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Ana Cristina Pontes de Carvalho is a postdoctoral researcher at the 3B´s Research Group and her academic background includes: BSc in Applied Biology (2008), MSc in Molecular Genetics (2012), and PhD in Molecular and Environmental Biology (2017). During her scientific journey, she participated in several projects that allowed her to acquire extensive experience in cell and molecular biology mainly in the study of biologically active compounds and extracts. Her first contact with this research area was in 2010 when she integrated the NaturAge project to evaluate the anti-aging properties of natural compounds. As a PhD student and a postdoctoral researcher of the Interact project, she continued to work in the evaluation of biological activities of natural/chemical compounds and extracts. The work carried out has resulted in 6 articles in international journals, 1 book chapter and several communications in scientific meetings. Currently, she is dedicated to evaluate the biological activities of marine algae and cyanobacteria extracts, under the scope of the project ValorMar - Full valorization of marine resources: potential, technological innovation and new applications.
Identificação

Identificação pessoal

Nome completo
Ana Cristina Pontes de Carvalho

Nomes de citação

  • Carvalho, Ana C.

Identificadores de autor

Ciência ID
4A14-BD84-D5BF
ORCID iD
0000-0002-1102-5372
Researcher Id
J-7422-2013

Endereços de correio eletrónico

  • cristina.carvalho@i3bs.uminho.pt (Profissional)
  • anacpcarvalho@gmail.com (Pessoal)

Moradas

  • 3B's Research Group, Avepark - Parque de Ciência e Tecnologia, Zona Industrial da Gandra , 4805-017, Barco, Guimarães, Portugal (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Ciências da Saúde
  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Francês Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1)
Galego Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Polaco Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2013 - 2017
Concluído
Molecular and Environmental Biology (Doutoramento)
Especialização em Cellular Biology and Health
Universidade do Minho, Portugal
"Hormetic induction of antioxidant defenses for promotion of healthy aging." (TESE/DISSERTAÇÃO)
Very Good
2008 - 2012
Concluído
Molecular Genetics (Mestrado)
Universidade do Minho, Portugal
"Temporal characterization of molecular clock genes and its importance in the embryonic stem cells differentiation potential." (TESE/DISSERTAÇÃO)
18
2005 - 2008
Concluído
Applied Biology (Licenciatura)
Universidade do Minho, Portugal
15
Percurso profissional

Ciência

2019/05/15 - Atual Pós-doutorado (Investigação)
Universidade do Minho, Portugal
2018/06/25 - 2019/04/30 Pós-doutorado (Investigação)
Universidade de Trás-os-Montes e Alto Douro, Portugal
Projetos

Bolsa

Designação Financiadores
2019 - Atual ValorMar - Full valorization of marine resources: potential, technological innovation and new applications
POCI-01-0247-FEDER-024517
Bolseiro de Pós-Doutoramento
Universidade do Minho, Portugal
2018 - 2019/04/30 Interact – Integrative Research in Environment, Agro-Chain and Technology
NORTE-01-0145-FEDER-000017
Bolseiro de Pós-Doutoramento
Universidade de Trás-os-Montes e Alto Douro, Portugal
2013 - 2017/04 Hormetic induction of antioxidant defenses for promotion of healthy aging
SFRH/BD/86953/2012
Bolseiro de Doutoramento
Fundação para a Ciência e a Tecnologia
2010 - 2013/04/30 NaturAge - Anti-aging properties of natural compounds
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/101392/PT
Bolseiro de Investigação
Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Produções

Publicações

Artigo em revista
  1. Jesus, Meirielly S.; Ballesteros, Lina F.; Pereira, Ricardo N.; Genisheva, Zlatina; Carvalho, Ana S.; Pereira-Wilson, Cristina; Teixeira, José A; Domingues, Lucília. "Ohmic heating polyphenolic extracts from vine pruning residue with enhanced biological activity". Food Chemistry (2020): 126298. http://dx.doi.org/10.1016/j.foodchem.2020.126298.
    10.1016/j.foodchem.2020.126298
  2. Martins, M.; Azoia, N. G.; Carvalho, A. C.; Silva, C.; Matamá, T.; Gomes, A. C.; Cavaco-Paulo, A.. "Assessment of a Protease Inhibitor Peptide for Anti-Ageing". Protein Pept Lett 22 11 (2015): 1041-9. https://www.ncbi.nlm.nih.gov/pubmed/26343064.
  3. Carvalho, Ana C.; Gomes, Andreia C.; Pereira-Wilson, Cristina; Lima, Cristovao F.. "Redox-dependent induction of antioxidant defenses by phenolic diterpenes confers stress tolerance in normal human skin fibroblasts: Insights on replicative senescence". Free Radical Biology and Medicine 83 (2015): 262-272. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000355577600026&KeyUID=WOS:000355577600026.
    10.1016/j.freeradbiomed.2015.02.022
  4. Carvalho, Ana C.; Franklin, Gregory; Dias, Alberto C. P.; Lima, Cristovao F.. "Methanolic extract of Hypericum perforatum cells elicited with Agrobacterium tumefaciens provides protection against oxidative stress induced in human HepG2 cells". Industrial Crops and Products 59 (2014): 177-183. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000339600400026&KeyUID=WOS:000339600400026.
    10.1016/j.indcrop.2014.05.018
  5. Silva, Raquel; Ferreira, Helena; Carvalho, Ana C.; Gomes, Andreia C.; Cavaco-Paulo, Artur. "Protein microspheres as suitable devices for piroxicam release". Colloids and Surfaces B-Biointerfaces 92 (2012): 277-285. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000300859000039&KeyUID=WOS:000300859000039.
    10.1016/j.colsurfb.2011.11.050
  6. Vasconcelos, Andreia; Azoia, Nuno G.; Carvalho, Ana C.; Gomes, Andreia C.; Gueebitz, Georg; Cavaco-Paulo, Artur. "Tailoring elastase inhibition with synthetic peptides". European Journal of Pharmacology 666 1-3 (2011): 53-60. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000293050900008&KeyUID=WOS:000293050900008.
    10.1016/j.ejphar.2011.05.056
Capítulo de livro
  1. Carvalho, Ana C.. "Chapter 35 - Mechanisms of Action of Curcumin on Aging: Nutritional and Pharmacological Applications". editado por Marco Malavolta; Eugenio Mocchegiani, 491-511. Academic Press, 2016.
    https://doi.org/10.1016/B978-0-12-801816-3.00035-2
Poster em conferência
  1. Carvalho, A.C. (4A14-BD84-D5BF); Reis, R.L.; Silva, T.H.. "Marine algae and cyanobacteria as sources of natural products with anticancer and immunomodulatory properties". Trabalho apresentado em TERMSTEM 2019, 2019.
  2. Carvalho, A.C. (4A14-BD84-D5BF); Reis, R.L.; Silva, T.H.. "Evaluation of biological activities of marine algae and cyanobacteria extracts". Trabalho apresentado em 1st Discoveries Forum on Regenerative and Precision Medicine, 2019.
  3. Carvalho, A.C. (4A14-BD84-D5BF); Costa, M.; Proença, F.; Pereira-Wilson, C.; Gomes, A.C.; Lima, C.F.. "Novel chromene derivatives induce antioxidant defenses and provide protection against oxidative stress induced in HepG2 cells.". Trabalho apresentado em XIX Nacional Congress of Biochemistry., 2016.
  4. Pinho, C.; Oliveira, A.; Paraíso, N.; Carvalho, A.C. (4A14-BD84-D5BF); Lima, C.F.; Dias, A.C.P.. "Evaluation of antioxidant activity of selected Brazilian plants extracts.". Trabalho apresentado em 62nd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), 2014.
  5. Pinho, C.; Oliveira, A.; Carvalho, A.C. (4A14-BD84-D5BF); Lima, C.F.; Dias, A.C.P.. "In vitro anti-cancer activities of Poiretia bahiana and Acritopappus confertus.". Trabalho apresentado em 62nd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA)., 2014.
  6. Borges, C.; Ribeiro, A.J.; Carvalho, A.C. (4A14-BD84-D5BF); Sousa, F.; Oliveira, I.; Batista, I.; Bandarra, N.M.; Gomes, A.C.; Cavaco-Paulo, A.. "Study of sardine oil antioxidant properties for the development of topical therapeutic formulations.". Trabalho apresentado em 62nd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA)., 2014.
  7. Carvalho, A.C. (4A14-BD84-D5BF); Franklin, G.; Dias, A.C.P.; Lima, C.F.. "Protection of human HepG2 cells against oxidative stress by a methanolic extract of Hypericum perforatum elicited with Agrobacterium tumefaciens.". Trabalho apresentado em 62nd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA)., 2014.
    10.24264/icams-2018.i.12
  8. Carvalho, A.C. (4A14-BD84-D5BF); Gomes, A.C.; Pereira-Wilson, C.; Lima, C.F.. "Hormetic induction of antioxidant defenses by phenolic diterpenes posses anti-aging effects in normal human skin fibroblasts.". Trabalho apresentado em 8th International Conference on Polyphenols Applications - ISANH Polyphenols 2014., 2014.
  9. Carvalho, A.C. (4A14-BD84-D5BF); Franklin, G.; Dias, A.C.P.; Lima, C.F.. "Elicitation of Hypericum perforatum cells with Agrobacterium tumefaciens induces production of bioactive phytochemicals that afford protection against oxidative stress induced in human HepG2 cells.". Trabalho apresentado em International Symposium on “Redox Signaling and Oxidative Stress in Health and Disease”, 2012.
  10. Carvalho, A.C. (4A14-BD84-D5BF); Gomes, A.C.; Pereira-Wilson, C.; Lima, C.F.. "Induction of antioxidant defenses by diterpenic phenolics in human fibroblasts: relevance for ageing interventions.". Trabalho apresentado em International Symposium on “Redox Signaling and Oxidative Stress in Health and Disease”, 2012.
  11. Lima, C.F.; Carvalho, A.C. (4A14-BD84-D5BF); Franklin, G.; Dias, A.C.P.. "Induction of antioxidant defenses in human HepG2 cells by a methanolic extract of Hypericum perforatum cells elicited with Agrobacterium tumefaciens.". Trabalho apresentado em Microbiotec’11, 2011.
  12. Carvalho, A.C. (4A14-BD84-D5BF); Gomes, A.C.; Pereira-Wilson, C.; Lima, C.F.. "Induction of antioxidant defenses by diterpenic phenolics in human fibroblasts for nutritional applications toward anti-aging interventions.". Trabalho apresentado em Microbiotec’11., 2011.
  13. Lima, C.F.; Carvalho, A.C. (4A14-BD84-D5BF); Gomes, A.C.; Pereira-Wilson, C.; Rattan, S.I.S.. "Induction of cellular stress responses by phytochemicals for nutritional applications toward anti-aging interventions.". Trabalho apresentado em XVII Nacional Congress of Biochemistry., 2010.
  14. Soares-Castro, P.; Lima, C.F.; Silva, J.P.N.; Carvalho, A.C. (4A14-BD84-D5BF); Gomes, A.C.. "Regulation of cellular antioxidant response during myogenesis.". Trabalho apresentado em XVII Nacional Congress of Biochemistry., 2010.
  15. Soares-Castro, P.; Lima, C.F.; Silva, J.P.N.; Carvalho, A.C. (4A14-BD84-D5BF); Gomes, A.C.. "Dynamic role of reactive oxygen species and cellular antioxidant response during myogenic differentiation.". Trabalho apresentado em XXXV Jornadas Portuguesas de Genética, 2010.
Tese / Dissertação
  1. Carvalho, Ana C.. "Hormetic induction of antioxidant defenses for promotion of healthy aging". Doutoramento, 2017.
  2. Carvalho, Ana C.. "Temporal characterization of molecular clock genes and its importance in the embryonic stem cells differentiation potential". Mestrado, 2012.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2016/09/23 Hormetic induction of antioxidant defences by phenolic diterpenes for promotion of a healthy ageing 10th European Congress of Biogerontology and 6th Biogerontogical Meeting.
(Warsaw, Polónia)

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2018/12/05 The use of the comet assay to characterize the effects of dietary constituents on the prevention and treatment of colon cancer
Vogal
Diogo Miguel Reis do Vale (Mestrado)
Universidade do Minho Departamento de Biologia, Portugal
Distinções

Prémio

2016 SPB scholarship to attend the XX National Congress of Biochemistry