Duarte Nuno Almeida Carvalho (5413-D169-B418)

Curriculum Vitae

Duarte Nuno Almeida Carvalho

Duarte Nuno Carvalho was born in 1992 in Lousada, Porto, Portugal. Nowadays, he works since 1st of April 2023 as an senior research technician at the Molecular and Analytical Medicine Lab (I3s, and Faculty of Medicine, U.Porto) where his work is focused on applying his skillset in biotechnology and materials towards the development of new molecular-based biosensing technologies for neurodegenerative diseases, hired by the project LIFESAVER (H2020-LC-GD-2020-3-101036702-LIFESAVER). As a result, he contributed until now with 1 scientific article as shared first authorship, 1 as co-author, and 1 poster communication. As background, he graduated in Marine Biology and Biotechnology at Instituto Politécnico de Leiria, Escola Superior de Turismo e Tecnologia do Mar de Peniche, campus 4, Portugal, in 2015. After that, during his master's degree in Marine resources biotechnology, he had the opportunity to be involved in research activities in 3B's Research Group, I3Bs ¿ Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, which his work resulted in his master's thesis, entitled "Marine collagen-chitosan-fucoidan cryogels as cell-laden biocomposites envisaging cartilage tissue engineering" finished in 2017, and realized three scientific publications (1 as the first author), 1 patent and 2 scientific posters, also within the marine biomaterials field. In 2018, he joined 3B's Research Group after being awarded a grant under Project 0245_IBEROS_1_E, financial support of FEDER in the scope of the INTERREG V-A Espanha-Portugal (POCTEP) 2014-2020 program where he had the opportunity to continue the work on the exploration and valorization of marine resources and their by-products, in a sustainable form, for the development of innovative biomaterials for biomedical applications under cartilage tissue engineering approach, linked to the areas of green and blue technology. In September of 2018, he started the Ph.D. degree in Tissue Engineering, Regenerative Medicine & Stem Cells (TERM&SC), funded by "Fundação para a Ciência e Tecnologia" (FCT, Portugal), ref. PD/BD/143044/2018 and COVID/BD/153028/2022 (exceptional scholoarship for COVID mitigation - 5 months financial), under the supervision of Doctor Tiago H. Silva from 3B's Research Group (Portugal) and Doctor Michael Gelinsky from Technical University of Dresden (Germany) which he spends 4 months in Dresden for apply him marine research to 3D bioprinting approach, resulting in 1 scientific article and 1 poster as first author. As a result of his entire Ph.D. work, he has contributed to 6 scientific publications as first author, 2 reviews also as first author and another 2 as co-author, 1 book chapter, and participated in international conferences, which resulted in 2 oral communications and 17 poster communications, 9 of them as first author. In summary, he has authored 7 peer-reviewed articles as the first author (accepted in Q1 journals), collaborated on 2 more as a co-author, and shares first authorship on 1 (currently submitted) publication. Additionally, he holds 1 patent, contributed a peer-reviewed book chapter, authored 2 reviews as the lead author, co-authored 2 more (with 1 under revision), delivered 2 oral presentations, and presented 18 posters at international conferences. Furthermore, he have been worked as a designer of scientific illustrations for several publications, project calls, and conferences.

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Identificação

Identificação pessoal

Nome completo: Duarte Nuno Almeida Carvalho
Género: Masculino

Nomes de citação

Carvalho, Duarte Nuno
Duarte Nuno Carvalho

Identificadores de autor

Ciência ID: 5413-D169-B418
ORCID iD: 0000-0003-3115-0012
Researcher Id: L-1479-2018

Endereços de correio eletrónico

duartec@i3s.up.pt (Profissional)
du-artnunocarvalho@outlook.pt (Pessoal)

Telefones

Telemóvel

(+351) 916066939 (Pessoal)

Moradas

i3S - Instituto de Investigação e Inovação em Saúde, Rua Alfredo Allen 208, 4200-135, Porto, Porto, Portugal (Profissional)

Domínios de atuação

Ciências Naturais - Ciências Biológicas - Biologia Marinha
Ciências da Engenharia e Tecnologias - Biotecnologia Industrial - Bioprodutos Biomateriais
Ciências Exatas - Química - Ciência de Polímeros
Ciências Exatas - Química - Química Analítica
Ciências Naturais - Ciências Biológicas - Microbiologia
Ciências da Engenharia e Tecnologias - Engenharia dos Materiais - Engenharia dos Materiais

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão	Peer-review
Português (Idioma materno)
Inglês	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador proficiente (C1)
Espanhol; Castelhano	Utilizador elementar (A2)	Utilizador elementar (A2)	Utilizador elementar (A2)	Utilizador independente (B1)	Utilizador elementar (A2)

Formação

	Grau	Classificação
2023/10/03 Concluído	Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais (Doutoramento) Especialização em Sem especialidade Universidade do Minho, Portugal "Tissue Engineering Strategies Based on Marine Biomaterials for Regenerationof Cartilage Tissue." (TESE/DISSERTAÇÃO)	Very good (max grade)
2015/09/01 - 2017/10/26 Concluído	Biotecnologia dos Recursos Marinhos (Mestrado) Especialização em Sem especialização Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal "Marine collagen-chitosan-fucoidan cryogels as cell-laden biocomposites envisaging cartilage tissue engineering" (TESE/DISSERTAÇÃO)	17 out of 20
2015/07/24 Concluído	Biologia Marinha e Biotecnologia (Licenciatura) Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal "Isolation, characterization and evaluation of the biotechnological potential of bacteria present in the sponge Dysidea fragilis" (TESE/DISSERTAÇÃO)	14

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2023/04/01 - Atual	Investigador (Investigação)	Glial Cell Biology Groups, and Molecular and Analytical Medicine Lab, Portugal
	Universidade do Porto Faculdade de Medicina, Portugal (...)
2018/01/05 - 2018/08/31	Investigador (Investigação)	3B´s Research Group, I3Bs - Biomaterials, Biodegradables and Biomimetics of University of Minho, Headquartes of the European Institute of Escellence on Tissue Engineering and Regenerative Medicine, Portugal

Outros

	Categoria Profissional Instituição de acolhimento	Empregador
2016/09/19 - 2017/08/03	Master student researcher	Laboratório Associado ICVS 3B's, Portugal
	3B´s Research Group, I3Bs - Biomaterials, Biodegradables and Biomimetics of University of Minho, Headquartes of the European Institute of Escellence on Tissue Engineering and Regenerative Medicine, Portugal (...)

Projetos

Bolsa

	Designação	Financiadores
2018/09/01 - Atual	PhD student in Tissue Engineering, Regenerative Medicine and Stem Cells (TERM&SC) PD/BD/143044/2018 Bolseiro de Doutoramento 3B´s Research Group, I3Bs - Biomaterials, Biodegradables and Biomimetics of University of Minho, Headquartes of the European Institute of Escellence on Tissue Engineering and Regenerative Medicine, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2016/06 - 2021/07	BlueHuman EAPA_151/2016 Investigador 3B´s Research Group, I3Bs - Biomaterials, Biodegradables and Biomimetics of University of Minho, Headquartes of the European Institute of Escellence on Tissue Engineering and Regenerative Medicine, Portugal	Interreg Europe Concluído
2018/01/05 - 2018/08/31	Instituto de Bioingeniería en Red para el Envejecimiento Saludable (IBEROS) BIM_November_2017_IBEROS_01 Bolseiro de Integração na Investigação 3B´s Research Group, I3Bs - Biomaterials, Biodegradables and Biomimetics of University of Minho, Headquartes of the European Institute of Escellence on Tissue Engineering and Regenerative Medicine, Portugal	Concluído

Projeto

	Designação	Financiadores
2023/04/01 - Atual	LIFESAVER (H2020-LC-GD-2020-3-101036702-LIFESAVER) H2020-LC-GD-2020-3-101036702-LIFESAVER Senior Research Technician Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade do Porto Faculdade de Medicina, Portugal	Horizon 2020 Em curso

Outro

	Designação	Financiadores
2020/10/01 - 2023/09/30	ATLANDIDA. Platform for the monitoring of the North Atlantic ocean and tools for the sustainable exploitation of the marine resources NORTE-01-0145-FEDER-000040 Investigador 3B´s Research Group, I3Bs - Biomaterials, Biodegradables and Biomimetics of University of Minho, Headquartes of the European Institute of Escellence on Tissue Engineering and Regenerative Medicine, Portugal	Em curso

Produções

Publicações

Artigo em revista	Tiago H. Silva; Duarte Nuno Carvalho; Alves, Ana L.; Rita O. Sousa; Mariana Almeida; Reis, Rui L.. "Blue tissue engineering: Approaches for the regeneration of different tissues using marine origin compounds". (2023): Em revisão Duarte Nuno Carvalho; Cristiana Gonçalves; Rita O. Sousa; J. Miguel Oliveira; Reis, Rui L.; Tiago H. Silva. Autor correspondente: Tiago H. Silva. "Extraction and purification of biopolymers from marine origin sources envisaging their use for biotechnological approach". Marine Biotechnology (2023): Submetido Carvalho, Duarte Nuno; Dani, Sophie; Sotelo, Carmen G; Pérez-Martín, Ricardo I; Reis, Rui L; Silva, Tiago H; Gelinsky, Michael. "Assessing non-synthetic crosslinkers in biomaterial inks based on polymers of marine origin to increase the shape fidelity in 3D extrusion printing". Biomedical Materials 18 5 (2023): 055017. http://dx.doi.org/10.1088/1748-605x/acecec. Acesso aberto • Aceite para publicação • 10.1088/1748-605x/acecec Duarte Nuno Carvalho; Gelinsky, Michael; Williams, David S.; Mearns-Spragg, Andrew; Reis, Rui L.; Silva, Tiago H.. Autor correspondente: Silva, Tiago H.. "Marine collagen-chitosan-fucoidan/chondroitin sulfate cryo-biomaterials loaded with primary human cells envisaging cartilage tissue engineering". International Journal of Biological Macromolecules 241 (2023): 124510. http://dx.doi.org/10.1016/j.ijbiomac.2023.124510. Aceite para publicação • 10.1016/j.ijbiomac.2023.124510 Duarte Nuno Carvalho; Flávia C. M. Lobo; Luísa C. Rodrigues; Emanuel M. Fernandes; David S. Williams; Andrew Mearns-Spragg; Carmen G. Sotelo; et al. "Advanced Polymeric Membranes as Biomaterials Based on Marine Sources Envisaging the Regeneration of Human Tissues". Gels (2023): https://doi.org/10.3390/gels9030247. 10.3390/gels9030247 Duarte Nuno Carvalho; Cristiana Gonçalves; Joaquim Miguel Oliveira; David S. Williams; Andrew Mearns-Spragg; Rui L. Reis; Tiago H. Silva. "A Design of Experiments (DoE) Approach to Optimize Cryogel Manufacturing for Tissue Engineering Applications". Polymers (2022): https://doi.org/10.3390/polym14102026. 10.3390/polym14102026 Duarte Nuno Carvalho; David S. Williams; Carmen G. Sotelo; Ricardo I. Perez-Martín; Andrew Mearns-Spragg; Reis, Rui L.; Tiago H. Silva. Autor correspondente: Tiago H. Silva. "Marine origin biomaterials using a compressive and absorption methodology as cell-laden hydrogel envisaging cartilage tissue engineering". Biomaterials Advances (2022): 212843-212843. http://dx.doi.org/10.1016/j.bioadv.2022.212843. 10.1016/j.bioadv.2022.212843 Cristiana Gonçalves; Duarte Nuno Carvalho; Tiago H. Silva; Rui L. Reis; J. Miguel Oliveira. "Engineering of Viscosupplement Biomaterials for Treatment of Osteoarthritis: A Comprehensive Review". Advanced Engineering Materials (2022): 2101541-2101541. https://doi.org/10.1002/adem.202101541. 10.1002/adem.202101541 Duarte Nuno Carvalho. "Marine origin materials on biomaterials and advanced therapies to cartilage tissue engineering and regenerative medicine". Biomaterials Science (2021): http://dx.doi.org/10.1039/d1bm00809a. 10.1039/d1bm00809a Duarte Nuno Carvalho. "Innovative methodology for marine collagen-chitosan-fucoidan hydrogels production, tailoring rheological properties towards biomedical application". Green Chemistry (2021): http://dx.doi.org/10.1039/d1gc02223g. 10.1039/d1gc02223g Duarte Nuno Carvalho; Rita López-Cebral; Sousa, Rita O.; Ana L Alves; Lara L Reys; Simone S Silva; J Miguel Oliveira; Rui L Reis; Tiago H Silva. "Marine collagen-chitosan-fucoidan cryogels as cell-laden biocomposites envisaging tissue engineering". Biomedical Materials 15 5 (2020): 055030-055030. https://doi.org/10.1088/1748-605X/ab9f04. 10.1088/1748-605X/ab9f04 Rita O. Sousa; Eva Martins; Duarte Nuno Carvalho; Ana L. Alves; Catarina Oliveira; Ana Rita C. Duarte; Tiago H. Silva; Rui L. Reis. "Collagen from Atlantic cod (Gadus morhua) skins extracted using CO2 acidified water with potential application in healthcare". Journal of Polymer Research 27 3 (2020): https://doi.org/10.1007/s10965-020-02048-x. 10.1007/s10965-020-02048-x Sousa, Rita O.; Alves, Ana L.; Carvalho, Duarte Nuno; Martins, Eva; Oliveira, Catarina; Silva, Tiago H.; Reis, Rui L.. "Acid and enzymatic extraction of collagen from Atlantic cod (Gadus Morhua) swim bladders envisaging health-related applications". Journal of Biomaterials Science, Polymer Edition (2019): 1-18. http://dx.doi.org/10.1080/09205063.2019.1669313. 10.1080/09205063.2019.1669313
Capítulo de livro	Duarte Nuno Carvalho; Ana Rita Inácio; Rita O. Sousa; Reis, Rui L.; Tiago H. Silva. "Seaweed Polysaccharides as sustainable building blocks for biomaterials in Tissue Engineering". In Sustainable Seaweed Technologies. Elsevier, 2020. 10.1016/c2018-0-01462-0
Poster em conferência	Duarte Nuno Carvalho; Sophie Dani; Carmen G. Sotelo; Ricardo I. Perez-Martín; Reis, Rui L.; Tiago H. Silva. "3D extrusion printing of marine collagen-chitosan-fucoidan inks: Evaluation of shape fidelity and cytocompatibility". Trabalho apresentado em 33rd Annual conference of the European Society for biomaterials (ESB), Davos, Switzerland, 2023. Evelyn C. Santos; Duarte Nuno Carvalho; Daniel C. Moreira; Ricardo S. Reis; Joao B. Relvas; Miguel A. D. Neves; Ines Mendes Pinto. "A miniaturized point-of-care biosensor as a precise molecular analysis tool for monitoring neurodegeneration". Trabalho apresentado em 15th Bienniel ISN Satellite Meeting on Myelin biology, 2023. Diogo C. Fernandes; Canadas, Raphael F.; Sousa, Rita O.; Carvalho, Duarte Nuno; Silva, Tiago H.; Reis, Rui L.. "Biophysical properties regulate coatings’ performance in neuronal culture according to a performance factor-based mathematical model". Trabalho apresentado em ForeCast, 2021. Carvalho, Duarte Nuno; Cristiana Gonçalves; J. Miguel Oliveira; Reis, Rui L.; Silva, Tiago H.. "A statistical design of experiments (DoE) applied to tissue engineering scaffolding manufacturing by combination of marine-origin biopolymers". Trabalho apresentado em ForeCast, 2021. Diogo Castro Fernandes; Raphael F. Canadas; Rita O. Sousa; Duarte Nuno Carvalho; Tiago H. Silva; Rui L. Reis; J. Miguel Oliveira. "Morphological modulation of differentiating neuroblastoma cells into neurons using natural biomaterials physical and chemical properties". Trabalho apresentado em TermStem, 2019. Duarte Nuno Carvalho; Rita Lopez-Cebral; J. Miguel Oliveira; Rui L. Reis. "Development of hydrogels-based on marine biopolymers envisaging cartilage tissue engineering and regenerative medicine". Trabalho apresentado em TermStem, 2019. 10.1117/12.841758 Duarte Nuno Carvalho; Lopez-Cebral, Rita; Sousa, Rita O.; Reys, Lara L.; Oliveira, Joaquim Miguel; Reis, Rui L.; Silva, Tiago H.. "Marine origin biopolymers on the development of cryo-system gels envisaging cartilage tissue engineering and regenerative medicine". Trabalho apresentado em 30th Annual conference of the European Society for Biomaterials (ESB), 2019. Duarte, Filipa; Carvalho, Duarte Nuno; Reis, Rui L.; Silva, Tiago H.. "Angiogenic peptides grafted onto squid chitosan to improve tissue engineering". Trabalho apresentado em 1st Discoveries Forum on regenerative and precision medicine, 2019. 10.1115/ijtc2008-71224 Duarte Nuno Carvalho; Lopez-Cebral, Rita; Rita O. Sousa; J. Miguel Oliveira; Rui L. Reis; Tiago H. Silva. "Development of innovative scaffolds-based in marine origin biopolymers envisaging cartilage tissue engineering and regenerative medicine". Trabalho apresentado em 1st Discoveries Forum on regenerative and precision medicine, 2019. Fernandes, Diogo Castro; Canadas, Raphael F.; Sousa, Rita O.; Carvalho, Duarte Nuno; Silva, Tiago H.; Reis, Rui L.. "Neural Differentiation Enhancement using natural Biomaterials". Trabalho apresentado em FoReCast, 2019. 10.1364/bio.1999.atuc2 Duarte, Filipa; Duarte Nuno Carvalho; Reis, Rui L.; Silva, Tiago H.. "Functionalization of squid chitosan with angiogenic peptides for the development of new biomaterials". Trabalho apresentado em 1st conference of Achilles, 2019. Duarte Nuno Carvalho; Lopez-Cebral, Rita; Sousa, Rita O.; Reys, Lara L.; Oliveira, Joaquim Miguel; Reis, Rui L.; Silva, Tiago H.. "Marine origin biopolymers on the development of innovative scaffolds envisaging cartilage tissue engineering and regenerative medicine". Trabalho apresentado em 1st conference of Achiles, 2019. Duarte Nuno Carvalho; Duarte Nuno Carvalho; Rita Lopez-Cebral; Rui L. Reis; Tiago H. Silva. "Marine origin biopolymers on the development of hydrogels for articular cartilage tissue engineering: processing methodologies and main characteristics". Trabalho apresentado em Chem2nature Final Conference, 2018. Rita O. Sousa; Ana Luísa Alves; Duarte Nuno Carvalho; Eva Martins; Catarina Oliveira; Tiago H. Silva; Rui L. Reis. "Production and biomedical potential of collagen from codfish swim-bladder". Trabalho apresentado em 29th Annual Meeting of the European Society for Biomaterials (ESB), 2018. Rita O. Sousa; Eva Marins; Duarte Nuno Carvalho; Ana Luísa Alves; Catarina Oliveira; Tiago H. Silva; Rui L. Reis. "Collagen extraction from codfish (Gadus morhua) skins using CO2 acidified water". Trabalho apresentado em CHEM2NATURE and GENE2SKIN summer school, 2018. Duarte Nuno Carvalho; Rita O. Sousa; Ana Luísa Alves; Eva Martins; Tiago H. Silva; Rui L. Reis. "Extraction of collagen type II from jellyfish, its characterization and further processing envisaging cartilage tissue engineering". Trabalho apresentado em CHEM2NATURE First School, 2016. Rita O. Sousa; Duarte Nuno Carvalho; Ana Luísa Alves; Eva Martins; Tiago H. Silva; Rui L. Reis. "Valorization of cod by-products by extraction of biopolymers with biomedical potential". Trabalho apresentado em CHEM2NATURE First School, 2016. Duarte Nuno Carvalho; Inês A. Franco; Cristiana I. Gastão; Susana M. F. Ferreira; Maria Manuel Sampaio. "Isolation, characterization and evaluation of the biotechnological potential of bacteria present in the sponge Dysidea fragilis". Trabalho apresentado em IMMR 2016 / MARE – Marine and Environmental Sciences Centre, 2016.
Recurso online	Duarte Nuno Carvalho; Tiago H. Silva. BlueHuman project promotional video. 2021. https://www.youtube.com/watch?v=OH1u0jw7jYs&ab_channel=CentroTecnol%C3%B3gicodelMarFundaci%C3%B3nCETMAR. Duarte Nuno Carvalho; Tiago H. Silva. BlueHuman project promotional video. 2021. https://www.youtube.com/watch?v=U2AO0vd9a8w&t=15s&ab_channel=CentroTecnol%C3%B3gicodelMarFundaci%C3%B3nCETMAR.
Tese / Dissertação	Carvalho, Duarte. "Marine collagen-chitosan-fucoidan cryogels as cell-laden biocomposites envisaging cartilage tissue engineering". Mestrado, Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, 2017. Carvalho, Duarte Nuno. "Isolation, Characterization and evaluation of the biotechnological potential of bacteria present in the sponge Dysidea fragilis". Licenciatura, Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, 2015.

Propriedade Intelectual

Patente

Duarte Nuno Carvalho; Sousa, Rita O.. 2021. "Eco-Friendly Gels from Marine Biopolymers, Products and uses Thereof". Portugal.

Atividades

Apresentação oral de trabalho

	Título da apresentação	Nome do evento Anfitrião (Local do evento)
2023/01/17	Innovative compressive and absorption methodology for the production of hydrogels (CAMPH) based in marine biopolymers for tissue engineering	14th International Meeting of the Portuguese Carbohydrate Group - GLUPOR 14, Sociedade Portuguesa da Química, NOVA School of Science and Technology, NOVA University of Lisbon, Universidade Nova de Lisboa (Lisboa, Portugal)
2022/05/24	Cell-laden marine collagen/chitosan/fucoidan hydrogel produced with an innovative compressive and absorption methodology envisaging cartilage tissue engineering	MIcSeaOnMed workshop 3bs Research Group, University of Minho (Guimarães, Portugal)

Organização de evento

	Nome do evento Tipo de evento (Tipo de participação)	Instituição / Organização
2023/04/03 - 2023/04/04	International workshop: REMIX (2023/04/03 - 2023/04/04) Conferência (Coorganizador)	3B´s Research Group, I3Bs - Biomaterials, Biodegradables and Biomimetics of University of Minho, Headquartes of the European Institute of Escellence on Tissue Engineering and Regenerative Medicine, Portugal
2022/05/24 - 2022/05/24	International conference/workshop: MIcSeaOnMed (2022/05/24) Conferência (Membro da Comissão Organizadora)	3B´s Research Group, I3Bs - Biomaterials, Biodegradables and Biomimetics of University of Minho, Headquartes of the European Institute of Escellence on Tissue Engineering and Regenerative Medicine, Portugal