Identificação
Identificação pessoal
- Nome completo
- Ivan Salazar
Nomes de citação
- Salazar, IL
Identificadores de autor
- Ciência ID
- 231A-75CA-AD8C
- ORCID iD
- 0000-0001-9667-6766
Endereços de correio eletrónico
- ivan.salazar@uc.pt (Profissional)
Moradas
- Multidisciplinary Institute of Ageing - MIA Portugal, Faculdade de Medicina da Universidade de Coimbra Pólo I, 3º Piso, Rua Larga , 3004-504, Coimbra, Coimbra, Portugal (Profissional)
Websites
- https://www.uc.pt/mia/ageing-research/ira-milosevic-group/ (Profissional)
Domínios de atuação
- Ciências Médicas e da Saúde - Medicina Básica - Neurociências
- Ciências Naturais - Ciências Biológicas - Bioquímica
- Ciências Médicas e da Saúde - Medicina Básica - Neurociências
- Ciências Médicas e da Saúde - Medicina Básica - Neurociências
Idiomas
Idioma | Conversação | Leitura | Escrita | Compreensão | Peer-review |
---|---|---|---|---|---|
Português | Utilizador proficiente (C1) | Utilizador proficiente (C1) | Utilizador proficiente (C1) | Utilizador proficiente (C1) | |
Inglês | Utilizador proficiente (C1) | Utilizador proficiente (C1) | Utilizador proficiente (C1) | Utilizador proficiente (C1) |
Formação
Grau | Classificação | |
---|---|---|
2012/09 - 2017/02
Concluído
|
Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
"Regulation of the Ubiquitin-Proteasome System in brain ischemia: impact on the neuronal proteome" (TESE/DISSERTAÇÃO)
|
Approved with praise and distinction by unanimity |
Percurso profissional
Docência no Ensino Superior
Categoria Profissional Instituição de acolhimento |
Empregador | |
---|---|---|
2021/09 - 2022/02 | Professor Auxiliar Convidado (Docente Universitário) | Universidade de Coimbra Departamento de Ciências da Vida, Portugal |
Outros
Categoria Profissional Instituição de acolhimento |
Empregador | |
---|---|---|
2022/04/01 - Atual | PostDoctoral Fellow | Universidade de Coimbra Multidisciplinary Institute of Ageing, Portugal |
2019/02/01 - 2021/12/31 | Doctorate Investigator (DL57) within the project: Local protein synthesis and alterations in the synaptic proteome in epileptogenesis (POCI-01-0145-FEDER-028656) | Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
2017/06/01 - 2019/01/31 | PostDoctoral Fellowship (CENTRO-01-0145-FEDER-000008: BrainHealth 2020 - Early Detection, Neuromodulation and Advanced Therapies to Brain Disorders) | Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal |
2017/04/01 - 2017/05/31 | PostDoctoral Fellowship (Novel cerebrospinal fluid and serum biomarkers for Multiple Sclerosis patients Multiple Sclerosis_RG-1601-075) | Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
2013/02/01 - 2017/02/07 | Doctoral Programme in Experimental Biology and Biomedicine (Fellowship SFRH/BD/51967/2012), "Regulation of the Ubiquitin-Proteasome System in the ischemic brain: impact on the neuronal proteome | Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal |
2015/05 - 2015/06 | Visiting Fellow at the Laboratory Proteolytic Systems, Institut für Biochemie, Charité – Universitätsmedizin Berlin | Charité Universitätsmedizin Berlin, Alemanha |
2011/06/01 - 2012/07/30 | Graduate student, Master thesis "Dysregulation of the Ubiquitin-Proteasome System in the oxygen and glucose deprivation (OGD) model of transient global ischemia". | Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
2010/07/10 - 2010/08/10 | Short term Summer Fellowship. | Universidade de Coimbra, Portugal |
Projetos
Bolsa
Designação | Financiadores | |
---|---|---|
2019/02/01 - 2021/12 | BDNF-induced alterations in the synaptic proteome and neuronal excitability in the pilocarpine model of temporal lobe epilepsy
PTDC/MED-NEU/28656/2017
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
Associação para a Inovação e Desenvolvimento da FCT
Concluído
|
2016/10 - 2020/10 | Novel cerebrospinal fluid and serum biomarkers for Multiple Sclerosis
Investigador
|
National Multiple Sclerosis Society
Em curso
|
2017/06/01 - 2019/01/31 | Detecção Precoce, Neuro-modulação e Terapias Avançadas para Neuropatologias
Bolseiro de Pós-Doutoramento
|
Em curso
|
2012/09 - 2017/02 | Full PhD Student Fellowship Awarded by the Technology Science Foundation entitled Regulation of the Ubiquitin-Proteasome System
in brain ischemia: impact on the neuronal proteome
(SFRH/BD/ 51967/2012)
Bolseiro de Doutoramento
|
Concluído
|
2012/02/10 - 2015/08 | Regulation of the ubiquitin-proteasome system by BDNF at the hippocampal synapses: role in synaptic plasticity
Investigador
|
Fundação para a Ciência e a Tecnologia
Concluído
|
Produções
Publicações
Artigo em revista |
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Artigo em revista (magazine) |
|
Edição de número de revista |
|
Poster em conferência |
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Pré-impressão |
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Tese / Dissertação |
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Atividades
Apresentação oral de trabalho
Título da apresentação | Nome do evento Anfitrião (Local do evento) |
|
---|---|---|
2021/07 | Salazar, IL., (2021) Novel Multiple Sclerosis Biomarkers. World Brain Day 2021: a callto stop multiple sclerosis (July, 22nd, Colégio da Trindade, Coimbra, Portugal). |
(Portugal)
|
2021/07 | Salazar, IL., Caldeira, MV, Li, KW., & Duarte, CB (2021). Crosstalk between the Ubiquitin-Proteasome System and calpains in neuronal death induced by brain ischemia. Virtual Symposium on Post-translational modifications in neuronal physiology and brain disorders (5-6 July, National Research Council of Italy). | |
2017/02/02 | The interplay between the Ubiquitin-Proteasome System and calpains in brain ischemia: the effect of proteasome inducer in cell demise | Annual meeting of the Portuguese Pharmacological Society
(Coimbra, Portugal)
|
2013/06/23 | Glutamate receptor activation is coupled to 26S proteasome downregulation in in vitro ischemia | 5th Conference on Advances in molecular mechanisms underlying neurological disorders
(Bath, Reino Unido)
|
2013/04/19 | 26S Proteasome downregulation under excitotoxic conditions | 1st Research Coimbra in Health Sciences
(Coimbra, Portugal)
|
Orientação
Título / Tema Papel desempenhado |
Curso (Tipo) Instituição / Organização |
|
---|---|---|
2016/09 - 2017/06 | Crosstalk between the Ubiquitin-Proteasome System and calpains in neuronal death induced by brain ischemia
Orientador
|
|
2013/09 - 2014/06 | Redistribution of the Proteasome in Brain Ischemia
Orientador
|
|
2012/01 - 2012/06 | Biochemistry Intership - Study of the UPS in brain ischemia
Coorientador
|
Organização de evento
Nome do evento Tipo de evento (Tipo de participação) |
Instituição / Organização | |
---|---|---|
2021/05 - 2021/05 | Host of Pedro Beltrão, EMBL-EBI, Cambridgeshire. Proteomics approaches to study SARS-CoV-2 biology and to identify antiviral
drugs. (2021/05 - 2021/05)
Seminário
|
|
2021/03 - 2021/03 | Host of Daniel Finley, Department of Cell Biology, Harvard Medical School. Global remodeling during extreme terminal differentiation.
(2021/03 - 2021/03)
Seminário
|
|
2014/12 - 2014/12 | XII Annual CNC meeting “May the Science be with you" (2014/12/15 - 2014/12/16)
Encontro (Coorganizador)
|
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
2013/06/08 - 2013/06/08 | 2nd BEB Symposium – “Seeding curiosity, harvesting Science" (2013/06/08 - 2013/06/08)
Simpósio (Coorganizador)
|
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
Participação em evento
Descrição da atividade Tipo de evento |
Nome do evento Instituição / Organização |
|
---|---|---|
2023/09 - 2023/09 | International meeting on molecular mechanisms of ageing
Conferência
|
Groningen-Jena Aging meeting (G-AM)
Rijksuniversiteit Groningen, Países Baixos
|
2022/09 - 2022/09 | International meeting on Synaptic Plasticity
Conferência
|
BrainConf: Synaptic Plasticity
Université de Bordeaux, França
|
2019/11/15 - 2019/11/19 | Workshop on mechanisms of protein quality control
Congresso
|
EMBO Workshop on Proteostasis: from organelles to organisms |
2019/05/30 - 2019/06/01 | Portuguese Neuroscience Meeting
Congresso
|
XVI Meeting of the Portuguese Society for Neuroscience |
2017/08/20 - 2017/08/24 | International Neuroscience Meeting
Congresso
|
ISN-ESN biennial meeting |
2016/06/01 - 2016/06/04 | International Neuroscience Meeting
Congresso
|
7th ISN Special Neurochemistry Conference- Synaptic Function and Dysfunction In Brain Diseases |
2014/07/04 - 2014/07/09 | International Neuroscience Meeting
Congresso
|
9th FENS Forum of Neuroscience |
2013/06/20 - 2013/06/23 | International Meeting on Neuronal Proteolysis
Congresso
|
5th Conference on Advances in molecular mechanisms underlying neurological disorders |
Júri de grau académico
Tema Tipo de participação |
Nome do candidato (Tipo de grau) Instituição / Organização |
|
---|---|---|
2023/09 | ROS and zinc changes evoked by Hypoxia in Hippocampus'
Arguente principal
|
João Lourenço Ribeiro Alves (Mestrado)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
|
2020/09 | Unveiling the protective role of Transthyretin in mice stroke model: using a behavioral screening workflow
Arguente principal
|
Raquel Sofia Pinto (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
|
2019/09/15 | Unraveling the pathophysiological mechanisms behind white matter lesions: a study on cerebrospinal fluid and blood markers
in patients with cerebral small vessel disease
Arguente principal
|
Anuschka da Silva Spínola (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
|
Arbitragem científica em revista
Nome da revista (ISSN) | Editora | |
---|---|---|
2023/09 - Atual | Autophagy (co-reviewer) | |
2020 - Atual | Biomolecules (2218-273X) | MDPI AG |
2020 - Atual | International Journal of Molecular Sciences (1422-0067) | MDPI AG |
2020 - Atual | Cancers (2072-6694) | MDPI AG |
2020 - Atual | Cells (Reviewer Member Board) (2073-4409) | MDPI AG |
2020 - Atual | International Research Journal of Public and Environmental Health (2360-8803) | Journal Issues Limited |
2019 - Atual | Heliyon (Reviewer) (2405-8440) | Elsevier |
2019 - Atual | Neurochemical Research (Reviewer) (1573-6903) | Springer-Verlag |
2019 - Atual | Journal of Visualized Experiments (Co-Reviewer) (1940-087X) | MyJoVE Corporation |
2017 - Atual | Frontiers in Aging Neuroscience (Co-Reviewer) (1663-4365) | Frontiers Media SA |
2017 - Atual | Frontiers in Synaptic Neuroscience (Co-Reviewer) (1663-3563) | Frontiers Media SA |
2017 - Atual | Scientific Reports (Co-Reviewer) (2045-2322) | Springer Science and Business Media LLC |
2015 - Atual | Brain Research (Co-Reviewer) (0006-8993) | Elsevier |
2015 - Atual | FEBS Letters (Co-Reviewer) (1873-3468) | Wiley (John Wiley & Sons) |
2015 - Atual | Cellular and Molecular Neurobiology (Co-Reviewer) (1573-6830) | Springer-Verlag |
2015 - Atual | Journal of Molecular Histology (Co-Reviewer) (1567-2387) | Springer-Verlag |
2014 - Atual | Molecular Neurobiology (Co-Reviewer) (0893-7648) | Springer-Verlag |
2013 - Atual | PLoS ONE (Co-Reviewer) (1932-6203) | Public Library of Science |
2012 - Atual | Neuroscience Letters (Co-Reviewer) (0304-3940) | Elsevier |
2012 - Atual | Neurochemical Research (Co-Reviewer) (1573-6903) | Springer-Verlag |
Curso / Disciplina lecionado
Disciplina | Curso (Tipo) | Instituição / Organização | |
---|---|---|---|
2012/09 - Atual | Cell Regulation (02001323; Master Program in Cellular and Molecular Biology), laboratory classes for evaluating proteasome activity; aprox 5 hours/year | (Mestrado) | Universidade de Coimbra Departamento de Ciências da Vida, Portugal |
2021/09 - 2022/02 | Cell Regulation (02001323; Master Program in Cellular and Molecular Biology, FCTUC University of Coimbra), theoretical classes; 7 hours (Cytoskeleton and cell movement: 4.5 hours, Cell Adhesion 1.5 hours, Regulation of gene expression 1 hour) laboratory classes; 44 hours - co-organizer | (Mestrado) | Universidade de Coimbra Departamento de Ciências da Vida, Portugal |
2021/09 - 2022/02 | Cellular and Molecular Neurobiology (02001298; Master Program in Cellular and Molecular Biology, FCTUC University of Coimbra), TP classes; 16 hours (Journal Club) | (Mestrado) | Universidade de Coimbra Departamento de Ciências da Vida, Portugal |
2021/09 - 2022/02 | Cellular and Molecular Biology (01000861; Bachelor in Biomedical Engineering/Medicinal Chemistry/Biochemistry, FCTUC University of Coimbra), laboratory classes; 42 hours. | (Licenciatura) | Universidade de Coimbra Departamento de Ciências da Vida, Portugal |
2022/01 - 2022/01 | Neuroscience (48084; Master Program in Molecular Biomedicine), Ischemia and Reperfusion classes; 2 hours - invited speaker by Ramiro D. Almeida | (Mestrado) | Universidade de Aveiro Departamento de Ciências Médicas, Portugal |
2022 - 2022 | Movement and Demyelinating Disorders (02038170, Master in Molecular and Translational Neuroscience, FMUC University of Coimbra), 1 hour Meet the Investigators Series - invited speaker by Sónia Baptista | ||
2021/01 - 2021/01 | Neuroscience (48084; Master Program in Molecular Biomedicine), Ischemia and Reperfusion classes; 3 hours - invited speaker by Ramiro D. Almeida | (Mestrado) | Universidade de Aveiro Departamento de Ciências Médicas, Portugal |
2020/12 - 2020/12 | Neurobiology (14241065; Bachelor in Biomedical Sciences, University of Algarve), Proteostasis in stroke injury Teaching Seminar; 2 hours. | (Bacharelato) | Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal |
2019/10 - 2019/10 | Neuroscience (48084; Master Program in Molecular Biomedicine), Ischemia and Reperfusion classes; 3 hours - invited speaker by Ramiro D. Almeida | (Mestrado) | Universidade de Aveiro Departamento de Ciências Médicas, Portugal |
2019/03 - 2019/03 | Neurobiology and Disease (02001301; Master Program in Cellular and Molecular Biology), Ischemia and Reperfusion classes; 4 hours - invited speaker by Carlos B. Duarte | (Mestrado) | Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal |
Entrevista / Programa (rádio / tv)
Programa | Tema | |
---|---|---|
2022/04/20 - 2022/04/20 | Programa Consultório (National TV Channel Porto Canal) | Program adressing the work on Multiple Sclerosis Biomarkers |
2022/04/20 - 2022/04/20 | SIC News (National TV Channel SIC) | Interview for SIC News on Multiple Sclerosis Biomarkers |
2022 - 2022 | 90 seconds with Science (Antena1 radio station ep1566) | Program on Science and Research with the most varied topics of the present time |
Membro de associação
Nome da associação | Tipo de participação | |
---|---|---|
2016 - Atual | International Society for Neuroschemistry | Member |
2014/01/09 - Atual | Biochemical Society | Member |
Outro júri / avaliação
Descrição da atividade | Instituição / Organização | |
---|---|---|
2023/05/15 - 2023/05/15 | PhD's project committee of Emanuel Tahiri, 'Autophagy dysfunction in axons: new evidence for Alzheimers disease pathogenesis', PhD Programme in Experimental Biology and Biomedicine. | Universidade de Coimbra, Portugal |
Tutoria
Tópico | Nome do aluno | |
---|---|---|
2012 - Atual | Outreaching Activities: Ciência Viva programme, Science&Holliday high-school students, Instituto de Educação e Cidadania IEC holliday students. | n.a |
Distinções
Prémio
2019 | Travel grant for the EMBO Workshop Proteostasis: from organelles to organisms, Ericeira, Portugal (15-19 November, 2019) -
amount received £450.
Biochemical Society, Reino Unido
|
2017 | Travel grant for the ISN-ENS Biennial meeting, Paris, France (20-24 August, 2017) - amount received £300.
Biochemical Society, Reino Unido
|
2017 | Travel grant and waived registration for the ISN-ENS Biennial meeting, Paris, France (20-24 August, 2017) - amount received
800 USD.
International Society for Neurochemistry, Suiça
|
2016 | Waived registration for the 7th ISN Special Neurochemistry Conference- Synaptic Function and Dysfunction In Brain Diseases
(1-4 June, Coimbra, Portugal).
International Society for Neurochemistry, Suiça
|
2013 | Travel grant for the “5th Conference on Advances in molecular mechanisms underlying neurological disorders”, Bath, UK
Biochemical Society, Reino Unido
|
2008 | Best 3% alumni in the Biology Bachelor given by the Faculty of Science and Technology
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
|
Outra distinção
2017 | PostDoctoral Fellowship by CNC (Multiple Sclerosis_RG-1601-075 project) |
2017 | PostDoctoral Fellowship by UC (CENTRO-01-0145-FEDER-000008: BrainHealth 2020 - Early Detection, Neuromodulation and Advanced
Therapies to Brain Disorders)
Universidade de Coimbra, Portugal
|
2012 | Full PhD Fellowship in the Experimental Biology and Biomedicine PhD Programme (FCT fellowship SFRH/BD/51967/2012) |