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Philip Gerrish. Published 30 articles in journals. In their professional activities interacted with 59 collaborator(s) co-authorship of scientific papers.
Identificação

Identificação pessoal

Nome completo
Philip Gerrish

Nomes de citação

  • Gerrish, Philip

Identificadores de autor

Ciência ID
0B1E-A4EE-ECA2
ORCID iD
0000-0001-6393-0553

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia da Evolução das Espécies
  • Ciências Exatas - Matemática - Matemática Aplicada

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês (Idioma materno)
Espanhol; Castelhano Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Português Utilizador independente (B2) Utilizador proficiente (C1) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2)
Francês Utilizador independente (B1) Utilizador independente (B2) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B2)
Formação
Grau Classificação
1994/08/25 - 1998/12/18
Concluído
Zoology (Doctor of Philosophy)
Especialização em Ecology and Evolutionary Biology
Michigan State University - Lansing Community Campus, Estados Unidos
"Dynamics of mutation and selection in asexual populations" (TESE/DISSERTAÇÃO)
1992/08/20 - 1997/12/15
Concluído
Mathematics (Master)
Especialização em Probability Theory
Michigan State University - Lansing Community Campus, Estados Unidos
1992/08/20 - 1994/05/15
Concluído
BioSystems Engineering (Master)
Michigan State University - Lansing Community Campus, Estados Unidos
1984/09/07 - 1988/05/20
Concluído
Physics (Licence)
Especialização em physics
Hope College, Estados Unidos
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2015/08/15 - Atual Investigador (Investigação) Georgia Institute of Technology, Estados Unidos
2008/08/20 - 2015/07/31 Investigador principal (carreira) (Investigação) University of New Mexico, Estados Unidos
2004/09/15 - 2008/08/31 Investigador visitante (Investigação) Los Alamos National Laboratory, Estados Unidos
2000/05/01 - 2003/04/30 Pós-doutorado (Investigação) Los Alamos National Laboratory, Estados Unidos
Projetos

Bolsa

Designação Financiadores
2018/01/15 - 2019/12/10 Assessing the potential of recombination inhibitors as antimicrobial agents
CAPES/MEC
Investigador responsável
Georgia Institute of Technology, Estados Unidos

Universidade Federal de São Paulo, Brasil
Fulbright Association
Em curso
2014/08/20 - 2019/12/10 Reliving the past: Experimental evolution of major transitions in the history of life.
NNA15BB04A
Outra
Georgia Institute of Technology, Estados Unidos
NASA
Em curso
2012/09/01 - 2014/08/31 Assessing a novel hypothesis that B-cell error catastrophe can cause germinal center termination.
CETI/UNM
Investigador responsável
University of New Mexico, Estados Unidos
National Institutes of Health
Concluído
2011/09/01 - 2013/08/31 Mutation rate catastrophe (continuation)
GM079843-SUPPL
Investigador responsável
University of New Mexico, Estados Unidos
National Institutes of Health
Concluído
2008/08/15 - 2012/08/14 Mutation rate catastrophe: testing a novel theory for extinction of clonal organisms
R01 GM079843-01
Investigador responsável
University of New Mexico, Estados Unidos
National Institutes of Health
Concluído
Produções

Publicações

Artigo em conferência
  1. Gerrish, Philip; Ferreira, Claudia. "Mutation rate and the maintenance of cooperation: a parsimonious model of somatic evolution and oncogenic transitions". 2010.
    Publicado
Artigo em revista
  1. Philip J Gerrish; Claudia P Ferreira. "A thermodynamic limit constrains complexity and primitive social function". International Journal of Astrobiology (2018): 1-7. https://doi.org/10.1017/S1473550418000149.
    10.1017/S1473550418000149
  2. Pénisson, Sophie; Singh, Tanya; Sniegowski, Paul; Gerrish, Philip. "Dynamics and Fate of Beneficial Mutations Under Lineage Contamination by Linked Deleterious Mutations". Genetics 205 3 (2017): 1305-1318. http://dx.doi.org/10.1534/genetics.116.194597.
    10.1534/genetics.116.194597
  3. Gerrish, P.J.; Colato, A.; Sniegowski, P.D.. "Genomic mutation rates that neutralize adaptive evolution and natural selection". Journal of the Royal Society Interface 10 85 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84880075500&partnerID=MN8TOARS.
    10.1098/rsif.2013.0329
  4. Pénisson, S.; Sniegowski, P.D.; Colato, A.; Gerrish, P.J.. "Lineage dynamics and mutation-selection balance in non-adapting asexual populations". Journal of Statistical Mechanics: Theory and Experiment 2013 1 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84874460802&partnerID=MN8TOARS.
    10.1088/1742-5468/2013/01/P01013
  5. Sprouffske, K.; Merlo, L.M.F.; Gerrish, P.J.; Maley, C.C.; Sniegowski, P.D.. "Cancer in light of experimental evolution". Current Biology 22 17 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84866163568&partnerID=MN8TOARS.
    10.1016/j.cub.2012.06.065
  6. de la Iglesia, F.; Martínez, F.; Hillung, J.; Cuevas, J.M.; Gerrish, P.J.; Daròs, J.-A.; Elena, S.F.. "Luria-Delbrück estimation of turnip mosaic virus mutation rate in vivo". Journal of Virology 86 6 (2012): 3386-3388. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857934175&partnerID=MN8TOARS.
    10.1128/JVI.06909-11
  7. Gerrish, P.J.; Sniegowski, P.D.. "Real time forecasting of near-future evolution". Journal of the Royal Society Interface 9 74 (2012): 2268-2278. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866184100&partnerID=MN8TOARS.
    10.1098/rsif.2012.0119
  8. Gentile, C.F.; Yu, S.-C.; Serrano, S.A.; Gerrish, P.J.; Sniegowski, P.D.. "Competition between high-and higher-mutating strains of Escherichia coli". Biology Letters 7 3 (2011): 422-424. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960838115&partnerID=MN8TOARS.
    10.1098/rsbl.2010.1036
  9. Gerrish, P.J.; Sniegowski, P.D.. "Adding dynamical sufficiency to Fisher's fundamental theorem of natural selection". AIP Conference Proceedings 1389 (2011): 1260-1262. http://www.scopus.com/inward/record.url?eid=2-s2.0-81855216225&partnerID=MN8TOARS.
    10.1063/1.3637846
  10. Sniegowski, P.D.; Gerrish, P.J.. "Beneficial mutations and the dynamics of adaptation in asexual populations". Philosophical Transactions of the Royal Society B: Biological Sciences 365 1544 (2010): 1255-1263. http://www.scopus.com/inward/record.url?eid=2-s2.0-77951593683&partnerID=MN8TOARS.
    10.1098/rstb.2009.0290
  11. Gerrish, P.J.. "Some observations about the nearest-neighbor model of the error threshold". AIP Conference Proceedings 1168 (2009): 1564-1568. http://www.scopus.com/inward/record.url?eid=2-s2.0-70450174911&partnerID=MN8TOARS.
    10.1063/1.3241401
  12. Gerrish, P.. "A simple formula for obtaining markedly improved mutation rate estimates". Genetics 180 3 (2008): 1773-1778. http://www.scopus.com/inward/record.url?eid=2-s2.0-59449104244&partnerID=MN8TOARS.
    10.1534/genetics.108.091777
  13. Gerrish, P.J.; Colato, A.; Perelson, A.S.; Sniegowski, P.D.. "Complete genetic linkage can subvert natural selection". Proceedings of the National Academy of Sciences of the United States of America 104 15 (2007): 6266-6271. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547511450&partnerID=MN8TOARS.
    10.1073/pnas.0607280104
  14. Gerrish, P.J.; García-Lerma, J.G.. "Mutation rate and the efficacy of antimicrobial drug treatment". Lancet Infectious Diseases 3 1 (2003): 28-32. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037223513&partnerID=MN8TOARS.
    10.1016/S1473-3099(03)00485-7
  15. Burr, T.L.; Gattiker, J.R.; Gerrish, P.J.. "An investigation of error sources and their impact in estimating the time to the most recent ancestor of spatially and temporally distributed HIV sequences". Statistics in Medicine 22 9 (2003): 1495-1516. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037687794&partnerID=MN8TOARS.
    10.1002/sim.1508
  16. Kalish, Marcia L.; Korber, Bette T.; Pillai, Satish; Robbins, Kenneth E.; Leo, Yee Sin; Saekhou, Ae; Verghese, Iris; et al. "The Sequential Introduction of HIV-1 Subtype B and CRF01AE in Singapore by Sexual Transmission: Accelerated V3 Region Evolution in a Subpopulation of Asian CRF01 Viruses". Virology 304 2 (2002): 311-329. http://dx.doi.org/10.1006/viro.2002.1691.
    10.1006/viro.2002.1691
  17. Rozen, D.E.; De Visser, J.A.G.M.; Gerrish, P.J.. "Fitness effects of fixed beneficial mutations in microbial populations". Current Biology 12 12 (2002): 1040-1045. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037172667&partnerID=MN8TOARS.
    10.1016/S0960-9822(02)00896-5
  18. Kalish, M.L.; Korber, B.T.; Pillai, S.; Robbins, K.E.; Leo, Y.S.; Saekhou, A.; Verghese, I.; et al. "The sequential introduction of HIV-1 subtype B and CRF01_AE in Singapore by sexual transmission: Accelerated V3 region evolution in a subpopulation of Asian CRF01 viruses". Virology 304 2 (2002): 311-329. http://www.scopus.com/inward/record.url?eid=2-s2.0-12244263559&partnerID=MN8TOARS.
    10.1006/viro.2002.1691
  19. Gerrish, P.. "Computational biology: Evolution plays dice". Nature 420 6917 (2002): 756-757. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037180724&partnerID=MN8TOARS.
    10.1038/420756a
  20. Johnson, T.; Gerrish, P.J.. "The fixation probability of a beneficial allele in a population dividing by binary fission". Genetica 115 3 (2002): 283-287. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036669559&partnerID=MN8TOARS.
    10.1023/A:1020687416478
  21. Wahl, L.M.; Gerrish, P.J.; Saika-Voivod, I.. "Evaluating the impact of population bottlenecks in experimental evolution". Genetics 162 2 (2002): 961-971. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036811710&partnerID=MN8TOARS.
  22. Gerrish, P.. "The rhythm of microbial adaptation (Nature (2001) 413 (299-302))". Nature 414 6865 (2001): http://www.scopus.com/inward/record.url?eid=2-s2.0-0035856906&partnerID=MN8TOARS.
    10.1038/414779a
  23. Gerrish, P.. "The rhythm of microbial adaptation". Nature 413 6853 (2001): 299-302. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035921922&partnerID=MN8TOARS.
    10.1038/35095046
  24. Wahl, L.M.; Gerrish, P.J.. "The probability that beneficial mutations are lost in populations with periodic bottlenecks". Evolution 55 12 (2001): 2606-2610. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035544558&partnerID=MN8TOARS.
  25. Webby, R.J.; Swenson, S.L.; Krauss, S.L.; Gerrish, P.J.; Goyal, S.M.; Webster, R.G.. "Evolution of swine H3N2 influenza viruses in the United States". Journal of Virology 74 18 (2000): 8243-8251. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033850375&partnerID=MN8TOARS.
    10.1128/JVI.74.18.8243-8251.2000
  26. Sniegowski, P.D.; Gerrish, P.J.; Johnson, T.; Shaver, A.. "The evolution of mutation rates: Separating causes from consequences". BioEssays 22 12 (2000): 1057-1066. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034542564&partnerID=MN8TOARS.
    10.1002/1521-1878(200012)22:12<1057::AID-BIES3>3.0.CO;2-W
  27. Garcia-Lerma, J.G.; Gerrish, P.J.; Wright, A.C.; Qari, S.H.; Heneine, W.. "Evidence of a role for the Q151L mutation and the viral background in development of multiple dideoxynucleoside-resistant human immunodeficiency virus type 1". Journal of Virology 74 20 (2000): 9339-9346. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033819048&partnerID=MN8TOARS.
    10.1128/JVI.74.20.9339-9346.2000
  28. De Visser, J.A.G.M.; Zeyl, C.W.; Gerrish, P.J.; Blanchard, J.L.; Lenski, R.E.. "Diminishing returns from mutation supply rate in asexual populations". Science 283 5400 (1999): 404-406. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033555421&partnerID=MN8TOARS.
    10.1126/science.283.5400.404
  29. Miralles, R.; Gerrish, P.J.; Moya, A.; Elena, S.F.. "Clonal interference and the evolution of RNA viruses". Science 285 5434 (1999): 1745-1747. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033543602&partnerID=MN8TOARS.
    10.1126/science.285.5434.1745
  30. Gerrish, P.J.; Lenski, R.E.. "The fate of competing beneficial mutations in an asexual population". Genetica 102-103 (1998): 127-144. http://www.scopus.com/inward/record.url?eid=2-s2.0-2542583245&partnerID=MN8TOARS.
  31. Lenski, R.E.; Mongold, J.A.; Sniegowski, P.D.; Travisano, M.; Vasi, F.; Gerrish, P.J.; Schmidt, T.M.. "Evolution of competitive fitness in experimental populations of E. coli: What makes one genotype a better competitor than another?". Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology 73 1 (1998): 35-47. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031966353&partnerID=MN8TOARS.
    10.1023/A:1000675521611
  32. Sniegowski, P.D.; Gerrish, P.J.; Lenski, R.E.. "Evolution of high mutation rates in experimental populations of E. coli". Nature 387 6634 (1997): 703-705. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030620273&partnerID=MN8TOARS.
    10.1038/42701
Capítulo de livro
  1. Gerrish, Philip; Hengartner, Nicholas. "Inferring the distribution of fitness effects (DFE) of newly-arising mutations using samples taken from evolving populations in real time.". In Algorithms for Computational Biology, editado por Figueiredo, C; Martin-Vide, C; Pratas, D; Vega-Rodriguez, MA. New York, Estados Unidos: Springer, 2017.
    Publicado
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2018/11 The rhythm of microbial adaptation, revisited. Ancestral Lines
University of Frankfurt (Frankfurt, Alemanha)
2018/10 Is there sex on other planets? RCM2 Mathematics seminar
University of Bielefeld (Bielefeld, Alemanha)
2018/04/07 On the inevitability of recombination Biology department seminar series
University of Grenoble (Grenoble, França)
2018/02 A thermodynamic limit constrains the evolution of cooperation and complexity CEID seminar
University of Georgia (Athens, Estados Unidos)
2017/11 Is there sex on other planets? An astrobiologist weighs in on the enduring problem of explaining the evolution of sex and recombination PBEE colloquium
Emory University (Atlanta, Estados Unidos)
2017/11 Dynamics and fate of beneficial mutations under lineage contamination Ancestral Lines
University of Frankfurt / Mathematics (Frankfurt, Alemanha)
2017/07 Some universal properties of adaptation under linkage Center for Phylogenomics seminar series
University of Vigo (Vigo, Espanha)
2017/07 On the inevitability of recombination Mathematics Departmental seminar
University of Grenoble (Grenoble, França)
2017/06 An overview of NASA/NAI/CAN7 research and promising collaborative potential with CAB CAB seminar
Centro de Astrobiologia (Alcala de Henares, Espanha)
2017/06 Inferring the distribution of mutational effects (DFE) from data taken at the population level in real time 4th International Conference on Algorithms for Computational Biology, AlCoB 2017
University of Aveiro (Aveiro, Portugal)
2017/06 Effects of lineage contamination on adaptive evolution NASA Astrobiology Science Conference, AbSciCon 2017
NASA (Tucson, Estados Unidos)
2016/11 Forecasting the near-future course of evolution in real time Mind the Gap 5: Bridging the gap between theoretical and empirical population genetics
University of Vienna (Vienna, Áustria)
2015/10 Probabilistic features of natural selection suggest the evolution of recombination is inevitable Probabilistic Models in Biology
CONACYT / UNAM (Playa del Carmen, México)
2015/10 Forecasting evolution Institute seminar series
Instituto de Ecologia (Xalapa, México)
2015/06 Forecasting the near-future course of evolution NASA Astrobiology Science Conference, AbSciCon 2015
NASA (Chicago, Estados Unidos)
2013/02 ------- MANY MANY MORE INVITED TALKS ------ [Autocomplete on web form made it virtually unusable and virtually impossible to complete this list] conference title