Sofia Cravino Serra (271F-C670-96B5)

Curriculum Vitae

Sofia Cravino Serra

Identificação

Identificação pessoal

Nome completo: Sofia Cravino Serra

Identificadores de autor

Ciência ID: 271F-C670-96B5

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2011/12/04 - Atual	Investigador (Investigação)	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Projetos

Bolsa

	Designação	Financiadores
2018/08/10 - 2021/08/09	Development of an autologous exosome-based therapy by engineering microRNAs in microglia and motor-neurons using mice and human models of amyotrophic lateral sclerosis (ALS) PTDC/MED-NEU/31395/2017 Investigador Universidade do Minho, Portugal Universidade de Lisboa Faculdade de Farmácia, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2018/07/26 - 2021/07/25	Restoring the Functionality to the Injured Spinal Cord Through the Combinatory Action of Pharmaco-Therapies and Tissue Engineering Strategies PTDC/CAL-EST/29206/2017 Investigador Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2018/07/01 - 2021/06/30	Combining Mesenchymal Stem Cells (MSCs) Secretome and Pharmacotherapies for the treatment of Parkinson?s Disease PTDC/MED-FAR/29751/2017 Investigador Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2018/07/01 - 2021/06/30	Intracellular Quantum Sensing Techniques for Personalized Medicines of Neurodegenerative Diseases PTDC/NAN-OPT/32619/2017 Investigador International Iberian Nanotechnology Laboratory, Portugal Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2016/06/01 - 2020/05/15	Targeting Spinal Cord Injury Repair Through Nanoporous Biodegradable 3D Matrices TUBITAK/0007/2014 Bolseiro de Investigação Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2013/05/01 - 2015/09/30	DJ-1 neuronal rescue under oxidative stress: implications for Parkinson's disease PTDC/NEU-NMC/0205/2012 Investigador Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universidade do Minho, Portugal Universidade da Beira Interior, Portugal	Fundação para a Ciência e a Tecnologia Concluído

Produções

Publicações

Artigo em revista

Campos J; Sampaio-Marques B; Santos D; Barata-Antunes S; Ribeiro M; Serra SC; Pinho TS; et al. "Lipid Priming of Adipose Mesenchymal Stromal Cells with Docosahexaenoic Acid: Impact on Cell Differentiation, Senescence and the Secretome Neuroregulatory Profile.". Tissue engineering and regenerative medicine (2024): http://europepmc.org/abstract/med/39495459.
10.1007/s13770-024-00679-5
Lentilhas-Graça J; Santos DJ; Afonso J; Monteiro A; Pinho AG; Mendes VM; Dias MS; et al. "The secretome of macrophages has a differential impact on spinal cord injury recovery according to the polarization protocol.". Frontiers in immunology (2024): http://europepmc.org/abstract/med/38444856.
10.3389/fimmu.2024.1354479
Mendes-Pinheiro B; Campos J; Marote A; Soares-Cunha C; Nickels SL; Monzel AS; Cibrão JR; et al. "Treating Parkinson's Disease with Human Bone Marrow Mesenchymal Stem Cell Secretome: A Translational Investigation Using Human Brain Organoids and Different Routes of In Vivo Administration.". Cells (2023): http://europepmc.org/abstract/med/37947643.
10.3390/cells12212565
Pinho AG; Cibrão JR; Lima R; Gomes ED; Serra SC; Lentilhas-Graça J; Ribeiro C; et al. "Immunomodulatory and regenerative effects of the full and fractioned adipose tissue derived stem cells secretome in spinal cord injury.". Experimental neurology (2022): http://europepmc.org/abstract/med/35065953.
10.1016/j.expneurol.2022.113989
Correia JS; Neves-Carvalho A; Mendes-Pinheiro B; Pires J; Teixeira FG; Lima R; Monteiro S; et al. "Preclinical Assessment of Mesenchymal-Stem-Cell-Based Therapies in Spinocerebellar Ataxia Type 3.". Biomedicines (2021): http://europepmc.org/abstract/med/34944570.
10.3390/biomedicines9121754
Campos J; Guerra-Gomes S; Serra SC; Baltazar G; Oliveira JF; Teixeira FG; Salgado AJ. "Astrocyte signaling impacts the effects of human bone marrow mesenchymal stem cells secretome application into the hippocampus: A proliferation and morphometrical analysis on astrocytic cell populations.". Brain research (2020): http://europepmc.org/abstract/med/32032613.
10.1016/j.brainres.2020.146700
Serra SC; Costa JC; Assunção-Silva RC; Teixeira FG; Silva NA; Anjo SI; Manadas B; et al. "Influence of passage number on the impact of the secretome of adipose tissue stem cells on neural survival, neurodifferentiation and axonal growth.". Biochimie (2018): http://europepmc.org/abstract/med/30342112.
10.1016/j.biochi.2018.09.012
Oliveira AI; Anjo SI; Vieira de Castro J; Serra SC; Salgado AJ; Manadas B; Costa BM. "Crosstalk between glial and glioblastoma cells triggers the "go-or-grow" phenotype of tumor cells.". Cell communication and signaling : CCS (2017): http://europepmc.org/abstract/med/28969644.
10.1186/s12964-017-0194-x
Serra, Sofia Cravino. "Mesenchymal stem cells secretome-induced axonal outgrowth is mediated by BDNF.". Scientific reports (2017): http://europepmc.org/abstract/med/28646200.
10.1038/s41598-017-03592-1
Pires AO; Teixeira FG; Mendes-Pinheiro B; Serra SC; Sousa N; Salgado AJ. "Old and new challenges in Parkinson's disease therapeutics.". (2017): http://europepmc.org/abstract/med/28457671.
10.1016/j.pneurobio.2017.04.006
Pires AO; Mendes-Pinheiro B; Teixeira FG; Anjo SI; Ribeiro-Samy S; Gomes ED; Serra SC; et al. "Unveiling the Differences of Secretome of Human Bone Marrow Mesenchymal Stem Cells, Adipose Tissue-Derived Stem Cells, and Human Umbilical Cord Perivascular Cells: A Proteomic Analysis.". (2016): http://europepmc.org/abstract/med/27226274.
10.1089/scd.2016.0048
Teixeira FG; Panchalingam KM; Assunção-Silva R; Serra SC; Mendes-Pinheiro B; Patrício P; Jung S; et al. "Modulation of the Mesenchymal Stem Cell Secretome Using Computer-Controlled Bioreactors: Impact on Neuronal Cell Proliferation, Survival and Differentiation.". (2016): http://europepmc.org/abstract/med/27301770.
10.1038/srep27791
Abreu AC; Serra SC; Borges A; Saavedra MJ; Mcbain AJ; Salgado AJ; Simões M. "Combinatorial Activity of Flavonoids with Antibiotics Against Drug-Resistant Staphylococcus aureus.". (2015): http://europepmc.org/abstract/med/25734256.
10.1089/mdr.2014.0252
Sevivas N; Serra SC; Portugal R; Teixeira FG; Carvalho MM; Silva N; Espregueira-Mendes J; Sousa N; Salgado AJ. "Animal model for chronic massive rotator cuff tear: behavioural and histologic analysis.". (2015): http://europepmc.org/abstract/med/25416674.
10.1007/s00167-014-3441-3
Neves-Carvalho A; Logarinho E; Freitas A; Duarte-Silva S; Costa Mdo C; Silva-Fernandes A; Martins M; et al. "Dominant negative effect of polyglutamine expansion perturbs normal function of ataxin-3 in neuronal cells.". (2015): http://europepmc.org/abstract/med/25143392.
10.1093/hmg/ddu422
Lamas NJ; Serra SC; Salgado AJ; Sousa N. "Failure of Y-27632 to improve the culture of adult human adipose-derived stem cells.". (2015): http://europepmc.org/abstract/med/25609984.
10.2147/SCCAA.S66597
Wrobel S; Serra SC; Ribeiro-Samy S; Sousa N; Heimann C; Barwig C; Grothe C; Salgado AJ; Haastert-Talini K. "In vitro evaluation of cell-seeded chitosan films for peripheral nerve tissue engineering.". (2014): http://europepmc.org/abstract/med/24606318.
10.1089/ten.TEA.2013.0621
Abreu AC; Serra SC; Borges A; Saavedra MJ; Salgado AJ; Simões M. "Evaluation of the best method to assess antibiotic potentiation by phytochemicals against Staphylococcus aureus.". (2014): http://europepmc.org/abstract/med/24717959.
10.1016/j.diagmicrobio.2014.03.002
Borges A; Serra S; Cristina Abreu A; Saavedra MJ; Salgado A; Simões M. "Evaluation of the effects of selected phytochemicals on quorum sensing inhibition and in vitro cytotoxicity.". (2014): http://europepmc.org/abstract/med/24344870.
10.1080/08927014.2013.852542

Capítulo de livro

Teixeira, F.G.; Pires, A.; Serra, S.C.; Sousa, N.; Salgado, A.J.. "The evolving concept of mesenchymal stromal cells in regenerative medicine". In The Biology and Therapeutic Application of Mesenchymal Cells, 222-235. John Wiley & Sons, Inc., 2017.
Publicado • 10.1002/9781118907474.ch18
Teixeira FG; Serra SC; Salgado AJ. "Tips on How to Collect and Administer the Mesenchymal Stem Cell Secretome for Central Nervous System Applications.". 2016.
10.1007/978-1-4939-3584-0_27