Identification
Personal identification
- Full name
- Ricardo António Afonso Reis
Citation names
- Afonso-Reis, Ricardo
Author identifiers
- Ciência ID
- 9410-3C26-E889
- ORCID iD
- 0000-0002-6448-058X
Knowledge fields
- Natural sciences - Biological Sciences - Molecular Biology
- Natural sciences - Biological Sciences - Cell Biology
- Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
- Medical and Health Sciences - Basic Medicine - Human Genetics
- Medical and Health Sciences - Basic Medicine - Neurosciences
- Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions
- Medical and Health Sciences - Basic Medicine - Human Genetics
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
Portuguese (Mother tongue) | |||||
English | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | |
Spanish; Castilian | Elementary (A2) | Intermediate (B1) | Elementary (A2) | Intermediate (B1) | |
French | Beginner (A1) | Beginner (A1) | Beginner (A1) | Elementary (A2) |
Education
Degree | Classification | |
---|---|---|
2023/03/01 - 2027/03/01
Ongoing
|
Ciências Biomédicas (Doutoramento)
Major in Gene therapy applied to genetic neurodegenerative disorders
Universidade do Algarve, Portugal
|
|
2020 - 2021
Concluded
|
Abordagens Experimentais em Biomedicina (Pós-Graduação)
Universidade do Algarve - Campus de Gambelas, Portugal
|
20 |
2018 - 2020
Concluded
|
Ciências Biomédicas (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
"Silencing ATXN2 through CRISPR-mediated insertion of a premature STOP codon" (THESIS/DISSERTATION)
|
18 |
2015 - 2018
Concluded
|
Ciências Biomédicas (Licenciatura)
Universidade do Algarve - Campus de Gambelas, Portugal
"Analysis of ZNF687 gene expression in different tumors using the cancer genome atlas database" (THESIS/DISSERTATION)
|
15 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2022/01/01 - Current | Researcher (Research) | Universidade do Algarve - Campus de Gambelas, Portugal |
Algarve Biomedical Center Research Institute (ABC-RI), Portugal | ||
2022/08/05 - 2022/10/31 | Visiting Researcher (Research) | University of Massachusetts Chan Medical School Horae Gene Therapy Center, United States |
2021/02/01 - 2021/10/31 | Researcher (Research) | Universidade do Algarve - Campus de Gambelas, Portugal |
Universidade do Algarve Centro de Investigação em Biomedicina, Portugal | ||
2019/01 - 2019/03 | Research Trainee (Research) | Universidade do Algarve - Campus de Gambelas, Portugal |
Universidade do Algarve Centro de Investigação em Biomedicina, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2021/09/01 - Current | Assessment of experimental therapies in pre-clinical studies of Cockayne Syndrome
#431
|
Ongoing
|
2021/01/01 - 2021/10/31 | Overexpression of the RNA-binding protein GXXXX as a therapeutic strategy to Machado-Joseph disease and other Polyglutamine
diseases
22424
Research Fellow
Universidade do Algarve Centro de Investigação em Biomedicina, Portugal
|
AFM-Téléthon
Concluded
|
Outputs
Publications
Conference abstract |
|
Conference poster |
|
Journal article |
|
Thesis / Dissertation |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2024/02/09 | CARHSP1, a stress granule component, as a potential therapeutic approach to SCA3 | SPF meeting 2024
SPF - Portuguese Society of Pharmacology (Lisbon, Portugal)
|
2021 | CRISPR/Cas9-mediated silencing of ATXN2 expression | XLXI Meeting
Portuguese Society of Pharmacology (SPF) (Lisbon, Portugal)
|
2021 | Mapping the domains of RBP-X towards mitigation of the pathological phenotype in polyglutamine disease models | XLXI Meeting
Portuguese Society of Pharmacology (SPF) (Lisbon, Portugal)
|
2021 | RBP-X protein mitigates disease traits in different mice models of polyglutamine diseases | XLXI Meeting
Portuguese Society of Pharmacology (SPF) (Lisbon, Portugal)
|
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2022/03/01 - 2022/07/31 | Generation of a HEK 293T ERCC6-knockout cell line as a Cockayne Syndrome model
Co-supervisor of Gustavo Miguel Sanches Rico
|
Ciências Biomédicas (Degree)
Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal
|
2021 - 2021/08 | Assessing CRISPR/Cas9-mediated insertion of an indel mutation in the ATXN2 gene
Co-supervisor of Raquel Costa
|
Ciências Biomédicas (Degree)
Universidade do Algarve - Campus de Gambelas, Portugal
|
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2023/10 - 2024/09 | Assessment of a gene therapy strategy for Cockayne Syndrome | Adriana Afonso Vaz |
Distinctions
Award
2023 | PhD fellowship grant FCT 2022.09679.BD
Fundação para a Ciência e a Tecnologia, Portugal
|