martínez; César Espinoza; José M. Padrón; Jorge López-Portillo; Ángel Trigos. "Diversity and
bioactivity of sediment-associated fungi from a mangrove forest in Mexico with different conservation conditions". Latin
American Journal of Aquatic Research (2023): https://doi.org/10.3856/vol51-issue3-fulltext-2971.
10.3856/vol51-issue3-fulltext-2971
- Jovana B. Araškov; Natalia Maciejewska; Mateusz Olszewski; Aleksandar Višnjevac; Vladimir Blagojevic; Henrique S. Fernandes;
Sérgio F. Sousa; et al. "Structural, physicochemical and anticancer study of Zn complexes with pyridyl-based thiazolyl-hydrazones".
Journal of Molecular Structure (2023): https://doi.org/10.1016/j.molstruc.2023.135157.
10.1016/j.molstruc.2023.135157
- Mónica Martínez-Montiel; Laura L. Romero-Hernández; Simone Giovannuzzi; Paloma Begines; Adrián Puerta; Ana I. Ahuja-Casarín;
Miguel X. Fernandes; et al. "Conformationally Restricted Glycoconjugates Derived from Arylsulfonamides and Coumarins: New
Families of Tumour-Associated Carbonic Anhydrase Inhibitors". International Journal of Molecular Sciences (2023): https://www.mdpi.com/1422-0067/24/11/9401.
10.3390/ijms24119401
- Castillo, Q.A.; Padron, J.M.; Keramane, M.; Baez, L.A.; Ovalles, J.N.. "Secondary Metabolites from Chromolaena sinuata var.
viscigerum". Chemistry of Natural Compounds (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85151477424&partnerID=MN8TOARS.
10.1007/s10600-023-03980-2
- Roldan-Pena, Jesus M.; Puerta, Adrian; Dinic, Jelena; Stojanov, Sofija Jovanovic; Gonzalez-Bakker, Aday; Hicke, Francisco
J.; Mishra, Atreyee; et al. "Biotinylated selenocyanates: Potent and selective cytostatic agents". Bioorganic Chemistry
(2023): https://publons.com/wos-op/publon/57032458/.
10.1016/J.BIOORG.2023.106410
- Cobos-Ontiveros, Luis A.; Romero-Hernandez, Laura L.; Mastranzo-Sanchez, Eduardo B.; Colin-Lozano, Blanca; Puerta, Adrian;
Padron, Jose M.; Merino-Montiel, Penelope; Baez, Jose Luis Vega; Montiel-Smith, Sara. "Synthesis, antiproliferative evaluation
and in silico studies of a novel steroidal spiro morpholinone". Steroids (2023): https://publons.com/wos-op/publon/57032457/.
10.1016/J.STEROIDS.2023.109173
- Carolina S. Marques; Aday González-Bakker; José M. Padrón; Anthony J. Burke. "Easy access to Ugi-derived isatin-peptoids and
their potential as small-molecule anticancer agents". New Journal of Chemistry (2023): https://doi.org/10.1039/D2NJ03627D.
10.1039/D2NJ03627D
- Andrés Alguacil; Franco Scalambra; Pablo Lorenzo-Luis; Adrián Puerta; Aday González-Bakker; Zenaida Mendoza; José M. Padrón;
Antonio Romerosa. "Tetranuclear Ru2Cu2 and Ru2Ni2 complexes with nanomolar anticancer activity". Dalton Transactions
(2023): https://doi.org/10.1039/D3DT01284K.
10.1039/D3DT01284K
- Padilla-Pérez, M.C.; Sánchez-Fernández, E.M.; González-Bakker, A.; Puerta, A.; Padrón, J.M.; Martín-Loro, F.; Arroba, A.I.;
García Fernández, J.M.; Mellet, C.O.. "Fluoro-labelled sp2-iminoglycolipids with immunomodulatory properties".
European Journal of Medicinal Chemistry 255 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85153893466&partnerID=MN8TOARS.
10.2139/ssrn.4379429
- Mendez-Delgado, Luis A.; Fuentes-Aguilar, Alma; Meza-Reyes, Socorro; Montiel-Smith, Sara; Vega-Baez, Jose Luis; Padron, Jose
M.; Merino-Montiel, Penelope; Bernes, Sylvain. "Synthesis and antiproliferative activity of new oxazole-steroid glycoconjugates".
Chemistry of Heterocyclic Compounds (2023): https://publons.com/wos-op/publon/66365387/.
10.1007/S10593-024-03277-4
- Merdja, Khedidja; Bendeddouche, Choukry Kamel; Drissi, Mokhtaria; Kaouche, Farah Chafika; Medjahed, Nassima; Padron, Jose
Manuel; Debdab, Mansour; Rahmouni, Mustapha; Belarbi, El Habib. "Synthesis, Thermal, DFT Calculations, HOMO-LUMO, MEP, and
Molecular Docking Analysis of New Derivatives of Imidazolin-4-Ones". Indonesian Journal of Chemistry (2023): https://publons.com/wos-op/publon/66365386/.
10.22146/IJC.87476
- Ballari, Maria Sol; Porta, Exequiel O. J.; Zalazar, Evelyn Arel; Etichetti, Carla M Borini; Padron, Jose M.; Girardini, Javier;
Labadie, Guillermo R. "Lipophilic modification of Salirasib modulate the antiproliferative and antimigratory activity". ChemRxiv
(2023): https://publons.com/wos-op/publon/62963250/.
10.26434/CHEMRXIV-2021-GKFF1-V2
- Suresh Kumar Suthar; Narendra Singh Chundawat; Girdhar Pal Singh; José M. Padrón; Pavan V. Payghan; Yuvraj Kunwar Jhala. "Evaluation
of anti-bacterial activity of novel 2, 3-diaminoquinoxaline derivatives: design, synthesis, biological screening, and molecular
modeling studies". Egyptian Journal of Basic and Applied Sciences 9 1 (2022): 162-179. https://doi.org/10.1080/2314808X.2022.2049085.
10.1080/2314808X.2022.2049085
- Tereza Cristina Santos Evangelista; Óscar López; Adrián Puerta; Miguel X. Fernandes; Sabrina Baptista Ferreira; José M. Padrón;
José G. Fernández-Bolaños; Magne O. Sydnes; Emil Lindbäck. "A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential
inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE)". Journal of Enzyme Inhibition and Medicinal
Chemistry (2022): https://doi.org/10.1080/14756366.2022.2117912.
10.1080/14756366.2022.2117912
- Ruth E. Barrientos; Elena Ibáñez; Adrián Puerta; José M. Padrón; Adrián Paredes; Fredi Cifuentes; Javier Romero-Parra; et
al. "Phenolic Fingerprinting and Bioactivity Profiling of Extracts and Isolated Compounds from Gypothamnium pinifolium Phil.".
Antioxidants (2022): https://doi.org/10.3390/antiox11122313.
10.3390/antiox11122313
- Vanesa Quintana; Aday González-Bakker; Juan I. Padrón; Víctor S. Martín; José M. Padrón; Danilo Davyt; Guillermo Valdomir.
"Synthesis of Oxazole–Tetrahydropyran Hybrids and Study on Their Antiproliferative Activity Against Human Tumour Cells". European
Journal of Organic Chemistry (2022): https://doi.org/10.1002/ejoc.202200528.
10.1002/ejoc.202200528
- Martha Velueta-Viveros; Macarena Martínez-Bailén; Adrián Puerta; Laura L. Romero-Hernández; Vladimír Kren; Penélope Merino-Montiel;
Sara Montiel-Smith; et al. "Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against
Alzheimer’s disease". Bioorganic Chemistry 127 (2022): 105983-105983. https://doi.org/10.1016/j.bioorg.2022.105983.
10.1016/j.bioorg.2022.105983
- Adrián Puerta; Aday González-Bakker; Guido Santos; José M. Padrón. "Early Pharmacological Profiling of Antiproliferative Compounds
by Live Cell Imaging". Molecules (2022): https://doi.org/10.3390/molecules27165261.
10.3390/molecules27165261
- Suresh Kumar Suthar; Narendra Singh Chundawat; Girdhar Pal Singh; José M. Padrón; Yuvraj Kunwar Jhala. "Quinoxaline: A comprehension
of current pharmacological advancement in medicinal chemistry". European Journal of Medicinal Chemistry Reports (2022):
https://doi.org/10.1016/j.ejmcr.2022.100040.
10.1016/j.ejmcr.2022.100040
- Sanja B. Markovic; Natalia Maciejewska; Mateusz Olszewski; Aleksandar Višnjevac; Adrián Puerta; José M. Padrón; Irena Novakovic;
et al. "Study of the anticancer potential of Cd complexes of selenazoyl-hydrazones and their sulfur isosters". European
Journal of Medicinal Chemistry (2022): https://doi.org/10.1016/j.ejmech.2022.114449.
10.1016/j.ejmech.2022.114449
- Giulia Arrighi; Adrián Puerta; Andrea Petrini; Francisco J. Hicke; Alessio Nocentini; Miguel X. Fernandes; José M. Padrón;
et al. "Squaramide-Tethered Sulfonamides and Coumarins: Synthesis, Inhibition of Tumor-Associated CAs IX and XII and Docking
Simulations". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms23147685.
10.3390/ijms23147685
- María F. Beer; Guillermo F. Reta; Adrián Puerta; Augusto E. Bivona; Andrés Sánchez Alberti; Natacha Cerny; Emilio L. Malchiodi;
et al. "Oxonitrogenated Derivatives of Eremophilans and Eudesmans: Antiproliferative and Anti-Trypanosoma cruzi Activity".
Molecules 27 10 (2022): 3067-3067. https://doi.org/10.3390/molecules27103067.
10.3390/molecules27103067
- Carlos Fernández-Galleguillos; Javier Romero-Parra; Adrián Puerta; José M. Padrón; Mario J. Simirgiotis. "Alkaloid Profiling,
Anti-Enzymatic and Antiproliferative Activity of the Endemic Chilean Amaryllidaceae Phycella cyrtanthoides". Metabolites
12 2 (2022): 188-188. https://doi.org/10.3390/metabo12020188.
10.3390/metabo12020188
- Paloma Begines; Sergio Martos; Irene Lagunes; Inés Maya; José M. Padrón; Óscar López; José G. Fernández-Bolaños. "Chemoselective
Preparation of New Families of Phenolic-Organoselenium Hybrids—A Biological Assessment". Molecules 27 4 (2022): 1315-1315.
https://doi.org/10.3390/molecules27041315.
10.3390/molecules27041315
- "Koanolides B-D, new sesquiterpene lactones from Koanophyllon gibbosum". Phytochemistry Letters 47 (2022): 63-66. http://dx.doi.org/10.1016/j.phytol.2021.11.009.
10.1016/j.phytol.2021.11.009
- Óscar López; José M. Padrón. "Iridium- and Palladium-Based Catalysts in the Pharmaceutical Industry". Catalysts 12
2 (2022): 164-164. https://doi.org/10.3390/catal12020164.
10.3390/catal12020164
- "2-Aminobenzoxazole-appended coumarins as potent and selective inhibitors of tumour-associated carbonic anhydrases". Journal
of Enzyme Inhibition and Medicinal Chemistry 37 1 (2022): 168-177. http://dx.doi.org/10.1080/14756366.2021.1998026.
10.1080/14756366.2021.1998026
- "Straightforward access to novel mitochondriotropics derived from 2-arylethanol as potent and selective antiproliferative
agents". European Journal of Medicinal Chemistry 228 (2022): 113980-113980. http://dx.doi.org/10.1016/j.ejmech.2021.113980.
10.1016/j.ejmech.2021.113980
- Jovana B. Araškov; Aleksandar Višnjevac; Jasminka Popovic; Vladimir Blagojevic; Henrique S. Fernandes; Sérgio F. Sousa; Irena
Novakovic; et al. "Zn(ii) complexes with thiazolyl–hydrazones: structure, intermolecular interactions, photophysical properties,
computational study and anticancer activity". CrystEngComm (2022): https://doi.org/10.1039/D2CE00443G.
10.1039/D2CE00443G
- Carballo, Ruben M.; Padron, Jose M.; Fernandez, Israel; Cruz, Daniel A.; Grmus, Luana; Martin, Victor S.; Padron, Juan I..
"Iron(III)-Catalyzed Synthesis of 2-Alkyl Homoallyl Sulfonyl Amides: Antiproliferative Study and Reactivity Scope of Aza-Prins
Cyclization". The Journal of Organic Chemistry (2022): https://publons.com/wos-op/publon/53479991/.
10.1021/ACS.JOC.2C01267
- Subham G. Patel; Aday González-Bakker; Ruturajsinh M. Vala; Paras J. Patel; Adrián Puerta; Apoorva Malik; Rakesh K. Sharma;
José M. Padrón; Hitendra M. Patel. "Microwave-assisted multicomponent synthesis of antiproliferative 2,4-dimethoxy-tetrahydropyrimido[4,5-b]quinolin-6(7H)-ones".
RSC Advances (2022): https://doi.org/10.1039/D2RA04669E.
10.1039/D2RA04669E
- Suelsen, Valeria P.; Athanassopoulos, Constantinos M.; Padron, Jose M.; Tamura, Rodrigo E.. "Editorial: Natural compounds
as scaffolds for the discovery of new anti-cancer drugs: Focus on terpenoids and flavonoids". Frontiers in Pharmacology
(2022): https://publons.com/wos-op/publon/56024718/.
10.3389/FPHAR.2022.984849
- Ortiz, Federico; Tassano, Tiago; Ingold, Mariana; de la Sovera, Victoria; Puerta, Adrian; Padron, Jose M.; Lopez, Gloria,
V; Porcal, Williams. "Greener approach for the synthesis of nitrovinylfurans from biomass-derived 5-hydroxymethyfurfural as
selective antiproliferative agents". Sustainable Chemistry and Pharmacy (2022): https://publons.com/wos-op/publon/56024717/.
10.1016/J.SCP.2022.100828
- Alov, Petko; Al Sharif, Merilin; Aluani, Denitsa; Chegaev, Konstantin; Dinic, Jelena; Rankov, Aleksandra Divac; Fernandes,
Miguel X.; et al. "A Comprehensive Evaluation of Sdox, a Promising H2S-Releasing Doxorubicin for the Treatment
of Chemoresistant Tumors". Frontiers in Pharmacology (2022): https://publons.com/wos-op/publon/51674836/.
10.3389/FPHAR.2022.831791
- Lacret, R.; Puerta, A.; Granica, S.; González-Bakker, A.; Hevia, D.; Teng, Y.; Sánchez-Mateo, C.C.; Pérez de Paz, P.L.; Padrón,
J.M.. "Bioactive Potential: A Pharmacognostic Definition through the Screening of Four Hypericum Species from the Canary Islands".
Molecules 27 18 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85138405490&partnerID=MN8TOARS.
10.3390/molecules27186101
- Elena M. Sánchez-Fernández; Raquel García-Hernández; Francisco Gamarro; Ana I. Arroba; Manuel Aguilar-Diosdado; José M. Padrón;
José M. García Fernández; Carmen Ortiz Mellet. "Synthesis of sp2-Iminosugar Selenoglycolipids as Multitarget Drug Candidates
with Antiproliferative, Leishmanicidal and Anti-Inflammatory Properties". Molecules (2021): https://doi.org/10.3390/molecules26247501.
10.3390/molecules26247501
- "Ugi adducts of isatin as promising antiproliferative agents with druglike properties". Asian Journal of Organic Chemistry
(2021): http://dx.doi.org/10.1002/ajoc.202100684.
10.1002/ajoc.202100684
- Jovana B. Araškov; Milan Nikolic; Stevan Armakovic; Sanja Armakovic; Marko Rodic; Aleksandar Višnjevac; José M. Padrón; Tamara
R. Todorovic; Nenad R. Filipovic. "Structural, antioxidant, antiproliferative and in¿silico study of pyridine-based hydrazonyl¿selenazoles
and their sulphur isosteres". Journal of Molecular Structure 1240 (2021): 130512-130512. https://doi.org/10.1016/j.molstruc.2021.130512.
10.1016/j.molstruc.2021.130512
- "Novel 1,2,3-triazole epicinchonas: Transitioning from organocatalysis to biological activities". Synthetic Communications
(2021): 1-21. http://dx.doi.org/10.1080/00397911.2021.1948575.
10.1080/00397911.2021.1948575
- Giovanna Bosica; Kaylie Demanuele; José Manuel Padrón; Adrián Puerta. "Correction: One-pot multicomponent green Hantzsch synthesis
of 1,2-dihydropyridine derivatives with antiproliferative activity". Beilstein Journal of Organic Chemistry (2021):
https://doi.org/10.3762/bjoc.17.130.
10.3762/bjoc.17.130
- Carlos Fernández-Galleguillos; Luisa Quesada-Romero; Adrián Puerta; José M. Padrón; Ernane Souza; Javier Romero-Parra; Mario
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of Tubulin-targeting Dibenzothiazines with Antiproliferative Activity as Novel Heterocycle Building Block.". ChemMedChem
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of extracts of Ganoderma strains grown in vitro.". Food science and biotechnology (2021): http://europepmc.org/abstract/med/34123467.
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Transfer for the Synthesis of Guaianolide Analogs with Enhanced Antiproliferative Activity". European Journal of Organic
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Gardas; Hitendra M. Patel. "Synthesis and in vitro study of antiproliferative benzyloxy dihydropyrimidinones". Archiv der
Pharmazie (2021): https://doi.org/10.1002/ardp.202000466.
10.1002/ardp.202000466
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María Auxiliadora Dea-Ayuela. "Biological Profiling of Semisynthetic C19-Functionalized Ferruginol and Sugiol Analogues".
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antiproliferative potential of fungi associated with coral and algae collected from a Veracruz Reef System, Gulf of Mexico".
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antiproliferative activity against human solid tumor cell lines". ChemRxiv (2021): https://publons.com/wos-op/publon/56024779/.
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derivatives with antiproliferative activity". Beilstein Journal of Organic Chemistry (2020): https://doi.org/10.3762/bjoc.16.235.
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Phenolic-Selenium Conjugates: Potent and Selective Antiproliferative Agents Overcoming P-gp Resistance". Pharmaceuticals
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from 1,4-naphthoquinone". Medicinal Chemistry Research (2020): http://dx.doi.org/10.1007/s00044-020-02617-1.
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10.1016/j.drup.2020.100713
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and Acetylcholinesterase Inhibitors, Antioxidant, and Antiproliferative Agents". Applied Sciences (2020): http://dx.doi.org/10.3390/app10082889.
10.3390/app10082889
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Hybrids Using Multicomponent 1,3-Dipolar Cycloaddition (Click)-Biginelli Reactions: Anticancer Activity". Synlett 31
6 (2020): 615-621. http://www.scopus.com/inward/record.url?eid=2-s2.0-85082107784&partnerID=MN8TOARS.
10.1055/s-0039-1690781
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Trace of hope for pancreatic cancer therapy. a systematic review". Cancer Management and Research 12 (2020): 2393-2404.
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10.2147/CMAR.S245872
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R.; et al. "In vitro and in silico screening of 2,4,5-Trisubstituted imidazole derivatives as potential xanthine oxidase and
acetylcholinesterase inhibitors, antioxidant, and antiproliferative agents". Applied Sciences (Switzerland) 10 8 (2020):
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of tetrahydro-spiro[pyrazolo[4,3-f]quinoline]-8,5'-pyrimidines and tetrahydro-pyrazolo[4,3-f]pyrimido[4,5-b]quinolinesviaselective
multiple C-C bond formation under metal-free conditions". RSC Advances 10 33 (2020): 19600-19609. http://www.scopus.com/inward/record.url?eid=2-s2.0-85085640120&partnerID=MN8TOARS.
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the syntheses of tetrahydro-spiro[pyrazolo[4,3-f]quinoline]-8,5'-pyrimidines and tetrahydro-pyrazolo[4,3-f]pyrimido[4,5-b]quinolines
via selective multiple C–C bond formation under metal-free conditions". RSC Advances (2020): https://doi.org/10.1039/D0RA02990D.
10.1039/D0RA02990D
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"Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar
BuChE inhibitors". European Journal of Medicinal Chemistry 181 (2019): 111550-111550. https://doi.org/10.1016/j.ejmech.2019.07.053.
10.1016/j.ejmech.2019.07.053
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Francisco Gamarro; et al. "Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory
properties towards anti-tumor, anti-leishmanial and anti-inflammatory therapies". European Journal of Medicinal Chemistry
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10.1016/j.ejmech.2019.111604
- Alejandra Cortés-Percino; José Luis Vega-Báez; Anabel Romero-López; Adrián Puerta; Penélope Merino-Montiel; Socorro Meza-Reyes;
José M. Padrón; Sara Montiel-Smith. "Synthesis and Evaluation of Pyrimidine Steroids as Antiproliferative Agents". Molecules
(2019): https://doi.org/10.3390/molecules24203676.
10.3390/molecules24203676
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as new multitarget antiproliferative agents: Synthesis, biological evaluation and in silico calculations". European Journal
of Medicinal Chemistry 179 (2019): 493-501. https://doi.org/10.1016/j.ejmech.2019.06.073.
10.1016/j.ejmech.2019.06.073
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isolated from an alkaline crater lake in Puebla, Mexico". Natural Product Research (2019): http://dx.doi.org/10.1080/14786419.2019.1669032.
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Gamarro; Carmen Ortiz Mellet. "Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp2-Iminosugar Glycolipids".
Molecules 24 16 (2019): 2882-2882. https://doi.org/10.3390/molecules24162882.
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Species in the Genera Eriolarynx and Deprea". Journal of Natural Products (2019): https://doi.org/10.1021/acs.jnatprod.9b00117.
10.1021/acs.jnatprod.9b00117
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Dea-Ayuela; Miguel A. González-Cardenete. "Synthesis and Biological Studies of (+)-Liquiditerpenoic Acid A (Abietopinoic Acid)
and Representative Analogues: SAR Studies". Journal of Natural Products (2019): https://doi.org/10.1021/acs.jnatprod.8b00884.
10.1021/acs.jnatprod.8b00884
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targeting agent, overcomes paclitaxel induced resistance in cancer cells". Investigational New Drugs (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85067282745&partnerID=MN8TOARS.
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of NO-Donor Compounds with Potent Antiproliferative Activity Based on Green Multicomponent Reactions". ChemMedChem
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Activities". Pharmacognosy Journal 11 3 (2019): 493-495. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068703450&partnerID=MN8TOARS.
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activity of new 2-glyco-3-nitro-2H-chromenes". Bioorganic Chemistry 87 (2019): 112-116. http://www.scopus.com/inward/record.url?eid=2-s2.0-85062841003&partnerID=MN8TOARS.
10.1016/j.bioorg.2019.03.016
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lactone from Koanophyllon gibbosum". Tetrahedron Letters 60 25 (2019): 1640-1642. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065926503&partnerID=MN8TOARS.
10.1016/j.tetlet.2019.05.036
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lactone derivatives: Cytotoxic activity and selectivity of action". Molecules 24 6 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85063585006&partnerID=MN8TOARS.
10.3390/molecules24061113
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activity of biomass extract from Pseudomonas cedrina". Electronic Journal of Biotechnology 40 (2019): 40-44. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065042942&partnerID=MN8TOARS.
10.1016/j.ejbt.2019.03.010
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M.R.. "New pyrazolyl-dibenzo[b,e][1,4]diazepinones: room temperature one-pot synthesis and biological evaluation". Molecular
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evaluation". Bioorganic Chemistry 86 (2019): 137-150. http://www.scopus.com/inward/record.url?eid=2-s2.0-85060495712&partnerID=MN8TOARS.
10.1016/j.bioorg.2019.01.029
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"Silver-based monomer and coordination polymer with organic thiocyanate ligand: Structural, computational and antiproliferative
activity study". Polyhedron 173 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85072584514&partnerID=MN8TOARS.
10.1016/j.poly.2019.114132
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(2019): http://dx.doi.org/10.31083/j.jmcm.2019.02.7181.
10.31083/j.jmcm.2019.02.7181
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10.31083/j.jmcm.2019.04.5121
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(2018): http://dx.doi.org/10.31083/j.jmcm.2018.04.401.
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lagoon, Veracruz, Mexico". Scientia Fungorum (2018): http://dx.doi.org/10.33885/sf.2018.48.1234.
10.33885/sf.2018.48.1234
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of Molecular and Clinical Medicine (2018): http://dx.doi.org/10.31083/j.jmcm.2018.02.003.
10.31083/j.jmcm.2018.02.003
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(2018): http://dx.doi.org/10.31083/j.jmcm.2018.02.004.
10.31083/j.jmcm.2018.02.004
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Sara Montiel-Smith. "Synthesis of unprecedented steroidal spiro heterocycles as potential antiproliferative drugs". European
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10.1016/j.ejmech.2017.10.063
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as antiproliferative agents". Future Medicinal Chemistry 10 3 (2018): 319-334. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041956361&partnerID=MN8TOARS.
10.4155/fmc-2017-0053
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medicinal wood-destroying mushrooms from Russia". International Journal of Medicinal Mushrooms 20 1 (2018): 1-11. http://www.scopus.com/inward/record.url?eid=2-s2.0-85044057437&partnerID=MN8TOARS.
10.1615/IntJMedMushrooms.2018025250
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as novel selective MAO inhibitors with antiproliferative and antioxidant activities: Experimental and In-silico studies".
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10.3389/fchem.2018.00247
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activity of new 2-glyco-3-nitro-1,2-dihydroquinolines and quinolines synthesized under solventless conditions promoted by
neutral alumina". New Journal of Chemistry 42 22 (2018): 18342-18347. http://www.scopus.com/inward/record.url?eid=2-s2.0-85056143649&partnerID=MN8TOARS.
10.1039/c8nj03372b
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"Anti-Proliferative 1,4-Dihydropyridine and Pyridine Derivatives Synthesized through a Catalyst-Free, One-Pot Multi-Component
Reaction". ChemistrySelect 3 43 (2018): 12163-12168. http://www.scopus.com/inward/record.url?eid=2-s2.0-85057018343&partnerID=MN8TOARS.
10.1002/slct.201802537
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Assisted by CASE-3D with Residual Dipolar Couplings and Isotropic 1H/13C NMR Chemical Shifts". Journal
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10.1021/acs.jnatprod.8b00162
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triazole-linked hybrids with selective antiproliferative activity against human tumour cells". New Journal of Chemistry
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10.1039/c8nj02388c
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M.. "Pinnatifidenyne-derived ethynyl oxirane acetogenins from laurencia viridis". Marine Drugs 16 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85040325981&partnerID=MN8TOARS.
10.3390/md16010005
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synthesis of tocopherol analogues with antiproliferative activities". European Journal of Medicinal Chemistry 143 (2018):
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Ru-Zn Complex [RuCp(PPh3)2-µ-dmoPTA-1¿P:2¿2N,N'-ZnCl2](CF3SO3)".
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10.1016/j.steroids.2017.03.008
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10.1016/j.ejps.2017.05.011
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methyl D-ribofuranosides". Bioorganic and Medicinal Chemistry Letters 27 16 (2017): 3674-3677. http://www.scopus.com/inward/record.url?eid=2-s2.0-85024120200&partnerID=MN8TOARS.
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- "Abietane diterpenoids from some salvia species: Chemical transformations and antiproliferative activity". Planta Medica
(2012): https://publons.com/wos-op/publon/19048554/.
10.1055/S-0032-1321023
- León LG; Giovannetti E; Alecci C; Giancola F; Funel N; Zucali P; Peters GJ; et al. "Antiproliferative effects of novel aliphatic
acetogenin analogs against aggressive solid tumor cell lines.". In Vivo 25 2 (2011): 203-207. http://europepmc.org/abstract/med/21471536.
- Aleman, Jose; del Solar, Virginia; Alvarez-Valdes, Amparo; Rios-Luci, Carla; Padron, Jose M.; Navarro-Ranninger, Carmen. "Novel
N-sulfonamide trans-platinum complexes: synthesis, reactivity and in vitro evaluation". Medchemcomm 2 8 (2011): 789-793.
10.1039/c1md00070e
- Esteve, Judit; Lorente, Adriana; Romea, Pedro; Urpi, Felix; Rios-Luci, Carla; Padron, Jose M.. "Synthesis and Biological Evaluation
of 1-Deoxy-5-hydroxysphingosine Derivatives". European Journal of Organic Chemistry 5 (2011): 960-967.
10.1002/ejoc.201001268
- Rios-Luci, Carla; Leon, Leticia G.; Mena-Cruz, Adrian; Perez-Roth, Eduardo; Lorenzo-Luis, Pablo; Romerosa, Antonio; Padron,
Jose M.. "Antiproliferative activity of dmoPTA-Ru(II) complexes against human solid tumor cells". Bioorganic & Medicinal
Chemistry Letters 21 15 (2011): 4568-4571.
10.1016/j.bmcl.2011.05.116
- Rios-Luci, Carla; Dominguez-Kelly, Raquel; Leon, Leticia G.; Diaz-Rodriguez, Elena; Freire, Raimundo; Pandiella, Atanasio;
Cikotiene, Inga; Padron, Jose M.. "A modular approach to trim cellular targets in anticancer drug discovery". Bioorganic
& Medicinal Chemistry Letters 21 22 (2011): 6641-6645.
10.1016/j.bmcl.2011.09.069
- Leon, Leticia G.; Giovannetti, Elisa; Alecci, Claudia; Giancola, Fiorella; Funel, Niccola; Zucali, Paolo; Peters, Godefridus
J.; Manuel Padron, Jose. "Cytotoxicity of Aliphatic Acetogenin Analogs against two of the most Aggressive Solid Tumors". The
FASEB Journal (2011): https://publons.com/wos-op/publon/11842720/.
- Rios-Luci, Carla P.; Leon, Leticia G.; Perez-Roth, Eduardo; Padron, Jose M.. "Endoreduplication induced by a novel family
of DNA Topoisomerase II inhibitors". The FASEB Journal (2011): https://publons.com/wos-op/publon/28244206/.
- José M. Padrón. "Antimicrobial Drug Resistance (2 volumes). Edited by Douglas L. Mayers.". ChemMedChem 5 6 (2010):
960-961. http://dx.doi.org/10.1002/cmdc.201000025.
10.1002/cmdc.201000025
- Rudys, Simonas; Rios-Luci, Carla; Perez-Roth, Eduardo; Cikotiene, Inga; Padron, Jose M.. "Antiproliferative activity of novel
benzo b 1,6 naphthyridines in human solid tumor cell lines". Bioorganic & Medicinal Chemistry Letters 20 5 (2010):
1504-1506.
10.1016/j.bmcl.2010.01.112
- Bonifazi, Evelyn L.; Rios-Luci, Carla; Leon, Leticia G.; Burton, Gerardo; Padron, Jose M.; Misico, Rosana I.. "Antiproliferative
activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol". Bioorganic & Medicinal
Chemistry 18 7 (2010): 2621-2630.
10.1016/j.bmc.2010.02.032
- Messori, Luigi; Casini, Angela; Gabbiani, Chiara; Michelucci, Elena; Cubo, Leticia; Rios-Luci, Carla; Padron, Jose M.; Navarro-Ranninger,
Carmen; Quiroga, Adoracion G.. "Cytotoxic Profile and Peculiar Reactivity with Biomolecules of a Novel "Rule-Breaker" Iodidoplatinum(II)
Complex". Acs Medicinal Chemistry Letters 1 8 (2010): 381-385.
10.1021/ml100081e
- Machin, Ruben P.; Veleiro, Adriana S.; Nicotra, Viviana E.; Oberti, Juan C.; Padron, Jose M.. "Antiproliferative Activity
of Withanolides against Human Breast Cancer Cell Lines". Journal of Natural Products 73 5 (2010): 966-968.
10.1021/np9006734
- Tereza Rojo de Almeida, Maria; Rios-Luci, Carla; Padron, Jose M.; Palermo, Jorge A.. "Antiproliferative terpenoids and alkaloids
from the roots of Maytenus vitis-idaea and Maytenus spinosa". Phytochemistry 71 14-15 (2010): 1741-1748.
10.1016/j.phytochem.2010.06.023
- Garcia, Celina; Leon, Leticia G.; Pungitore, Carlos R.; Rios-Luci, Carla; Daranas, Antonio H.; Montero, Juan C.; Pandiella,
Atanasio; et al. "Enhancement of antiproliferative activity by molecular simplification of catalpol". Bioorganic & Medicinal
Chemistry 18 7 (2010): 2515-2523.
10.1016/j.bmc.2010.02.044
- Leon, Leticia G.; Rios-Luci, Carla; Tejedor, David; Perez-Roth, Eduardo; Montero, Juan C.; Pandiella, Atanasio; Garcia-Tellado,
Fernando; Padron, Jose M.. "Mitotic Arrest Induced by a Novel Family of DNA Topoisomerase II Inhibitors". Journal of Medicinal
Chemistry 53 9 (2010): 3835-3839.
10.1021/jm100155y
- Rios Luci, Carla Patricia; Leon, Leticia G.; Montero, Juan C.; Tejedor, David; Pandiella, Atanasio; Garcia-Tellado, Fernando;
Padron, Jose M.. "Mitotic arrest induced by propargylic enol ethers derivatives". The FASEB Journal (2010): https://publons.com/wos-op/publon/28244207/.
- José G. Napolitano; Manuel Norte; José M. Padrón; José J. Fernández; Antonio Hernández Daranas; Napolitano, J.G.; Norte, M.;
et al. "Belizeanolide, a Cytotoxic Macrolide from the Dinoflagellate Prorocentrum belizeanum". Angew. Chem. 121 4 (2009):
810-813. http://dx.doi.org/10.1002/ange.200804023.
10.1002/ange.200804023
- Pudziuvelyte, Erika; Rios-Luci, Carla; Leon, Leticia G.; Cikotiene, Inga; Padron, Jose M.. "Synthesis and antiproliferative
activity of 2,4-disubstituted 6-aryl-7H-pyrrolo 3,2-d pyrimidin-7-one 5-oxides". Bioorganic & Medicinal Chemistry 17
14 (2009): 4955-4960.
10.1016/j.bmc.2009.05.078
- Leon, Leticia G.; Donadel, Osvaldo J.; Tonn, Carlos E.; Padron, Jose M.. "Tessaric acid derivatives induce G(2)/M cell cycle
arrest in human solid tumor cell lines". Bioorganic & Medicinal Chemistry 17 17 (2009): 6251-6256.
10.1016/j.bmc.2009.07.053
- Hubeek, I.; Comijn, E.M.; Van der Wilt, C.L.; Merriman, R.L.; Padron, J.M.; Kaspers, G.J.L.; Peters, G.J.. "CI-994 (N-acetyl-dinaline)
in combination with conventional anti-cancer agents is effective against acute myeloid leukemia in vitro and in vivo". Oncology
Reports 19 6 (2008): 1517-1523. http://www.scopus.com/inward/record.url?eid=2-s2.0-48849094081&partnerID=MN8TOARS.
10.3892/or.19.6.1517
- Leon, Leticia G.; Machin, Ruben P.; Rodriguez, Carmen M.; Ravelo, Jose L.; Martin, Victor S.; Padron, Jose M.. "gamma-lactones
alpha,beta- and beta,gamma-fused to carbocycles as novel antiproliferative drugs". Bioorganic & Medicinal Chemistry Letters
18 19 (2008): 5171-5173.
10.1016/j.bmcl.2008.08.098
- Leon, Leticia G.; Carballo, Ruben M.; Vega-Hernandez, Maria C.; Miranda, Pedro O.; Martin, Victor S.; Padron, Juan I.; Padron,
Jose M.. "ß'-Hydroxy-a,ß-Unsaturated Ketones: A new pharmacophore for the design of anticancer drugs. Part 2". Chemmedchem
3 11 (2008): 1740-1747.
10.1002/cmdc.200800212
- "In vitro antiproliferative activity of Xanthones and Guttiferones from Securidaca spp". Planta Medica (2008): https://publons.com/wos-op/publon/11927107/.
10.1055/S-0028-1084149
- Sousa, I; Kairys, V; Padron, J. M.; Fernandes, M. X.. "Identification of molecular targets in anti-cancer therapy using protein-ligand
docking". Planta Medica (2008): https://publons.com/wos-op/publon/19048555/.
10.1055/S-0028-1084827
- Bijnsdorp IV; Comijn EM; Padron JM; Gmeiner WH; Peters GJ. "Mechanisms of action of FdUMP[10]: metabolite activation and thymidylate
synthase inhibition.". Oncology reports (2007): http://europepmc.org/abstract/med/17549381.
10.3892/or.18.1.287
- I. Cordova; L. G. Leon; F. Leon; L. San Andres; J. G. Luis; J. M. Padron. "Synthesis and Antiproliferative Activity of Novel
Sugiol ß-Amino Alcohol Analogues.". ChemInform 38 12 (2007): http://dx.doi.org/10.1002/chin.200712191.
10.1002/chin.200712191
- Bijnsdorp, I.V.; Comijn, E.M.; Padron, J.M.; Gmeiner, W.H.; Peters, G.J.; Bijnsdorp, I. V.; Comijn, E. M.; et al. "Mechanisms
of action of FdUMP[10]: Metabolite activation and thymidylate synthase inhibition". Oncology Reports 18 1 (2007): 287-291.
http://www.scopus.com/inward/record.url?eid=2-s2.0-34548017882&partnerID=MN8TOARS.
10.3892/or.18.1.287
- Pungitore, C.R.; Padrón, J.M.; Leon, L.G.; García, C.; Ciuffo, G.M.; Martin, V.S.; Tonn, C.E.; et al. "Inhibition of DNA topoisomerase
I and growth inhibition of human cancer cell lines by an oleanane from Junellia aspera (Verbenaceae)". Cellular and Molecular
Biology 53 3 (2007): 13-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-84965098356&partnerID=MN8TOARS.
10.1170/T791
- Leon, Leticia G.; Carballo, Ruben M.; Vega-Hernandez, Maria C.; Martin, Victor S.; Padron, Juan I.; Padron, Jose M.. "Antiproliferative
activity of 2-alkyl-4-halopiperidines and 2-alkyl-4-halo-1,2,5,6-tetrahydropyridines in solid tumor cell lines". Bioorganic
& Medicinal Chemistry Letters 17 10 (2007): 2681-2684.
10.1016/j.bmcl.2007.03.010
- Leon, Leticia G.; Miranda, Pedro O.; Martin, Victor S.; Padron, Juan I.; Padron, Jose M.. "Antiproliferative activity of 4-chloro-5,6-dihydro-2H-pyrans.
Part 2: Enhancement of drug cytotoxicity". Bioorganic & Medicinal Chemistry Letters 17 11 (2007): 3087-3090.
10.1016/j.bmcl.2007.03.045
- Sanhueza, Carlos A.; Mayato, Carlos; Machin, Ruben P.; Padron, Jose M.; Dorta, Rosa L.; Vazquez, Jesus T.. "Cytotoxic effects
of C-glycosides in HOS and HeLa cell lines". Bioorganic & Medicinal Chemistry Letters 17 13 (2007): 3676-3681.
10.1016/j.bmcl.2007.04.060
- Pungitore, Carlos R.; Leon, Leticia G.; Garcia, Celina; Martin, Victor S.; Tonn, Carlos E.; Padron, Jose M.. "Novel antiproliferative
analogs of the Taq DNA polymerase inhibitor catalpol". Bioorganic & Medicinal Chemistry Letters 17 5 (2007): 1332-1335.
10.1016/j.bmcl.2006.11.086
- Donadel, Osvaldo J.; Martin, Tomas; Martin, Victor S.; Padron, Jose M.. "Samarium(II) promoted stereoselective synthesis of
antiproliferative cis-beta-alkoxy-gamma-alkyl-gamma-lactones". Bioorganic & Medicinal Chemistry Letters 17 1 (2007):
18-21.
10.1016/j.bmcl.2006.10.005
- Carrillo, R.; León, L.G.; Martín, T.; Martín, V.S.; Padrón, J.M.. "Synthesis and antiproliferative activity of (2R,3R)-disubstituted
tetrahydropyrans. Part 2: Effect of side chain homologation". Bioorganic and Medicinal Chemistry Letters 17 3 (2007):
780-783. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846214455&partnerID=MN8TOARS.
10.1016/j.bmcl.2006.10.066
- "Isolation, chemical transformations, and antiproliferative activity against human cancer cell lines of abietane cliterpenes
from two Mexican Salvia species". Planta Medica (2007): https://publons.com/wos-op/publon/19048556/.
- Jose M. Padron; Pedro O. Miranda; Juan I. Padron; Victor S. Martin. "ß'-Hydroxy-a,ß-Unsaturated Ketones: A New Pharmacophore
for the Design of Anticancer Drugs.". ChemInform 37 28 (2006): http://dx.doi.org/10.1002/chin.200628059.
10.1002/chin.200628059
- Miranda, Pedro O.; Padron, Jose M.; Padron, Juan I.; Villar, Jesus; Martin, Victor S.. "Prins-type synthesis and SAR study
of cytotoxic alkyl chloro dihydropyrans". Chemmedchem 1 3 (2006): 323-329.
10.1002/cmdc.200500057
- Padron, J. M.. "Sphingolipids in anticancer therapy". Current Medicinal Chemistry 13 7 (2006): 755-770.
10.2174/092986706776055553
- Crisostomo, F. R. P.; Carrillo, R.; Leon, L. G.; Martin, T.; Padron, J. M.; Martin, V. S.. "Molecular simplification in bioactive
molecules: Formal synthesis of (+)-muconin". Journal of Organic Chemistry 71 6 (2006): 2339-2345.
10.1021/jo0524674
- Miranda, P. O.; Leon, L. G.; Martin, V. S.; Padron, J. I.; Padron, J. M.; Pedro O. Miranda; Leticia G. Leon; et al. "One-pot
synthesis and SAR study of cis-2,6-dialkyl-4-chloro-tetrahydropyrans". Bioorganic & Medicinal Chemistry Letters 16
12 (2006): 3135-3138. http://dx.doi.org/10.1002/chin.200637123.
10.1016/j.bmcl.2006.03.064
- Cordova, I.; Leon, L. G.; Leon, F.; San Andres, L.; Luis, J. G.; Padron, J. M.. "Synthesis and antiproliferative activity
of novel sugiol beta-amino alcohol analogs". European Journal of Medicinal Chemistry 41 11 (2006): 1327-1332.
10.1016/j.ejmech.2006.06.001
- Crisostomo, F. R. P.; Padron, J. M.; Martin, T.; Villar, J.; Martin, V. S.. "A short and efficient enantiomeric synthesis
of antitumor fused tetrahydrofurans". European Journal of Organic Chemistry 8 (2006): 1910-1916.
10.1002/ejoc.200500842
- Padron, J. M.; Peters, G. J.. "Cytotoxicity of sphingoid marine compound analogs in mono- and multilayered solid tumor cell
cultures". Investigational New Drugs 24 3 (2006): 195-202.
10.1007/s10637-005-3691-5
- Padron, J. M.; Donadel, O. J.; Leon, L. G.; Martin, T.; Martin, V. S.. "Enhancement of drug cytotoxicity by silicon containing
groups". Letters in Drug Design & Discovery 3 1 (2006): 29-34.
10.2174/157018006775240944
- Guerrero, Iva N. C.; Andres, Lucia S.; Leon, Leticia G.; Machin, Ruben P.; Padron, Jose M.; Luis, Javier G.; Delgadillo, Jose.
"Abietane diterpenoids from Salvia pachyphylla and S-Clevelandii with cytotoxic activity against human cancer cell lines".
Journal of Natural Products 69 12 (2006): 1803-1805.
10.1021/np060279i
- Padrón, J.M.; Miranda, P.O.; Padrón, J.I.; Martín, V.S.. "ß'-Hydroxy-a,ß-unsaturated ketones: A new pharmacophore for the
design of anticancer drugs". Bioorganic and Medicinal Chemistry Letters 16 8 (2006): 2266-2269. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644807115&partnerID=MN8TOARS.
10.1016/j.bmcl.2006.01.023
- Carrillo, R.; León, L.G.; Martín, T.; Martín, V.S.; Padrón, J.M.. "Synthesis and antiproliferative activity of (2R,3R)-disubstituted
tetrahydropyrans". Bioorganic and Medicinal Chemistry Letters 16 23 (2006): 6135-6138. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750531635&partnerID=MN8TOARS.
10.1016/j.bmcl.2006.08.094
- Padron, J. M.; Tejedor, D.; Santos-Exposito, A.; Garcia-Tellado, F.; Martin, V. S.; Villar, J.. "Antiproliferative activity
in HL60 cells by tetrasubstituted pyrroles: a structure-activity relationship study". Bioorganic & Medicinal Chemistry
Letters 15 10 (2005): 2487-2490.
10.1016/j.bmcl.2005.03.069
- Padron, J. M.; Tejedor, D.; Santos-Exposito, A.; Garcia-Tellado, F.; Villar, J.; Martin, V. S.. "Synthesis and anti-breast
cancer activity of tetrasubstituted pyrrole derivatives". Letters in Drug Design & Discovery 2 7 (2005): 529-532.
10.2174/157018005774479122
- Donadel, O. J.; Martin, T.; Martin, V. S.; Villar, J.; Padron, J. M.. "The tert-butyl dimethyl silyl group as an enhancer
of drug cytotoxicity against human tumor cells". Bioorganic & Medicinal Chemistry Letters 15 15 (2005): 3536-3539.
10.1016/j.bmcl.2005.05.126
- "Modulation of cytotoxicity by the tert-butyl dimethyl silyl group". Annals of Oncology (2005): https://publons.com/wos-op/publon/5550727/.
- "Development of new anticancer drugs from secondary metabolites of marine origin". Journal of Biotechnology (2005):
https://publons.com/wos-op/publon/5550722/.
- "Secondary metabolites of marine origin in the development of novel anticancer agents.". Clinical Cancer Research (2005):
https://publons.com/wos-op/publon/5550719/.
- "Induction of apoptosis by fused tetrahydrofuranes". Annals of Oncology (2005): https://publons.com/wos-op/publon/19048558/.
- Al-Madhoun, A. S.; van der Wilt, C. L.; Loves, W. J. P.; Padron, J. M.; Eriksson, S.; Talianidis, I.; Peters, G. J.. "Detection
of an alternatively spliced form of deoxycytidine kinase mRNA in the 2 '-2 '-difluorodeoxycytidine (gemcitabine)-resistant
human ovarian cancer cell line AG6000". Biochemical Pharmacology 68 4 (2004): 601-609.
10.1016/j.bcp.2004.05.007
- "Inhibition of the activity of the native ¿-aminobutyric acidA receptor by metabolites of thyroid hormones: correlations with
molecular modeling studies". Brain Research (2004): https://publons.com/wos-op/publon/4260544/.
10.1016/J.BRAINRES.2003.12.043
- Lambers, M.; Beijer, F. H.; Padron, J. M.; Toth, I.; de Vries, J. G.. "Highly selective hydroformylation of the cinchona alkaloids".
Journal of Organic Chemistry 67 14 (2002): 5022-5024.
10.1021/jo0255173
- Schmieder-van de Vondervoort, L.; Bouttemy, S.; Padron, J. M.; Le Bras, J.; Muzart, J.; Alsters, P. L.. "Chromium catalyzed
oxidation of (homo-)allylic and (homo-)propargylic alcohols with sodium periodate to ketones or carboxylic acids". Synlett
2 (2002): 243-246.
UNSP 1437-2096,E;2002,0,02,0243,0246,ftx,en;G33001ST.pd
- Baragaña, B.; Blackburn, A.G.; Breccia, P.; Davis, A.P.; De Mendoza, J.; Padrón-Carrillo, J.M.; Prados, P.; et al. "Enantioselective
transport by a steroidal guanidinium receptor". Chemistry - A European Journal 8 13 (2002): 2931-2936. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037007877&partnerID=MN8TOARS.
10.1002/1521-3765(20020703)8:13<2931::AID-CHEM2931>3.0.CO;2-H
- Kokotos, G.; Constantinou-Kokotou, V.; Padrón, J.M.; Peters, G.J.; Padron, J. M.; Peters, G. J.. "Synthesis and in vitro cytotoxicity
of novel long chain busulphan analogues". Bioorganic and Medicinal Chemistry Letters 11 6 (2001): 861-863. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035953059&partnerID=MN8TOARS.
10.1016/S0960-894X(01)00084-1
- Markidis, T.; Padron, J.M.; Martin, V.S.; Peters, G.J.; Kokotos, G.. "Synthesis and in vitro cytotoxicity of long chain 2-amino
alcohols and 1,2-diamines". Anticancer Research 21 4 A (2001): 2835-2839. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035149524&partnerID=MN8TOARS.
- "Chromium catalyzed oxidations of alcohols with sodium periodate.". Abstracts of Papers of the American Chemical Society
(2001): https://publons.com/wos-op/publon/19048559/.
- Padrón, J.M.; Van Der Wilt, C.L.; Smid, K.; Smitskamp-Wilms, E.; Backus, H.H.J.; Pizao, P.E.; Giaccone, G.; et al. "The multilayered
postconfluent cell culture as a model for drug screening". Critical Reviews in Oncology/Hematology 36 2-3 (2000): 141-157.
http://www.scopus.com/inward/record.url?eid=2-s2.0-0033795717&partnerID=MN8TOARS.
10.1016/S1040-8428(00)00083-4
- Backus, H.H.J.; Pinedo, H.M.; Wouters, D.; Padrón, J.M.; Molders, N.; Van Der Wilt, C.L.; Van Groeningen, C.J.; et al. "Folate
depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates". International Journal of
Cancer 87 6 (2000): 771-778. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033845077&partnerID=MN8TOARS.
10.1002/1097-0215(20000915)87:6<771::AID-IJC2>3.0.CO;2-V
- Padrón, J.M.; Martin, V.S.; Hadjipavlou-Litina, D.; Noula, C.; Constantinou-Kokotou, V.; Peters, G.J.; Kokotos, G.; et al.
"Synthesis, in vitro cytotoxicity and in vivo anti-inflammatory activity of long chain 3-amino-1,2-diols". Bioorganic and
Medicinal Chemistry Letters 9 6 (1999): 821-826. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033594158&partnerID=MN8TOARS.
10.1016/S0960-894X(99)00084-0
- Padrón, J.M.; Van Moorsel, C.J.A.; Bergman, A.M.; Smitskamp-Wilms, E.; Van Der Wilt, C.L.; Peters, G.J.. "Selective cell kill
of the combination of gemcitabine and cisplatin in multilayered postconfluent tumor cell cultures". Anti-Cancer Drugs
10 5 (1999): 445-452. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033437203&partnerID=MN8TOARS.
10.1097/00001813-199906000-00003
- Kokotos, G.; Padron, J. M.; Martin, T.; Gibbons, W. A.; Martin, V. S.. "A general approach to the asymmetric synthesis of
unsaturated lipidic alpha-amino acids. The first synthesis of alpha-aminoarachidonic acid". Journal of Organic Chemistry
63 11 (1998): 3741-3744.
10.1021/jo9715128
- Padron, J. M.; Kokotos, G.; Martin, T.; Markidis, T.; Gibbons, W. A.; Martin, V. S.; Padrón, J.M.; et al. "Enantiospecific
synthesis of alpha-amino acid semialdehydes: a key step for the synthesis of unnatural unsaturated and saturated alpha-amino
acids". Tetrahedron-Asymmetry 9 19 (1998): 3381-3394. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032476172&partnerID=MN8TOARS.
10.1016/s0957-4166(98)00354-1
- Padron, JM; Kokotos, G; Markidis, T; Peters, GJ; Martin, VS. "Unsaturated lipidic a-amino acids derivatives, a novel class
of antisignalling agents with cytotoxic activity in vitro". Annals of Oncology (1998): https://publons.com/wos-op/publon/19048560/.
- Ramírez, M.A.; Padrón, J.M.; Palazón, J.M.; Martín, V.S.. "Stereocontrolled Synthesis of Cyclic Ethers by Intramolecular Hetero-Michael
Addition. 6. A Computational Study of the Annelation to 2,3-Disubstituted Tetrahydropyrans". Journal of Organic Chemistry
62 14 (1997): 4584-4590. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030852861&partnerID=MN8TOARS.
10.1021/jo961925t
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Ethers by Intramolecular Hetero-Michael Addition. 5. Synthesis of All Diastereoisomers of 2,3,5,6-Tetrasubstituted Tetrahydropyrans".
Journal of Organic Chemistry 62 14 (1997): 4570-4583. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030876792&partnerID=MN8TOARS.
10.1021/jo9619241
- Kokotos, G.; Padron, J. M.; Noula, C.; Gibbons, W. A.; Martin, V. S.. "A general approach to the enantiomeric synthesis of
lipidic alpha-amino acids, peptides and vicinal amino alcohols". Tetrahedron-Asymmetry 7 3 (1996): 857-866.
10.1016/0957-4166(96)00084-5
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