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From 2003 to 2007, Fábio Fernandes did his PhD on the application of biophysical methods to the study of protein-lipid and protein-drug interactions at the Instituto Superior Técnico (Lisbon) under the supervision of Dr. Manuel Prieto and Dr. Luís M. Loura. From 2007-2010 he worked as a postdoc with Prof. Dr. Erwin Neher in the Membrane Biophysics group at the Max Planck Institute for Biophysical Chemistry, Göttingen (Germany). From 2010-2016 he worked as a Senior Postdoc at the Centro de Química Física Molecular and Institute of Nanosciences and Nanotechnologies in Instituto Superior Técnico (IST), Lisbon. In 2016, he joined the Research Unit on Applied Molecular Biosciences (UCIBIO@REQUIMTE) of the Universidade Nova de Lisboa as an Auxiliary Researcher. Since 2017, he is a Fundação para a Ciência e a Tecnologia (FCT) Researcher at IST.
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Identificação

Identificação pessoal

Nome completo
FABIO FERNANDES

Nomes de citação

  • FERNANDES, FABIO

Identificadores de autor

Ciência ID
1116-640D-A76A
ORCID iD
0000-0001-9112-265X

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2007
Concluído
 Química (Doutoramento)
Especialização em Sem especialidade
Universidade Técnica de Lisboa, Portugal
"Biophysical Studies of Membrane Proreins/peptides. Interaction with Lipids and Drugs" (TESE/DISSERTAÇÃO)
2001
Concluído
 Biochemistry (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Characterisation of the photophysical and membrane partition properties of a fluorescent molecular probe: 1-caproyl-2-[6-[(7-nitrobenz-2-oxa-1,3-diazo-4-yl)amino]caproil]phophatidylcholine" (TESE/DISSERTAÇÃO)
 15
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2016/12/01 - Atual Investigador principal (carreira) (Investigação) Universidade de Lisboa Instituto Superior Técnico, Portugal
2016/06/01 - 2016/11/30 Investigador Auxiliar (carreira) (Investigação) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2010/03/01 - 2016/05/31 Pós-doutorado (Investigação) Universidade de Lisboa Instituto Superior Técnico, Portugal
2007/10/01 - 2010/03/31 Pós-doutorado (Investigação) Max-Planck-Institut für biophysikalische Chemie, Alemanha
2003/09/01 - 2007/09/17 Investigador (Investigação) Universidade de Lisboa Instituto Superior Técnico, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/05/01 - Atual Professor Auxiliar (Docente Universitário) Universidade de Lisboa Instituto Superior Técnico, Portugal
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/09/01 - 2019/04/01 Professor Auxiliar Convidado (Docente Universitário) Universidade de Lisboa Instituto Superior Técnico, Portugal
2018 - 2019 Professor Auxiliar Convidado (Docente Universitário) Universidade de Lisboa, Portugal
Projetos

Bolsa

Designação Financiadores
2023 - 2024 Next generation of antibiofilm agents: Multivalent dendrimers with antimicrobial and biofilm disruption activity (2022.03627.PTDC)
2022.03627.PTDC
Co-Investigador Responsável (Co-IR)
Fundação para a Ciência e Tecnologia
2022/01/17 - 2023/07/16 Engineering broad-spectrum defensosomes for a bacterial antivirulence therapeutic strategy
EXPL/BTM-MAT/0910/2021
Orientador
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/08 - 2021/07 Engineering of Smart Exosomes for Amyloid-beta Clearance in Alzheimer disease.
PTDC/BTM-SAL/31057/2017
 Funding by FCT and Portugal2020
2019/02/03 - 2021/03/01 NeuroAbetaClear: Development of a scalable manufacturing process for therapeutic human mesenchymal stem/stromal cell-derived exosomes
LISBOA-01-0145-FEDER-031057
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
 Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
Concluído
2015/10 - 2018/09 Lipid Oxidation in membrane and cell Biophysics: From Functional nanosensors to the impact on amyloid formation. Application of advanced fluorescence, X-Ray scattering and microscopy Techniques
Provided by PTCRIS: 147655
 Fundação para a Ciência e a Tecnologia, I.P.
2012/03 - 2015/02 Interaction of bile acids with lipid membranes: creating a shield or bursting the bubble.
Provided by PTCRIS: 119494
119494
 Fundação para a Ciência e a Tecnologia, I.P.
2011/02 - 2014/07 Relationship between PI(4,5)P2 compartmentalization and palmitoylated synaptic proteins in membrane model systems and in the plasma membrane of neuron and non-neuron like cells.
112067
Provided by PTCRIS: 112067
 Fundação para a Ciência e a Tecnologia, I.P.
2007/10 - 2010/09 Lipid Rafts, Ceramide, and Human Immunodeficiency Virus: a Biophysical Connection
Provided by PTCRIS: 68151
68151
 Fundação para a Ciência e a Tecnologia, I.P.
2007/01 - 2009/03 Molecular interactions in lipid raft models: from lipid phases to membrane protein organization
Provided by PTCRIS: 82384
82384
 Fundação para a Ciência e a Tecnologia, I.P.
2005/06 - 2008/05 Molecular mechanism of inhibition of the vacuolar H+-ATPase of osteoclasts by potential antiosteporotic drugs
57114
Provided by PTCRIS: 57114
 Fundação para a Ciência e a Tecnologia, I.P.

Projeto

Designação Financiadores
2023/06/01 - 2024/05/31 Mechanistic insights into adaptation and increased robustness to acetic acid and other weak acids toxicity in yeasts
2022.01501.PTDC
10.54499/2022.01501.PTDC
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018/10/01 - 2022/09/30 Organoid Engineering for Production of 3D Cardiovascular Microtissues from Human Induced Pluripotent Stem Cells for Cardiotoxicity Assays
PTDC/EMD-TLM/29728/2017
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018/09/01 - 2022/08/31 Delayed Fluorescence Nanomaterials for Imaging and Sensing
PTDC/QUI-QFI/32007/2017
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2017/01/01 - 2021/06/30 PRECISION ONCOLOGY BY INNOVATIVE THERAPIES AND TECHNOLOGIES
SAICTPAC/0019/2015
Universidade de Lisboa Faculdade de Farmácia, Portugal

Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

Instituto Politécnico de Leiria, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2017/01/15 - 2020/01/14 Lipid Oxidation in membrane and cell Biophysics: From Functional nanosensors to the impact on amyloid formation. Application of advanced fluorescence, X-Ray scattering and microscopy Techniques
FAPESP/20107/2014
Universidade de Lisboa Centro de Química-Física Molecular, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de São Paulo Instituto de Física, Brasil
Fundação para a Ciência e a Tecnologia
Concluído
2016/12/01 - 2019/04/30 Structural determinants for compartmentalization of phosphoinositides: From nanoscale molecular organization to cellular events.
IF/00386/2015/CP1272/CT0010
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2013/06/01 - 2016/11/30 MULTIFUNCTIONAL NANOMATERIALS FOR FLUORESCENCE IMAGING AND SENSING
RECI/CTM-POL/0342/2012
Universidade de Lisboa Centro de Química-Física Molecular, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2016/04/01 - 2016/05/31 Phosphoinositol structure and compartmentalization. Bridging nanoscale molecular organization and cell function.
SFRH/BPD/105651/2015
 Fundação para a Ciência e a Tecnologia
Concluído
2012/03/01 - 2015/08/31 Interaction of bile acids with lipid membranes: creating a shield or bursting the bubble.
PTDC/QUI-BIQ/119494/2010
Universidade de Lisboa Centro de Química-Física Molecular, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2011/02/01 - 2014/07/31 Relationship between PI4,5P2 compartmentalization and palmitoylated synaptic proteins in membrane model systems and in the plasma membrane of neuron and non-neuron like cells.
PTDC/QUI-BIQ/112067/2009
Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade de Lisboa Centro de Química-Física Molecular, Portugal

Universidade de Évora, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2008/04/01 - 2010/03/31 DETECTING CONFORMATIONAL CHANGES OF MUNC13 DURING VESICLE PRIMING AND EXOCYTOSIS BY FRET
SFRH/BPD/40403/2007
 Fundação para a Ciência e a Tecnologia
Concluído
2003/10/01 - 2007/09/30 ESTUDO DE PROTEÍNAS MEMBRANARES EM SISTEMAS MODELO DE BIOMEMBRANAS. CARACTERIZAÇÃO DAS INTERACÇÕES PROTEÍNA-PROTEÍNA E PROTEÍNA-LÍPIDO POR TÉCNICAS DE FLUORESCÊNCIA
SFRH/BD/14282/2003
 Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em revista
  1. Diogo Gonçalves; Sandra N. Pinto; Fábio Fernandes. "Extracellular Vesicles and Infection: From Hijacked Machinery to Therapeutic Tools". Pharmaceutics (2023): https://doi.org/10.3390/pharmaceutics15061738.
    10.3390/pharmaceutics15061738
  2. Tiago P. Dias; Sandra N. Pinto; Sandra Carvalho; Tiago G. Fernandes; Fábio Fernandes; Maria Margarida Diogo; Maria C. Peleteiro; Manuel Prieto; Joaquim M. S. Cabral. "Cost-Effective Mechanical Aggregation of Cardiac Progenitors and Encapsulation in Matrigel Support Self-Organization in a Dynamic Culture Environment". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms232415785.
    10.3390/ijms232415785
  3. Tiago P. Dias; Tânia Baltazar; Sandra N. Pinto; Tiago G. Fernandes; Fábio Fernandes; Maria Margarida Diogo; Manuel Prieto; Joaquim M. S. Cabral; Ren-Ke Li. "Xeno-Free Integrated Platform for Robust Production of Cardiomyocyte Sheets from hiPSCs". Stem Cells International (2022): https://doi.org/10.1155/2022/4542719.
    10.1155/2022/4542719
  4. Sara B Salazar; Maria Joana F Pinheiro; Danielle Sotti-Novais; Ana R Soares; Maria M Lopes; Teresa Ferreira; Vitória Rodrigues; et al. "Disclosing azole resistance mechanisms in resistant Candida glabrata strains encoding wild-type or gain-of-function CgPDR1 alleles through comparative genomics and transcriptomics". G3 Genes|Genomes|Genetics (2022): https://doi.org/10.1093/g3journal/jkac110.
    10.1093/g3journal/jkac110
  5. Luís Borges-Araújo; Marina E. Monteiro; Dalila Mil-Homens; Nuno Bernardes; Maria J. Sarmento; Ana Coutinho; Manuel Prieto; Fábio Fernandes. "Impact of Ca2+-Induced PI(4,5)P2 Clusters on PH-YFP Organization and Protein-Protein Interactions". Biomolecules (2022): https://doi.org/10.3390/biom12070912.
    10.3390/biom12070912
  6. Ricardo A. Ribeiro; Cláudia P. Godinho; Miguel V. Vitorino; Tiago T. Robalo; Fábio Fernandes; Mário S. Rodrigues; Isabel Sá-Correia. "Crosstalk between Yeast Cell Plasma Membrane Ergosterol Content and Cell Wall Stiffness under Acetic Acid Stress Involving Pdr18". Journal of Fungi 8 2 (2022): 103-103. https://doi.org/10.3390/jof8020103.
    10.3390/jof8020103
  7. Silvia Baldo; Patrícia Antunes; João Falcão Felicidade; Fábio M. F. Santos; Jesús F. Arteaga; Fábio Fernandes; Uwe Pischel; Sandra N. Pinto; Pedro M. P. Gois. "The BASHY Platform Enables the Assembly of a Fluorescent Bortezomib–GV1001 Conjugate". ACS Medicinal Chemistry Letters (2022): https://doi.org/10.1021/acsmedchemlett.1c00615.
    10.1021/acsmedchemlett.1c00615
  8. Luís Borges-Araújo; Marco M. Domingues; Alexander Fedorov; Nuno C. Santos; Manuel N. Melo; Fábio Fernandes. "Acyl-chain saturation regulates the order of phosphatidylinositol 4,5-bisphosphate nanodomains". Communications Chemistry (2021): https://doi.org/10.1038/s42004-021-00603-1.
    10.1038/s42004-021-00603-1
  9. "Yeast adaptive response to acetic acid stress involves structural alterations and increased stiffness of the cell wall". Scientific Reports 11 1 (2021): http://dx.doi.org/10.1038/s41598-021-92069-3.
    10.1038/s41598-021-92069-3
  10. Maria J. Sarmento; Luís Borges-Araújo; Sandra N. Pinto; Nuno Bernardes; Joana C. Ricardo; Ana Coutinho; Manuel Prieto; Fábio Fernandes. "Quantitative FRET Microscopy Reveals a Crucial Role of Cytoskeleton in Promoting PI(4,5)P2 Confinement". International Journal of Molecular Sciences (2021): https://doi.org/10.3390/ijms222111727.
    10.3390/ijms222111727
  11. Ana Rita Cebola Garizo; Lígia Fonseca Coelho; Sandra Pinto; Tiago P. Dias; Fabio Fernandes; Nuno Bernardes; Fialho AM. "The Azurin-Derived Peptide CT-p19LC Exhibits Membrane-Active Properties and Induces Cancer Cell Death". Biomedicines (2021): https://www.mdpi.com/2227-9059/9/9/1194.
    10.3390/biomedicines9091194
  12. Borges-Araújo, Luis; Domingues, Marco; A.A. Fedorov, ; Nuno C. Santos; Manuel N. Melo; FERNANDES, FABIO. Autor correspondente: FERNANDES, FABIO. "Acyl-chain saturation regulates the order of phosphatidylinositol 4,5-biphosphate nanodomains". Communications chemistry 4 1 (2021): 164. https://DOI.org/10.1038/s42004-021-00603-.
    Publicado • DOI:10.1038/s42004-021-00603-1
  13. Borges-Araújo, Luís; Fernandes, Fabio. "Structure and Lateral Organization of Phosphatidylinositol 4,5-bisphosphate". Molecules 25 17 (2020): 3885. http://dx.doi.org/10.3390/molecules25173885.
    10.3390/molecules25173885
  14. FERNANDES, FABIO. "Engineering Boron Hot Spots for the Site-Selective Installation of Iminoboronates on Peptide Chains". Chemistry – A European Journal (2020): http://dx.doi.org/10.1002/chem.202002675.
    10.1002/chem.202002675
  15. FERNANDES, FABIO. "Silica nanoparticles with thermally activated delayed fluorescence for live cell imaging". Materials Science and Engineering: C (2020): http://dx.doi.org/10.1016/j.msec.2019.110528.
    10.1016/j.msec.2019.110528
  16. FERNANDES, FABIO. "The mechanism of action of pepR, a viral-derived peptide, against Staphylococcus aureus biofilms". Journal of Antimicrobial Chemotherapy (2019): http://dx.doi.org/10.1093/jac/dkz223.
    10.1093/jac/dkz223
  17. Nathalie T. Reichmann; Andreia C. Tavares; Bruno M. Saraiva; Ambre Jousselin; Patricia Reed; Ana R. Pereira; João M. Monteiro; et al. "SEDS–bPBP pairs direct lateral and septal peptidoglycan synthesis in Staphylococcus aureus". Nature Microbiology 4 8 (2019): 1368-1377. https://doi.org/10.1038/s41564-019-0437-2.
    10.1038/s41564-019-0437-2
  18. Nuno Bernardes; Ana Rita Garizo; Sandra N. Pinto; Bernardo Caniço; Catarina Perdigão; Fábio Fernandes; Arsenio M. Fialho. "Azurin interaction with the lipid raft components ganglioside GM-1 and caveolin-1 increases membrane fluidity and sensitivity to anti-cancer drugs". Cell Cycle 17 13 (2018): 1649-1666. https://doi.org/10.1080/15384101.2018.1489178.
    10.1080/15384101.2018.1489178
  19. Cláudia P. Godinho; Catarina S. Prata; Sandra N. Pinto; Carlos Cardoso; Narcisa M. Bandarra; Fábio Fernandes; Isabel Sá-Correia. "Pdr18 is involved in yeast response to acetic acid stress counteracting the decrease of plasma membrane ergosterol content and order". Scientific Reports 8 1 (2018): https://doi.org/10.1038%2Fs41598-018-26128-7.
    10.1038/s41598-018-26128-7
  20. FERNANDES, FABIO. "Staphylococcus aureus haem biosynthesis and acquisition pathways are linked through haem monooxygenase IsdG". Molecular microbiology (2018): https://doi.org/10.1111/mmi.14060.
    10.1111/mmi.14060
  21. T. P. T. Dao; F. Fernandes; M. Fauquignon; E. Ibarboure; M. Prieto; J. F. Le Meins. "The combination of block copolymers and phospholipids to form giant hybrid unilamellar vesicles (GHUVs) does not systematically lead to “intermediate” membrane properties". Soft Matter (2018): https://doi.org/10.1039/C8SM00547H.
    10.1039/C8SM00547H
  22. Dias, Tiago P.; Pinto, Sandra N.; Santos, Juliana I.; Fernandes, Tiago G.; Fernandes, Fabio; Diogo, Maria Margarida; Prieto, Manuel; Cabral, Joaquim M. S.. "Biophysical study of human induced Pluripotent Stem Cell-Derived cardiomyocyte structural maturation during long-term culture". Biochemical and Biophysical Research Communications 499 3 (2018): 611-617. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000431287700034&KeyUID=WOS:000431287700034.
    10.1016/j.bbrc.2018.03.198
  23. T.P.T. Dao; M. Fauquignon; F. Fernandes; E. Ibarboure; A. Vax; M. Prieto; J.F.Le Meins. "MEMBRANE PROPERTIES OF GIANT POLYMER AND LIPID VESICLES OBTAINED BY ELECTROFORMATION AND PVA GEL-ASSISTED HYDRATION METHODS". Colloids and Surfaces A: Physicochemical and Engineering Aspects (2017): https://doi.org/10.1016%2Fj.colsurfa.2017.09.005.
    10.1016/j.colsurfa.2017.09.005
  24. Maria J. Sarmento; Ana Coutinho; Alexander A. Fedorov; Manuel Prieto; Fabio Fernandes. "Membrane order is a key regulator of divalent cation-induced clustering of PI(3,5)P2 and PI(4,5)P2". Langmuir (2017): https://doi.org/10.1021%2Facs.langmuir.7b00666.
    10.1021/acs.langmuir.7b00666
  25. João P. Leal; Mani Outis; Maria H. Casimiro; Luis M. Ferreira; Fábio Fernandes; Bernardo Monteiro; César A. T. Laia; Cláudia C. L. Pereira. "A Case of Self-Organization in Highly Emissive EuIII Ionic Liquids". European Journal of Inorganic Chemistry 2017 28 (2017): 3429-3434. https://doi.org/10.1002%2Fejic.201700649.
    10.1002/ejic.201700649
  26. T. P. Tuyen Dao; A. Brûlet; F. Fernandes; M. Er-Rafik; K. Ferji; R. Schweins; J.-P. Chapel; et al. "Mixing Block Copolymers with Phospholipids at the Nanoscale: From Hybrid Polymer/Lipid Wormlike Micelles to Vesicles Presenting Lipid Nanodomains". Langmuir (2017): https://doi.org/10.1021%2Facs.langmuir.6b04478.
    10.1021/acs.langmuir.6b04478
  27. Diana P. Ferreira; David S. Conceição; F. Fernandes; T. Sousa; Ricardo C. Calhelha; Isabel C. F. R. Ferreira; Paulo F. Santos; L. F. Vieira Ferreira. "Characterization of a Squaraine/Chitosan System for Photodynamic Therapy of Cancer". J. Phys. Chem. B 120 7 (2016): 1212-1220. http://dx.doi.org/10.1021/acs.jpcb.5b11604.
    10.1021/acs.jpcb.5b11604
  28. Dao, Thi Phuong Tuyen; Fernandes, Fabio; Ibarboure, Emmanuel; Ferji, Khalid; Prieto, Manuel; Sandre, Olivier; Le Meins, Jean-Francois. "Modulation of phase separation at the micron scale and nanoscale in giant polymer/lipid hybrid unilamellar vesicles (GHUVs).". Soft matter (2016): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:27991638&KeyUID=MEDLINE:27991638.
  29. Bernardes, Nuno; Abreu, Sofia; Carvalho, Filomena A.; Fernandes, Fábio; Santos, Nuno C.; Fialho, Arsénio M.. "Modulation of membrane properties of lung cancer cells by azurin enhances the sensitivity to EGFR-targeted therapy and decreased ß1 integrin-mediated adhesion". Cell Cycle 15 11 (2016): 1415-1424. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000378726600011&KeyUID=WOS:000378726600011.
    10.1080/15384101.2016.1172147
  30. Sarmento, M. J.; Pinto, S. N.; Coutinho, A.; Prieto, M.; Fernandes, F.. "Accurate quantification of inter-domain partition coefficients in GUVs exhibiting lipid phase coexistence". RSC Advances 6 71 (2016): 66641-66649.
    10.1039/C6RA13170K
  31. T. P. Tuyen Dao; F. Fernandes; M. Er-Rafik; R. Salva; M. Schmutz; A. Brûlet; M. Prieto; O. Sandre; J.-F. Le Meins. "Phase Separation and Nanodomain Formation in Hybrid Polymer/Lipid Vesicles". ACS Macro Lett. 4 2 (2015): 182-186. http://dx.doi.org/10.1021/mz500748f.
    10.1021/mz500748f
  32. Ferreira AS; Silva IN; Fernandes F; Pilkington R; Callaghan M; McClean S; Moreira LM. "The Tyrosine Kinase BceF and the Phosphotyrosine Phosphatase BceD of Burkholderia contaminans Are Required for Efficient Invasion and Epithelial Disruption of a Cystic Fibrosis Lung Epithelial Cell Line.". (2015): http://europepmc.org/abstract/med/25486990.
    10.1128/IAI.02713-14
  33. FERNANDES, FABIO. "Electrostatically driven lipid–protein interaction: Answers from FRET". Biochimica et Biophysica Acta (BBA) - Biomembranes 0 (2015): http://www.sciencedirect.com/science/article/pii/S0005273615000632.
    http://dx.doi.org/10.1016/j.bbamem.2015.02.023
  34. Sousa, Tânia; Castro, Rui E.; Pinto, Sandra N.; Coutinho, Ana; Lucas, Susana D.; Moreira, Rui; Rodrigues, Cecília M. P.; Prieto, Manuel; Fernandes, Fábio. "Deoxycholic acid modulates cell death signaling through changes in mitochondrial membrane properties". Journal of Lipid Research (2015):
    10.1194/jlr.M062653
  35. Magalhães S; Duarte S; Monteiro GA; Fernandes F. "Quantitative evaluation of DNA dissociation from liposome carriers and DNA escape from endosomes during lipid-mediated gene delivery.". (2014): http://europepmc.org/abstract/med/25285806.
    10.1089/hgtb.2014.080
  36. Monteiro ME; Sarmento MJ; Fernandes F; Marina E. Monteiro; Maria J. Sarmento; Fábio Fernandes. "Role of calcium in membrane interactions by PI(4,5)P2-binding proteins.". Biochemical Society Transactions 42 5 (2014): 1441-1446. http://europepmc.org/abstract/med/25233429.
    10.1042/BST20140149
  37. Mil-Homens D; Leça MI; Fernandes F; Pinto SN; Fialho AM. "Characterization of BCAM0224, a Multifunctional Trimeric Autotransporter from the Human Pathogen Burkholderia cenocepacia.". (2014): http://europepmc.org/abstract/med/24659767.
    10.1128/JB.00061-14
  38. Fabio Fernandes. "NIR and visible perylenediimide-silica nanoparticles for laser scanning bioimaging". Dyes and Pigments (2014): http://www.sciencedirect.com/science/article/pii/S0143720814001065.
    10.1016/j.dyepig.2014.03.026
  39. Sarmento MJ; Coutinho A; Fedorov A; Prieto M; Fernandes F. "Ca(2+) induces PI(4,5)P2 clusters on lipid bilayers at physiological PI(4,5)P2 and Ca(2+) concentrations.". (2014): http://europepmc.org/abstract/med/24316170.
    10.1016/j.bbamem.2013.11.020
  40. Melo AM; Loura LM; Fernandes F; Villalaín J; Prieto M; Coutinho A. "Electrostatically driven lipid-lysozyme mixed fibers display a multilamellar structure without amyloid features.". (2014): http://europepmc.org/abstract/med/24651998.
    10.1039/c3sm52586d
  41. FERNANDES, FABIO. "Intrinsically Fluorescent Silica Nanocontainers: A Promising Theranostic Platform". Microscopy and Microanalysis (2013): http://dx.doi.org/10.1017/s1431927613001517.
    10.1017/s1431927613001517
  42. FERNANDES, FABIO. "New Visible and NIR Highly Photostable Fluorescent Silica Nanoparticles for Laser Scanning Imaging Applications". Microscopy and Microanalysis (2013): http://dx.doi.org/10.1017/s1431927613001141.
    10.1017/s1431927613001141
  43. Maria João Sarmento; Ana Coutinho; Aleksander Fedorov; Manuel Prieto; Fábio Fernandes. "Physiological Calcium Concentrations Induce PI(4,5)P2 Clustering: PI(4,5)P2 as a Lipidic Calcium Sensor". Biophysical Journal 104 2 (2013): 372a-372a. https://doi.org/10.1016%2Fj.bpj.2012.11.2069.
    10.1016/j.bpj.2012.11.2069
  44. Ferreira, S.A.; Silva, N.I.; Oliveira, H.V.; Becker, D.J.; Givskov, M.; Ryan, P.R.; Fernandes, F.; Moreira, L.M.. "Comparative transcriptomic analysis of the Burkholderia cepacia tyrosine kinase bceF mutant reveals a role in tolerance to stress, biofilm formation, and virulence". Applied and Environmental Microbiology 79 9 (2013): 3009-3020. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876314570&partnerID=MN8TOARS.
    10.1128/AEM.00222-13
  45. Pinto, S.N.; Fernandes, F.; Fedorov, A.; Futerman, A.H.; Silva, L.C.; Prieto, M.. "A combined fluorescence spectroscopy, confocal and 2-photon microscopy approach to re-evaluate the properties of sphingolipid domains". Biochimica et Biophysica Acta - Biomembranes 1828 9 (2013): 2099-2110. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879228705&partnerID=MN8TOARS.
    10.1016/j.bbamem.2013.05.011
  46. Loura, Luis M S; Prieto, Manuel; Fernandes, Fabio. "Forster resonance energy transfer as a tool for quantification of protein-lipid selectivity.". Methods in molecular biology (Clifton, N.J.) 974 (2013): 219-32.
    10.1007/978-1-62703-275-9_10
  47. Ribeiro, Tania; Raja, Sebastian; Rodrigues, Ana Sofia; Fernandes, Fabio; Farinha, Jose Paulo S.; Baleizao, Carlos. "High performance NIR fluorescent silica nanoparticles for bioimaging". Rsc Advances 3 24 (2013): 9171-9174.
    10.1039/c3ra41199k
  48. Mello-Vieira, J.; Sousa, T.; Coutinho, A.; Fedorov, A.; Lucas, S.D.; Moreira, R.; Castro, R.E.; et al. "Cytotoxic bile acids, but not cytoprotective species, inhibit the ordering effect of cholesterol in model membranes at physiologically active concentrations". Biochimica et Biophysica Acta - Biomembranes 1828 9 (2013): 2152-2163. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879241584&partnerID=MN8TOARS.
    10.1016/j.bbamem.2013.05.021
  49. Sarmento, M.J.; Prieto, M.; Fernandes, F.. "Reorganization of lipid domain distribution in giant unilamellar vesicles upon immobilization with different membrane tethers". Biochimica et Biophysica Acta - Biomembranes 1818 11 (2012): 2605-2615. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864051779&partnerID=MN8TOARS.
    10.1016/j.bbamem.2012.05.028
  50. Fernandes, Fabio; Prieto, Manuel; Loura, Luis M. S.. "Advanced FRET methodologies: protein-lipid selectivity detection and quantification". Advances in experimental medicine and biology 749 (2012): 171-85.
  51. Loura, Luis M. S.; Fernandes, Fabio; Prieto, Manuel. "Membrane microheterogeneity: Forster resonance energy transfer characterization of lateral membrane domains". European Biophysics Journal with Biophysics Letters 39 4 (2010): 589-607.
    10.1007/s00249-009-0547-5
  52. Loura, L.M.S.; Fernandes, F.; Fernandes, A.C.; Ramalho, J.P.P.. "Effects of fluorescent probe NBD-PC on the structure, dynamics and phase transition of DPPC. A molecular dynamics and differential scanning calorimetry study". Biochimica et Biophysica Acta - Biomembranes 1778 2 (2008): 491-501. http://www.scopus.com/inward/record.url?eid=2-s2.0-38349004773&partnerID=MN8TOARS.
    10.1016/j.bbamem.2007.10.022
  53. Fernandes, Fabio; Loura, Luis M. S.; Chichon, Francisco J.; Carrascosa, Jose L.; Fedorov, Alexander; Prieto, Manuel. "Role of helix 0 of the N-BAR domain in membrane curvature generation". Biophysical Journal 94 8 (2008): 3065-3073.
    10.1529/biophysj.107.113118
  54. Fernandes, Fabio; Neves, Patricia; Gameiro, Paula; Loura, Luis M. S.; Prieto, Manuel. "Ciprofloxacin interactions with bacterial protein OmpF: Modelling of FRET from a multi-tryptophan protein trimer". Biochimica Et Biophysica Acta-Biomembranes 1768 11 (2007): 2822-2830.
    10.1016/j.bbamem.2007.07.016
  55. Fernandes, F.; Loura, L.; Koehorst, R.B.M.; Dixon, N.; Kee, T.P.; Hemminga, M.A.; Prieto, M.. "Interaction of the indole class of vacuolar H+-ATPase inhibitors with lipid bilayers". Biochemistry 45 16 (2006): 5271-5279. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645965883&partnerID=MN8TOARS.
    10.1021/bi0522753
  56. Fernandes, Fabio; Loura, Luis M. S.; Fedorov, Alexander; Prieto, Manuel. "Absence of clustering of phosphatidylinositol-(4,5)-bisphosphate in fluid phosphatidylcholine". Journal of Lipid Research 47 7 (2006): 1521-1525.
    10.1194/jlr.M600121-JLR200
  57. Fernandes, F.; Loura, L. M. S.; Fedorov, A.; Dixon, N.; Kee, T. P.; Prieto, M.; Hemminga, M. A.. "Binding assays of inhibitors towards selected V-ATPase domains". Biochimica Et Biophysica Acta-Biomembranes 1758 11 (2006): 1777-1786.
    10.1016/j.bbamem.2006.07.006
  58. Fernandes, F; Loura, LMS; Koehorst, R; Spruijt, RB; Hemminga, MA; Fedorov, A; Prieto, M. "Quantification of protein-lipid selectivity using FRET: Application to the M13 major coat protein". Biophysical Journal 87 1 (2004): 344-352.
    10.1529/biophysj.104.040337
  59. Fernandes, F; Loura, LMS; Prieto, M; Koehorst, R. "Dependence of M13 major coat protein oligomerization and lateral segregation on bilayer composition". Biophysical Journal 85 4 (2003): 2430-2441.
    10.1016/S0006-3495(03)74666-9
Capítulo de livro
  1. Sarmento, Maria J.; FERNANDES, FABIO. Autor correspondente: Sarmento, Maria J.. "Choosing the right fluorescent probe". In Springer Series on Fluorescence.. 2023.
    10.1007/4243_2022_30
  2. FERNANDES, FABIO. "Measuring the Impact of Bile Acids on the Membrane Order of Primary Hepatocytes and Isolated Mitochondria by Fluorescence Imaging and Spectroscopy". 2019.
    10.1007/978-1-4939-9420-5_7
  3. FERNANDES, FABIO. "Förster Resonance Energy Transfer as a Tool for Quantification of Protein–Lipid Selectivity". 2019.
    10.1007/978-1-4939-9512-7_16
  4. FERNANDES, FABIO. "Giant hybrid polymer/lipid vesicles". 2019.
    10.1201/9781315152516-27
  5. FERNANDES, FABIO. "Advanced FRET Methodologies: Protein–Lipid Selectivity Detection and Quantification". 2012.
    10.1007/978-1-4614-3381-1_12
Poster em conferência
  1. Sarmento, Maria J.; Pinto, SN; FERNANDES, FABIO; Manuel José Estevez Prieto. "Regulation of PIP2 clustering in neuron-like model cells by synaptic protein palmitoylation". Trabalho apresentado em The 8th EBSA European Biophysics Congress, 2011.
Pré-impressão
  1. Neuza Domingues; Steve Catarino; Beatriz Cristovao; Lisa Rodrigues; Carvalho Filomena; Maria Joao Sarmento; Monica Zuzarte; et al. "Cx43 promotes exocytosis of damaged lysosomes through actin remodelling". 2022. https://doi.org/10.21203/rs.3.rs-2277227/v1.
    10.21203/rs.3.rs-2277227/v1
  2. "Improved Parameterization of Phosphatidylinositide Lipid Headgroups for the Martini 3 Coarse Grain Force Field". 2021. http://dx.doi.org/10.26434/chemrxiv.14759991.v1.
    10.26434/chemrxiv.14759991.v1