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Isabel Ferreira obtained her PhD in Pharmaceuticals Sciences in 2021 by the Faculty of Pharmacy, University of Coimbra, in which she focused on the role of danger signals in allergic diseases to low molecular weight chemicals. Isabel has been working in the field of Immunology and Toxicology research for 10 years, but in the last 8 years, she's been involved in the study of skin and respiratory sensitization as well as in the development of non-animal alternative approaches. Throughout her scientific path, Isabel published 22 papers in SCI indexed journals and 2 book chapters. She also contributed for 4 provisional patent applications, participated in several financed projects both as a researcher or a team member and is currently a co-supervisor of a MSc student. She has been recently awarded with a Colgate-Palmolive Grant for Alternative Research (2021).
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Identificação

Identificação pessoal

Nome completo
Isabel Cristina do Vale Ferreira

Nomes de citação

  • Ferreira, Isabel

Identificadores de autor

Ciência ID
5714-6B8A-C2B7
ORCID iD
0000-0002-4934-917X

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Imunologia
  • Ciências Médicas e da Saúde - Medicina Básica - Toxicologia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Português (Idioma materno)
Formação
Grau Classificação
2015 - 2021/09/10
Concluído
 Ciências Farmacêuticas (Doutoramento)
Especialização em Farmacologia e Farmacoterapia
Universidade de Coimbra Faculdade de Farmácia, Portugal
 Distinção e Louvor por unanimidade
2009 - 2011
Concluído
 Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Pharmacological screening of essential oils for identification of lead compounds to target Inflammatory Bowel Disease" (TESE/DISSERTAÇÃO)
 17
2005 - 2009
Concluído
 Biologia (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
 14
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2021/10/01 - 2022/09/30 Pós-doutorado (Investigação) Centro de Neurociências e Biologia Celular, Universidade de Coimbra, Portugal
2020/06 - 2021/03/31 Investigador (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Centro de Neurociências e Biologia Celular, Universidade de Coimbra, Portugal
2014 - 2015 Investigador (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2012 - 2013 Investigador (Investigação) Universidade de Coimbra Faculdade de Farmácia, Portugal
Universidade de Coimbra Faculdade de Farmácia, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2023/01 - 2024/02 Professor Associado Convidado (Docente Universitário) Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/09/01 - 2021/08/31 Professor Auxiliar Convidado (Docente Universitário) Universidade de Coimbra Faculdade de Farmácia, Portugal
2014/11 - 2014/11 Monitor (Docente Universitário) Universidade de Coimbra Faculdade de Farmácia, Portugal
Universidade de Coimbra Faculdade de Farmácia, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2023/10 - Atual Manager, Projects and Tech Transfer Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal
2016 - 2021 PhD Student Centro de Neurociências e Biologia Celular, Universidade de Coimbra, Portugal
2019/12 - 2020/05 Carrer break - Maternity Leave Centro de Neurociências e Biologia Celular, Universidade de Coimbra, Portugal
Projetos

Bolsa

Designação Financiadores
2021/10/01 - 2022/09/30 Development of a Defined Approach for Respiratory Sensitization Hazard Assessment
Colgate Palmolive Grant for Alternative Research 2021
Investigador responsável
Colgate Palmolive Co

Projeto

Designação Financiadores
2021 - Atual Dissecting the mechanism by which haptens disrupt lysosomes and activate NLRP3 inflammasome: the missing link in chemical allergic reactions physiopathology
EPIC-XS project 265
Outra
Horizon 2020 European Innovation Council Fast Track to Innovation
Em curso
2021/04/01 - 2021/08/31 PulManCar: Microparticles design for active compounds pulmonary delivery using insulin as model
POCI-01-0145-FEDER-029560
Bolseiro de Investigação
QOPNA & LAQV-Requimte, University of Aveiro, Portugal
2018/07/26 - 2021/07/25 Skin allergens: molecules with an improbable therapeutic application for Alzheimer's disease
PTDC/MED-FAR/29369/2017
Outra
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2020/06 - 2021/03 HEALTHYAGING 2020
CENTRO-01-0145- FEDER-000012
Bolseiro de Investigação
European Regional Development Fund
2018 - 2021 Optimization of a defined approach for skin sensitizer potency integrating in silico, in chemico and in vitro cell data for classifying chemicals accordingly to five categories (extreme, strong, moderate, weak and non-sensitizer)
Outra
Cosmetics Europe
Concluído
2014 - 2015 In chemico, in silico and in vitro dendritic cell modeling to predict human respiratory allergens
2014-07
Bolseiro de Investigação
Johns Hopkins University Center for Alternatives to Animal Testing
Concluído
2012 - 2013 NutraCork: Phenolic compounds of cork: cosmetic validation, alimentary evaluation and nutraceutic potential
(Ref 21597)
Bolseiro de Investigação
Projecto Estratégico Nacional (QREN)
Produções

Publicações

Artigo em revista
  1. Fernanda Lopes Conte; Ana Catarina Pereira; Gonçalo Brites; Isabel Ferreira; Ana Cristina Silva; Ana Isabel Sebastião; Patrícia Matos; et al. "Exploring the antioxidant, anti-inflammatory and antiallergic potential of Brazilian propolis in monocytes". Phytomedicine Plus (2022): https://publons.com/publon/42077702/.
    10.1016/J.PHYPLU.2022.100231
  2. Brites, Gonçalo Sousa; Ferreira, Isabel; Sebastião, Ana Isabel; Silva, Ana; Carrascal, Mylene; Neves, Bruno Miguel; Cruz, Maria T.. "Allergic contact dermatitis: From pathophysiology to development of new preventive strategies". Pharmacological Research 162 (2020): 105282. http://dx.doi.org/10.1016/j.phrs.2020.105282.
    10.1016/j.phrs.2020.105282
  3. Sebastião, Ana Isabel; Ferreira, Isabel; Brites, Gonçalo; Silva, Ana; Neves, Bruno Miguel; Teresa Cruz, Maria. "NLRP3 Inflammasome and Allergic Contact Dermatitis: A Connection to Demystify". Pharmaceutics 12 9 (2020): 867. http://dx.doi.org/10.3390/pharmaceutics12090867.
    10.3390/pharmaceutics12090867
  4. Silva, Filipa A. L. S.; Brites, Gonçalo; Ferreira, Isabel; Silva, Ana; Miguel Neves, Bruno; Costa Pereira, Jorge L. G. F. S.; Cruz, Maria T.. "Evaluating Skin Sensitization Via Soft and Hard Multivariate Modeling". International Journal of Toxicology 39 6 (2020): 547-559. http://dx.doi.org/10.1177/1091581820944395.
    10.1177/1091581820944395
  5. Rodrigues, Vanessa; Cabral, Célia; Évora, Leisa; Ferreira, Isabel; Cavaleiro, Carlos; Cruz, Maria Teresa; Salgueiro, Lígia. "Chemical composition, anti-inflammatory activity and cytotoxicity of Thymus zygis L. subsp. sylvestris (Hoffmanns. & Link) Cout. essential oil and its main compounds". Arabian Journal of Chemistry 12 8 (2019): 3236-3243. http://dx.doi.org/10.1016/j.arabjc.2015.08.026.
    10.1016/j.arabjc.2015.08.026
  6. Fernandes, Pedro A. R.; Ferreira, Sónia S.; Bastos, Rita; Ferreira, Isabel; Cruz, Maria T.; Pinto, António; Coelho, Elisabete; et al. "Apple Pomace Extract as a Sustainable Food Ingredient". Antioxidants 8 6 (2019): 189. http://dx.doi.org/10.3390/antiox8060189.
    10.3390/antiox8060189
  7. Ferreira, Isabel; Silva, Ana; Martins, João Demétrio; Neves, Bruno Miguel; Cruz, Maria Teresa. "Nature and kinetics of redox imbalance triggered by respiratory and skin chemical sensitizers on the human monocytic cell line THP-1". Redox Biology 16 (2018): 75-86. http://dx.doi.org/10.1016/j.redox.2018.02.002.
    10.1016/j.redox.2018.02.002
  8. Matos, Patrícia; Figueirinha, Artur; Ferreira, Isabel; Cruz, Maria Teresa; Batista, Maria Teresa. "Acanthus mollis L. leaves as source of anti-inflammatory and antioxidant phytoconstituents". Natural Product Research 33 12 (2018): 1824-1827. http://dx.doi.org/10.1080/14786419.2018.1437438.
    10.1080/14786419.2018.1437438
  9. Melo, Tânia; Marques, Sara S.; Ferreira, Isabel; Cruz, Maria Teresa; Domingues, Pedro; Segundo, Marcela A.; Domingues, Maria Rosário Marques. "New Insights into the Anti-Inflammatory and Antioxidant Properties of Nitrated Phospholipids". Lipids 53 1 (2018): 117-131. http://dx.doi.org/10.1002/lipd.12007.
    10.1002/lipd.12007
  10. Santos, Sónia; Trindade, Stephanie; Oliveira, Catia; Parreira, Paula; Rosa, Daniela; Duarte, Maria; Ferreira, Isabel; et al. "Lipophilic Fraction of Cultivated Bifurcaria bifurcata R. Ross: Detailed Composition and In Vitro Prospection of Current Challenging Bioactive Properties". Marine Drugs 15 11 (2017): 340. http://dx.doi.org/10.3390/md15110340.
    10.3390/md15110340
  11. Cruz, Maria Teresa; Ferreira, Isabel; Liberal, Joana; D Martins, Joao; Silva, Ana; Neves, Bruno Miguel. "Inflammasome in Dendritic Cells Immunobiology: Implications to Diseases and Therapeutic Strategies". Current Drug Targets 18 9 (2017): http://dx.doi.org/10.2174/1389450117666160921144830.
    10.2174/1389450117666160921144830
  12. da Costa, Elisabete; Melo, Tânia; Moreira, Ana; Bernardo, Carina; Helguero, Luisa; Ferreira, Isabel; Cruz, Maria; et al. "Valorization of Lipids from Gracilaria sp. through Lipidomics and Decoding of Antiproliferative and Anti-Inflammatory Activity". Marine Drugs 15 3 (2017): 62. http://dx.doi.org/10.3390/md15030062.
    10.3390/md15030062
  13. Martins, Vitor M.R.; Simões, Joana; Ferreira, Isabel; Cruz, Maria Teresa; Domingues, M. Rosário; Coimbra, Manuel A.. "In vitro macrophage nitric oxide production by Pterospartum tridentatum (L.) Willk. inflorescence polysaccharides". Carbohydrate Polymers 157 (2017): 176-184. http://dx.doi.org/10.1016/j.carbpol.2016.09.079.
    10.1016/j.carbpol.2016.09.079
  14. Francisco V; Figueirinha A; Costa G; Liberal J; Ferreira I; Lopes MC; García-Rodríguez C; Cruz MT; Batista MT. "The Flavone Luteolin Inhibits Liver X Receptor Activation.". Journal of natural products (2016): http://europepmc.org/abstract/med/27135143.
    10.1021/acs.jnatprod.6b00146
  15. Martins JD; Maciel EA; Silva A; Ferreira I; Ricardo F; Domingues P; Neves BM; Domingues MR; Cruz MT. "Phospholipidomic Profile Variation on THP-1 Cells Exposed to Skin or Respiratory Sensitizers and Respiratory Irritant.". Journal of cellular physiology (2016): http://europepmc.org/abstract/med/26946329.
    10.1002/jcp.25365
  16. Martins, J. D.; Silva, A.; Ferreira, I.; Gonçalo, M.; Custódio, J. B. A.; Lopes, M. C.; Domingues, M. R. M.; Neves, B. M.; Cruz, M. T.. "Adenosine diphosphate involvement in THP-1 maturation triggered by the contact allergen 1-fluoro-2,4-dinitrobenzene". Toxicology Research 5 6 (2016): 1512-1521. http://dx.doi.org/10.1039/c6tx00240d.
    10.1039/c6tx00240d
  17. Martins JD; Liberal J; Silva A; Ferreira I; Neves BM; Cruz MT. "Autophagy and inflammasome interplay.". DNA and cell biology (2015): http://europepmc.org/abstract/med/25757059.
    10.1089/dna.2014.2752
  18. Rufino AT; Ferreira I; Judas F; Salgueiro L; Lopes MC; Cavaleiro C; Mendes AF. "Differential effects of the essential oils of Lavandula luisieri and Eryngium duriaei subsp. juresianum in cell models of two chronic inflammatory diseases.". Pharmaceutical biology (2015): http://europepmc.org/abstract/med/25612776.
    10.3109/13880209.2014.970701
  19. Luís A; Martins JD; Silva A; Ferreira I; Cruz MT; Neves BM. "Oxidative stress-dependent activation of the eIF2a–ATF4 unfolded protein response branch by skin sensitizer 1-fluoro-2,4-dinitrobenzene modulates dendritic-like cell maturation and inflammatory status in a biphasic manner [corrected].". Free radical biology & medicine (2014): http://europepmc.org/abstract/med/25236743.
    10.1016/j.freeradbiomed.2014.09.008
  20. Rodrigues, V; Cabral, C.; Evora, L.; Ferreira, I; Pereira, C.; Cavaleiro, C.; Cruz, M. T.; Salgueiro, L.. "Anti-inflammatory effects of Thymus zygis subsp sylvestris essential oil in LPS-stimulated macrophages and microglia cells". Planta Medica (2014): https://publons.com/publon/10621810/.
  21. Abu-Darwish MS; Cabral C; Ferreira IV; Gonçalves MJ; Cavaleiro C; Cruz MT; Al-bdour TH; Salgueiro L. "Essential oil of common sage (Salvia officinalis L.) from Jordan: assessment of safety in mammalian cells and its antifungal and anti-inflammatory potential.". BioMed research international (2013): http://europepmc.org/abstract/med/24224168.
    10.1155/2013/538940
  22. Búfalo MC; Ferreira I; Costa G; Francisco V; Liberal J; Cruz MT; Lopes MC; Batista MT; Sforcin JM. "Propolis and its constituent caffeic acid suppress LPS-stimulated pro-inflammatory response by blocking NF-¿B and MAPK activation in macrophages.". Journal of ethnopharmacology (2013): http://europepmc.org/abstract/med/23770030.
    10.1016/j.jep.2013.06.004
Capítulo de livro
  1. Neves, Bruno Miguel; Martins, João Demétrio; Ferreira, Isabel; Silva, Ana; Cruz, Maria Teresa. "In Vitro Dendritic Cell-Based Test for Skin Sensitizers Identification and Potency Estimation". In Alternatives for Dermal Toxicity Testing, 417-435. Springer International Publishing, 2017.
    10.1007/978-3-319-50353-0_29
  2. Joana Liberal; Isabel V. Ferreira; Eliza Cardoso; Ana Silva; Ariane Bartolomeu; João Martins; Karina Santiago; et al. "Anti-Inflammatory Activity of the Honeybee Plant- Derived Products Honey, Pollen and Propolis". In Chemistry, Biology and Potential Applications of Honeybee Plant- Derived Products, 313-346. BENTHAM SCIENCE PUBLISHERS, 2016.
    10.2174/9781681082370116010012
Poster em conferência
  1. Brites, G; Silva, Filipa; Ferreira, Isabel; Silva, Ana; Carrascal, Mylene; Neves, Bruno; Rosete, Teresa. "Managing allergic contact dermatitis: screening of molecules with potential for preventing the disease". Trabalho apresentado em 24th World Congress of Dermatology, 2019.
  2. Pereira, Ana Catarina; Ferreira, Isabel; Neves, Bruno; Morais, S; Madeira, N; Cruz, Maria Teresa; Pereira, Cláudia. "Mitochondria-Associated Membranes: the putative link between cellular stress and inflammasome activation in Bipolar Disorder". Trabalho apresentado em Encontro Nacional da Sociedade Portuguesa de Psiquiatria e Saúde Mental (SPPSM)| II Encontro das Secções, 2019.
  3. Pereira, Ana Catarina; Ferreira, Isabel; Neves, Bruno; Madeira, N; Cruz, Maria Teresa; Pereira, Cláudia. "Resposta ao stresse celular em células do sistema imune inato na doença Bipolar". Trabalho apresentado em 2º Semina´rio da Sociedade Portuguesa para o Estudo da Saúde Mental - SPESM, 2018.
  4. Ferreira, Isabel; Silva, AC; Martins, JD; Neves, BM; Cruz, MT. "Respiratory and skin allergies: a matter of differential ROS origin and kinetics?". Trabalho apresentado em 14th Congress European Society of Contact Dermatitis, 2018.
  5. Pereira, Ana Catarina; Ferreira, Isabel; Neves, Bruno; Cruz, Maria Teresa; Pereira, Cláudia. "Role of Mitochondria-Associated Membranes in the endoplasmic reticulum stress response in the innate immune system". Trabalho apresentado em MitoPorto International Symposium, 2018.
  6. Martins, VMR; Simões, J; Ferreira, Isabel; Cruz, Maria Teresa; Domingues, MR; Coimbra, MA. "The polysaccharides from Pterospartum Tridentatum (L.) willk. inflorescences and their contribution to in vitro macrophage nitric oxide production". Trabalho apresentado em XIXth EuroFoodChem Conference, 2017.
  7. Ferreira, Isabel; Silva, Ana; Martins, João Demétrio; Neves, Bruno Miguel; Cruz, Maria Teresa. "Differential modulation of toxicity pathways by respiratory and cutaneous allergens: interaction with physiopathology". Trabalho apresentado em International Conference on Occupational & Environmental Toxicology 2016 – ICOETOX 2016, 2016.
  8. Martins, Vitor MR; Simões, Joana; Ferreira, Isabel; Cruz, Maria Teresa; Domingues, Maria Rosário; Coimbra, Manuel A. "Structural characterization and macrophage immunostimulatory activity of polysaccharides present in the hot water extracts from P. tridentatum dried inflorescences.". Trabalho apresentado em 3rd International Congress on Cocoa, Coffee and Tea, 2015.
  9. Martins, Vitor MR; Simões, Joana; Ferreira, Isabel; Cruz, Maria Teresa; Domingues, Maria Rosário; Coimbra, Manuel A. "Structural features and macrophage immunostimulatory activity of the polysaccharides from Fraxinus angustifolia and Mentha suaveolens hot water extracts". Trabalho apresentado em 3rd International Congress on Cocoa, Coffee and Tea, 2015.
  10. Ferreira, Isabel; Liberal, Joana; Santos, T; Silva, S.; Cruz, Maria Teresa; Batista, Maria Teresa. "Bioactive Polyphenols from cork industry by-products". Trabalho apresentado em 62nd International Congress and Anual Meeting of the society for Medicinal Plant and Natural Product Research- GA2014, 2014.
  11. Rodrigues, V; Cabral, C; Évora, L; Ferreira, Isabel; Pereira, C; Cavaleiro, C; Cruz, MT; Salgueiro, L. "Anti-inflammatory effects of Thymus zygis subsp. sylvestris essential oil in LPS-stimulated macrophages and microglia cells.". Trabalho apresentado em 62nd International Congress and Anual Meeting of the society for Medicinal Plant and Natural Product Research- GA2014, 2014.
  12. Abu-Darwish, MS; Cabral, Célia; Ferreira, Isabel; Gonçalves, MJ; Cavaleiro, Carlos; Cruz, Maria Teresa; Al-bdour, TH; Salgueiro, Lígia. "Essential oils of Salvia officinalis L. from Jordan: Assessment of safety in mammalian cells, and their antifungal and anti-inflammatory potential". Trabalho apresentado em 5th International Congress on Medicinal and Aromatic Plants – CIPAM 2014, 2014.
  13. Martins, Vitor MR; Ferreira, Isabel; Cruz, Maria Teresa; Batista, Maria Teresa; Coimbra, Manuel A. "Pectic polysaccharides from the infusions of P. tridentatum, F. angustifolia and M. suaveolens: structural characterization and modulation of the inflammatory activity". Trabalho apresentado em 2nd International Congress on Cocoa, Coffee and Tea, 2013.
Resumo em conferência
  1. Brites, G. S.; Ferreira, I.; Silva, A.; Carrascal, M.; Vitorino, C.; Neves, B.; Cruz, M. T.. "Prevention of allergic contact dermatitis, myth or reality? Avoiding contact allergens: from basic research to development of a new medical device". 2021.
    10.1016/S0378-4274(21)00508-7
  2. Ferreira, I.; Brites, G.; Silva, A.; Cruz, M. T.; Neves, B. M.. "A defined approach for skin sensitization potency integrating in silico, in chemico and in vitro cell data". Trabalho apresentado em 55th Congress of the European Societies of Toxicology (Eurotox 2019), Helsínquia, 2019.
  3. Ferreira, Isabel; Silva, AC; Martins, JD; Neves, BM; Cruz, MT. "Respiratory and skin allergies: a matter of differential ROS origin and kinetics?". Trabalho apresentado em 14th Congress of the European Society of Contact Dermatitis (ESCD), Milan, 2018.
  4. Ferreira, IV; Liberal, J; Santos, T; Silva, S; Cruz, MT; Batista, MT. "Bioactive polyphenols from cork industry by-products". 2014.
    10.1055/s-0034-1394951
  5. Rodrigues, V; Cabral, C; Évora, L; Ferreira, Isabel; Pereira, C; Cavaleiro, C; Cruz, MT; Salgueiro, L. "Anti-inflammatory effects of Thymus zygis subsp. sylvestris essential oil in LPS-stimulated macrophages and microglia cells". 2014.
    10.1055/s-0034-1394737
  6. Ferreira, Isabel; Cavaleiro, C; Salgueiro, L; Lopes, MC; Mendes, AF. "Pharmacological screening of essential oils for identification of NF-kB and iNOS inhibitors in a human intestinal epithelial cell line". Trabalho apresentado em 6th European Congress of Pharmacology - EPHAR 2012, Granada, 2012.

Propriedade Intelectual

Pedido provisório de patente
  1. 2022. "Skin Allergens and uses thereof in prevention and/or treatment of neurodegenerative diseases".
  2. 2016. "Functionalized matrices to detect the haptenization capacity of xenobiotics".
  3. 2015. "An in silico and in vitro integrative approach to assess the potency of contact allergens".
  4. 2014. "Cork hydroglycolic extract, method for preparing same, formulations comprising said extract and use thereof".
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2022/02/09 Preventing allergic contact dermatitis: in vivo proof-of-concept using the local lymph node assay SPF Meeting 2022 - Sociedade Portuguesa de Farmacologia
(Porto)
2020/02 Unveiling new molecules with preventive properties for the management of allergic contact dermatitis L Reunião da Sociedade Portuguesa de Famacologia , XXXVIII Reunião de Farmacologia Clínica e XIX Reunião de Toxicologia
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2019/12  Connecting the dots in allergy: From basic science to translational research CIBB Meeting
CIBB (Coimbra, Portugal)
2019/09 A defined approach for skin sensitization potency integrating in silico, in chemico and in vitro cell data 55th Congress of the European Societies of Toxicology
European Societies of Toxicology (Helsinki, Finlândia)
2019/02 Role of Endoplasmic Reticulum-Mitochondria contacts in inflammasome activation during cellular stress conditions XLIX Annual Reunion of Pharmacology Portuguese Society
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2017/09 Immunostimulatory polysaccharides from the hot water extracts of prickled broom (P. tridentatum (L.) Willk) dried inflorescences 12ª Reunião do Grupo de Glúcidos
(Aveiro, Portugal)
2017/09 The polysaccharides from pterospartum tridentatum (l.) Willk. Inflorescences and their contribution to in vitro macrophage nitric oxide production XIXth EuroFoodChem Conference
(Budapest, Hungria)
2017/05 Using mass spectrometry techniques for the elucidation of structural features of immunostimulatory polysaccharides from medicinal plants aqueous extracts 6th Workshop Mass Spectrometry and Carbohydrates
(Aveiro, Portugal)
2017/02 Nature and kinetics of redox imbalance triggered by respiratory and skin chemical sensitizers in dendritic cells 47th Annual Reunion of Pharmacology Portuguese Society – SPF
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2016/05 Innate and adaptive immune systems working together: the case of Allergic Contact Dermatitis 4th Workshop of Immunology
University of Aveiro Mass Spectrometry Centre (Aveiro, Portugal)
2016/05 Estrutura e atividade imunoestimuladora dos polissacarídeos presentes em extratos aquosos de inflorescências secas de P. tridentatum III Seminário Alimentos e Manifestações Culturais Tradicionais e II Simpósio Internacional Alimentação e Cultura: Tradição e Inovação na Produção e Consumo de Alimentos
(Vila Real, Portugal)
2016/05 Dendritic cells surrogates for chemicals’ allergenicity screening 3rd Workshop of Immunology
(Aveiro, Portugal)
2013/04 Avaliação do potencial anti-inflamatório de compostos fenólicos extraídos de Quercus suber L.. Workshop de Produtos Naturais: Saúde e Investigação de Fármacos Workshop de Produtos Naturais: Saúde e Investigação de Fármacos
Escola Superior Agrária de Coimbra (Coimbra, Portugal)
2012/05 Pharmacological screening of essential oils for identification of NF-kB and iNOS inhibitors in a human intestinal epithelial cell line. 6th European Congress of Pharmacology - EPHAR 2012
(Granada, Espanha)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2021 - Atual Desenvolvimento de modelos não animais para detetar alergénios respiratórios
Coorientador
 Master's Degree in Applied Pharmacology (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2021/02 - 2021/07 Human Anatomy and Physiology II Bioanalytical Sciences (Licenciatura) Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/11/02 - 2020/11/13 Human Histology and Embryology Pharmaceutical Sciences (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2014/11 - 2014/11 Cellular and Molecular Biology Integrated Master's Degree in Pharmaceutical Sciences, Degree in Bioanalytical Sciences and Degree in Biomedical Pharmacy (Outros) Universidade de Coimbra Faculdade de Farmácia, Portugal

Tutoria

Tópico Nome do aluno
2017/09 - 2018/07 Deregulated inflammasome in Bipolar Disorder (BD): a matter of stress? Ana Catarina Pereira
2016/01 - 2016/09 Preparation and evaluation of the anti-inflammatory activity of novel glycosylated polyphenolic derivatives Josiane Magalhães Barbosa
2015/01 - 2015/07 Phenolic characterization and evaluation of the antioxidant and anti-inflammatory properties of Eriocephalus africanus and Geranium robertianum extracts Marcelo Dias Catarino
2014/11 - 2015/05 PROFITAPPLE (Project no. 38162) - Task: Purification and evaluation of anti-inflammatory activity of apple pomace extracts Sónia dos Santos Ferreira
2014/04 - 2014/06 Integration of concentrated apple juice production with valorization of its subproducts Amélia Vieira
2013/05 - 2013/07 Bioactivity of essential oils obtained from Rosmarinus officinalis L Leisa Nélida Pinto Évora
2012/03 - 2012/09 Efeito da própolis e de compostos isolados sobre a expressão de receptores, produção de citocinas e actividade fungicida de monócitos humanos Michelle Cristiane Búfalo
Distinções

Prémio

2018 Best Poster Award in the category of Basic Science
European Society of Contact Dermatitis, Alemanha